SEC63

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	SEC63	ENSG00000025796.13	33.57	27.25	30.41	ENCSR000AEF
HepG2	SEC63	ENSG00000025796.13	18.58	39.38	28.98	ENCSR985KAT
K562	SEC63	ENSG00000025796.13	26.92	29.57	28.25	ENCSR000AEO

Assay Type	Exp_Name	ENCODE ID	Target label	Biosample	Status	Linked Antibody	Controls	Method	Note
knockdown followed by RNA-seq	SEC63-BGKcLV33-K562	ENCSR082BCP	SEC63	K562	Released		ENCSR271ZAB	CRISPR	KD% = 0.0,0.0
knockdown followed by RNA-seq	SEC63-BGHcLV31-HepG2	ENCSR981TQN	SEC63	HepG2	Released		ENCSR452TFV	CRISPR	KD% = 50.9,51.0

GeneName	Antibody_DCC_ID	Product_ID	Lot_ID	Phosphate	HepG2 Primary Validation	K562 Primary Validation	HepG2 Secondary Validation	K562 Secondary Validation
SEC63	ENCAB877MEL	A305-084A	1				BGHcLV31-37, Released, ENCODE4	BGKcLV33-41, Released, ENCODE4

GeneName	Cell_Line	Method	Exp_ID	Control_ID	Sample_reps	Control_reps	KD%	Status	Project
SEC63	K562	CRISPR			BGKcLV33-35,BGKcLV33-36	BGKcLV33-1,BGKcLV33-2	74.7,72.1	NotSatisfied	ENCODE4
SEC63	K562	CRISPR	ENCSR082BCP	ENCSR271ZAB	SEC63-BGKcLV33-41,SEC63-BGKcLV33-42	NT-BGKcLV33-1,NT-BGKcLV33-2	0.0,0.0	Released	ENCODE4
SEC63	HepG2	CRISPR	ENCSR981TQN	ENCSR452TFV	SEC63-BGHcLV31-37,SEC63-BGHcLV31-38	NT-BGHcLV31-1,NT-BGHcLV31-2	50.9,51.0	Released	ENCODE4

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for SEC63 is not avaliable on ENCORE database.

Proteins bound to RNA

SEC63 RNA is bound by 34 proteins.

eCLIP assay for SEC63 is not avaliable on ENCORE database.

