PON2

General Information

Gene Name       : PON2
Gene ID             : ENSG00000105854.12
Essential Gene : No

Functions

Localization

Domains (AlphaFold: PON2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PON2ENSG00000105854.1240.1738.6439.41ENCSR000AEF
HepG2PON2ENSG00000105854.12128.10253.57190.83ENCSR985KAT
K562PON2ENSG00000105854.1214.0315.9715.00ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PON2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • PON2 RNA is bound by 15 proteins.  







eCLIP assay for PON2 is not avaliable on ENCORE database.





15 proteins are bound to PON2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr79504102595041078-3'-UTR,CDS,intron-Distal,intron-Proximal3.115238.80715HepG2BCLAF1
chr79503475895034801-3'-UTR,CDS,intron-Distal3.334953.85049HepG2SND1
chr79503466195034762-3'-UTR,CDS,intron-Distal3.226145.88140HepG2LSM11
chr79503447895034524-3'-UTR,intron-Distal,intron-Proximal3.275658.46777HepG2LARP4
chr79504096795041012-3'-UTR,CDS,intron-Distal,intron-Proximal3.264026.09950HepG2BCLAF1
chr79504102695041074-3'-UTR,CDS,intron-Distal,intron-Proximal3.412178.56612HepG2LIN28B
chr79504174295041811-3'-UTR,CDS,intron-Distal,intron-Proximal3.0277215.09474HepG2U2AF2
chr79503546095035524-3'-UTR,CDS,intron-Distal3.089985.93547HepG2SND1
chr79503475895034800-3'-UTR,CDS,intron-Distal3.740859.63482HepG2GRWD1
chr79503473695034758-3'-UTR,CDS,intron-Distal4.296434.69071HepG2GRWD1
chr79504174595041785-3'-UTR,CDS,intron-Distal,intron-Proximal3.384436.17692HepG2RPS3
chr79503427195034317-3'-UTR,intron-Distal4.8661816.91714HepG2LIN28B
chr79503920395039244-3'-UTR,CDS,intron-Distal,intron-Proximal3.506563.94979HepG2BCLAF1
chr79506425895064328-5'-UTR,CDS,intron-Distal,intron-Proximal5.26519400.00000HepG2DDX3X
chr79506419695064338-5'-UTR,CDS,intron-Distal,intron-Proximal3.7072120.34988HepG2RPS3
chr79506419195064258-CDS,intron-Distal4.94146400.00000HepG2DDX3X
chr79503716695037279-intron-Distal3.573033.97268K562PTBP1
chr79503718995037266-intron-Distal5.467967.11021HepG2PTBP1
chr79504498795045100-intron-Distal,intron-Proximal3.822896.39201HepG2HNRNPC
chr79503765695037731-intron-Distal4.340559.23696HepG2PCBP2
chr79505010495050192-intron-Distal3.745665.36861HepG2U2AF2
chr79503750695037601-intron-Distal3.248374.54387HepG2PTBP1
chr79506405895064160-intron-Distal6.1785617.15870HepG2EFTUD2
chr79504490895044964-intron-Distal3.370803.94088HepG2QKI
chr79506399695064058-intron-Distal6.0695911.05222HepG2EFTUD2
chr79504521395045269-intron-Distal3.421177.32838HepG2HNRNPC
chr79504482195044903-intron-Distal5.610947.62903HepG2QKI
chr79505092895051027-intron-Distal3.822323.59803HepG2PTBP1
chr79504539495045462-intron-Distal,intron-Proximal3.084824.78803HepG2TIAL1
chr79503714595037189-intron-Distal3.425553.59803HepG2PTBP1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PON2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PON2 is not available on ENCORE database.

  • 121 RBPs can affect the levels of PON2.  








The Knockdown/knockout RNA-Seq assay for PON2 is not available on ENCORE database.





