FBXO22

General Information

Gene Name       : FBXO22
Gene ID             : ENSG00000167196.13
Essential Gene : No

Functions

Localization

Domains (AlphaFold: FBXO22)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878FBXO22ENSG00000167196.1330.7328.4329.58ENCSR000AEF
HepG2FBXO22ENSG00000167196.1357.1471.8264.48ENCSR985KAT
K562FBXO22ENSG00000167196.1338.6044.7241.66ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for FBXO22 is not avaliable on ENCORE database.



Proteins bound to RNA
  • FBXO22 RNA is bound by 18 proteins.  







eCLIP assay for FBXO22 is not avaliable on ENCORE database.





18 proteins are bound to FBXO22 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr157622693976227013+3'-UTR3.319313.84340K562CSTF2T
chr157622233376222390+3'-UTR,CDS3.556564.94406K562YBX3
chr157622675976226834+3'-UTR4.231004.11729K562CPSF6
chr157622504876225160+3'-UTR,CDS,intron-Distal3.979873.61584HepG2SRSF1
chr157622520376225276+3'-UTR,CDS,intron-Distal4.568606.32937K562LIN28B
chr157622684176226890+3'-UTR3.247894.05586HepG2U2AF2
chr157622232376222431+3'-UTR,CDS,intron-Proximal3.029934.71502HepG2GRWD1
chr157622237176222489+3'-UTR,CDS,intron-Proximal3.749746.69500K562KHSRP
chr157622663576226746+3'-UTR3.6442211.94993HepG2GRWD1
chr157622261776222707+3'-UTR,intron-Distal3.353344.57751HepG2U2AF2
chr157622656576226813+3'-UTR4.814757.88111K562GRWD1
chr157619637776196438+5'-UTR,CDS4.214893.30242K562FTO
chr157619624376196445+5'-UTR,CDS,intron-Proximal4.4497433.79705K562DDX3X
chr157620641976206568+5'-UTR,CDS,intron-Distal,intron-Proximal3.113357.72751HepG2BUD13
chr157619627476196351+5'-UTR,CDS3.759724.32964K562HNRNPM
chr157619685976196963+5'-UTR,CDS,intron-Distal3.215673.22540HepG2G3BP1
chr157619695176197015+5'-UTR,CDS,intron-Distal,intron-Proximal3.814877.02084HepG2PRPF8
chr157619693676196971+5'-UTR,CDS,intron-Distal,intron-Proximal3.008884.87174HepG2PPIG
chr157620651076206570+5'-UTR,CDS,intron-Distal,intron-Proximal4.180264.75655HepG2PRPF8
chr157619638076196447+5'-UTR,CDS,intron-Proximal4.023906.64430HepG2PPIG
chr157619638176196442+5'-UTR,CDS5.038908.56126HepG2NCBP2
chr157619625876196381+5'-UTR,CDS4.1269815.55867HepG2NCBP2
chr157620434876204414+intron-Distal4.307473.30687K562EXOSC5
chr157620355576203596+intron-Distal4.841036.41304K562EXOSC5
chr157619851576198582+intron-Distal3.444223.91859HepG2SUGP2
chr157621766476217728+intron-Distal4.410484.90578HepG2HNRNPM
chr157619863176198706+intron-Distal3.239323.84025HepG2SUGP2
chr157622472976224867+intron-Distal3.9703712.08764K562KHSRP
chr157620494376205024+intron-Distal4.164773.59917K562EXOSC5
chr157621739776217500+intron-Distal3.538096.58367HepG2HNRNPM
chr157621944176219508+intron-Distal3.754573.66782HepG2HNRNPM
chr157622487376224921+intron-Distal3.911973.22073HepG2KHSRP
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for FBXO22 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for FBXO22 is not available on ENCORE database.

  • 103 RBPs can affect the levels of FBXO22.  








The Knockdown/knockout RNA-Seq assay for FBXO22 is not available on ENCORE database.





