SEMA6B

General Information

Gene Name       : SEMA6B
Gene ID             : ENSG00000167680.15
Essential Gene : No

Functions

Localization

Domains (AlphaFold: SEMA6B)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878SEMA6BENSG00000167680.150.000.000.00ENCSR000AEF
HepG2SEMA6BENSG00000167680.15112.0426.2769.16ENCSR985KAT
K562SEMA6BENSG00000167680.151.950.971.46ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for SEMA6B is not avaliable on ENCORE database.



Proteins bound to RNA
  • SEMA6B RNA is bound by 19 proteins.  







eCLIP assay for SEMA6B is not avaliable on ENCORE database.





19 proteins are bound to SEMA6B RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr1945432404543331-3'-UTR,intron-Distal3.5024222.35198HepG2LARP4
chr1945429094542922-3'-UTR,intron-Distal,intron-Proximal3.618507.80855HepG2DDX3X
chr1945429684543035-3'-UTR,CDS,intron-Distal4.5771715.14578HepG2UPF1
chr1945430094543156-3'-UTR,CDS,intron-Distal3.3651340.48689HepG2DDX55
chr1945432414543317-3'-UTR,intron-Distal3.3339724.96011HepG2DDX55
chr1945428274542920-3'-UTR,intron-Distal,intron-Proximal3.087145.00913HepG2LIN28B
chr1945432244543316-3'-UTR,intron-Distal4.1922715.60686HepG2UPF1
chr1945426164542668-3'-UTR,intron-Distal3.118768.63173HepG2PCBP2
chr1945429564543029-3'-UTR,CDS,intron-Distal3.0775319.82539HepG2DDX3X
chr1945435044543611-3'-UTR,intron-Distal3.611149.45928HepG2UPF1
chr1945430354543167-3'-UTR,CDS,intron-Distal4.4021931.58727HepG2UPF1
chr1945584264558495-5'-UTR,CDS,intron-Distal,intron-Proximal3.2447629.56729HepG2DDX3X
chr1945464314546531-CDS,intron-Distal,intron-Proximal3.401034.20336HepG2AQR
chr1945484094548476-CDS,intron-Distal,intron-Proximal3.618724.57180HepG2AQR
chr1945442704544336-CDS,intron-Distal,intron-Proximal4.306219.22287HepG2UPF1
chr1945543484554409-CDS,intron-Distal,intron-Proximal3.166989.10951HepG2PRPF8
chr1945570174557093-CDS,intron-Distal,intron-Proximal4.958408.42614HepG2EFTUD2
chr1945526274552705-CDS,intron-Distal,intron-Proximal5.069205.40008K562SF3B4
chr1945580924558157-CDS,intron-Distal4.1778831.24326HepG2DDX3X
chr1945480004548042-CDS,intron-Distal,intron-Proximal3.493243.67894HepG2AQR
chr1945569164556964-CDS,intron-Distal,intron-Proximal5.7512913.18741HepG2PRPF8
chr1945569704557023-CDS,intron-Distal3.292207.61685HepG2PPIG
chr1945526264552648-CDS,intron-Distal3.6885910.03874HepG2DDX3X
chr1945544044554412-CDS,intron-Distal3.638793.45072HepG2YBX3
chr1945439884544066-CDS,intron-Distal3.667137.66875HepG2PCBP2
chr1945554354555515-CDS,intron-Distal,intron-Proximal4.6592516.53416HepG2PRPF8
chr1945583814558426-CDS,intron-Distal3.0708831.97265HepG2DDX3X
chr1945538554553934-intron-Distal7.5035834.83989K562AGGF1
chr1945531324553204-intron-Distal7.3238938.59595K562AGGF1
