TXN

General Information

Gene Name       : TXN
Gene ID             : ENSG00000136810.12
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: TXN)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878TXNENSG00000136810.12428.17405.36416.76ENCSR000AEF
HepG2TXNENSG00000136810.12320.76421.69371.23ENCSR985KAT
K562TXNENSG00000136810.12321.91355.06338.49ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for TXN is not avaliable on ENCORE database.



Proteins bound to RNA
  • TXN RNA is bound by 24 proteins.  







eCLIP assay for TXN is not avaliable on ENCORE database.





24 proteins are bound to TXN RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr9113006392113006431-3'-UTR,intron-Distal3.8402711.03016HepG2LARP4
chr9113006315113006366-3'-UTR,intron-Distal3.7650516.36991HepG2LARP4
chr9113006318113006364-3'-UTR,intron-Distal3.330407.45099K562APOBEC3C
chr9113006313113006365-3'-UTR,intron-Distal4.93144400.00000K562PABPC4
chr9113018715113018748-5'-UTR,intron-Distal,intron-Proximal3.1157622.86258K562YBX3
chr9113018706113018826-5'-UTR,CDS,intron-Distal,intron-Proximal3.813114.87311K562EIF3G
chr9113018822113018889-5'-UTR,intron-Distal,intron-Proximal5.2355310.32964HepG2DDX3X
chr9113018722113018792-5'-UTR,intron-Distal,intron-Proximal3.494677.73390K562DROSHA
chr9113018693113018779-5'-UTR,CDS,intron-Distal,intron-Proximal3.57718400.00000K562DDX3X
chr9113018716113018786-5'-UTR,intron-Distal,intron-Proximal3.3637720.90392K562GEMIN5
chr9113018770113018815-5'-UTR,intron-Distal,intron-Proximal4.317104.94898K562NOLC1
chr9113018779113018823-5'-UTR,intron-Distal,intron-Proximal3.9150553.00250K562DDX3X
chr9113018823113018867-5'-UTR,intron-Distal,intron-Proximal4.5598623.28468K562DDX3X
chr9113018702113018813-5'-UTR,CDS,intron-Distal,intron-Proximal4.1875811.98970HepG2DDX3X
chr9113018692113018788-5'-UTR,CDS,intron-Distal,intron-Proximal3.3796615.01559HepG2EIF3D
chr9113007057113007064-CDS,intron-Distal,intron-Proximal5.446559.96049HepG2LARP4
chr9113006474113006492-CDS,intron-Distal3.8832211.49033HepG2LARP4
chr9113013099113013156-CDS,intron-Distal,intron-Proximal4.8623715.83575K562LIN28B
chr9113013653113013689-CDS,intron-Distal3.681275.44438HepG2DDX3X
chr9113006492113006499-CDS,intron-Distal4.6288110.31962HepG2LARP4
chr9113013659113013730-CDS,intron-Distal4.1433814.58331HepG2RPS3
chr9113018652113018695-CDS,intron-Distal3.355934.20336HepG2AQR
chr9113007081113007123-CDS,intron-Distal5.6514111.88808K562LIN28B
chr9113013658113013719-CDS,intron-Distal4.0853015.66647K562RPS3
chr9113013602113013662-CDS,intron-Distal,intron-Proximal4.049094.16174HepG2PRPF8
chr9113006492113006499-CDS,intron-Distal3.105115.29764K562SND1
chr9113013660113013709-CDS,intron-Distal3.7600510.11126HepG2LARP4
chr9113013099113013159-CDS,intron-Distal,intron-Proximal3.218575.66692K562SND1
chr9113007064113007074-CDS,intron-Distal4.430708.88091HepG2LARP4
chr9113006456113006500-CDS,intron-Distal3.963895.17497K562APOBEC3C
chr9113016199113016310-intron-Distal3.777123.39667K562HNRNPL
chr9113013010113013051-intron-Distal,intron-Proximal4.997354.24111K562EFTUD2
chr9113018343113018405-intron-Distal3.030803.17659HepG2RBFOX2
chr9113018561113018625-intron-Distal3.652383.41960K562GTF2F1
chr9113018510113018625-intron-Distal4.3241515.12503HepG2CSTF2T
chr9113018561113018623-intron-Distal3.475234.14347HepG2XRN2
chr9113007737113007832-intron-Distal3.005933.20171HepG2ILF3
chr9113018127113018224-intron-Distal3.620375.12237K562CSTF2T
chr9113018410113018495-intron-Distal3.198817.16911K562CSTF2T
chr9113018382113018486-intron-Distal3.732367.91517HepG2EFTUD2
chr9113018556113018615-intron-Distal3.470654.10368K562AKAP8L
chr9113018517113018552-intron-Distal3.078543.51554HepG2PRPF4
chr9113018645113018675-intron-Distal3.378235.34140HepG2PRPF8
chr9113018512113018612-intron-Distal4.3456211.59516HepG2EFTUD2
chr9113018420113018489-intron-Distal3.244153.91530HepG2PRPF4
chr9113018539113018624-intron-Distal3.981386.34048K562CSTF2T
chr9113018552113018629-intron-Distal3.901908.11150HepG2PRPF4
chr9113018522113018619-intron-Distal3.890266.37789HepG2GTF2F1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for TXN is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for TXN is not available on ENCORE database.

