KARS

General Information

Gene Name       : KARS
Gene ID             : ENSG00000065427.14
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: KARS)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878KARSENSG00000065427.14189.72190.35190.03ENCSR000AEF
HepG2KARSENSG00000065427.14181.08231.48206.28ENCSR985KAT
K562KARSENSG00000065427.14253.90259.45256.68ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  
  GeneName    Antibody_DCC_ID    Product_ID    Lot_ID    Phosphate    HepG2 Primary Validation    K562 Primary Validation    HepG2 Secondary Validation    K562 Secondary Validation  
KARS9990S1Submitted, ENCORE2BGHcLV43-25, Submitted, ENCORE2BGKcLV42-45, Submitted, ENCORE2


  KD RNA-Seq  
  GeneName    Cell_Line    Method    Exp_ID    Control_ID    Sample_reps    Control_reps    KD%    Status    Project    Note  
KARSK562CRISPRKARS-BGKcLV42-45,KARS-BGKcLV42-46NT-BGKcLV42-1,NT-BGKcLV42-296.4,98.1SequencedENCORE2
KARSHepG2CRISPRKARS-BGHcLV43-25,KARS-BGHcLV43-26NT-BGHcLV43-1,NT-BGHcLV43-277.9,87.0SequencedENCORE2


  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela
KARSProduct_ID: 9990S
Lot_ID: 1
Source: Cell Signaling Technology
Target Name: KARS-human		 KARS-HEPG2-CRISPR-9990S.png<br>Caption: Western blot following CRISPR against KARS in HepG2 whole cell lysate using KARS specific antibody. Lane 1 is a ladder, lane 2 is HepG2 non-targeting control knockdown, lane 3 and 4 are two different CRISPR against KARS. KARS protein appears as the green arrow, Beta-actin serves as a control and appears in red arrow.
 CST_9990S_1_KARS.png<br>Caption: IP-WB analysis of 9990S whole cell lysate using the KARS specific antibody, 9990S. Lanes 1 and 2 are 2.5% of five million whole cell lysate input and 50% of IP enrichment, respectively, using a normal IgG antibody. Lane 3 is 50% of IP enrichment from five million whole cell lysate using the KARS-specific antibody, 9990S. The same antibody was used to detect protein levels via Western blot. This antibody passes preliminary validation and will be further pursued for secondary validation. *NOTE* Protein sizes are taken from Genecards.org and are only estimates based on sequence. Actual protein size may differ based on protein characteristics and electrophoresis method used.
 KARS-K562-CRISPR-9990S.png<br>Caption: Western blot following CRISPR against KARS in K562 whole cell lysate using KARS specific antibody. Lane 1 is a ladder, lane 2 is K562 non-targeting control knockdown, lane 3 and 4 are two different CRISPR against KARS. KARS protein appears as the green arrow, Beta-actin serves as a control and appears in red arrow.








RNA Targets

  • eCLIP assay for KARS is not avaliable on ENCORE database.



Proteins bound to RNA
  • KARS RNA is bound by 19 proteins.  







eCLIP assay for KARS is not avaliable on ENCORE database.