chr1945532044553336-intron-Distal5.4633322.84712HepG2XPO5
chr1945536774553729-intron-Distal5.3620716.16627HepG2AGGF1
chr1945536164553677-intron-Distal6.0233427.22835HepG2AGGF1
chr1945532474553299-intron-Distal3.738364.80250HepG2CDC40
chr1945540364554067-intron-Distal6.3398914.30686K562AGGF1
chr1945537894553850-intron-Distal5.2378716.68855HepG2AGGF1
chr1945479604547995-intron-Distal,intron-Proximal4.124753.59236HepG2AQR
chr1945536414553725-intron-Distal3.506033.15679HepG2CDC40
chr1945534174553479-intron-Distal6.9043619.87451K562AGGF1
chr1945540544554118-intron-Distal4.123257.49381HepG2PCBP2
chr1945538504553936-intron-Distal5.9795626.75911HepG2AGGF1
chr1945535454553666-intron-Distal5.6387613.42410HepG2GTF2F1
chr1945479684548038-intron-Distal,intron-Proximal3.831154.89208K562AQR
chr1945530424553188-intron-Distal3.882605.32768K562YBX3
chr1945532154553304-intron-Distal4.038303.65750K562YBX3
chr1945479424548003-intron-Distal,intron-Proximal4.071406.10859HepG2EFTUD2
chr1945530374553123-intron-Distal3.588659.46102HepG2XPO5
chr1945536444553720-intron-Distal4.2819711.01721HepG2HNRNPL
chr1945532284553320-intron-Distal3.6384611.04448HepG2HNRNPL
chr1945532444553330-intron-Distal4.232517.18225HepG2GTF2F1
chr1945551914555281-intron-Distal,intron-Proximal6.2765224.80222HepG2EFTUD2
chr1945535314553644-intron-Distal3.6798513.05821HepG2HNRNPL
chr1945539034553956-intron-Distal4.500985.54349HepG2GTF2F1
chr1945574944557531-intron-Distal3.866353.19526HepG2CSTF2T
chr1945479404548000-intron-Distal,intron-Proximal3.221008.04193HepG2PRPF8
chr1945538464554030-intron-Distal4.2117215.95273HepG2HNRNPL
chr1945477044547800-intron-Distal6.3990814.81270HepG2EFTUD2
chr1945527694552803-intron-Distal5.438876.34931HepG2XPO5
chr1945535754553680-intron-Distal7.0056421.75258HepG2XPO5
chr1945531974553305-intron-Distal4.270933.59673K562HNRNPL
chr1945536844553727-intron-Distal4.329604.70962HepG2GTF2F1
chr1945540124554099-intron-Distal3.992745.76648HepG2AGGF1
chr1945534184553485-intron-Distal4.6175715.96698HepG2AGGF1
chr1945533404553400-intron-Distal7.0335222.20403K562AGGF1
chr1945523714552434-intron-Distal,intron-Proximal4.406474.28193HepG2AQR
chr1945532214553339-intron-Distal5.4210735.34573HepG2AGGF1
chr1945480004548037-intron-Distal,intron-Proximal3.712747.85990HepG2PRPF8
chr1945542404554322-intron-Distal,intron-Proximal3.055193.63795HepG2RBFOX2
chr1945536674553730-intron-Distal7.2779226.87471K562AGGF1
chr1945535374553616-intron-Distal5.5265328.58681HepG2AGGF1
chr1945533394553395-intron-Distal4.3688213.93590HepG2AGGF1
chr1945539364554012-intron-Distal4.9938515.70831HepG2AGGF1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for SEMA6B is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for SEMA6B is not available on ENCORE database.

