PTPRM

General Information

Gene Name       : PTPRM
Gene ID             : ENSG00000173482.16
Essential Gene : No

Functions

Localization

Domains (AlphaFold: PTPRM)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PTPRMENSG00000173482.160.540.490.52ENCSR000AEF
HepG2PTPRMENSG00000173482.1616.9419.2618.10ENCSR985KAT
K562PTPRMENSG00000173482.160.140.030.09ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PTPRM is not avaliable on ENCORE database.



Proteins bound to RNA
  • PTPRM RNA is bound by 24 proteins.  







eCLIP assay for PTPRM is not avaliable on ENCORE database.





24 proteins are bound to PTPRM RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr1884064868406604+3'-UTR3.246293.26655HepG2LSM11
chr1880696838069737+3'-UTR,CDS,intron-Proximal4.176668.51432HepG2BCLAF1
chr1875675197567609+5'-UTR4.6436812.23732HepG2DDX3X
chr1875676097567658+5'-UTR4.495956.30794HepG2DDX3X
chr1875673557567473+5'-UTR4.3446318.74098HepG2DDX3X
chr1881136778113714+CDS3.734405.76104HepG2BCLAF1
chr1880887478088860+CDS,intron-Proximal3.986053.58932HepG2AGGF1
chr1878882667888295+CDS3.533783.28366HepG2BCLAF1
chr1879551217955215+CDS4.146023.05512HepG2PRPF4
chr1879265647926603+CDS,intron-Proximal3.020925.41373HepG2PPIG
chr1883782038378267+CDS,intron-Proximal3.848777.46684HepG2SF3A3
chr1881137208113758+CDS,intron-Proximal3.464129.03865HepG2BCLAF1
chr1879265647926600+CDS,intron-Proximal3.242564.25541HepG2GRWD1
chr1881437508143779+CDS,intron-Proximal3.416797.39995HepG2BCLAF1
chr1882440558244092+CDS,intron-Proximal5.1327314.17165HepG2BCLAF1
chr1880857728085870+CDS3.254997.17463HepG2EIF3H
chr1880856738085720+CDS3.936503.26547HepG2HLTF
chr1880697378069823+CDS3.5128710.92329HepG2BCLAF1
chr1883708958370909+CDS3.469143.87469HepG2BCLAF1
chr1879065267906581+CDS3.200546.00907HepG2PPIG
chr1882533078253338+CDS,intron-Distal3.567343.68471HepG2BCLAF1
chr1883781998378276+CDS,intron-Proximal4.762283.31322HepG2SF3B4
chr1882532298253261+CDS,intron-Distal3.353485.15500HepG2BCLAF1
chr1879554057955413+CDS,intron-Proximal3.522244.74886HepG2BCLAF1
chr1880765038076553+CDS3.374888.20757HepG2BCLAF1
chr1879265947926667+CDS3.061334.83845HepG2EIF3H
chr1879553337955381+CDS4.176897.05872HepG2PPIG
chr1879266347926658+CDS4.300625.79432HepG2BCLAF1
chr1883191758319198+CDS,intron-Proximal3.630113.87469HepG2BCLAF1
chr1880887548088847+CDS4.3942121.30803HepG2BCLAF1
chr1880856688085711+CDS,intron-Proximal3.763856.06436HepG2BCLAF1
chr1880887738088849+CDS3.987826.66963HepG2EIF3H
chr1883764988376564+CDS4.580314.94878HepG2GRWD1
