PTPN7

General Information

Gene Name       : PTPN7
Gene ID             : ENSG00000143851.15
Essential Gene : No

Functions

Localization

Domains (AlphaFold: PTPN7)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PTPN7ENSG00000143851.1546.5369.5458.04ENCSR000AEF
HepG2PTPN7ENSG00000143851.150.000.000.00ENCSR985KAT
K562PTPN7ENSG00000143851.15136.6096.76116.68ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PTPN7 is not avaliable on ENCORE database.



Proteins bound to RNA
  • PTPN7 RNA is bound by 13 proteins.  







eCLIP assay for PTPN7 is not avaliable on ENCORE database.





13 proteins are bound to PTPN7 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr1202117109202117194-3'-UTR,intron-Distal4.4474112.76076K562UPF1
chr1202123313202123444-3'-UTR,CDS,intron-Distal,intron-Proximal3.094595.92720K562ZNF622
chr1202116549202116575-3'-UTR,intron-Distal4.705054.31428K562YBX3
chr1202116325202116441-3'-UTR,intron-Distal4.655886.19943K562RBM15
chr1202116286202116310-3'-UTR,intron-Distal4.450683.87930K562UPF1
chr1202117023202117109-3'-UTR,intron-Distal3.757709.74385K562UPF1
chr1202119432202119464-3'-UTR,CDS,intron-Distal,intron-Proximal4.086453.70678K562BUD13
chr1202123398202123447-3'-UTR,CDS,intron-Distal3.135623.70975K562UCHL5
chr1202117153202117202-3'-UTR,intron-Distal4.364343.46958K562YBX3
chr1202121576202121673-3'-UTR,CDS,intron-Distal,intron-Proximal4.653076.39176K562AQR
chr1202119428202119498-3'-UTR,CDS,intron-Distal,intron-Proximal5.024005.50697K562UCHL5
chr1202122777202122855-3'-UTR,CDS,intron-Distal,intron-Proximal3.419625.66421K562PRPF8
chr1202116855202116929-3'-UTR,intron-Distal4.056564.94406K562YBX3
chr1202117275202117318-3'-UTR,intron-Distal,intron-Proximal3.084373.80905K562UPF1
chr1202117214202117260-3'-UTR,intron-Distal,intron-Proximal4.337857.83400K562UPF1
chr1202126865202126947-5'-UTR,CDS,intron-Distal,intron-Proximal4.122736.09767K562UCHL5
chr1202128756202128841-5'-UTR,intron-Distal4.7034541.76886K562PTBP1
chr1202129727202129808-5'-UTR,CDS,intron-Distal,intron-Proximal3.349135.31818K562GTF2F1
chr1202128860202128919-5'-UTR,intron-Distal4.0229617.15704K562PTBP1
chr1202130285202130334-5'-UTR,intron-Distal4.788069.12458K562XRN2
chr1202124660202124684-5'-UTR,CDS,intron-Distal,intron-Proximal3.439283.12941K562UCHL5
chr1202129703202129768-5'-UTR,CDS,intron-Distal,intron-Proximal4.136025.74136K562DDX24
chr1202124689202124738-5'-UTR,CDS,intron-Distal,intron-Proximal3.420635.23038K562ZNF622
chr1202128709202128744-5'-UTR,intron-Distal4.144336.12189K562PTBP1
chr1202128293202128346-intron-Distal,intron-Proximal3.245664.91549K562PRPF8
chr1202122844202122853-intron-Distal,intron-Proximal4.823593.32531K562AQR
chr1202129515202129578-intron-Distal3.710093.22046K562AKAP8L
chr1202122789202122821-intron-Distal,intron-Proximal4.284594.52312K562AQR
chr1202128346202128405-intron-Distal,intron-Proximal3.788116.43995K562PRPF8
chr1202126822202126845-intron-Distal,intron-Proximal4.114143.49003K562PRPF8
chr1202128310202128403-intron-Distal,intron-Proximal5.312118.03507K562AQR
chr1202124539202124593-intron-Distal,intron-Proximal3.908843.02324K562XRN2
chr1202122821202122844-intron-Distal,intron-Proximal4.992114.09264K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PTPN7 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PTPN7 is not available on ENCORE database.

  • 104 RBPs can affect the levels of PTPN7.  








The Knockdown/knockout RNA-Seq assay for PTPN7 is not available on ENCORE database.





