TMEM104

General Information

Gene Name       : TMEM104
Gene ID             : ENSG00000109066.13
Essential Gene : No

Functions

Localization

Domains (AlphaFold: TMEM104)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878TMEM104ENSG00000109066.130.853.121.99ENCSR000AEF
HepG2TMEM104ENSG00000109066.1311.076.028.54ENCSR985KAT
K562TMEM104ENSG00000109066.135.485.155.32ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for TMEM104 is not avaliable on ENCORE database.



Proteins bound to RNA
  • TMEM104 RNA is bound by 11 proteins.  







eCLIP assay for TMEM104 is not avaliable on ENCORE database.





11 proteins are bound to TMEM104 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr177283379072833869+3'-UTR,intron-Distal5.126526.23478HepG2AKAP1
chr177283317472833285+3'-UTR,intron-Distal4.910416.81621K562UPF1
chr177283380272833837+3'-UTR,intron-Distal4.191533.19668HepG2UPF1
chr177283319972833293+3'-UTR,intron-Distal4.4327316.47225HepG2PCBP2
chr177283420772834279+3'-UTR,intron-Distal4.144974.45619HepG2UPF1
chr177283442272834458+3'-UTR,intron-Distal4.227573.34655HepG2AKAP1
chr177283319872833261+3'-UTR,intron-Distal3.400993.60809HepG2HNRNPK
chr177283299272833079+3'-UTR,intron-Distal3.064243.05993HepG2AKAP1
chr177283355872833630+3'-UTR,intron-Distal,intron-Proximal5.060015.94150HepG2UPF1
chr177283467372834733+3'-UTR,intron-Distal4.691535.14974HepG2UPF1
chr177283396072834046+3'-UTR,intron-Distal5.8824212.32677HepG2UPF1
chr177283339472833494+3'-UTR,intron-Distal,intron-Proximal5.7664011.54506HepG2UPF1
chr177283320372833310+3'-UTR,intron-Distal4.574887.84191HepG2UPF1
chr177283431072834395+3'-UTR,intron-Distal5.287487.78976HepG2AKAP1
chr177283395072834084+3'-UTR,intron-Distal6.0255311.85767HepG2AKAP1
chr177283308372833161+3'-UTR,intron-Distal5.817398.60492HepG2PCBP2
chr177283320572833250+3'-UTR,intron-Distal3.593514.57758HepG2FAM120A
chr177283318872833345+3'-UTR,intron-Distal5.1635212.15068HepG2AKAP1
chr177283310672833176+3'-UTR,intron-Distal4.496504.94157HepG2IGF2BP1
chr177283311372833188+3'-UTR,intron-Distal4.963975.71320HepG2AKAP1
chr177283297372833064+3'-UTR,intron-Distal5.644758.46737HepG2UPF1
chr177277264572772718+5'-UTR,intron-Proximal4.370536.83552HepG2DDX3X
chr177281592572815997+CDS,intron-Proximal3.384413.05161HepG2PPIG
chr177278707772787122+CDS,intron-Proximal4.151573.35169HepG2U2AF2
chr177278174072781791+CDS,intron-Distal,intron-Proximal4.929355.17615K562AQR
chr177278487972784955+CDS,intron-Distal,intron-Proximal4.976196.35567HepG2PRPF8
chr177278485472784922+intron-Distal,intron-Proximal4.9692110.24966K562AQR
chr177282831772828417+intron-Distal5.203498.60492HepG2PCBP2
chr177278643572786505+intron-Proximal4.681374.48002K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for TMEM104 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for TMEM104 is not available on ENCORE database.

  • 126 RBPs can affect the levels of TMEM104.  








The Knockdown/knockout RNA-Seq assay for TMEM104 is not available on ENCORE database.





