ISM2

General Information

Gene Name       : ISM2
Gene ID             : ENSG00000100593.17
Essential Gene : No

Functions

Localization

Domains (AlphaFold: ISM2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878ISM2ENSG00000100593.170.000.010.01ENCSR000AEF
HepG2ISM2ENSG00000100593.1723.2011.1917.20ENCSR985KAT
K562ISM2ENSG00000100593.170.000.000.00ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for ISM2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • ISM2 RNA is bound by 5 proteins.  







eCLIP assay for ISM2 is not avaliable on ENCORE database.





5 proteins are bound to ISM2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr147794126477941329-3'-UTR,intron-Distal6.2772315.72143HepG2UPF1
chr147794136577941437-3'-UTR,intron-Distal5.7159324.07196HepG2AKAP1
chr147794136577941459-3'-UTR,intron-Distal5.5104829.11344HepG2UPF1
chr147794155677941636-3'-UTR,intron-Distal,intron-Proximal5.4144618.84814HepG2AKAP1
chr147794127877941327-3'-UTR,intron-Distal4.6537911.70635HepG2AKAP1
chr147794083677940885-3'-UTR,intron-Distal4.223774.03377HepG2LARP4
chr147794178677941869-3'-UTR,intron-Distal4.6452518.57875HepG2AKAP1
chr147794144577941538-3'-UTR,intron-Distal,intron-Proximal5.4284318.57108HepG2AKAP1
chr147794110277941158-3'-UTR,intron-Distal5.9053114.73409HepG2AKAP1
chr147794188277941932-3'-UTR,intron-Distal4.611718.16501HepG2UPF1
chr147794115877941248-3'-UTR,intron-Distal7.2988735.60720HepG2AKAP1
chr147794119277941251-3'-UTR,intron-Distal5.1854924.23241HepG2UPF1
chr147794159277941695-3'-UTR,intron-Distal7.4477336.82126HepG2UPF1
chr147794177977941868-3'-UTR,intron-Distal4.2741113.26890HepG2UPF1
chr147794169577941760-3'-UTR,intron-Distal5.1863120.37492HepG2UPF1
chr147794114877941192-3'-UTR,intron-Distal4.5260516.73159HepG2UPF1
chr147794145977941537-3'-UTR,intron-Distal,intron-Proximal5.6449721.86312HepG2UPF1
chr147794874177948781-3'-UTR,CDS,intron-Distal,intron-Proximal4.422593.38968HepG2BCLAF1
chr147794163877941687-3'-UTR,intron-Distal6.0161116.94078HepG2AKAP1
chr147794097877941047-3'-UTR,intron-Distal5.9820013.90466HepG2AKAP1
chr147794086077940936-3'-UTR,intron-Distal3.8172312.71052HepG2AKAP1
chr147794168777941757-3'-UTR,intron-Distal6.6773426.26245HepG2AKAP1
chr147794997277950041-intron-Distal3.846844.51074HepG2HNRNPL
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for ISM2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for ISM2 is not available on ENCORE database.

  • 128 RBPs can affect the levels of ISM2.  








The Knockdown/knockout RNA-Seq assay for ISM2 is not available on ENCORE database.





