KPNB1

General Information

Gene Name       : KPNB1
Gene ID             : ENSG00000108424.9
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: KPNB1)


Antibody Validation

 View validation images for all KPNB1 antibodies

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878KPNB1ENSG00000108424.9280.79292.68286.74ENCSR000AEF
HepG2KPNB1ENSG00000108424.9318.69385.68352.19ENCSR985KAT
K562KPNB1ENSG00000108424.9381.11346.23363.67ENCSR000AEO

Assays

2 Released experiments are available on ENCORE database.

Assay TypeExp_NameENCODE IDTarget labelBiosampleStatusLinked AntibodyControlsMethodNote
knockdown followed by RNA-seq KPNB1-BGKcLV13-K562ENCSR667FZFKPNB1K562ReleasedENCSR712CQC   CRISPRKD% = 82.4,84.8
knockdown followed by RNA-seq KPNB1-BGHcLV14-HepG2ENCSR977NJBKPNB1HepG2ReleasedENCSR750CPT   CRISPRKD% = 77.4,70.8






  eCLIP  

No eCLIP experiment available



  Antibody Validation  
  GeneName    Antibody_DCC_ID    Product_ID    Lot_ID    Phosphate    HepG2 Primary Validation    K562 Primary Validation    HepG2 Secondary Validation    K562 Secondary Validation  
KPNB1ENCAB340RAJMA3-070SJ259850Released, ENCODE4BGHcLV14-47, Released, ENCODE4BGKcLV13-45, Released, ENCODE4
KPNB160769S1Submitted, ENCORE2BGHcLV14-47, Released, ENCODE4BGKcLV13-45, Submitted, ENCORE2
KPNB151186S1Submitted, ENCORE2BGHcLV14-47, Released, ENCODE4


  KD RNA-Seq  
  GeneName    Cell_Line    Method    Exp_ID    Control_ID    Sample_reps    Control_reps    KD%    Status    Project    Note  
KPNB1K562CRISPRENCSR667FZFENCSR712CQCKPNB1-BGKcLV13-45,KPNB1-BGKcLV13-46NT-BGKcLV13-1,NT-BGKcLV13-282.4,84.8ReleasedENCODE4
KPNB1K562CRISPRBGKcLV13-47,BGKcLV13-48BGKcLV13-1,BGKcLV13-277.9,66.4NotSatisfiedENCODE4
KPNB1HepG2CRISPRBGHcLV14-45,BGHcLV14-46BGHcLV14-1,BGHcLV14-280.1,68.5NotSatisfiedENCODE4
KPNB1HepG2CRISPRENCSR977NJBENCSR750CPTKPNB1-BGHcLV14-47,KPNB1-BGHcLV14-48NT-BGHcLV14-1,NT-BGHcLV14-277.4,70.8ReleasedENCODE4


  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela
KPNB1Product_ID: MA3-070
Lot_ID: SJ259850
Source: Thermo Fisher
Target Name: KPNB1-human		 KPNB1-HEPG2-CRISPR.png<br>Caption: Western blot following CRISPR against KPNB1 in HepG2 whole cell lysate using KPNB1 specific antibody. Lane 1 is a ladder, lane 2 is HepG2 non-targeting control knockdown, lane 3 and 4 are two different CRISPR against KPNB1. KPNB1 protein appears as the green arrow, GAPDH serves as a control and appears in red arrow.
 ThermoFisher_MA3-070_SL259850_KPNB1.png<br>Caption: IP-WB analysis of K562 whole cell lysate using the KPNB1 specific antibody, MA3-070. Lanes 1 and 3 are 2.5% of five million whole cell lysate input. Lanes 2 and 4 are 50% of IP enrichment from five million whole cell lysate using normal IgG antibody and the KPNB1-specific antibody, MA3-070. The same antibody was used to detect protein levels via Western blot. This antibody passes preliminary validation and will be further pursued for secondary validation. *NOTE* Protein sizes are taken from Genecards.org and are only estimates based on sequence. Actual protein size may differ based on protein characteristics and electrophoresis method used.
 KPNB1-K562-CRISPR.png<br>Caption: Western blot following CRISPR against KPNB1 in K562 whole cell lysate using KPNB1 specific antibody. Lane 1 is a ladder, lane 2 is K562 non-targeting control knockdown, lane 3 and 4 are two different CRISPR against KPNB1. KPNB1 protein appears as the green arrow, GAPDH serves as a control and appears in red arrow.
KPNB1Product_ID: 51186S
Lot_ID: 1
Source: Cell Signaling Technology
Target Name: KPNB1-human		 CST_51186S_1_KPNB1.png<br>Caption: IP-WB analysis of 51186S whole cell lysate using the KPNB1 specific antibody, 51186S. Lanes 1 and 2 are 2.5% of five million whole cell lysate input and 50% of IP enrichment, respectively, using a normal IgG antibody. Lane 3 is 50% of IP enrichment from five million whole cell lysate using the KPNB1-specific antibody, 51186S. The same antibody was used to detect protein levels via Western blot. This antibody passes preliminary validation and will be further pursued for secondary validation. *NOTE* Protein sizes are taken from Genecards.org and are only estimates based on sequence. Actual protein size may differ based on protein characteristics and electrophoresis method used.
KPNB1Product_ID: 60769S
Lot_ID: 1
Source: Cell Signaling Technology
Target Name: KPNB1-human		 CST_60769S_1_KPNB1.png<br>Caption: IP-WB analysis of 60769S whole cell lysate using the KPNB1 specific antibody, 60769S. Lanes 1 and 2 are 2.5% of five million whole cell lysate input and 50% of IP enrichment, respectively, using a normal IgG antibody. Lane 3 is 50% of IP enrichment from five million whole cell lysate using the KPNB1-specific antibody, 60769S. The same antibody was used to detect protein levels via Western blot. This antibody passes preliminary validation and will be further pursued for secondary validation. *NOTE* Protein sizes are taken from Genecards.org and are only estimates based on sequence. Actual protein size may differ based on protein characteristics and electrophoresis method used.
 KPNB1-K562-60769S.png<br>Caption: Western blot following CRISPR against KPNB1 in K562 whole cell lysate using KPNB1 specific antibody. Lane 1 is a ladder, lane 2 is K562 non-targeting control knockdown, lane 3 and 4 are two different CRISPR against KPNB1. KPNB1 protein appears as the green arrow, Beta-actin serves as a control and appears in red arrow.