126 RBPs can affect the gene expression of TMEM104 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
TMEM104ENSG00000109066.91085.31680727.265200.577504.269303.11720HepG2ABCF1
TMEM104ENSG00000109066.9942.47240486.674900.9534021.3823020.04820HepG2ACO1
TMEM104ENSG00000109066.9907.16940407.752101.1536012.7991011.74310HepG2AKAP1
TMEM104ENSG00000109066.9744.79520449.226300.729306.228404.69950HepG2AKAP8
TMEM104ENSG00000109066.9470.98380337.352300.481302.584701.82390HepG2ASCC1
TMEM104ENSG00000109066.9892.22860656.018200.443603.102101.61420HepG2ATP5C1
TMEM104ENSG00000109066.91214.15140618.954700.9719023.3840021.74430HepG2AUH
TMEM104ENSG00000109066.9740.41220445.429800.733002.251801.41120HepG2BCCIP
TMEM104ENSG00000109066.92175.40600922.241501.2380029.3567027.76250HepG2BOP1
TMEM104ENSG00000109066.9720.68120357.077101.013006.244905.14710HepG2CALR
TMEM104ENSG00000109066.9598.50680320.517100.900908.441407.14770HepG2CIRBP
TMEM104ENSG00000109066.9896.56590486.548900.8817018.8490017.45250HepG2CKAP4
TMEM104ENSG00000109066.9660.74550204.210201.6939017.2607015.40860HepG2CNOT7
TMEM104ENSG00000109066.9778.52930351.502601.1471023.9787022.46890HepG2CELF1
TMEM104ENSG00000109066.9677.87550377.844600.8431015.2778013.77710HepG2DAZAP1
TMEM104ENSG00000109066.9482.78580262.888000.876803.562002.24950HepG2DDX1
TMEM104ENSG00000109066.9372.15890239.598400.635204.031703.22680HepG2DDX21
TMEM104ENSG00000109066.91527.14860390.534901.9672045.1682042.92950HepG2DDX3X
TMEM104ENSG00000109066.9950.85200573.307700.729807.950506.32720HepG2DDX5
TMEM104ENSG00000109066.9650.21530335.620700.954002.529001.93710HepG2DDX6
TMEM104ENSG00000109066.9650.77230465.610800.482903.060202.35190HepG2DKC1
TMEM104ENSG00000109066.9410.48580257.769100.671205.835004.84770HepG2DNAJC21
TMEM104ENSG00000109066.9409.26750255.528500.679506.953605.98550HepG2DNAJC2
TMEM104ENSG00000109066.9437.03380263.973900.727204.594603.42980HepG2EEF2
TMEM104ENSG00000109066.9402.99480220.022600.873006.595404.88220HepG2EFTUD2
TMEM104ENSG00000109066.9631.76600322.498300.970009.382808.32920HepG2EIF2S1
TMEM104ENSG00000109066.9351.80000214.264300.715304.068102.98590HepG2EIF3D
TMEM104ENSG00000109066.9884.87350356.329701.3122017.0247015.44830HepG2EIF4A3
TMEM104ENSG00000109066.9696.98460347.068201.005807.670106.55470HepG2EIF4B
TMEM104ENSG00000109066.9463.46850372.859100.313702.205601.44380HepG2EIF4G1
TMEM104ENSG00000109066.91037.21090710.676800.545307.474106.56640HepG2ETF1
TMEM104ENSG00000109066.9775.79370475.550400.706007.999206.59040HepG2EWSR1
TMEM104ENSG00000109066.9194.00460301.93020-0.638103.812302.89810HepG2FUBP3
TMEM104ENSG00000109066.9611.87020359.729800.766206.302205.28410HepG2FXR1
TMEM104ENSG00000109066.9762.83060333.592701.1932014.5653013.09720HepG2G3BP1
TMEM104ENSG00000109066.9392.33690190.767701.040208.994807.42380HepG2GEMIN5
TMEM104ENSG00000109066.9361.41740189.065300.934705.599404.00880HepG2GRSF1
TMEM104ENSG00000109066.9325.14650172.819600.911703.759802.14590HepG2HNRNPA0
TMEM104ENSG00000109066.9465.66930260.239000.839405.824004.93310HepG2HNRNPA1
TMEM104ENSG00000109066.9308.04660168.746200.868205.189503.24270HepG2HNRNPAB