  • 114 RBPs can affect the levels of TXN.  








The Knockdown/knockout RNA-Seq assay for TXN is not available on ENCORE database.





114 RBPs can affect the gene expression of TXN :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
TXNENSG00000136810.82507.483203676.86190-0.552205.104804.40930HepG2AKAP1
TXNENSG00000136810.82921.582903740.78850-0.356606.800205.79950HepG2AUH
TXNENSG00000136810.83193.936402361.706300.435406.063404.97670HepG2CALR
TXNENSG00000136810.82561.666101962.508400.384308.477807.43730HepG2CKAP4
TXNENSG00000136810.8903.187402037.24480-1.1735012.2636010.69520HepG2CNOT7
TXNENSG00000136810.81573.817202175.21730-0.466904.666403.79420HepG2CPSF6
TXNENSG00000136810.81998.626301615.442300.307002.468701.44900HepG2CSTF2
TXNENSG00000136810.83284.335203875.48050-0.238804.295903.40550HepG2DAZAP1
TXNENSG00000136810.82072.038301815.532400.190602.263301.50410HepG2DDX19B
TXNENSG00000136810.81697.047502094.42140-0.303503.597002.27790HepG2DDX1
TXNENSG00000136810.82313.207703522.24680-0.606606.952906.00340HepG2DDX3X
TXNENSG00000136810.81332.478601980.78710-0.572007.451705.91330HepG2DHX30
TXNENSG00000136810.81606.619202053.73070-0.354204.778503.87650HepG2DNAJC21
TXNENSG00000136810.81602.238502035.44750-0.345306.424205.48930HepG2DNAJC2
TXNENSG00000136810.82328.893503214.52430-0.465003.815703.07010HepG2EIF4A3
TXNENSG00000136810.82238.325003129.59370-0.483603.270902.52610HepG2EIF4B
TXNENSG00000136810.82487.299703662.59230-0.558305.673604.53000HepG2EIF4G2
TXNENSG00000136810.83015.829004295.00060-0.5101013.4917012.32900HepG2ETF1
TXNENSG00000136810.82747.654301918.157200.518407.407006.04400HepG2EWSR1
TXNENSG00000136810.81167.324901446.05160-0.308902.797401.62200HepG2FAM120A
TXNENSG00000136810.81651.378002140.18830-0.374102.770101.49930HepG2FKBP4
TXNENSG00000136810.81968.060603008.52980-0.612306.523505.52420HepG2G3BP1
TXNENSG00000136810.81767.359301440.690200.294702.071601.30200HepG2GEMIN5
TXNENSG00000136810.81526.998202202.92660-0.528705.148203.75390HepG2GNB2L1
TXNENSG00000136810.81757.066702306.22990-0.392403.966803.14760HepG2HNRNPC
TXNENSG00000136810.81928.792902576.31680-0.417607.654406.54090HepG2HNRNPF
TXNENSG00000136810.82460.523203046.02590-0.308002.525101.85630HepG2HNRNPK
TXNENSG00000136810.81772.178102353.21630-0.409103.578102.87220HepG2HNRNPLL
TXNENSG00000136810.81728.055902290.98610-0.406807.660406.68940HepG2HNRNPU
TXNENSG00000136810.82157.886002536.94120-0.233501.950301.33380HepG2IGF2BP1
TXNENSG00000136810.82272.043003244.13910-0.513805.130704.24570HepG2MAGOH
TXNENSG00000136810.81756.729102399.77580-0.450002.771301.80280HepG2MTPAP
TXNENSG00000136810.82083.214203339.23470-0.680708.156107.09530HepG2NCBP2
TXNENSG00000136810.83316.635203842.92010-0.212502.107501.43950HepG2NOL12
TXNENSG00000136810.82552.420801861.915400.455002.174301.40200HepG2PABPC1
TXNENSG00000136810.81914.425002973.99580-0.635507.328206.16370HepG2PABPC4
TXNENSG00000136810.81860.145602267.74550-0.285803.855102.87380HepG2PARN
TXNENSG00000136810.82061.854703019.96590-0.5506013.8989012.70540HepG2PCBP1
TXNENSG00000136810.8462.228002280.85120-2.3029045.2839041.86490HepG2PCBP2
TXNENSG00000136810.81701.302902043.38510-0.264302.855602.10900HepG2PPIL4
TXNENSG00000136810.81950.353603072.99550-0.6559017.7869016.62810HepG2PTBP1
TXNENSG00000136810.83435.481103894.19080-0.180802.831302.23290HepG2PUM1
