MECOM

General Information

Gene Name       : MECOM
Gene ID             : ENSG00000085276.17
Essential Gene : No

Functions

Localization

Domains (AlphaFold: MECOM)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878MECOMENSG00000085276.170.000.000.00ENCSR000AEF
HepG2MECOMENSG00000085276.170.030.040.04ENCSR985KAT
K562MECOMENSG00000085276.1714.4716.6315.55ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for MECOM is not avaliable on ENCORE database.



Proteins bound to RNA
  • MECOM RNA is bound by 1 proteins.  







eCLIP assay for MECOM is not avaliable on ENCORE database.





1 proteins are bound to MECOM RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr3168842121168842184-intron-Distal4.428283.91475K562PTBP1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for MECOM is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for MECOM is not available on ENCORE database.

  • 123 RBPs can affect the levels of MECOM.  








The Knockdown/knockout RNA-Seq assay for MECOM is not available on ENCORE database.





123 RBPs can affect the gene expression of MECOM :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
MECOMENSG00000085276.1334.666706.017102.526304.119502.83740HepG2AATF
MECOMENSG00000085276.1331.8416011.418901.479402.358901.79030HepG2ACO1
MECOMENSG00000085276.1373.660201.791205.3617014.4150013.29940HepG2AKAP1
MECOMENSG00000085276.1373.0611038.034300.941702.378501.73340HepG2AUH
MECOMENSG00000085276.1339.7361011.036101.848102.856001.94260HepG2BCLAF1
MECOMENSG00000085276.1334.248907.738902.145802.976101.83260HepG2CPSF7
MECOMENSG00000085276.1356.2792012.491102.171604.303503.36200HepG2DDX55
MECOMENSG00000085276.1313.455101.416303.247802.307701.76240HepG2EIF2S1
MECOMENSG00000085276.1357.115605.575603.356608.668007.15480HepG2EIF3D
MECOMENSG00000085276.1355.238301.524705.179008.763907.57590HepG2EIF4B
MECOMENSG00000085276.1312.3373043.67530-1.823804.148103.43780HepG2ETF1
MECOMENSG00000085276.13124.670209.488403.7157016.1597014.55810HepG2FIP1L1
MECOMENSG00000085276.131.1341032.72760-4.850905.412103.99660HepG2FTO
MECOMENSG00000085276.1351.1333010.302602.311205.715004.15230HepG2FUS
MECOMENSG00000085276.1327.994401.580904.146205.639704.67420HepG2FXR1
MECOMENSG00000085276.132.5975037.04260-3.834006.587805.62800HepG2GPKOW
MECOMENSG00000085276.13154.9915014.535003.4145013.1908010.84350HepG2GRSF1
MECOMENSG00000085276.1339.4059012.651901.639002.973902.00990HepG2HNRNPA2B1
MECOMENSG00000085276.1314.2771055.57830-1.960805.244504.29650HepG2HNRNPF
MECOMENSG00000085276.1312.386501.486703.058501.933001.34360HepG2HNRNPK
MECOMENSG00000085276.135.3822035.35010-2.715504.412003.63330HepG2HNRNPLL
MECOMENSG00000085276.138.5594054.72990-2.676807.297006.17310HepG2IGF2BP1
MECOMENSG00000085276.1383.404301.399105.8974014.4326012.39970HepG2IGF2BP3
MECOMENSG00000085276.1344.8215017.719301.338802.314901.55970HepG2LARP4
MECOMENSG00000085276.1345.1685010.825702.060804.252702.83980HepG2LARP7
MECOMENSG00000085276.1349.753305.833703.092205.154203.74690HepG2METAP2
MECOMENSG00000085276.138.5970036.04450-2.067902.993501.98120HepG2MTPAP
MECOMENSG00000085276.1355.794501.627005.099705.425304.55260HepG2NCBP2
