PPP2R5A

General Information

Gene Name       : PPP2R5A
Gene ID             : ENSG00000066027.11
Essential Gene : No

Functions

Localization

Domains (AlphaFold: PPP2R5A)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PPP2R5AENSG00000066027.1129.8824.2927.09ENCSR000AEF
HepG2PPP2R5AENSG00000066027.116.9917.0812.04ENCSR985KAT
K562PPP2R5AENSG00000066027.1145.4647.9346.70ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PPP2R5A is not avaliable on ENCORE database.



Proteins bound to RNA
  • PPP2R5A RNA is bound by 22 proteins.  







eCLIP assay for PPP2R5A is not avaliable on ENCORE database.





22 proteins are bound to PPP2R5A RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr1212534402212534512+3'-UTR4.829305.78691HepG2FUBP3
chr1212534562212534638+3'-UTR3.209584.67716K562IGF2BP1
chr1212534413212534479+3'-UTR4.274557.77645HepG2DDX55
chr1212534421212534472+3'-UTR3.322817.02736K562PABPC4
chr1212534433212534482+3'-UTR4.7086339.73905K562PUM2
chr1212534837212534897+3'-UTR3.253177.75976K562IGF2BP2
chr1212534652212534696+3'-UTR4.092864.24698K562IGF2BP1
chr1212534823212534982+3'-UTR3.7828513.06787K562IGF2BP1
chr1212534472212534524+3'-UTR4.021277.27995K562PABPC4
chr1212534821212534943+3'-UTR3.164474.38724K562HNRNPK
chr1212534482212534526+3'-UTR4.2665419.54667K562PUM2
chr1212534476212534523+3'-UTR3.886963.32513K562DDX6
chr1212534707212534823+3'-UTR4.6649420.66308K562IGF2BP1
chr1212534192212534276+3'-UTR4.3236428.71368K562PUM2
chr1212534897212534987+3'-UTR3.5649310.41103K562IGF2BP2
chr1212459445212459587+5'-UTR,CDS3.584955.44438HepG2DDX3X
chr1212459015212459075+5'-UTR3.486333.63681K562RBM15
chr1212459275212459363+5'-UTR3.793758.58457HepG2DDX3X
chr1212458997212459093+5'-UTR3.206745.32728HepG2DDX3X
chr1212458904212458917+5'-UTR4.703476.75419HepG2DDX3X
chr1212459215212459275+5'-UTR3.502046.48236HepG2DDX3X
chr1212458893212458951+5'-UTR4.616943.20137K562DDX52
chr1212458882212459005+5'-UTR3.017445.26712K562DDX3X
chr1212459632212459678+CDS,intron-Proximal4.559497.50107K562AQR
chr1212532027212532047+CDS,intron-Proximal4.134624.30417K562YBX3
chr1212531975212532039+CDS,intron-Proximal5.776727.41223K562SF3B4
chr1212530598212530626+CDS3.078763.67697K562YBX3
chr1212530017212530091+CDS,intron-Proximal4.374887.50107K562AQR
chr1212502553212502616+CDS4.746567.79602K562YBX3
chr1212506876212506949+CDS,intron-Proximal3.158963.16985K562SRSF7
chr1212459581212459625+CDS3.997343.15006K562RBM15
chr1212517045212517142+intron-Distal4.041263.75546HepG2KHSRP
chr1212476286212476395+intron-Distal4.879117.39957K562KHSRP
chr1212459839212460010+intron-Distal4.354304.24113K562MATR3
chr1212466579212466664+intron-Distal4.120298.17387K562KHSRP
chr1212507003212507060+intron-Distal,intron-Proximal3.803356.59336K562KHSRP
chr1212476179212476264+intron-Distal4.416466.07567K562KHSRP
chr1212508097212508190+intron-Distal4.565889.63457K562KHSRP
chr1212507645212507704+intron-Distal3.955213.60940HepG2HNRNPC
chr1212517154212517251+intron-Distal4.263024.07352K562KHSRP
chr1212478761212478824+intron-Distal3.058033.35050HepG2SUGP2
chr1212464607212464673+intron-Distal4.207588.42721HepG2QKI
chr1212488702212488790+intron-Distal3.663294.09242HepG2QKI
chr1212522601212522747+intron-Distal,intron-Proximal3.293726.18396K562KHSRP
chr1212464946212465054+intron-Distal3.996599.36317K562QKI
chr1212464957212465061+intron-Distal4.1875212.72659HepG2QKI
chr1212530694212530767+intron-Distal,intron-Proximal4.559685.17894K562PRPF8
chr1212478767212478842+intron-Distal4.247673.62366HepG2HNRNPM
chr1212506948212507003+intron-Proximal3.638554.70224K562KHSRP
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PPP2R5A is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PPP2R5A is not available on ENCORE database.

