PRODH2

General Information

Gene Name       : PRODH2
Gene ID             : ENSG00000250799.9
Essential Gene : No

Functions

Localization

Domains (AlphaFold: PRODH2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PRODH2ENSG00000250799.90.000.000.00ENCSR000AEF
HepG2PRODH2ENSG00000250799.946.4614.9830.72ENCSR985KAT
K562PRODH2ENSG00000250799.90.000.000.00ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PRODH2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • PRODH2 RNA is bound by 22 proteins.  







eCLIP assay for PRODH2 is not avaliable on ENCORE database.





22 proteins are bound to PRODH2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr193629091936290966-3'-UTR,CDS,intron-Distal3.261523.21969HepG2ZC3H11A
chr193629100736291069-3'-UTR,CDS,intron-Distal3.161583.07769HepG2SRSF1
chr193629103136291107-3'-UTR,CDS,intron-Distal3.310938.64184HepG2LSM11
chr193629092836290972-3'-UTR,CDS,intron-Distal3.029813.83732HepG2LSM11
chr193629097236291031-3'-UTR,CDS,intron-Distal3.146438.07911HepG2LSM11
chr193629760636297662-CDS,intron-Distal,intron-Proximal3.257013.49429HepG2SRSF1
chr193629396236293979-CDS,intron-Distal4.011468.12130HepG2PPIG
chr193630301336303077-CDS,intron-Distal,intron-Proximal4.0382438.20631HepG2PRPF8
chr193629800136298022-CDS,intron-Distal3.109746.92518HepG2PPIG
chr193630327836303369-CDS,intron-Distal3.145563.28089HepG2SRSF7
chr193630323036303300-CDS,intron-Distal,intron-Proximal3.570484.96115HepG2SRSF1
chr193630316036303245-CDS,intron-Distal,intron-Proximal3.8498730.64009HepG2BUD13
chr193630291836302940-CDS,intron-Distal,intron-Proximal4.8047032.31792HepG2EFTUD2
chr193630286536302951-CDS,intron-Distal,intron-Proximal3.136769.47766HepG2BUD13
chr193630374336303795-CDS,intron-Distal,intron-Proximal3.526147.42472HepG2NCBP2
chr193630285736302879-CDS,intron-Distal,intron-Proximal3.9464821.76853HepG2EFTUD2
chr193629736236297428-CDS,intron-Distal,intron-Proximal4.228333.48299HepG2SRSF9
chr193630312236303258-CDS,intron-Distal,intron-Proximal3.056807.82533HepG2RBFOX2
chr193629772836297797-CDS,intron-Distal,intron-Proximal4.7327828.78439HepG2SF3A3
chr193630308136303132-CDS,intron-Distal3.360724.93187HepG2SRSF1
chr193630291436302946-CDS,intron-Distal,intron-Proximal4.1291813.07265HepG2PPIG
chr193629799836298042-CDS,intron-Distal,intron-Proximal4.727575.51162HepG2U2AF2
chr193630294036302950-CDS,intron-Distal,intron-Proximal5.0641527.23737HepG2EFTUD2
chr193630288236302914-CDS,intron-Distal,intron-Proximal3.7255719.71865HepG2PPIG
chr193630333736303381-CDS,intron-Distal3.263639.89337HepG2PPIG
chr193630308336303156-CDS,intron-Distal4.4184044.95825HepG2EFTUD2
chr193630285636302942-CDS,intron-Distal,intron-Proximal3.9959612.56928HepG2SRSF1
chr193630316636303274-CDS,intron-Distal,intron-Proximal3.1710025.69182HepG2PPIG
chr193629733136297423-CDS,intron-Distal,intron-Proximal3.072497.69978HepG2UCHL5
chr193630286036302918-CDS,intron-Distal,intron-Proximal5.143167.49559HepG2SRSF9
chr193629768736297728-CDS,intron-Distal,intron-Proximal3.090444.60500HepG2SF3A3
chr193630308736303156-CDS,intron-Distal3.065966.65734HepG2PRPF4
chr193630294936303013-CDS,intron-Distal,intron-Proximal5.1827943.35025HepG2PRPF8
chr193629741936297483-CDS,intron-Distal,intron-Proximal3.147255.78613HepG2SRSF1
chr193630327436303303-CDS,intron-Distal3.7290610.14528HepG2PPIG
chr193630324536303279-CDS,intron-Distal,intron-Proximal3.628235.19978HepG2BUD13
chr193630287936302918-CDS,intron-Distal,intron-Proximal5.0051937.35217HepG2EFTUD2
chr193630302636303042-CDS,intron-Distal,intron-Proximal5.6357720.92011HepG2EFTUD2
chr193630286936302938-CDS,intron-Distal,intron-Proximal3.281366.61201HepG2GRWD1
chr193630367136303743-CDS,intron-Distal3.805249.61734HepG2NCBP2
chr193629733236297431-CDS,intron-Distal,intron-Proximal4.1194536.39499HepG2PPIG
chr193630315636303266-CDS,intron-Distal,intron-Proximal5.32206400.00000HepG2EFTUD2
chr193630293836303014-CDS,intron-Distal,intron-Proximal3.5757113.52673HepG2SF3A3
chr193629773936297808-intron-Distal,intron-Proximal4.8134614.80705HepG2SF3B4
chr193630223936302345-intron-Distal4.0205312.41782HepG2PTBP1
chr193629752336297574-intron-Distal,intron-Proximal4.153924.69096HepG2RBM5
chr193630320336303250-intron-Distal,intron-Proximal3.624153.12708HepG2RBM5
chr193630237336302468-intron-Distal4.3916411.64729HepG2PTBP1
chr193630317836303254-intron-Distal,intron-Proximal3.058086.12694HepG2RBM15
chr193630346736303527-intron-Distal,intron-Proximal4.542018.03431HepG2SF3A3
chr193629773336297794-intron-Distal,intron-Proximal3.0716712.98263HepG2EFTUD2
chr193629677436296937-intron-Distal3.451145.96194HepG2PCBP2
chr193630321036303259-intron-Distal,intron-Proximal4.2524614.81562HepG2PRPF8
chr193630347636303522-intron-Distal,intron-Proximal3.790373.38341HepG2RBM5
chr193630295836303014-intron-Distal,intron-Proximal3.5848912.12228HepG2BUD13
chr193630295036303021-intron-Distal,intron-Proximal6.19966400.00000HepG2EFTUD2
chr193629751136297545-intron-Distal,intron-Proximal4.350996.25632HepG2SF3A3
chr193629170936291760-intron-Distal3.668154.14989HepG2ILF3
chr193629558036295674-intron-Distal3.009063.57155HepG2ILF3
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PRODH2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PRODH2 is not available on ENCORE database.