MECOMENSG00000085276.1339.6071011.475701.787102.607501.54860HepG2NONO
MECOMENSG00000085276.131.1044031.34200-4.826706.023904.94500HepG2NSUN2
MECOMENSG00000085276.13104.9372016.092502.705009.073807.68100HepG2PARN
MECOMENSG00000085276.131.5998014.50330-3.180402.762102.02570HepG2PPIL4
MECOMENSG00000085276.130.8935016.18230-4.178703.859802.95940HepG2PRPF4
MECOMENSG00000085276.1361.897902.160704.8402015.2121014.12880HepG2PTBP1
MECOMENSG00000085276.1344.4284013.832401.683303.646802.98560HepG2PUM1
MECOMENSG00000085276.13487.395009.409805.6947048.0935045.59190HepG2RAVER1
MECOMENSG00000085276.13134.2819036.503001.8791010.201509.34700HepG2RBM22
MECOMENSG00000085276.1317.277302.403402.845702.585902.05960HepG2NELFE
MECOMENSG00000085276.13131.8977059.854001.139805.107604.21730HepG2RPLP0
MECOMENSG00000085276.1353.879705.427503.311303.960303.23750HepG2RPS19
MECOMENSG00000085276.13169.013809.525504.1491026.0766024.14830HepG2RRP9
MECOMENSG00000085276.138.8097034.99170-1.989802.952902.22360HepG2SF3B1
MECOMENSG00000085276.1318.845102.246803.068102.456901.89500HepG2SF3B4
MECOMENSG00000085276.1351.9722016.883201.622003.970103.22220HepG2SMN1
MECOMENSG00000085276.138.5626038.93370-2.184903.560202.66940HepG2SNRNP70
MECOMENSG00000085276.13167.3229041.226302.0209013.9567013.06210HepG2SRFBP1
MECOMENSG00000085276.1328.948202.346303.624905.267804.66840HepG2SRSF1
MECOMENSG00000085276.1352.9625012.865202.041405.393904.56150HepG2SRSF5
MECOMENSG00000085276.130.0000035.78990-99999.9999911.1823010.28560HepG2SSB
MECOMENSG00000085276.1353.3909014.632801.867304.763003.98590HepG2SUCLG1
MECOMENSG00000085276.1328.128308.332401.755102.505801.55110HepG2TFIP11
MECOMENSG00000085276.133.8352015.79080-2.041701.797201.37610HepG2TIAL1
MECOMENSG00000085276.1357.822108.117002.832506.693405.72800HepG2U2AF1
MECOMENSG00000085276.130.0000012.23900-99999.999993.981103.11920HepG2XRN2
MECOMENSG00000085276.133.4623015.97240-2.205802.091101.49460HepG2ZC3H8
MECOMENSG00000085276.13384.704201169.75460-1.6044017.6892014.89480K562ABCF1
MECOMENSG00000085276.13133.94760284.22810-1.085404.610502.37520K562ADAR
MECOMENSG00000085276.13308.17610613.97400-0.9944010.290209.28570K562AGGF1
MECOMENSG00000085276.13192.64610334.44170-0.795807.111404.69850K562AKAP1
MECOMENSG00000085276.13390.69820674.58270-0.787908.916506.87050K562AKAP8
MECOMENSG00000085276.13362.67690638.84770-0.816804.755103.89170K562AKAP8L
MECOMENSG00000085276.131623.004201063.924800.609205.414003.59640K562APOBEC3C
MECOMENSG00000085276.13317.24550929.53890-1.5509011.5715010.49240K562AQR
MECOMENSG00000085276.13511.73780670.26690-0.389302.836201.91270K562ATP5C1
MECOMENSG00000085276.13274.63480533.17850-0.9571012.8745010.76660K562BCLAF1
MECOMENSG00000085276.13211.69010487.20700-1.2026012.4015010.51160K562BOP1
MECOMENSG00000085276.13509.22020814.71990-0.678005.446403.37740K562BUD13
MECOMENSG00000085276.13145.26870278.29690-0.937906.037304.31730K562CCAR1
MECOMENSG00000085276.13502.89970733.79810-0.545104.997703.37010K562CCDC124
MECOMENSG00000085276.13333.46560454.82980-0.447803.187701.55890K562CEBPZ
MECOMENSG00000085276.13323.83970552.58060-0.770907.209705.23210K562CIRBP