  • 108 RBPs can affect the levels of PPP2R5A.  








The Knockdown/knockout RNA-Seq assay for PPP2R5A is not available on ENCORE database.





108 RBPs can affect the gene expression of PPP2R5A :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PPP2R5AENSG00000066027.7923.84270558.832100.725108.187906.45870HepG2AATF
PPP2R5AENSG00000066027.7540.65290768.56100-0.507502.952601.97640HepG2ABCF1
PPP2R5AENSG00000066027.7944.24050789.291300.258502.367601.79820HepG2ACO1
PPP2R5AENSG00000066027.7500.38790668.47780-0.417802.687501.70310HepG2ADAR
PPP2R5AENSG00000066027.71336.179901117.427900.257802.232001.60300HepG2AUH
PPP2R5AENSG00000066027.7673.73290933.65700-0.470702.727101.75930HepG2CCAR1
PPP2R5AENSG00000066027.7889.920101155.16130-0.376302.552801.80720HepG2CIRBP
PPP2R5AENSG00000066027.7513.00580789.15260-0.621309.536808.44790HepG2CKAP4
PPP2R5AENSG00000066027.7804.65930632.995600.346102.474401.43060HepG2CPSF7
PPP2R5AENSG00000066027.7820.51370572.125300.520103.036901.59240HepG2CSTF2T
PPP2R5AENSG00000066027.71286.327301035.114900.313403.329502.63730HepG2CELF1
PPP2R5AENSG00000066027.7526.92380729.99650-0.470305.857704.70550HepG2DDX19B
PPP2R5AENSG00000066027.7481.07910616.68740-0.358302.200201.58840HepG2DDX21
PPP2R5AENSG00000066027.71707.208901278.678400.416903.894002.37560HepG2DDX47
PPP2R5AENSG00000066027.7746.60500401.238600.895805.416904.06310HepG2DDX59
PPP2R5AENSG00000066027.71989.401401209.116700.718307.447506.47880HepG2DDX6
PPP2R5AENSG00000066027.7829.02880649.231200.352602.442301.52020HepG2DHX30
PPP2R5AENSG00000066027.7431.04840675.71010-0.648605.038903.82870HepG2EEF2
PPP2R5AENSG00000066027.7889.44550567.790500.647404.749803.29520HepG2AGO1
PPP2R5AENSG00000066027.71916.546601162.462400.721208.553407.54730HepG2EIF2S1
PPP2R5AENSG00000066027.7735.143401284.71040-0.805308.270607.17090HepG2EIF4A3
PPP2R5AENSG00000066027.71817.727301051.856500.789103.827902.88060HepG2EIF4G2
PPP2R5AENSG00000066027.7501.06090665.81200-0.410102.469401.43780HepG2ESF1
PPP2R5AENSG00000066027.7850.905901296.05920-0.607105.753904.77950HepG2FXR1
PPP2R5AENSG00000066027.7867.021101202.36900-0.471703.461602.72100HepG2G3BP1
PPP2R5AENSG00000066027.7987.647001276.35900-0.370002.563801.70900HepG2G3BP2
PPP2R5AENSG00000066027.7316.10170488.39790-0.627704.346003.21360HepG2GEMIN5
PPP2R5AENSG00000066027.7416.08820679.58000-0.707806.491105.56220HepG2HNRNPA1
PPP2R5AENSG00000066027.7452.11520755.90210-0.741507.482806.38850HepG2HNRNPC
PPP2R5AENSG00000066027.71258.789901013.856900.312103.983703.18640HepG2HNRNPL
PPP2R5AENSG00000066027.7281.75340535.49770-0.926409.847308.24520HepG2HNRNPM
PPP2R5AENSG00000066027.7466.02150750.90490-0.6882010.281109.17480HepG2HNRNPU
PPP2R5AENSG00000066027.7876.482601222.21170-0.479703.789603.00990HepG2IGF2BP2
PPP2R5AENSG00000066027.7613.17110767.02540-0.323003.390002.58480HepG2ILF2
PPP2R5AENSG00000066027.7624.492001296.51090-1.0539014.8816013.41740HepG2MAGOH
PPP2R5AENSG00000066027.7787.672501334.52610-0.760708.136407.07730HepG2NCBP2
PPP2R5AENSG00000066027.7262.50370652.83120-1.314404.274101.43210HepG2NPM1
PPP2R5AENSG00000066027.72246.349701429.833100.651603.647702.61750HepG2PABPC1
PPP2R5AENSG00000066027.7786.922801188.57960-0.594905.329004.33730HepG2PABPC4
PPP2R5AENSG00000066027.71001.16030712.397700.490802.642301.62810HepG2PCBP2
PPP2R5AENSG00000066027.7335.48890453.62080-0.435202.791701.55630HepG2PKM
PPP2R5AENSG00000066027.72186.512301402.914500.640104.058702.21000HepG2PNPT1
PPP2R5AENSG00000066027.7930.277201202.49330-0.370304.156903.51680HepG2PTBP1
