EIF4E2

General Information

Gene Name       : EIF4E2
Gene ID             : ENSG00000135930.13
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: EIF4E2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878EIF4E2ENSG00000135930.1373.0982.1877.64ENCSR000AEF
HepG2EIF4E2ENSG00000135930.1395.4195.7795.59ENCSR985KAT
K562EIF4E2ENSG00000135930.1361.7359.9460.83ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for EIF4E2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • EIF4E2 RNA is bound by 12 proteins.  







eCLIP assay for EIF4E2 is not avaliable on ENCORE database.





12 proteins are bound to EIF4E2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr2233433785233433834+3'-UTR,intron-Distal3.957764.01763HepG2GRWD1
chr2233447439233447527+3'-UTR3.414923.93348K562TARDBP
chr2233445600233445658+3'-UTR,CDS,intron-Proximal3.935098.23042HepG2U2AF2
chr2233415470233415580+5'-UTR,intron-Distal,intron-Proximal3.694936.60364HepG2RBM22
chr2233421133233421241+CDS,intron-Proximal3.645273.62913HepG2TRA2A
chr2233431865233431925+CDS,intron-Proximal3.713393.01531K562YBX3
chr2233431609233431692+CDS,intron-Proximal3.943305.10069HepG2GRWD1
chr2233431550233431623+CDS3.475843.61259K562ZNF622
chr2233421186233421242+CDS,intron-Proximal5.8608114.66071K562UCHL5
chr2233422591233422634+CDS,intron-Distal,intron-Proximal3.359854.92880K562ZNF622
chr2233421184233421241+CDS,intron-Proximal3.143115.00109HepG2GRWD1
chr2233421182233421242+CDS,intron-Proximal3.7381710.17809K562ZNF622
chr2233428975233429045+CDS3.764104.45064HepG2GRWD1
chr2233422592233422635+CDS,intron-Distal,intron-Proximal3.336907.66871HepG2BCLAF1
chr2233421188233421242+CDS,intron-Proximal5.534649.10017HepG2BCLAF1
chr2233422634233422704+CDS,intron-Distal3.580953.38948K562ZNF800
chr2233421123233421182+CDS,intron-Proximal3.071407.04499HepG2GRWD1
chr2233421187233421240+CDS4.033746.81948K562ZNF800
chr2233431797233431863+CDS3.366324.65365HepG2GRWD1
chr2233421190233421243+CDS,intron-Proximal3.068824.41403K562GRWD1
chr2233431658233431760+CDS,intron-Proximal3.840876.82513HepG2PRPF8
chr2233422592233422639+CDS,intron-Distal,intron-Proximal3.608198.10543K562UCHL5
chr2233422593233422634+CDS,intron-Distal,intron-Proximal4.632704.66217K562ZNF800
chr2233421124233421186+CDS,intron-Proximal3.514567.85262K562UCHL5
chr2233422592233422640+CDS,intron-Distal,intron-Proximal5.334788.08487HepG2GRWD1
chr2233444748233444833+intron-Distal3.6682411.73325HepG2HNRNPL
chr2233443788233443900+intron-Distal3.729855.78457HepG2HNRNPL
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for EIF4E2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for EIF4E2 is not available on ENCORE database.

  • 118 RBPs can affect the levels of EIF4E2.  








The Knockdown/knockout RNA-Seq assay for EIF4E2 is not available on ENCORE database.





