DFFA

General Information

Gene Name       : DFFA
Gene ID             : ENSG00000160049.11
Essential Gene : No

Functions

Localization

Domains (AlphaFold: DFFA)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878DFFAENSG00000160049.1120.0125.4522.73ENCSR000AEF
HepG2DFFAENSG00000160049.1123.0618.3520.70ENCSR985KAT
K562DFFAENSG00000160049.1138.5336.9537.74ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for DFFA is not avaliable on ENCORE database.



Proteins bound to RNA
  • DFFA RNA is bound by 17 proteins.  







eCLIP assay for DFFA is not avaliable on ENCORE database.





17 proteins are bound to DFFA RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr11052004910520101-3'-UTR,intron-Distal3.305583.48322HepG2UPF1
chr11052001110520029-3'-UTR,intron-Distal5.048237.35154K562UPF1
chr11051693010516998-3'-UTR,intron-Distal3.9794810.31199K562UPF1
chr11051781210517855-3'-UTR,intron-Distal4.510189.54560K562UPF1
chr11052037610520421-3'-UTR,intron-Distal4.5679211.05945K562UPF1
chr11051986210519948-3'-UTR,intron-Distal5.2226917.59561K562UPF1
chr11051743910517517-3'-UTR,intron-Distal3.7683815.87170K562AKAP1
chr11052036110520429-3'-UTR,intron-Distal4.155145.40760HepG2UPF1
chr11051835410518416-3'-UTR,intron-Distal3.165827.45155K562UPF1
chr11052034710520376-3'-UTR,intron-Distal4.779769.20161K562UPF1
chr11051998710520066-3'-UTR,intron-Distal6.3643941.51277K562AKAP1
chr11052123310521277-3'-UTR,intron-Distal3.708897.72891K562AKAP1
chr11051964310519728-3'-UTR,intron-Distal3.9358118.79830K562UPF1
chr11052033810520442-3'-UTR,intron-Distal5.0949157.71061K562AKAP1
chr11052054210520580-3'-UTR,intron-Distal3.6368610.05486K562AKAP1
chr11052091010520950-3'-UTR,intron-Distal4.565148.17454K562UPF1
chr11052006610520126-3'-UTR,intron-Distal4.6406625.36645K562AKAP1
chr11052036910520439-3'-UTR,intron-Distal4.159614.05367K562ILF3
chr11052063310520679-3'-UTR,intron-Distal4.1007712.48958K562AKAP1
chr11052310910523178-3'-UTR,CDS,intron-Distal,intron-Proximal3.362374.33455K562LIN28B
chr11051894010519016-3'-UTR,intron-Distal4.3026611.65401K562UPF1
chr11052133310521384-3'-UTR,intron-Distal3.5562817.12464K562UPF1
chr11051986510519985-3'-UTR,intron-Distal5.2773456.11823K562AKAP1
chr11051863210518669-3'-UTR,intron-Distal3.664073.22721K562YBX3
chr11052035610520424-3'-UTR,intron-Distal3.489553.92922HepG2AKAP1
chr11052130910521384-3'-UTR,intron-Distal5.7226319.74642K562AKAP1
chr11051705510517132-3'-UTR,intron-Distal4.403225.31905K562ILF3
chr11052120810521295-3'-UTR,intron-Distal5.1055224.44449HepG2UPF1
chr11051938510519459-3'-UTR,intron-Distal3.016604.90505K562FAM120A
chr11051973110519789-3'-UTR,intron-Distal5.0062031.36685K562UPF1
chr11052129210521333-3'-UTR,intron-Distal3.7055710.76020K562UPF1
chr11051706610517125-3'-UTR,intron-Distal3.661079.87397K562UPF1
chr11051988510519946-3'-UTR,intron-Distal3.079343.63807HepG2UPF1
chr11052089610520968-3'-UTR,intron-Distal5.6062314.67358K562PABPC4
chr11051854510518590-3'-UTR,intron-Distal5.108288.52455K562PABPC4
chr11051807810518144-3'-UTR,intron-Distal3.782126.84486K562LIN28B
chr11052052310520544-3'-UTR,intron-Distal3.445954.44982K562UPF1
chr11051955010519594-3'-UTR,intron-Distal3.276547.59462K562UPF1
chr11051785510517895-3'-UTR,intron-Distal3.693245.95678K562UPF1
chr11053237910532557-5'-UTR,CDS,intron-Distal,intron-Proximal5.1340325.81588K562DDX3X
chr11053239410532550-5'-UTR,CDS,intron-Distal,intron-Proximal3.031183.17744HepG2GRWD1
chr11053244210532571-5'-UTR,CDS,intron-Distal,intron-Proximal3.063144.88807HepG2NCBP2
chr11052919810529249-CDS,intron-Distal,intron-Proximal4.684884.58968K562PRPF8
chr11053239610532412-CDS,intron-Distal4.2235114.49430K562YBX3
chr11052348710523561-CDS,intron-Distal,intron-Proximal3.313733.32039HepG2PPIG
chr11052724010527351-CDS,intron-Distal,intron-Proximal4.054083.60441HepG2GRWD1
chr11052727110527402-CDS,intron-Distal,intron-Proximal3.287863.55800HepG2BCLAF1
chr11052157610521664-CDS,intron-Distal,intron-Proximal3.293863.93112K562RBM15
chr11053237810532396-CDS,intron-Distal3.8056914.23945K562YBX3
chr11052931710529376-CDS,intron-Distal3.4464320.37482K562YBX3
chr11052937610529392-CDS,intron-Distal3.4578713.27793K562YBX3
chr11052931310529421-CDS,intron-Distal,intron-Proximal3.203683.65452K562BUD13
chr11053244010532471-CDS,intron-Distal4.013618.57807K562YBX3
chr11053241210532440-CDS,intron-Distal4.8093315.81003K562YBX3
chr11052737010527450-CDS,intron-Distal,intron-Proximal3.668716.71722K562SF3B4
chr11052344310523498-CDS,intron-Distal,intron-Proximal3.784594.52312K562AQR
chr11052939210529395-CDS,intron-Distal4.4824410.96719K562YBX3
chr11052910010529171-intron-Distal,intron-Proximal4.223463.85435K562PRPF8
chr11053232610532380-intron-Distal4.549858.69247K562AQR
chr11053209410532168-intron-Distal3.821833.33062K562ILF3
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for DFFA is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for DFFA is not available on ENCORE database.