MECOMENSG00000085276.13371.36020861.62860-1.214203.437101.80260K562CKAP4
MECOMENSG00000085276.13421.02350940.91850-1.160206.768505.05300K562CNOT7
MECOMENSG00000085276.13636.15460877.96160-0.464802.795001.68470K562CPEB4
MECOMENSG00000085276.13299.94250518.02790-0.788307.758006.43600K562CPSF6
MECOMENSG00000085276.13261.45410404.49530-0.629604.279702.92600K562CSTF2
MECOMENSG00000085276.13940.362501482.11880-0.656406.919005.39640K562CELF1
MECOMENSG00000085276.13395.26250522.79360-0.403403.136901.84150K562DDX21
MECOMENSG00000085276.13251.27200338.86210-0.431402.296401.35140K562DDX3X
MECOMENSG00000085276.131617.25270908.686500.8316021.0375019.39830K562DDX47
MECOMENSG00000085276.13204.15160311.52000-0.609703.469801.96100K562DHX30
MECOMENSG00000085276.13590.49320809.43840-0.455004.603603.70500K562EIF2S2
MECOMENSG00000085276.13717.12160498.100900.525705.560404.44630K562EIF3G
MECOMENSG00000085276.13532.00640893.87040-0.748603.416001.57030K562ESF1
MECOMENSG00000085276.13195.89680309.01930-0.657604.308502.64510K562EWSR1
MECOMENSG00000085276.13434.75560840.76090-0.951509.293907.63890K562FIP1L1
MECOMENSG00000085276.13208.86810405.88470-0.958507.500505.49210K562FKBP4
MECOMENSG00000085276.13352.52900527.10610-0.580403.969402.94120K562FMR1
MECOMENSG00000085276.13300.68740446.78090-0.571302.683601.78240K562FTO
MECOMENSG00000085276.13717.24460368.165000.9620015.1664013.86180K562FXR1
MECOMENSG00000085276.13482.07410357.463500.431402.003001.41390K562G3BP2
MECOMENSG00000085276.13296.72890636.61120-1.1013017.4423015.03200K562GLRX3
MECOMENSG00000085276.13265.69330494.57880-0.896405.441304.33280K562GPKOW
MECOMENSG00000085276.13653.736701078.76070-0.722607.375206.12710K562GRSF1
MECOMENSG00000085276.13272.12170406.50250-0.579003.784601.37960K562GRWD1
MECOMENSG00000085276.13282.50140550.44660-0.9623011.617109.64150K562HNRNPA1
MECOMENSG00000085276.13377.01540673.47770-0.837003.082501.77450K562HNRNPA2B1
MECOMENSG00000085276.13258.13970467.84930-0.857907.564806.62420K562HNRNPC
MECOMENSG00000085276.13302.70620417.70640-0.464602.542201.45450K562HNRNPF
MECOMENSG00000085276.13491.69470691.48400-0.491902.703701.78510K562HNRNPM
MECOMENSG00000085276.13722.942301139.96890-0.657005.209804.13390K562HSPD1
MECOMENSG00000085276.13322.15680523.04900-0.699205.058102.61410K562IGF2BP1
MECOMENSG00000085276.13269.85550515.80130-0.934607.603505.58590K562IGF2BP2
MECOMENSG00000085276.13390.45500524.54890-0.425902.828001.62040K562IGF2BP3
MECOMENSG00000085276.13452.68750678.04770-0.582905.501604.24980K562KIF1C
MECOMENSG00000085276.13123.72110422.33580-1.7713017.0345014.54850K562KRR1
MECOMENSG00000085276.13431.66540649.00120-0.588303.791202.46670K562MAK16
MECOMENSG00000085276.13710.74950540.728700.394302.960702.00230K562MATR3
MECOMENSG00000085276.13247.68770482.76850-0.962809.696507.98020K562METAP2
MECOMENSG00000085276.13411.33640669.31280-0.702408.711607.35220K562MTPAP
MECOMENSG00000085276.13363.95910532.40070-0.548702.933302.02110K562NAA15
MECOMENSG00000085276.13487.20140353.520000.462603.128901.82280K562NCBP2
MECOMENSG00000085276.13363.07440743.67170-1.0344021.3113019.52550K562NSUN2