103 RBPs can affect the gene expression of FBXO22 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
FBXO22ENSG00000167196.91625.012401181.453900.459803.848702.74890HepG2ABCF1
FBXO22ENSG00000167196.91335.748201161.589500.201401.930201.40540HepG2ACO1
FBXO22ENSG00000167196.92252.799401389.699500.696807.159406.34830HepG2AKAP1
FBXO22ENSG00000167196.91278.39310917.859100.477903.690902.49860HepG2AKAP8
FBXO22ENSG00000167196.9762.065301023.07120-0.424902.413801.57580HepG2BCLAF1
FBXO22ENSG00000167196.91441.416301051.865400.454404.364203.63270HepG2BOP1
FBXO22ENSG00000167196.91506.903401161.418600.375606.133805.21460HepG2CKAP4
FBXO22ENSG00000167196.9650.41800965.67540-0.570205.252504.33360HepG2CPSF6
FBXO22ENSG00000167196.9624.06930973.22980-0.641106.810105.14780HepG2CPSF7
FBXO22ENSG00000167196.91246.36180727.325900.7769010.677508.79280HepG2CSTF2
FBXO22ENSG00000167196.91240.383701501.97470-0.276103.758102.91680HepG2DAZAP1
FBXO22ENSG00000167196.91451.14190869.907300.7382010.281009.06420HepG2DDX21
FBXO22ENSG00000167196.9682.03760950.51060-0.478905.609404.63810HepG2DNAJC21
FBXO22ENSG00000167196.9681.05680942.06870-0.468106.936605.96990HepG2DNAJC2
FBXO22ENSG00000167196.9723.170101099.36440-0.604305.368704.55990HepG2EIF2S1
FBXO22ENSG00000167196.91042.86140821.292100.344502.775901.69200HepG2EIF3G
FBXO22ENSG00000167196.92585.805502224.206400.217202.750002.15090HepG2ETF1
FBXO22ENSG00000167196.91490.369701135.152800.392702.258801.50460HepG2EWSR1
FBXO22ENSG00000167196.9559.18940735.24260-0.394902.162401.46010HepG2FUBP3
FBXO22ENSG00000167196.91372.64290991.600500.469002.726001.61690HepG2FUS
FBXO22ENSG00000167196.91705.606001225.707400.476604.182603.34510HepG2FXR1
FBXO22ENSG00000167196.9880.330601137.10460-0.369202.255301.65090HepG2G3BP1
FBXO22ENSG00000167196.9832.995401094.68370-0.394102.468501.86040HepG2GPKOW
FBXO22ENSG00000167196.9801.799701109.03490-0.468006.709005.27150HepG2HDGF
FBXO22ENSG00000167196.91162.813601368.22090-0.234702.825902.14650HepG2HNRNPL
FBXO22ENSG00000167196.91855.471601155.870800.682707.991206.90580HepG2IGF2BP2
FBXO22ENSG00000167196.9717.695201083.08850-0.5937012.1338010.72320HepG2ILF2
FBXO22ENSG00000167196.9896.484401061.88920-0.244302.476401.51180HepG2KIF1C
FBXO22ENSG00000167196.92577.979901233.022301.0639016.3920014.95300HepG2MATR3
FBXO22ENSG00000167196.9515.61690810.94240-0.653306.826704.94630HepG2NAA15
FBXO22ENSG00000167196.91267.72110938.698800.433402.258701.31780HepG2PCBP2
FBXO22ENSG00000167196.9722.94400945.72690-0.387503.921803.05990HepG2PPIL4
FBXO22ENSG00000167196.91708.95730986.808800.792206.349404.57200HepG2PRPF6
FBXO22ENSG00000167196.91181.71260893.132800.403803.128602.27500HepG2PRPF8
FBXO22ENSG00000167196.91350.062701111.447300.280503.136702.56130HepG2PTBP1
FBXO22ENSG00000167196.91445.800501183.166200.289103.557402.87720HepG2PUS1
FBXO22ENSG00000167196.92515.201201859.016700.436006.961406.22800HepG2RBM22
FBXO22ENSG00000167196.91361.351701092.471800.317302.581101.92670HepG2RBM25
FBXO22ENSG00000167196.91697.438301236.944500.456507.169706.36880HepG2NELFE