TMEM104ENSG00000109066.9626.21540289.479601.1131013.2879011.87300HepG2HNRNPC
TMEM104ENSG00000109066.9262.01360344.15500-0.393402.052601.46120HepG2HNRNPL
TMEM104ENSG00000109066.9373.30060287.564800.376402.366901.80310HepG2HNRNPU
TMEM104ENSG00000109066.9692.45480489.015700.501702.843901.59330HepG2HSPD1
TMEM104ENSG00000109066.91093.57170339.050801.6894032.3796030.38320HepG2IGF2BP2
TMEM104ENSG00000109066.9685.25470318.341301.106003.166502.11210HepG2IGF2BP3
TMEM104ENSG00000109066.9467.65970293.736000.670807.578806.42830HepG2ILF2
TMEM104ENSG00000109066.9233.28950341.09990-0.548102.425201.49770HepG2KHSRP
TMEM104ENSG00000109066.9808.30130488.687700.725903.339101.96370HepG2KRR1
TMEM104ENSG00000109066.92128.26350623.907801.7702025.2489022.68180HepG2LARP4
TMEM104ENSG00000109066.9963.93700359.856301.4214018.5305016.91390HepG2MAGOH
TMEM104ENSG00000109066.91408.01310361.836501.9602039.8305037.66090HepG2MATR3
TMEM104ENSG00000109066.9475.38600224.230201.084006.292604.75630HepG2METAP2
TMEM104ENSG00000109066.91017.51470594.142000.776109.808508.37650HepG2MSI2
TMEM104ENSG00000109066.9360.16760498.94430-0.470202.896201.65230HepG2NAA15
TMEM104ENSG00000109066.9716.16050370.332300.951409.408508.28160HepG2NCBP2
TMEM104ENSG00000109066.9953.79630463.440101.041209.594907.04100HepG2NKRF
TMEM104ENSG00000109066.9702.41240432.464100.699603.735402.06940HepG2NOLC1
TMEM104ENSG00000109066.9954.46070402.518301.245505.437303.87580HepG2NONO
TMEM104ENSG00000109066.9586.10870812.16260-0.470603.374702.54850HepG2NSUN2
TMEM104ENSG00000109066.9445.35470186.691901.254204.790903.59800HepG2PABPC1
TMEM104ENSG00000109066.9644.44620329.678700.966909.670508.34060HepG2PABPC4
TMEM104ENSG00000109066.9441.50040284.625200.633305.418604.28770HepG2PARN
TMEM104ENSG00000109066.91005.81820345.642901.5409025.1261023.60640HepG2PCBP1
TMEM104ENSG00000109066.9244.65950478.83530-0.9688012.4685011.00310HepG2PRPF4
TMEM104ENSG00000109066.9555.60240337.559600.718802.844802.02430HepG2PRPF8
TMEM104ENSG00000109066.9960.38740351.726201.4491039.3681037.80080HepG2PTBP1
TMEM104ENSG00000109066.9671.82810357.690400.9093011.6136010.50670HepG2PUF60
TMEM104ENSG00000109066.9794.82860379.738901.0655025.8442024.40710HepG2PUM1
TMEM104ENSG00000109066.9622.75450379.439900.714702.870102.18790HepG2PUM2
TMEM104ENSG00000109066.91226.45530495.707001.3068043.3512041.50040HepG2PUS1
TMEM104ENSG00000109066.9512.19130235.237401.122503.415702.63430HepG2RAVER1
TMEM104ENSG00000109066.9522.43880722.55570-0.467804.047603.03360HepG2RBM15
TMEM104ENSG00000109066.9507.50190169.169801.584805.187602.64650HepG2RBM17
TMEM104ENSG00000109066.91122.21180593.987200.9177016.1618015.11980HepG2RBM22
TMEM104ENSG00000109066.9511.12750345.692300.564104.385603.55330HepG2RBM25
TMEM104ENSG00000109066.9646.15130391.419500.723108.648207.78940HepG2NELFE
TMEM104ENSG00000109066.9468.42350231.359201.017603.977602.84680HepG2RPS10
TMEM104ENSG00000109066.9636.94610208.512501.6109020.3862018.95540HepG2RPS19
TMEM104ENSG00000109066.9548.26230252.075701.120903.823102.88670HepG2RPS2
TMEM104ENSG00000109066.9362.27960205.192300.820004.752503.70530HepG2RPS3A
TMEM104ENSG00000109066.9481.04310209.237001.2009012.2667010.35970HepG2SERBP1
