SLC22A3

General Information

Gene Name       : SLC22A3
Gene ID             : ENSG00000146477.5
Essential Gene : No

Functions

Localization

Domains (AlphaFold: SLC22A3)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878SLC22A3ENSG00000146477.50.000.000.00ENCSR000AEF
HepG2SLC22A3ENSG00000146477.514.4020.4617.43ENCSR985KAT
K562SLC22A3ENSG00000146477.50.000.000.00ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for SLC22A3 is not avaliable on ENCORE database.



Proteins bound to RNA
  • SLC22A3 RNA is bound by 24 proteins.  







eCLIP assay for SLC22A3 is not avaliable on ENCORE database.





24 proteins are bound to SLC22A3 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr6160769403160769465+5'-UTR,CDS3.416134.02244HepG2NCBP2
chr6160769407160769559+5'-UTR,CDS3.2513316.65948HepG2DDX3X
chr6160769316160769375+5'-UTR3.586754.41726HepG2NKRF
chr6160863891160863946+CDS,intron-Proximal4.819503.70131HepG2PRPF8
chr6160863797160863854+CDS4.023903.49905HepG2PPIG
chr6160828146160828235+CDS,intron-Proximal3.343606.28230HepG2PPIG
chr6160828072160828146+CDS,intron-Proximal3.663954.22917HepG2PPIG
chr6160819019160819122+CDS,intron-Proximal3.501358.34074HepG2PPIG
chr6160769829160769860+CDS3.767724.30502HepG2XRN2
chr6160769814160769863+CDS3.165886.15331HepG2NKRF
chr6160863788160863861+CDS,intron-Proximal4.484024.04372HepG2BCLAF1
chr6160775688160775796+intron-Distal4.448855.38422HepG2ILF3
chr6160789154160789238+intron-Distal4.445409.90411HepG2HNRNPK
chr6160795544160795594+intron-Distal3.664735.83578HepG2SUGP2
chr6160794076160794132+intron-Distal4.678575.94008HepG2HNRNPM
chr6160783639160783689+intron-Distal3.607894.45183HepG2CSTF2T
chr6160806220160806301+intron-Distal5.000485.72657HepG2MATR3
chr6160854560160854648+intron-Distal4.474758.08894HepG2QKI
chr6160789720160789775+intron-Distal3.146756.46897HepG2HNRNPL
chr6160783816160783912+intron-Distal3.101016.44311HepG2CSTF2T
chr6160794409160794453+intron-Distal3.729376.02668HepG2SUGP2
chr6160801504160801567+intron-Distal3.237003.51804HepG2HNRNPL
chr6160791881160791960+intron-Distal3.103624.00631HepG2PTBP1
chr6160794061160794116+intron-Distal4.648215.72657HepG2MATR3
chr6160793367160793413+intron-Distal4.506985.83842HepG2SUGP2
chr6160807032160807074+intron-Distal3.017284.21501HepG2MATR3
chr6160868566160868655+intron-Distal,intron-Proximal4.253913.48162HepG2TAF15
chr6160813104160813189+intron-Distal3.849593.06084HepG2HNRNPK
chr6160793286160793345+intron-Distal5.6241612.61003HepG2SUGP2
chr6160793737160793782+intron-Distal3.051284.77524HepG2SUGP2
chr6160820479160820533+intron-Distal4.060063.83958HepG2QKI
