HLA-B

General Information

Gene Name       : HLA-B
Gene ID             : ENSG00000234745.10
Essential Gene : No

Functions

Localization

Domains (AlphaFold: HLA-B)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878HLA-BENSG00000234745.101255.871435.961345.91ENCSR000AEF
HepG2HLA-BENSG00000234745.1052.5544.8448.70ENCSR985KAT
K562HLA-BENSG00000234745.100.400.110.26ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for HLA-B is not avaliable on ENCORE database.



Proteins bound to RNA
  • HLA-B RNA is bound by 9 proteins.  







eCLIP assay for HLA-B is not avaliable on ENCORE database.





9 proteins are bound to HLA-B RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr63132169031321737-3'-UTR,intron-Distal3.257518.01683HepG2LARP4
chr63132173731321794-3'-UTR,intron-Distal3.6048324.84312HepG2LARP4
chr63132168931321742-3'-UTR,intron-Distal3.637554.70109HepG2ZC3H11A
chr63132174031321805-3'-UTR,intron-Distal3.6640015.64514HepG2DDX55
chr63132178031321851-3'-UTR,intron-Distal4.407914.13513HepG2LIN28B
chr63132174131321893-3'-UTR,intron-Distal4.404045.07111HepG2UPF1
chr63132179331321855-3'-UTR,intron-Distal4.455669.14792HepG2PCBP2
chr63132180531321880-3'-UTR,intron-Distal3.3251713.22396HepG2DDX55
chr63132185531321915-3'-UTR,intron-Distal4.3182117.26981HepG2PCBP2
chr63132179431321858-3'-UTR,intron-Distal3.5659432.73304HepG2LARP4
chr63132486131324890-5'-UTR,CDS,intron-Distal4.118308.83932HepG2DDX3X
chr63132405131324118-CDS,intron-Distal4.2111958.16060HepG2SND1
chr63132291231322962-CDS,intron-Distal,intron-Proximal3.6519710.81522HepG2SND1
chr63132415031324194-CDS,intron-Distal5.7369833.12253HepG2SND1
chr63132322031323286-CDS,intron-Distal,intron-Proximal4.5199929.60620HepG2SND1
chr63132314431323197-CDS,intron-Distal,intron-Proximal4.6859318.26109HepG2SND1
chr63132226231322300-CDS,intron-Distal,intron-Proximal3.557587.54912HepG2SND1
chr63132419431324219-CDS,intron-Distal5.3813624.22457HepG2SND1
chr63132298031323000-CDS,intron-Distal,intron-Proximal4.5395213.28274HepG2SND1
chr63132322631323291-CDS,intron-Distal,intron-Proximal3.722216.10841HepG2RPS3
chr63132309231323127-CDS,intron-Distal,intron-Proximal3.837876.43771HepG2RPS3
chr63132411931324150-CDS,intron-Distal4.6384127.59341HepG2SND1
chr63132469831324736-CDS,intron-Distal,intron-Proximal3.890206.95142HepG2DDX3X
chr63132447131324509-CDS,intron-Distal4.4717525.94131HepG2SND1
chr63132413031324196-CDS,intron-Distal4.326517.46994HepG2RPS3
chr63132226231322295-CDS,intron-Distal,intron-Proximal3.402558.05774HepG2LARP4
chr63132309331323135-CDS,intron-Distal,intron-Proximal5.7060821.92940HepG2SND1
chr63132446331324471-CDS,intron-Distal,intron-Proximal5.0358125.82197HepG2SND1
chr63132401131324051-CDS,intron-Distal4.1075118.09740HepG2SND1
chr63132401331324130-CDS,intron-Distal3.6300017.37328HepG2RPS3
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for HLA-B is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for HLA-B is not available on ENCORE database.

  • 114 RBPs can affect the levels of HLA-B.  








The Knockdown/knockout RNA-Seq assay for HLA-B is not available on ENCORE database.