RNA Targets

  • eCLIP assay for KPNB1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • KPNB1 RNA is bound by 56 proteins.  







eCLIP assay for KPNB1 is not avaliable on ENCORE database.





56 proteins are bound to KPNB1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr174576064645760700+3'-UTR,intron-Distal3.828908.06079K562IGF2BP2
chr174576055645760598+3'-UTR,intron-Distal3.0079423.06985K562PABPC4
chr174576004645760105+3'-UTR5.384087.16913K562LIN28B
chr174576010145760171+3'-UTR,intron-Proximal3.057505.99201HepG2UPF1
chr174575979845759807+3'-UTR3.3404519.27282K562YBX3
chr174576120345761229+3'-UTR,intron-Distal3.280556.48512K562FAM120A
chr174575977145759822+3'-UTR3.168937.20736HepG2G3BP1
chr174576026845760297+3'-UTR,intron-Distal5.0485814.07248K562UPF1
chr174576032745760380+3'-UTR,intron-Distal3.9659123.31012K562TARDBP
chr174575994345759965+3'-UTR3.8965810.53379K562TARDBP
chr174575976845759780+3'-UTR,intron-Proximal3.1157414.11981K562YBX3
chr174576192645761994+3'-UTR4.3026619.96936K562UPF1
chr174576055645760598+3'-UTR,intron-Distal3.1876412.13359K562ZC3H11A
chr174575997345759997+3'-UTR4.015827.40140K562YBX3
chr174576158245761644+3'-UTR,intron-Proximal3.506443.57974K562IGF2BP1
chr174576032545760380+3'-UTR,intron-Distal3.133757.29642K562IGF2BP1
chr174576053445760602+3'-UTR,intron-Distal3.8221813.99564K562U2AF1
chr174576004745760106+3'-UTR5.2731779.50888K562PABPC4
chr174576204645762112+3'-UTR4.442106.81682HepG2CSTF2
chr174575984145759871+3'-UTR4.024159.20314HepG2SUB1
chr174576020845760254+3'-UTR,intron-Proximal4.0204116.78492K562UPF1
chr174576018645760258+3'-UTR,intron-Distal,intron-Proximal6.9280851.59433HepG2SUB1
chr174573428145734345+3'-UTR,5'-UTR,CDS3.117573.40525HepG2AGGF1
chr174576156345761622+3'-UTR,intron-Distal,intron-Proximal3.5918913.03213K562FAM120A
chr174576064245760713+3'-UTR,intron-Distal3.1877328.97175K562FAM120A
chr174576155245761624+3'-UTR,intron-Distal,intron-Proximal3.044654.06711K562AKAP1
chr174576104145761095+3'-UTR,intron-Distal4.2207410.97985HepG2CSTF2
chr174576066445760719+3'-UTR,intron-Distal3.3373817.25375K562UPF1
chr174573425745734385+3'-UTR,5'-UTR,CDS3.3603514.50518HepG2G3BP1
chr174576017145760254+3'-UTR,intron-Proximal3.204765.75977HepG2UPF1
chr174576032045760327+3'-UTR,intron-Distal4.1558610.38178K562TARDBP
chr174576137645761428+3'-UTR,intron-Distal4.6686710.86155HepG2SUB1
chr174573422545734241+3'-UTR,5'-UTR,CDS,intron-Proximal3.2184010.21526HepG2BCLAF1
chr174576011645760154+3'-UTR3.3229810.62751K562UPF1
chr174573423745734343+3'-UTR,5'-UTR,CDS3.207786.70818K562NOLC1
chr174575988345759915+3'-UTR4.2116725.26597K562TARDBP
chr174576034245760374+3'-UTR,intron-Distal3.9245221.71377K562EIF4G2
chr174575988745759962+3'-UTR3.270157.35607HepG2UPF1
chr174575984245759883+3'-UTR4.9798519.69932K562TARDBP
chr174576063545760716+3'-UTR,intron-Distal3.2705814.58419K562PABPC4
chr174576021345760261+3'-UTR,intron-Distal,intron-Proximal3.8625416.39759K562TARDBP
chr174573422845734282+3'-UTR,5'-UTR,CDS3.761033.36793K562FXR1
chr174576194445761975+3'-UTR3.248578.45237K562FAM120A
chr174576032045760342+3'-UTR,intron-Distal3.7514120.73679K562EIF4G2
chr174576102045761041+3'-UTR,intron-Distal3.132056.61760HepG2CSTF2
chr174575977045759845+3'-UTR3.640765.59316K562SRSF1
chr174576071445760781+3'-UTR,intron-Distal3.0865412.31931K562FAM120A
chr174573422545734240+3'-UTR,5'-UTR,CDS,intron-Proximal3.153617.76680K562YBX3
chr174576182445761860+3'-UTR4.1031113.10983K562UPF1
chr174576186045761926+3'-UTR4.3468120.83878K562UPF1
chr174572777345727807+5'-UTR,CDS,intron-Distal3.339416.03511HepG2G3BP1
chr174572776145727797+5'-UTR,CDS,intron-Distal5.0612335.32240K562YBX3
chr174572780545727810+5'-UTR,CDS,intron-Distal4.572657.85254K562FMR1
chr174572767745727753+5'-UTR,CDS,intron-Distal,intron-Proximal4.444405.07796HepG2SF3B4
chr174573005145730114+5'-UTR,CDS,intron-Proximal3.427718.30660K562BUD13
chr174572753445727619+5'-UTR,CDS,intron-Distal,intron-Proximal3.101495.43939K562GEMIN5
chr174572751245727562+5'-UTR,intron-Distal,intron-Proximal3.904585.96194HepG2PCBP2
chr174573001645730103+5'-UTR,CDS,intron-Proximal3.418977.49660K562SF3B4
chr174572777745727805+5'-UTR,CDS,intron-Distal4.2279010.94818K562FMR1