PPP2R5AENSG00000066027.7608.967801053.52990-0.7908010.786309.71290HepG2PUF60
PPP2R5AENSG00000066027.72680.27520687.583701.9627027.7653025.77160HepG2RAVER1
PPP2R5AENSG00000066027.71466.18800743.896400.9788020.6345018.67190HepG2RBM15
PPP2R5AENSG00000066027.7762.370801072.25080-0.492104.249203.64270HepG2RBM22
PPP2R5AENSG00000066027.71537.752101181.978400.379503.603002.84090HepG2RBM25
PPP2R5AENSG00000066027.7740.497401338.28190-0.8538019.2153018.04040HepG2NELFE
PPP2R5AENSG00000066027.7851.485901246.38730-0.549708.913707.90150HepG2RECQL
PPP2R5AENSG00000066027.7833.06070631.006000.400702.751102.06950HepG2RPLP0
PPP2R5AENSG00000066027.7274.46820533.74200-0.9595010.560709.45470HepG2RPS19
PPP2R5AENSG00000066027.7889.316001570.70960-0.820607.739206.41950HepG2RPS3A
PPP2R5AENSG00000066027.7940.22000450.575701.0611012.8809011.38940HepG2RRP9
PPP2R5AENSG00000066027.7551.26270668.71700-0.278702.149501.56910HepG2SAFB2
PPP2R5AENSG00000066027.7823.961601479.10330-0.844108.772806.55060HepG2SART3
PPP2R5AENSG00000066027.7846.806701251.99890-0.564109.249908.26550HepG2SF3B4
PPP2R5AENSG00000066027.7471.30430779.84200-0.7265012.5514011.33580HepG2SMN1
PPP2R5AENSG00000066027.71678.519201211.105200.470808.538307.79060HepG2SRFBP1
PPP2R5AENSG00000066027.7848.526201306.79610-0.6230011.4229010.60360HepG2SRSF1
PPP2R5AENSG00000066027.7616.06180407.092700.597603.412302.29010HepG2SRSF3
PPP2R5AENSG00000066027.71934.996201063.131300.8639027.5288026.12900HepG2SRSF9
PPP2R5AENSG00000066027.7768.622401051.59140-0.452203.968103.37800HepG2SSB
PPP2R5AENSG00000066027.71502.29080642.535301.2252013.5676011.12620HepG2SUB1
PPP2R5AENSG00000066027.7628.428201183.00260-0.9126022.8879021.38160HepG2SUCLG1
PPP2R5AENSG00000066027.7364.96790524.09620-0.522104.160303.01960HepG2SUPT6H
PPP2R5AENSG00000066027.71490.413501079.304500.465504.176403.15810HepG2TIA1
PPP2R5AENSG00000066027.7309.85230729.66330-1.2357016.7476015.70480HepG2TIAL1
PPP2R5AENSG00000066027.7787.718001029.25540-0.385803.231902.28030HepG2TUFM
PPP2R5AENSG00000066027.7216.05980622.91720-1.527605.808904.33020HepG2U2AF2
PPP2R5AENSG00000066027.7961.26850347.140201.4693026.6007024.37790HepG2UCHL5
PPP2R5AENSG00000066027.71461.65250675.956601.1125011.666109.09690HepG2XRCC5
PPP2R5AENSG00000066027.71302.867301801.37600-0.467408.024007.12800K562AGGF1
PPP2R5AENSG00000066027.71584.077201903.31980-0.264902.908901.36280K562AKAP1
PPP2R5AENSG00000066027.72413.070701874.409800.364303.549902.80650K562AKAP8L
PPP2R5AENSG00000066027.71683.682102990.07490-0.8286014.8778013.66810K562AQR
PPP2R5AENSG00000066027.72497.358001966.700300.344504.629803.41360K562ATP5C1
PPP2R5AENSG00000066027.7539.89460744.87950-0.464303.358702.17300K562CCAR1
PPP2R5AENSG00000066027.72783.441002152.754900.370602.955901.73090K562CCDC124
PPP2R5AENSG00000066027.72004.425902839.75540-0.502606.098904.24190K562CIRBP
PPP2R5AENSG00000066027.71229.819202178.41520-0.8248021.7751018.96140K562CPEB4
PPP2R5AENSG00000066027.73453.230604484.20130-0.376906.049204.61440K562CELF1
PPP2R5AENSG00000066027.71899.743002254.12100-0.246802.891002.22460K562DDX47
PPP2R5AENSG00000066027.7580.91210833.86700-0.521504.165302.47630K562DHX30
PPP2R5AENSG00000066027.72722.169402017.021800.432407.398005.84860K562DKC1
PPP2R5AENSG00000066027.7933.798401365.15460-0.547903.689302.18190K562EEF2
PPP2R5AENSG00000066027.7398.85090757.68120-0.925706.478304.88870K562EIF3A
PPP2R5AENSG00000066027.71949.238701412.460000.464603.661102.45540K562EIF3D
PPP2R5AENSG00000066027.71357.607601676.37280-0.304303.210202.35560K562EIF3G