114 RBPs can affect the gene expression of HLA-B :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
HLA-BENSG00000234745.5381.96200659.32790-0.787607.894806.19590HepG2AATF
HLA-BENSG00000234745.51288.917201117.528600.205701.958701.43050HepG2ACO1
HLA-BENSG00000234745.5600.86970456.191400.397302.358501.43560HepG2ADAR
HLA-BENSG00000234745.51931.478201140.892200.759408.489806.77120HepG2AKAP8
HLA-BENSG00000234745.51930.423801122.816800.7817015.5165013.90680HepG2AKAP8L
HLA-BENSG00000234745.5502.879401008.59900-1.004103.735701.80570HepG2APOBEC3C
HLA-BENSG00000234745.52519.988301343.955400.9068014.0296012.38890HepG2ASCC1
HLA-BENSG00000234745.51445.92510778.837000.892507.656105.44610HepG2ATP5C1
HLA-BENSG00000234745.51713.71960948.999600.852609.532508.38630HepG2AUH
HLA-BENSG00000234745.5708.00740393.876100.845907.893706.47050HepG2BCLAF1
HLA-BENSG00000234745.5803.07040186.808702.1039024.1874022.69650HepG2BOP1
HLA-BENSG00000234745.51378.49680646.818901.0916018.9624016.11820HepG2BUD13
HLA-BENSG00000234745.5512.26370368.851200.473703.502702.64940HepG2CALR
HLA-BENSG00000234745.51456.86390829.767900.812007.706806.06100HepG2CCAR1
HLA-BENSG00000234745.5958.751401276.87070-0.413403.130202.31000HepG2CIRBP
HLA-BENSG00000234745.5596.37910171.481801.798107.611106.51700HepG2CPSF6
HLA-BENSG00000234745.52049.30810832.303101.2999066.5931063.98570HepG2DAZAP1
HLA-BENSG00000234745.5789.616101033.57470-0.388403.179302.29010HepG2DDX19B
HLA-BENSG00000234745.5867.10320468.482500.8881013.0321010.81660HepG2DDX1
HLA-BENSG00000234745.51006.57490711.755000.499905.160803.90420HepG2DDX24
HLA-BENSG00000234745.53391.599701555.874701.1241021.1047019.54420HepG2DDX3X
HLA-BENSG00000234745.51542.93750951.143400.697809.386707.18720HepG2DDX47
HLA-BENSG00000234745.5760.37600558.392400.445303.391801.89050HepG2DDX52
HLA-BENSG00000234745.52476.217001336.849300.8892011.4282010.27380HepG2DDX6
HLA-BENSG00000234745.5889.80010443.064101.0059014.9724012.98550HepG2DHX30
HLA-BENSG00000234745.51834.594701069.183700.778908.654107.58940HepG2DKC1
HLA-BENSG00000234745.5847.83740455.278600.8969019.6027018.01790HepG2DNAJC2
HLA-BENSG00000234745.51206.72860669.717000.849408.365006.50540HepG2AGO1
HLA-BENSG00000234745.52200.807401284.827400.7764010.199809.10390HepG2EIF2S1
HLA-BENSG00000234745.5327.10180540.63680-0.724904.874703.70070HepG2EIF3D
HLA-BENSG00000234745.5783.810501382.60150-0.818807.124106.04750HepG2EIF4B
HLA-BENSG00000234745.51141.41590786.644400.536905.299604.19180HepG2EIF4G2
HLA-BENSG00000234745.5898.928301089.57380-0.277502.754802.15540HepG2ETF1
HLA-BENSG00000234745.5911.09250483.354200.9144014.5262011.91700HepG2FAM120A
HLA-BENSG00000234745.5614.83210872.15640-0.504401.967001.31150HepG2FIP1L1
HLA-BENSG00000234745.5849.225501432.91530-0.754708.749707.58030HepG2FXR1
HLA-BENSG00000234745.5522.26540194.336501.4261011.052609.83760HepG2GPKOW
HLA-BENSG00000234745.51397.79170655.870301.091608.857105.95700HepG2GRWD1
HLA-BENSG00000234745.51486.253201066.947400.478108.034806.48190HepG2HDGF
HLA-BENSG00000234745.51085.08380463.784601.2262022.3530020.82050HepG2HNRNPA1