chr174572732045727377+5'-UTR,intron-Distal,intron-Proximal3.065925.51422HepG2PCBP2
chr174572775145727753+5'-UTR,CDS,intron-Distal,intron-Proximal5.1280940.54024K562YBX3
chr174572779745727810+5'-UTR,CDS,intron-Distal5.348668.89821K562FXR2
chr174572731245727420+5'-UTR,intron-Distal,intron-Proximal3.7153014.02338K562PCBP1
chr174572780345727844+5'-UTR,CDS,intron-Distal,intron-Proximal3.395635.15019HepG2EFTUD2
chr174572770245727741+5'-UTR,intron-Distal,intron-Proximal3.045323.09962HepG2BUD13
chr174573022145730234+5'-UTR,CDS3.824265.52342HepG2PPIG
chr174572777345727824+5'-UTR,CDS,intron-Distal,intron-Proximal3.532506.66658HepG2SRSF1
chr174572775345727757+5'-UTR,CDS,intron-Distal4.8635428.14856K562YBX3
chr174572775045727829+5'-UTR,CDS,intron-Distal,intron-Proximal3.1205318.90466HepG2PPIG
chr174572732545727422+5'-UTR,intron-Distal,intron-Proximal3.729423.27226HepG2IGF2BP3
chr174573007645730132+5'-UTR,CDS3.286226.62827K562FXR2
chr174572753945727567+5'-UTR,intron-Distal,intron-Proximal3.289716.18332HepG2GRWD1
chr174572732645727446+5'-UTR,intron-Distal,intron-Proximal3.148036.43731K562IGF2BP2
chr174572779745727808+5'-UTR,CDS,intron-Distal3.675085.32768K562YBX3
chr174572779445727810+5'-UTR,CDS,intron-Distal3.263675.37330K562DDX3X
chr174573005945730076+5'-UTR,CDS,intron-Proximal3.646955.62598K562FXR2
chr174572773245727782+5'-UTR,CDS,intron-Distal,intron-Proximal3.053614.02686HepG2U2AF2
chr174572780845727854+5'-UTR,CDS,intron-Distal,intron-Proximal3.232324.71929HepG2PRPF8
chr174572756945727620+5'-UTR,CDS,intron-Distal3.7636910.83112K562FXR2
chr174573007845730108+5'-UTR,CDS3.861286.24124HepG2G3BP1
chr174572775045727805+5'-UTR,CDS,intron-Distal,intron-Proximal5.401607.65871K562METAP2
chr174572775045727773+5'-UTR,CDS,intron-Distal,intron-Proximal3.111394.79049HepG2SRSF1
chr174572767945727747+5'-UTR,intron-Distal,intron-Proximal4.2584310.67613HepG2EFTUD2
chr174573017545730221+5'-UTR,CDS3.225857.44928HepG2PPIG
chr174572775045727787+5'-UTR,CDS,intron-Distal,intron-Proximal3.9365012.73098K562FXR2
chr174573005945730081+5'-UTR,CDS,intron-Proximal4.285798.39949K562FMR1
chr174572772045727781+5'-UTR,CDS,intron-Distal,intron-Proximal3.7329412.48166HepG2PRPF8
chr174573848445738516+CDS,intron-Proximal4.138553.18004K562FXR1
chr174572762245727684+CDS,intron-Distal,intron-Proximal3.670719.58630HepG2PRPF8
chr174575038445750400+CDS3.766393.45590K562GRWD1
chr174575788545757904+CDS3.350084.69685K562FUS
chr174575090345750968+CDS,intron-Proximal4.057945.76569HepG2PRPF8
chr174574242145742454+CDS,intron-Distal,intron-Proximal3.5877912.82051HepG2PPIG
chr174574576245745806+CDS,intron-Proximal3.266446.29405HepG2PRPF8
chr174575092645750934+CDS,intron-Proximal3.594189.75075K562AQR
chr174574816145748197+CDS3.397235.59577K562SND1
chr174574042645740470+CDS,intron-Proximal5.181375.69951K562AQR
chr174575542045755445+CDS3.497664.45064HepG2GRWD1
chr174574572645745774+CDS5.0389716.73160K562LIN28B
chr174574252345742568+CDS,intron-Distal,intron-Proximal3.108504.73940K562SF3B4
chr174575438945754444+CDS3.752227.98704HepG2G3BP1
chr174574050645740541+CDS3.044228.30744HepG2BCLAF1
chr174574708945747149+CDS4.024588.39949K562FMR1
chr174575038445750409+CDS3.184347.54801HepG2GRWD1
chr174573587445735947+CDS3.192243.40171HepG2UCHL5
chr174575200645752024+CDS3.7083212.23319K562YBX3
chr174575550345755556+CDS,intron-Proximal3.2887611.99371HepG2BCLAF1
chr174575385045753891+CDS,intron-Proximal5.039724.68690HepG2PRPF8
chr174575541145755440+CDS,intron-Proximal3.604863.88337HepG2FXR2
chr174574152445741562+CDS,intron-Distal,intron-Proximal3.875424.55748K562ZNF800
chr174574716945747234+CDS4.9604413.96543K562FXR2
chr174575789245757984+CDS3.619677.55225HepG2FXR2
chr174575448645754536+CDS,intron-Proximal3.715486.32052K562AQR
chr174573850245738517+CDS4.627184.75028K562FXR2
chr174575038345750432+CDS,intron-Proximal3.557736.96362K562FXR2
chr174575438845754447+CDS4.124895.24156K562FXR1
chr174573597845736044+CDS,intron-Proximal3.433924.22460K562RBM15
chr174575038345750419+CDS,intron-Proximal3.583466.26235K562FMR1
chr174575743145757483+CDS3.753313.73851K562FXR1
chr174573441345734426+CDS3.269597.13168HepG2BCLAF1
