PRKAA1

General Information

Gene Name       : PRKAA1
Gene ID             : ENSG00000132356.11
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: PRKAA1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PRKAA1ENSG00000132356.1142.6337.8040.22ENCSR000AEF
HepG2PRKAA1ENSG00000132356.1121.4038.0029.70ENCSR985KAT
K562PRKAA1ENSG00000132356.1155.2550.5752.91ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PRKAA1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • PRKAA1 RNA is bound by 21 proteins.  







eCLIP assay for PRKAA1 is not avaliable on ENCORE database.





21 proteins are bound to PRKAA1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr54076247140762612-3'-UTR,intron-Distal4.036827.17500HepG2FUBP3
chr54076146540761558-3'-UTR,intron-Distal3.297804.56889HepG2FUBP3
chr54076036340760458-3'-UTR,intron-Distal4.377326.38228HepG2FUBP3
chr54076022040760270-3'-UTR,intron-Distal3.469533.68079HepG2FUBP3
chr54076049140760568-3'-UTR,intron-Distal3.143943.51696K562KHSRP
chr54076034540760409-3'-UTR,intron-Distal3.970033.25538K562KHSRP
chr54076102840761080-3'-UTR,intron-Distal3.691293.25175K562YBX3
chr54076756840767689-CDS,intron-Distal,intron-Proximal3.308183.77614HepG2G3BP1
chr54077750340777549-CDS,intron-Distal,intron-Proximal4.781205.33214K562PRPF8
chr54077763240777682-CDS,intron-Distal4.796434.69889HepG2GRWD1
chr54076763340767734-CDS,intron-Distal3.3044910.67070HepG2BCLAF1
chr54076485440764907-CDS,intron-Distal,intron-Proximal4.509338.15024HepG2BCLAF1
chr54077556840775663-CDS,intron-Distal,intron-Proximal4.0322015.14911K562SF3B4
chr54077752140777632-CDS,intron-Distal,intron-Proximal3.8524710.16718HepG2GRWD1
chr54077753040777618-CDS,intron-Distal,intron-Proximal3.665309.83277HepG2BCLAF1
chr54076505940765083-CDS,intron-Distal4.193855.38772K562RBM15
chr54076757140767630-CDS,intron-Distal,intron-Proximal4.305053.81597K562RBM15
chr54076454640764622-CDS,intron-Distal,intron-Proximal3.442173.54718K562PRPF8
chr54076513440765276-CDS,intron-Distal4.4201816.40391HepG2BCLAF1
chr54076462240764637-CDS,intron-Distal3.008143.55800HepG2BCLAF1
chr54076756840767633-CDS,intron-Distal,intron-Proximal4.4190211.55759HepG2BCLAF1
chr54076465240764733-CDS,intron-Distal3.263474.25541HepG2GRWD1
chr54077182440771901-CDS,intron-Distal5.9539613.95734HepG2BCLAF1
chr54079811840798197-CDS,intron-Distal4.255578.11807HepG2PRPF8
chr54076514040765304-CDS,intron-Distal3.038536.72633K562RBM15
chr54076503040765059-CDS,intron-Distal,intron-Proximal3.290283.78791K562RBM15
chr54076292640762985-CDS,intron-Distal3.756573.14999HepG2GRWD1
chr54076773440767793-CDS,intron-Distal,intron-Proximal3.530347.01246HepG2BCLAF1
chr54077601340776054-intron-Distal4.724574.40618K562PTBP1
chr54077316740773259-intron-Distal3.331496.59733K562KHSRP
chr54077357240773654-intron-Distal3.189048.43260K562KHSRP
chr54078049740780604-intron-Distal4.730426.94732K562KHSRP
chr54077647340776564-intron-Distal3.050274.09021HepG2HNRNPL
chr54079786840797968-intron-Distal4.211804.75311K562CSTF2T
chr54077737940777459-intron-Distal,intron-Proximal3.9278410.58235HepG2U2AF2
chr54077665740776685-intron-Distal4.122294.36036HepG2SUGP2
chr54079531240795377-intron-Distal4.319244.62179HepG2HNRNPK
chr54078511540785183-intron-Distal4.070893.60944K562TARDBP
chr54077580340775823-intron-Distal4.450314.86548HepG2SUGP2
chr54079750940797621-intron-Distal3.140973.36616K562NONO
chr54079778340797876-intron-Distal3.868085.72412HepG2FAM120A