HLA-BENSG00000234745.5904.55320336.005001.4286036.1744034.08990HepG2HNRNPF
HLA-BENSG00000234745.5515.47450185.463501.4747013.8720012.60820HepG2HNRNPLL
HLA-BENSG00000234745.5343.85470601.47670-0.806704.245703.09230HepG2HNRNPM
HLA-BENSG00000234745.5833.17220512.449000.7011011.1559010.00710HepG2HNRNPU
HLA-BENSG00000234745.51153.67200330.862201.8018050.0909047.68920HepG2IGF2BP1
HLA-BENSG00000234745.51676.186901350.806100.311302.062901.47060HepG2IGF2BP2
HLA-BENSG00000234745.5678.25810523.452400.373703.806102.95950HepG2ILF2
HLA-BENSG00000234745.51714.807301052.904000.703605.456803.56910HepG2ILF3
HLA-BENSG00000234745.51402.975701029.828500.446002.922601.69260HepG2KHDRBS1
HLA-BENSG00000234745.51598.769901021.589500.6460016.8785014.62960HepG2KIF1C
HLA-BENSG00000234745.53083.463801241.168201.3128019.7643016.63720HepG2KRR1
HLA-BENSG00000234745.5799.734901433.41760-0.8419010.387509.14180HepG2MAGOH
HLA-BENSG00000234745.5773.95230189.261302.031808.209506.50910HepG2MTPAP
HLA-BENSG00000234745.52392.870901475.255100.697708.019806.96750HepG2NCBP2
HLA-BENSG00000234745.51398.53020825.315300.7608014.4806012.80100HepG2NOL12
HLA-BENSG00000234745.5279.01110164.486300.762302.345401.65420HepG2NSUN2
HLA-BENSG00000234745.5705.97390987.27050-0.483802.114101.35350HepG2PABPC1
HLA-BENSG00000234745.52396.607701313.527800.8674012.3943010.89620HepG2PABPC4
HLA-BENSG00000234745.51582.991101062.778600.574706.102903.57610HepG2PES1
HLA-BENSG00000234745.51144.70250457.066401.3244036.2177033.82750HepG2PPIL4
HLA-BENSG00000234745.5496.07990343.853300.528703.298902.42440HepG2PRPF8
HLA-BENSG00000234745.51330.62020789.906600.752204.149801.97070HepG2PSIP1
HLA-BENSG00000234745.5865.348701338.54540-0.6293012.0631011.08070HepG2PTBP1
HLA-BENSG00000234745.51129.04630787.862800.519003.318702.67450HepG2PUF60
HLA-BENSG00000234745.52051.76180835.752301.2956040.3605038.07780HepG2PUM2
HLA-BENSG00000234745.51695.787501138.282000.5750012.8585011.69660HepG2PUS1
HLA-BENSG00000234745.51690.767001449.669600.221901.824801.30140HepG2QKI
HLA-BENSG00000234745.5233.17730698.20210-1.5822013.8473012.37930HepG2RAVER1
HLA-BENSG00000234745.51515.345701103.233200.457802.694501.84630HepG2RBM15
HLA-BENSG00000234745.5788.977901315.67140-0.7377010.984209.70200HepG2RBM25
HLA-BENSG00000234745.51104.25920696.378400.665004.371001.78480HepG2RBM34
HLA-BENSG00000234745.51006.525101489.66930-0.565609.767108.86460HepG2NELFE
HLA-BENSG00000234745.51025.17870362.061601.5015010.606809.41970HepG2RPLP0
HLA-BENSG00000234745.51804.30690685.940901.3952017.5816015.46130HepG2RPS10
HLA-BENSG00000234745.51588.093201085.183100.549303.866802.92080HepG2RPS3A
HLA-BENSG00000234745.5659.52910456.368000.531106.141805.23970HepG2SAFB2
HLA-BENSG00000234745.5403.11900183.542501.135006.009805.00350HepG2SF3B1
HLA-BENSG00000234745.5979.883101393.59170-0.508108.107707.17810HepG2SF3B4
HLA-BENSG00000234745.51306.53040755.503000.7901020.9000019.32110HepG2SLBP
HLA-BENSG00000234745.51423.32000679.718801.0662012.406209.22060HepG2SND1
HLA-BENSG00000234745.5712.90030204.233901.8034010.437708.92830HepG2SNRNP70
HLA-BENSG00000234745.5695.846101028.58470-0.563808.685107.93310HepG2SRFBP1
