DTX3L

General Information

Gene Name       : DTX3L
Gene ID             : ENSG00000163840.9
Essential Gene : No

Functions

Localization

Domains (AlphaFold: DTX3L)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878DTX3LENSG00000163840.928.6525.7627.20ENCSR000AEF
HepG2DTX3LENSG00000163840.93.425.874.64ENCSR985KAT
K562DTX3LENSG00000163840.93.574.013.79ENCSR000AEO

Assays

1 Released experiments are available on ENCORE database.

Assay TypeExp_NameENCODE IDTarget labelBiosampleStatusLinked AntibodyControlsMethodNote
knockdown followed by RNA-seq DTX3L-BGRSLV03-RS293DTX3LRibo-STAMP-293TReleased   shRNAKD% = ,






  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  
  GeneName    Cell_Line    Method    Exp_ID    Control_ID    Sample_reps    Control_reps    KD%    Status    Project    Note  
DTX3LRibo-STAMP-293TshRNABGRSLV02-59,BGRSLV02-60BGRSLV02-1,BGRSLV02-2NotSatisfiedENCORE2
DTX3LRibo-STAMP-293TshRNADTX3L-BGRSLV03-21,DTX3L-BGRSLV03-22NT-BGRSLV03-1,NT-BGRSLV03-2,ReleasedENCORE2


  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for DTX3L is not avaliable on ENCORE database.



Proteins bound to RNA
  • DTX3L RNA is bound by 2 proteins.  







eCLIP assay for DTX3L is not avaliable on ENCORE database.





2 proteins are bound to DTX3L RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr3122293407122293503+3'-UTR4.549024.92383K562FAM120A
chr3122283456122283525+CDS,intron-Proximal4.193513.25089HepG2AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for DTX3L is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for DTX3L is not available on ENCORE database.

  • 127 RBPs can affect the levels of DTX3L.  








The Knockdown/knockout RNA-Seq assay for DTX3L is not available on ENCORE database.