chr54078291440783033-intron-Distal3.139625.98045K562KHSRP
chr54077578540775828-intron-Distal3.516613.55754HepG2U2AF2
chr54078454840784661-intron-Distal3.149293.07751K562KHSRP
chr54079777540797907-intron-Distal4.393934.35952HepG2PRPF4
chr54077167940771781-intron-Distal,intron-Proximal4.853736.80771K562PRPF8
chr54077623840776355-intron-Distal3.1231613.86816HepG2SUGP2
chr54077466640774714-intron-Distal3.428194.97118HepG2U2AF2
chr54079779440797894-intron-Distal4.138553.57329K562XRN2
chr54077584440775913-intron-Distal3.223467.32436HepG2SUGP2
chr54079791240797966-intron-Distal3.421644.59965HepG2PRPF4
chr54079591440795994-intron-Distal3.537524.09242HepG2QKI
chr54076551340765603-intron-Distal3.157903.05068HepG2U2AF2
chr54079777340797875-intron-Distal3.391416.58651HepG2CSTF2T
chr54078267540782807-intron-Distal3.151785.83938K562KHSRP
chr54077350940773535-intron-Distal4.359093.45799HepG2U2AF2
chr54077626240776356-intron-Distal3.836859.01453K562PTBP1
chr54077587740775923-intron-Distal3.579373.95921HepG2U2AF2
chr54079791440797968-intron-Distal4.242444.10339HepG2CSTF2T
chr54077393640774020-intron-Distal3.040656.35394HepG2SUGP2
chr54077674440776850-intron-Distal3.030126.29446HepG2SUGP2
chr54078649940786550-intron-Distal3.826173.94088HepG2QKI
chr54076447840764583-intron-Distal,intron-Proximal3.587283.64762HepG2QKI
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PRKAA1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PRKAA1 is not available on ENCORE database.

  • 98 RBPs can affect the levels of PRKAA1.  








The Knockdown/knockout RNA-Seq assay for PRKAA1 is not available on ENCORE database.





98 RBPs can affect the gene expression of PRKAA1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PRKAA1ENSG00000132356.71565.068201263.746000.308402.382701.38440HepG2AATF
PRKAA1ENSG00000132356.71758.982102623.46380-0.576706.240404.88990HepG2ABCF1
PRKAA1ENSG00000132356.71218.840801710.57300-0.489004.724403.46400HepG2ADAR
PRKAA1ENSG00000132356.72029.741402597.23920-0.355702.317101.82590HepG2AKAP1
PRKAA1ENSG00000132356.72082.616302460.96460-0.240802.685402.00850HepG2AUH
PRKAA1ENSG00000132356.7906.139601411.30890-0.639202.969101.99470HepG2BCCIP
PRKAA1ENSG00000132356.73340.275502287.234200.546309.339908.04630HepG2CALR
PRKAA1ENSG00000132356.71339.868902041.69280-0.607706.809805.63140HepG2CIRBP
PRKAA1ENSG00000132356.71205.587101754.18630-0.541109.022007.21040HepG2YBX3
PRKAA1ENSG00000132356.7599.86850872.02200-0.539702.568401.52760HepG2CSTF2
PRKAA1ENSG00000132356.72505.246202153.122200.218402.164701.58510HepG2CELF1
PRKAA1ENSG00000132356.71845.768602315.37160-0.327006.581705.50830HepG2DAZAP1
PRKAA1ENSG00000132356.71147.800901514.81110-0.400305.305804.19960HepG2DDX19B
PRKAA1ENSG00000132356.71389.999601756.60410-0.337703.980402.60990HepG2DDX1
PRKAA1ENSG00000132356.7991.375601394.26650-0.492005.109904.21690HepG2DDX21
PRKAA1ENSG00000132356.7583.792101298.49940-1.153306.748104.82840HepG2DDX27
PRKAA1ENSG00000132356.74335.429302818.127000.621302.355301.45380HepG2DDX59
PRKAA1ENSG00000132356.71652.381302137.22150-0.371202.454001.86970HepG2DDX6
PRKAA1ENSG00000132356.71267.149401566.96520-0.306403.638302.88050HepG2DKC1
PRKAA1ENSG00000132356.71073.616001707.28890-0.6692012.0930010.83260HepG2DNAJC2
PRKAA1ENSG00000132356.71872.755101283.935200.544504.186202.80990HepG2AGO1
PRKAA1ENSG00000132356.71060.523201316.67540-0.312102.670101.60780HepG2EIF3G
PRKAA1ENSG00000132356.71693.752202270.49990-0.422803.007802.34150HepG2EIF4A3