  • 115 RBPs can affect the levels of DFFA.  








The Knockdown/knockout RNA-Seq assay for DFFA is not available on ENCORE database.





115 RBPs can affect the gene expression of DFFA :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
DFFAENSG00000160049.71231.51080967.860600.347504.469403.73290HepG2ACO1
DFFAENSG00000160049.71953.154501502.607800.378202.490201.98320HepG2AKAP1
DFFAENSG00000160049.71141.432001512.97630-0.406505.939604.99530HepG2AUH
DFFAENSG00000160049.7552.78860871.60150-0.656904.828203.67040HepG2BCLAF1
DFFAENSG00000160049.7763.23370967.66110-0.342403.996403.22500HepG2CKAP4
DFFAENSG00000160049.7774.482401282.09940-0.727208.695107.53470HepG2CPSF6
DFFAENSG00000160049.71458.413801170.320700.317403.437702.73830HepG2CELF1
DFFAENSG00000160049.7747.27650929.69760-0.315102.658501.52530HepG2DDX1
DFFAENSG00000160049.7509.89080922.77240-0.855806.688204.77310HepG2DDX27
DFFAENSG00000160049.71073.614201439.49320-0.423102.808702.17870HepG2DDX3X
DFFAENSG00000160049.7586.237501455.92090-1.3124012.1656010.20840HepG2DDX59
DFFAENSG00000160049.7638.12170879.25660-0.462503.918202.76360HepG2DHX30
DFFAENSG00000160049.7692.32910911.63220-0.397004.007303.17500HepG2DNAJC21
DFFAENSG00000160049.7606.518501188.73780-0.970809.616108.55150HepG2EIF2S1
DFFAENSG00000160049.7611.967801189.27700-0.9586014.4138012.66310HepG2EIF4G2
DFFAENSG00000160049.71330.732701737.11990-0.384505.498904.70050HepG2ETF1
DFFAENSG00000160049.7900.667001229.52720-0.449001.956201.39280HepG2G3BP1
DFFAENSG00000160049.7718.46200920.36530-0.357302.557701.93380HepG2HNRNPA1
DFFAENSG00000160049.7790.959301244.55140-0.654006.384305.35370HepG2HNRNPK
DFFAENSG00000160049.7644.136401386.94720-1.1065017.7865016.39280HepG2HNRNPLL
DFFAENSG00000160049.7826.704601016.95230-0.298802.958902.33400HepG2HNRNPU
DFFAENSG00000160049.7617.278401249.85700-1.017809.002707.86330HepG2IGF2BP2
DFFAENSG00000160049.7878.013601096.01640-0.320002.332601.58640HepG2MSI2
DFFAENSG00000160049.71037.084901414.55790-0.447802.377601.48690HepG2MTPAP
DFFAENSG00000160049.7605.51990789.65890-0.383102.717001.31500HepG2NIP7
DFFAENSG00000160049.71833.867801247.901700.555308.711407.38280HepG2NOL12
DFFAENSG00000160049.7773.138901229.81130-0.669607.543906.35010HepG2NSUN2
DFFAENSG00000160049.7442.39800685.48180-0.631803.142102.19340HepG2PABPC1
DFFAENSG00000160049.71021.255601228.63450-0.266702.679902.08070HepG2PCBP1
DFFAENSG00000160049.7736.28900907.04320-0.300902.535801.82690HepG2PPIL4
DFFAENSG00000160049.71030.399201250.14250-0.278903.004802.43880HepG2PTBP1
DFFAENSG00000160049.7655.949901191.20390-0.8608013.3964012.21670HepG2PUF60
DFFAENSG00000160049.71518.433801263.579800.265002.113101.52290HepG2PUM2
DFFAENSG00000160049.7758.37490985.83030-0.378404.513603.76390HepG2PUS1
DFFAENSG00000160049.7895.235201354.01840-0.596908.977607.94940HepG2QKI
DFFAENSG00000160049.7693.065701015.05860-0.550502.568501.88840HepG2RAVER1