chr6160806903160806979+intron-Distal3.371538.80382HepG2SUGP2
chr6160820155160820221+intron-Distal4.511583.74583HepG2PTBP1
chr6160804349160804434+intron-Distal3.225695.10768HepG2QKI
chr6160807084160807156+intron-Distal3.500958.75882HepG2SUGP2
chr6160770018160770092+intron-Distal3.762205.64872HepG2NKRF
chr6160792045160792127+intron-Distal4.188583.53723HepG2PTBP1
chr6160784669160784708+intron-Distal3.203583.47356HepG2HNRNPK
chr6160846560160846612+intron-Distal3.453844.48652HepG2PTBP1
chr6160865429160865509+intron-Distal4.759728.21950HepG2CSTF2
chr6160770135160770191+intron-Distal3.303654.50064HepG2SFPQ
chr6160806326160806394+intron-Distal3.092893.84021HepG2HNRNPM
chr6160797388160797458+intron-Distal3.812406.28577HepG2FAM120A
chr6160819284160819368+intron-Distal4.5321611.18589HepG2U2AF2
chr6160792762160792816+intron-Distal3.950316.02877HepG2SUGP2
chr6160806141160806179+intron-Distal3.008053.95507HepG2SUGP2
chr6160792072160792179+intron-Distal4.249709.06128HepG2SUGP2
chr6160794467160794532+intron-Distal4.559913.97018HepG2HNRNPM
chr6160793501160793574+intron-Distal5.022017.87294HepG2MATR3
chr6160793084160793129+intron-Distal5.164736.88667HepG2SUGP2
chr6160850437160850528+intron-Distal4.383328.84799HepG2QKI
chr6160770206160770293+intron-Distal3.332633.11000HepG2HNRNPM
chr6160771058160771102+intron-Distal3.856886.29995HepG2HNRNPM
chr6160806417160806478+intron-Distal3.9410010.73957HepG2SUGP2
chr6160789153160789225+intron-Distal6.0696612.71401HepG2PCBP2
chr6160793723160793763+intron-Distal4.491315.37222HepG2MATR3
chr6160795048160795085+intron-Distal4.214504.36036HepG2SUGP2
chr6160770065160770117+intron-Distal3.932345.10890HepG2SFPQ
chr6160797380160797452+intron-Distal3.896055.53636HepG2GTF2F1
chr6160784617160784669+intron-Distal3.374764.39383HepG2HNRNPK
chr6160795234160795329+intron-Distal4.5724511.10994HepG2SUGP2
chr6160795247160795346+intron-Distal3.810955.95721HepG2MATR3
chr6160793505160793559+intron-Distal3.416396.55984HepG2SUGP2
chr6160792055160792157+intron-Distal3.473256.46496HepG2MATR3
chr6160807028160807075+intron-Distal4.958507.14375HepG2SUGP2
chr6160855532160855617+intron-Distal4.653604.85866HepG2QKI
chr6160820231160820354+intron-Distal4.469859.54872HepG2PTBP1
chr6160770996160771084+intron-Distal3.176596.78375HepG2SFPQ
chr6160806338160806392+intron-Distal3.749705.06177HepG2SUGP2
chr6160868681160868741+intron-Proximal4.229084.50924HepG2SF3B4
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for SLC22A3 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for SLC22A3 is not available on ENCORE database.