104 RBPs can affect the gene expression of PTPN7 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PTPN7ENSG00000143851.1121.136701.557203.762604.515203.67500HepG2AUH
PTPN7ENSG00000143851.112310.406501584.653300.543904.023502.57020K562AARS
PTPN7ENSG00000143851.11610.480201501.45470-1.2983013.6751012.51590K562AGGF1
PTPN7ENSG00000143851.11977.257501242.91010-0.346903.934202.10470K562AKAP1
PTPN7ENSG00000143851.111001.525801649.65390-0.720005.990404.40650K562AKAP8
PTPN7ENSG00000143851.11964.517901562.27810-0.695806.220205.21310K562AKAP8L
PTPN7ENSG00000143851.111505.507004579.79670-1.6050013.6042012.44380K562AQR
PTPN7ENSG00000143851.11871.540901639.10450-0.911308.321506.60820K562ATP5C1
PTPN7ENSG00000143851.112187.017902812.68010-0.363002.687101.74000K562BCLAF1
PTPN7ENSG00000143851.111732.699302429.30330-0.487505.050703.85890K562BOP1
PTPN7ENSG00000143851.111738.642702537.46870-0.545408.671806.06520K562CEBPZ
PTPN7ENSG00000143851.111615.484902919.09720-0.853606.645304.95350K562CNOT7
PTPN7ENSG00000143851.111809.263402582.99140-0.513607.722006.40220K562CPSF6
PTPN7ENSG00000143851.111252.840402075.81210-0.728504.219601.88920K562CPSF7
PTPN7ENSG00000143851.111476.911402133.83800-0.530904.494503.10450K562CSTF2
PTPN7ENSG00000143851.114603.492606709.15320-0.543404.506103.25200K562CELF1
PTPN7ENSG00000143851.111981.102802916.39010-0.5579011.992709.48520K562DDX21
PTPN7ENSG00000143851.111838.493802465.64700-0.423403.324801.85990K562DDX27
PTPN7ENSG00000143851.11977.048501259.33690-0.366203.410102.23820K562DDX3X
PTPN7ENSG00000143851.111726.862603971.58030-1.2016016.5065015.03590K562DDX47
PTPN7ENSG00000143851.111013.504701276.78470-0.333203.506001.98580K562DDX6
PTPN7ENSG00000143851.111156.572401681.45930-0.539903.373602.39380K562DKC1
PTPN7ENSG00000143851.115324.090304036.832000.399202.518601.82660K562EIF2S2
PTPN7ENSG00000143851.111125.191701975.25010-0.811906.196004.64690K562EIF3A
PTPN7ENSG00000143851.111993.784001503.240200.407305.050603.98950K562EIF3G
PTPN7ENSG00000143851.111429.872001148.429300.316103.039501.67090K562EWSR1
PTPN7ENSG00000143851.111767.217002986.55700-0.7570015.3802012.51090K562EXOSC5
PTPN7ENSG00000143851.111131.822201505.17450-0.411303.093101.88860K562FKBP4
PTPN7ENSG00000143851.111644.499002628.23910-0.676409.835308.17100K562FMR1
PTPN7ENSG00000143851.111559.149502227.71600-0.514804.978303.71110K562FTO
PTPN7ENSG00000143851.111730.863601368.236900.339104.146503.42770K562FXR1
PTPN7ENSG00000143851.11553.69050845.09640-0.610001.893601.32100K562G3BP2
PTPN7ENSG00000143851.112340.440203145.20330-0.426405.300703.74950K562GLRX3
PTPN7ENSG00000143851.111574.206502466.07710-0.647609.794208.28880K562GPKOW
PTPN7ENSG00000143851.112170.820805378.65220-1.3090010.873309.34540K562GRSF1
PTPN7ENSG00000143851.111130.359302581.10730-1.1912024.7895022.13470K562HNRNPA1
PTPN7ENSG00000143851.11571.093601526.30830-1.4182011.340808.30050K562HNRNPA2B1
PTPN7ENSG00000143851.111942.400902732.07190-0.492202.911901.30320K562HNRNPAB
PTPN7ENSG00000143851.11965.583901734.21010-0.8448015.1511013.83960K562HNRNPC
PTPN7ENSG00000143851.112161.095801548.528000.480804.935603.35140K562HNRNPF
PTPN7ENSG00000143851.112426.997003142.48780-0.372704.222001.88890K562HNRNPH1
PTPN7ENSG00000143851.112490.458101620.790500.619604.316602.73510K562HNRNPK
PTPN7ENSG00000143851.112707.217303588.92010-0.406703.013201.90590K562HNRNPL
PTPN7ENSG00000143851.111481.819302572.83880-0.796002.523001.63640K562HNRNPM
PTPN7ENSG00000143851.112052.104102858.53580-0.478208.304706.76670K562HNRNPU
PTPN7ENSG00000143851.111478.166901960.69390-0.407603.415801.76310K562KHDRBS1
PTPN7ENSG00000143851.11925.633301658.15540-0.841107.208405.72550K562KIF1C
PTPN7ENSG00000143851.111126.358702105.83780-0.9027010.072408.16750K562KRR1
PTPN7ENSG00000143851.111096.873501587.11040-0.533003.001801.87100K562MAK16
PTPN7ENSG00000143851.111704.024602407.18500-0.498406.385305.02820K562METAP2
PTPN7ENSG00000143851.111318.914903306.75120-1.3261073.8496070.84200K562MTPAP
PTPN7ENSG00000143851.11732.052501301.97520-0.830706.068604.56930K562NAA15
