SOCS2

General Information

Gene Name       : SOCS2
Gene ID             : ENSG00000120833.13
Essential Gene : No

Functions

Localization

Domains (AlphaFold: SOCS2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878SOCS2ENSG00000120833.1311.868.1710.02ENCSR000AEF
HepG2SOCS2ENSG00000120833.131.572.291.93ENCSR985KAT
K562SOCS2ENSG00000120833.1388.27100.4394.35ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for SOCS2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • SOCS2 RNA is bound by 11 proteins.  







eCLIP assay for SOCS2 is not avaliable on ENCORE database.





11 proteins are bound to SOCS2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr129396879993968908+3'-UTR,CDS4.2012613.19940K562YBX3
chr129396650493966530+3'-UTR,5'-UTR3.064898.24506K562YBX3
chr129396927293969320+3'-UTR,CDS,intron-Distal,intron-Proximal3.920917.40140K562YBX3
chr129396867993968753+3'-UTR,CDS3.104995.58482K562YBX3
chr129396988193969927+3'-UTR,intron-Distal3.385114.21971K562TIA1
chr129396642793966530+3'-UTR,5'-UTR,intron-Proximal4.4418614.31693K562BUD13
chr129396872993968824+3'-UTR,CDS3.498084.54534K562IGF2BP2
chr129396862093968791+3'-UTR,CDS4.236705.22676K562IGF2BP1
chr129396647993966558+3'-UTR,5'-UTR3.032904.16286K562SRSF1
chr129396999393970070+3'-UTR,intron-Distal3.335773.73797K562CSTF2T
chr129396655893966642+3'-UTR,5'-UTR3.159833.01245K562SRSF1
chr129396977793969829+3'-UTR,intron-Distal4.443245.66560K562TIA1
chr129396666993966779+3'-UTR,5'-UTR,CDS4.003269.54304K562RBM15
chr129396942093969504+3'-UTR,CDS,intron-Distal3.687005.65632K562UPF1
chr129396642993966489+3'-UTR,5'-UTR,intron-Proximal4.253896.48405K562AQR
chr129396655393966594+3'-UTR,5'-UTR3.404837.64771K562RBM15
chr129396949193969580+3'-UTR,intron-Distal3.183115.72056K562IGF2BP1
chr129396659493966651+3'-UTR,5'-UTR3.395185.63070K562RBM15
chr129396474893964790+5'-UTR,intron-Distal3.840933.30664K562NONO
chr129396503793965107+5'-UTR,intron-Distal,intron-Proximal3.221463.84725K562NONO
chr129396686893966936+CDS,intron-Distal,intron-Proximal3.777433.37414K562CSTF2T
chr129396681193966888+CDS,intron-Proximal4.4551113.11100K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for SOCS2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for SOCS2 is not available on ENCORE database.

  • 137 RBPs can affect the levels of SOCS2.  








The Knockdown/knockout RNA-Seq assay for SOCS2 is not available on ENCORE database.





