ATIC

General Information

Gene Name : ATIC
Gene ID : ENSG00000138363.14
Essential Gene : Yes

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: ATIC)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	ATIC	ENSG00000138363.14	230.75	237.13	233.94	ENCSR000AEF
HepG2	ATIC	ENSG00000138363.14	408.40	391.89	400.14	ENCSR985KAT
K562	ATIC	ENSG00000138363.14	277.65	286.61	282.13	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for ATIC is not avaliable on ENCORE database.

Proteins bound to RNA

ATIC RNA is bound by 28 proteins.

CanvasJS.com

eCLIP assay for ATIC is not avaliable on ENCORE database.

28 proteins are bound to ATIC RNA:

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Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr2	216214381	216214457	+	3'-UTR	6.39313	55.45940	HepG2	SUB1
chr2	216211831	216211953	+	intron-Distal	3.89584	31.55985	HepG2	U2AF2
chr2	216213795	216213835	+	3'-UTR,CDS,intron-Proximal	3.60882	20.15473	HepG2	U2AF2
chr2	216213813	216213897	+	3'-UTR,CDS,intron-Proximal	3.75375	17.70298	HepG2	BCLAF1
chr2	216209554	216209589	+	3'-UTR,CDS	3.89846	16.93987	K562	YBX3
chr2	216200759	216200820	+	3'-UTR,CDS	3.20385	16.19680	HepG2	BCLAF1
chr2	216209502	216209554	+	3'-UTR,CDS	3.86788	14.72501	K562	YBX3
chr2	216211436	216211487	+	3'-UTR,CDS,intron-Proximal	3.41199	14.66482	HepG2	SF3A3
chr2	216211953	216212018	+	intron-Distal	3.60749	13.82678	HepG2	U2AF2
chr2	216213807	216213896	+	3'-UTR,CDS,intron-Proximal	3.21437	12.84576	HepG2	PPIG
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 94 entries

eCLIP assay for ATIC is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for ATIC is not available on ENCORE database.
118 RBPs can affect the levels of ATIC.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for ATIC is not available on ENCORE database.

118 RBPs can affect the gene expression of ATIC :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
ATIC	ENSG00000138363.10	1964.45570	5892.22550	-1.58470	129.01670	126.94670	HepG2	SSB
ATIC	ENSG00000138363.10	1317.86180	4443.23790	-1.75340	76.14530	73.20280	K562	HNRNPC
ATIC	ENSG00000138363.10	2411.96550	7517.13350	-1.64000	60.41400	58.03160	K562	AQR
ATIC	ENSG00000138363.10	1352.59400	3808.86070	-1.49360	33.53790	31.68750	HepG2	SUPV3L1
ATIC	ENSG00000138363.10	1579.16990	3555.96420	-1.17110	32.33840	30.59420	HepG2	HNRNPA1
ATIC	ENSG00000138363.10	3632.87450	6195.15930	-0.77000	27.04510	25.19540	K562	EIF2S2
ATIC	ENSG00000138363.10	1886.33520	3955.33600	-1.06820	26.92840	25.04050	HepG2	HNRNPC
ATIC	ENSG00000138363.10	2198.45090	3522.52270	-0.68010	24.86560	23.36100	HepG2	PUS1
ATIC	ENSG00000138363.10	2122.41470	3818.00210	-0.84710	22.98310	21.80340	HepG2	TIAL1
ATIC	ENSG00000138363.10	3139.31230	4875.12860	-0.63500	21.33130	19.73280	HepG2	SRSF7
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 162 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for ATIC is not available on ENCORE database.

5 RBPs can affect the splicing of ATIC :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
MXE	ATIC	ENSG00000138363.10	chr2	+	216189963	216190052	216190709	216190861	216184387	216184454	216191544	216191701	-0.09800	0.00006	0.00492	2included	K562	LIN28B
MXE	ATIC	ENSG00000138363.10	chr2	+	216190709	216190861	216191544	216191701	216189963	216190052	216197104	216197230	-0.11800	0.00017	0.00903	2included	HepG2	XRN2
MXE	ATIC	ENSG00000138363.10	chr2	+	216182879	216182956	216184387	216184454	216176813	216177347	216189963	216190052	0.10100	0.00053	0.01602	1included	HepG2	DDX55
MXE	ATIC	ENSG00000138363.10	chr2	+	216190709	216190861	216191544	216191701	216189963	216190052	216197104	216197230	-0.09000	0.00301	0.08705	2included	HepG2	BCCIP
MXE	ATIC	ENSG00000138363.10	chr2	+	216190709	216190861	216191544	216191701	216189963	216190052	216197104	216197230	0.08800	0.00961	0.05219	1included	HepG2	U2AF2

Showing 1 to 5 of 5 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

ATIC

General Information

Functions

Localization

Domains (AlphaFold: ATIC)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for ATIC is not avaliable on ENCORE database.

28 proteins are bound to ATIC RNA:

eCLIP assay for ATIC is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for ATIC is not available on ENCORE database.

118 RBPs can affect the gene expression of ATIC :

The Knockdown/knockout RNA-Seq assay for ATIC is not available on ENCORE database.

5 RBPs can affect the splicing of ATIC :

The Knockdown/knockout RNA-Seq assay for ATIC is not avaliable on ENCORE database.