127 RBPs can affect the gene expression of DTX3L :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
DTX3LENSG00000163840.5538.92180384.194100.488103.195902.05230HepG2AATF
DTX3LENSG00000163840.51208.33750578.715301.0620014.2517012.39810HepG2ABCF1
DTX3LENSG00000163840.5655.50760433.922000.595104.784403.51980HepG2ADAR
DTX3LENSG00000163840.5920.47200672.804800.452103.007401.92520HepG2AKAP8
DTX3LENSG00000163840.5965.59370520.663200.8910010.881209.48730HepG2AKAP8L
DTX3LENSG00000163840.5926.63070489.275000.9212010.705309.23390HepG2ASCC1
DTX3LENSG00000163840.5230.27320428.52370-0.896006.166104.74400HepG2BCCIP
DTX3LENSG00000163840.5586.07910433.705800.434303.077801.78000HepG2BUD13
DTX3LENSG00000163840.5882.79840464.841300.9252010.783309.34890HepG2CIRBP
DTX3LENSG00000163840.5254.18800582.07670-1.195309.332507.95790HepG2CNOT7
DTX3LENSG00000163840.5634.68340476.735400.412702.962101.82110HepG2CPSF7
DTX3LENSG00000163840.51146.72940581.574000.9794022.1957020.73380HepG2CELF1
DTX3LENSG00000163840.5494.97150625.34890-0.337302.921002.16170HepG2DAZAP1
DTX3LENSG00000163840.5593.33210479.280700.307902.522701.72330HepG2DDX19B
DTX3LENSG00000163840.5840.80100424.073000.9874013.3999012.04560HepG2DDX21
DTX3LENSG00000163840.5820.56600421.334800.961605.968804.88610HepG2DDX55
DTX3LENSG00000163840.5643.25250486.543900.402702.116701.56950HepG2DDX6
DTX3LENSG00000163840.51050.65750495.793001.0834025.2837023.74580HepG2DKC1
DTX3LENSG00000163840.5534.76790362.422900.561103.481602.45380HepG2EEF2
DTX3LENSG00000163840.5555.67230390.375900.509302.713901.62000HepG2AGO1
DTX3LENSG00000163840.5616.56860439.117200.489604.010702.60670HepG2EIF2S2
DTX3LENSG00000163840.5590.84180400.363200.561404.733603.36370HepG2EIF3G
DTX3LENSG00000163840.5973.87850516.981600.913509.731608.54600HepG2EIF4A3
DTX3LENSG00000163840.5730.20770503.302500.536802.905102.20080HepG2EIF4B
DTX3LENSG00000163840.5968.53600616.933000.6506010.149808.74170HepG2EIF4G1
DTX3LENSG00000163840.5677.03950506.403400.418903.116602.23270HepG2EWSR1
DTX3LENSG00000163840.5765.47270584.394500.389302.199901.51000HepG2FIP1L1
DTX3LENSG00000163840.5678.80300418.285200.698404.444903.14630HepG2GNB2L1
DTX3LENSG00000163840.51096.29540755.775600.536504.218503.43940HepG2GPKOW
DTX3LENSG00000163840.5762.89440441.117700.790208.743407.68970HepG2HNRNPA1
DTX3LENSG00000163840.5509.00600721.24700-0.502803.435402.74270HepG2HNRNPLL
DTX3LENSG00000163840.5328.49910487.42270-0.569305.501004.66840HepG2HNRNPU
DTX3LENSG00000163840.5918.82820675.006700.444804.485303.58220HepG2IGF2BP1
DTX3LENSG00000163840.51048.53890491.827601.0921015.2046013.77150HepG2IGF2BP2
DTX3LENSG00000163840.5399.00560497.88530-0.319402.240601.57220HepG2ILF2
DTX3LENSG00000163840.5672.67430494.665800.443402.250701.35920HepG2KHSRP
DTX3LENSG00000163840.5273.74510430.32480-0.652603.755802.34150HepG2LIN28B
DTX3LENSG00000163840.5740.96530521.712600.506103.414202.68550HepG2MAGOH
DTX3LENSG00000163840.51042.79060524.645900.9909011.133909.93020HepG2MATR3
DTX3LENSG00000163840.5670.22360473.106600.502404.252903.26080HepG2MSI2
DTX3LENSG00000163840.5770.34970478.296700.687505.947404.89970HepG2PABPC4
DTX3LENSG00000163840.5648.50340467.688000.471504.822404.05640HepG2PCBP1
DTX3LENSG00000163840.5714.67600504.740200.501602.547901.55160HepG2PCBP2
DTX3LENSG00000163840.5609.62390324.988900.907408.043406.75010HepG2PRPF8
DTX3LENSG00000163840.5795.00790475.917600.7402010.340409.41390HepG2PTBP1
DTX3LENSG00000163840.5811.51380628.355300.368904.130303.43690HepG2PUM1
DTX3LENSG00000163840.5680.44500527.834700.366303.375802.71220HepG2PUS1
DTX3LENSG00000163840.5407.27120515.37180-0.339601.920501.38530HepG2QKI
DTX3LENSG00000163840.5919.51990487.161100.916405.953504.94620HepG2RAVER1
DTX3LENSG00000163840.5934.23110657.797300.506003.481302.52900HepG2RBM15
DTX3LENSG00000163840.51234.44350692.823600.833208.308607.52310HepG2RBM22