137 RBPs can affect the gene expression of SOCS2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
SOCS2ENSG00000120833.980.0510017.242602.214807.667005.98900HepG2AATF
SOCS2ENSG00000120833.9152.0597024.492202.6341020.4617019.15020HepG2ACO1
SOCS2ENSG00000120833.986.3454016.466002.390507.674106.83500HepG2AKAP1
SOCS2ENSG00000120833.946.9607011.199802.067904.614603.28170HepG2AKAP8
SOCS2ENSG00000120833.9114.9068048.820701.234805.605404.68790HepG2AUH
SOCS2ENSG00000120833.9106.4236057.001200.900702.170701.34430HepG2BCCIP
SOCS2ENSG00000120833.9281.3072067.166502.0662017.2822015.05100HepG2CCAR1
SOCS2ENSG00000120833.9114.1453024.491302.220409.525408.43670HepG2CKAP4
SOCS2ENSG00000120833.922.0173046.01900-1.063601.970501.32880HepG2DAZAP1
SOCS2ENSG00000120833.9196.1229019.070803.3622028.3030026.46690HepG2DDX21
SOCS2ENSG00000120833.962.6775015.778801.989905.145604.31630HepG2DDX3X
SOCS2ENSG00000120833.9437.8917056.031302.9662037.8500035.53900HepG2DDX55
SOCS2ENSG00000120833.928.90940125.33870-2.116202.257601.37760HepG2DDX59
SOCS2ENSG00000120833.946.9665013.541001.794203.518202.82910HepG2DDX6
SOCS2ENSG00000120833.911.0395031.12660-1.495502.232401.35270HepG2DHX30
SOCS2ENSG00000120833.9137.5882032.579602.078209.541007.95610HepG2EEF2
SOCS2ENSG00000120833.975.2957027.157001.471104.223602.85070HepG2EFTUD2
SOCS2ENSG00000120833.9239.1380026.445603.1766029.1238026.56680HepG2EIF3D
SOCS2ENSG00000120833.993.0930014.014702.731609.793208.53810HepG2EIF4B
SOCS2ENSG00000120833.9456.1086056.036903.0248039.8485038.06570HepG2ETF1
SOCS2ENSG00000120833.9108.0092023.937202.173703.480302.54140HepG2EWSR1
SOCS2ENSG00000120833.9757.8228022.867505.0504093.0998089.82680HepG2FIP1L1
SOCS2ENSG00000120833.9122.0167025.146502.2785011.365409.33290HepG2FUS
SOCS2ENSG00000120833.9131.5793014.516303.1801018.0991016.50660HepG2FXR1
SOCS2ENSG00000120833.935.1670013.476201.383702.171401.57930HepG2G3BP1
SOCS2ENSG00000120833.9163.3613023.545902.7944015.6267013.67690HepG2GEMIN5
SOCS2ENSG00000120833.994.9545026.932001.817806.688104.96040HepG2GRSF1
SOCS2ENSG00000120833.9564.2510032.582404.1141018.5425017.11000HepG2HNRNPA1
SOCS2ENSG00000120833.9100.0045036.240601.464304.925804.02050HepG2HNRNPC
SOCS2ENSG00000120833.951.31330142.94200-1.478008.611507.43660HepG2HNRNPF
SOCS2ENSG00000120833.9155.4862015.772803.3012023.6860021.43810HepG2HNRNPM
SOCS2ENSG00000120833.929.76440140.75750-2.2416014.1947012.68930HepG2IGF2BP1
SOCS2ENSG00000120833.954.9197013.701902.002804.850003.97850HepG2IGF2BP2
SOCS2ENSG00000120833.985.5686012.844002.735906.616905.13420HepG2IGF2BP3
SOCS2ENSG00000120833.9254.8884070.815101.8476011.105109.43790HepG2LARP4
SOCS2ENSG00000120833.9109.4006032.579801.747508.008306.16940HepG2LARP7
SOCS2ENSG00000120833.968.3381014.521302.234405.685304.75750HepG2MAGOH
SOCS2ENSG00000120833.967.1341027.636301.280404.141902.21000HepG2MARK2
SOCS2ENSG00000120833.947.7035014.605701.707503.205102.53060HepG2MATR3
SOCS2ENSG00000120833.9146.2902027.676402.402009.669707.82770HepG2METAP2
SOCS2ENSG00000120833.9221.0471018.499803.5787019.5704017.67270HepG2MSI2
SOCS2ENSG00000120833.958.2011014.952301.960604.838804.01480HepG2NCBP2
SOCS2ENSG00000120833.9124.9237045.633201.452807.775206.51310HepG2NOL12
SOCS2ENSG00000120833.9175.1671051.387001.769202.489701.45800HepG2NONO
SOCS2ENSG00000120833.95.48860105.87920-4.269804.412703.47250HepG2NSUN2
SOCS2ENSG00000120833.9100.2044026.593901.913707.116805.64610HepG2PABPC1
