UBE2N

General Information

Gene Name       : UBE2N
Gene ID             : ENSG00000177889.9
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: UBE2N)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878UBE2NENSG00000177889.9303.82268.36286.09ENCSR000AEF
HepG2UBE2NENSG00000177889.9128.42174.98151.70ENCSR985KAT
K562UBE2NENSG00000177889.9181.99203.60192.80ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for UBE2N is not avaliable on ENCORE database.



Proteins bound to RNA
  • UBE2N RNA is bound by 21 proteins.  







eCLIP assay for UBE2N is not avaliable on ENCORE database.





21 proteins are bound to UBE2N RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr129381808893818182-3'-UTR,intron-Distal,intron-Proximal4.230954.37030K562KHSRP
chr129380450993804604-3'-UTR,CDS,intron-Distal,intron-Proximal3.643873.24162HepG2G3BP1
chr129380253193802564-3'-UTR,intron-Distal3.757614.30677K562YBX3
chr129380232393802378-3'-UTR,intron-Distal4.087613.54095K562FAM120A
chr129381808193818169-3'-UTR,intron-Distal,intron-Proximal3.121703.46866HepG2U2AF2
chr129380499893805077-3'-UTR,CDS,intron-Distal,intron-Proximal3.2117113.61786K562DDX3X
chr129380206293802137-3'-UTR,intron-Distal,intron-Proximal4.698387.41617HepG2CSTF2
chr129380333693803378-3'-UTR,intron-Distal3.786143.21228K562TIA1
chr129380322893803329-3'-UTR,intron-Distal3.194499.60340K562YBX3
chr129380342993803446-3'-UTR,intron-Distal,intron-Proximal3.367244.46957K562TIA1
chr129380327693803388-3'-UTR,intron-Distal3.135669.61608K562UPF1
chr129380335193803452-3'-UTR,intron-Distal,intron-Proximal4.482584.74172HepG2TIAL1
chr129380373993803814-3'-UTR,intron-Distal5.051078.49217K562YBX3
chr129380252193802531-3'-UTR,intron-Distal3.125313.08662K562YBX3
chr129380305093803139-3'-UTR,intron-Distal5.191337.77020HepG2FUBP3
chr129380337893803429-3'-UTR,intron-Distal,intron-Proximal4.423789.86765K562TIA1
chr129380333793803453-3'-UTR,intron-Distal,intron-Proximal3.608444.81659HepG2UPF1
chr129380281593802877-3'-UTR,intron-Distal3.621374.14074K562UPF1
chr129383501093835240-5'-UTR,intron-Distal,intron-Proximal3.260778.07325K562HNRNPM
chr129383558793835666-5'-UTR,CDS,intron-Distal4.8466512.81328HepG2PRPF8
chr129383564293835716-5'-UTR,CDS,intron-Distal,intron-Proximal3.827593.45225K562GRWD1
chr129383486893835009-5'-UTR,intron-Distal4.159818.62305K562NONO
chr129383562993835672-5'-UTR,CDS,intron-Distal4.3229017.55270K562DDX3X
chr129383562493835714-5'-UTR,CDS,intron-Distal,intron-Proximal3.463303.73423K562UCHL5
chr129383516793835348-intron-Distal3.1292215.03378HepG2NKRF
chr129383246593832546-intron-Distal4.489439.35404HepG2QKI
chr129383539893835478-intron-Distal3.481884.01575K562NONO
chr129381077293810832-intron-Distal4.7221319.14538HepG2QKI
chr129383422993834287-intron-Distal4.132613.86368HepG2HNRNPM
chr129381078193810883-intron-Distal3.204115.61499K562QKI
chr129383204193832120-intron-Distal5.6241810.24238HepG2PCBP2
chr129381818293818284-intron-Distal,intron-Proximal3.515995.56048K562KHSRP
chr129381083293810864-intron-Distal5.6746210.31535HepG2QKI
chr129383535093835412-intron-Distal3.075176.23851HepG2NKRF
chr129383506493835159-intron-Distal,intron-Proximal4.893108.09947K562NONO
chr129383540793835497-intron-Distal4.341585.23978HepG2PRPF4
chr129383254693832613-intron-Distal3.367595.10768HepG2QKI
chr129383538793835477-intron-Distal4.388906.63111HepG2XRN2
chr129383527193835346-intron-Distal4.307924.58989K562NONO
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for UBE2N is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for UBE2N is not available on ENCORE database.