FBXO22ENSG00000167196.91444.210701152.026800.326003.830303.12120HepG2RECQL
FBXO22ENSG00000167196.92585.127601507.910200.7776013.7910012.48140HepG2RPLP0
FBXO22ENSG00000167196.91482.94700889.827500.736805.509404.19910HepG2RPS10
FBXO22ENSG00000167196.91015.23990700.414800.535405.461004.62950HepG2RPS19
FBXO22ENSG00000167196.92010.578501140.311300.8181012.6719011.05780HepG2RPS2
FBXO22ENSG00000167196.91552.783601192.175000.381202.090701.39460HepG2RPS3A
FBXO22ENSG00000167196.91229.84080883.513500.477003.764202.86500HepG2RRP9
FBXO22ENSG00000167196.91493.57150985.517500.599703.780101.98150HepG2RTF1
FBXO22ENSG00000167196.92032.772801285.669600.660805.534204.56140HepG2SF3A3
FBXO22ENSG00000167196.91793.245101157.182500.6319013.4452012.29630HepG2SF3B4
FBXO22ENSG00000167196.91165.283401363.08800-0.226202.556301.87850HepG2SLBP
FBXO22ENSG00000167196.92460.417002099.676400.228603.047702.52990HepG2SRFBP1
FBXO22ENSG00000167196.92584.056801207.838801.0971045.9568044.53960HepG2SRSF1
FBXO22ENSG00000167196.92004.403901403.654200.513907.175806.23250HepG2SRSF5
FBXO22ENSG00000167196.92507.148501822.990900.459609.944209.08750HepG2SSB
FBXO22ENSG00000167196.91478.35920995.698400.570104.967703.29900HepG2SSRP1
FBXO22ENSG00000167196.92053.256301596.382200.363006.166605.30610HepG2SUCLG1
FBXO22ENSG00000167196.91434.014901085.627200.401404.781304.07720HepG2TAF15
FBXO22ENSG00000167196.91891.491601030.363200.876309.452108.62480HepG2TIAL1
FBXO22ENSG00000167196.9848.787001039.50900-0.292403.063402.47710HepG2TRIM56
FBXO22ENSG00000167196.9814.468501020.71160-0.325601.937201.40070HepG2U2AF1
FBXO22ENSG00000167196.9624.239901173.86650-0.911102.617501.65950HepG2U2AF2
FBXO22ENSG00000167196.9869.44790680.766400.352802.370001.66680HepG2UCHL5
FBXO22ENSG00000167196.91354.647901140.192600.248502.681801.99200HepG2UPF1
FBXO22ENSG00000167196.91667.629101100.810800.5991012.3808011.25250HepG2UTP3
FBXO22ENSG00000167196.91749.74320996.214600.812507.266205.61640HepG2XRCC6
FBXO22ENSG00000167196.91040.76290741.043100.489907.394506.38390HepG2ZC3H8
FBXO22ENSG00000167196.9854.259101253.99330-0.5538011.2253010.30640HepG2ZNF622
FBXO22ENSG00000167196.91311.43000905.029000.535003.590102.09640HepG2ZRANB2
FBXO22ENSG00000167196.91544.883802359.63990-0.611108.327307.39770K562AQR
FBXO22ENSG00000167196.9776.422001088.39760-0.487303.661701.97780K562BUD13
FBXO22ENSG00000167196.9375.50580569.25640-0.600204.726703.26770K562CCAR1
FBXO22ENSG00000167196.9798.465201209.05440-0.598605.189203.13620K562CKAP4
FBXO22ENSG00000167196.91253.516901745.54660-0.477702.295401.34550K562CNOT7
FBXO22ENSG00000167196.9581.01810834.68130-0.522605.026203.97320K562CPSF6
FBXO22ENSG00000167196.9669.944601052.85220-0.652206.555105.10190K562EFTUD2
FBXO22ENSG00000167196.91288.982701570.11640-0.284602.321301.65400K562EIF2S2
FBXO22ENSG00000167196.9781.525101127.39310-0.528603.821802.58530K562EIF3D
FBXO22ENSG00000167196.9719.575701066.63870-0.567905.947304.75370K562EIF4A3
FBXO22ENSG00000167196.92091.560102746.03190-0.392806.248304.85360K562EIF4G2