TXNENSG00000136810.81830.085403327.98660-0.8627024.3245022.73490HepG2QKI
TXNENSG00000136810.83546.668702201.065900.688204.526703.63670HepG2RAVER1
TXNENSG00000136810.85561.455103589.810100.6315018.0227016.93370HepG2RBM22
TXNENSG00000136810.82828.638703185.26690-0.171301.845701.32800HepG2RECQL
TXNENSG00000136810.81436.164202162.13300-0.590203.934202.80940HepG2RPS10
TXNENSG00000136810.81172.288901574.40590-0.425504.419303.66060HepG2RPS19
TXNENSG00000136810.81591.401402400.22150-0.592907.375706.10820HepG2RPS2
TXNENSG00000136810.81514.341502045.31430-0.433602.697801.90820HepG2RPS3A
TXNENSG00000136810.83561.406402187.519000.703102.996902.29410HepG2SF3A3
TXNENSG00000136810.82658.379303199.26430-0.267203.908603.22600HepG2SF3B4
TXNENSG00000136810.82778.677003517.45480-0.340107.744906.65990HepG2SLBP
TXNENSG00000136810.85557.401204054.530900.4548013.9579013.06300HepG2SRFBP1
TXNENSG00000136810.84104.133303339.388500.297405.556704.94490HepG2SRSF1
TXNENSG00000136810.82594.916303622.03390-0.4811011.6136010.45540HepG2SRSF5
TXNENSG00000136810.81900.590802531.13010-0.413307.546006.48820HepG2SRSF7
TXNENSG00000136810.82343.981701730.386300.437803.426702.01670HepG2SSRP1
TXNENSG00000136810.83117.592004119.24050-0.4019010.721309.63140HepG2SUCLG1
TXNENSG00000136810.82451.024101752.340100.484003.509001.99800HepG2SUGP2
TXNENSG00000136810.81952.529301593.660600.292902.762901.82280HepG2SUPT6H
TXNENSG00000136810.81797.928903001.70920-0.7394019.4555018.16160HepG2TAF15
TXNENSG00000136810.81504.238702293.41590-0.608507.858506.71880HepG2TARDBP
TXNENSG00000136810.82285.512302758.01690-0.271102.546901.74250HepG2TIA1
TXNENSG00000136810.81479.047902246.00910-0.6027015.1074013.93920HepG2TRIM56
TXNENSG00000136810.82590.872303583.89870-0.468106.773705.31290HepG2TUFM
TXNENSG00000136810.82589.946303793.51070-0.550605.732104.49850HepG2UBE2L3
TXNENSG00000136810.82221.592701939.988500.195402.258901.61710HepG2UPF1
TXNENSG00000136810.82497.459601994.085100.324604.695803.36850HepG2UTP18
TXNENSG00000136810.82788.158501872.992500.5739015.2588014.02060HepG2UTP3
TXNENSG00000136810.83373.173002519.695000.420804.062303.19130HepG2XRN2
TXNENSG00000136810.82982.939302133.625100.4833014.6368013.62380HepG2ZNF622
TXNENSG00000136810.85308.202903127.269000.7632031.6347029.80400K562AGGF1
TXNENSG00000136810.84742.663403436.439500.464706.104904.50340K562AKAP8
TXNENSG00000136810.84869.796803254.075900.581509.182107.91120K562AKAP8L
TXNENSG00000136810.83797.317305439.31600-0.518407.111706.24120K562AQR
TXNENSG00000136810.84420.021503414.329200.372406.224504.78680K562ATP5C1
TXNENSG00000136810.82349.431703202.12580-0.446709.988808.14540K562BCLAF1
TXNENSG00000136810.82223.531002984.93830-0.424804.205103.12300K562BOP1
TXNENSG00000136810.81202.843601522.44610-0.339902.449401.46740K562CCAR1
TXNENSG00000136810.84793.906003737.223200.359103.733002.33570K562CCDC124
TXNENSG00000136810.82882.510904261.98760-0.564203.320802.13650K562CNOT7
TXNENSG00000136810.82300.896503173.82920-0.464006.757805.52380K562CPSF6
TXNENSG00000136810.81730.840702429.28880-0.489107.854505.94300K562CSTF2
TXNENSG00000136810.84631.246003501.551600.403304.867603.65390K562DKC1
TXNENSG00000136810.81592.078702337.46810-0.554006.263104.84370K562EFTUD2
TXNENSG00000136810.82912.120103665.79400-0.332105.234604.29050K562EIF2S2