PRKAA1ENSG00000132356.72070.439402825.54960-0.448608.695507.73150HepG2ETF1
PRKAA1ENSG00000132356.7913.322301284.44430-0.491905.886404.14350HepG2FAM120A
PRKAA1ENSG00000132356.73696.451402485.789400.572302.203101.30530HepG2FTO
PRKAA1ENSG00000132356.71782.844701311.495700.442904.885903.85690HepG2FUBP3
PRKAA1ENSG00000132356.71703.977602290.87020-0.427003.716702.92420HepG2FXR1
PRKAA1ENSG00000132356.7943.004701279.59180-0.440303.804202.73770HepG2GEMIN5
PRKAA1ENSG00000132356.72150.940702813.41770-0.387401.929601.38880HepG2GPKOW
PRKAA1ENSG00000132356.72018.136801563.743300.367905.873604.51020HepG2HDGF
PRKAA1ENSG00000132356.71081.446201738.93950-0.6852010.049708.93180HepG2HNRNPA1
PRKAA1ENSG00000132356.71755.859402151.89600-0.293402.187101.56080HepG2HNRNPK
PRKAA1ENSG00000132356.71442.203502109.19810-0.5484015.2186013.75160HepG2HNRNPL
PRKAA1ENSG00000132356.73780.728902684.876700.493703.603002.89450HepG2HNRNPLL
PRKAA1ENSG00000132356.72197.155201921.479300.193302.102601.56640HepG2HNRNPU
PRKAA1ENSG00000132356.71590.944502160.11370-0.441203.986903.19060HepG2IGF2BP2
PRKAA1ENSG00000132356.71642.997401962.72400-0.256503.937703.07830HepG2ILF2
PRKAA1ENSG00000132356.72452.253103390.10180-0.467203.509302.57250HepG2LARP4
PRKAA1ENSG00000132356.71669.740402291.67010-0.456803.983903.19710HepG2MAGOH
PRKAA1ENSG00000132356.7954.249902304.49130-1.2720022.0869020.44130HepG2MATR3
PRKAA1ENSG00000132356.72194.274501800.520200.285202.457301.31540HepG2NAA15
PRKAA1ENSG00000132356.71861.039502358.77090-0.341902.398001.80570HepG2NCBP2
PRKAA1ENSG00000132356.71725.139502295.90510-0.412306.000404.87870HepG2NOL12
PRKAA1ENSG00000132356.71365.420002004.31360-0.5538011.7373010.62590HepG2PCBP1
PRKAA1ENSG00000132356.71838.777102191.57660-0.253202.126701.59460HepG2PUF60
PRKAA1ENSG00000132356.73086.398702326.378400.4077010.273009.28150HepG2PUM1
PRKAA1ENSG00000132356.72991.931202208.736100.437807.012806.08380HepG2QKI
PRKAA1ENSG00000132356.73035.352801759.252700.786805.558204.58030HepG2RAVER1
PRKAA1ENSG00000132356.73080.951602646.375000.219302.199101.42420HepG2RBM15
PRKAA1ENSG00000132356.72006.465402361.62980-0.235102.481001.98360HepG2RBM22
PRKAA1ENSG00000132356.73346.204202004.611300.7391015.0127013.50590HepG2RBM25
PRKAA1ENSG00000132356.71469.267302269.74210-0.6274014.5956013.53740HepG2NELFE
PRKAA1ENSG00000132356.71698.842902114.03370-0.315404.361403.61090HepG2RECQL
PRKAA1ENSG00000132356.71010.331401398.40720-0.469005.027704.22660HepG2RPS19
PRKAA1ENSG00000132356.71089.216101693.90380-0.637102.380101.63330HepG2RPS2
PRKAA1ENSG00000132356.71449.561901059.372900.452303.929403.01210HepG2RRP9
PRKAA1ENSG00000132356.71459.858401711.15030-0.229102.688002.05040HepG2SAFB2
PRKAA1ENSG00000132356.71808.493202657.62280-0.555303.860303.03850HepG2SF3B1
PRKAA1ENSG00000132356.71765.186802123.30670-0.266503.228502.59620HepG2SF3B4
PRKAA1ENSG00000132356.71443.715702101.22230-0.5414014.3036012.92790HepG2SLBP
PRKAA1ENSG00000132356.71581.169301995.47020-0.335706.249205.34290HepG2SMN1
PRKAA1ENSG00000132356.74895.984402957.026500.727406.240205.05840HepG2SNRNP70
PRKAA1ENSG00000132356.71881.663802667.36180-0.5034012.1956011.34230HepG2SRFBP1
PRKAA1ENSG00000132356.71207.867302216.31010-0.8757028.7275027.55770HepG2SRSF1
PRKAA1ENSG00000132356.74075.154202859.255200.511104.268302.99720HepG2SRSF3
PRKAA1ENSG00000132356.72130.892101803.118700.240903.151202.57000HepG2SRSF9
PRKAA1ENSG00000132356.71638.552202315.88040-0.4991011.1265010.23180HepG2SSB