19 proteins are bound to KARS RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr167567422575674246-3'-UTR,CDS,intron-Distal3.876433.39506K562IGF2BP2
chr167566242375662485-3'-UTR,CDS,intron-Distal,intron-Proximal3.323763.13980HepG2PRPF8
chr167566246675662481-3'-UTR,CDS,intron-Distal,intron-Proximal4.7966121.74379K562YBX3
chr167566166275661713-3'-UTR,intron-Distal,intron-Proximal3.644814.71673K562PABPC4
chr167566331275663361-3'-UTR,CDS,intron-Distal,intron-Proximal4.579674.88516K562METAP2
chr167566186275661871-3'-UTR,CDS,intron-Distal3.099087.19068K562YBX3
chr167566250375662556-3'-UTR,CDS,intron-Distal3.276813.71087K562METAP2
chr167566171375661816-3'-UTR,CDS,intron-Distal,intron-Proximal4.5119915.86474HepG2SUB1
chr167567546175675482-3'-UTR,CDS,intron-Distal,intron-Proximal3.872825.35703HepG2BCLAF1
chr167567415675674220-3'-UTR,CDS,intron-Distal4.996505.86239HepG2IGF2BP1
chr167566574475665748-3'-UTR,CDS,intron-Distal3.638085.32768K562YBX3
chr167567414775674247-3'-UTR,CDS,intron-Distal3.4542414.81296K562IGF2BP1
chr167566545075665454-3'-UTR,CDS,intron-Distal3.6957342.18918K562YBX3
chr167567558675675621-3'-UTR,CDS,intron-Distal,intron-Proximal3.645725.62957HepG2BUD13
chr167566501775665070-3'-UTR,CDS,intron-Distal,intron-Proximal3.932397.26133HepG2PRPF8
chr167567416675674240-3'-UTR,CDS,intron-Distal3.269606.60114HepG2G3BP1
chr167566246575662503-3'-UTR,CDS,intron-Distal,intron-Proximal3.098745.31732K562METAP2
chr167566177375661786-3'-UTR,intron-Distal3.453853.18912K562PABPC4
chr167566249775662509-3'-UTR,CDS,intron-Distal3.229667.38271K562YBX3
chr167566811175668172-3'-UTR,CDS,intron-Distal,intron-Proximal3.437866.49751K562IGF2BP2
chr167566541775665422-3'-UTR,CDS,intron-Distal3.7965652.39236K562YBX3
chr167566168375661753-3'-UTR,intron-Distal,intron-Proximal4.068935.75613K562ZNF800
chr167566176275661773-3'-UTR,intron-Distal4.431159.90371K562PABPC4
chr167567548375675543-3'-UTR,CDS,intron-Distal,intron-Proximal4.015504.65365HepG2GRWD1
chr167566561475665686-3'-UTR,CDS,intron-Distal,intron-Proximal3.518283.91115K562LIN28B
chr167566166475661755-3'-UTR,intron-Distal,intron-Proximal3.839494.05694K562IGF2BP1
chr167566179775661831-3'-UTR,CDS,intron-Distal3.672168.21916K562YBX3
chr167566166375661719-3'-UTR,intron-Distal,intron-Proximal3.312943.19560HepG2LARP4
chr167567420975674220-3'-UTR,CDS,intron-Distal3.0395711.46763K562YBX3
chr167566992075669946-3'-UTR,CDS,intron-Distal3.7297910.67597K562YBX3
chr167566957775669595-3'-UTR,CDS,intron-Distal,intron-Proximal3.280963.24162HepG2G3BP1
chr167566994675669961-3'-UTR,CDS,intron-Distal3.796518.62113K562YBX3
chr167566553975665601-3'-UTR,CDS,intron-Distal,intron-Proximal4.649414.45914HepG2PRPF8
chr167566991675669963-3'-UTR,CDS,intron-Distal4.7413011.09109HepG2BCLAF1
chr167566171375661762-3'-UTR,intron-Distal,intron-Proximal4.4726514.79781K562PABPC4
chr167566506575665105-3'-UTR,CDS,intron-Distal,intron-Proximal3.573445.49938HepG2G3BP1
chr167566166075661713-3'-UTR,intron-Distal,intron-Proximal5.5001516.75154HepG2SUB1
chr167566167475661723-3'-UTR,intron-Distal,intron-Proximal3.031483.00929K562LIN28B
chr167566187175661885-3'-UTR,CDS,intron-Distal3.8201012.10232K562YBX3
chr167567036275670411-3'-UTR,CDS,intron-Distal5.012568.37059HepG2G3BP1
chr167567555075675605-3'-UTR,CDS,intron-Distal,intron-Proximal3.423533.36903K562MTPAP
chr167566174275661776-3'-UTR,intron-Distal,intron-Proximal3.082088.52352K562YBX3
chr167566541375665417-3'-UTR,CDS,intron-Distal3.1805616.14611K562YBX3
chr167566248175662497-3'-UTR,CDS,intron-Distal4.7880722.63103K562YBX3
chr167566983075669921-3'-UTR,CDS,intron-Distal3.4440210.16304K562LIN28B
chr167567032975670384-3'-UTR,CDS,intron-Distal,intron-Proximal5.218904.02817HepG2PRPF8
chr167567546275675491-3'-UTR,CDS,intron-Distal3.988917.10432HepG2G3BP1
chr167566814075668190-3'-UTR,CDS,intron-Distal3.865928.77191HepG2G3BP1
chr167567417075674184-3'-UTR,CDS,intron-Distal3.3045513.37910K562YBX3
chr167566188575661891-3'-UTR,CDS,intron-Distal3.9865715.09148K562YBX3
chr167566542275665450-3'-UTR,CDS,intron-Distal3.9041158.46905K562YBX3
chr167566181975661888-3'-UTR,CDS,intron-Distal3.911707.11962HepG2G3BP1
chr167566991975669960-3'-UTR,CDS,intron-Distal3.148423.09251K562METAP2
chr167567411975674133-3'-UTR,CDS,intron-Distal3.5818813.12695K562YBX3
chr167566813975668191-3'-UTR,CDS,intron-Distal,intron-Proximal3.088323.66602K562GRWD1
chr167567554775675617-3'-UTR,CDS,intron-Distal,intron-Proximal3.363159.46864K562UCHL5
chr167566572875665752-3'-UTR,CDS,intron-Distal4.113713.02572K562SND1
chr167566998575669991-3'-UTR,CDS,intron-Distal,intron-Proximal3.310053.28366HepG2BCLAF1
chr167566328775663315-3'-UTR,CDS,intron-Distal,intron-Proximal4.385417.53589K562AQR
chr167568147575681481-5'-UTR,CDS,intron-Distal3.971833.01428K562UCHL5
chr167568142275681476-5'-UTR,intron-Distal3.153905.62208HepG2PRPF8
chr167568147275681557-5'-UTR,CDS,intron-Distal,intron-Proximal4.0063619.21794K562DDX3X
chr167566326975663287-intron-Distal,intron-Proximal4.167365.26367K562AQR
chr167566526675665307-intron-Distal,intron-Proximal4.243033.86479HepG2PRPF8
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for KARS is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for KARS is not available on ENCORE database.