chr174575567345755703+CDS,intron-Proximal3.662604.28265HepG2FXR2
chr174574806645748082+CDS,intron-Proximal3.838623.61330K562FXR1
chr174575208445752146+CDS3.371577.65308HepG2G3BP1
chr174573848645738541+CDS3.3565410.62277HepG2BCLAF1
chr174573596645735997+CDS3.640136.25351HepG2G3BP1
chr174575541145755439+CDS,intron-Proximal3.596354.56250HepG2SRSF7
chr174575799345758034+CDS3.158406.60114HepG2G3BP1
chr174573847045738497+CDS,intron-Proximal4.473245.46314K562U2AF2
chr174574157245741634+CDS,intron-Distal3.6483711.16701K562DDX24
chr174574717945747232+CDS3.327438.32357HepG2G3BP1
chr174575088845750903+CDS3.311446.00087K562YBX3
chr174574561345745657+CDS3.844437.23258K562RPS3
chr174575551945755556+CDS,intron-Proximal4.016419.88739K562FXR2
chr174574156245741610+CDS,intron-Distal3.372774.41873K562ZNF800
chr174574556445745642+CDS4.2587016.68973K562FXR2
chr174574153845741636+CDS,intron-Distal,intron-Proximal3.1731230.23674HepG2BCLAF1
chr174574156145741613+CDS,intron-Distal3.510275.14644K562NOLC1
chr174573846945738516+CDS,intron-Proximal3.357203.57123K562GPKOW
chr174574240345742458+CDS,intron-Distal,intron-Proximal3.6233814.39942HepG2BUD13
chr174572763445727647+CDS,intron-Distal3.353484.22242HepG2G3BP1
chr174574051145740604+CDS,intron-Proximal6.9746115.26202HepG2PRPF8
chr174575547645755556+CDS,intron-Proximal3.7177712.97200HepG2G3BP1
chr174574819445748242+CDS,intron-Proximal3.992118.27931K562AQR
chr174575378045753827+CDS4.2658710.40970K562LIN28B
chr174575051045750578+CDS,intron-Proximal4.1424315.77157HepG2PRPF8
chr174575541145755456+CDS,intron-Proximal3.028057.47562K562FXR2
chr174574040645740487+CDS,intron-Proximal3.356078.66679HepG2BUD13
chr174575445445754487+CDS3.654284.14015K562DDX24
chr174574813145748198+CDS3.177314.30277K562FXR1
chr174574722745747235+CDS3.987695.49678K562FMR1
chr174575205345752141+CDS3.670479.47436K562RPS3
chr174573595845736000+CDS3.012284.87903HepG2GRWD1
chr174572762645727651+CDS,intron-Distal,intron-Proximal3.028983.38491K562METAP2
chr174574246945742516+CDS,intron-Distal3.303166.40070HepG2G3BP1
chr174574040345740479+CDS,intron-Proximal3.700715.85504K562SF3B4
chr174575577745755842+CDS,intron-Proximal4.445209.80019K562AQR
chr174574252245742542+CDS,intron-Distal,intron-Proximal3.858798.13013K562AQR
chr174575210345752171+CDS,intron-Proximal3.356779.68110HepG2BUD13
chr174575377345753780+CDS,intron-Proximal4.466178.16865K562LIN28B
chr174574162045741635+CDS,intron-Distal3.179263.24717K562ZNF800
chr174574154745741608+CDS,intron-Distal3.571228.54752HepG2G3BP1
chr174574715945747221+CDS3.635317.61762K562FMR1
chr174575038345750419+CDS,intron-Proximal4.037906.74775HepG2G3BP1
chr174573850445738545+CDS,intron-Proximal3.2306210.72911HepG2U2AF2
chr174575575145755821+CDS,intron-Proximal4.7087114.63596HepG2PRPF8
chr174574557745745651+CDS3.256976.90893HepG2GRWD1
chr174574808245748131+CDS4.018194.53130K562FXR1
chr174575567545755681+CDS4.738384.59551K562FXR2
chr174574714845747216+CDS3.598425.34554K562FXR1
chr174574565245745683+CDS3.589036.81726HepG2GRWD1
chr174574162645741682+CDS,intron-Distal,intron-Proximal3.4396610.10185HepG2PRPF8
chr174575438745754448+CDS4.0297711.61235K562FMR1
chr174573853345738581+CDS,intron-Proximal3.226954.13013K562SF3B4
chr174574052645740614+CDS,intron-Proximal4.4752117.40230K562PRPF8
chr174575543945755457+CDS4.056565.21457HepG2SRSF7
chr174575569745755768+CDS3.499754.24516HepG2UCHL5
chr174575090545750927+CDS4.6619912.28420K562YBX3
chr174573594945736012+CDS4.0074828.22742HepG2BCLAF1
chr174573854245738551+CDS,intron-Proximal4.111284.88100K562AQR
chr174573848445738520+CDS,intron-Proximal4.0902113.22713K562LIN28B
chr174575446745754532+CDS,intron-Proximal4.9960113.14214HepG2PRPF8
chr174573852045738544+CDS3.920114.75351K562LIN28B
chr174575787645757993+CDS3.4219317.10299HepG2G3BP1
chr174574806745748105+CDS,intron-Proximal4.125129.73550K562FMR1
chr174574568345745711+CDS4.5606211.49169HepG2GRWD1
chr174575200345752042+CDS,intron-Proximal3.822064.17020K562FXR1
chr174574817545748199+CDS,intron-Proximal3.339415.03485HepG2G3BP1
chr174574711645747221+CDS3.6074712.40338K562RPS3
chr174574242145742448+CDS,intron-Distal,intron-Proximal3.928884.55748K562ZNF800
chr174573849645738534+CDS3.004553.47684HepG2GRWD1