DTX3LENSG00000163840.5844.11910529.627700.672409.272408.38680HepG2NELFE
DTX3LENSG00000163840.5648.26350493.317800.394003.391302.71730HepG2RECQL
DTX3LENSG00000163840.51258.03480738.387400.7686010.286309.11260HepG2RPLP0
DTX3LENSG00000163840.5455.79930286.277200.670905.208704.39590HepG2RPS19
DTX3LENSG00000163840.5594.56200455.619500.383902.491001.72970HepG2RPS2
DTX3LENSG00000163840.5640.84010465.049200.462502.869701.77350HepG2RPS5
DTX3LENSG00000163840.5500.85530321.477700.639603.750502.85260HepG2RRP9
DTX3LENSG00000163840.5555.49770287.317200.951009.341907.64380HepG2SERBP1
DTX3LENSG00000163840.5722.74480495.442200.544706.059605.24190HepG2SF3B4
DTX3LENSG00000163840.51261.23530794.347200.666904.429703.43040HepG2SNRNP70
DTX3LENSG00000163840.51337.01750782.532200.7727018.3954017.40570HepG2SRFBP1
DTX3LENSG00000163840.51041.40680517.154601.0098022.2429021.17810HepG2SRSF1
DTX3LENSG00000163840.5794.64190584.439200.443204.705803.92610HepG2SRSF5
DTX3LENSG00000163840.51117.67990420.750201.4094046.5307044.82000HepG2SRSF9
DTX3LENSG00000163840.51743.74990679.446801.3597056.9570055.36950HepG2SSB
DTX3LENSG00000163840.5713.06370455.243300.647303.651202.25960HepG2SUB1
DTX3LENSG00000163840.5942.97290664.673100.504506.983506.07370HepG2SUCLG1
DTX3LENSG00000163840.51020.73420419.421601.2830016.3194014.91830HepG2SUPV3L1
DTX3LENSG00000163840.5444.88910281.117100.662203.788602.64170HepG2TFIP11
DTX3LENSG00000163840.5552.29440427.115500.370702.554501.74830HepG2TIA1
DTX3LENSG00000163840.5662.77860473.602900.484704.260903.66810HepG2TIAL1
DTX3LENSG00000163840.5786.65070499.988900.653705.881004.98140HepG2U2AF1
DTX3LENSG00000163840.51051.89450579.018300.861202.380201.47410HepG2U2AF2
DTX3LENSG00000163840.5896.03540612.098500.549702.600901.78980HepG2UBE2L3
DTX3LENSG00000163840.5758.75210527.236800.525106.528905.53090HepG2UPF1
DTX3LENSG00000163840.5753.23340541.926900.474905.012103.64300HepG2UTP18
DTX3LENSG00000163840.5739.28590478.920000.626203.612402.14850HepG2XRCC5
DTX3LENSG00000163840.51114.56480650.060900.777709.297107.10740K562ABCF1
DTX3LENSG00000163840.5306.68110508.84720-0.730507.789406.90550K562AGGF1
DTX3LENSG00000163840.5436.54760559.08820-0.356902.259601.38400K562AKAP8
DTX3LENSG00000163840.5327.05560529.46430-0.695006.111405.11490K562AKAP8L
DTX3LENSG00000163840.5412.17400608.68440-0.562403.987802.45290K562APOBEC3C
DTX3LENSG00000163840.5797.97350516.970900.626205.290704.52440K562AQR
DTX3LENSG00000163840.5295.18630428.47590-0.537603.940802.31980K562BCCIP
DTX3LENSG00000163840.5833.56180380.456301.1315014.9481012.87860K562BOP1
DTX3LENSG00000163840.5292.16440188.597900.631403.379402.18980K562CCAR1
DTX3LENSG00000163840.5915.02160581.412400.654103.551302.32090K562CNOT7
DTX3LENSG00000163840.5693.71050404.477000.778204.780503.75380K562CPSF6
DTX3LENSG00000163840.51400.75550847.977700.724008.827307.12700K562CELF1
DTX3LENSG00000163840.51125.25210545.713701.0439025.8579024.05850K562DDX47
DTX3LENSG00000163840.5325.29230211.128700.623503.489001.97330K562DHX30
DTX3LENSG00000163840.5449.42360569.83090-0.342502.605201.75970K562DKC1
DTX3LENSG00000163840.5475.32300338.353100.490302.590401.35490K562EEF2
DTX3LENSG00000163840.5742.18640434.253400.7731011.136309.83790K562EIF2S2
DTX3LENSG00000163840.5591.45680191.839201.6243014.2458012.00950K562EIF3A
DTX3LENSG00000163840.5539.72900350.068400.624503.952802.68880K562EIF3D
DTX3LENSG00000163840.51027.70360689.790800.575108.480806.86460K562EIF4G2
DTX3LENSG00000163840.5393.19780282.891800.474902.355701.32700K562FKBP4
DTX3LENSG00000163840.5685.90980411.656600.736503.318202.37690K562FMR1
DTX3LENSG00000163840.5635.98470348.964200.865805.944004.54980K562FTO
DTX3LENSG00000163840.5449.58070330.846500.442302.977602.35320K562FXR1
DTX3LENSG00000163840.5254.61650358.98000-0.495602.866501.40480K562G3BP1