DFFAENSG00000160049.71818.000701472.670700.303802.929802.04850HepG2RBM15
DFFAENSG00000160049.71945.010101451.906500.421705.976505.28730HepG2RBM22
DFFAENSG00000160049.7989.953701228.82730-0.311802.545201.89540HepG2RBM25
DFFAENSG00000160049.71189.285301391.32100-0.226402.129201.64240HepG2NELFE
DFFAENSG00000160049.71110.510001295.76760-0.222602.067101.52420HepG2RECQL
DFFAENSG00000160049.72176.983901688.118800.366803.593902.83290HepG2RPLP0
DFFAENSG00000160049.7622.38270997.22430-0.680104.431403.24200HepG2RPS10
DFFAENSG00000160049.7845.88690685.837800.302502.081001.54110HepG2RPS19
DFFAENSG00000160049.7483.13470752.76850-0.639804.203903.25660HepG2RRP9
DFFAENSG00000160049.7752.73130905.65100-0.266802.427701.81780HepG2SAFB2
DFFAENSG00000160049.7920.621201185.44620-0.364801.957101.38770HepG2SF3A3
DFFAENSG00000160049.7832.719601372.79000-0.721209.262008.04610HepG2SF3B1
DFFAENSG00000160049.7941.370801142.11290-0.278903.184102.43970HepG2SLBP
DFFAENSG00000160049.73761.464301527.474601.3000010.643309.11810HepG2SNRNP70
DFFAENSG00000160049.71128.142401477.16590-0.388902.340201.42930HepG2SRSF3
DFFAENSG00000160049.7991.067101176.10190-0.247002.342001.76020HepG2SRSF5
DFFAENSG00000160049.7898.132101423.77980-0.6647014.2111013.22980HepG2SSB
DFFAENSG00000160049.7726.81440981.70680-0.433702.228801.61290HepG2SUPV3L1
DFFAENSG00000160049.7993.090501351.90720-0.445004.010203.15710HepG2TARDBP
DFFAENSG00000160049.7700.39000988.22280-0.496705.367104.71710HepG2TIAL1
DFFAENSG00000160049.7853.19040996.98850-0.224701.929001.44170HepG2TRIM56
DFFAENSG00000160049.7773.214301158.40750-0.583205.399504.53740HepG2U2AF1
DFFAENSG00000160049.7425.97710579.97860-0.445202.407501.69840HepG2UCHL5
DFFAENSG00000160049.7871.080601051.30690-0.271302.742602.04590HepG2UPF1
DFFAENSG00000160049.71384.241501014.999500.447507.020206.13980HepG2UTP3
DFFAENSG00000160049.7678.50340966.38030-0.510203.059202.29770HepG2XRN2
DFFAENSG00000160049.71306.053801978.78180-0.5994010.678909.65900K562AGGF1
DFFAENSG00000160049.71490.238602174.19040-0.544907.199805.42690K562AKAP8
DFFAENSG00000160049.71377.041402058.96500-0.580307.862806.70820K562AKAP8L
DFFAENSG00000160049.72076.085003420.52820-0.7204012.2183011.11190K562AQR
DFFAENSG00000160049.71871.730402321.19650-0.310502.371001.56900K562BOP1
DFFAENSG00000160049.72046.755602468.08930-0.270102.509101.76040K562CPSF6
DFFAENSG00000160049.71546.926402073.42470-0.422607.162405.02790K562DDX27
DFFAENSG00000160049.76094.314004129.558500.5614016.1730014.71680K562DDX47
DFFAENSG00000160049.71514.341302318.18970-0.614305.181703.39380K562EEF2
DFFAENSG00000160049.71084.620602239.97490-1.0463019.5549016.84590K562EFTUD2
DFFAENSG00000160049.71934.510702913.26960-0.5907013.4275012.02680K562EIF2S2
DFFAENSG00000160049.72988.481101461.440301.0319010.181008.23010K562EIF3A
DFFAENSG00000160049.71702.616802398.58500-0.494403.899802.64610K562EIF3D