TXNENSG00000136810.81550.264902571.10090-0.7299011.8932010.15680K562EIF4A3
TXNENSG00000136810.81880.164102490.31250-0.405503.107101.76140K562EXOSC5
TXNENSG00000136810.85106.470703369.524300.599709.271607.62080K562FIP1L1
TXNENSG00000136810.82562.681803229.32820-0.333602.948802.06500K562FMR1
TXNENSG00000136810.82046.069802737.16090-0.419803.636002.57550K562FTO
TXNENSG00000136810.83072.348402673.849500.200302.252901.69660K562FXR1
TXNENSG00000136810.82098.562203030.21260-0.530007.265205.97780K562GPKOW
TXNENSG00000136810.82938.135903630.35950-0.305203.245102.08030K562HNRNPA1
TXNENSG00000136810.81377.191203118.45170-1.1791034.2231032.19830K562HNRNPC
TXNENSG00000136810.81836.361802785.26140-0.601009.350307.19730K562HNRNPF
TXNENSG00000136810.84435.374902771.639800.678208.543206.75320K562HNRNPM
TXNENSG00000136810.82991.806604020.44250-0.426307.323705.87240K562HNRNPU
TXNENSG00000136810.85492.456704568.138000.265702.275901.54960K562HSPD1
TXNENSG00000136810.85041.064903453.350300.545608.659106.98880K562KIF1C
TXNENSG00000136810.84403.627503305.736400.413604.772103.24400K562MAK16
TXNENSG00000136810.85368.671203868.629800.472605.784504.38180K562MBNL1
TXNENSG00000136810.82140.602702957.83120-0.466506.006704.68980K562METAP2
TXNENSG00000136810.82687.036003104.06870-0.208102.716901.91500K562MTPAP
TXNENSG00000136810.83602.543902711.632700.409802.825601.93270K562NAA15
TXNENSG00000136810.82487.554203448.85990-0.4714016.6376015.01780K562NSUN2
TXNENSG00000136810.81021.792503276.23290-1.6809058.9207054.54180K562PCBP2
TXNENSG00000136810.84968.718503825.304400.377203.812602.82760K562PPIG
TXNENSG00000136810.82843.903902274.619000.322102.782302.03080K562PRPF8
TXNENSG00000136810.82304.433402796.15220-0.279002.330301.50630K562PSIP1
TXNENSG00000136810.86108.395403227.074100.9205019.5286018.11490K562PUS1
TXNENSG00000136810.85148.671603144.360800.7113020.1194018.47910K562RBM15
TXNENSG00000136810.82682.631203430.48850-0.354803.437702.49520K562RBM22
TXNENSG00000136810.82128.545202551.77000-0.261602.490701.55450K562RCC2
TXNENSG00000136810.82605.833803403.20280-0.385106.618805.40440K562SF3A3
TXNENSG00000136810.82319.482102881.88820-0.313202.151301.30510K562SF3B1
TXNENSG00000136810.82570.200003506.95710-0.448306.274305.22070K562SRSF1
TXNENSG00000136810.81469.308601859.29190-0.339603.204902.05580K562SRSF4
TXNENSG00000136810.82134.277802699.37580-0.338903.938202.52200K562SRSF7
TXNENSG00000136810.81393.905202202.65870-0.660107.070205.39170K562SUPV3L1
TXNENSG00000136810.83045.523202437.028500.321502.562901.77480K562SYNCRIP
TXNENSG00000136810.82593.402403549.37070-0.452704.795803.85410K562TARDBP
TXNENSG00000136810.82614.236803423.74220-0.389204.973503.82580K562TIA1
TXNENSG00000136810.81881.763202689.35270-0.515205.332103.99390K562TIAL1
TXNENSG00000136810.82768.307503359.46950-0.279202.371001.37640K562TRA2A
TXNENSG00000136810.82144.356702857.80740-0.414404.636503.34010K562TRIM56
TXNENSG00000136810.82684.971103656.90230-0.4457010.837709.53210K562UPF1
TXNENSG00000136810.83023.470503853.48680-0.350003.681501.74880K562UPF2
TXNENSG00000136810.82633.312403129.09080-0.248902.214901.43220K562WDR3
TXNENSG00000136810.81782.308402373.42080-0.413203.536502.10830K562XRN2
TXNENSG00000136810.84838.795106127.50820-0.340703.617102.60530K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for TXN is not available on ENCORE database.





