NRAS

General Information

Gene Name       : NRAS
Gene ID             : ENSG00000213281.4
Essential Gene : No

Functions

Localization

Domains (AlphaFold: NRAS)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878NRASENSG00000213281.457.6145.6351.62ENCSR000AEF
HepG2NRASENSG00000213281.421.8549.8535.85ENCSR985KAT
K562NRASENSG00000213281.446.3650.7348.55ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for NRAS is not avaliable on ENCORE database.



Proteins bound to RNA
  • NRAS RNA is bound by 16 proteins.  







eCLIP assay for NRAS is not avaliable on ENCORE database.





16 proteins are bound to NRAS RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr1115250146115250191-3'-UTR,intron-Distal4.512383.98716K562IGF2BP1
chr1115248000115248040-3'-UTR,intron-Distal3.614647.68147K562FAM120A
chr1115250788115250813-3'-UTR,intron-Distal5.4293011.00359K562LIN28B
chr1115249670115249710-3'-UTR,intron-Distal3.476624.76828K562IGF2BP1
chr1115248426115248473-3'-UTR,intron-Distal4.1988010.12270K562FAM120A
chr1115249893115249935-3'-UTR,intron-Distal3.736465.78778K562IGF2BP1
chr1115249865115249898-3'-UTR,intron-Distal3.719797.26174K562FAM120A
chr1115247922115247964-3'-UTR,intron-Distal4.339494.77152K562IGF2BP1
chr1115250417115250472-3'-UTR,intron-Distal5.4579426.56125K562LIN28B
chr1115250028115250128-3'-UTR,intron-Distal3.261085.74374K562IGF2BP1
chr1115247274115247296-3'-UTR,intron-Distal4.802665.60103K562UPF1
chr1115248264115248310-3'-UTR,intron-Distal3.691296.36816K562YBX3
chr1115248069115248106-3'-UTR,intron-Distal3.364096.67761K562UPF1
chr1115250508115250569-3'-UTR,intron-Distal3.669358.91050K562YBX3
chr1115250495115250544-3'-UTR,intron-Distal3.705725.23915K562IGF2BP1
chr1115250246115250287-3'-UTR,intron-Distal4.465985.29045K562IGF2BP1
chr1115249488115249553-3'-UTR,intron-Distal3.1980824.91371K562PUM2
chr1115249463115249539-3'-UTR,intron-Distal4.7031618.01794K562IGF2BP2
chr1115250376115250408-3'-UTR,intron-Distal4.743173.98311K562IGF2BP1
chr1115249031115249075-3'-UTR,intron-Distal4.317536.74636K562UPF1
chr1115248335115248422-3'-UTR,intron-Distal4.723614.55369K562LIN28B
chr1115249445115249545-3'-UTR,intron-Distal3.5509213.34023K562FAM120A
chr1115249158115249225-3'-UTR,intron-Distal3.4762916.18067K562FAM120A
chr1115250563115250596-3'-UTR,intron-Distal4.113713.50232K562IGF2BP1
chr1115247964115248012-3'-UTR,intron-Distal3.730174.29472K562IGF2BP1
chr1115249907115249918-3'-UTR,intron-Distal3.699085.45588K562PUM2
chr1115248376115248481-3'-UTR,intron-Distal4.0377015.92201K562UPF1
chr1115251150115251156-3'-UTR,intron-Distal,intron-Proximal5.5345812.79926K562LIN28B
chr1115247480115247534-3'-UTR,intron-Distal3.373618.86739K562PUM2
chr1115251156115251218-3'-UTR,CDS,intron-Distal6.1631621.80419K562LIN28B
chr1115247140115247186-3'-UTR,intron-Distal3.392075.65859K562PUM2
chr1115248329115248376-3'-UTR,intron-Distal3.078936.54251K562UPF1
chr1115248592115248623-3'-UTR,intron-Distal3.892944.24288K562UPF1
chr1115249941115250000-3'-UTR,intron-Distal4.550576.02873K562TARDBP
chr1115250989115251156-3'-UTR,intron-Distal,intron-Proximal4.347437.44508K562PRPF8
chr1115247311115247390-3'-UTR,intron-Distal3.168097.90454K562LIN28B
chr1115247965115248018-3'-UTR,intron-Distal3.108797.73762K562PUM2
chr1115259415115259515-5'-UTR,intron-Distal,intron-Proximal3.260233.66774HepG2CSTF2
chr1115259451115259515-5'-UTR,intron-Distal,intron-Proximal3.221044.86139HepG2CSTF2T
chr1115259277115259367-5'-UTR,intron-Distal5.1583420.62771K562DDX3X
chr1115258769115258798-5'-UTR,CDS,intron-Distal3.582017.50590K562DDX3X
chr1115256571115256621-CDS,intron-Distal,intron-Proximal4.053615.99890HepG2U2AF2
chr1115252125115252193-CDS,intron-Distal,intron-Proximal4.708594.13847K562AQR
chr1115258625115258685-CDS,intron-Distal,intron-Proximal4.603888.96422HepG2PRPF8
chr1115253104115253218-intron-Distal4.501555.04769HepG2PTBP1
chr1115251002115251122-intron-Distal,intron-Proximal4.742496.09994K562KHSRP
chr1115253090115253133-intron-Distal4.029593.76275K562PTBP1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for NRAS is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for NRAS is not available on ENCORE database.