TMEM104ENSG00000109066.9369.76840163.342301.178603.425501.87790HepG2SF1
TMEM104ENSG00000109066.91546.10200859.913200.846307.584606.43310HepG2SF3A3
TMEM104ENSG00000109066.9680.07230366.153500.8931013.2878012.14270HepG2SF3B4
TMEM104ENSG00000109066.9572.33860158.667801.850807.252904.71690HepG2SFPQ
TMEM104ENSG00000109066.9647.21780298.623501.1158021.9621020.42150HepG2SMN1
TMEM104ENSG00000109066.9498.66430240.689001.050805.897204.45850HepG2SMNDC1
TMEM104ENSG00000109066.9526.58100146.147301.849108.410105.86870HepG2SNRNP200
TMEM104ENSG00000109066.9373.943601008.84120-1.4318015.5192013.68330HepG2SNRNP70
TMEM104ENSG00000109066.9860.58070670.874200.359203.381002.84440HepG2SRFBP1
TMEM104ENSG00000109066.9705.43430382.200900.8841013.4742012.59970HepG2SRSF1
TMEM104ENSG00000109066.9693.52960975.50330-0.492203.024801.97040HepG2SRSF3
TMEM104ENSG00000109066.9678.96200353.208800.9427014.8214013.53710HepG2SRSF5
TMEM104ENSG00000109066.9879.71140401.660001.1310015.4894014.21050HepG2SUCLG1
TMEM104ENSG00000109066.9755.94340495.703300.608706.222604.84920HepG2SUPT6H
TMEM104ENSG00000109066.91411.50410892.651800.661008.001606.85240HepG2TARDBP
TMEM104ENSG00000109066.9550.94700279.378700.9796012.3851011.45880HepG2TIAL1
TMEM104ENSG00000109066.91081.97780281.923701.9402073.3265071.00700HepG2TRIM56
TMEM104ENSG00000109066.9661.58500349.505100.920506.045204.68760HepG2TUFM
TMEM104ENSG00000109066.9712.39650169.780302.068909.336207.41180HepG2U2AF2
TMEM104ENSG00000109066.91078.65140369.983001.543605.732604.49870HepG2UBE2L3
TMEM104ENSG00000109066.9456.43400257.456300.826004.520403.54880HepG2UCHL5
TMEM104ENSG00000109066.91854.92630762.610701.2822054.5299052.30890HepG2UPF1
TMEM104ENSG00000109066.91202.48420736.271900.7076014.1296012.93620HepG2UTP3
TMEM104ENSG00000109066.9326.68370183.798800.829704.719703.27360HepG2XPO5
TMEM104ENSG00000109066.9534.61430258.850501.046304.743003.37490HepG2XRCC6
TMEM104ENSG00000109066.92150.25840838.726901.3581063.2944061.58450HepG2ZNF622
TMEM104ENSG00000109066.9181.59570394.32180-1.1186012.0564010.96450K562AGGF1
TMEM104ENSG00000109066.9364.67340256.504900.507502.543701.70810K562BOP1
TMEM104ENSG00000109066.9214.77280118.321700.860004.700203.02800K562CIRBP
TMEM104ENSG00000109066.9487.67010329.445900.565802.356601.38980K562CNOT7
TMEM104ENSG00000109066.9534.67890685.08700-0.357602.215901.34400K562CELF1
TMEM104ENSG00000109066.9278.06970191.967200.534503.115901.70310K562DDX27
TMEM104ENSG00000109066.9271.97080164.298700.727003.024801.93420K562DDX3X
TMEM104ENSG00000109066.9391.35630190.541001.038308.294506.63590K562EFTUD2
TMEM104ENSG00000109066.9382.32430203.896400.906904.592103.21940K562EIF3D
TMEM104ENSG00000109066.9157.49410105.496000.578002.166901.45620K562EIF3G
TMEM104ENSG00000109066.9289.01200171.649800.751604.418603.38140K562EIF4A3
TMEM104ENSG00000109066.9351.66370178.508200.978109.143908.11750K562FXR1
TMEM104ENSG00000109066.916.0664063.87000-1.991105.687204.59120K562G3BP2
TMEM104ENSG00000109066.9516.42530260.353500.9880010.202308.66110K562GPKOW
TMEM104ENSG00000109066.9666.19110511.104500.382202.331201.63490K562GRSF1
TMEM104ENSG00000109066.9521.80060196.089801.4119018.6332017.16060K562HNRNPC