118 RBPs can affect the gene expression of EIF4E2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
EIF4E2ENSG00000135930.91290.019701036.729000.315302.301901.32190HepG2AATF
EIF4E2ENSG00000135930.91538.639801254.666200.294303.804103.11260HepG2ACO1
EIF4E2ENSG00000135930.91558.561801114.666500.483504.553803.31470HepG2ADAR
EIF4E2ENSG00000135930.93234.613001377.850201.2311021.2815019.95210HepG2AKAP1
EIF4E2ENSG00000135930.91647.090901264.658200.381102.549601.54940HepG2AKAP8
EIF4E2ENSG00000135930.91665.206801260.636900.401406.083004.98630HepG2AKAP8L
EIF4E2ENSG00000135930.92330.836101140.090201.0316017.5474015.76500HepG2ASCC1
EIF4E2ENSG00000135930.91319.256501838.94270-0.479208.956207.83750HepG2AUH
EIF4E2ENSG00000135930.91572.733201209.726300.378502.588701.68420HepG2BCCIP
EIF4E2ENSG00000135930.91711.810101424.750700.264701.886301.38410HepG2BOP1
EIF4E2ENSG00000135930.91757.436101372.142000.356903.676702.80490HepG2CALR
EIF4E2ENSG00000135930.92857.903601083.152901.3996033.3954031.18640HepG2CIRBP
EIF4E2ENSG00000135930.91545.984101254.484800.301304.266003.47430HepG2CKAP4
EIF4E2ENSG00000135930.91057.708701308.00430-0.306402.080901.47460HepG2CPSF6
EIF4E2ENSG00000135930.91045.52980747.321600.484304.409603.08590HepG2CSTF2
EIF4E2ENSG00000135930.91489.933901730.16290-0.215701.877101.32890HepG2CELF1
EIF4E2ENSG00000135930.92219.824801860.199000.254904.108903.23410HepG2DAZAP1
EIF4E2ENSG00000135930.91413.639701160.428400.284703.632902.69490HepG2DDX19B
EIF4E2ENSG00000135930.91459.349501144.652400.350303.989302.61750HepG2DDX1
EIF4E2ENSG00000135930.91694.182901144.260600.566106.791405.77670HepG2DDX21
EIF4E2ENSG00000135930.91498.948401119.387200.421104.389303.22800HepG2DDX24
EIF4E2ENSG00000135930.91780.259001112.943300.677606.342404.48170HepG2DDX27
EIF4E2ENSG00000135930.92454.373201319.951000.8948013.2195011.94890HepG2DDX3X
EIF4E2ENSG00000135930.91656.110501189.382400.477503.810702.91820HepG2DDX55
EIF4E2ENSG00000135930.91910.522501288.433700.568206.383304.90750HepG2DDX5
EIF4E2ENSG00000135930.91618.039501133.689200.513104.019303.28610HepG2DDX6
EIF4E2ENSG00000135930.91387.623501082.553400.358103.007801.99010HepG2DHX30
EIF4E2ENSG00000135930.91786.630301090.017700.712808.311707.32260HepG2EIF2S1
EIF4E2ENSG00000135930.91301.09310879.740500.564505.285804.06470HepG2EIF3D
EIF4E2ENSG00000135930.92098.692001204.682100.800709.284708.12120HepG2EIF4A3
EIF4E2ENSG00000135930.92368.644701172.765801.0140011.6406010.27760HepG2EIF4B
EIF4E2ENSG00000135930.91412.139801758.10580-0.316102.302501.55550HepG2EIF4G2
EIF4E2ENSG00000135930.92488.459602111.435900.236902.557401.97560HepG2ETF1
EIF4E2ENSG00000135930.91556.413001226.114100.344003.159102.26970HepG2EWSR1
EIF4E2ENSG00000135930.91433.817601090.250700.395103.645902.35810HepG2FASTKD2
EIF4E2ENSG00000135930.92058.698801634.030300.333202.229001.53410HepG2FIP1L1
EIF4E2ENSG00000135930.91456.58560731.037000.9945018.2569016.31800HepG2FUBP3
EIF4E2ENSG00000135930.91845.648701215.218100.602806.336405.31420HepG2FXR1
EIF4E2ENSG00000135930.91583.260801127.427500.489804.036703.24180HepG2G3BP1
EIF4E2ENSG00000135930.91749.973301196.733100.548105.525104.25300HepG2G3BP2
EIF4E2ENSG00000135930.91411.280201123.483900.328902.273601.35410HepG2GNB2L1