128 RBPs can affect the gene expression of ISM2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
ISM2ENSG00000100593.13128.142301309.67090-3.353405.088703.85090HepG2ABCF1
ISM2ENSG00000100593.13482.851701526.17620-1.6603016.7270015.49840HepG2ACO1
ISM2ENSG00000100593.13627.591602284.62090-1.864105.658604.92950HepG2AKAP1
ISM2ENSG00000100593.13627.489701890.08140-1.590804.753603.73590HepG2ASCC1
ISM2ENSG00000100593.132502.415901373.104800.8658014.1820012.84060HepG2AUH
ISM2ENSG00000100593.13384.04530564.57290-0.555903.716202.63130HepG2BCCIP
ISM2ENSG00000100593.131206.799101616.05540-0.421302.568901.63460HepG2CCAR1
ISM2ENSG00000100593.13371.204801795.78840-2.274307.314306.10350HepG2CIRBP
ISM2ENSG00000100593.13518.646501525.46460-1.5564017.9052016.53600HepG2CKAP4
ISM2ENSG00000100593.13650.50430310.788601.065505.308904.38530HepG2CPSF6
ISM2ENSG00000100593.132149.467201077.144200.996704.544303.15190HepG2CPSF7
ISM2ENSG00000100593.131064.56310783.152000.442805.183303.78810HepG2YBX3
ISM2ENSG00000100593.13224.87570348.62750-0.632604.161802.87270HepG2CSTF2
ISM2ENSG00000100593.134128.586601464.885701.494806.512005.60510HepG2CELF1
ISM2ENSG00000100593.132103.602101575.025300.417409.321108.08700HepG2DAZAP1
ISM2ENSG00000100593.13414.539201411.31970-1.7675020.4635018.69490HepG2DDX19B
ISM2ENSG00000100593.131052.97120784.230500.425004.571103.10270HepG2DDX1
ISM2ENSG00000100593.13484.613201077.57930-1.152903.226702.49790HepG2DDX21
ISM2ENSG00000100593.13423.208801056.51360-1.319903.432102.40980HepG2DDX24
ISM2ENSG00000100593.13229.65360519.31970-1.177206.125704.29360HepG2DDX27
ISM2ENSG00000100593.13875.78200555.130700.657602.417801.68990HepG2DDX55
ISM2ENSG00000100593.131010.74080352.934901.5178010.772708.93110HepG2DDX59
ISM2ENSG00000100593.136027.470701880.766301.6801030.3893028.67260HepG2DDX6
ISM2ENSG00000100593.13111.429901460.03880-3.7118048.8962046.97080HepG2DKC1
ISM2ENSG00000100593.131803.54980768.976501.2297040.9271038.65070HepG2DNAJC21
ISM2ENSG00000100593.13329.210901106.27460-1.7486031.3414028.93570HepG2EEF2
ISM2ENSG00000100593.13650.57580922.08310-0.503202.981801.83200HepG2EFTUD2
ISM2ENSG00000100593.136942.909901806.769001.9420041.1471039.06660HepG2EIF2S1
ISM2ENSG00000100593.13571.41700897.95050-0.652106.108004.80170HepG2EIF3D
ISM2ENSG00000100593.13255.951801018.94670-1.993105.818704.33670HepG2EIF3G
ISM2ENSG00000100593.131252.869202090.70400-0.738804.786002.40620HepG2EIF3H
ISM2ENSG00000100593.13472.212201996.08400-2.079706.751205.75000HepG2EIF4A3
ISM2ENSG00000100593.13594.482201944.62870-1.709805.234304.30890HepG2EIF4B
ISM2ENSG00000100593.13959.895201553.93360-0.6950014.7708013.14080HepG2EIF4G1
ISM2ENSG00000100593.132490.827401488.555600.742607.415906.10980HepG2EIF4G2
ISM2ENSG00000100593.13389.457601133.61310-1.541403.007601.87260HepG2ESF1
ISM2ENSG00000100593.13402.607001576.29620-1.9691011.7846010.68530HepG2ETF1
ISM2ENSG00000100593.13404.941701491.00960-1.8805015.3996013.51980HepG2EWSR1
ISM2ENSG00000100593.131683.91570802.738501.0687015.5036012.80740HepG2FAM120A
ISM2ENSG00000100593.13739.72120462.016900.678904.747803.12160HepG2FKBP4
ISM2ENSG00000100593.132405.113201509.278900.672103.655902.76090HepG2FUBP3
ISM2ENSG00000100593.131537.714501113.903300.465102.756101.64330HepG2FUS