  • 106 RBPs can affect the levels of NRAS.  








The Knockdown/knockout RNA-Seq assay for NRAS is not available on ENCORE database.





106 RBPs can affect the gene expression of NRAS :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
NRASENSG00000213281.41464.411702895.97950-0.9837016.0847014.15500HepG2ABCF1
NRASENSG00000213281.42831.206802335.757800.277404.548003.80540HepG2ACO1
NRASENSG00000213281.41304.930602284.73650-0.8081012.3058010.41870HepG2ADAR
NRASENSG00000213281.45397.030803935.829900.455403.871503.25800HepG2AKAP1
NRASENSG00000213281.41980.065802346.81270-0.245203.000702.20550HepG2AKAP8L
NRASENSG00000213281.41498.223303256.63930-1.1201021.6949019.76830HepG2ASCC1
NRASENSG00000213281.41566.568502528.31430-0.690606.652305.16470HepG2BCCIP
NRASENSG00000213281.43513.346902944.504700.254702.432701.70610HepG2CALR
NRASENSG00000213281.42764.366003811.67980-0.463502.504701.58290HepG2CCAR1
NRASENSG00000213281.41740.199503094.00880-0.8302012.9767011.43540HepG2CIRBP
NRASENSG00000213281.41996.788502335.34740-0.226003.237902.52880HepG2CKAP4
NRASENSG00000213281.42272.512502866.85220-0.335202.782102.09360HepG2CPSF6
NRASENSG00000213281.4869.473201561.96300-0.8451012.1705010.19010HepG2CSTF2
NRASENSG00000213281.43651.159703108.999000.231802.440101.82880HepG2CELF1
NRASENSG00000213281.41871.108802160.28600-0.207302.640401.82350HepG2DDX19B
NRASENSG00000213281.41053.650401935.78600-0.877508.056906.96170HepG2DDX21
NRASENSG00000213281.41255.967201893.13530-0.592005.081803.83560HepG2DDX24
NRASENSG00000213281.41622.013302326.07980-0.520103.264501.87270HepG2DDX27
NRASENSG00000213281.45606.790903770.378700.572406.700705.76890HepG2DDX3X
NRASENSG00000213281.41137.346302234.71240-0.9744033.2892031.61370HepG2DKC1
NRASENSG00000213281.41820.419302280.23550-0.324906.202605.28250HepG2DNAJC2
NRASENSG00000213281.41192.630402047.12630-0.779505.762704.47130HepG2EEF2
NRASENSG00000213281.42397.963701781.579300.428602.346401.33370HepG2AGO1
NRASENSG00000213281.41007.722801827.25000-0.858609.430107.67430HepG2EIF3G
NRASENSG00000213281.42517.155303350.01180-0.412402.536301.87610HepG2EIF4B
NRASENSG00000213281.42905.097303298.07180-0.183002.395801.60880HepG2EIF4G1
NRASENSG00000213281.41531.679502508.79360-0.7119010.503308.58660HepG2ESF1
NRASENSG00000213281.42723.617303471.35040-0.350002.799002.10300HepG2FXR1
NRASENSG00000213281.42138.338903418.57400-0.676909.099707.47250HepG2G3BP2
NRASENSG00000213281.44131.864903249.922800.346302.623401.99730HepG2GPKOW
NRASENSG00000213281.43697.663602583.294800.517302.746301.38490HepG2HLTF
NRASENSG00000213281.4687.541602322.71150-1.7563057.6677055.51500HepG2HNRNPA1
NRASENSG00000213281.42204.643902781.75100-0.335405.137404.19750HepG2HNRNPF
NRASENSG00000213281.42509.551203045.73310-0.279404.970604.08720HepG2HNRNPL
NRASENSG00000213281.41870.185302566.46920-0.456609.623508.54670HepG2HNRNPU
NRASENSG00000213281.42000.616402739.24680-0.453306.265105.21950HepG2IGF2BP1
NRASENSG00000213281.42430.782703292.52420-0.437802.957301.91430HepG2KHSRP
NRASENSG00000213281.41877.747402135.23600-0.185402.295501.36470HepG2KIF1C
NRASENSG00000213281.42321.884203472.56000-0.580706.429905.44030HepG2MAGOH
NRASENSG00000213281.42271.988803492.07980-0.620106.514105.57830HepG2MATR3
NRASENSG00000213281.41817.447402749.93980-0.597507.644606.44300HepG2NSUN2
NRASENSG00000213281.42758.766101971.535500.484602.428401.60750HepG2PABPC1
NRASENSG00000213281.42162.587302540.41510-0.232302.838501.98060HepG2PARN
NRASENSG00000213281.41788.213602289.09240-0.356304.901503.94970HepG2PPIL4