  • 103 RBPs can affect the levels of PRODH2.  








The Knockdown/knockout RNA-Seq assay for PRODH2 is not available on ENCORE database.





103 RBPs can affect the gene expression of PRODH2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PRODH2ENSG00000250799.5101.35520457.54950-2.174504.735403.36680HepG2AATF
PRODH2ENSG00000250799.5124.79930966.30290-2.95290126.65390124.15690HepG2ACO1
PRODH2ENSG00000250799.5121.932901744.98730-3.8391010.296709.33580HepG2AKAP1
PRODH2ENSG00000250799.5679.08470970.78140-0.515605.043204.03370HepG2AKAP8L
PRODH2ENSG00000250799.5848.278401037.79320-0.290902.477101.82080HepG2AUH
PRODH2ENSG00000250799.5857.23170295.269901.537608.204606.76070HepG2BCLAF1
PRODH2ENSG00000250799.5377.93690157.020601.267105.091504.31010HepG2BOP1
PRODH2ENSG00000250799.5535.74750144.138701.8940013.4881012.10210HepG2CPSF6
PRODH2ENSG00000250799.5530.96310229.260601.2115018.0642015.63930HepG2YBX3
PRODH2ENSG00000250799.5259.88520460.47910-0.825308.855907.83000HepG2CELF1
PRODH2ENSG00000250799.51151.16680495.143601.2171039.1281036.99790HepG2DAZAP1
PRODH2ENSG00000250799.5357.48900229.557600.638903.728202.39320HepG2DDX1
PRODH2ENSG00000250799.5807.76590473.947900.769108.649306.50780HepG2DDX47
PRODH2ENSG00000250799.51014.33170521.991900.9583012.1893010.24540HepG2DDX5
PRODH2ENSG00000250799.5306.705401436.60320-2.227705.385904.55010HepG2DDX6
PRODH2ENSG00000250799.5761.68220217.104701.810706.493805.04110HepG2DHX30
PRODH2ENSG00000250799.51188.26000924.470900.362104.170403.37290HepG2DKC1
PRODH2ENSG00000250799.5578.56170225.084301.3619015.8992014.34530HepG2DNAJC21
PRODH2ENSG00000250799.5702.82410223.143901.6551046.0542043.67810HepG2DNAJC2
PRODH2ENSG00000250799.5147.32050526.44490-1.8373017.9085015.85490HepG2EIF3D
PRODH2ENSG00000250799.5830.01620488.476200.764802.977702.11520HepG2EIF4G1
PRODH2ENSG00000250799.51014.69140467.931301.1166012.2023010.56840HepG2EIF4G2
PRODH2ENSG00000250799.5962.388501191.56170-0.308202.915302.30090HepG2ETF1
PRODH2ENSG00000250799.5416.81260944.18500-1.1797015.3608013.48650HepG2EWSR1
PRODH2ENSG00000250799.5156.33800851.74280-2.4457015.5553013.97800HepG2FIP1L1
PRODH2ENSG00000250799.5272.66670442.40270-0.698203.445802.19730HepG2FUS
PRODH2ENSG00000250799.5801.142201539.73420-0.942601.971901.38390HepG2FXR1
PRODH2ENSG00000250799.5301.82590468.70940-0.635004.223003.10450HepG2GEMIN5
PRODH2ENSG00000250799.5383.19500163.351901.230008.448007.37300HepG2GPKOW
PRODH2ENSG00000250799.5162.92150424.67870-1.382206.284304.11190HepG2HLTF
PRODH2ENSG00000250799.5375.50900227.241200.724501.944601.39160HepG2HNRNPA1
PRODH2ENSG00000250799.5663.00480252.779501.391002.934202.22230HepG2HNRNPC
PRODH2ENSG00000250799.5740.52120254.063101.5433036.6783034.58050HepG2HNRNPF