chr174573847745738504+CDS,intron-Proximal3.6156516.07768HepG2U2AF2
chr174575787345757885+CDS,intron-Proximal3.028323.60351K562FUS
chr174574566445745776+CDS3.3246919.71910HepG2G3BP1
chr174573589245735958+CDS3.2958412.15089HepG2GRWD1
chr174575086145750927+CDS3.107854.10434K562FXR1
chr174575568145755781+CDS,intron-Proximal3.1779412.62988K562DDX24
chr174574044045740481+CDS,intron-Proximal4.204158.46556K562BUD13
chr174575038545750414+CDS4.636843.39858K562IGF2BP2
chr174573587445735949+CDS3.4898823.88532HepG2BCLAF1
chr174573846945738541+CDS,intron-Proximal3.5031610.89935K562BUD13
chr174575541045755457+CDS,intron-Proximal3.075517.16368HepG2PPIG
chr174575212145752158+CDS,intron-Proximal3.883976.55928HepG2PRPF8
chr174572761545727650+CDS,intron-Distal5.0288940.25127K562YBX3
chr174575438845754444+CDS4.0297911.37034K562FXR2
chr174573842545738533+CDS,intron-Proximal4.8046624.26993K562SF3B4
chr174575550845755553+CDS3.290514.29277HepG2GRWD1
chr174574571245745775+CDS3.2969319.17701HepG2BCLAF1
chr174574571145745772+CDS3.6816311.62654HepG2GRWD1
chr174575200345752006+CDS,intron-Proximal4.4062910.52552K562YBX3
chr174575569045755741+CDS3.525269.82789HepG2G3BP1
chr174574160845741635+CDS,intron-Distal3.186617.39452HepG2G3BP1
chr174575085945750891+CDS3.658405.22975HepG2G3BP1
chr174574042145740484+CDS,intron-Proximal3.699957.75156HepG2AQR
chr174575575345755793+CDS,intron-Proximal3.056355.03020HepG2SRSF1
chr174574245545742519+CDS,intron-Distal3.487317.83494K562RPS3
chr174573758445737646+intron-Distal3.351063.37783HepG2TIAL1
chr174573613445736238+intron-Distal3.8691139.76520K562EFTUD2
chr174572842545728475+intron-Distal4.164797.75444K562PRPF8
chr174574254245742601+intron-Distal,intron-Proximal5.2052414.28850K562AQR
chr174573635745736404+intron-Distal3.657433.50879HepG2EFTUD2
chr174572823145728307+intron-Distal3.060107.77500HepG2PCBP2
chr174573610445736134+intron-Distal,intron-Proximal4.4197122.10004K562EFTUD2
chr174575597745756005+intron-Distal4.201734.45335HepG2HNRNPC
chr174574165645741685+intron-Distal,intron-Proximal5.8650911.56697K562AQR
chr174573628045736340+intron-Distal3.5954611.40043K562PRPF8
chr174575600545756033+intron-Distal3.913983.03357HepG2HNRNPC
chr174572905945729107+intron-Distal4.071073.16986HepG2QKI
chr174572784345727892+intron-Distal,intron-Proximal3.743833.06084HepG2HNRNPK
chr174573870145738766+intron-Distal5.206454.17759HepG2QKI
chr174572817645728255+intron-Distal3.362066.81166HepG2XPO5
chr174572796045728026+intron-Distal5.429749.83211HepG2PCBP2
chr174575152345751628+intron-Distal4.170023.37208HepG2ILF3
chr174574061645740675+intron-Distal,intron-Proximal3.985255.85201K562PRPF8
chr174572794445728024+intron-Distal4.072623.83943K562HNRNPK
chr174573624845736280+intron-Distal5.008395.50285K562PRPF8
chr174572797845728047+intron-Distal4.681739.18671HepG2XRN2
chr174572793545727977+intron-Distal4.248563.57018HepG2HNRNPK
chr174572794945728006+intron-Distal3.724486.22853HepG2DDX59
chr174574143345741523+intron-Distal,intron-Proximal3.665535.26543HepG2RBFOX2
chr174573627745736337+intron-Distal3.454198.87315K562EFTUD2
chr174575176045751897+intron-Distal4.070527.53395K562KHSRP
chr174572784445727909+intron-Distal,intron-Proximal4.1260710.41279HepG2RBM22
chr174573610445736195+intron-Distal,intron-Proximal3.147406.49528HepG2EFTUD2
chr174573614645736248+intron-Distal3.4883716.89347K562PRPF8
chr174575119945751259+intron-Distal3.545224.97292HepG2ILF3
chr174574057145740625+intron-Proximal4.096234.95583K562RBM22
chr174573856945738586+intron-Proximal5.955119.41643K562AQR
chr174573846845738477+intron-Proximal3.7971011.60095HepG2U2AF2
chr174575215845752189+intron-Proximal6.2106810.09256HepG2PRPF8
chr174575579345755828+intron-Proximal6.6599321.49098K562PRPF8
chr174575093445750973+intron-Proximal4.5436612.86643K562AQR
chr174575371745753770+intron-Proximal4.378834.59919HepG2AQR
chr174575584345755866+intron-Proximal3.734653.54718K562PRPF8
chr174573855145738569+intron-Proximal4.738046.48405K562AQR
chr174575194745752002+intron-Proximal6.6379516.14972K562SF3B4
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for KPNB1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for KPNB1 is not available on ENCORE database.