121 RBPs can affect the gene expression of PON2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PON2ENSG00000105854.87775.629803058.178901.34620112.38630110.00840HepG2ACO1
PON2ENSG00000105854.810156.932204305.403701.2381024.6152023.20620HepG2AKAP1
PON2ENSG00000105854.85516.340202604.805701.0824015.4533013.22050HepG2AKAP8
PON2ENSG00000105854.83912.945003072.574900.348706.532105.40320HepG2AKAP8L
PON2ENSG00000105854.84945.516703562.420100.473204.893803.86180HepG2ASCC1
PON2ENSG00000105854.88606.890204973.008900.7913035.3597033.39870HepG2AUH
PON2ENSG00000105854.82395.753903918.38880-0.709804.967703.70870HepG2BCCIP
PON2ENSG00000105854.82331.016604611.23820-0.984208.533807.55170HepG2BOP1
PON2ENSG00000105854.83762.874302905.797200.372804.326702.80480HepG2BUD13
PON2ENSG00000105854.87815.101404916.739100.6685016.1633014.57240HepG2CALR
PON2ENSG00000105854.86124.250903384.525000.8555015.3978013.74460HepG2CIRBP
PON2ENSG00000105854.83869.828702510.028600.624502.539301.80810HepG2CNOT7
PON2ENSG00000105854.86077.940404233.512800.521605.341504.41540HepG2CPSF6
PON2ENSG00000105854.84741.025203194.012200.569709.930707.98720HepG2CPSF7
PON2ENSG00000105854.812208.967905504.771001.1491051.7824049.72940HepG2CELF1
PON2ENSG00000105854.84006.152805919.37590-0.5632024.4962022.70180HepG2DAZAP1
PON2ENSG00000105854.82377.184502828.39270-0.250704.012603.03110HepG2DDX19B
PON2ENSG00000105854.84752.478203936.758800.271603.623102.29940HepG2DDX1
PON2ENSG00000105854.84456.650403160.380300.495806.647205.64570HepG2DDX21
PON2ENSG00000105854.88007.929003852.371401.0556020.0128018.20910HepG2DDX55
PON2ENSG00000105854.82465.069203552.81170-0.527306.439504.95430HepG2DDX5
PON2ENSG00000105854.85591.404103542.624100.658307.501306.52960HepG2DDX6
PON2ENSG00000105854.83398.591802925.857100.216002.802102.12090HepG2DKC1
PON2ENSG00000105854.85327.181303860.265500.464609.993008.72120HepG2DNAJC21
PON2ENSG00000105854.82908.439803825.94430-0.3956010.919709.72150HepG2DNAJC2
PON2ENSG00000105854.84029.586303303.192100.286702.250801.41760HepG2EEF2
PON2ENSG00000105854.83768.417902909.160400.373302.374001.35300HepG2AGO1
PON2ENSG00000105854.84410.596303405.911800.372803.158202.52650HepG2EIF2S1
PON2ENSG00000105854.84078.904502942.088000.471207.341005.54760HepG2EIF2S2
PON2ENSG00000105854.84068.649502681.484600.601407.676706.23980HepG2EIF3D
PON2ENSG00000105854.85269.117003664.580600.523803.968803.15160HepG2EIF4B
PON2ENSG00000105854.87820.476705709.632100.4538012.9295011.78780HepG2ETF1
PON2ENSG00000105854.83374.729502396.524400.493708.181106.14960HepG2FAM120A
PON2ENSG00000105854.88793.899603915.937201.1670023.9236022.07570HepG2FIP1L1
PON2ENSG00000105854.81229.839303206.79040-1.3827014.1741011.74380HepG2FKBP4
PON2ENSG00000105854.82724.312404240.46780-0.638302.623401.63550HepG2FTO
PON2ENSG00000105854.85580.912903879.698100.524503.746902.45240HepG2FUS
PON2ENSG00000105854.85150.612703522.837000.547904.592203.74400HepG2G3BP1
PON2ENSG00000105854.85373.114103397.320100.661303.726002.53880HepG2GNB2L1
PON2ENSG00000105854.83608.683504799.41360-0.411402.295101.70910HepG2GPKOW
PON2ENSG00000105854.85203.748503655.127800.509503.238001.52730HepG2GTF2F1
PON2ENSG00000105854.84512.820402919.705700.6281020.2368018.03750HepG2HDGF
PON2ENSG00000105854.83007.935903897.24530-0.373703.820903.08010HepG2HNRNPA1
PON2ENSG00000105854.87900.864405439.885200.5383016.2734014.39090HepG2HNRNPA2B1
PON2ENSG00000105854.83206.582605110.12210-0.6723022.6965020.91950HepG2HNRNPF
PON2ENSG00000105854.85469.793203566.650200.616809.371308.14670HepG2HNRNPK
PON2ENSG00000105854.85676.290104580.132800.309502.114301.55640HepG2HNRNPLL
PON2ENSG00000105854.83376.434002702.045400.321303.611502.53590HepG2HNRNPM
PON2ENSG00000105854.83360.231604306.23340-0.357907.412006.45710HepG2HNRNPU
PON2ENSG00000105854.84132.514502837.065300.542504.321002.77480HepG2HSPD1
PON2ENSG00000105854.82900.785905032.03570-0.7947020.1657018.40700HepG2IGF2BP1
PON2ENSG00000105854.86905.085303360.252901.039005.187103.86080HepG2IGF2BP3
PON2ENSG00000105854.84789.884003601.689000.411202.831101.81670HepG2KHSRP
PON2ENSG00000105854.83177.322102795.579800.184602.692601.68500HepG2KIF1C
PON2ENSG00000105854.84875.588503328.279600.550708.184406.32970HepG2LARP7
PON2ENSG00000105854.82019.091003494.79160-0.7915014.1863011.65370HepG2LIN28B
PON2ENSG00000105854.82964.507003798.68040-0.357702.827402.16570HepG2MAGOH
PON2ENSG00000105854.83826.489902818.451200.441004.479702.46960HepG2MARK2
PON2ENSG00000105854.85476.127202806.435900.9643010.512708.58900HepG2METAP2
PON2ENSG00000105854.87370.181003169.647801.2173042.8950040.38640HepG2MSI2
PON2ENSG00000105854.83576.129402661.482800.426105.406503.71910HepG2NAA15
PON2ENSG00000105854.87273.303605869.619800.309203.425602.57800HepG2NOL12
PON2ENSG00000105854.81305.754104060.87550-1.6369016.4132014.76700HepG2NSUN2
PON2ENSG00000105854.85076.479003482.425800.543605.955704.90710HepG2PABPC4
PON2ENSG00000105854.85691.050004262.530900.416909.915508.47740HepG2PARN
PON2ENSG00000105854.84342.255303575.130800.280304.827604.06130HepG2PCBP1
PON2ENSG00000105854.81260.433702250.52070-0.836304.781602.82040HepG2PNPT1