SOCS2ENSG00000120833.944.4129013.327901.736403.589402.77370HepG2PABPC4
SOCS2ENSG00000120833.968.5479035.636600.943702.369301.58030HepG2PARN
SOCS2ENSG00000120833.967.0300023.806801.493304.175902.91660HepG2PCBP2
SOCS2ENSG00000120833.97.5338044.09800-2.549306.210705.10310HepG2PRPF4
SOCS2ENSG00000120833.976.8183025.028701.617804.810903.24060HepG2PRPF6
SOCS2ENSG00000120833.9169.3762043.292501.9679012.7339011.17700HepG2PRPF8
SOCS2ENSG00000120833.9118.6980037.264301.671306.139303.54140HepG2PSIP1
SOCS2ENSG00000120833.9139.9163015.285503.1942023.0769021.78740HepG2PTBP1
SOCS2ENSG00000120833.9117.9801046.214501.352006.163905.17640HepG2PUM2
SOCS2ENSG00000120833.957.4553024.947601.203402.990202.35640HepG2PUS1
SOCS2ENSG00000120833.979.9766022.979901.799104.822303.90650HepG2RAVER1
SOCS2ENSG00000120833.9769.6339046.839804.03830124.62610122.22990HepG2RBM22
SOCS2ENSG00000120833.976.6567039.279200.964502.496401.55850HepG2RBM27
SOCS2ENSG00000120833.9140.4419031.895802.1384011.414909.30450HepG2RCC2
SOCS2ENSG00000120833.9179.4241017.004903.3992027.4513026.11060HepG2NELFE
SOCS2ENSG00000120833.977.3991015.849302.287806.767005.86470HepG2RECQL
SOCS2ENSG00000120833.95.8517022.56280-1.947002.286601.42590HepG2RPS10
SOCS2ENSG00000120833.9284.3852025.734503.4660037.0124035.21060HepG2RPS19
SOCS2ENSG00000120833.9178.0720036.237702.2968013.5987011.92270HepG2RPS2
SOCS2ENSG00000120833.977.5167036.978101.067702.992701.87440HepG2RPS5
SOCS2ENSG00000120833.980.3439042.832000.907402.583201.82120HepG2RRP9
SOCS2ENSG00000120833.9408.2090012.608405.0168011.204809.78670HepG2SF3A3
SOCS2ENSG00000120833.973.7253015.900502.213006.606305.75540HepG2SF3B4
SOCS2ENSG00000120833.970.3622017.566902.001803.597101.88840HepG2SFPQ
SOCS2ENSG00000120833.912.4299041.78260-1.749103.379402.61700HepG2SLBP
SOCS2ENSG00000120833.9179.0371037.390302.2594019.3363017.87040HepG2SMN1
SOCS2ENSG00000120833.918.01090131.56260-2.868803.064602.24130HepG2SNRNP70
SOCS2ENSG00000120833.9509.6923052.909603.2679075.8863074.18720HepG2SRFBP1
SOCS2ENSG00000120833.9290.1090016.602204.1270052.7367051.24670HepG2SRSF1
SOCS2ENSG00000120833.943.17530140.43420-1.7016010.249009.05630HepG2SRSF7
SOCS2ENSG00000120833.9396.3834048.920803.0183022.1160020.63060HepG2SUCLG1
SOCS2ENSG00000120833.9169.2329055.798201.600608.306207.23650HepG2SUPV3L1
SOCS2ENSG00000120833.9138.0147034.986901.9798011.9380011.02720HepG2TIAL1
SOCS2ENSG00000120833.98.4164035.29410-2.068204.213403.54600HepG2TRIM56
SOCS2ENSG00000120833.993.0045019.557302.249507.904106.84710HepG2U2AF1
SOCS2ENSG00000120833.9248.1785018.798603.7226016.3031013.77570HepG2U2AF2
SOCS2ENSG00000120833.969.8022011.181802.642003.939403.12910HepG2UPF1
SOCS2ENSG00000120833.9136.8025051.146801.419304.435403.14500HepG2UPF2
SOCS2ENSG00000120833.9457.2626010.795505.40440110.51520107.67330HepG2UTP3
SOCS2ENSG00000120833.9397.9633025.266203.9773052.8985049.52870HepG2XRCC6
SOCS2ENSG00000120833.9116.3777012.297703.2423020.6872019.53320HepG2ZNF622
SOCS2ENSG00000120833.91464.25550972.358100.590503.427502.09800K562AARS
SOCS2ENSG00000120833.9387.49320692.43180-0.837503.566201.60490K562ADAR
SOCS2ENSG00000120833.9748.90060972.46980-0.376904.053102.18950K562AKAP1
SOCS2ENSG00000120833.92778.518303537.15440-0.348303.179602.11120K562AKAP8
SOCS2ENSG00000120833.92738.937103349.63110-0.290402.680602.03770K562AKAP8L
SOCS2ENSG00000120833.91395.210701900.00060-0.445504.249903.55210K562AQR
SOCS2ENSG00000120833.92670.362203514.46750-0.396306.620805.12880K562ATP5C1