NRASENSG00000213281.41101.041402026.99240-0.8805026.5383024.61650HepG2PRPF4
NRASENSG00000213281.42415.553103120.92040-0.369606.443605.67710HepG2PTBP1
NRASENSG00000213281.41556.403202379.13500-0.6122017.2640015.95990HepG2PUS1
NRASENSG00000213281.44208.642902464.530900.771905.553004.57520HepG2RAVER1
NRASENSG00000213281.43856.557703127.507100.302203.265802.34200HepG2RBM15
NRASENSG00000213281.45586.720503502.887600.6734020.3296019.19060HepG2RBM22
NRASENSG00000213281.43594.047503067.561600.228401.972901.39600HepG2RBM25
NRASENSG00000213281.41529.144602183.77360-0.514103.927002.66070HepG2RCC2
NRASENSG00000213281.41377.590203473.25800-1.3341069.9330068.11720HepG2NELFE
NRASENSG00000213281.41620.113003234.91640-0.9976042.0723040.24300HepG2RECQL
NRASENSG00000213281.41946.400402285.57790-0.231803.167502.48790HepG2SAFB2
NRASENSG00000213281.41870.874303069.89360-0.7145011.4380010.09530HepG2SF3B1
NRASENSG00000213281.42310.346402665.40980-0.206203.268202.57850HepG2SMN1
NRASENSG00000213281.45774.378203956.430700.5454020.3133019.28220HepG2SRFBP1
NRASENSG00000213281.42406.148603391.50910-0.4952012.9946012.13370HepG2SRSF1
NRASENSG00000213281.42264.579702732.92230-0.271203.527302.75470HepG2SRSF7
NRASENSG00000213281.43302.710402759.193600.259304.099003.45230HepG2SRSF9
NRASENSG00000213281.4916.199903435.20250-1.90670140.49530138.36380HepG2SSB
NRASENSG00000213281.43140.310502303.046600.447302.492601.35510HepG2SUB1
NRASENSG00000213281.41088.014902474.68460-1.1855019.1971017.69160HepG2SUPV3L1
NRASENSG00000213281.42235.815303048.48610-0.447308.035907.16040HepG2TAF15
NRASENSG00000213281.41483.373302298.49800-0.631802.697801.64260HepG2TBRG4
NRASENSG00000213281.41959.452202493.95440-0.348004.230303.64000HepG2TIAL1
NRASENSG00000213281.41871.643902516.08750-0.426908.612507.70440HepG2TRIM56
NRASENSG00000213281.43639.677302501.652900.540806.533105.58280HepG2U2AF1
NRASENSG00000213281.41272.570202266.41800-0.832707.080005.43150HepG2UPF2
NRASENSG00000213281.42726.617402411.157300.177301.956901.43510HepG2UTP3
NRASENSG00000213281.43351.015302422.757200.467802.894601.60490HepG2XRCC5
NRASENSG00000213281.4801.260002436.05140-1.6042038.6083036.16250HepG2XRN2
NRASENSG00000213281.42485.440602000.386900.313105.674904.76550HepG2ZC3H8
NRASENSG00000213281.45231.275502746.678500.9294062.2721060.56850HepG2ZNF622
NRASENSG00000213281.43418.555906478.03160-0.9222014.4704011.84140K562ABCF1
NRASENSG00000213281.42740.121403731.21550-0.4454010.549509.53590K562AGGF1
NRASENSG00000213281.46536.373505435.559800.266002.190001.65780K562AQR
NRASENSG00000213281.41806.050102461.08800-0.446508.508605.18970K562ASCC1
NRASENSG00000213281.42717.510403281.67020-0.272103.538802.00950K562BCCIP
NRASENSG00000213281.42473.590503171.28410-0.358506.891205.34630K562BCLAF1
NRASENSG00000213281.43110.344705313.43430-0.7726014.7944012.32920K562CPEB4
NRASENSG00000213281.42894.970503963.21890-0.453106.769905.53480K562CPSF6
NRASENSG00000213281.41536.278202405.89160-0.6471013.2616010.75420K562CSTF2
NRASENSG00000213281.42840.497203338.34350-0.233003.191801.88430K562DDX21
NRASENSG00000213281.41968.399602704.06160-0.458108.278805.33030K562DDX24
NRASENSG00000213281.41892.182802943.84290-0.637607.111604.54220K562DDX51
NRASENSG00000213281.42000.923302821.34830-0.495703.407501.98230K562EEF2
NRASENSG00000213281.43241.346304168.94900-0.363102.229401.57310K562EIF2S2
NRASENSG00000213281.41813.944302401.09530-0.404605.762303.99930K562EIF4B
NRASENSG00000213281.43368.022204950.53990-0.555704.503102.37430K562ESF1