ISM2ENSG00000100593.13743.602402015.80540-1.438804.078203.24970HepG2FXR1
ISM2ENSG00000100593.13510.461401985.43420-1.959605.980704.65920HepG2G3BP2
ISM2ENSG00000100593.13198.74450799.47990-2.0081039.0161036.29760HepG2GEMIN5
ISM2ENSG00000100593.13352.98930792.30630-1.1664015.8124013.38650HepG2GNB2L1
ISM2ENSG00000100593.131514.026401050.042200.527803.106001.43350HepG2GTF2F1
ISM2ENSG00000100593.132218.113801456.830900.6064010.227508.50820HepG2HDGF
ISM2ENSG00000100593.13705.197101068.37660-0.599303.096901.63030HepG2HLTF
ISM2ENSG00000100593.13133.75670776.34380-2.5371056.5334054.40640HepG2HNRNPA1
ISM2ENSG00000100593.131755.715501447.535100.278403.381902.36260HepG2HNRNPA2B1
ISM2ENSG00000100593.13409.82560863.54870-1.075308.692307.51650HepG2HNRNPC
ISM2ENSG00000100593.13677.33530359.417400.914102.442201.76610HepG2HNRNPF
ISM2ENSG00000100593.132062.394601434.701300.5235010.314209.09010HepG2HNRNPL
ISM2ENSG00000100593.13945.88490336.126401.492607.072106.11910HepG2HNRNPLL
ISM2ENSG00000100593.13395.65570911.43400-1.203902.292301.42830HepG2HNRNPM
ISM2ENSG00000100593.131095.891102429.84730-1.1488017.1760014.37260HepG2HSPD1
ISM2ENSG00000100593.131848.80450876.252101.0771011.9970010.59460HepG2ILF2
ISM2ENSG00000100593.131144.562302428.10470-1.085005.407903.65600HepG2KRR1
ISM2ENSG00000100593.13514.589601706.81270-1.7298030.8002028.00910HepG2LARP4
ISM2ENSG00000100593.13399.55750814.96420-1.0283014.1921011.65370HepG2LIN28B
ISM2ENSG00000100593.13528.63930778.69200-0.558804.585502.43000HepG2LSM11
ISM2ENSG00000100593.13249.500002016.51730-3.014809.842308.62460HepG2MAGOH
ISM2ENSG00000100593.13391.03070657.22310-0.749103.410201.63350HepG2MARK2
ISM2ENSG00000100593.13381.556702027.50420-2.409707.722906.71070HepG2MATR3
ISM2ENSG00000100593.131812.87550897.778901.013703.348702.00900HepG2NAA15
ISM2ENSG00000100593.13517.36430298.110000.795202.182401.51560HepG2NSUN2
ISM2ENSG00000100593.135373.835902159.562201.315102.839701.93790HepG2PABPC1
ISM2ENSG00000100593.133613.715101846.822600.968308.281007.04590HepG2PABPC4
ISM2ENSG00000100593.13668.318701996.14400-1.578608.060007.11320HepG2PCBP1
ISM2ENSG00000100593.13442.416701054.41140-1.2530013.4547011.44080HepG2PCBP2
ISM2ENSG00000100593.132035.863001451.172900.488303.598901.61610HepG2PES1
ISM2ENSG00000100593.13244.339501108.39070-2.1815034.0036030.63190HepG2PRPF6
ISM2ENSG00000100593.1393.34280428.03290-2.1971029.4701027.29330HepG2PRPF8
ISM2ENSG00000100593.13652.967902031.44810-1.637407.906807.07870HepG2PTBP1
ISM2ENSG00000100593.13860.572001490.89540-0.7928012.3538011.21370HepG2PUF60
ISM2ENSG00000100593.131016.658401582.67920-0.6385012.7235011.64850HepG2PUM1
ISM2ENSG00000100593.133300.196701581.505801.0612033.1614031.03430HepG2PUM2
ISM2ENSG00000100593.13335.557801554.45380-2.2118025.6452024.11980HepG2PUS1
ISM2ENSG00000100593.13571.205501017.34990-0.832705.238004.28460HepG2RAVER1
ISM2ENSG00000100593.131736.15690516.760301.748205.978102.57490HepG2RBFOX2
ISM2ENSG00000100593.133591.028202006.667900.8395022.3839020.36100HepG2RBM15
ISM2ENSG00000100593.13340.594401317.53610-1.9517012.7048011.75690HepG2RBM22
ISM2ENSG00000100593.133090.393701996.404600.630304.233803.41430HepG2RBM25
ISM2ENSG00000100593.13428.58230936.25910-1.1273010.791908.81430HepG2RBM27
ISM2ENSG00000100593.13544.41130760.28680-0.481803.229302.08240HepG2RCC2