PRODH2ENSG00000250799.5884.54370451.042600.971607.263306.21780HepG2HNRNPL
PRODH2ENSG00000250799.5454.82730155.893401.5447015.2930013.97910HepG2HNRNPLL
PRODH2ENSG00000250799.5270.81640587.41710-1.117107.185405.76290HepG2HNRNPM
PRODH2ENSG00000250799.5541.30040251.107101.1080017.6810016.25350HepG2HNRNPU
PRODH2ENSG00000250799.5858.43670250.177501.7787042.5359040.25230HepG2IGF2BP1
PRODH2ENSG00000250799.5270.076701362.63410-2.335005.251903.91880HepG2IGF2BP3
PRODH2ENSG00000250799.5647.30940256.494901.3354030.3210028.23550HepG2ILF2
PRODH2ENSG00000250799.5705.79580307.057001.200606.192204.14720HepG2ILF3
PRODH2ENSG00000250799.5518.34920300.532500.786303.117201.83490HepG2KHDRBS1
PRODH2ENSG00000250799.51321.88690883.276100.5816012.4211010.44590HepG2KIF1C
PRODH2ENSG00000250799.5264.45450490.63960-0.891606.270705.01170HepG2LARP4
PRODH2ENSG00000250799.5294.95790424.14300-0.524003.534302.25180HepG2LARP7
PRODH2ENSG00000250799.5614.25950445.209000.464302.783401.56500HepG2LIN28B
PRODH2ENSG00000250799.5277.44090425.39310-0.616603.477901.56610HepG2LSM11
PRODH2ENSG00000250799.5563.515101548.64160-1.458503.151202.48090HepG2MATR3
PRODH2ENSG00000250799.5229.03270550.92010-1.266309.563807.73980HepG2METAP2
PRODH2ENSG00000250799.5411.06510688.94960-0.745004.548803.53100HepG2MSI2
PRODH2ENSG00000250799.5449.46870159.079601.498404.496503.24120HepG2MTPAP
PRODH2ENSG00000250799.5572.79230383.488500.578704.140102.39400HepG2NIP7
PRODH2ENSG00000250799.5767.51830490.982500.644405.399904.34140HepG2NOL12
PRODH2ENSG00000250799.5474.24200226.115901.068503.199001.64050HepG2NOLC1
PRODH2ENSG00000250799.5359.00640138.258701.376506.461705.34350HepG2NSUN2
PRODH2ENSG00000250799.51155.235501390.64840-0.267602.873602.25830HepG2PCBP1
PRODH2ENSG00000250799.5272.79530418.74590-0.618302.847301.79150HepG2PCBP2
PRODH2ENSG00000250799.51387.88500918.902200.594804.222502.09890HepG2PES1
PRODH2ENSG00000250799.5920.81190223.964702.0395032.0184029.75310HepG2PPIL4
PRODH2ENSG00000250799.5620.12110401.696800.626307.115005.94380HepG2PRPF4
PRODH2ENSG00000250799.5847.967701415.04160-0.7388016.6636015.53930HepG2PTBP1
PRODH2ENSG00000250799.5696.73050468.681500.571905.029404.25500HepG2PUF60
PRODH2ENSG00000250799.5752.61610497.521000.597108.821007.88910HepG2PUM1
PRODH2ENSG00000250799.5337.05150497.16080-0.560704.386403.55170HepG2PUM2
PRODH2ENSG00000250799.51192.83530984.231400.277203.033202.39540HepG2PUS1
PRODH2ENSG00000250799.52214.094501532.514700.530705.979205.10940HepG2QKI
PRODH2ENSG00000250799.557.82690403.94220-2.8043017.6871016.05170HepG2RAVER1
PRODH2ENSG00000250799.5556.00430826.19360-0.571406.117004.90320HepG2RBM15
PRODH2ENSG00000250799.5286.48010995.91760-1.7976051.2308049.54940HepG2RBM22