  • 122 RBPs can affect the levels of KARS.  








The Knockdown/knockout RNA-Seq assay for KARS is not available on ENCORE database.





122 RBPs can affect the gene expression of KARS :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
KARSENSG00000065427.102304.585003160.74170-0.455803.875302.64710HepG2AKAP8
KARSENSG00000065427.103024.417503667.09990-0.278004.319003.37580HepG2AKAP8L
KARSENSG00000065427.103591.536804672.00120-0.379403.317902.45740HepG2ASCC1
KARSENSG00000065427.104036.198605953.49970-0.5607016.9393015.50400HepG2AUH
KARSENSG00000065427.102114.744103245.75690-0.618106.529205.21200HepG2BCLAF1
KARSENSG00000065427.102339.200903365.65470-0.524908.029606.03980HepG2BUD13
KARSENSG00000065427.103674.461505262.20710-0.518104.199802.98510HepG2CCAR1
KARSENSG00000065427.103643.209604438.73340-0.284902.113001.43160HepG2CIRBP
KARSENSG00000065427.102260.575603220.03280-0.510403.001402.20090HepG2CNOT7
KARSENSG00000065427.101546.158802886.70430-0.9007016.4727014.96150HepG2CPSF6
KARSENSG00000065427.101794.653102307.39950-0.362603.067301.93860HepG2CSTF2
KARSENSG00000065427.104486.548705598.02010-0.319308.071506.90550HepG2DAZAP1
KARSENSG00000065427.102647.114503403.76250-0.362703.850403.06320HepG2DDX21
KARSENSG00000065427.104447.314605408.88300-0.282401.991201.45210HepG2DDX3X
KARSENSG00000065427.102981.018403834.75810-0.363303.361102.25430HepG2DDX5
KARSENSG00000065427.102651.202104646.50980-0.8095010.595309.47320HepG2DDX6
KARSENSG00000065427.102881.271103567.29320-0.308102.758401.77460HepG2DHX30
KARSENSG00000065427.102546.151303492.22570-0.4558010.239409.10240HepG2DKC1
KARSENSG00000065427.102567.307803698.65560-0.5267011.5573010.20180HepG2DNAJC21
KARSENSG00000065427.102754.299803665.74990-0.4124011.6075010.37190HepG2DNAJC2
KARSENSG00000065427.101550.748204466.63650-1.5262039.5680037.51320HepG2EIF2S1
KARSENSG00000065427.101961.887604936.07800-1.3311026.5989024.66340HepG2EIF4A3
KARSENSG00000065427.106347.781005523.029000.200702.916302.06080HepG2EIF4G1
KARSENSG00000065427.103403.812205290.66550-0.636309.684208.20030HepG2EIF4G2
KARSENSG00000065427.103212.192403891.56600-0.276802.448401.41920HepG2ESF1
KARSENSG00000065427.103788.218406835.25440-0.8515039.8391038.05740HepG2ETF1
KARSENSG00000065427.102054.299502450.52930-0.254402.410201.32220HepG2FAM120A
KARSENSG00000065427.101906.809702891.68810-0.600802.308701.38760HepG2FTO
KARSENSG00000065427.104130.235904980.53900-0.270101.947401.36320HepG2FXR1
KARSENSG00000065427.102022.548304620.05230-1.1917023.2247021.38950HepG2G3BP1
KARSENSG00000065427.102360.247003293.15190-0.480504.416703.12140HepG2GNB2L1
KARSENSG00000065427.102221.174503272.25690-0.559005.715604.81840HepG2GPKOW
KARSENSG00000065427.102786.114403484.73150-0.322805.549704.21580HepG2HDGF
KARSENSG00000065427.102235.162903734.08700-0.7404014.1629012.88140HepG2HNRNPA1
KARSENSG00000065427.101855.814204153.40000-1.1622031.7853029.73870HepG2HNRNPC
KARSENSG00000065427.103866.881105049.88130-0.385108.017506.87380HepG2HNRNPF
KARSENSG00000065427.105883.195604678.520200.330403.145402.40170HepG2HNRNPK