FBXO22ENSG00000167196.9541.16400719.84270-0.411602.610201.72580K562FTO
FBXO22ENSG00000167196.9553.74330796.91170-0.525204.477003.47230K562GPKOW
FBXO22ENSG00000167196.9548.265401215.40280-1.1485022.0969020.49060K562HNRNPC
FBXO22ENSG00000167196.9787.100901085.25010-0.463404.298702.83980K562HNRNPF
FBXO22ENSG00000167196.91183.49360923.918700.357102.232301.40030K562HNRNPM
FBXO22ENSG00000167196.91016.209201289.12260-0.343202.755901.56830K562IGF2BP3
FBXO22ENSG00000167196.91073.034801593.02250-0.570102.907401.45060K562ILF2
FBXO22ENSG00000167196.9454.19790680.47250-0.583203.461502.40300K562KRR1
FBXO22ENSG00000167196.9874.197301176.64490-0.428603.754502.08130K562LARP7
FBXO22ENSG00000167196.91500.199001826.12910-0.283602.343901.51750K562MBNL1
FBXO22ENSG00000167196.9585.05460777.87620-0.411003.124202.19010K562METAP2
FBXO22ENSG00000167196.9980.257501279.97530-0.384902.167101.40790K562NAA15
FBXO22ENSG00000167196.91319.684001557.87320-0.239403.122502.33380K562NSUN2
FBXO22ENSG00000167196.9897.213801196.51710-0.415303.018401.50960K562NUSAP1
FBXO22ENSG00000167196.9849.692501267.47070-0.576902.311701.42320K562PABPN1
FBXO22ENSG00000167196.9913.710501185.27430-0.375403.079502.04790K562PCBP2
FBXO22ENSG00000167196.9873.292901186.52890-0.442203.640501.97730K562PHF6
FBXO22ENSG00000167196.9773.061201024.54360-0.406302.785102.03310K562PRPF8
FBXO22ENSG00000167196.9684.808401089.70640-0.670207.627905.98340K562PSIP1
FBXO22ENSG00000167196.92134.702402996.09870-0.489106.124204.91130K562PUF60
FBXO22ENSG00000167196.92353.199403122.44510-0.408107.084705.52130K562PUM2
FBXO22ENSG00000167196.9905.392001241.09070-0.455004.223103.15740K562RBM22
FBXO22ENSG00000167196.9875.052901559.38940-0.833503.788501.92030K562RBM39
FBXO22ENSG00000167196.9646.57000994.07360-0.620507.296005.67880K562RCC2
FBXO22ENSG00000167196.91260.800601537.25390-0.286002.861902.03540K562SF3A3
FBXO22ENSG00000167196.9557.63480757.90430-0.442702.653601.70000K562SF3B1
FBXO22ENSG00000167196.9670.718201331.09250-0.988805.249903.38460K562SNRNP200
FBXO22ENSG00000167196.9558.82400942.36990-0.753903.549502.34920K562SRFBP1
FBXO22ENSG00000167196.91303.637901574.95260-0.272803.463702.43100K562SRPK2
FBXO22ENSG00000167196.9935.619801268.73240-0.439404.442303.55060K562SRSF1
FBXO22ENSG00000167196.9560.71350738.25150-0.396802.768201.71690K562SRSF4
FBXO22ENSG00000167196.9642.55700992.11890-0.626705.206203.77480K562SUPV3L1
FBXO22ENSG00000167196.9971.747301284.08500-0.402103.210902.44940K562TARDBP
FBXO22ENSG00000167196.91007.145701238.63320-0.298502.346801.60030K562TIA1
FBXO22ENSG00000167196.9690.135101048.13260-0.602905.337903.99890K562TIAL1
FBXO22ENSG00000167196.9761.277401113.34650-0.548405.492604.05130K562TRIM56
FBXO22ENSG00000167196.92736.237503378.20830-0.304103.136201.63800K562UBE2L3
FBXO22ENSG00000167196.91234.308201651.84770-0.420406.772005.70310K562UPF1
FBXO22ENSG00000167196.92202.463302658.28650-0.271402.253301.48720K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for FBXO22 is not available on ENCORE database.