chr1879065147906581+CDS3.033764.89942HepG2GRWD1
chr1881147878114811+CDS,intron-Proximal3.904303.79347HepG2GRWD1
chr1883765908376677+CDS,intron-Proximal3.891227.56654HepG2PRPF8
chr1879065047906581+CDS3.121409.23360HepG2BCLAF1
chr1879551217955186+CDS3.4673010.40328HepG2BCLAF1
chr1880699618069993+CDS,intron-Proximal3.230924.79538HepG2BCLAF1
chr1883791688379225+CDS3.314704.06531HepG2GRWD1
chr1879553947955412+CDS3.364553.57687HepG2EIF3H
chr1879553187955386+CDS4.321418.19556HepG2BCLAF1
chr1880887708088850+CDS,intron-Proximal5.5472910.41518HepG2PPIG
chr1881134838113521+CDS,intron-Proximal4.297023.82973HepG2HLTF
chr1878881057888168+CDS3.517524.21853HepG2EIF3D
chr1880858498085870+CDS3.376634.56058HepG2BCLAF1
chr1879266037926679+CDS4.186458.98325HepG2PPIG
chr1880292868029458+intron-Distal3.904803.65412HepG2HNRNPK
chr1876001577600226+intron-Distal3.123505.12506HepG2SUGP2
chr1878144477814518+intron-Distal4.022844.03915HepG2SUGP2
chr1883771938377247+intron-Distal3.211364.18806HepG2U2AF2
chr1877264897726543+intron-Distal4.092613.30440HepG2QKI
chr1876335027633601+intron-Distal4.621414.57427HepG2PCBP2
chr1877265657726654+intron-Distal4.923816.58335HepG2QKI
chr1881081448108286+intron-Distal4.087283.55640HepG2QKI
chr1876233667623445+intron-Distal4.209844.05848HepG2QKI
chr1878139197814014+intron-Distal4.595255.31925HepG2QKI
chr1881460368146111+intron-Distal3.588734.08528HepG2SUGP2
chr1876014037601463+intron-Distal4.143823.29248HepG2SUGP2
chr1875779027577991+intron-Distal4.214504.61447HepG2SUGP2
chr1877942257794244+intron-Distal4.240094.49585HepG2LSM11
chr1877987457798828+intron-Distal4.232044.51735HepG2QKI
chr1876662057666307+intron-Distal4.4093411.45834HepG2PTBP1
chr1877941497794198+intron-Distal3.912985.81997HepG2LSM11
chr1876591627659230+intron-Distal4.418557.14963HepG2HNRNPL
chr1877205857720661+intron-Distal4.906005.05488HepG2QKI
chr1876034307603585+intron-Distal4.521419.77080HepG2HNRNPM
chr1883582168358317+intron-Distal5.580446.64534HepG2HNRNPL
chr1882088858209061+intron-Distal4.588545.79972HepG2RBFOX2
chr1877053047705416+intron-Distal3.701827.98298HepG2PTBP1
chr1881525898152685+intron-Distal4.785325.75114HepG2PTBP1
chr1877941987794225+intron-Distal5.088728.87992HepG2LSM11
chr1876888397688926+intron-Distal4.280318.47823HepG2XPO5
chr1880292018029471+intron-Distal4.5795210.47447HepG2PCBP2
chr1883774648377511+intron-Distal3.911973.20552HepG2KHSRP
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PTPRM is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PTPRM is not available on ENCORE database.