  • 118 RBPs can affect the levels of KPNB1.  








The Knockdown/knockout RNA-Seq assay for KPNB1 is not available on ENCORE database.





118 RBPs can affect the gene expression of KPNB1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
KPNB1ENSG00000108424.53523.365908020.38230-1.1867023.2393020.61470HepG2AKAP8
KPNB1ENSG00000108424.59316.425607725.437300.270101.991001.32040HepG2ASCC1
KPNB1ENSG00000108424.510769.2245013223.91010-0.296206.294205.32570HepG2AUH
KPNB1ENSG00000108424.56475.114408539.16270-0.399203.042802.05700HepG2BCCIP
KPNB1ENSG00000108424.55030.143507420.03050-0.560806.072004.79910HepG2BCLAF1
KPNB1ENSG00000108424.56762.2773011105.09970-0.7156014.0426012.84170HepG2BOP1
KPNB1ENSG00000108424.57566.746309682.49730-0.355705.558204.51270HepG2CALR
KPNB1ENSG00000108424.56708.309008327.99790-0.312008.816407.75920HepG2CKAP4
KPNB1ENSG00000108424.55325.202207258.93180-0.446902.506801.78140HepG2CNOT7
KPNB1ENSG00000108424.57357.5810010195.04220-0.470605.971504.99540HepG2CPSF6
KPNB1ENSG00000108424.58557.3562010704.07500-0.322905.941105.06610HepG2CELF1
KPNB1ENSG00000108424.58188.3205011508.80680-0.4911021.6189019.90910HepG2DAZAP1
KPNB1ENSG00000108424.55991.101407703.76400-0.362709.988208.59410HepG2DDX19B
KPNB1ENSG00000108424.54825.002507419.53130-0.6208010.985209.73760HepG2DDX21
KPNB1ENSG00000108424.55349.544707172.54340-0.423105.387504.04840HepG2DHX30
KPNB1ENSG00000108424.56015.101107969.19630-0.4058010.405409.26200HepG2DKC1
KPNB1ENSG00000108424.56243.386107436.53360-0.252303.608402.81180HepG2DNAJC21
KPNB1ENSG00000108424.55198.323007370.91880-0.5038020.9313019.29240HepG2DNAJC2
KPNB1ENSG00000108424.56028.273407385.85190-0.293002.219901.68290HepG2EIF2S1
KPNB1ENSG00000108424.55895.047008162.09580-0.469404.164403.38460HepG2EIF4A3
KPNB1ENSG00000108424.510229.966207947.210600.364202.225701.60520HepG2EIF4B
KPNB1ENSG00000108424.54408.190705532.84020-0.327804.300102.81570HepG2FAM120A
KPNB1ENSG00000108424.55453.721504575.925000.253102.315601.59230HepG2FUBP3
KPNB1ENSG00000108424.53620.502505511.77230-0.606308.412006.89250HepG2GEMIN5
KPNB1ENSG00000108424.56335.9807011556.75320-0.8671014.2322012.88910HepG2GPKOW
KPNB1ENSG00000108424.54050.646107507.77820-0.8902022.4274020.89300HepG2HNRNPA1
KPNB1ENSG00000108424.58938.7061010577.26170-0.242803.858202.78190HepG2HNRNPA2B1
KPNB1ENSG00000108424.56204.153808351.03250-0.428705.732004.76140HepG2HNRNPC
KPNB1ENSG00000108424.58039.1349011440.35570-0.5090016.1687014.62460HepG2HNRNPF
KPNB1ENSG00000108424.59560.879307736.237900.305402.870602.15840HepG2HNRNPK
KPNB1ENSG00000108424.57321.9564010483.42930-0.5178025.0072023.19550HepG2HNRNPL
KPNB1ENSG00000108424.57534.3910011028.83350-0.549707.371506.40160HepG2HNRNPLL
KPNB1ENSG00000108424.56006.550108295.81920-0.4658014.0497012.77370HepG2HNRNPU
KPNB1ENSG00000108424.57552.3183011265.48250-0.5769012.5465011.12100HepG2IGF2BP1
KPNB1ENSG00000108424.55114.550107765.34270-0.602407.846306.76960HepG2IGF2BP2
KPNB1ENSG00000108424.56282.394008473.90180-0.4317017.7492016.07690HepG2ILF2
KPNB1ENSG00000108424.56761.619307614.41680-0.171403.077002.00350HepG2KIF1C
KPNB1ENSG00000108424.56215.852607800.51730-0.327603.254301.93820HepG2LIN28B
KPNB1ENSG00000108424.56490.273708284.55120-0.352102.672302.05170HepG2MATR3
KPNB1ENSG00000108424.57228.887309109.11020-0.333503.788602.84500HepG2MSI2
KPNB1ENSG00000108424.56830.3701011248.24210-0.719706.559305.03070HepG2MTPAP
KPNB1ENSG00000108424.59699.7411011412.14670-0.234602.730501.97180HepG2NOL12
KPNB1ENSG00000108424.55871.179307551.42020-0.363103.057102.30080HepG2PABPC4
KPNB1ENSG00000108424.56232.206307736.57420-0.312006.477705.60930HepG2PCBP1
KPNB1ENSG00000108424.55159.977808634.48090-0.742706.641505.08840HepG2PCBP2
KPNB1ENSG00000108424.55821.648807399.20490-0.345905.997004.94490HepG2PPIL4
KPNB1ENSG00000108424.54199.870206477.07310-0.625008.074606.77900HepG2PRPF8
KPNB1ENSG00000108424.56473.472207872.34970-0.282305.479904.76480HepG2PTBP1
KPNB1ENSG00000108424.57523.8368010894.08710-0.534008.994108.00260HepG2PUF60
KPNB1ENSG00000108424.54539.524508484.23390-0.9022055.1997053.17600HepG2PUS1
KPNB1ENSG00000108424.59965.000608525.744000.224902.754202.13050HepG2QKI
KPNB1ENSG00000108424.512907.657508332.763100.631304.100603.25110HepG2RAVER1
KPNB1ENSG00000108424.510252.0996011847.56010-0.208702.123901.35950HepG2RBM15
KPNB1ENSG00000108424.59321.8297012690.20760-0.4450010.720809.84760HepG2RBM22
KPNB1ENSG00000108424.59321.621608159.909200.191902.998802.36070HepG2RECQL
KPNB1ENSG00000108424.57640.3829012324.09450-0.6898013.7352012.43020HepG2RPLP0
KPNB1ENSG00000108424.54890.980308184.78610-0.742806.433705.03710HepG2RPS10
KPNB1ENSG00000108424.54453.461406023.65780-0.435706.287405.40190HepG2RPS19
KPNB1ENSG00000108424.56530.255408261.84260-0.339303.232802.36740HepG2RPS2
KPNB1ENSG00000108424.54448.535907289.71360-0.712507.048705.78300HepG2RPS3A
KPNB1ENSG00000108424.54242.209206407.21320-0.594906.503705.35490HepG2RRP9
KPNB1ENSG00000108424.55520.538107387.78360-0.4203013.5848012.31850HepG2SAFB2
KPNB1ENSG00000108424.57357.7646010916.29630-0.569109.057007.85110HepG2SF3B1
KPNB1ENSG00000108424.58412.5466010446.19770-0.312409.038607.88510HepG2SLBP
KPNB1ENSG00000108424.56592.447808494.71300-0.365802.214501.36730HepG2SMNDC1
KPNB1ENSG00000108424.59033.7700014333.01620-0.6659035.7136034.44670HepG2SRFBP1
KPNB1ENSG00000108424.512563.778808554.877900.5544023.5054022.42110HepG2SRSF1
KPNB1ENSG00000108424.57349.9220011239.77810-0.6128023.5030021.85530HepG2SRSF7
KPNB1ENSG00000108424.510329.1300012444.26580-0.268805.850105.15740HepG2SSB
KPNB1ENSG00000108424.55091.7677010750.01990-1.0781028.6915026.82620HepG2TARDBP
KPNB1ENSG00000108424.54365.159905602.10160-0.359902.976701.94460HepG2TFIP11
KPNB1ENSG00000108424.54349.260208060.87320-0.8902028.8786027.57920HepG2TIAL1