PRODH2ENSG00000250799.5652.653601574.80140-1.2708041.7107040.17040HepG2NELFE
PRODH2ENSG00000250799.51064.933601466.72070-0.461807.133106.21210HepG2RECQL
PRODH2ENSG00000250799.5722.07040397.081500.862603.614702.53550HepG2RPS10
PRODH2ENSG00000250799.5182.93910512.32790-1.4857014.0182012.77350HepG2RPS19
PRODH2ENSG00000250799.5895.68520316.663301.4999018.5478016.57850HepG2RPS3A
PRODH2ENSG00000250799.51244.41860223.612802.4763081.0839078.53390HepG2SAFB2
PRODH2ENSG00000250799.5549.44730298.180300.881704.200202.59550HepG2SART3
PRODH2ENSG00000250799.5755.55090300.542801.3299010.075307.40030HepG2SBDS
PRODH2ENSG00000250799.5330.332101199.76720-1.8608030.7793028.50490HepG2SF3A3
PRODH2ENSG00000250799.5362.49030154.280201.232305.145204.20540HepG2SF3B1
PRODH2ENSG00000250799.5763.081301473.23230-0.9491024.8582023.38800HepG2SF3B4
PRODH2ENSG00000250799.51556.37100449.382101.7921091.1224088.45930HepG2SLBP
PRODH2ENSG00000250799.5585.85270412.711900.505302.654001.71810HepG2SMNDC1
PRODH2ENSG00000250799.5836.72530393.887501.0869011.295208.25570HepG2SND1
PRODH2ENSG00000250799.5119.840501124.83880-3.23050149.21720146.98770HepG2SRFBP1
PRODH2ENSG00000250799.5282.524801537.73910-2.44440122.80900120.83400HepG2SRSF1
PRODH2ENSG00000250799.5738.58090462.748600.674402.672702.05470HepG2SRSF5
PRODH2ENSG00000250799.5786.07370249.615901.6549035.0621033.14830HepG2SRSF7
PRODH2ENSG00000250799.5355.278001251.03570-1.8161072.9942070.94670HepG2SRSF9
PRODH2ENSG00000250799.52100.06940976.603101.1045043.5206042.07410HepG2SSB
PRODH2ENSG00000250799.51076.02240568.545700.920303.743102.32370HepG2STAU1
PRODH2ENSG00000250799.5424.488401382.18960-1.7032058.5417056.38800HepG2TAF15
PRODH2ENSG00000250799.5456.32300152.055301.5854011.3342010.01710HepG2TARDBP
PRODH2ENSG00000250799.5325.22380243.938800.414802.066901.62170HepG2TIAL1
PRODH2ENSG00000250799.5714.42730246.182401.5370037.4310035.65730HepG2TRIM56
PRODH2ENSG00000250799.5228.83660728.38540-1.6704011.3412010.04700HepG2U2AF1
PRODH2ENSG00000250799.5948.48100484.646700.968603.613502.64980HepG2UBE2L3
PRODH2ENSG00000250799.5424.128501027.25930-1.2762033.9423032.20090HepG2UTP3
PRODH2ENSG00000250799.51052.28790283.662901.8912028.5805025.21530HepG2XPO5
PRODH2ENSG00000250799.5255.09100397.49040-0.639902.875501.59020HepG2XRCC5
PRODH2ENSG00000250799.5198.70960444.38270-1.161107.124405.49410HepG2XRCC6
PRODH2ENSG00000250799.5986.20320327.524501.5902011.006309.57710HepG2XRN2
PRODH2ENSG00000250799.5799.768101170.20710-0.549109.027008.18490HepG2ZNF622
PRODH2ENSG00000250799.5770.63990403.852900.932108.287705.93650HepG2ZRANB2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PRODH2 is not available on ENCORE database.