EIF4E2ENSG00000135930.9703.711701048.01020-0.574603.539902.27850HepG2GRSF1
EIF4E2ENSG00000135930.92304.712801406.674200.712204.595802.77190HepG2HLTF
EIF4E2ENSG00000135930.91854.788501133.133300.7108010.727409.58050HepG2HNRNPA1
EIF4E2ENSG00000135930.92266.114901709.649000.406407.123205.74330HepG2HNRNPA2B1
EIF4E2ENSG00000135930.91547.625301141.308500.439303.957703.13670HepG2HNRNPK
EIF4E2ENSG00000135930.92149.321401694.453100.343002.682902.01860HepG2HNRNPL
EIF4E2ENSG00000135930.92037.360001415.004900.525805.422204.57040HepG2HNRNPLL
EIF4E2ENSG00000135930.91035.136001377.00360-0.411702.474201.31630HepG2HSPD1
EIF4E2ENSG00000135930.92641.585301146.053201.2046024.3908022.63770HepG2IGF2BP2
EIF4E2ENSG00000135930.92384.224101075.328801.148606.591005.11330HepG2IGF2BP3
EIF4E2ENSG00000135930.91695.710001278.967000.406807.926806.75370HepG2ILF2
EIF4E2ENSG00000135930.91506.014801152.644200.385702.251601.35980HepG2KHSRP
EIF4E2ENSG00000135930.92025.509701215.641200.736509.032207.86120HepG2MAGOH
EIF4E2ENSG00000135930.91596.662601222.486600.385102.552301.94390HepG2MATR3
EIF4E2ENSG00000135930.91797.594701322.620100.442605.073904.00400HepG2MSI2
EIF4E2ENSG00000135930.91862.089001251.316800.573405.514104.63490HepG2NCBP2
EIF4E2ENSG00000135930.91571.228501138.375800.464804.656602.59730HepG2NUP35
EIF4E2ENSG00000135930.91621.083201034.693500.647703.767902.71800HepG2PABPC1
EIF4E2ENSG00000135930.91644.625001114.534600.561205.389904.39290HepG2PABPC4
EIF4E2ENSG00000135930.91848.350701159.797100.6723015.8750014.61540HepG2PCBP1
EIF4E2ENSG00000135930.91985.681401347.894900.5588011.6046010.17820HepG2PRPF4
EIF4E2ENSG00000135930.91191.21990917.675700.376302.754001.94710HepG2PRPF8
EIF4E2ENSG00000135930.91495.481701180.105300.341604.352303.69970HepG2PTBP1
EIF4E2ENSG00000135930.92320.775201869.271600.312006.171605.35870HepG2PUM1
EIF4E2ENSG00000135930.92223.327801867.875800.251202.455101.82390HepG2PUM2
EIF4E2ENSG00000135930.91526.273501277.972300.256103.036902.39900HepG2PUS1
EIF4E2ENSG00000135930.91930.141901278.150500.594509.959408.87790HepG2QKI
EIF4E2ENSG00000135930.92531.223601340.894300.916507.150806.04520HepG2RAVER1
EIF4E2ENSG00000135930.92149.842401764.752300.284703.188302.64240HepG2RBM22
EIF4E2ENSG00000135930.91714.330701159.978300.563407.421706.36200HepG2RBM25
EIF4E2ENSG00000135930.91575.510201077.754200.547704.503003.14670HepG2RCC2
EIF4E2ENSG00000135930.91934.042501313.370100.5582010.797809.85930HepG2NELFE
EIF4E2ENSG00000135930.91558.327801223.178200.349304.426503.67000HepG2RECQL
EIF4E2ENSG00000135930.91701.680102060.03330-0.275702.005301.41300HepG2RPLP0
EIF4E2ENSG00000135930.91044.75690856.032800.287301.992601.46290HepG2RPS19
EIF4E2ENSG00000135930.91315.63310907.787300.535204.488003.51440HepG2RRP9
EIF4E2ENSG00000135930.91422.82540859.152000.727708.979107.30890HepG2SERBP1
EIF4E2ENSG00000135930.92270.732601577.941100.525004.014503.19660HepG2SF3A3
EIF4E2ENSG00000135930.91780.076401400.584100.345802.768002.06120HepG2SF3B1
EIF4E2ENSG00000135930.91673.937801228.698600.446006.933406.06450HepG2SF3B4
EIF4E2ENSG00000135930.93259.014401993.191900.7093024.7782023.66940HepG2SRFBP1
EIF4E2ENSG00000135930.92793.653901282.472201.1231049.6847048.22800HepG2SRSF1