34 proteins are bound to SEC63 RNA:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr6	108192398	108192436	-	3'-UTR,intron-Distal	5.36646	10.26259	HepG2	LIN28B
chr6	108192735	108192780	-	3'-UTR,intron-Distal	3.47164	10.92329	HepG2	BCLAF1
chr6	108192868	108192949	-	3'-UTR,CDS,intron-Distal	4.21457	14.76848	K562	ZNF622
chr6	108192866	108192994	-	3'-UTR,CDS,intron-Distal	3.89140	8.61004	K562	SRSF1
chr6	108192579	108192648	-	3'-UTR,intron-Distal	3.93308	7.71112	HepG2	LIN28B
chr6	108192579	108192650	-	3'-UTR,intron-Distal	5.50078	10.97206	K562	LIN28B
chr6	108192729	108192769	-	3'-UTR,intron-Distal	3.12603	3.96176	HepG2	LIN28B
chr6	108191894	108191963	-	3'-UTR,intron-Distal,intron-Proximal	3.49129	3.84340	K562	CSTF2T
chr6	108191874	108191972	-	3'-UTR,intron-Distal,intron-Proximal,polyA_site	3.74555	7.08613	HepG2	CSTF2
chr6	108192196	108192305	-	3'-UTR,intron-Distal	3.39908	5.55412	K562	IGF2BP1
chr6	108250618	108250654	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.34623	6.91872	HepG2	BCLAF1
chr6	108246059	108246089	-	3'-UTR,CDS,intron-Distal	5.30535	7.04013	HepG2	BCLAF1
chr6	108189732	108189790	-	3'-UTR,intron-Distal	4.47973	8.16255	K562	TIA1
chr6	108192869	108193036	-	3'-UTR,CDS,intron-Distal	4.53994	32.95711	K562	UCHL5
chr6	108192852	108192971	-	3'-UTR,CDS,intron-Distal	4.64498	26.33101	HepG2	BCLAF1
chr6	108192891	108192999	-	3'-UTR,CDS,intron-Distal	3.89985	10.33175	HepG2	TRA2A
chr6	108192387	108192446	-	3'-UTR,intron-Distal	5.40205	10.97206	K562	LIN28B
chr6	108192734	108192766	-	3'-UTR,intron-Distal	3.73086	3.25521	K562	LIN28B
chr6	108246089	108246133	-	3'-UTR,CDS,intron-Distal	3.54117	8.16183	HepG2	BCLAF1
chr6	108192310	108192378	-	3'-UTR,intron-Distal	3.51179	3.81856	K562	IGF2BP1
chr6	108192891	108192992	-	3'-UTR,CDS,intron-Distal	3.77426	7.77892	K562	TRA2A
chr6	108279238	108279302	-	5'-UTR,intron-Distal,intron-Proximal	3.38420	6.18174	HepG2	EFTUD2
chr6	108279192	108279374	-	5'-UTR,CDS,intron-Distal,intron-Proximal	3.31376	12.37653	HepG2	PRPF4
chr6	108279185	108279340	-	5'-UTR,CDS,intron-Distal,intron-Proximal	3.20242	34.28419	HepG2	DDX3X
chr6	108243000	108243074	-	CDS,intron-Distal,intron-Proximal	4.29357	16.95425	HepG2	BCLAF1
chr6	108279182	108279197	-	CDS,intron-Distal,intron-Proximal	4.64147	6.76307	K562	LIN28B
chr6	108204241	108204318	-	CDS,intron-Distal,intron-Proximal	4.85026	5.29009	HepG2	TRA2A
chr6	108232512	108232570	-	CDS,intron-Distal,intron-Proximal	3.86035	3.02234	K562	KHSRP
chr6	108225861	108225901	-	CDS,intron-Distal	3.11707	5.99226	K562	YBX3
chr6	108202394	108202429	-	CDS,intron-Distal	3.98723	11.60362	HepG2	BCLAF1
chr6	108225832	108225860	-	CDS,intron-Distal,intron-Proximal	3.45135	8.79436	K562	YBX3
chr6	108234601	108234685	-	CDS,intron-Distal,intron-Proximal	3.10439	6.94390	K562	SF3B4
chr6	108225830	108225901	-	CDS,intron-Distal,intron-Proximal	4.23288	25.79765	HepG2	BCLAF1
chr6	108233884	108233978	-	CDS,intron-Distal,intron-Proximal	4.84878	6.69228	HepG2	PRPF8
chr6	108230189	108230250	-	CDS,intron-Distal,intron-Proximal	3.12471	4.62757	K562	SF3B4
chr6	108233925	108233979	-	CDS,intron-Distal,intron-Proximal	4.44584	12.18291	HepG2	PPIG
chr6	108230177	108230240	-	CDS,intron-Distal,intron-Proximal	3.47613	4.24070	HepG2	GRWD1
chr6	108279042	108279116	-	CDS,intron-Distal	3.44203	13.63393	HepG2	PRPF8
chr6	108279061	108279168	-	CDS,intron-Distal,intron-Proximal	3.37547	9.47203	HepG2	GRWD1
chr6	108243079	108243110	-	CDS,intron-Distal	4.29779	10.72049	K562	U2AF2
chr6	108233933	108234025	-	CDS,intron-Distal,intron-Proximal	3.86747	5.30069	HepG2	AQR
chr6	108234569	108234626	-	CDS,intron-Distal,intron-Proximal	3.15233	8.20368	K562	ZNF622
chr6	108197766	108197809	-	CDS,intron-Distal,intron-Proximal	3.52190	14.59078	HepG2	BCLAF1
chr6	108202396	108202452	-	CDS,intron-Distal	4.96049	5.44793	K562	ZNF622