ISM2ENSG00000100593.13431.884902260.56000-2.3880013.2264012.20340HepG2NELFE
ISM2ENSG00000100593.13728.990102105.85200-1.530407.504006.56180HepG2RECQL
ISM2ENSG00000100593.13149.80290387.26560-1.3703014.9952013.64470HepG2RPLP0
ISM2ENSG00000100593.13556.88650999.67920-0.844106.436905.03930HepG2RPS10
ISM2ENSG00000100593.13145.56610873.84450-2.5857050.9025048.88740HepG2RPS19
ISM2ENSG00000100593.13193.39630863.42240-2.1585032.5150030.01570HepG2RPS2
ISM2ENSG00000100593.13588.958502375.03890-2.011703.552202.64450HepG2RPS3A
ISM2ENSG00000100593.13249.84290423.39290-0.761005.211904.16480HepG2RRP9
ISM2ENSG00000100593.131069.67010763.937600.485507.416306.43510HepG2SAFB2
ISM2ENSG00000100593.13238.23440529.35010-1.151802.846901.47270HepG2SF1
ISM2ENSG00000100593.13211.57090988.88100-2.2247034.5569032.15540HepG2SF3A3
ISM2ENSG00000100593.131184.843302114.46720-0.835602.536601.96640HepG2SF3B4
ISM2ENSG00000100593.132737.604801429.593700.9372043.9575041.86840HepG2SLBP
ISM2ENSG00000100593.13575.71770890.87060-0.6299010.901009.75920HepG2SMN1
ISM2ENSG00000100593.131646.45330990.952700.732406.607304.10890HepG2SND1
ISM2ENSG00000100593.131218.24900473.400601.363605.696303.63430HepG2SNRNP200
ISM2ENSG00000100593.133643.294301488.186601.2916039.0469037.73450HepG2SRFBP1
ISM2ENSG00000100593.13765.29850528.663900.533602.995501.31060HepG2SRP68
ISM2ENSG00000100593.13135.700902207.26330-4.0238024.9186023.80890HepG2SRSF1
ISM2ENSG00000100593.13891.560001472.07550-0.723406.517905.61210HepG2SRSF5
ISM2ENSG00000100593.13570.28290353.135300.691405.190304.28400HepG2SRSF7
ISM2ENSG00000100593.13117.049101292.23470-3.4647025.1703023.96980HepG2SSB
ISM2ENSG00000100593.131318.876102421.34560-0.8765011.694009.33300HepG2SSRP1
ISM2ENSG00000100593.131422.09140950.787400.580702.833701.61620HepG2SUB1
ISM2ENSG00000100593.13833.950901674.12670-1.0054026.5109024.90980HepG2SUCLG1
ISM2ENSG00000100593.132338.34350891.695501.390807.577906.07480HepG2SUPT6H
ISM2ENSG00000100593.13175.04230552.56440-1.6584019.2207017.71350HepG2SUPV3L1
ISM2ENSG00000100593.13814.154801984.57750-1.285505.386904.64800HepG2TAF15
ISM2ENSG00000100593.13190.980602378.29650-3.6384057.4537053.77430HepG2TBRG4
ISM2ENSG00000100593.13714.81980370.328200.948704.491003.26710HepG2TFIP11
ISM2ENSG00000100593.132718.929701822.916400.576703.493202.55820HepG2TIA1
ISM2ENSG00000100593.13125.62130833.51410-2.7301080.5953078.59760HepG2TIAL1
ISM2ENSG00000100593.132630.36380841.004301.6450029.5179027.91770HepG2TRIM56
ISM2ENSG00000100593.13445.92990713.46410-0.678004.440502.46220HepG2TROVE2
ISM2ENSG00000100593.13376.214301130.29950-1.587102.930902.28540HepG2U2AF1
ISM2ENSG00000100593.13224.53140505.82270-1.171709.463307.55570HepG2UPF2
ISM2ENSG00000100593.13352.45630901.39190-1.354708.387306.67860HepG2UTP18
ISM2ENSG00000100593.13171.72280846.69340-2.3018036.5050034.70000HepG2UTP3
ISM2ENSG00000100593.13345.798001118.99260-1.6942024.2775021.59790HepG2XRCC6
ISM2ENSG00000100593.13191.69010543.94090-1.5047016.3471014.61340HepG2XRN2
ISM2ENSG00000100593.13360.03710839.48520-1.221403.507702.76520HepG2ZC3H8
ISM2ENSG00000100593.13664.418201016.74270-0.613804.305602.66000HepG2ZRANB2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for ISM2 is not available on ENCORE database.