KPNB1ENSG00000108424.54304.433908133.00160-0.9180049.1757047.18160HepG2TRIM56
KPNB1ENSG00000108424.52814.103304937.37220-0.8111012.8623011.25360HepG2UCHL5
KPNB1ENSG00000108424.56206.552008946.11190-0.5275019.5838018.05390HepG2UPF1
KPNB1ENSG00000108424.57499.878709195.27460-0.294005.225503.82780HepG2UTP18
KPNB1ENSG00000108424.512123.312908637.103800.4891017.7672016.44690HepG2UTP3
KPNB1ENSG00000108424.54376.318006529.45030-0.577204.585103.15850HepG2XPO5
KPNB1ENSG00000108424.56453.177608227.44530-0.350402.968802.21730HepG2XRN2
KPNB1ENSG00000108424.57822.854809235.01160-0.239405.564704.66410HepG2ZC3H8
KPNB1ENSG00000108424.58290.520509838.99600-0.247006.530905.78410HepG2ZNF622
KPNB1ENSG00000108424.520795.3232018055.024300.203803.725003.08460K562AGGF1
KPNB1ENSG00000108424.59584.9772019839.82960-1.0496029.8126026.31760K562AKAP8
KPNB1ENSG00000108424.510380.0651021773.45160-1.0688030.4812028.72970K562AQR
KPNB1ENSG00000108424.511568.7885013742.09460-0.248404.021302.38560K562BCCIP
KPNB1ENSG00000108424.511431.8349013280.17670-0.216204.078802.89520K562BCLAF1
KPNB1ENSG00000108424.59868.5182014119.66340-0.516806.919905.52150K562BOP1
KPNB1ENSG00000108424.56263.897507634.17790-0.285402.396801.43030K562CCAR1
KPNB1ENSG00000108424.517535.7085023871.25800-0.445002.340401.37870K562CNOT7
KPNB1ENSG00000108424.510453.0489015013.40290-0.5223010.174508.65860K562CPSF6
KPNB1ENSG00000108424.58113.3220010074.99400-0.312405.562903.98290K562CSTF2
KPNB1ENSG00000108424.514040.0545016356.31420-0.220303.541802.16930K562DDX21
KPNB1ENSG00000108424.59472.7585011735.29840-0.309003.540702.34190K562DDX3X
KPNB1ENSG00000108424.527614.0722022729.642400.280705.821604.92750K562DDX47
KPNB1ENSG00000108424.59640.5346012175.17750-0.336803.090302.12280K562EFTUD2
KPNB1ENSG00000108424.513301.8813017513.21050-0.396809.011407.82650K562EIF2S2
KPNB1ENSG00000108424.513802.8624010708.945000.366104.513003.50700K562EIF3G
KPNB1ENSG00000108424.57681.4926012260.75670-0.6746012.5981010.80490K562EIF4A3
KPNB1ENSG00000108424.514889.1677018565.99240-0.318403.323202.38810K562FIP1L1
KPNB1ENSG00000108424.511770.6055015275.49170-0.376004.157903.10710K562FMR1
KPNB1ENSG00000108424.59183.0428012947.23140-0.495605.728504.36170K562FTO
KPNB1ENSG00000108424.58937.2109012206.33210-0.449704.608402.74190K562GEMIN5
KPNB1ENSG00000108424.510058.5736014334.22470-0.511008.229006.85640K562GPKOW
KPNB1ENSG00000108424.514684.2656023338.18050-0.6684015.4477013.62520K562GRSF1
KPNB1ENSG00000108424.58357.7867012586.29710-0.5907011.9054010.74000K562HNRNPC
KPNB1ENSG00000108424.519618.7165015242.495000.364003.447702.05100K562HNRNPK
KPNB1ENSG00000108424.521363.2320025171.62010-0.236702.011101.32770K562HSPD1
KPNB1ENSG00000108424.59373.2468012239.32660-0.384902.683601.76750K562KRR1
KPNB1ENSG00000108424.511795.9079016039.35010-0.443306.379605.07920K562MAGOH
KPNB1ENSG00000108424.513354.5201016006.72500-0.261402.809901.88000K562MATR3
KPNB1ENSG00000108424.510583.6067013991.75230-0.402705.631704.35450K562METAP2
KPNB1ENSG00000108424.522152.7517029559.68360-0.416104.791003.30310K562MSI2
KPNB1ENSG00000108424.513806.7973017203.71750-0.317308.227506.90300K562MTPAP
KPNB1ENSG00000108424.516436.6562019114.86870-0.217807.615306.46110K562NSUN2
KPNB1ENSG00000108424.58891.9194016527.56310-0.894305.768604.18540K562PABPN1
KPNB1ENSG00000108424.512644.5154015678.68570-0.310303.954702.32650K562PCBP1
KPNB1ENSG00000108424.510505.5413017899.32230-0.7688012.2948010.54910K562PCBP3
KPNB1ENSG00000108424.523610.1542028494.81950-0.271302.796201.34800K562PNPT1
KPNB1ENSG00000108424.57943.0797013729.57130-0.7895022.9525020.80880K562POLR2G
KPNB1ENSG00000108424.516770.7310021075.99560-0.329703.299302.38950K562PPIG
KPNB1ENSG00000108424.59128.5660011284.78590-0.305903.156102.18110K562PSIP1
KPNB1ENSG00000108424.510752.2155015583.27550-0.5354010.200408.98120K562PTBP1
KPNB1ENSG00000108424.523350.3992031533.91240-0.4335010.368008.48170K562PUM2
KPNB1ENSG00000108424.513316.2700018631.48920-0.484606.183505.41100K562PUS1
KPNB1ENSG00000108424.520378.9150018153.705100.166701.886301.37980K562RBM15
KPNB1ENSG00000108424.511381.3629014942.19080-0.392704.597603.48150K562RBM22
KPNB1ENSG00000108424.58311.4406010295.19180-0.308803.946502.76070K562RCC2
KPNB1ENSG00000108424.512237.0777015724.33800-0.361703.507602.25590K562NELFE
KPNB1ENSG00000108424.510953.9353013325.34050-0.282702.416901.48850K562RPS3
KPNB1ENSG00000108424.516726.1557019324.02180-0.208304.901803.70130K562SRPK2
KPNB1ENSG00000108424.59946.9066012864.43170-0.371105.284603.74520K562SRSF4
KPNB1ENSG00000108424.512320.1355014596.84250-0.244603.931902.51750K562SRSF7
KPNB1ENSG00000108424.58438.5921011472.49010-0.443104.140802.87710K562SUPV3L1
KPNB1ENSG00000108424.515808.9664013770.868000.199002.071901.36090K562SYNCRIP
KPNB1ENSG00000108424.58765.5120015461.05100-0.8187015.7707013.81410K562TARDBP
KPNB1ENSG00000108424.512699.0133014913.96570-0.231902.438301.67530K562TIA1
KPNB1ENSG00000108424.57885.7126010854.16310-0.460904.946803.66180K562TIAL1
KPNB1ENSG00000108424.58166.1350011530.34880-0.497707.480705.75150K562TRIM56
KPNB1ENSG00000108424.516326.0365012322.223500.405803.522602.25470K562U2AF1
KPNB1ENSG00000108424.515335.4771012726.463900.268903.290502.41660K562U2AF2
KPNB1ENSG00000108424.58390.7699012141.60030-0.533106.771705.09900K562UCHL5
KPNB1ENSG00000108424.516187.1565020267.90110-0.324308.793807.60100K562UPF1
KPNB1ENSG00000108424.516002.9078019725.84530-0.301802.436901.31660K562UTP3
KPNB1ENSG00000108424.514094.8146017342.60200-0.299203.571702.57950K562WDR3
KPNB1ENSG00000108424.512909.7670018034.29960-0.4823019.6087017.66190K562WDR43
KPNB1ENSG00000108424.510016.0377012362.56870-0.303702.455101.33790K562XRN2
KPNB1ENSG00000108424.519722.8035024527.75310-0.314603.364902.40020K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for KPNB1 is not available on ENCORE database.