PON2ENSG00000105854.82334.716903840.82960-0.7182020.0476018.20210HepG2PPIL4
PON2ENSG00000105854.81291.654103165.18800-1.2931064.3798061.72000HepG2PRPF4
PON2ENSG00000105854.85521.176903637.913400.6018018.2057017.03530HepG2PTBP1
PON2ENSG00000105854.82634.874905602.95590-1.0885032.3144030.55890HepG2PUF60
PON2ENSG00000105854.86518.865005947.656200.132201.810401.30800HepG2PUM1
PON2ENSG00000105854.88138.209405943.391900.453306.610405.59020HepG2PUM2
PON2ENSG00000105854.84840.965403114.958400.6360024.5151023.02020HepG2PUS1
PON2ENSG00000105854.82752.165503939.77070-0.5175010.031208.94600HepG2QKI
PON2ENSG00000105854.86675.126903545.014500.912907.662306.52240HepG2RAVER1
PON2ENSG00000105854.84914.797603955.307600.313203.976102.96970HepG2RBM15
PON2ENSG00000105854.87687.754204772.205800.6878022.3231021.13600HepG2RBM22
PON2ENSG00000105854.85796.995403575.662900.6970013.9688012.51980HepG2RBM25
PON2ENSG00000105854.85011.221804048.578400.307605.764105.02820HepG2NELFE
PON2ENSG00000105854.83038.270003770.82740-0.311605.384404.56000HepG2RECQL
PON2ENSG00000105854.84022.317205504.49100-0.452605.728604.79700HepG2RPLP0
PON2ENSG00000105854.84789.128903778.295300.341903.117501.97110HepG2RPS5
PON2ENSG00000105854.85905.965402941.008101.0058018.3332016.64590HepG2RRP9
PON2ENSG00000105854.81956.176903834.93700-0.9712051.0539048.83440HepG2SAFB2
PON2ENSG00000105854.83574.858102618.751500.448904.795503.57180HepG2SERBP1
PON2ENSG00000105854.83337.785005372.09670-0.6866033.9513032.05370HepG2SLBP
PON2ENSG00000105854.86040.120404472.261700.4335016.5410015.17000HepG2SMN1
PON2ENSG00000105854.811048.471005044.405001.131004.725703.69220HepG2SNRNP70
PON2ENSG00000105854.89771.409105390.048300.8582052.8374051.36910HepG2SRFBP1
PON2ENSG00000105854.84953.852103953.273200.325407.056606.38430HepG2SRSF1
PON2ENSG00000105854.87677.125205531.948400.472705.602304.75730HepG2SRSF5
PON2ENSG00000105854.83559.964305020.44240-0.4960013.0472011.72850HepG2SRSF7
PON2ENSG00000105854.85280.048303216.251300.715106.852306.05300HepG2SRSF9
PON2ENSG00000105854.83600.333702825.725800.349402.544601.31340HepG2SSRP1
PON2ENSG00000105854.84942.330403312.742300.577104.333202.81710HepG2SUB1
PON2ENSG00000105854.83182.080302644.523700.266902.779501.83690HepG2SUPT6H
PON2ENSG00000105854.84522.325603553.527000.347705.891505.12540HepG2TAF15
PON2ENSG00000105854.84970.415602570.890300.9510017.0791015.06700HepG2TFIP11
PON2ENSG00000105854.81708.764603265.02580-0.9341023.8856021.48480HepG2TIA1
PON2ENSG00000105854.82255.336904184.60140-0.8917026.0713024.82920HepG2TIAL1
PON2ENSG00000105854.85243.570604221.696200.312606.095905.31660HepG2TRIM56
PON2ENSG00000105854.84303.340003350.025900.361203.346702.66180HepG2U2AF1
PON2ENSG00000105854.87689.650302974.715701.370105.755104.28250HepG2U2AF2
PON2ENSG00000105854.85930.426803036.107100.9658037.5204035.56790HepG2UPF1
PON2ENSG00000105854.84298.666202931.254600.5523017.2447015.94040HepG2UTP3
PON2ENSG00000105854.85263.044903898.012500.433102.683801.64460HepG2XRCC6
PON2ENSG00000105854.82865.005603775.44180-0.398102.039301.40920HepG2XRN2
PON2ENSG00000105854.83493.493903123.677500.161302.101801.50430HepG2ZC3H8
PON2ENSG00000105854.8486.45040388.172300.325502.097901.59150K562AGGF1
PON2ENSG00000105854.8645.23860403.914200.675706.466305.43600K562AKAP8L
PON2ENSG00000105854.8567.79890423.809400.421903.432002.40460K562ATP5C1
PON2ENSG00000105854.8254.45770364.68730-0.519203.415201.92330K562BCCIP
PON2ENSG00000105854.8705.01960463.876400.603806.395604.57560K562CCDC124
PON2ENSG00000105854.81203.74840815.329500.562007.194305.64500K562CELF1
PON2ENSG00000105854.8642.37190455.432600.496103.787702.06430K562DDX19B
PON2ENSG00000105854.8437.97100550.97360-0.331102.270701.67170K562DDX47
PON2ENSG00000105854.8292.78950421.56520-0.525903.069402.16390K562FMR1
PON2ENSG00000105854.8553.62860381.065800.538802.980102.24270K562G3BP2
PON2ENSG00000105854.8546.26810346.258700.657706.740805.00820K562GLRX3
PON2ENSG00000105854.8409.11110539.60980-0.399402.309601.61540K562GRSF1
PON2ENSG00000105854.8508.98130306.935400.729602.668701.47720K562HNRNPA2B1
PON2ENSG00000105854.8682.63740428.642300.671206.262404.90600K562KIF1C
PON2ENSG00000105854.8521.30420337.772800.626003.555902.48250K562KRR1
PON2ENSG00000105854.8290.69710422.68120-0.540102.555201.74700K562MAGOH
PON2ENSG00000105854.8657.67370480.189300.453703.329702.31450K562MBNL1
PON2ENSG00000105854.8582.78000336.578900.791905.500804.10520K562NAA15
PON2ENSG00000105854.8953.60150725.360300.394603.016201.45130K562NOL12
PON2ENSG00000105854.8925.79390754.093100.295802.554801.63080K562PUM2
PON2ENSG00000105854.8845.64340400.548401.0780014.5233013.31760K562PUS1
PON2ENSG00000105854.8565.52170390.293700.534904.727203.97160K562RBM15
PON2ENSG00000105854.8481.69190281.883600.772902.677901.47750K562SNRNP200
PON2ENSG00000105854.8598.74170408.933600.550005.925904.62470K562SRPK2
PON2ENSG00000105854.8264.38150393.02070-0.572002.879702.04270K562TIA1
PON2ENSG00000105854.8511.72520381.556600.423402.990502.15590K562U2AF2
PON2ENSG00000105854.8962.02220706.522300.445203.829402.78390K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PON2 is not available on ENCORE database.