17 RBPs can affect the splicing of PRODH2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPRODH2ENSG00000250799.5chr19-3629309236293178362908913629112436293869362939800.197000.000100.01433includedHepG2G3BP1
SEPRODH2ENSG00000250799.5chr19-362930923629317836290891362911243629386936293980-0.341000.000000.00049excludedHepG2BCLAF1
SEPRODH2ENSG00000250799.5chr19-3629309236293178362908913629112436293869362939800.400000.000180.01930includedHepG2IGF2BP3
SEPRODH2ENSG00000250799.5chr19-362930923629317836290891362911243629386936293980-0.228000.000030.00284excludedHepG2PCBP1
SEPRODH2ENSG00000250799.5chr19-362930923629317836290891362911243629386936293980-0.187000.000750.03715excludedHepG2SF3B4
A3SSPRODH2ENSG00000250799.5chr19-3629733136297520362973313629749836297576362977320.127000.001350.08409longerHepG2SF3B4
A5SSPRODH2ENSG00000250799.5chr19-3629781236298023362979423629802336297576362977320.091000.000780.06326longerHepG2RBM22
RIPRODH2ENSG00000250799.5chr19-362973313629802336297331362974983629794236298023-0.153000.002130.07165excludedHepG2AKAP1
RIPRODH2ENSG00000250799.5chr19-3630303536303458363030353630317436303261363034580.291000.007550.09895includedHepG2PCBP2
RIPRODH2ENSG00000250799.5chr19-3630303536303458363030353630317436303261363034580.336000.000060.01274includedHepG2PRPF4
RIPRODH2ENSG00000250799.5chr19-3630303536303458363030353630317436303261363034580.490000.000010.00017includedHepG2PRPF8
RIPRODH2ENSG00000250799.5chr19-3630303536303458363030353630317436303261363034580.247000.001550.03170includedHepG2IGF2BP3
RIPRODH2ENSG00000250799.5chr19-3630303536303458363030353630317436303261363034580.546000.000010.00071includedHepG2FTO
RIPRODH2ENSG00000250799.5chr19-3630303536303458363030353630317436303261363034580.310000.000370.02464includedHepG2HNRNPA1
RIPRODH2ENSG00000250799.5chr19-3630303536303458363030353630317436303261363034580.157000.000350.00900includedHepG2G3BP1
RIPRODH2ENSG00000250799.5chr19-3630303536303458363030353630317436303261363034580.344000.000030.00342includedHepG2HNRNPC
RIPRODH2ENSG00000250799.5chr19-3630303536303458363030353630317436303261363034580.498000.000000.00001includedHepG2TIAL1
RIPRODH2ENSG00000250799.5chr19-3630303536303458363030353630317436303261363034580.446000.000010.00105includedHepG2HNRNPU
RIPRODH2ENSG00000250799.5chr19-3630303536303458363030353630317436303261363034580.254000.000000.00000includedHepG2SF3B4
RIPRODH2ENSG00000250799.5chr19-3630303536303458363030353630317436303261363034580.282000.000000.00003includedHepG2FUBP3
RIPRODH2ENSG00000250799.5chr19-3630303536303458363030353630317436303261363034580.331000.000000.00012includedHepG2HNRNPK
MXEPRODH2ENSG00000250799.5chr19-36293092362931783629386936293980362908913629112436297331362974980.214000.000020.004881includedHepG2BCLAF1
MXEPRODH2ENSG00000250799.5chr19-36293092362931783629386936293980362908913629112436297331362974980.106000.002210.061451includedHepG2PCBP1
MXEPRODH2ENSG00000250799.5chr19-36293092362931783629386936293980362908913629112436297331362974980.113000.002310.066901includedHepG2SF3B4

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PRODH2 is not avaliable on ENCORE database.