  • 103 RBPs can affect the levels of PTPRM.  








The Knockdown/knockout RNA-Seq assay for PTPRM is not available on ENCORE database.





103 RBPs can affect the gene expression of PTPRM :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PTPRMENSG00000173482.121245.939401566.44010-0.330302.660301.60620HepG2AATF
PTPRMENSG00000173482.122950.611202136.383800.4657010.368409.34810HepG2ACO1
PTPRMENSG00000173482.121091.650801600.56320-0.552105.725504.35910HepG2ADAR
PTPRMENSG00000173482.122708.782102146.122800.335804.545903.58060HepG2AKAP8L
PTPRMENSG00000173482.121197.627501597.06590-0.415203.190202.34640HepG2ASCC1
PTPRMENSG00000173482.122790.823702257.285500.306004.694403.84110HepG2AUH
PTPRMENSG00000173482.122525.987101275.132700.9861015.7046013.84050HepG2BCLAF1
PTPRMENSG00000173482.124519.652802153.119601.0697026.9393025.39370HepG2BOP1
PTPRMENSG00000173482.122802.814901899.712500.561007.485205.54900HepG2BUD13
PTPRMENSG00000173482.123977.366501972.902501.0114031.3264029.31320HepG2CALR
PTPRMENSG00000173482.124827.639302946.041700.712407.314905.71320HepG2CCAR1
PTPRMENSG00000173482.123147.915501517.319201.0528020.2050018.34510HepG2CIRBP
PTPRMENSG00000173482.123596.269101976.743100.8633016.1236014.62990HepG2CPSF6
PTPRMENSG00000173482.122855.776502087.987000.451704.342802.97220HepG2CPSF7
PTPRMENSG00000173482.121667.329602082.68570-0.320904.000403.25350HepG2CELF1
PTPRMENSG00000173482.123822.642102239.237800.7715037.0416034.95060HepG2DAZAP1
PTPRMENSG00000173482.124803.851401728.093401.4749050.1026047.77120HepG2DDX21
PTPRMENSG00000173482.122267.815801691.209200.423105.142203.88810HepG2DDX24
PTPRMENSG00000173482.122379.946501350.005900.817909.345707.16650HepG2DDX27
PTPRMENSG00000173482.122588.135201442.701200.8430011.066509.64410HepG2DDX55
PTPRMENSG00000173482.123263.359802281.708600.516106.029804.59240HepG2DDX5
PTPRMENSG00000173482.122322.944601554.446700.579507.968506.39160HepG2DHX30
PTPRMENSG00000173482.123389.573402043.847600.7297023.8397022.33380HepG2DKC1
PTPRMENSG00000173482.122387.792801611.627200.5671011.5674010.21110HepG2DNAJC21
PTPRMENSG00000173482.125106.076701526.885601.7415051.2641049.01950HepG2EIF2S1
PTPRMENSG00000173482.122251.793401526.205200.561006.190604.87740HepG2EIF3D
PTPRMENSG00000173482.122094.609801631.996500.359903.883202.62960HepG2EIF3G
PTPRMENSG00000173482.127904.021501687.413102.2277070.8625067.78100HepG2EIF4A3
PTPRMENSG00000173482.122719.048702209.284000.299404.587303.55080HepG2EIF4G1
PTPRMENSG00000173482.123461.878302116.327800.709904.925403.85730HepG2EIF4G2
PTPRMENSG00000173482.123147.416802196.706100.518705.748404.22870HepG2ESF1
PTPRMENSG00000173482.123099.379402087.310200.570208.978907.49230HepG2EWSR1
PTPRMENSG00000173482.122402.742601646.883400.544807.499505.78610HepG2FASTKD2
PTPRMENSG00000173482.124216.094502561.112500.719008.144406.90080HepG2FIP1L1
PTPRMENSG00000173482.122398.169501364.452000.8135015.2861013.50850HepG2FUBP3
PTPRMENSG00000173482.122230.933101702.453400.389903.103602.37080HepG2FXR1
PTPRMENSG00000173482.123707.381401676.593201.1448024.1381021.67580HepG2G3BP2
PTPRMENSG00000173482.121887.874101358.893400.474204.519703.36750HepG2GEMIN5
PTPRMENSG00000173482.122448.654601567.246600.643708.187406.43430HepG2GNB2L1
PTPRMENSG00000173482.123256.199502240.962200.539004.933204.09380HepG2GPKOW
PTPRMENSG00000173482.122114.889401627.068600.378203.721202.98830HepG2HNRNPA1
PTPRMENSG00000173482.124388.788001809.860401.2778038.0994035.86570HepG2HNRNPC
PTPRMENSG00000173482.124850.083702138.576101.1813028.0696026.41150HepG2HNRNPLL
PTPRMENSG00000173482.122184.476001766.531500.306302.490501.58510HepG2HNRNPM
PTPRMENSG00000173482.123512.106101605.353401.129309.972808.77660HepG2IGF2BP2
PTPRMENSG00000173482.123058.779201506.497701.021705.152103.82860HepG2IGF2BP3
PTPRMENSG00000173482.122776.965601836.478300.5965020.9919019.18870HepG2ILF2
PTPRMENSG00000173482.123707.580001703.047401.1223021.6263019.88220HepG2MAGOH
PTPRMENSG00000173482.121668.484801300.279400.359602.990401.31240HepG2MARK2
PTPRMENSG00000173482.123868.988302071.961200.9009019.9570018.04590HepG2MSI2