KARSENSG00000065427.104340.129205099.28390-0.232604.756003.88930HepG2HNRNPL
KARSENSG00000065427.102430.253803122.77930-0.361703.120202.45660HepG2HNRNPLL
KARSENSG00000065427.102737.443504125.94620-0.5919018.6837017.21720HepG2HNRNPU
KARSENSG00000065427.103764.670004972.65170-0.401506.338005.28560HepG2IGF2BP1
KARSENSG00000065427.103857.897204696.13670-0.283701.993001.41080HepG2IGF2BP2
KARSENSG00000065427.103631.568404214.53140-0.214803.874003.02150HepG2ILF2
KARSENSG00000065427.102499.259803438.62960-0.460303.138801.80370HepG2KRR1
KARSENSG00000065427.103091.812004982.27890-0.688409.163207.98130HepG2MAGOH
KARSENSG00000065427.103084.579003671.02250-0.251102.451401.68850HepG2MSI2
KARSENSG00000065427.101818.812703184.93250-0.808307.071705.48730HepG2MTPAP
KARSENSG00000065427.103283.206405128.10890-0.643307.781306.74500HepG2NCBP2
KARSENSG00000065427.103572.998105551.00000-0.6356015.2916013.57100HepG2NOL12
KARSENSG00000065427.102260.809202768.97540-0.292502.357101.66430HepG2NSUN2
KARSENSG00000065427.103032.146904566.76760-0.590806.829905.70360HepG2PABPC4
KARSENSG00000065427.103947.567104833.51980-0.292105.293904.49790HepG2PCBP1
KARSENSG00000065427.102757.652203917.44770-0.506503.298102.16720HepG2PCBP2
KARSENSG00000065427.101586.244402267.31820-0.515408.172706.15650HepG2PKM
KARSENSG00000065427.102824.757103680.02860-0.381606.312505.23140HepG2PPIL4
KARSENSG00000065427.102255.270202833.33350-0.329202.272101.53680HepG2PRPF8
KARSENSG00000065427.103129.636304918.28190-0.6522021.3974020.15260HepG2PTBP1
KARSENSG00000065427.103465.075005298.99190-0.6128010.766009.69330HepG2PUF60
KARSENSG00000065427.103458.261705621.03890-0.7008017.2833015.69950HepG2PUM2
KARSENSG00000065427.102666.253403717.98830-0.4797013.3436012.16700HepG2PUS1
KARSENSG00000065427.103335.711005326.63200-0.6752017.7687016.38070HepG2QKI
KARSENSG00000065427.106448.793705713.041200.174702.103801.63610HepG2RBM22
KARSENSG00000065427.103053.459504834.25670-0.6628013.2238011.81390HepG2RBM25
KARSENSG00000065427.104208.337205473.57990-0.379208.462807.61040HepG2NELFE
KARSENSG00000065427.103679.895305097.88780-0.4702012.6971011.52100HepG2RECQL
KARSENSG00000065427.104406.005305440.55550-0.304303.194002.46750HepG2RPLP0
KARSENSG00000065427.102503.731303713.40850-0.568703.879602.76260HepG2RPS10
KARSENSG00000065427.102152.631402667.86160-0.309602.996102.36030HepG2RPS19
KARSENSG00000065427.102499.335603587.83590-0.521606.125804.95970HepG2RPS2
KARSENSG00000065427.101974.031903233.78700-0.712106.648705.41680HepG2RPS3A
KARSENSG00000065427.102156.162002677.48550-0.312402.253801.40130HepG2SERBP1
KARSENSG00000065427.105411.816403904.042500.471003.528002.76320HepG2SF3A3
KARSENSG00000065427.102568.981403090.90730-0.266802.108901.48740HepG2SF3B1
KARSENSG00000065427.103600.467105120.57580-0.5081014.5361013.34390HepG2SF3B4
KARSENSG00000065427.103652.977105081.09110-0.4761016.2574014.81580HepG2SLBP
KARSENSG00000065427.103717.308204285.03540-0.205003.822803.08670HepG2SMN1
KARSENSG00000065427.101939.108903439.18620-0.826707.504406.20990HepG2SNRNP70
KARSENSG00000065427.104137.884905232.09000-0.338506.696805.78020HepG2SRSF5