DFFAENSG00000160049.72125.267901508.935900.494002.518401.75900K562EIF3G
DFFAENSG00000160049.73808.692004576.43790-0.264903.379802.34430K562EIF4G2
DFFAENSG00000160049.7976.360701323.32980-0.438705.369303.45620K562EWSR1
DFFAENSG00000160049.72141.821303151.12370-0.557007.549606.08090K562FIP1L1
DFFAENSG00000160049.72081.440502511.23880-0.270802.093101.34390K562FMR1
DFFAENSG00000160049.71713.967802128.50850-0.312502.186701.37840K562FTO
DFFAENSG00000160049.72451.070301576.643200.6365014.2841013.01630K562FXR1
DFFAENSG00000160049.72117.672302968.27700-0.487108.987007.02090K562GLRX3
DFFAENSG00000160049.71601.052602356.41110-0.557607.462306.15500K562GPKOW
DFFAENSG00000160049.72811.122203882.39280-0.465806.395705.23880K562GRSF1
DFFAENSG00000160049.71051.740002326.00530-1.145105.546603.58720K562HNRNPA2B1
DFFAENSG00000160049.71629.508102317.87370-0.508406.886905.98420K562HNRNPC
DFFAENSG00000160049.72217.947703088.06920-0.477508.543106.98590K562HNRNPU
DFFAENSG00000160049.71183.544301824.06520-0.624005.849804.11950K562IGF2BP2
DFFAENSG00000160049.71060.402101501.06770-0.501404.510802.59570K562ILF3
DFFAENSG00000160049.71449.281902185.24170-0.592508.591806.93040K562KIF1C
DFFAENSG00000160049.71555.847202012.09910-0.371002.119101.31390K562KRR1
DFFAENSG00000160049.71731.469802245.23830-0.374903.674902.01940K562LARP7
DFFAENSG00000160049.72573.199801917.131600.424505.008303.86960K562MAGOH
DFFAENSG00000160049.71496.716802091.68000-0.482905.993004.18810K562MAK16
DFFAENSG00000160049.73733.681804878.08510-0.385703.886902.55270K562MSI2
DFFAENSG00000160049.72585.643903120.71870-0.271403.838802.89980K562MTPAP
DFFAENSG00000160049.71076.831501715.85590-0.672105.896004.43250K562NAA15
DFFAENSG00000160049.72853.609303467.60890-0.281204.180203.28420K562NSUN2
DFFAENSG00000160049.7678.190602035.74610-1.585807.870705.89960K562PABPN1
DFFAENSG00000160049.72638.680303393.53920-0.363002.903302.05060K562PCBP3
DFFAENSG00000160049.71681.281202263.13890-0.428804.245102.42010K562PHF6
DFFAENSG00000160049.72309.699703055.68350-0.403803.455001.68460K562PKM
DFFAENSG00000160049.72138.515802602.89640-0.283502.769801.96680K562POLR2G
DFFAENSG00000160049.72975.441903576.99130-0.265602.114401.40100K562PPIG
DFFAENSG00000160049.71377.901702421.40610-0.813403.158101.55960K562PPP1R8
DFFAENSG00000160049.71112.380702179.74710-0.9705016.7228014.85560K562PRPF8
DFFAENSG00000160049.71537.981702078.27980-0.434404.941603.68590K562PSIP1
DFFAENSG00000160049.72255.869701862.605100.276302.535201.89590K562PTBP1
DFFAENSG00000160049.73765.570204993.28560-0.407104.494803.46000K562PUF60
DFFAENSG00000160049.71069.421102042.26560-0.9333015.9307014.66850K562PUS1
DFFAENSG00000160049.71192.058201529.98010-0.360103.792801.67590K562QKI
DFFAENSG00000160049.71454.525401989.60060-0.451906.854105.94840K562RBM15
DFFAENSG00000160049.7853.510701297.04400-0.603706.971204.75950K562RBM25