PRKAA1ENSG00000132356.72450.008201643.964900.575503.879102.44640HepG2SUB1
PRKAA1ENSG00000132356.72350.364401830.459100.360604.201703.17980HepG2TIA1
PRKAA1ENSG00000132356.7903.101701866.99990-1.0478026.5123025.25930HepG2TIAL1
PRKAA1ENSG00000132356.71482.015001883.77140-0.346105.174004.45190HepG2TRIM56
PRKAA1ENSG00000132356.7584.22530816.13960-0.482302.194901.51790HepG2UCHL5
PRKAA1ENSG00000132356.7644.009201265.34090-0.974403.570502.42040HepG2UPF2
PRKAA1ENSG00000132356.7538.149401359.83220-1.337308.726507.45600HepG2XRN2
PRKAA1ENSG00000132356.71035.425801733.50410-0.7435021.7052020.14820HepG2ZC3H8
PRKAA1ENSG00000132356.73024.989302337.694800.371709.210708.36190HepG2ZNF622
PRKAA1ENSG00000132356.71958.397101582.327300.307502.555001.42640K562AARS
PRKAA1ENSG00000132356.71947.322702429.71850-0.319302.774902.18620K562AQR
PRKAA1ENSG00000132356.71239.356401509.76570-0.284703.298902.24820K562BCLAF1
PRKAA1ENSG00000132356.72721.510403248.15650-0.255203.133801.94970K562CPEB4
PRKAA1ENSG00000132356.72406.937803092.53070-0.361604.399403.41320K562CPSF6
PRKAA1ENSG00000132356.74965.203704177.551600.249103.099802.06870K562CELF1
PRKAA1ENSG00000132356.7840.084201323.82510-0.6561012.6720010.03940K562DDX27
PRKAA1ENSG00000132356.71750.107101295.664400.433703.043401.69640K562EEF2
PRKAA1ENSG00000132356.71633.633201947.75590-0.253702.479201.79180K562EIF2S2
PRKAA1ENSG00000132356.71950.911202843.62680-0.543602.677201.84290K562FIP1L1
PRKAA1ENSG00000132356.71895.941701502.963000.335002.372801.34010K562FKBP4
PRKAA1ENSG00000132356.72392.539603146.74510-0.395303.952802.92740K562FMR1
PRKAA1ENSG00000132356.72344.581701592.832600.557604.351303.42090K562G3BP2
PRKAA1ENSG00000132356.72241.883502952.53620-0.397202.953502.13390K562GPKOW
PRKAA1ENSG00000132356.71729.536802595.74340-0.585808.129006.82120K562GRSF1
PRKAA1ENSG00000132356.71176.525101731.66780-0.557607.220006.29970K562HNRNPC
PRKAA1ENSG00000132356.71241.777701546.25640-0.316402.646101.53290K562HNRNPF
PRKAA1ENSG00000132356.72015.716303037.52980-0.591609.481107.43190K562HNRNPL
PRKAA1ENSG00000132356.72629.165503855.68100-0.552402.842402.03630K562HSPD1
PRKAA1ENSG00000132356.71478.409901914.09400-0.372603.258202.24830K562MATR3
PRKAA1ENSG00000132356.71548.275002882.03420-0.8964019.1206016.75740K562METAP2
PRKAA1ENSG00000132356.72777.956301976.473400.491003.591902.55440K562NAA15
PRKAA1ENSG00000132356.71993.390403227.74280-0.695304.254003.20640K562PPIG
PRKAA1ENSG00000132356.73019.272303707.57180-0.296302.346901.59570K562PUF60
PRKAA1ENSG00000132356.74928.541303943.055600.321704.586503.18600K562PUM1
PRKAA1ENSG00000132356.73748.975302352.333000.672309.927508.94580K562PUS1
PRKAA1ENSG00000132356.72789.962002291.835000.283603.203702.57290K562RBM15
PRKAA1ENSG00000132356.72117.948002808.22020-0.407003.253702.19670K562SF3B1
PRKAA1ENSG00000132356.71361.057001656.16900-0.283102.617101.78710K562SF3B4
PRKAA1ENSG00000132356.71360.878201826.52350-0.424603.706902.89370K562SRSF1
PRKAA1ENSG00000132356.71228.942501501.88840-0.289402.250601.31930K562SRSF4
PRKAA1ENSG00000132356.71167.970201493.34910-0.354502.432901.55870K562TIAL1
PRKAA1ENSG00000132356.71899.389801594.510700.252302.207601.49020K562U2AF2
PRKAA1ENSG00000132356.72734.953102276.281500.264703.428502.49420K562WDR43
PRKAA1ENSG00000132356.7969.870101271.22100-0.390402.742201.54380K562XRN2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PRKAA1 is not available on ENCORE database.