  • 110 RBPs can affect the levels of SLC22A3.  








The Knockdown/knockout RNA-Seq assay for SLC22A3 is not available on ENCORE database.





110 RBPs can affect the gene expression of SLC22A3 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
SLC22A3ENSG00000146477.4951.86970659.216400.529903.872302.77030HepG2ABCF1
SLC22A3ENSG00000146477.4369.61590712.55130-0.9470017.4246016.17740HepG2ACO1
SLC22A3ENSG00000146477.4946.92810456.358101.0530014.9103012.88430HepG2ADAR
SLC22A3ENSG00000146477.4269.57020937.40810-1.7980028.2860026.79790HepG2AKAP1
SLC22A3ENSG00000146477.4320.63000508.68010-0.665804.598803.26780HepG2AKAP8
SLC22A3ENSG00000146477.4902.46780595.130800.600606.195804.18510HepG2ATP5C1
SLC22A3ENSG00000146477.4431.36310974.01770-1.1750028.9000027.10710HepG2AUH
SLC22A3ENSG00000146477.4207.50230442.76870-1.0934010.748909.66990HepG2BOP1
SLC22A3ENSG00000146477.4659.52420494.039200.416703.250901.92170HepG2BUD13
SLC22A3ENSG00000146477.4461.66620630.29580-0.449202.245401.37600HepG2CCAR1
SLC22A3ENSG00000146477.42654.72890736.906001.8489053.3697050.71900HepG2CIRBP
SLC22A3ENSG00000146477.496.66370411.03710-2.0882010.111908.68230HepG2CNOT7
SLC22A3ENSG00000146477.4694.41490391.296000.827409.290107.50960HepG2CSTF2
SLC22A3ENSG00000146477.41073.67280659.015400.7041015.0986013.49470HepG2DDX19B
SLC22A3ENSG00000146477.4856.60730623.516200.458103.351302.60970HepG2DDX21
SLC22A3ENSG00000146477.41120.37740610.228500.8765013.9413011.97580HepG2DDX24
SLC22A3ENSG00000146477.4924.02950582.704700.665105.126503.43690HepG2DDX27
SLC22A3ENSG00000146477.4473.77040897.99150-0.9225010.170309.03770HepG2DDX3X
SLC22A3ENSG00000146477.4312.09680622.69270-0.996508.170706.92110HepG2DDX55
SLC22A3ENSG00000146477.4733.29960461.589100.667703.346902.27360HepG2DDX59
SLC22A3ENSG00000146477.4387.79590771.33330-0.992109.793808.70770HepG2DDX6
SLC22A3ENSG00000146477.41361.07140681.722800.9974026.0616024.50820HepG2DKC1
SLC22A3ENSG00000146477.4922.41810436.846401.0782013.7691011.95840HepG2EEF2
SLC22A3ENSG00000146477.4805.73310574.226100.488602.901301.76430HepG2AGO1
SLC22A3ENSG00000146477.4192.15370741.56090-1.9483032.3614030.49030HepG2EIF2S1
SLC22A3ENSG00000146477.4732.82720500.203200.550905.383903.78560HepG2EIF2S2
SLC22A3ENSG00000146477.4885.94220588.857000.589206.473904.92570HepG2EIF3G
SLC22A3ENSG00000146477.41502.57780819.540700.8745010.129308.92370HepG2EIF4A3
SLC22A3ENSG00000146477.41190.54600797.883000.577303.777102.97960HepG2EIF4B
SLC22A3ENSG00000146477.41646.52710927.571500.8278015.8077014.14670HepG2EIF4G1
SLC22A3ENSG00000146477.4936.68590571.160500.713607.971806.25290HepG2ESF1
SLC22A3ENSG00000146477.4873.48860696.304500.327002.320701.55650HepG2EWSR1
SLC22A3ENSG00000146477.4178.36300316.95250-0.829406.511504.69340HepG2FAM120A
SLC22A3ENSG00000146477.4427.82030594.22550-0.474003.450702.19460HepG2FASTKD2
SLC22A3ENSG00000146477.4226.71680665.68650-1.5540018.1704016.50520HepG2FIP1L1
SLC22A3ENSG00000146477.4729.69430421.662700.791109.045507.66490HepG2FUBP3
SLC22A3ENSG00000146477.4402.21440767.01960-0.931309.534908.33800HepG2G3BP1