KARSENSG00000065427.103741.276604961.47920-0.407206.931605.90980HepG2SRSF7
KARSENSG00000065427.102530.517204348.25060-0.7810033.1417031.64130HepG2SRSF9
KARSENSG00000065427.103642.045605602.59920-0.6213019.5174018.42050HepG2SSB
KARSENSG00000065427.102092.565502813.17130-0.426902.875301.75020HepG2STIP1
KARSENSG00000065427.104703.168405950.23590-0.339308.758207.75560HepG2SUCLG1
KARSENSG00000065427.101751.326003655.98650-1.0618017.5664016.11670HepG2SUPV3L1
KARSENSG00000065427.104167.722904804.07560-0.205002.309401.78900HepG2TAF15
KARSENSG00000065427.102195.119503043.86850-0.471605.411104.44660HepG2TARDBP
KARSENSG00000065427.103354.476004414.30250-0.396105.390104.23630HepG2TIA1
KARSENSG00000065427.101459.011204009.43310-1.4584062.8519061.06070HepG2TIAL1
KARSENSG00000065427.103199.775204044.94670-0.338206.543205.74150HepG2TRIM56
KARSENSG00000065427.102596.233405177.03700-0.9957028.9973026.10810HepG2TUFM
KARSENSG00000065427.102902.096103880.43020-0.419104.556603.76110HepG2U2AF1
KARSENSG00000065427.104182.307705479.90840-0.389903.380502.45570HepG2UBE2L3
KARSENSG00000065427.102671.491303462.29410-0.374108.013706.92830HepG2UPF1
KARSENSG00000065427.102504.279803348.00350-0.418902.431201.49390HepG2UPF2
KARSENSG00000065427.105480.076403342.700800.7131030.3186028.65530HepG2UTP3
KARSENSG00000065427.102805.914203598.91500-0.359102.767502.04250HepG2XRN2
KARSENSG00000065427.102238.298803650.90710-0.7059029.4015027.65020HepG2ZC3H8
KARSENSG00000065427.102805.098503776.85460-0.429102.832301.52080HepG2ZRANB2
KARSENSG00000065427.109016.472707448.061300.275605.395204.64450K562AGGF1
KARSENSG00000065427.107039.163809857.11630-0.485806.497005.65990K562AQR
KARSENSG00000065427.105361.516006248.44930-0.220902.964501.59820K562BCCIP
KARSENSG00000065427.104849.679806038.31030-0.316306.805505.27250K562BCLAF1
KARSENSG00000065427.103562.743104460.94960-0.324402.815901.93520K562BOP1
KARSENSG00000065427.102390.663003397.84150-0.507205.844704.16460K562CCAR1
KARSENSG00000065427.103554.606704743.29280-0.416205.947604.80230K562CPSF6
KARSENSG00000065427.103708.323004580.95830-0.304904.585703.17470K562CSTF2
KARSENSG00000065427.105927.747507084.46080-0.257203.928902.47070K562DDX21
KARSENSG00000065427.1010726.484609012.207700.251104.503103.69900K562DDX47
KARSENSG00000065427.102994.724203803.82990-0.345002.894301.53220K562DHX30
KARSENSG00000065427.1011435.116608339.955300.4553010.702008.74850K562DKC1
KARSENSG00000065427.102742.546303653.84940-0.413904.381702.66220K562DNAJC21
KARSENSG00000065427.104364.648705329.34020-0.288102.358801.51770K562EFTUD2
KARSENSG00000065427.104259.644904933.76060-0.212002.766001.55790K562EIF2S1
KARSENSG00000065427.105483.148908196.40760-0.5800016.7880015.23570K562EIF2S2
KARSENSG00000065427.106135.668904527.475000.438408.433907.04860K562EIF3G
KARSENSG00000065427.1010130.8402012869.13830-0.345206.570905.14580K562EIF4G2
KARSENSG00000065427.103332.547604826.14250-0.534206.901005.52510K562FMR1
KARSENSG00000065427.102776.953504090.57140-0.558806.441904.98910K562FTO
KARSENSG00000065427.106402.750504880.203500.391708.106007.13870K562FXR1