15 RBPs can affect the splicing of ISM2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEISM2ENSG00000100593.13chr14-779486647794901077944917779450587795066577950908-0.090000.000240.01979excludedHepG2NCBP2
SEISM2ENSG00000100593.13chr14-779486647794901077944917779450587795066577950908-0.619000.000000.00000excludedHepG2SRSF1
SEISM2ENSG00000100593.13chr14-779486647794901077944917779450587795066577950908-0.104000.000420.02455excludedHepG2PCBP1
MXEISM2ENSG00000100593.13chr14-77950665779509087795101977951262779486647794901077964995779652100.269000.001730.045391includedHepG2MATR3
MXEISM2ENSG00000100593.13chr14-7795066577950908779510197795126277948664779490107796499577965210-0.225000.000320.014922includedHepG2TAF15
MXEISM2ENSG00000100593.13chr14-77950665779509087795101977951262779486647794901077964995779652100.288000.000000.000001includedHepG2SFPQ
MXEISM2ENSG00000100593.13chr14-77950665779509087795101977951262779486647794901077964995779652100.155000.001020.066111includedHepG2NOL12
MXEISM2ENSG00000100593.13chr14-77950665779509087795101977951262779486647794901077964995779652100.219000.000240.002441includedHepG2U2AF2
MXEISM2ENSG00000100593.13chr14-77950665779509087795101977951262779486647794901077964995779652100.187000.000010.001351includedHepG2RBFOX2
MXEISM2ENSG00000100593.13chr14-77950665779509087795101977951262779486647794901077964995779652100.223000.000010.000371includedHepG2HNRNPUL1
MXEISM2ENSG00000100593.13chr14-77950665779509087795101977951262779486647794901077964995779652100.197000.000010.001441includedHepG2DDX3X
MXEISM2ENSG00000100593.13chr14-77950665779509087795101977951262779486647794901077964995779652100.218000.000670.041901includedHepG2LARP4
MXEISM2ENSG00000100593.13chr14-77950665779509087795101977951262779486647794901077964995779652100.130000.002860.089461includedHepG2HNRNPL
MXEISM2ENSG00000100593.13chr14-77948664779490107795066577950908779449177794505877951019779512620.150000.001320.073951includedHepG2G3BP1
MXEISM2ENSG00000100593.13chr14-77950665779509087795101977951262779486647794901077964995779652100.252000.000000.000001includedHepG2NCBP2
MXEISM2ENSG00000100593.13chr14-77950665779509087795101977951262779486647794901077964995779652100.121000.002150.080561includedHepG2DDX6

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for ISM2 is not avaliable on ENCORE database.