PTPN7ENSG00000143851.111900.865403674.20930-0.9508053.5032050.93400K562NSUN2
PTPN7ENSG00000143851.11485.673601335.23480-1.4590011.662709.13620K562PABPN1
PTPN7ENSG00000143851.112097.248701517.601300.466602.690901.72620K562PCBP2
PTPN7ENSG00000143851.11815.260303798.88620-2.2202074.4325070.91860K562PCBP3
PTPN7ENSG00000143851.111490.219302196.06930-0.559405.668303.02860K562PES1
PTPN7ENSG00000143851.113381.451105608.02820-0.729906.068404.05660K562PNPT1
PTPN7ENSG00000143851.11663.085802913.85310-2.13570103.3105099.91150K562POLR2G
PTPN7ENSG00000143851.111153.895202255.44610-0.9669017.1240015.22580K562PRPF8
PTPN7ENSG00000143851.112095.745501554.866600.430604.413403.23040K562PSIP1
PTPN7ENSG00000143851.112755.829701657.585700.733305.368804.46990K562PTBP1
PTPN7ENSG00000143851.113840.758105955.16820-0.632804.446403.41820K562PUF60
PTPN7ENSG00000143851.11626.043101549.73480-1.3077013.3395012.19200K562PUS1
PTPN7ENSG00000143851.11742.461401509.66520-1.023809.969508.87110K562RBM15
PTPN7ENSG00000143851.113252.563405102.22900-0.649604.265402.26450K562RBM17
PTPN7ENSG00000143851.112719.487201588.539600.775505.326104.11440K562RBM22
PTPN7ENSG00000143851.11580.72420801.64150-0.465103.876502.25960K562RBM25
PTPN7ENSG00000143851.112454.489301418.448200.7910016.5808014.18550K562RCC2
PTPN7ENSG00000143851.112777.710801671.891200.732302.308301.32920K562NELFE
PTPN7ENSG00000143851.111117.445102297.35390-1.0398015.5413013.57950K562RPS19
PTPN7ENSG00000143851.111313.20900601.825601.125604.821003.45270K562RPS3
PTPN7ENSG00000143851.111238.866602306.02180-0.896409.792507.40380K562RRP9
PTPN7ENSG00000143851.111106.986102596.38320-1.2299033.5282030.68900K562SAFB
PTPN7ENSG00000143851.111649.863002684.32800-0.7022010.618807.96760K562SDAD1
PTPN7ENSG00000143851.112313.020903625.34080-0.6483017.7163015.80490K562SF3A3
PTPN7ENSG00000143851.111528.909802345.48730-0.617406.516104.98930K562SF3B1
PTPN7ENSG00000143851.111322.886802138.83840-0.693109.592107.36180K562SLBP
PTPN7ENSG00000143851.11903.535401402.33140-0.634202.634101.44800K562SNRNP200
PTPN7ENSG00000143851.112672.558101625.169000.717506.034604.99910K562SRSF1
PTPN7ENSG00000143851.11753.55340581.027700.375002.546001.54290K562SRSF4
PTPN7ENSG00000143851.111643.832502602.38360-0.6628015.7378012.91460K562SRSF7
PTPN7ENSG00000143851.112282.748803316.64290-0.539009.179506.45650K562SRSF9
PTPN7ENSG00000143851.111037.916001550.57180-0.579105.949703.94320K562SSB
PTPN7ENSG00000143851.111525.537302602.50400-0.770604.264302.22760K562STIP1
PTPN7ENSG00000143851.113822.087405196.05650-0.443103.206501.59500K562SUCLG1
PTPN7ENSG00000143851.11679.292601677.49750-1.304209.104105.99250K562SUPT6H
PTPN7ENSG00000143851.111209.976402183.63090-0.8518011.473109.36430K562SUPV3L1
PTPN7ENSG00000143851.111265.378702922.70130-1.2077039.2211036.59630K562SYNCRIP
PTPN7ENSG00000143851.112589.932601644.384200.655305.615604.58710K562TARDBP
PTPN7ENSG00000143851.111226.121001588.63440-0.373702.583101.67560K562TRIM56
PTPN7ENSG00000143851.111991.841002761.85470-0.471504.599502.29770K562TRNAU1AP
PTPN7ENSG00000143851.111353.46510819.240700.724207.521505.55850K562U2AF1
PTPN7ENSG00000143851.111425.31340846.075200.7523013.2780011.50400K562U2AF2
PTPN7ENSG00000143851.118393.325106712.992800.322204.372502.60720K562UBE2L3
PTPN7ENSG00000143851.111415.141402311.16860-0.707709.431307.48990K562UCHL5
PTPN7ENSG00000143851.112731.264203895.83310-0.512407.585106.46880K562UPF1
PTPN7ENSG00000143851.11885.911701570.88160-0.826305.089403.14910K562UTP18
PTPN7ENSG00000143851.111522.464303333.55580-1.1307027.0661024.52650K562WDR3
PTPN7ENSG00000143851.111994.695803466.41210-0.7973031.7237029.42120K562WDR43
PTPN7ENSG00000143851.113511.372705424.56360-0.627504.459502.80920K562WRN
PTPN7ENSG00000143851.111676.719802353.51710-0.489204.945203.15270K562XRN2
PTPN7ENSG00000143851.111028.840701650.42030-0.681802.985901.32570K562YTHDC2
PTPN7ENSG00000143851.112465.566503107.62620-0.333903.395201.34810K562ZNF800
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PTPN7 is not available on ENCORE database.





