SCNN1A

General Information

Gene Name       : SCNN1A
Gene ID             : ENSG00000111319.12
Essential Gene : No

Functions

Localization

Domains (AlphaFold: SCNN1A)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878SCNN1AENSG00000111319.120.000.010.01ENCSR000AEF
HepG2SCNN1AENSG00000111319.129.375.647.50ENCSR985KAT
K562SCNN1AENSG00000111319.120.090.220.15ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for SCNN1A is not avaliable on ENCORE database.



Proteins bound to RNA
  • SCNN1A RNA is bound by 4 proteins.  







eCLIP assay for SCNN1A is not avaliable on ENCORE database.





4 proteins are bound to SCNN1A RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr1264564036456532-3'-UTR,intron-Distal6.2084417.22118HepG2UPF1
chr1264562816456428-3'-UTR,intron-Distal3.817585.03349HepG2AKAP1
chr1264564566456532-3'-UTR,intron-Distal5.3723210.84890HepG2AKAP1
chr1264571006457174-3'-UTR,CDS,intron-Distal,intron-Proximal3.336283.72765HepG2UPF1
chr1264714026471456-5'-UTR,CDS,intron-Distal,intron-Proximal4.272818.97597HepG2SF3B4
chr1264642516464362-intron-Distal,intron-Proximal3.922103.65854HepG2RBFOX2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for SCNN1A is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for SCNN1A is not available on ENCORE database.

  • 127 RBPs can affect the levels of SCNN1A.  








The Knockdown/knockout RNA-Seq assay for SCNN1A is not available on ENCORE database.