PPP2R5AENSG00000066027.71157.941902014.80580-0.7991013.4836011.61020K562EIF4A3
PPP2R5AENSG00000066027.71426.539101814.42480-0.347004.097702.64340K562EIF4B
PPP2R5AENSG00000066027.71498.008902095.31020-0.484108.447807.46210K562FXR1
PPP2R5AENSG00000066027.72940.757502221.601700.404502.111601.50550K562G3BP2
PPP2R5AENSG00000066027.71299.793001630.89330-0.327403.539102.25110K562GLRX3
PPP2R5AENSG00000066027.71840.365902347.65540-0.351203.660202.79490K562GRSF1
PPP2R5AENSG00000066027.71227.088602224.03580-0.8579018.0154015.61940K562HNRNPA1
PPP2R5AENSG00000066027.7763.449101380.55430-0.8546014.1052012.84010K562HNRNPC
PPP2R5AENSG00000066027.7906.251501232.86060-0.444004.102202.68040K562HNRNPF
PPP2R5AENSG00000066027.71393.394302037.11320-0.547907.514305.68990K562HNRNPL
PPP2R5AENSG00000066027.71985.939902462.95020-0.310603.743402.70240K562HNRNPU
PPP2R5AENSG00000066027.72120.321702694.39560-0.345702.589601.44910K562IGF2BP3
PPP2R5AENSG00000066027.71750.586902784.60530-0.669609.210607.62080K562MAGOH
PPP2R5AENSG00000066027.71765.584302779.11460-0.654509.443907.63960K562MATR3
PPP2R5AENSG00000066027.72907.842702228.438200.383804.455903.24860K562MBNL1
PPP2R5AENSG00000066027.71194.055801714.69610-0.522108.816007.44830K562MTPAP
PPP2R5AENSG00000066027.72295.962801561.972700.555604.390803.20170K562NAA15
PPP2R5AENSG00000066027.71518.010601905.04420-0.327604.888003.93550K562NSUN2
PPP2R5AENSG00000066027.7822.757801235.91210-0.587005.352504.19150K562PCBP3
PPP2R5AENSG00000066027.7699.92210947.98690-0.437704.018903.04740K562POLR2G
PPP2R5AENSG00000066027.73012.088301858.926100.6962010.294209.29260K562PUS1
PPP2R5AENSG00000066027.72212.830501811.222000.288803.202102.57140K562RBM15
PPP2R5AENSG00000066027.71783.184602594.66760-0.541104.948603.78480K562RBM22
PPP2R5AENSG00000066027.7763.021001129.38070-0.565706.659005.11950K562RCC2
PPP2R5AENSG00000066027.72182.267702730.33960-0.323302.516601.47970K562NELFE
PPP2R5AENSG00000066027.7624.96920844.67880-0.434603.500702.27590K562SAFB
PPP2R5AENSG00000066027.71028.889801869.85300-0.861804.206101.36750K562SART3
PPP2R5AENSG00000066027.71394.117002311.18150-0.7293014.8856012.77890K562SF3B4
PPP2R5AENSG00000066027.7597.66230820.45520-0.457103.587902.13150K562SLBP
PPP2R5AENSG00000066027.71179.264101834.39630-0.637404.512902.24180K562SMN1
PPP2R5AENSG00000066027.71512.586101926.11530-0.348702.857201.90940K562SRPK2
PPP2R5AENSG00000066027.72125.430502652.01890-0.319303.304002.53560K562SRSF1
PPP2R5AENSG00000066027.7811.788001084.14270-0.417403.649902.41650K562SRSF4
PPP2R5AENSG00000066027.72445.857603471.05980-0.505009.326406.83410K562SUCLG1
PPP2R5AENSG00000066027.7770.425901242.97690-0.690106.644705.01920K562SUPV3L1
PPP2R5AENSG00000066027.71778.659602684.26810-0.593705.698304.66220K562TARDBP
PPP2R5AENSG00000066027.71896.688702589.21350-0.449004.906503.77080K562TIA1
PPP2R5AENSG00000066027.7817.629501190.57020-0.542104.616803.38500K562TIAL1
PPP2R5AENSG00000066027.72061.848802540.19200-0.301002.584001.53380K562TRA2A
PPP2R5AENSG00000066027.7978.612601264.86250-0.370202.886701.91810K562TRIM56
PPP2R5AENSG00000066027.71459.294202154.69830-0.562204.226902.81670K562U2AF1
PPP2R5AENSG00000066027.71394.546002224.92730-0.6740012.1166010.41870K562U2AF2
PPP2R5AENSG00000066027.71299.429501797.46390-0.468104.870203.77600K562WDR43
PPP2R5AENSG00000066027.72536.296203368.39530-0.409304.627003.46810K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PPP2R5A is not available on ENCORE database.