  • 106 RBPs can affect the levels of SEMA6B.  








The Knockdown/knockout RNA-Seq assay for SEMA6B is not available on ENCORE database.





106 RBPs can affect the gene expression of SEMA6B :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
SEMA6BENSG00000167680.113485.439702716.163800.359707.652506.74360HepG2ACO1
SEMA6BENSG00000167680.111439.631802363.53870-0.715202.234601.75170HepG2AKAP1
SEMA6BENSG00000167680.111127.754901955.41590-0.794002.790302.00290HepG2ASCC1
SEMA6BENSG00000167680.111142.117702043.03990-0.839005.270604.47760HepG2BOP1
SEMA6BENSG00000167680.11838.243001638.50280-0.9669015.1600013.60880HepG2CALR
SEMA6BENSG00000167680.114824.102603102.609400.636705.978204.51420HepG2CCAR1
SEMA6BENSG00000167680.111111.142101875.53110-0.755304.608003.74060HepG2CPSF6
SEMA6BENSG00000167680.112154.872801516.829100.506409.293508.06210HepG2DAZAP1
SEMA6BENSG00000167680.11702.619001214.15670-0.789102.183601.38260HepG2DDX24
SEMA6BENSG00000167680.111953.994901332.637400.552007.212805.18110HepG2DDX52
SEMA6BENSG00000167680.111341.418002133.56160-0.669504.927003.60280HepG2DDX5
SEMA6BENSG00000167680.113402.770101945.587900.806402.479501.89280HepG2DDX6
SEMA6BENSG00000167680.11648.02030976.77580-0.592003.462502.37150HepG2DHX30
SEMA6BENSG00000167680.112144.614702598.52900-0.277003.535302.78480HepG2DKC1
SEMA6BENSG00000167680.11803.421901012.71230-0.334002.298901.65200HepG2DNAJC21
SEMA6BENSG00000167680.111508.108801003.836100.5871010.540709.36570HepG2DNAJC2
SEMA6BENSG00000167680.11515.423501142.33580-1.148202.994701.83490HepG2AGO1
SEMA6BENSG00000167680.11537.117901496.54890-1.4783052.3140049.63710HepG2EIF4G1
SEMA6BENSG00000167680.112020.933402686.64160-0.410802.465901.43490HepG2ESF1
SEMA6BENSG00000167680.112982.172104109.93740-0.462805.182004.40570HepG2ETF1
SEMA6BENSG00000167680.11538.005801181.44880-1.134903.534302.26600HepG2FASTKD2
SEMA6BENSG00000167680.11662.624401878.93470-1.503707.488905.82710HepG2FTO
SEMA6BENSG00000167680.111504.418302082.79980-0.469305.681604.56690HepG2FUBP3
SEMA6BENSG00000167680.114064.793902085.312900.9628010.721809.44690HepG2FXR1
SEMA6BENSG00000167680.111035.359701933.60730-0.901203.341602.61530HepG2G3BP1
SEMA6BENSG00000167680.111185.597402125.81180-0.842405.268404.40340HepG2GPKOW
SEMA6BENSG00000167680.11309.248101109.65910-1.843302.791601.41760HepG2HLTF
SEMA6BENSG00000167680.111950.247001381.678700.4971012.3387011.00910HepG2HNRNPL
SEMA6BENSG00000167680.111436.588302028.72390-0.497902.544101.93640HepG2HNRNPLL
SEMA6BENSG00000167680.111590.489001129.749300.493403.153302.50960HepG2HNRNPU
SEMA6BENSG00000167680.111420.63290843.520500.751902.411601.31540HepG2KHDRBS1
SEMA6BENSG00000167680.117168.755703277.927901.1288017.8676015.77110HepG2LARP4
SEMA6BENSG00000167680.111781.278102534.03240-0.508504.247403.25620HepG2MSI2
SEMA6BENSG00000167680.112730.734301504.091100.860307.981206.70730HepG2NOL12
SEMA6BENSG00000167680.111274.48010725.132000.813506.242504.09760HepG2NOLC1
SEMA6BENSG00000167680.113303.621801311.693001.332509.636807.56750HepG2NONO
SEMA6BENSG00000167680.11970.118701799.03240-0.891005.674204.62350HepG2NSUN2
SEMA6BENSG00000167680.111510.359202082.75450-0.463604.919102.80640HepG2NUP35