EIF4E2ENSG00000135930.91533.797601878.93460-0.292803.443702.67910HepG2SRSF7
EIF4E2ENSG00000135930.91351.403301043.339500.373105.126404.41690HepG2SRSF9
EIF4E2ENSG00000135930.92149.194401730.508700.312504.545703.92120HepG2SSB
EIF4E2ENSG00000135930.91605.668501103.498000.541006.952805.50970HepG2SUPT6H
EIF4E2ENSG00000135930.91476.691901184.059200.318502.051901.45660HepG2SUPV3L1
EIF4E2ENSG00000135930.91686.593001152.671800.549008.836807.92620HepG2TAF15
EIF4E2ENSG00000135930.91876.529501379.151000.444204.379203.49440HepG2TARDBP
EIF4E2ENSG00000135930.91217.32940793.662200.617005.631504.28040HepG2TFIP11
EIF4E2ENSG00000135930.92713.750301397.888100.9569017.6724016.02830HepG2U2AF1
EIF4E2ENSG00000135930.92369.996301076.761501.138103.988302.79100HepG2U2AF2
EIF4E2ENSG00000135930.91006.65540699.492600.525104.590803.60930HepG2UCHL5
EIF4E2ENSG00000135930.91729.875201399.392700.305804.274603.43680HepG2UPF1
EIF4E2ENSG00000135930.91462.491501084.360500.431502.530601.57310HepG2UPF2
EIF4E2ENSG00000135930.91837.658201438.378800.353304.867403.51710HepG2UTP18
EIF4E2ENSG00000135930.91904.537201351.058400.495309.667508.65800HepG2UTP3
EIF4E2ENSG00000135930.91656.586201165.575000.507104.886803.93110HepG2XRN2
EIF4E2ENSG00000135930.91924.601601539.063900.322405.689004.97790HepG2ZNF622
EIF4E2ENSG00000135930.91268.88670920.206400.463406.937606.09770K562AGGF1
EIF4E2ENSG00000135930.91369.338401011.213500.437304.401003.09550K562AKAP8
EIF4E2ENSG00000135930.91472.48220957.527700.620808.063206.89170K562AKAP8L
EIF4E2ENSG00000135930.91272.775401004.698400.341103.756902.68030K562ATP5C1
EIF4E2ENSG00000135930.9953.370701166.16910-0.290702.657201.47300K562DDX21
EIF4E2ENSG00000135930.9995.362601473.69220-0.5661010.451409.27740K562DDX47
EIF4E2ENSG00000135930.91262.020701030.297700.292603.079202.14830K562DKC1
EIF4E2ENSG00000135930.9286.76400487.49020-0.765503.737802.54970K562EIF3A
EIF4E2ENSG00000135930.9557.26090714.34780-0.358302.624401.84740K562EIF3G
EIF4E2ENSG00000135930.9723.75670571.448800.340802.648201.52700K562EIF4B
EIF4E2ENSG00000135930.91620.185301180.361200.456804.618203.50140K562FIP1L1
EIF4E2ENSG00000135930.9822.548901152.68390-0.486803.834202.82070K562FMR1
EIF4E2ENSG00000135930.9974.78190659.940900.562607.242506.32660K562FXR1
EIF4E2ENSG00000135930.91019.724201544.32500-0.598807.804606.52290K562GRSF1
EIF4E2ENSG00000135930.9543.54750726.82060-0.419203.010802.39180K562HNRNPC
EIF4E2ENSG00000135930.91210.45790867.563900.480402.620401.42200K562HNRNPK
EIF4E2ENSG00000135930.91554.63010970.918700.679007.126705.52380K562HNRNPM
EIF4E2ENSG00000135930.91906.017301297.625300.554602.808601.37740K562ILF2
EIF4E2ENSG00000135930.9688.09440500.702900.458602.977001.42610K562ILF3
EIF4E2ENSG00000135930.91396.049501016.136700.458205.320304.09840K562KIF1C
EIF4E2ENSG00000135930.9919.91020703.650300.386502.996901.54260K562LARP7
EIF4E2ENSG00000135930.91484.006101138.335300.382503.723202.64170K562MBNL1
EIF4E2ENSG00000135930.9880.112901060.73480-0.269302.552301.77410K562MTPAP
EIF4E2ENSG00000135930.91186.32930797.894100.572103.289002.31130K562NAA15
EIF4E2ENSG00000135930.9857.39960633.725000.436003.788502.33180K562NCBP2
EIF4E2ENSG00000135930.91651.750201340.022500.301602.220601.48820K562PPIG