  • 123 RBPs can affect the levels of UBE2N.  








The Knockdown/knockout RNA-Seq assay for UBE2N is not available on ENCORE database.





123 RBPs can affect the gene expression of UBE2N :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
UBE2NENSG00000177889.51884.910302465.12880-0.387202.916001.94850HepG2ABCF1
UBE2NENSG00000177889.52251.958901968.797900.193802.268401.70760HepG2ACO1
UBE2NENSG00000177889.5515.156501924.48100-1.9014053.3883050.20600HepG2ADAR
UBE2NENSG00000177889.51305.836301888.59870-0.532304.515603.19550HepG2AKAP8
UBE2NENSG00000177889.51412.384701978.18660-0.486009.216907.91960HepG2AKAP8L
UBE2NENSG00000177889.51080.241602679.74890-1.3107027.6696025.57930HepG2ASCC1
UBE2NENSG00000177889.52421.425602845.65210-0.232902.415001.76480HepG2AUH
UBE2NENSG00000177889.51231.994101665.37960-0.434902.721101.82910HepG2BCLAF1
UBE2NENSG00000177889.52189.570102905.91940-0.408302.662001.70940HepG2CCAR1
UBE2NENSG00000177889.51542.553601968.53690-0.351806.367605.43370HepG2CKAP4
UBE2NENSG00000177889.5996.250601767.57830-0.8272012.3014010.96770HepG2CPSF6
UBE2NENSG00000177889.51126.422801707.30410-0.600004.388703.55380HepG2DDX21
UBE2NENSG00000177889.51223.083501669.66510-0.449003.750602.67560HepG2DDX24
UBE2NENSG00000177889.52167.983002664.85320-0.297701.821701.31010HepG2DDX6
UBE2NENSG00000177889.51378.911001883.64930-0.450007.729906.70620HepG2DKC1
UBE2NENSG00000177889.51507.544901937.83070-0.362204.826203.92010HepG2DNAJC21
UBE2NENSG00000177889.51422.168101920.78410-0.433609.424808.30720HepG2DNAJC2
UBE2NENSG00000177889.51358.350201811.98370-0.415703.413202.39670HepG2EEF2
UBE2NENSG00000177889.51792.212302562.02020-0.515505.102404.31160HepG2EIF2S1
UBE2NENSG00000177889.51469.180801870.06710-0.348103.501002.18660HepG2EIF2S2
UBE2NENSG00000177889.51064.211602831.44580-1.4118027.2876025.31670HepG2EIF4A3
UBE2NENSG00000177889.51885.444202756.59550-0.548003.992703.17360HepG2EIF4B
UBE2NENSG00000177889.52474.827302901.29370-0.229402.064101.32290HepG2EIF4G1
UBE2NENSG00000177889.52213.898702779.25950-0.328102.037501.33070HepG2EIF4G2
UBE2NENSG00000177889.52158.185503267.05190-0.5982015.7559014.51370HepG2ETF1
UBE2NENSG00000177889.5891.393101770.61170-0.990105.126603.75300HepG2FTO
UBE2NENSG00000177889.5995.353801655.96720-0.7344011.203509.66660HepG2FUBP3
UBE2NENSG00000177889.51158.135602649.97380-1.1942021.3598019.59170HepG2G3BP1
UBE2NENSG00000177889.52085.896702813.05330-0.431503.955402.88020HepG2G3BP2
UBE2NENSG00000177889.51536.523402003.68290-0.383002.748802.10900HepG2GPKOW
UBE2NENSG00000177889.51425.906101956.39640-0.456305.198304.35050HepG2HNRNPA1
UBE2NENSG00000177889.51490.670102176.15090-0.545806.844105.79160HepG2HNRNPC
UBE2NENSG00000177889.51749.152002214.01600-0.340004.845903.93000HepG2HNRNPF
UBE2NENSG00000177889.51733.655402682.92120-0.630008.480807.31070HepG2HNRNPK
UBE2NENSG00000177889.52200.805802678.89810-0.283605.264204.35970HepG2HNRNPL
UBE2NENSG00000177889.51577.313101912.15190-0.277701.832201.30980HepG2HNRNPLL
UBE2NENSG00000177889.51889.849602161.76190-0.193902.063001.53020HepG2HNRNPU
UBE2NENSG00000177889.51085.823402056.82860-0.9216010.726508.40020HepG2HSPD1
UBE2NENSG00000177889.51702.297902180.18350-0.357003.876903.03110HepG2IGF2BP1