DFFAENSG00000160049.72424.865001879.545500.367403.073101.91410K562NELFE
DFFAENSG00000160049.73362.801702220.499400.598706.554905.28760K562RPS19
DFFAENSG00000160049.72567.632801421.112500.853306.099104.54080K562RPS3
DFFAENSG00000160049.71276.190801865.40150-0.547603.486401.71640K562SERBP1
DFFAENSG00000160049.71106.994201862.40420-0.750502.647201.48200K562SF1
DFFAENSG00000160049.71660.453102241.05540-0.432603.459802.36880K562SF3B1
DFFAENSG00000160049.7795.824802137.82720-1.425607.025504.75450K562SNRNP200
DFFAENSG00000160049.71380.707801797.76680-0.380803.513502.32080K562SRFBP1
DFFAENSG00000160049.72564.580003505.20080-0.450808.745007.18290K562SRPK2
DFFAENSG00000160049.72365.750701825.961600.373504.184703.32290K562SRSF1
DFFAENSG00000160049.71273.082701724.45240-0.437804.230902.88730K562SRSF5
DFFAENSG00000160049.71212.725501556.52800-0.360102.790301.50720K562SSB
DFFAENSG00000160049.71355.510902557.88120-0.916103.064201.53830K562SUPT6H
DFFAENSG00000160049.71443.890302110.79100-0.547805.022103.61880K562SUPV3L1
DFFAENSG00000160049.71431.223601848.01900-0.368703.024902.28470K562TARDBP
DFFAENSG00000160049.71261.436501782.61600-0.498906.414705.09180K562TIA1
DFFAENSG00000160049.71423.152701998.92060-0.490104.540803.31690K562TIAL1
DFFAENSG00000160049.71240.913301749.21300-0.495305.295003.67950K562TRA2A
DFFAENSG00000160049.71669.503002123.93410-0.347303.156802.13220K562TRIM56
DFFAENSG00000160049.72998.830603928.99670-0.389808.573306.31100K562TROVE2
DFFAENSG00000160049.71001.397501325.55050-0.404602.687501.61340K562U2AF1
DFFAENSG00000160049.7871.423801368.71430-0.651409.855008.33760K562U2AF2
DFFAENSG00000160049.71486.964502233.84990-0.587206.586204.94100K562UCHL5
DFFAENSG00000160049.72050.567103676.76260-0.8424024.3329022.45930K562UPF1
DFFAENSG00000160049.72685.497903372.48230-0.328602.506501.36750K562UTP3
DFFAENSG00000160049.72358.089403146.11670-0.416005.355104.11590K562WDR3
DFFAENSG00000160049.71424.938202516.64190-0.820603.151601.42600K562YTHDC2
DFFAENSG00000160049.72355.294103853.55990-0.7103012.7567010.75660K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for DFFA is not available on ENCORE database.





4 RBPs can affect the splicing of DFFA :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEDFFAENSG00000160049.7chr1-105234871052367710522524105232661052724610527389-0.055000.000000.00306excludedK562APOBEC3C
SEDFFAENSG00000160049.7chr1-105234871052367710522524105232661052724610527389-0.088000.000310.01211excludedHepG2SF3A3
MXEDFFAENSG00000160049.7chr1-10527246105273891052923310529395105234871052367710532379105325830.188000.000040.003051includedK562UCHL5
MXEDFFAENSG00000160049.7chr1-10527246105273891052923310529395105234871052367710532379105325830.137000.006460.096481includedHepG2DDX55

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for DFFA is not avaliable on ENCORE database.