15 RBPs can affect the splicing of PTPN7 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPTPN7ENSG00000143851.11chr1-2021183622021184922021161402021178272021194382021195520.173000.000210.09671includedK562TAF15
SEPTPN7ENSG00000143851.11chr1-202118362202118500202116140202117827202119438202119552-0.092000.000000.00012excludedK562SRSF1
SEPTPN7ENSG00000143851.11chr1-202128408202128582202127245202127429202129672202130709-0.055000.001710.09384excludedK562HNRNPL
SEPTPN7ENSG00000143851.11chr1-2021183622021185002021161402021178272021194382021195520.150000.000450.07488includedK562FXR2
SEPTPN7ENSG00000143851.11chr1-202127245202127429202126866202126951202128408202128582-0.201000.000050.00350excludedK562TARDBP
SEPTPN7ENSG00000143851.11chr1-202128408202128582202127245202127429202129672202130709-0.107000.000370.06501excludedK562NPM1
A3SSPTPN7ENSG00000143851.11chr1-2021268662021270662021268662021269512021272452021274290.397000.000000.00000longerK562U2AF2
A3SSPTPN7ENSG00000143851.11chr1-2021228522021229782021228522021229632021233132021234510.102000.003130.09132longerK562U2AF2
A3SSPTPN7ENSG00000143851.11chr1-2021268662021270662021268662021269512021272452021274290.276000.000040.00425longerK562SF3B4
A3SSPTPN7ENSG00000143851.11chr1-202126866202127066202126866202126951202127245202127429-0.154000.000000.00361shorterK562DROSHA
A3SSPTPN7ENSG00000143851.11chr1-202126866202127066202126866202126951202127245202127429-0.160000.000060.02220shorterK562HNRNPUL1
A3SSPTPN7ENSG00000143851.11chr1-2021284082021286052021284082021285822021296722021297330.098000.003920.02333longerK562AQR
A3SSPTPN7ENSG00000143851.11chr1-202126866202127066202126866202126951202127245202127429-0.158000.000010.01847shorterK562LARP4
A3SSPTPN7ENSG00000143851.11chr1-2021268662021270662021268662021269512021272452021274290.144000.000000.00001longerK562SF3B1
A3SSPTPN7ENSG00000143851.11chr1-2021268662021270662021268662021269512021272452021274290.327000.000000.00045longerK562U2AF1
A3SSPTPN7ENSG00000143851.11chr1-2021268662021270662021268662021269512021272452021274290.161000.000020.01172longerK562HNRNPK
A3SSPTPN7ENSG00000143851.11chr1-202127245202127448202127245202127429202128408202128582-0.121000.000520.04784shorterK562SRSF1
MXEPTPN7ENSG00000143851.11chr1-2021183622021185002021194382021195522021161402021178272021216692021218270.063000.000490.011081includedK562SRSF1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PTPN7 is not avaliable on ENCORE database.