UBE2NENSG00000177889.51895.097002693.70410-0.507305.055204.16680HepG2IGF2BP2
UBE2NENSG00000177889.51799.915802208.16450-0.294905.232104.25040HepG2ILF2
UBE2NENSG00000177889.5857.351101525.72650-0.831507.298205.08020HepG2ILF3
UBE2NENSG00000177889.52084.972202709.28710-0.377902.277501.38040HepG2KHSRP
UBE2NENSG00000177889.51416.736501799.83190-0.345304.687803.36720HepG2KIF1C
UBE2NENSG00000177889.52271.145703067.18320-0.433503.046202.17140HepG2LARP4
UBE2NENSG00000177889.51455.751002857.46600-0.9730015.9082014.39710HepG2MAGOH
UBE2NENSG00000177889.51388.758102014.66420-0.536707.139605.89830HepG2MSI2
UBE2NENSG00000177889.52122.968802941.24650-0.470304.178703.40630HepG2NCBP2
UBE2NENSG00000177889.51313.696501695.49190-0.368102.944402.17330HepG2NSUN2
UBE2NENSG00000177889.51815.492102619.57830-0.529005.191804.21540HepG2PABPC4
UBE2NENSG00000177889.51807.346102139.74710-0.243602.860902.00020HepG2PARN
UBE2NENSG00000177889.51849.394902604.59780-0.4940010.779209.70780HepG2PCBP1
UBE2NENSG00000177889.51464.581001928.11510-0.396705.546004.53370HepG2PPIL4
UBE2NENSG00000177889.51057.644101453.95910-0.459102.933102.10240HepG2PRPF8
UBE2NENSG00000177889.51879.795702650.31260-0.495609.898208.98900HepG2PTBP1
UBE2NENSG00000177889.52318.740602783.69640-0.263702.280601.73160HepG2PUF60
UBE2NENSG00000177889.52326.562602955.00420-0.345007.909807.01380HepG2PUM1
UBE2NENSG00000177889.52342.773602952.85350-0.333904.035203.23050HepG2PUM2
UBE2NENSG00000177889.51656.397002005.37280-0.275803.904403.19730HepG2PUS1
UBE2NENSG00000177889.52286.631702870.27530-0.328004.121503.38000HepG2QKI
UBE2NENSG00000177889.52155.978302690.71400-0.319603.636202.66760HepG2RBM15
UBE2NENSG00000177889.53257.732902730.679500.254503.064502.52720HepG2RBM22
UBE2NENSG00000177889.52080.745602604.98900-0.324203.262402.53610HepG2RBM25
UBE2NENSG00000177889.51502.979902090.48380-0.476004.273903.02450HepG2RBM27
UBE2NENSG00000177889.52168.820302949.51280-0.443608.999808.12580HepG2NELFE
UBE2NENSG00000177889.51831.646202747.12590-0.5848014.8537013.60160HepG2RECQL
UBE2NENSG00000177889.51638.162102384.89070-0.541806.691105.69390HepG2RPLP0
UBE2NENSG00000177889.51064.652401431.28230-0.426904.320603.56910HepG2RPS19
UBE2NENSG00000177889.51060.573701571.37420-0.567204.070903.09910HepG2RPS3A
UBE2NENSG00000177889.51364.263501968.04500-0.528605.103103.62990HepG2RPS5
UBE2NENSG00000177889.51071.392101438.31670-0.424902.472901.72580HepG2RRP9
UBE2NENSG00000177889.51156.645601925.13180-0.7350021.7952020.23350HepG2SAFB2
UBE2NENSG00000177889.51571.963901892.64990-0.267801.896601.30460HepG2SF3B1
UBE2NENSG00000177889.51956.719402759.25130-0.4958010.939209.88310HepG2SF3B4
UBE2NENSG00000177889.51642.041502669.10540-0.7009025.0845023.38390HepG2SLBP
UBE2NENSG00000177889.51683.097002245.00750-0.415609.748708.65830HepG2SMN1
UBE2NENSG00000177889.51632.006902240.08810-0.456902.969301.97440HepG2SMNDC1
UBE2NENSG00000177889.53662.516403084.252700.247804.459003.86680HepG2SRFBP1
UBE2NENSG00000177889.53367.698702880.088000.225603.138002.64270HepG2SRSF1
UBE2NENSG00000177889.52263.778602748.47980-0.279904.043703.31300HepG2SRSF5
UBE2NENSG00000177889.51757.642102175.16360-0.307504.111903.28980HepG2SRSF7