7 RBPs can affect the splicing of PPP2R5A :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPPP2R5AENSG00000066027.7chr1+212522530212522584212521730212521839212529967212530018-0.177000.011210.09984excludedHepG2U2AF2
SEPPP2R5AENSG00000066027.7chr1+212522530212522584212521730212521839212529967212530018-0.058000.000010.00029excludedK562AQR
SEPPP2R5AENSG00000066027.7chr1+212515529212515622212506873212506940212519144212519275-0.056000.002660.02781excludedK562AQR
SEPPP2R5AENSG00000066027.7chr1+212520688212520748212519144212519275212529967212530018-0.075000.002450.03547excludedK562PUS1
SEPPP2R5AENSG00000066027.7chr1+212502476212502673212458878212459633212506838212506940-0.066000.001620.02948excludedK562U2AF2
SEPPP2R5AENSG00000066027.7chr1+212515529212515622212506838212506940212519144212519275-0.077000.000050.00367excludedK562HNRNPU
A3SSPPP2R5AENSG00000066027.7chr1+2125191312125192752125191442125192752125155292125156220.103000.000000.00003longerK562U2AF2
A3SSPPP2R5AENSG00000066027.7chr1+2125191312125192752125191442125192752125155292125156220.062000.000340.01873longerK562U2AF1
MXEPPP2R5AENSG00000066027.7chr1+212502476212502673212506838212506940212458878212459633212515529212515622-0.164000.000110.006172includedHepG2TAF15
MXEPPP2R5AENSG00000066027.7chr1+2125024762125026732125068382125069402124588782124596332125155292125156220.102000.001320.075361includedK562TRA2A

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PPP2R5A is not avaliable on ENCORE database.