SLC22A3ENSG00000146477.41730.50940814.229801.0876018.3460016.13050HepG2G3BP2
SLC22A3ENSG00000146477.4629.31300315.735700.9950010.449808.77810HepG2GEMIN5
SLC22A3ENSG00000146477.4411.11560638.15770-0.634404.725103.39240HepG2GNB2L1
SLC22A3ENSG00000146477.4667.18120460.757500.534003.386002.68260HepG2GPKOW
SLC22A3ENSG00000146477.4857.07520592.384800.532803.664001.49440HepG2GRWD1
SLC22A3ENSG00000146477.4486.35450729.81770-0.585503.165201.47690HepG2GTF2F1
SLC22A3ENSG00000146477.41485.41810463.970201.6787044.0363042.08870HepG2HNRNPA1
SLC22A3ENSG00000146477.4254.27030516.05230-1.021208.911707.72030HepG2HNRNPC
SLC22A3ENSG00000146477.4711.16340566.090800.329002.853702.12630HepG2HNRNPF
SLC22A3ENSG00000146477.4588.50120856.70580-0.541804.239603.41950HepG2HNRNPL
SLC22A3ENSG00000146477.4732.08180439.711000.735306.646205.71660HepG2HNRNPLL
SLC22A3ENSG00000146477.4221.69950512.64260-1.2093011.4632010.30010HepG2HNRNPU
SLC22A3ENSG00000146477.4901.16740553.860100.702205.463103.75840HepG2HSPD1
SLC22A3ENSG00000146477.4888.10530557.443700.671808.784307.56490HepG2IGF2BP1
SLC22A3ENSG00000146477.41706.74980779.674901.1302019.2220017.62250HepG2IGF2BP2
SLC22A3ENSG00000146477.4439.62130731.62560-0.734802.754601.77390HepG2IGF2BP3
SLC22A3ENSG00000146477.41023.57480665.188300.621704.512903.44150HepG2LARP4
SLC22A3ENSG00000146477.4395.92860625.18420-0.659005.811404.18250HepG2LARP7
SLC22A3ENSG00000146477.41379.36720827.083400.737808.186407.06960HepG2MAGOH
SLC22A3ENSG00000146477.41141.50370831.726700.456703.082302.41950HepG2MATR3
SLC22A3ENSG00000146477.4215.26030371.13010-0.785803.720602.50610HepG2METAP2
SLC22A3ENSG00000146477.4381.19270538.92210-0.499603.166802.30400HepG2MSI2
SLC22A3ENSG00000146477.4747.99290448.487900.737904.314003.09020HepG2MTPAP
SLC22A3ENSG00000146477.4494.06070851.33000-0.785007.451606.43640HepG2NCBP2
SLC22A3ENSG00000146477.4361.45920524.85280-0.538102.775401.34300HepG2NKRF
SLC22A3ENSG00000146477.4300.84820932.49140-1.6321024.8613022.75110HepG2NOL12
SLC22A3ENSG00000146477.4916.23680571.653800.680503.699702.42060HepG2NONO
SLC22A3ENSG00000146477.41232.31350389.901201.6601036.5687034.36820HepG2NSUN2
SLC22A3ENSG00000146477.4377.85350758.21780-1.0048011.067709.65080HepG2PABPC4
SLC22A3ENSG00000146477.4218.83630507.46430-1.2135010.982409.48320HepG2PARN
SLC22A3ENSG00000146477.41110.29290733.066100.598803.782602.57490HepG2PCBP2
SLC22A3ENSG00000146477.4632.32860457.241200.467604.272303.37660HepG2PPIL4
SLC22A3ENSG00000146477.4831.62380531.912100.644609.213007.92000HepG2PRPF4
SLC22A3ENSG00000146477.4765.18530480.508200.671106.031404.89040HepG2PRPF8
SLC22A3ENSG00000146477.4576.04670702.18810-0.285701.908101.43750HepG2PTBP1
SLC22A3ENSG00000146477.4638.19940890.08170-0.479904.621303.87410HepG2PUF60
SLC22A3ENSG00000146477.4744.50600944.78720-0.343702.896002.29290HepG2PUM1
SLC22A3ENSG00000146477.4604.61990944.14290-0.643006.423505.41810HepG2PUM2
SLC22A3ENSG00000146477.41337.50570725.782100.8818023.6489022.17560HepG2PUS1
SLC22A3ENSG00000146477.4470.16670760.51530-0.693808.356307.35900HepG2QKI