TMEM104ENSG00000109066.9284.75810175.116600.701304.080802.66340K562HNRNPF
TMEM104ENSG00000109066.9199.21190110.458100.850703.689202.43930K562IGF2BP2
TMEM104ENSG00000109066.9177.22260112.326500.657803.014101.75520K562IGF2BP3
TMEM104ENSG00000109066.9287.40740435.44380-0.599403.634602.67300K562KIF1C
TMEM104ENSG00000109066.9286.20580189.912100.591603.197001.67800K562LARP7
TMEM104ENSG00000109066.9213.83590116.027000.881905.388504.20200K562MAGOH
TMEM104ENSG00000109066.9189.29640115.782400.709103.478202.42820K562MATR3
TMEM104ENSG00000109066.9346.49140254.142700.447102.205601.42350K562METAP2
TMEM104ENSG00000109066.9573.85540445.160500.366302.883402.05830K562MTPAP
TMEM104ENSG00000109066.9217.68130341.91670-0.651402.980902.05920K562NAA15
TMEM104ENSG00000109066.9393.94380494.62260-0.328302.330901.64010K562NSUN2
TMEM104ENSG00000109066.9181.17530113.444400.675303.099201.66790K562PCBP1
TMEM104ENSG00000109066.9283.73520191.450800.567502.916001.44860K562PHF6
TMEM104ENSG00000109066.9533.24820373.930000.511903.932402.97070K562POLR2G
TMEM104ENSG00000109066.9314.06800185.421300.760203.968703.07150K562PRPF8
TMEM104ENSG00000109066.9282.93300175.817400.686303.649602.59140K562PSIP1
TMEM104ENSG00000109066.9420.52450112.732001.8992030.0488027.95560K562PTBP1
TMEM104ENSG00000109066.9279.30560396.47710-0.505403.230302.59750K562RBM15
TMEM104ENSG00000109066.9196.80320108.063600.864804.714003.58160K562RBM22
TMEM104ENSG00000109066.9194.99340105.366600.887904.535202.62160K562RBM34
TMEM104ENSG00000109066.9233.58160160.421500.542002.502001.56310K562RCC2
TMEM104ENSG00000109066.9197.70670113.727400.797704.009402.65960K562NELFE
TMEM104ENSG00000109066.9308.86190188.788800.710102.675101.87480K562RPS19
TMEM104ENSG00000109066.9494.34090333.247700.568804.111802.78260K562SAFB
TMEM104ENSG00000109066.9143.1000066.399301.107705.713304.45490K562SF3B4
TMEM104ENSG00000109066.9261.60930152.074200.782504.323502.95740K562SRFBP1
TMEM104ENSG00000109066.9247.79830110.521701.164708.406307.18100K562SRSF1
TMEM104ENSG00000109066.9169.46540104.396100.698803.010701.90620K562SRSF5
TMEM104ENSG00000109066.9490.70330375.091100.387502.403601.63850K562SYNCRIP
TMEM104ENSG00000109066.9330.41830111.840601.5627016.2967014.30260K562TARDBP
TMEM104ENSG00000109066.9227.73240107.886701.077707.323205.88770K562TIA1
TMEM104ENSG00000109066.9185.50760105.903400.808603.774702.46640K562TRA2A
TMEM104ENSG00000109066.9283.23770179.665000.656603.484702.40120K562TRIM56
TMEM104ENSG00000109066.9675.46280524.458100.364903.095802.33760K562UPF1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for TMEM104 is not available on ENCORE database.





2 RBPs can affect the splicing of TMEM104 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
MXETMEM104ENSG00000109066.9chr17+7277340272773514727816207278174272772638727727167278492772785009-0.157000.000030.001242includedK562DROSHA
MXETMEM104ENSG00000109066.9chr17+7277340272773514727849277278500972772638727727167278633872786435-0.186000.001340.099642includedHepG2DDX59

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for TMEM104 is not avaliable on ENCORE database.