SEMA6BENSG00000167680.111075.186101910.79310-0.829602.982702.23540HepG2PABPC4
SEMA6BENSG00000167680.111470.242201118.230800.394704.404503.36580HepG2PARN
SEMA6BENSG00000167680.111849.058201007.642200.8757022.4715020.52440HepG2PPIL4
SEMA6BENSG00000167680.111802.900802250.26760-0.319803.115202.29950HepG2PRPF4
SEMA6BENSG00000167680.112131.692401435.820000.570008.058007.11240HepG2PUF60
SEMA6BENSG00000167680.112110.749001524.225400.4696012.1718011.11440HepG2PUM1
SEMA6BENSG00000167680.112215.641302766.53030-0.320403.617902.93310HepG2PUS1
SEMA6BENSG00000167680.111395.318102283.04840-0.710405.939205.07210HepG2QKI
SEMA6BENSG00000167680.112140.075103362.83500-0.652003.144402.23590HepG2RBM15
SEMA6BENSG00000167680.111572.578703435.08170-1.1272022.8628021.66460HepG2RBM22
SEMA6BENSG00000167680.111679.067702441.05800-0.539801.919301.33800HepG2RPLP0
SEMA6BENSG00000167680.111880.281601255.698000.582408.000707.01810HepG2RPS19
SEMA6BENSG00000167680.111592.411501006.078700.662408.155207.13610HepG2SAFB2
SEMA6BENSG00000167680.114050.783002730.077700.569204.762703.86340HepG2SF3A3
SEMA6BENSG00000167680.111211.923102007.89230-0.728404.597903.70600HepG2SF3B1
SEMA6BENSG00000167680.111900.974801376.807700.465304.914204.02050HepG2SLBP
SEMA6BENSG00000167680.112178.891701173.235900.8930037.0786035.19640HepG2SMN1
SEMA6BENSG00000167680.11500.248302234.18370-2.1590017.2182015.31180HepG2SNRNP70
SEMA6BENSG00000167680.111888.916403879.68280-1.0384022.0651021.00360HepG2SRFBP1
SEMA6BENSG00000167680.111906.022502290.97890-0.265401.912501.49880HepG2SRSF1
SEMA6BENSG00000167680.112811.060701417.709900.9875039.7713037.78520HepG2SRSF5
SEMA6BENSG00000167680.11867.549901863.93100-1.1033019.2596018.04650HepG2SRSF9
SEMA6BENSG00000167680.112551.297503368.28130-0.400804.920504.27420HepG2SSB
SEMA6BENSG00000167680.111297.212702091.20530-0.688904.853903.25990HepG2STAU1
SEMA6BENSG00000167680.112921.696301612.286600.8576037.4418035.61360HepG2SUCLG1
SEMA6BENSG00000167680.11369.276301420.42700-1.943604.899904.03900HepG2SUPV3L1
SEMA6BENSG00000167680.11831.760602059.53570-1.3081015.4858014.32060HepG2TAF15
SEMA6BENSG00000167680.111864.498301097.679800.764207.730606.97210HepG2TIAL1
SEMA6BENSG00000167680.111993.893901402.799100.507204.187403.08490HepG2TUFM
SEMA6BENSG00000167680.111946.679402678.91080-0.460602.982102.33040HepG2U2AF1
SEMA6BENSG00000167680.112365.811201484.882700.671902.661101.84000HepG2UBE2L3
SEMA6BENSG00000167680.111368.614502220.65650-0.6983022.1901020.61870HepG2ZC3H8
SEMA6BENSG00000167680.111677.535002662.81270-0.6666020.8530019.69420HepG2ZNF622
SEMA6BENSG00000167680.11460.63890121.400701.9238033.8524031.94130K562AGGF1
SEMA6BENSG00000167680.11227.77040133.403500.771704.351403.05730K562AKAP8
SEMA6BENSG00000167680.11435.36770126.323501.785009.988708.64760K562AKAP8L
SEMA6BENSG00000167680.1146.15550124.43010-1.430805.357804.58750K562AQR
SEMA6BENSG00000167680.11235.35550132.544900.828305.435504.10310K562ATP5C1
SEMA6BENSG00000167680.1188.3627042.974001.039902.668101.38660K562BCCIP
SEMA6BENSG00000167680.11110.1444041.510501.407706.161704.70850K562BCLAF1
SEMA6BENSG00000167680.11125.4177031.491801.993605.969104.33670K562CSTF2
SEMA6BENSG00000167680.11316.57230142.436301.152107.963605.53110K562DDX19B