127 RBPs can affect the gene expression of SCNN1A :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
SCNN1AENSG00000111319.81044.15150602.065200.794207.666705.98900HepG2AATF
SCNN1AENSG00000111319.8314.716601093.30520-1.7966031.8420029.39890HepG2ABCF1
SCNN1AENSG00000111319.81377.75830833.645400.724706.086605.25540HepG2ACO1
SCNN1AENSG00000111319.8182.39260600.40770-1.7189026.7584024.28090HepG2ADAR
SCNN1AENSG00000111319.83571.252101162.337401.6193034.9420033.33040HepG2AKAP1
SCNN1AENSG00000111319.82952.746301504.971500.9722014.3516012.19640HepG2AKAP8
SCNN1AENSG00000111319.81239.30780837.345400.565505.629804.57000HepG2AKAP8L
SCNN1AENSG00000111319.81789.92670961.612900.896307.334506.08380HepG2ASCC1
SCNN1AENSG00000111319.82020.699901036.040700.9637031.9142030.03290HepG2AUH
SCNN1AENSG00000111319.81103.11040508.185901.1180014.1045012.30700HepG2BCLAF1
SCNN1AENSG00000111319.81822.37400995.333000.8725014.7721013.54160HepG2BOP1
SCNN1AENSG00000111319.81140.22790819.015100.477304.303602.78410HepG2BUD13
SCNN1AENSG00000111319.81670.44540857.723800.9615018.3551016.69390HepG2CALR
SCNN1AENSG00000111319.8926.260501237.13630-0.417502.403201.50200HepG2CCAR1
SCNN1AENSG00000111319.81077.66430767.103000.490304.664001.92810HepG2CEBPZ
SCNN1AENSG00000111319.8555.49680833.20370-0.584902.670502.01400HepG2CKAP4
SCNN1AENSG00000111319.82873.49020913.775701.6528049.3351046.98820HepG2CPSF6
SCNN1AENSG00000111319.81722.67450900.217600.9362017.4423014.95550HepG2CPSF7
SCNN1AENSG00000111319.879.38070361.23090-2.1861028.3130025.68040HepG2CSTF2
SCNN1AENSG00000111319.81191.17640895.576400.411402.179401.59830HepG2CELF1
SCNN1AENSG00000111319.82530.69760963.034001.3938083.3351080.50590HepG2DAZAP1
SCNN1AENSG00000111319.8458.92030770.88280-0.748304.189303.18760HepG2DDX19B
SCNN1AENSG00000111319.8353.24420663.19060-0.908804.571903.72490HepG2DDX21
SCNN1AENSG00000111319.8297.95370649.87000-1.125105.298804.02780HepG2DDX24
SCNN1AENSG00000111319.8226.12700538.04010-1.2506012.050409.67610HepG2DDX27
SCNN1AENSG00000111319.81723.253401113.165800.630402.755202.12940HepG2DDX3X
SCNN1AENSG00000111319.81145.81650642.854800.8337012.8962010.41320HepG2DDX52
SCNN1AENSG00000111319.81091.71020575.082200.924609.157107.84470HepG2DDX55
SCNN1AENSG00000111319.82044.155401037.657600.978107.684206.09840HepG2DDX59
SCNN1AENSG00000111319.82917.79870956.857601.6084034.0963032.28320HepG2DDX6
SCNN1AENSG00000111319.8357.89750797.50540-1.155907.012506.02810HepG2DKC1
SCNN1AENSG00000111319.81539.18360604.572901.3481044.2013041.85970HepG2DNAJC21
SCNN1AENSG00000111319.8456.42810766.99830-0.748806.899205.51200HepG2EEF2
SCNN1AENSG00000111319.81126.65550611.449800.881604.553903.12480HepG2AGO1
SCNN1AENSG00000111319.86182.27620919.229902.74950116.49220113.34780HepG2EIF2S1
SCNN1AENSG00000111319.8486.63730829.25780-0.769009.848607.82700HepG2EIF2S2
SCNN1AENSG00000111319.8223.19670626.86810-1.489807.504005.88080HepG2EIF3G
SCNN1AENSG00000111319.8774.816901239.07460-0.677306.835303.82610HepG2EIF3H
SCNN1AENSG00000111319.8216.944801015.55700-2.226907.809506.73650HepG2EIF4A3
SCNN1AENSG00000111319.8480.49590989.36020-1.042003.036702.31890HepG2EIF4B
SCNN1AENSG00000111319.81747.33080910.080900.9410015.5301013.71730HepG2EIF4G2
SCNN1AENSG00000111319.8493.53490946.98720-0.9402012.8154010.76920HepG2ESF1
SCNN1AENSG00000111319.8500.75160814.38920-0.701602.782301.94490HepG2EWSR1
SCNN1AENSG00000111319.81044.39230556.482200.9082015.7640013.05800HepG2FAM120A
SCNN1AENSG00000111319.8980.93830632.462800.633104.389902.99860HepG2FASTKD2