PTPRMENSG00000173482.124970.961302180.698401.1886015.1270012.88070HepG2MTPAP
PTPRMENSG00000173482.123238.311301740.033400.8960014.5276011.79040HepG2NAA15
PTPRMENSG00000173482.121815.674901388.189100.387203.716202.05950HepG2NIP7
PTPRMENSG00000173482.124761.047201896.133401.3281038.9701036.70480HepG2NSUN2
PTPRMENSG00000173482.123902.637801561.155701.3217029.0121026.75060HepG2PABPC4
PTPRMENSG00000173482.121366.858801779.54520-0.380605.654904.50430HepG2PARN
PTPRMENSG00000173482.122232.616201612.877600.469009.392708.38280HepG2PCBP1
PTPRMENSG00000173482.122512.280401603.567000.6476014.6881013.06500HepG2PPIL4
PTPRMENSG00000173482.121445.644201774.80840-0.296003.721502.83630HepG2PRPF4
PTPRMENSG00000173482.121599.425001113.176100.522805.148504.08120HepG2PRPF8
PTPRMENSG00000173482.121424.089702250.14490-0.6600017.5328016.30740HepG2PUM1
PTPRMENSG00000173482.122430.445201777.384600.451406.887005.96680HepG2QKI
PTPRMENSG00000173482.122958.346701796.171100.719804.742703.83340HepG2RAVER1
PTPRMENSG00000173482.122222.347601596.404200.477203.197701.35900HepG2RBM14
PTPRMENSG00000173482.124792.843903389.580500.499705.602404.43480HepG2RBM15
PTPRMENSG00000173482.121614.807802166.16520-0.423806.659605.93910HepG2RBM22
PTPRMENSG00000173482.122153.428801613.118200.416704.837403.96800HepG2RBM25
PTPRMENSG00000173482.122003.605001503.227300.414403.952402.68230HepG2RCC2
PTPRMENSG00000173482.122268.409901826.466700.312504.369603.71760HepG2NELFE
PTPRMENSG00000173482.123521.733202543.220400.469504.882104.00820HepG2RPLP0
PTPRMENSG00000173482.123903.048701763.568901.1460013.4524011.54140HepG2RPS10
PTPRMENSG00000173482.122204.315601485.055300.569708.302807.30490HepG2RPS19
PTPRMENSG00000173482.123117.635801707.340000.8686015.7501013.96100HepG2RPS2
PTPRMENSG00000173482.122949.097801997.519000.562004.362403.35710HepG2RPS3A
PTPRMENSG00000173482.121705.236501101.186000.630806.399805.25940HepG2RRP9
PTPRMENSG00000173482.122408.887101601.073700.589206.748005.80750HepG2SAFB2
PTPRMENSG00000173482.122732.138501490.499600.8741015.0835013.00580HepG2SERBP1
PTPRMENSG00000173482.122026.108403095.49810-0.611503.598902.82640HepG2SF3A3
PTPRMENSG00000173482.122724.678902032.512500.422706.079905.10340HepG2SLBP
PTPRMENSG00000173482.123171.487101751.669100.856304.205602.24770HepG2SLTM
PTPRMENSG00000173482.125183.991902446.596801.0832066.5449064.92790HepG2SRFBP1
PTPRMENSG00000173482.123563.826901783.472200.9986046.9929045.56200HepG2SRSF1
PTPRMENSG00000173482.122446.436402092.899500.225102.895702.25590HepG2SRSF5
PTPRMENSG00000173482.121516.271002319.50010-0.6133014.8083013.42110HepG2SRSF7
PTPRMENSG00000173482.124182.716502124.212800.9774048.0963046.60240HepG2SSB
PTPRMENSG00000173482.121715.537303136.11240-0.8703011.613709.26090HepG2SSRP1
PTPRMENSG00000173482.124095.958201728.669101.2444037.9991035.11520HepG2SUPT6H
PTPRMENSG00000173482.123217.469801436.258901.1635021.1897019.63240HepG2SUPV3L1
PTPRMENSG00000173482.124236.566901603.123501.4019024.3298022.89490HepG2TAF15
PTPRMENSG00000173482.123975.385602083.999200.9316019.5546017.94890HepG2TARDBP
PTPRMENSG00000173482.122476.160201472.978700.749303.356102.43960HepG2TIA1
PTPRMENSG00000173482.122971.051101746.809400.7662018.2186017.14390HepG2TIAL1
PTPRMENSG00000173482.122581.376901762.615500.550308.682907.77100HepG2TRIM56
PTPRMENSG00000173482.122787.023102192.054900.346302.653001.83290HepG2UBE2L3
PTPRMENSG00000173482.121733.629301315.363500.398202.542601.58350HepG2UPF2
PTPRMENSG00000173482.123046.767702650.415100.201002.535801.95720HepG2UTP3
PTPRMENSG00000173482.122060.155101413.837200.543005.916204.86750HepG2XRN2
PTPRMENSG00000173482.124633.189903019.231400.6177028.0230026.74550HepG2ZNF622
PTPRMENSG00000173482.121100.019601793.72920-0.705403.150101.76010HepG2ZRANB2
PTPRMENSG00000173482.1231.450204.395302.838904.058802.90970K562KRR1
PTPRMENSG00000173482.1225.101805.021002.321602.301201.50410K562METAP2
PTPRMENSG00000173482.1221.036803.224902.705502.782601.94900K562PCBP3
PTPRMENSG00000173482.1214.837602.474002.584202.128301.42650K562POLR2G
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PTPRM is not available on ENCORE database.