EIF4E2ENSG00000135930.91157.72630713.850300.697507.911906.63590K562PRPF8
EIF4E2ENSG00000135930.91763.25130949.524200.8929013.8981012.72610K562PUS1
EIF4E2ENSG00000135930.91339.80300925.235000.534007.745006.78290K562RBM15
EIF4E2ENSG00000135930.9913.78500720.305900.343102.796901.46180K562RBM25
EIF4E2ENSG00000135930.9399.71840727.24920-0.863507.173905.84300K562RPS19
EIF4E2ENSG00000135930.91010.50350789.600500.355803.271202.33970K562SF3B4
EIF4E2ENSG00000135930.91216.08900869.412100.484005.231604.26370K562SRSF1
EIF4E2ENSG00000135930.91331.207001104.912600.268702.225401.48760K562SYNCRIP
EIF4E2ENSG00000135930.91143.94060736.132500.635905.758504.06240K562U2AF1
EIF4E2ENSG00000135930.91117.91670760.138100.556407.051705.77840K562U2AF2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for EIF4E2 is not available on ENCORE database.





13 RBPs can affect the splicing of EIF4E2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEEIF4E2ENSG00000135930.9chr2+233422593233422728233421125233421240233428956233429061-0.153000.000000.00007excludedK562SRSF1
SEEIF4E2ENSG00000135930.9chr2+233438972233439051233431787233431924233445613233446042-0.343000.001620.03082excludedK562SRSF1
SEEIF4E2ENSG00000135930.9chr2+233422593233422728233421125233421240233428956233429061-0.184000.000000.00001excludedK562SF3B4
SEEIF4E2ENSG00000135930.9chr2+233422593233422728233421125233421240233428956233429061-0.138000.000480.02120excludedK562PRPF8
SEEIF4E2ENSG00000135930.9chr2+233422593233422728233421125233421240233428956233429061-0.147000.000520.01189excludedHepG2U2AF1
SEEIF4E2ENSG00000135930.9chr2+233438972233439051233431787233431924233445613233448352-0.355000.000010.00038excludedHepG2U2AF1
SEEIF4E2ENSG00000135930.9chr2+2334225932334227282334211252334212402334289562334290610.061000.001370.07289includedHepG2AKAP1
SEEIF4E2ENSG00000135930.9chr2+233422593233422728233421125233421240233428956233429061-0.126000.000000.00009excludedK562AQR
SEEIF4E2ENSG00000135930.9chr2+233422593233422728233421125233421240233428956233429061-0.081000.003200.04403excludedK562PUS1
SEEIF4E2ENSG00000135930.9chr2+2334225932334227282334211252334212402334289562334290610.145000.000320.05340includedK562LARP4
SEEIF4E2ENSG00000135930.9chr2+233422593233422728233421097233421240233428956233429061-0.150000.000020.00109excludedHepG2SF3A3
SEEIF4E2ENSG00000135930.9chr2+2334225932334227282334211252334212402334289562334290610.096000.000540.08132includedK562UPF1
SEEIF4E2ENSG00000135930.9chr2+233422593233422728233421125233421240233428956233429061-0.209000.001010.04032excludedK562SF3B1
SEEIF4E2ENSG00000135930.9chr2+233438972233439051233431787233431924233445613233446042-0.383000.000010.00105excludedHepG2HNRNPU
SEEIF4E2ENSG00000135930.9chr2+233422593233422728233421125233421240233428956233429061-0.112000.000070.00468excludedK562PTBP1
A3SSEIF4E2ENSG00000135930.9chr2+233433654233433920233433761233433920233431787233431924-0.193000.002200.07588shorterHepG2U2AF1
A3SSEIF4E2ENSG00000135930.9chr2+233433654233433920233433761233433920233431787233431924-0.119000.000430.02297shorterK562U2AF1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for EIF4E2 is not avaliable on ENCORE database.