SCNN1AENSG00000111319.81842.04190950.882000.953903.628702.87090HepG2G3BP1
SCNN1AENSG00000111319.8449.272101010.10750-1.168803.421702.42450HepG2G3BP2
SCNN1AENSG00000111319.8240.25390554.36850-1.2063013.3944011.53940HepG2GEMIN5
SCNN1AENSG00000111319.8509.073301035.85180-1.0249012.2503010.99240HepG2GPKOW
SCNN1AENSG00000111319.8409.36390610.32200-0.576203.811501.59510HepG2GRWD1
SCNN1AENSG00000111319.81232.15080677.964600.861806.886604.60970HepG2GTF2F1
SCNN1AENSG00000111319.81454.76390795.734700.8703015.7346013.72760HepG2HDGF
SCNN1AENSG00000111319.81703.902701063.466000.680005.198903.26800HepG2HNRNPA0
SCNN1AENSG00000111319.8103.44980610.36510-2.5607048.7336046.72410HepG2HNRNPA1
SCNN1AENSG00000111319.8722.72400877.27140-0.279602.758602.08590HepG2HNRNPL
SCNN1AENSG00000111319.81878.72680988.531000.9263014.4667013.18210HepG2HNRNPLL
SCNN1AENSG00000111319.81108.34290761.592000.541205.775204.46300HepG2HNRNPM
SCNN1AENSG00000111319.81466.29650674.435701.1203036.0040034.04250HepG2HNRNPU
SCNN1AENSG00000111319.8976.92970688.912600.503808.602607.37790HepG2ILF2
SCNN1AENSG00000111319.82635.747201637.292000.686806.198404.32120HepG2KRR1
SCNN1AENSG00000111319.8853.830001306.86390-0.614104.780703.67750HepG2LARP4
SCNN1AENSG00000111319.8349.13180676.26140-0.9538011.395309.08070HepG2LIN28B
SCNN1AENSG00000111319.8347.012901025.92480-1.563904.806003.94900HepG2MAGOH
SCNN1AENSG00000111319.8428.225701031.51910-1.268303.835303.10240HepG2MATR3
SCNN1AENSG00000111319.81010.90930651.633500.633403.872502.63230HepG2METAP2
SCNN1AENSG00000111319.81343.76150893.329300.588906.939505.71560HepG2MSI2
SCNN1AENSG00000111319.81036.45900750.163600.466304.198802.70290HepG2NAA15
SCNN1AENSG00000111319.8409.82580582.44890-0.507103.797602.12430HepG2NIP7
SCNN1AENSG00000111319.82219.715301552.730100.515503.224601.67790HepG2NKRF
SCNN1AENSG00000111319.81736.79530954.938800.8628018.9271017.04740HepG2NOL12
SCNN1AENSG00000111319.8409.86360876.51030-1.0966014.4079012.84500HepG2NSUN2
SCNN1AENSG00000111319.82459.12050939.615201.3879026.1424024.00590HepG2PABPC4
SCNN1AENSG00000111319.8884.51990667.567700.405904.349203.31740HepG2PARN
SCNN1AENSG00000111319.8837.67890991.88690-0.243801.910201.39030HepG2PCBP1
SCNN1AENSG00000111319.8351.47030680.79420-0.953807.447905.82430HepG2PCBP2
SCNN1AENSG00000111319.8422.27100601.54160-0.510504.800203.85560HepG2PPIL4
SCNN1AENSG00000111319.8361.24160715.64780-0.986307.711705.77290HepG2PRPF6
SCNN1AENSG00000111319.81675.11210911.553400.8778015.4449014.19050HepG2PUF60
SCNN1AENSG00000111319.8624.84450967.63150-0.6310011.5724010.53400HepG2PUM1
SCNN1AENSG00000111319.8380.64850849.08380-1.157405.881905.04430HepG2PUS1
SCNN1AENSG00000111319.82471.000601093.010901.1767027.5214025.84890HepG2QKI
SCNN1AENSG00000111319.82791.832301364.558301.0327029.6283027.35490HepG2RBM15
SCNN1AENSG00000111319.8718.05610994.19620-0.469405.129404.47800HepG2RBM22
SCNN1AENSG00000111319.81393.22670992.028700.489902.514901.86880HepG2RBM25
SCNN1AENSG00000111319.8255.83900630.79070-1.3019013.9076011.62240HepG2RCC2
SCNN1AENSG00000111319.8452.943201123.25180-1.3103019.7749018.58410HepG2NELFE
SCNN1AENSG00000111319.8432.071801046.25180-1.2759029.4014027.77620HepG2RECQL
SCNN1AENSG00000111319.8864.12820605.850400.512204.817104.03120HepG2RPS19
SCNN1AENSG00000111319.8821.093901262.68200-0.620903.873102.92670HepG2RPS3A
SCNN1AENSG00000111319.8680.85000438.737900.633904.179403.23650HepG2RRP9
SCNN1AENSG00000111319.8909.44820608.055600.580705.088003.82380HepG2SERBP1