19 RBPs can affect the splicing of PTPRM :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPTPRMENSG00000173482.12chr18+8248147824817482478428247917825322482534120.349000.000020.00077includedHepG2U2AF1
SEPTPRMENSG00000173482.12chr18+8371757837180883709308371004837604383761980.258000.000180.05166includedHepG2CDC40
SEPTPRMENSG00000173482.12chr18+8371757837180883709308371004837604383761980.085000.003180.06270includedHepG2SRSF1
A3SSPTPRMENSG00000173482.12chr18+8394411839460983944738394609838706983872330.082000.003080.06480longerHepG2U2AF2
RIPTPRMENSG00000173482.12chr18+837645983784128376459837659583782628378412-0.165000.001100.04651excludedHepG2AKAP1
RIPTPRMENSG00000173482.12chr18+837645983784128376459837659583782628378412-0.195000.000110.01070excludedHepG2DDX6
RIPTPRMENSG00000173482.12chr18+8376459837841283764598376595837826283784120.183000.000000.00059includedHepG2TBRG4
RIPTPRMENSG00000173482.12chr18+8376459837841283764598376595837826283784120.163000.001580.03250includedHepG2PCBP2
RIPTPRMENSG00000173482.12chr18+837645983784128376459837659583782628378412-0.198000.000000.00047excludedHepG2PRPF4
RIPTPRMENSG00000173482.12chr18+8376459837841283764598376595837826283784120.251000.000010.00081includedHepG2TIA1
RIPTPRMENSG00000173482.12chr18+8376459837841283764598376595837826283784120.179000.000570.05082includedHepG2EFTUD2
RIPTPRMENSG00000173482.12chr18+8376459837841283764598376595837826283784120.181000.000430.07900includedHepG2EIF3D
RIPTPRMENSG00000173482.12chr18+8376459837841283764598376595837826283784120.298000.000000.00006includedHepG2PCBP1
RIPTPRMENSG00000173482.12chr18+8376459837841283764598376595837826283784120.378000.000000.00000includedHepG2SRSF1
RIPTPRMENSG00000173482.12chr18+8376459837841283764598376595837826283784120.220000.000120.06148includedHepG2FAM120A
RIPTPRMENSG00000173482.12chr18+8376459837841283764598376595837826283784120.200000.000070.00137includedHepG2TAF15
RIPTPRMENSG00000173482.12chr18+837645983784128376459837659583782628378412-0.073000.013200.09762excludedHepG2U2AF1
RIPTPRMENSG00000173482.12chr18+8376459837841283764598376595837826283784120.199000.000850.01810includedHepG2TIAL1
RIPTPRMENSG00000173482.12chr18+8376459837841283764598376595837826283784120.194000.002550.03929includedHepG2SRSF9
RIPTPRMENSG00000173482.12chr18+8376459837841283764598376595837826283784120.212000.000090.05691includedHepG2GTF2F1
RIPTPRMENSG00000173482.12chr18+8376459837841283764598376595837826283784120.090000.001760.07346includedHepG2LARP4
MXEPTPRMENSG00000173482.12chr18+824814782481748253224825341282478428247917829636582964530.139000.000310.008221includedHepG2U2AF1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PTPRM is not avaliable on ENCORE database.