MECOMENSG00000085276.13324.28710460.51390-0.506003.202101.63080K562NUSAP1
MECOMENSG00000085276.13288.06560589.42190-1.032904.387203.06500K562PABPN1
MECOMENSG00000085276.13520.43530403.424800.367302.362201.62270K562POLR2G
MECOMENSG00000085276.13541.08510954.35230-0.818706.541205.18430K562PPIG
MECOMENSG00000085276.13642.86250478.783500.425002.542701.82370K562PRPF8
MECOMENSG00000085276.131753.367201315.536600.414402.940802.09880K562PUF60
MECOMENSG00000085276.13968.822401398.94770-0.530005.281803.77030K562PUM1
MECOMENSG00000085276.13402.98060633.70580-0.653105.511304.77700K562PUS1
MECOMENSG00000085276.13349.20940617.33130-0.822007.521906.57360K562RBM15
MECOMENSG00000085276.13349.18470504.69890-0.531403.824602.82480K562RBM22
MECOMENSG00000085276.13363.80680725.19020-0.995204.506502.42870K562RBM39
MECOMENSG00000085276.13399.79770249.676500.679103.758802.56990K562RPS3
MECOMENSG00000085276.13508.45440721.36480-0.504603.463401.38610K562SAFB2
MECOMENSG00000085276.13519.76540359.412900.532103.784402.51280K562SAFB
MECOMENSG00000085276.13552.90880856.97860-0.632203.034501.43460K562SBDS
MECOMENSG00000085276.13282.09290539.22540-0.934703.572902.14940K562SF1
MECOMENSG00000085276.13430.16840733.80660-0.7705011.223209.66450K562SF3A3
MECOMENSG00000085276.13277.11890470.39970-0.763405.206903.85150K562SF3B1
MECOMENSG00000085276.13279.03970371.96670-0.414702.383601.59210K562SF3B4
MECOMENSG00000085276.13200.95710306.57590-0.609403.304101.90920K562SLBP
MECOMENSG00000085276.13509.67220880.06270-0.788004.318802.12140K562SMN1
MECOMENSG00000085276.13253.31280362.69110-0.517802.700301.69250K562SRFBP1
MECOMENSG00000085276.13863.73560516.141200.742709.262007.98010K562SRSF1
MECOMENSG00000085276.13283.57960466.58470-0.718407.566405.63320K562SRSF7
MECOMENSG00000085276.13707.219101009.08010-0.512803.524402.07980K562STAU1
MECOMENSG00000085276.13684.87410404.624300.759209.079107.58410K562SYNCRIP
MECOMENSG00000085276.13245.81990403.45690-0.714804.533203.31280K562TIAL1
MECOMENSG00000085276.13206.78040428.49570-1.051209.957207.89480K562TRIM56
MECOMENSG00000085276.13626.15420983.81480-0.651904.983303.00250K562TRIP6
MECOMENSG00000085276.13613.97290788.53050-0.361003.440702.64480K562UPF1
MECOMENSG00000085276.13387.10800709.57860-0.874208.966606.92620K562UTP3
MECOMENSG00000085276.13393.87170674.72130-0.776608.983207.37090K562WDR3
MECOMENSG00000085276.13892.60660701.627300.347203.746302.77160K562WDR43
MECOMENSG00000085276.13643.563801047.33240-0.702604.080702.99940K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for MECOM is not available on ENCORE database.





3 RBPs can affect the splicing of MECOM :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEMECOMENSG00000085276.13chr3-1688257131688257401688198471688200141688305741688306620.438000.001210.02447includedK562SRSF1
A3SSMECOMENSG00000085276.13chr3-168833170168834527168833170168833555168838843168838997-0.377000.000320.04124shorterK562FXR1
A3SSMECOMENSG00000085276.13chr3-1688107451688109081688107451688108901688128631688130330.205000.000500.00375longerK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for MECOM is not avaliable on ENCORE database.