10 RBPs can affect the splicing of TXN :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SETXNENSG00000136810.8chr9-1130136371130137601130070571130071231130186911130187460.597000.000010.00027includedHepG2U2AF1
SETXNENSG00000136810.8chr9-1130136371130137301130070571130071231130186911130187460.387000.001920.02445includedHepG2U2AF2
SETXNENSG00000136810.8chr9-113013099113013159113007057113007123113013637113013730-0.062000.000000.00000excludedHepG2U2AF2
SETXNENSG00000136810.8chr9-113013099113013144113007057113007123113013637113013742-0.058000.000000.00000excludedHepG2SF3A3
MXETXNENSG00000136810.8chr9-1130130991130131441130136371130137421130070571130071231130186911130187460.123000.000000.000151includedK562DROSHA
MXETXNENSG00000136810.8chr9-113013099113013144113013637113013742113007057113007123113018691113018746-0.095000.000010.000742includedHepG2XRN2
MXETXNENSG00000136810.8chr9-1130070571130071231130130991130131591130060901130064991130136371130137420.147000.000420.009941includedHepG2HNRNPUL1
MXETXNENSG00000136810.8chr9-1130070571130071231130130991130131591130060901130064991130136371130137420.153000.000600.023961includedK562SBDS
MXETXNENSG00000136810.8chr9-1130070571130071231130130991130131591130060901130064991130136371130137420.180000.000040.003521includedK562PPIL4
MXETXNENSG00000136810.8chr9-113013099113013144113013637113013742113007057113007123113018691113018746-0.053000.002930.060742includedK562PPIL4
MXETXNENSG00000136810.8chr9-113013099113013144113013637113013742113007057113007123113018691113018746-0.094000.000020.001312includedHepG2SUPV3L1
MXETXNENSG00000136810.8chr9-113013099113013144113013637113013742113007057113007123113018691113018746-0.154000.000010.000572includedK562DHX30

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for TXN is not avaliable on ENCORE database.