UBE2NENSG00000177889.52020.322902343.12820-0.213902.603302.06370HepG2SRSF9
UBE2NENSG00000177889.51917.450602677.95000-0.481909.631008.78760HepG2SSB
UBE2NENSG00000177889.52257.213303125.79150-0.4697012.6697011.50340HepG2SUCLG1
UBE2NENSG00000177889.51309.101601875.76240-0.518903.685202.92030HepG2SUPV3L1
UBE2NENSG00000177889.51311.544102588.81030-0.9810030.9711029.36260HepG2TAF15
UBE2NENSG00000177889.51319.722501863.76900-0.498005.240304.28690HepG2TARDBP
UBE2NENSG00000177889.51879.212102378.68450-0.340003.629902.67810HepG2TIA1
UBE2NENSG00000177889.51065.331902100.47450-0.9794024.8491023.63440HepG2TIAL1
UBE2NENSG00000177889.51331.423802119.33830-0.6706017.4460016.18970HepG2TRIM56
UBE2NENSG00000177889.52044.947202719.53320-0.411305.060003.84170HepG2TUFM
UBE2NENSG00000177889.5827.309501108.17190-0.421702.751801.99420HepG2UCHL5
UBE2NENSG00000177889.52539.912902135.183400.250303.367002.71860HepG2UTP3
UBE2NENSG00000177889.51403.035201846.47790-0.396202.506701.81380HepG2XRN2
UBE2NENSG00000177889.51356.330802195.90910-0.695106.161104.12460HepG2ZRANB2
UBE2NENSG00000177889.53593.148004547.84240-0.339903.184301.85490K562ABCF1
UBE2NENSG00000177889.5448.308601457.64360-1.7011013.6578010.25620K562ADAR
UBE2NENSG00000177889.52756.717501845.726300.5787014.5887013.39160K562AGGF1
UBE2NENSG00000177889.52396.723401920.549800.319402.798502.14130K562AKAP8L
UBE2NENSG00000177889.53138.997004058.15530-0.370503.153702.53480K562AQR
UBE2NENSG00000177889.51733.417902474.47860-0.5135011.814109.80950K562BCLAF1
UBE2NENSG00000177889.51631.260002732.33500-0.744104.816903.65440K562BOP1
UBE2NENSG00000177889.52413.952503167.78580-0.392103.240001.67770K562BUD13
UBE2NENSG00000177889.51457.412302905.40490-0.995309.020007.58490K562CPSF6
UBE2NENSG00000177889.51531.199801877.26070-0.294003.315202.14250K562CSTF2
UBE2NENSG00000177889.51933.117102478.34060-0.358405.303303.58750K562DDX21
UBE2NENSG00000177889.53310.531003935.23800-0.249403.588902.85910K562DDX47
UBE2NENSG00000177889.52591.992302066.725200.326604.484903.33260K562DKC1
UBE2NENSG00000177889.51450.684102017.58130-0.475904.599603.40830K562EFTUD2
UBE2NENSG00000177889.52276.002803284.76950-0.5293011.4071010.09380K562EIF2S2
UBE2NENSG00000177889.51604.710702160.41500-0.429002.911001.84760K562EIF3D
UBE2NENSG00000177889.5987.268501624.50100-0.7185010.520708.89940K562EIF4A3
UBE2NENSG00000177889.53991.955704998.86050-0.324502.658501.73550K562EIF4G2
UBE2NENSG00000177889.51957.228102389.30810-0.287802.753101.49040K562EXOSC5
UBE2NENSG00000177889.52127.530102955.89240-0.474403.140102.22400K562FMR1
UBE2NENSG00000177889.51463.497402505.26030-0.775506.756905.26530K562FTO
UBE2NENSG00000177889.52903.052401689.407400.7810022.5558020.94490K562FXR1
UBE2NENSG00000177889.52206.662002599.83380-0.236602.497701.41940K562GLRX3
UBE2NENSG00000177889.51780.346002774.06570-0.639804.839503.79310K562GPKOW
UBE2NENSG00000177889.52187.243902696.19450-0.301803.038701.91090K562HNRNPA1
UBE2NENSG00000177889.51168.925302542.60930-1.1211015.1703013.85770K562HNRNPC
UBE2NENSG00000177889.51773.066202270.16330-0.356502.656301.54100K562HNRNPF
UBE2NENSG00000177889.53621.624402688.931300.429503.697802.60890K562HNRNPM