SCNN1AENSG00000111319.8194.03200804.24160-2.0513030.0976027.84290HepG2SF3A3
SCNN1AENSG00000111319.8313.35570978.45960-1.6427032.2876030.20230HepG2SF3B1
SCNN1AENSG00000111319.81091.84700700.407400.6404012.8375011.60920HepG2SMN1
SCNN1AENSG00000111319.81392.44170389.887801.836409.676706.93520HepG2SNRNP200
SCNN1AENSG00000111319.82861.203101088.704601.393905.988704.83370HepG2SNRNP70
SCNN1AENSG00000111319.82933.852501122.917901.3854079.5702077.84260HepG2SRFBP1
SCNN1AENSG00000111319.8430.300501096.79680-1.3499033.7830032.53060HepG2SRSF1
SCNN1AENSG00000111319.81760.87270899.999100.968209.129408.08070HepG2SRSF5
SCNN1AENSG00000111319.81390.212901014.069800.455006.812905.80060HepG2SRSF7
SCNN1AENSG00000111319.81692.84240892.342600.9237029.7085028.27230HepG2SRSF9
SCNN1AENSG00000111319.8105.14110974.97600-3.21300129.70560127.63140HepG2SSB
SCNN1AENSG00000111319.81889.04640737.241501.3573010.927808.70780HepG2STAU1
SCNN1AENSG00000111319.81558.149701098.668300.504003.526202.27000HepG2STIP1
SCNN1AENSG00000111319.81094.39150613.890700.834005.827604.09140HepG2SUB1
SCNN1AENSG00000111319.81506.320001023.570100.5573011.3058010.19260HepG2SUCLG1
SCNN1AENSG00000111319.81351.18420745.323700.8582013.9556011.96930HepG2SUPT6H
SCNN1AENSG00000111319.81244.80610572.457901.1206013.9438012.62050HepG2SUPV3L1
SCNN1AENSG00000111319.8747.37280963.46970-0.366402.533401.83530HepG2TARDBP
SCNN1AENSG00000111319.8577.383401603.66810-1.4738011.906709.88440HepG2TBRG4
SCNN1AENSG00000111319.8687.20330383.681600.840707.424605.93070HepG2TFIP11
SCNN1AENSG00000111319.81861.39960905.837801.0390025.2944022.81630HepG2TIA1
SCNN1AENSG00000111319.8981.26140661.200200.569508.944708.02040HepG2TRIM56
SCNN1AENSG00000111319.8702.86560890.51210-0.341402.593201.74990HepG2TUFM
SCNN1AENSG00000111319.8994.28380453.235801.133303.746602.58910HepG2U2AF2
SCNN1AENSG00000111319.81249.01860942.568800.406002.602601.79110HepG2UBE2L3
SCNN1AENSG00000111319.8161.93310338.14960-1.062308.756507.40170HepG2UCHL5
SCNN1AENSG00000111319.81631.96340713.241101.1940044.5543042.47640HepG2UPF1
SCNN1AENSG00000111319.8263.57520524.12340-0.991706.902105.27390HepG2UPF2
SCNN1AENSG00000111319.8944.28960733.098800.365103.301402.16770HepG2UTP18
SCNN1AENSG00000111319.8533.62980688.60350-0.367802.929202.31620HepG2UTP3
SCNN1AENSG00000111319.81902.615101131.031900.750206.752905.04840HepG2XPO5
SCNN1AENSG00000111319.8951.77150646.129700.558703.249001.87190HepG2XRCC5
SCNN1AENSG00000111319.8145.09240563.52280-1.9575029.2548027.04900HepG2XRN2
SCNN1AENSG00000111319.8605.45950909.47650-0.587009.152508.05000HepG2ZC3H8
SCNN1AENSG00000111319.81135.70390784.426200.533805.866005.14780HepG2ZNF622
SCNN1AENSG00000111319.8430.02670656.46970-0.610303.802302.26490HepG2ZRANB2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for SCNN1A is not available on ENCORE database.





3 RBPs can affect the splicing of SCNN1A :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SESCNN1AENSG00000111319.8chr12-645832964583876458115645817164584926458571-0.604000.000000.00000excludedHepG2U2AF1
SESCNN1AENSG00000111319.8chr12-645832964583876458115645817164584926458571-0.790000.000000.00000excludedHepG2U2AF2
SESCNN1AENSG00000111319.8chr12-645832964583876458115645817164584926458571-0.192000.000390.02169excludedHepG2SF3B4
A5SSSCNN1AENSG00000111319.8chr12-645832964585326458492645853264581156458171-0.848000.000000.00000shorterHepG2U2AF2

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for SCNN1A is not avaliable on ENCORE database.