NRASENSG00000213281.41908.311202327.35340-0.286402.998801.63990K562EWSR1
NRASENSG00000213281.43731.331204656.25770-0.319503.079602.18210K562FIP1L1
NRASENSG00000213281.43906.670102772.766700.4945010.981109.86120K562FXR1
NRASENSG00000213281.43585.751102785.935700.364002.224801.60110K562G3BP2
NRASENSG00000213281.41648.484902733.17050-0.729409.447306.82730K562GEMIN5
NRASENSG00000213281.42151.680003376.14220-0.6499012.1683010.15590K562HNRNPA1
NRASENSG00000213281.45232.883603548.130000.560406.822204.80380K562HNRNPK
NRASENSG00000213281.42755.341503551.01020-0.366002.540501.57050K562IGF2BP2
NRASENSG00000213281.41849.104602705.77360-0.549203.996002.16680K562LIN28B
NRASENSG00000213281.42901.366003693.52340-0.348303.637602.62580K562METAP2
NRASENSG00000213281.48230.512906750.081300.286002.859001.34370K562NOL12
NRASENSG00000213281.42873.530503895.27190-0.4389015.9402014.35500K562NSUN2
NRASENSG00000213281.42753.656603699.46900-0.426003.790401.93310K562PKM
NRASENSG00000213281.42270.673902710.16820-0.255302.351901.61380K562POLR2G
NRASENSG00000213281.43865.677305285.47970-0.451305.274104.08270K562PPIG
NRASENSG00000213281.44580.145802652.909700.7877014.1388012.43230K562PRPF8
NRASENSG00000213281.41579.627002392.86170-0.599204.035802.91580K562PSIP1
NRASENSG00000213281.48869.738706733.974100.397305.324904.19600K562PUF60
NRASENSG00000213281.43113.245503850.74590-0.306702.700702.16220K562PUS1
NRASENSG00000213281.41627.444502182.43590-0.423302.728701.74510K562RCC2
NRASENSG00000213281.41717.744803660.41230-1.0915020.7693017.97240K562NELFE
NRASENSG00000213281.41672.520402829.34790-0.7584013.8345010.32500K562RECQL
NRASENSG00000213281.43327.175402702.577600.299902.202001.47670K562RPS19
NRASENSG00000213281.42905.424902414.733500.266802.341501.35140K562SAFB
NRASENSG00000213281.41988.974903555.49350-0.8380017.8188016.04560K562SRSF1
NRASENSG00000213281.41762.197102195.53360-0.317202.971701.87150K562SRSF4
NRASENSG00000213281.42624.157203357.54910-0.355602.936801.85060K562SRSF5
NRASENSG00000213281.42498.521202979.36600-0.253903.411202.10160K562SRSF7
NRASENSG00000213281.41400.753302569.10930-0.8751011.434609.33250K562SUPV3L1
NRASENSG00000213281.43340.635902718.328900.297303.356202.45270K562SYNCRIP
NRASENSG00000213281.42464.431303598.69310-0.546206.694705.55270K562TARDBP
NRASENSG00000213281.42782.225803471.26660-0.319203.504302.56610K562TIA1
NRASENSG00000213281.42755.523403405.63050-0.305602.681201.60870K562TRA2A
NRASENSG00000213281.44295.659505447.99170-0.342802.869801.45590K562TRIP6
NRASENSG00000213281.42218.643003534.12470-0.6717012.7819010.84590K562WDR3
NRASENSG00000213281.44360.824903674.944000.246802.379801.59050K562WDR43
NRASENSG00000213281.41763.160302768.11500-0.650708.116605.74700K562XRN2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for NRAS is not available on ENCORE database.





3 RBPs can affect the splicing of NRAS :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SENRASENSG00000213281.4chr1-115256420115256588115252189115252349115258670115258798-0.079000.002700.04641excludedK562SRSF1
SENRASENSG00000213281.4chr1-115256420115256599115252189115252349115258670115258798-0.052000.000270.04153excludedK562RBM22
A3SSNRASENSG00000213281.4chr1-1152507741152509051152507741152508131152511511152513980.096000.000000.00000longerK562AQR
A5SSNRASENSG00000213281.4chr1-115251151115251398115251248115251398115250774115250813-0.073000.001080.01980shorterK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for NRAS is not avaliable on ENCORE database.