7 RBPs can affect the splicing of KPNB1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEKPNB1ENSG00000108424.5chr17+457508554575092745750383457505314575200345752148-0.072000.000000.00000excludedK562SF3B4
SEKPNB1ENSG00000108424.5chr17+457508294575092745750383457505314575200345752121-0.088000.000190.00504excludedHepG2U2AF1
SEKPNB1ENSG00000108424.5chr17+457508294575092745750282457505314575200345752148-0.054000.000000.00002excludedK562AQR
SEKPNB1ENSG00000108424.5chr17+457404254574054445738484457385444574152445741635-0.058000.000000.00000excludedK562PUS1
SEKPNB1ENSG00000108424.5chr17+457508114575092745750383457505314575200345752121-0.077000.000010.00080excludedHepG2SF3A3
MXEKPNB1ENSG00000108424.5chr17+45740454457405444574242245742524457384844573854445745551457457760.068000.001530.024411includedK562DROSHA
MXEKPNB1ENSG00000108424.5chr17+45740454457405444574242245742524457384844573854445745551457457760.068000.001770.034031includedK562HNRNPUL1
MXEKPNB1ENSG00000108424.5chr17+45740454457405444574152445741635457384844573854445742422457425240.117000.000040.002161includedK562HNRNPUL1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for KPNB1 is not avaliable on ENCORE database.