HLA-BENSG00000234745.5608.75400424.470200.520103.396701.59540HepG2SRP68
HLA-BENSG00000234745.5588.350901454.61080-1.3059043.9667042.57960HepG2SRSF1
HLA-BENSG00000234745.51921.17200777.937901.304209.569308.49870HepG2SRSF5
HLA-BENSG00000234745.51063.94470330.137301.6882054.0913051.87930HepG2SRSF7
HLA-BENSG00000234745.51500.07860893.058100.7481018.1737017.10450HepG2SSB
HLA-BENSG00000234745.5954.88740652.500500.549302.892501.66230HepG2SUB1
HLA-BENSG00000234745.5931.27960588.548900.662005.001003.75620HepG2SUPT6H
HLA-BENSG00000234745.5854.43330443.644200.945509.700208.56230HepG2SUPV3L1
HLA-BENSG00000234745.51500.85150180.906103.0524093.4934090.46680HepG2TARDBP
HLA-BENSG00000234745.51678.154301201.377400.482106.035204.80730HepG2TIA1
HLA-BENSG00000234745.51063.09970701.149200.600403.333301.72990HepG2TRA2A
HLA-BENSG00000234745.5811.41200502.387200.6915010.664009.66450HepG2TRIM56
HLA-BENSG00000234745.5421.99220745.82550-0.821604.258103.48770HepG2U2AF1
HLA-BENSG00000234745.51447.70620814.813600.829109.463707.87620HepG2UBE2L3
HLA-BENSG00000234745.51610.64250815.316200.9821031.4260029.60640HepG2UPF1
HLA-BENSG00000234745.5572.91040406.306600.495602.454501.51240HepG2UPF2
HLA-BENSG00000234745.51233.28750838.031500.557308.790307.04750HepG2UTP18
HLA-BENSG00000234745.5609.24770787.15580-0.369603.677203.00300HepG2UTP3
HLA-BENSG00000234745.51676.35490972.047500.786107.181305.41710HepG2XPO5
HLA-BENSG00000234745.5399.95130686.66710-0.779805.067103.33900HepG2XRCC5
HLA-BENSG00000234745.5449.19790767.88760-0.773505.638604.15970HepG2XRCC6
HLA-BENSG00000234745.5787.09230436.718300.849708.612807.34980HepG2XRN2
HLA-BENSG00000234745.5553.51090349.173900.664602.741802.07250HepG2ZC3H8
HLA-BENSG00000234745.51092.75700896.691800.285203.297102.71530HepG2ZNF622
HLA-BENSG00000234745.51103.17810697.654700.661005.000703.19890HepG2ZRANB2
HLA-BENSG00000234745.576.2954027.874101.452603.460002.83840K562AGGF1
HLA-BENSG00000234745.567.0633029.007801.209003.618802.86810K562AKAP8L
HLA-BENSG00000234745.533.1476010.773901.621302.707301.61220K562CPEB4
HLA-BENSG00000234745.545.8521011.592601.983704.507703.61660K562EIF2S2
HLA-BENSG00000234745.517.385203.617802.264602.274201.50500K562FIP1L1
HLA-BENSG00000234745.583.0355015.446402.426407.912806.62300K562GRSF1
HLA-BENSG00000234745.527.553004.903402.490303.379502.50120K562HSPD1
HLA-BENSG00000234745.523.123304.108602.492503.035702.17110K562PPIG
HLA-BENSG00000234745.539.373908.688302.180004.277203.11830K562PSIP1
HLA-BENSG00000234745.562.6231028.742901.123402.562102.03520K562PUS1
HLA-BENSG00000234745.553.6350028.026200.936302.001401.48220K562RBM15
HLA-BENSG00000234745.533.849309.283701.866302.793801.97330K562RPS19
HLA-BENSG00000234745.527.459409.630701.511501.993901.30620K562TIA1
HLA-BENSG00000234745.556.7880029.962300.922302.088001.34910K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for HLA-B is not available on ENCORE database.






No RBPs affect the alternative splcing events of HLA-B on ENCORE database.





The Knockdown/knockout RNA-Seq assay for HLA-B is not avaliable on ENCORE database.