18 RBPs can affect the splicing of FBXO22 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEFBXO22ENSG00000167196.9chr15+761968317619697076196199761964447620554376205631-0.322000.000270.00717excludedK562SF3B4
SEFBXO22ENSG00000167196.9chr15+762095707620973576206450762065467622222476222390-0.124000.000000.00000excludedK562SF3B4
SEFBXO22ENSG00000167196.9chr15+761968317619697076196199761964447620554376205631-0.135000.000860.05374excludedHepG2RBM22
SEFBXO22ENSG00000167196.9chr15+762222247622239076209570762097357622502576227609-0.066000.001060.02156excludedHepG2U2AF1
SEFBXO22ENSG00000167196.9chr15+761968317619697076196199761964447620554376205631-0.212000.000000.00002excludedHepG2U2AF1
SEFBXO22ENSG00000167196.9chr15+761968317619697076196322761964447620554376205631-0.217000.000050.05151excludedHepG2TROVE2
SEFBXO22ENSG00000167196.9chr15+761968317619697076196216761964447620554376205631-0.276000.000000.00011excludedHepG2HNRNPK
SEFBXO22ENSG00000167196.9chr15+761968317619697076196322761964447620554376205631-0.134000.001020.07548excludedHepG2TBRG4
SEFBXO22ENSG00000167196.9chr15+762222247622239076209570762097357622502576227609-0.095000.000000.00000excludedHepG2U2AF2
SEFBXO22ENSG00000167196.9chr15+761968317619697076196199761964447620554376205631-0.155000.000060.00124excludedHepG2U2AF2
SEFBXO22ENSG00000167196.9chr15+762095707620973576206450762065467622222476222390-0.074000.000010.00012excludedK562AQR
SEFBXO22ENSG00000167196.9chr15+761968317619697076196199761964447620554376205631-0.080000.000050.01536excludedK562DROSHA
SEFBXO22ENSG00000167196.9chr15+761968317619697076196199761964447620554376205631-0.202000.000070.00544excludedHepG2MATR3
SEFBXO22ENSG00000167196.9chr15+7619683176197007761962987619644476205543762056310.360000.000920.06150includedHepG2HNRNPL
SEFBXO22ENSG00000167196.9chr15+761968317619697076196322761964447620554376205631-0.153000.003380.06543excludedHepG2SRSF1
SEFBXO22ENSG00000167196.9chr15+761968317619697076196199761964447620554376205631-0.122000.000710.02338excludedHepG2SF3A3
SEFBXO22ENSG00000167196.9chr15+762095887620973576206450762065467622222476222996-0.065000.003600.08214excludedHepG2SF3A3
SEFBXO22ENSG00000167196.9chr15+761968317619697076196199761964447620554376205631-0.215000.000050.00690excludedHepG2TIAL1
SEFBXO22ENSG00000167196.9chr15+7619683176196970761961997619644476205543762056310.131000.001070.05056includedHepG2PCBP1
SEFBXO22ENSG00000167196.9chr15+761968317619697076196322761964447620554376205631-0.244000.002710.04464excludedK562U2AF2
SEFBXO22ENSG00000167196.9chr15+762096897620973576206450762065467622222476223188-0.075000.001000.02731excludedK562RBM15
A3SSFBXO22ENSG00000167196.9chr15+762095707620973176209689762097317620645076206546-0.082000.001210.09136shorterK562SRSF1
MXEFBXO22ENSG00000167196.9chr15+76209570762097357622222476222390761968317619697076225025762276090.080000.002890.048191includedHepG2U2AF1
MXEFBXO22ENSG00000167196.9chr15+7619683176196970762055437620563176196218761964447620957076209735-0.149000.000000.000012includedK562DROSHA
MXEFBXO22ENSG00000167196.9chr15+7619683176196970762055437620563176196218761964447622222476222390-0.088000.005260.071952includedK562PUS1
MXEFBXO22ENSG00000167196.9chr15+76209689762097317622222476222390762064507620654676225025762251390.060000.006040.076251includedK562SRSF1
MXEFBXO22ENSG00000167196.9chr15+76196732761969707620554376205631761962187619644476222224762223900.229000.003900.029181includedK562AQR
MXEFBXO22ENSG00000167196.9chr15+7620957076209731762222247622243676206450762065467622502576225139-0.073000.000000.000062includedK562AQR
MXEFBXO22ENSG00000167196.9chr15+7620957076209731762222247622239076206450762065467622502576225139-0.130000.000410.004192includedK562AQR
MXEFBXO22ENSG00000167196.9chr15+76196831761969707620554376205631761962187619644476222224762223900.253000.001990.045911includedK562TARDBP
MXEFBXO22ENSG00000167196.9chr15+76196831761969707620554376205631761962187619644476209570762097350.261000.002860.059071includedK562TARDBP
MXEFBXO22ENSG00000167196.9chr15+76209570762097357622222476222390761968317619697076225025762276090.164000.000000.000001includedHepG2U2AF2

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for FBXO22 is not avaliable on ENCORE database.