SOCS2ENSG00000120833.91230.49190988.964400.315103.149501.72940K562BCCIP
SOCS2ENSG00000120833.9752.74690955.70070-0.344403.588702.49030K562BCLAF1
SOCS2ENSG00000120833.9749.006901067.86930-0.511705.967703.74550K562CEBPZ
SOCS2ENSG00000120833.9845.688501576.67630-0.898706.818205.09650K562CNOT7
SOCS2ENSG00000120833.92241.599501825.344200.296303.893002.57250K562CPEB4
SOCS2ENSG00000120833.9795.546401091.50630-0.456304.497003.49830K562CPSF6
SOCS2ENSG00000120833.91055.67480740.585900.511303.576601.45140K562YBX3
SOCS2ENSG00000120833.91760.216702939.58450-0.7399015.5275013.37610K562CELF1
SOCS2ENSG00000120833.92692.992903776.95520-0.488005.924203.75110K562DDX19B
SOCS2ENSG00000120833.91463.24900837.968100.8041019.1347016.13150K562DDX27
SOCS2ENSG00000120833.91770.87930985.301000.8457016.0212013.42150K562DDX3X
SOCS2ENSG00000120833.93932.110001888.724501.0578048.7423046.36500K562DDX47
SOCS2ENSG00000120833.94193.203803604.781100.218002.350901.55310K562DKC1
SOCS2ENSG00000120833.93358.512801346.952701.3180040.7934038.67260K562EIF2S2
SOCS2ENSG00000120833.91107.63260689.700400.683304.202202.93730K562EIF3A
SOCS2ENSG00000120833.91591.76730869.701700.8719010.277208.10840K562EIF3D
SOCS2ENSG00000120833.91171.73470926.968300.338003.318002.02770K562EIF4B
SOCS2ENSG00000120833.9659.056201141.52190-0.792509.737107.38270K562EXOSC5
SOCS2ENSG00000120833.91298.62070977.107700.410303.420401.62870K562FASTKD2
SOCS2ENSG00000120833.91394.73960923.353900.594905.850804.09890K562FKBP4
SOCS2ENSG00000120833.91704.838701110.520600.618307.349805.92190K562FMR1
SOCS2ENSG00000120833.91293.16910971.097000.413104.678102.26770K562FUBP3
SOCS2ENSG00000120833.91302.935701070.490400.283402.679302.08240K562FXR1
SOCS2ENSG00000120833.91519.123701107.568200.455704.866202.90400K562G3BP1
SOCS2ENSG00000120833.91579.504901009.356800.645903.438602.63370K562G3BP2
SOCS2ENSG00000120833.9997.352401247.72860-0.323103.126001.91140K562GLRX3
SOCS2ENSG00000120833.9771.992201042.14520-0.432903.641402.73500K562GPKOW
SOCS2ENSG00000120833.92684.391801795.024200.580508.889207.51270K562GRSF1
SOCS2ENSG00000120833.91950.859601157.077300.753503.495102.08880K562HNRNPK
SOCS2ENSG00000120833.9999.448501706.90910-0.7722013.1283010.70980K562HNRNPL
SOCS2ENSG00000120833.92131.684101142.849900.8993012.5923010.22570K562HNRNPM
SOCS2ENSG00000120833.91050.787701343.25590-0.354303.791102.74320K562HNRNPU
SOCS2ENSG00000120833.95865.771401883.687001.6387057.1280054.37360K562HSPD1
SOCS2ENSG00000120833.9849.935101227.93510-0.530804.188001.91930K562IGF2BP1
SOCS2ENSG00000120833.91498.339801158.349600.371202.331701.41270K562IGF2BP2
SOCS2ENSG00000120833.91697.029201178.253300.526306.086704.21520K562IGF2BP3
SOCS2ENSG00000120833.92679.326503554.98480-0.408004.983303.81230K562KIF1C
SOCS2ENSG00000120833.91571.723701217.515600.368303.565102.60420K562MAGOH
SOCS2ENSG00000120833.9945.061701215.06620-0.362603.185502.19060K562MATR3
SOCS2ENSG00000120833.95411.165703982.454500.442205.803804.39980K562MBNL1
SOCS2ENSG00000120833.9821.313001017.23930-0.308702.123101.35490K562METAP2
SOCS2ENSG00000120833.91790.038801311.834800.448307.968206.66140K562MTPAP
SOCS2ENSG00000120833.91980.980802791.39560-0.494803.763502.69330K562NAA15
SOCS2ENSG00000120833.91822.347601027.925800.8260016.5664013.83420K562NCBP2
SOCS2ENSG00000120833.9717.737201457.50530-1.0220036.1467033.96410K562NSUN2
SOCS2ENSG00000120833.91934.569401067.382700.8578011.200307.86770K562PABPC4