SLC22A3ENSG00000146477.4475.82500734.67710-0.626707.055605.77260HepG2RBM15
SLC22A3ENSG00000146477.4283.07030934.72530-1.7234046.3393044.71630HepG2RBM22
SLC22A3ENSG00000146477.4404.61440690.20590-0.770508.656307.51230HepG2RBM25
SLC22A3ENSG00000146477.41036.88880612.172800.760207.014105.33360HepG2RCC2
SLC22A3ENSG00000146477.41078.90630727.821400.567808.324807.34080HepG2RECQL
SLC22A3ENSG00000146477.41034.32600694.929600.573703.376502.33330HepG2RPS10
SLC22A3ENSG00000146477.4175.80070345.06420-0.972908.215007.22230HepG2RPS19
SLC22A3ENSG00000146477.4454.84520695.27190-0.612204.860903.81840HepG2RPS2
SLC22A3ENSG00000146477.4769.79610412.370000.900407.487506.18780HepG2RPS3A
SLC22A3ENSG00000146477.4928.06990475.514100.964602.873301.48820HepG2SF1
SLC22A3ENSG00000146477.4778.73890435.216500.839309.274008.05750HepG2SF3B1
SLC22A3ENSG00000146477.41258.45690853.298000.560409.939008.73770HepG2SLBP
SLC22A3ENSG00000146477.4340.62200690.23970-1.018904.909402.83160HepG2SLTM
SLC22A3ENSG00000146477.4424.00600721.41890-0.766805.723504.30960HepG2SMNDC1
SLC22A3ENSG00000146477.4755.875801055.71950-0.482007.160206.45790HepG2SRFBP1
SLC22A3ENSG00000146477.4736.56250620.807800.246601.807401.34390HepG2SRSF9
SLC22A3ENSG00000146477.43180.27630916.582401.79470123.75490121.71070HepG2SSB
SLC22A3ENSG00000146477.4725.96640999.44240-0.461203.603102.91120HepG2SUCLG1
SLC22A3ENSG00000146477.4959.72030619.924800.630405.455304.55630HepG2SUPV3L1
SLC22A3ENSG00000146477.4944.13140685.870100.461003.952503.30140HepG2TAF15
SLC22A3ENSG00000146477.4607.46500428.630400.503003.494202.69050HepG2TARDBP
SLC22A3ENSG00000146477.4935.97360542.035700.788003.708502.48190HepG2TBRG4
SLC22A3ENSG00000146477.4299.10950415.54060-0.474302.368601.44030HepG2TFIP11
SLC22A3ENSG00000146477.4438.65070710.34390-0.695404.387902.56390HepG2TRA2A
SLC22A3ENSG00000146477.4709.37140502.574000.497105.660604.90650HepG2TRIM56
SLC22A3ENSG00000146477.4574.32960920.22150-0.680105.822604.57800HepG2UBE2L3
SLC22A3ENSG00000146477.4753.51600567.776800.408202.316901.40440HepG2UPF2
SLC22A3ENSG00000146477.4564.91400880.13810-0.639709.577408.57210HepG2UTP3
SLC22A3ENSG00000146477.4481.86330695.66760-0.529802.603401.38500HepG2XRCC5
SLC22A3ENSG00000146477.4508.27030777.97810-0.614103.779602.54000HepG2XRCC6
SLC22A3ENSG00000146477.41208.42810610.246700.9856013.5858011.99600HepG2XRN2
SLC22A3ENSG00000146477.4821.61580524.945200.6462010.048508.90190HepG2ZC3H8
SLC22A3ENSG00000146477.4570.584401002.61290-0.8133018.6295017.52390HepG2ZNF622
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for SLC22A3 is not available on ENCORE database.





2 RBPs can affect the splicing of SLC22A3 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SESLC22A3ENSG00000146477.4chr6+160846882160847108160831760160831878160857811160857909-0.163000.000010.00123excludedHepG2TBRG4
SESLC22A3ENSG00000146477.4chr6+1608655101608657311608646611608647741608687501608688500.187000.000060.00129includedHepG2U2AF2

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for SLC22A3 is not avaliable on ENCORE database.