KARSENSG00000065427.103348.559104528.69600-0.435605.475704.36420K562GPKOW
KARSENSG00000065427.109368.8570010922.49280-0.221402.167801.49330K562GRSF1
KARSENSG00000065427.102754.506906035.67050-1.1317036.8847034.78290K562HNRNPC
KARSENSG00000065427.103975.215105390.25270-0.439305.882104.13600K562HNRNPF
KARSENSG00000065427.107431.409305581.524400.412902.876501.92520K562HNRNPM
KARSENSG00000065427.106173.841508664.10170-0.4889010.825409.08570K562HNRNPU
KARSENSG00000065427.102662.280203430.76330-0.365903.136101.55130K562KHDRBS1
KARSENSG00000065427.102833.117603866.89250-0.448803.303202.27350K562KRR1
KARSENSG00000065427.103571.306104420.50480-0.307803.221802.27360K562METAP2
KARSENSG00000065427.1010594.2928013717.34030-0.372703.924102.58240K562MSI2
KARSENSG00000065427.105616.141406758.65740-0.267205.257304.16840K562MTPAP
KARSENSG00000065427.106591.499707509.54730-0.188104.611103.67790K562NSUN2
KARSENSG00000065427.105679.440907447.20660-0.391003.564802.62090K562PCBP3
KARSENSG00000065427.104361.524705712.33220-0.389205.589604.45280K562POLR2G
KARSENSG00000065427.106193.263405186.057200.256002.081501.42700K562PRPF8
KARSENSG00000065427.103754.409305411.71980-0.527508.213506.48130K562PSIP1
KARSENSG00000065427.1010762.8354014041.29730-0.383604.618303.56820K562PUF60
KARSENSG00000065427.1012810.8428014934.44270-0.221302.339001.36470K562PUM1
KARSENSG00000065427.1010415.9797014633.49110-0.4905012.8187010.76920K562PUM2
KARSENSG00000065427.109808.813607686.335800.351703.870403.24330K562PUS1
KARSENSG00000065427.108991.210507488.774800.263703.570002.91010K562RBM15
KARSENSG00000065427.103861.815004938.01760-0.354704.700403.40560K562RCC2
KARSENSG00000065427.107263.202005282.708000.459204.416703.38090K562RPS19
KARSENSG00000065427.106505.198707409.89960-0.187902.407001.64220K562SF3A3
KARSENSG00000065427.102980.116004306.88240-0.531305.338303.95620K562SF3B1
KARSENSG00000065427.102731.903703742.47400-0.454105.057603.31490K562SLBP
KARSENSG00000065427.106608.238007591.59250-0.200103.928502.83260K562SRPK2
KARSENSG00000065427.103382.800304443.25310-0.393405.130003.62130K562SRSF4
KARSENSG00000065427.105412.205506321.92200-0.224102.875101.68250K562SRSF7
KARSENSG00000065427.103348.938705021.44790-0.584406.503004.89700K562SUPV3L1
KARSENSG00000065427.104389.331106016.21490-0.454905.101304.12560K562TARDBP
KARSENSG00000065427.104868.244505803.32400-0.253502.596701.80630K562TIA1
KARSENSG00000065427.103338.341805205.10570-0.640808.496406.78330K562TIAL1
KARSENSG00000065427.104424.747905530.33690-0.321803.348902.28870K562TRIM56
KARSENSG00000065427.103676.998005314.47230-0.531406.399504.77400K562UCHL5
KARSENSG00000065427.105786.845807962.52650-0.4604014.5439013.04850K562UPF1
KARSENSG00000065427.105615.939706813.29180-0.278802.982902.07510K562WDR3
KARSENSG00000065427.108176.420607084.969000.206603.757502.78140K562WDR43
KARSENSG00000065427.104176.385605411.44190-0.373803.394102.00990K562XRN2
KARSENSG00000065427.108048.7708011104.73990-0.464306.564905.14650K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for KARS is not available on ENCORE database.