SEMA6BENSG00000167680.1164.00170129.88630-1.021104.749803.92920K562DDX47
SEMA6BENSG00000167680.11252.19730142.510300.823404.356502.59950K562DDX6
SEMA6BENSG00000167680.11221.06150135.929400.701503.990002.91280K562DKC1
SEMA6BENSG00000167680.1132.9287078.95700-1.261702.839301.82120K562EIF3A
SEMA6BENSG00000167680.11112.1587061.383700.869503.108901.76250K562EXOSC5
SEMA6BENSG00000167680.1129.22400152.71390-2.3856017.2436015.84570K562FXR1
SEMA6BENSG00000167680.116.6662034.66310-2.378504.228203.31240K562G3BP2
SEMA6BENSG00000167680.11176.9947093.248200.924504.150003.43400K562HNRNPC
SEMA6BENSG00000167680.11250.14890183.124000.449902.154201.36680K562HNRNPU
SEMA6BENSG00000167680.11172.8843077.418401.159005.445203.79800K562IGF2BP2
SEMA6BENSG00000167680.11167.2542078.712801.087306.270304.36450K562IGF2BP3
SEMA6BENSG00000167680.11242.30270134.058700.853805.071803.88910K562KIF1C
SEMA6BENSG00000167680.11205.78680128.328900.681202.933601.81910K562MAK16
SEMA6BENSG00000167680.11415.77220150.179901.4690018.8403016.20850K562MBNL1
SEMA6BENSG00000167680.11178.49210105.265400.761702.690901.82170K562NAA15
SEMA6BENSG00000167680.11114.2576045.739901.320704.777702.94030K562NONO
SEMA6BENSG00000167680.11169.3569083.147801.026203.215002.12580K562PABPN1
SEMA6BENSG00000167680.1199.0388040.503201.289904.867903.73330K562PPIG
SEMA6BENSG00000167680.11189.8972098.878200.941402.904101.40460K562PPP1R8
SEMA6BENSG00000167680.11252.2112083.616601.5927012.5800010.37470K562PSIP1
SEMA6BENSG00000167680.11118.8663078.978600.589701.897101.32820K562PTBP1
SEMA6BENSG00000167680.1188.17070169.35210-0.941702.825102.00030K562PUF60
SEMA6BENSG00000167680.1188.30500180.24660-1.029403.377602.19370K562PUM1
SEMA6BENSG00000167680.11196.13230125.274000.646602.620302.08840K562PUS1
SEMA6BENSG00000167680.11298.62690122.064201.2906012.3331011.08530K562RBM15
SEMA6BENSG00000167680.11122.8017072.360200.763002.407501.46760K562SRFBP1
SEMA6BENSG00000167680.11123.0758073.152900.750502.662001.63620K562SRSF5
SEMA6BENSG00000167680.1123.9260060.07390-1.328202.628301.83080K562SYNCRIP
SEMA6BENSG00000167680.11176.8249078.349301.174205.773204.72840K562TARDBP
SEMA6BENSG00000167680.11173.4894075.581801.198604.596203.50060K562TIA1
SEMA6BENSG00000167680.1194.2783041.750901.175003.772202.08150K562TRIP6
SEMA6BENSG00000167680.11273.07100163.699400.738104.756103.08620K562TROVE2
SEMA6BENSG00000167680.118.8286034.67020-1.973403.616002.69610K562U2AF2
SEMA6BENSG00000167680.11101.0884046.188201.129903.466802.31980K562UCHL5
SEMA6BENSG00000167680.11277.85910127.019101.129205.566403.54240K562UTP18
SEMA6BENSG00000167680.1150.82290113.15690-1.154803.732301.82090K562XRCC6
SEMA6BENSG00000167680.11104.0351047.065501.144203.739702.25870K562XRN2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for SEMA6B is not available on ENCORE database.





2 RBPs can affect the splicing of SEMA6B :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
A3SSSEMA6BENSG00000167680.11chr19-4554987455516245549874555068455548545555760.066000.001250.03214longerHepG2U2AF2
A3SSSEMA6BENSG00000167680.11chr19-4558037455819645580374558161455834845584690.055000.002190.07588longerHepG2U2AF1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for SEMA6B is not avaliable on ENCORE database.