7 RBPs can affect the splicing of PON2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
A3SSPON2ENSG00000105854.8chr7-950416239504178995041623950417639504555395045609-0.057000.000000.00111shorterHepG2PTBP1
A3SSPON2ENSG00000105854.8chr7-9503543095035584950354309503555995036298950363800.292000.000960.03605longerK562U2AF2
A3SSPON2ENSG00000105854.8chr7-950409649504109195040964950410559504162395041789-0.063000.000260.02930shorterHepG2SRSF1
A3SSPON2ENSG00000105854.8chr7-950409649504109195040964950410559504162395041789-0.100000.000000.00000shorterHepG2U2AF2
A3SSPON2ENSG00000105854.8chr7-950409649504109195040964950410559504162395041789-0.077000.000010.00092shorterHepG2U2AF1
A3SSPON2ENSG00000105854.8chr7-950409649504109195040964950410559504162395041789-0.058000.000850.09360shorterHepG2PCBP1
A5SSPON2ENSG00000105854.8chr7-9503921295039413950392659503941395036298950363800.099000.000150.06614longerHepG2XRN2
MXEPON2ENSG00000105854.8chr7-95035430950354929503549695035559950342089503480095036298950363800.134000.000580.015021includedHepG2FTO

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PON2 is not avaliable on ENCORE database.