15 RBPs can affect the splicing of KARS :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEKARSENSG00000065427.10chr16-756781807567821775675461756756217568147575681522-0.051000.000110.04905excludedK562IGF2BP2
SEKARSENSG00000065427.10chr16-7567818075678360756754617567562175681475756815220.125000.000030.08301includedK562FUS
SEKARSENSG00000065427.10chr16-7567818075678360756754617567562175681475756815220.084000.000170.01547includedHepG2RBM22
SEKARSENSG00000065427.10chr16-756740817567424775669809756699967567546175675621-0.085000.000000.00000excludedHepG2U2AF1
SEKARSENSG00000065427.10chr16-756781807567836075675461756756217568147575681522-0.081000.000320.03554excludedHepG2PRPF8
SEKARSENSG00000065427.10chr16-756703517567044575669809756699967567546175675621-0.212000.000000.00000excludedHepG2U2AF2
SEKARSENSG00000065427.10chr16-7567818075678360756754617567562175681475756815220.072000.002720.08857includedHepG2MATR3
SEKARSENSG00000065427.10chr16-756781807567836075675461756756217568147575681522-0.076000.003510.06740excludedHepG2SRSF1
SEKARSENSG00000065427.10chr16-7567818075678360756754617567562175681475756815220.084000.001530.04270includedHepG2SF3A3
SEKARSENSG00000065427.10chr16-7567818075678360756754617567562175681475756815220.101000.000060.01119includedHepG2SSB
SEKARSENSG00000065427.10chr16-756781807567836075675461756756217568147575681522-0.086000.000930.04544excludedHepG2PCBP1
SEKARSENSG00000065427.10chr16-7567818075678360756754617567562175681475756815220.096000.000170.03336includedHepG2KHSRP
SEKARSENSG00000065427.10chr16-756781807567836075675461756756217568147575681522-0.071000.002520.04101excludedK562HNRNPC
A3SSKARSENSG00000065427.10chr16-7566246675662646756624667566261075663312756634890.064000.000000.00000longerK562AQR
A3SSKARSENSG00000065427.10chr16-7566561975665790756656197566575375669577756697030.552000.000010.00007longerK562AQR
A3SSKARSENSG00000065427.10chr16-7567035175670472756703517567044575674081756742470.121000.000000.00000longerK562AQR
MXEKARSENSG00000065427.10chr16-7567035175670445756740817567424775669809756699967567546175675621-0.073000.004500.066802includedHepG2U2AF1
MXEKARSENSG00000065427.10chr16-75665065756651517566531375665500756643207566440675665590756657900.063000.000000.000001includedK562AQR
MXEKARSENSG00000065427.10chr16-7567035175670445756740817567424775669809756699967567546175675621-0.090000.003000.083172includedHepG2SF3B4

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for KARS is not avaliable on ENCORE database.