UBE2NENSG00000177889.53421.863004432.27200-0.373303.812202.88220K562HSPD1
UBE2NENSG00000177889.51444.096702368.39400-0.713704.774303.50770K562KRR1
UBE2NENSG00000177889.53045.171502283.321800.415305.343603.99450K562MBNL1
UBE2NENSG00000177889.51895.413302707.74740-0.514603.597702.59180K562METAP2
UBE2NENSG00000177889.52187.292102733.36560-0.321505.514604.39650K562MTPAP
UBE2NENSG00000177889.52047.117803037.13030-0.5691021.9418020.13470K562NSUN2
UBE2NENSG00000177889.52441.597903039.18260-0.315902.271901.51860K562PCBP3
UBE2NENSG00000177889.51854.019102482.07620-0.420903.696402.00970K562PHF6
UBE2NENSG00000177889.52469.568701963.333800.330902.806002.05150K562PRPF8
UBE2NENSG00000177889.51829.420402279.60710-0.317402.152501.36400K562PSIP1
UBE2NENSG00000177889.52808.413902248.307800.320803.409502.68120K562PTBP1
UBE2NENSG00000177889.54158.339801904.745301.1263026.6791024.98450K562PUS1
UBE2NENSG00000177889.52656.656701855.815300.517509.217508.15780K562RBM15
UBE2NENSG00000177889.52603.050002996.70050-0.203202.057901.34730K562SF3A3
UBE2NENSG00000177889.51944.815502637.80130-0.439703.006501.99150K562SF3B1
UBE2NENSG00000177889.51064.948101572.15630-0.562006.306604.40070K562SLBP
UBE2NENSG00000177889.52348.014503070.16880-0.386909.112907.52560K562SRPK2
UBE2NENSG00000177889.52838.984702204.077600.365104.236303.36890K562SRSF1
UBE2NENSG00000177889.51604.691502081.55140-0.375403.427802.23820K562SRSF5
UBE2NENSG00000177889.51767.834902211.64250-0.323104.262902.78980K562SRSF7
UBE2NENSG00000177889.51040.226001901.18660-0.8700011.301509.21100K562SUPV3L1
UBE2NENSG00000177889.53433.792102338.240100.554306.501605.23340K562SYNCRIP
UBE2NENSG00000177889.51561.332302230.69970-0.514705.545304.52620K562TARDBP
UBE2NENSG00000177889.51311.046901990.99960-0.602807.610104.94310K562TBRG4
UBE2NENSG00000177889.51615.754202151.75400-0.413304.875403.74270K562TIA1
UBE2NENSG00000177889.51521.105402192.66420-0.527604.578503.35020K562TIAL1
UBE2NENSG00000177889.51791.703902328.83870-0.378302.305701.45400K562TRIM56
UBE2NENSG00000177889.53055.736403824.21660-0.323602.720101.35250K562TRIP6
UBE2NENSG00000177889.51377.770402012.04420-0.546305.647804.14160K562UCHL5
UBE2NENSG00000177889.52271.979203220.32450-0.503308.086906.93730K562UPF1
UBE2NENSG00000177889.51974.948802755.54490-0.480506.661905.26810K562WDR3
UBE2NENSG00000177889.51457.956902048.62220-0.490704.665502.93910K562XRN2
UBE2NENSG00000177889.53027.804004572.14380-0.594606.234604.85330K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for UBE2N is not available on ENCORE database.





2 RBPs can affect the splicing of UBE2N :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEUBE2NENSG00000177889.5chr12-938045099380465093800980938038559380482893805075-0.128000.000000.00000excludedK562AQR
A3SSUBE2NENSG00000177889.5chr12-9380450993804756938045099380465093804828938050750.081000.000000.00000longerK562AQR
A5SSUBE2NENSG00000177889.5chr12-938048289380507593804901938050759380450993804650-0.087000.000000.00001shorterK562AQR
A5SSUBE2NENSG00000177889.5chr12-938048289380507593804901938050759380450993804650-0.068000.000390.04991shorterHepG2FTO

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for UBE2N is not avaliable on ENCORE database.