DTX3LENSG00000163840.5569.45310373.558700.608105.937304.30670K562GLRX3
DTX3LENSG00000163840.5636.74470386.130200.721505.422304.31660K562GPKOW
DTX3LENSG00000163840.5824.91920521.690600.661003.408801.39910K562HNRNPA0
DTX3LENSG00000163840.5779.87150325.866201.2589020.2445018.71230K562HNRNPC
DTX3LENSG00000163840.5421.30080290.993500.533803.355502.08960K562HNRNPF
DTX3LENSG00000163840.5215.40720384.31430-0.835205.584804.20200K562HNRNPM
DTX3LENSG00000163840.5810.79930633.525500.355802.228601.51140K562HSPD1
DTX3LENSG00000163840.5857.11670530.764500.691303.611501.95880K562ILF2
DTX3LENSG00000163840.5323.16550197.035600.713704.288002.42410K562ILF3
DTX3LENSG00000163840.5289.46710190.431500.604003.170501.57360K562KHDRBS1
DTX3LENSG00000163840.5396.83540561.94390-0.501903.965702.95550K562KIF1C
DTX3LENSG00000163840.5544.89420329.827100.724202.775201.84040K562KRR1
DTX3LENSG00000163840.5197.89270330.49090-0.739904.693702.68070K562LIN28B
DTX3LENSG00000163840.5336.20390537.87810-0.677905.662303.93640K562MAK16
DTX3LENSG00000163840.5367.32680629.51220-0.777208.264406.52360K562MBNL1
DTX3LENSG00000163840.51000.97710735.276300.445003.920302.57940K562MSI2
DTX3LENSG00000163840.5550.80330392.741800.487903.660902.74120K562MTPAP
DTX3LENSG00000163840.5275.49850441.23800-0.679503.745502.67910K562NAA15
DTX3LENSG00000163840.5726.11190436.407600.7344011.4971010.11810K562NSUN2
DTX3LENSG00000163840.5864.84190624.722100.469103.135802.24970K562PCBP3
DTX3LENSG00000163840.5281.72680440.26950-0.644104.405902.35460K562PKM
DTX3LENSG00000163840.5622.63240479.173700.377702.175601.46550K562POLR2G
DTX3LENSG00000163840.5776.73770517.290900.586403.327301.34640K562PPIL4
DTX3LENSG00000163840.5201.36410292.17170-0.537002.747601.84660K562PSIP1
DTX3LENSG00000163840.51054.28200752.636300.486105.023803.92540K562PUF60
DTX3LENSG00000163840.51149.56100800.387300.522206.599604.88930K562PUM1
DTX3LENSG00000163840.51042.59110784.383900.410404.788703.51460K562PUM2
DTX3LENSG00000163840.5304.22270525.18530-0.787706.632705.83390K562PUS1
DTX3LENSG00000163840.5299.91140511.62940-0.770607.995507.01860K562RBM15
DTX3LENSG00000163840.5193.86960280.06700-0.530702.657801.35780K562RBM25
DTX3LENSG00000163840.5386.13840266.561500.534503.354002.26250K562RCC2
DTX3LENSG00000163840.5689.22450324.079801.0885011.343609.65940K562RPS19
DTX3LENSG00000163840.5859.26690518.629200.728304.479302.42420K562RPS3A
DTX3LENSG00000163840.5506.08390325.304900.637503.581302.05320K562RRP9
DTX3LENSG00000163840.5586.55950426.985200.458003.187102.02600K562SAFB
DTX3LENSG00000163840.5618.44460367.390300.751203.376402.30130K562SF3B1
DTX3LENSG00000163840.5193.33180307.00710-0.667204.447303.35340K562SF3B4
DTX3LENSG00000163840.5301.01400207.733300.535002.691101.44620K562SLBP
DTX3LENSG00000163840.5485.23490308.061000.655404.358403.05860K562SUPV3L1
DTX3LENSG00000163840.5436.46480281.021200.635104.048902.90120K562TIAL1
DTX3LENSG00000163840.51121.85840848.446900.402903.905902.23030K562UBE2L3
DTX3LENSG00000163840.5514.77150326.028400.658804.870903.47990K562UCHL5
DTX3LENSG00000163840.5623.11240462.729300.429203.803902.97400K562UPF1
DTX3LENSG00000163840.5753.98810518.521000.540003.709202.30760K562UTP3
DTX3LENSG00000163840.5551.64800395.947500.478303.518602.53330K562WDR3
DTX3LENSG00000163840.5568.79310411.707400.466204.413703.36270K562WDR43
DTX3LENSG00000163840.51069.67570582.376200.8771011.478309.57710K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for DTX3L is not available on ENCORE database.





1 RBPs can affect the splicing of DTX3L :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
MXEDTX3LENSG00000163840.5chr3+122287335122287455122289301122289382122284705122284917122290524122294050-0.460000.001080.038852includedHepG2SF3A3

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for DTX3L is not avaliable on ENCORE database.