16 RBPs can affect the splicing of PRKAA1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPRKAA1ENSG00000132356.7chr5-407695174076960540767567407677924077182040771965-0.229000.000160.00471excludedK562SF3B4
SEPRKAA1ENSG00000132356.7chr5-407695174076960540767567407677924077182040771965-0.081000.003270.05448excludedHepG2U2AF1
SEPRKAA1ENSG00000132356.7chr5-4077502940775074407718204077196540775511407756050.206000.000650.00969includedHepG2U2AF2
SEPRKAA1ENSG00000132356.7chr5-407695174076960540767567407677924077182040771984-0.290000.000000.00000excludedK562AQR
SEPRKAA1ENSG00000132356.7chr5-4076951740769605407675674076779240771820407719650.073000.001240.09389includedHepG2SRSF7
SEPRKAA1ENSG00000132356.7chr5-407695174076960540767567407677924077182040771965-0.101000.000630.01162excludedK562PUS1
SEPRKAA1ENSG00000132356.7chr5-4077502940775074407718204077196540775511407756050.161000.001720.09484includedHepG2IGF2BP3
SEPRKAA1ENSG00000132356.7chr5-407695174076960540767567407677924077182040771965-0.143000.000030.00304excludedHepG2PCBP1
SEPRKAA1ENSG00000132356.7chr5-4077502940775074407718204077196540775511407756050.159000.000210.04111includedK562EIF4G2
SEPRKAA1ENSG00000132356.7chr5-407695174076960540767567407677924077182040771965-0.089000.001870.07472excludedHepG2SF3B4
SEPRKAA1ENSG00000132356.7chr5-407695174076960540767567407677924077182040771965-0.119000.000150.00820excludedK562UTP18
SEPRKAA1ENSG00000132356.7chr5-4077502940775074407718204077196540775511407756050.197000.000080.00484includedK562HNRNPU
SEPRKAA1ENSG00000132356.7chr5-407695174076960540767567407677924077182040771965-0.179000.000000.00002excludedK562RBM15
SEPRKAA1ENSG00000132356.7chr5-4076951740769605407675674076779240771820407719650.067000.000780.07490includedK562CPSF6
SEPRKAA1ENSG00000132356.7chr5-4077502940775074407718204077196540775511407756050.267000.000080.02793includedHepG2FUS
SEPRKAA1ENSG00000132356.7chr5-4077502940775074407718204077196540775511407756050.120000.002570.08121includedK562PTBP1
A3SSPRKAA1ENSG00000132356.7chr5-4076951740769740407695174076960540771820407719840.060000.005290.03038longerK562AQR
A3SSPRKAA1ENSG00000132356.7chr5-4077551140775625407755114077560540777546407776880.073000.000120.00103longerK562AQR
A3SSPRKAA1ENSG00000132356.7chr5-4077182040771984407718204077196540775511407756050.103000.001930.01247longerK562AQR
MXEPRKAA1ENSG00000132356.7chr5-40771820407719654077551140775625407695174076960540777546407776880.122000.000040.000541includedK562AQR
MXEPRKAA1ENSG00000132356.7chr5-4077182040771965407755114077560540767608407677924077754640777688-0.201000.000000.000002includedK562AQR
MXEPRKAA1ENSG00000132356.7chr5-4077182040771948407755114077560540767608407677924077754640777688-0.203000.000190.005162includedK562SF3B4
MXEPRKAA1ENSG00000132356.7chr5-4077182040771965407755114077560540767608407677924077754640777688-0.207000.000140.004162includedK562SF3B4
MXEPRKAA1ENSG00000132356.7chr5-40771820407719654077551140775605407695174076960540777546407776880.163000.002670.042521includedK562HNRNPUL1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PRKAA1 is not avaliable on ENCORE database.