SOCS2ENSG00000120833.91726.887601190.053900.537007.456305.17290K562PCBP1
SOCS2ENSG00000120833.9922.408301452.01000-0.654606.803205.49690K562PCBP3
SOCS2ENSG00000120833.92005.291401329.166100.593206.401803.92670K562PKM
SOCS2ENSG00000120833.9787.031601113.72920-0.500905.490104.36250K562POLR2G
SOCS2ENSG00000120833.91746.21580790.397101.1435021.2866019.20810K562PRPF8
SOCS2ENSG00000120833.92191.439101182.882500.8895019.5778017.88360K562PTBP1
SOCS2ENSG00000120833.92100.424902608.90820-0.312802.569701.78430K562PUF60
SOCS2ENSG00000120833.92271.051702774.58320-0.288902.678201.63120K562PUM1
SOCS2ENSG00000120833.93525.325202718.950500.374606.819505.29150K562PUM2
SOCS2ENSG00000120833.94796.556303322.300800.529706.272405.49410K562PUS1
SOCS2ENSG00000120833.92130.21540963.137501.1451011.737908.86200K562RAVER1
SOCS2ENSG00000120833.91973.126003236.76190-0.7141017.9160016.37900K562RBM15
SOCS2ENSG00000120833.91680.68170957.808100.811104.604402.81940K562RBM25
SOCS2ENSG00000120833.91516.877901193.670100.345602.568401.52020K562NELFE
SOCS2ENSG00000120833.92142.77930805.140301.4121027.2687024.77030K562RPS19
SOCS2ENSG00000120833.94126.910601910.342701.111105.318703.48130K562SF1
SOCS2ENSG00000120833.9564.01160746.77010-0.404902.726901.47030K562SLBP
SOCS2ENSG00000120833.91185.70040838.694600.499404.716402.47610K562SND1
SOCS2ENSG00000120833.91138.29240825.160300.464004.137202.81060K562SRFBP1
SOCS2ENSG00000120833.9714.898801095.34580-0.615609.739307.52770K562SRSF7
SOCS2ENSG00000120833.91514.53820942.077900.684902.879301.57190K562SSB
SOCS2ENSG00000120833.9577.68920765.33230-0.405802.304301.38090K562SUPV3L1
SOCS2ENSG00000120833.9452.81610697.61470-0.623504.890502.70730K562TFIP11
SOCS2ENSG00000120833.91303.810301608.73940-0.303203.519902.08070K562TROVE2
SOCS2ENSG00000120833.91305.85140978.850900.415702.894801.77330K562U2AF1
SOCS2ENSG00000120833.91285.227401010.790700.346403.318102.44060K562U2AF2
SOCS2ENSG00000120833.92209.078901545.428600.5153011.4571010.11980K562UPF1
SOCS2ENSG00000120833.91902.937501368.836900.475203.895802.45890K562UTP3
SOCS2ENSG00000120833.92038.812301375.161900.5680014.2672012.53670K562WDR43
SOCS2ENSG00000120833.94510.852802235.713901.012606.602103.89060K562XPO5
SOCS2ENSG00000120833.91680.378602140.63280-0.349302.359401.57210K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for SOCS2 is not available on ENCORE database.





7 RBPs can affect the splicing of SOCS2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
RISOCS2ENSG00000120833.9chr12+9396646093969982939664609396681293968497939699820.188000.000000.00000includedK562PUS1
RISOCS2ENSG00000120833.9chr12+9396646093969982939664609396681293968497939699820.067000.000000.00000includedK562AKAP8L
RISOCS2ENSG00000120833.9chr12+9396646093969982939664609396681293968497939699820.059000.000000.00001includedK562RBM15
RISOCS2ENSG00000120833.9chr12+9396646093969982939664609396681293968497939699820.126000.007700.07989includedK562U2AF2
RISOCS2ENSG00000120833.9chr12+9396646093969982939664609396681293968497939699820.105000.000000.00000includedK562UTP18
RISOCS2ENSG00000120833.9chr12+9396646093969982939664609396681293968497939699820.078000.001030.00692includedK562AQR
RISOCS2ENSG00000120833.9chr12+939664609396998293966460939668129396849793969982-0.053000.007670.09140excludedK562FXR1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for SOCS2 is not avaliable on ENCORE database.