chr6	108234569	108234611	-	CDS,intron-Distal,intron-Proximal	3.26162	9.00189	HepG2	BCLAF1
chr6	108279125	108279182	-	CDS,intron-Distal,intron-Proximal	4.46887	9.97366	K562	LIN28B
chr6	108215066	108215119	-	CDS,intron-Distal,intron-Proximal	5.61409	14.73127	K562	U2AF2
chr6	108232496	108232567	-	CDS,intron-Distal,intron-Proximal	4.33777	4.54206	HepG2	PRPF8
chr6	108232545	108232585	-	CDS,intron-Distal,intron-Proximal	4.20368	4.23351	K562	BUD13
chr6	108224179	108224202	-	CDS,intron-Distal,intron-Proximal	3.96663	7.23562	HepG2	BCLAF1
chr6	108225831	108225887	-	CDS,intron-Distal,intron-Proximal	3.79658	8.48086	K562	UCHL5
chr6	108194088	108194116	-	CDS,intron-Distal,intron-Proximal	3.12320	7.10293	HepG2	BCLAF1
chr6	108202251	108202356	-	CDS,intron-Distal,intron-Proximal	3.88889	9.41329	K562	AQR
chr6	108233944	108233979	-	CDS,intron-Distal,intron-Proximal	3.28766	4.44630	K562	ZNF622
chr6	108214725	108214777	-	CDS,intron-Distal,intron-Proximal	3.37600	3.67894	HepG2	AQR
chr6	108243110	108243129	-	CDS,intron-Distal,intron-Proximal	4.27720	10.51303	K562	U2AF2
chr6	108215066	108215119	-	CDS,intron-Distal,intron-Proximal	3.14546	8.39734	HepG2	U2AF2
chr6	108204227	108204320	-	CDS,intron-Distal,intron-Proximal	6.61875	20.03336	HepG2	BCLAF1
chr6	108225901	108225926	-	CDS,intron-Distal,intron-Proximal	5.54317	19.29311	HepG2	BCLAF1
chr6	108243039	108243113	-	CDS,intron-Distal	3.75022	4.38503	K562	SND1
chr6	108204339	108204350	-	CDS,intron-Distal,intron-Proximal	3.15233	3.02345	K562	ZNF622
chr6	108214684	108214722	-	CDS,intron-Distal,intron-Proximal	3.67956	4.49887	K562	ZNF622
chr6	108243081	108243128	-	CDS,intron-Distal,intron-Proximal	3.00418	4.68360	HepG2	U2AF1
chr6	108234533	108234626	-	CDS,intron-Distal,intron-Proximal	4.25557	8.11807	HepG2	PRPF8
chr6	108225835	108225926	-	CDS,intron-Distal,intron-Proximal	3.42128	5.61495	HepG2	ZNF800
chr6	108227650	108227702	-	CDS,intron-Distal,intron-Proximal	4.04514	25.12794	HepG2	BCLAF1
chr6	108233914	108233980	-	CDS,intron-Distal,intron-Proximal	4.12363	4.89208	K562	AQR
chr6	108243074	108243114	-	CDS,intron-Distal,intron-Proximal	4.92758	9.74753	HepG2	BCLAF1
chr6	108224075	108224106	-	CDS,intron-Distal,intron-Proximal	3.58034	5.97823	HepG2	BCLAF1
chr6	108227702	108227784	-	CDS,intron-Distal	4.82434	25.32118	HepG2	BCLAF1
chr6	108222572	108222623	-	CDS,intron-Distal,intron-Proximal	3.39153	4.15543	HepG2	HLTF
chr6	108227914	108227982	-	CDS,intron-Distal,intron-Proximal	3.68234	17.92852	HepG2	BCLAF1
chr6	108242998	108243055	-	CDS,intron-Distal,intron-Proximal	3.19992	3.70435	HepG2	LIN28B
chr6	108227887	108227914	-	CDS,intron-Distal	3.28812	8.71292	HepG2	BCLAF1
chr6	108202429	108202443	-	CDS,intron-Distal	4.36707	11.11870	HepG2	BCLAF1
chr6	108215031	108215083	-	CDS,intron-Distal,intron-Proximal	3.31510	6.65384	K562	UCHL5
chr6	108222572	108222617	-	CDS,intron-Distal,intron-Proximal	4.65230	16.88216	HepG2	BCLAF1
chr6	108214806	108214862	-	CDS,intron-Distal,intron-Proximal	3.40684	6.21602	K562	ZNF622
chr6	108192949	108192999	-	CDS,intron-Distal	4.00650	9.86961	K562	ZNF622
chr6	108234568	108234601	-	CDS,intron-Distal,intron-Proximal	4.08952	10.90751	HepG2	PPIG
chr6	108225887	108225925	-	CDS,intron-Distal	3.63336	6.98424	K562	UCHL5
chr6	108204312	108204363	-	CDS,intron-Distal,intron-Proximal	3.32389	4.65237	HepG2	U2AF2
chr6	108215045	108215101	-	CDS,intron-Distal	3.54274	13.09340	HepG2	BCLAF1
chr6	108218851	108218907	-	CDS,intron-Distal,intron-Proximal	3.29758	12.80369	HepG2	BCLAF1
chr6	108222574	108222677	-	CDS,intron-Distal	4.18241	11.39909	K562	ZNF622
chr6	108215066	108215118	-	CDS,intron-Distal,intron-Proximal	4.22231	6.14698	K562	U2AF1
chr6	108218907	108218935	-	CDS,intron-Distal	3.59099	9.67260	HepG2	BCLAF1
chr6	108227675	108227692	-	CDS,intron-Distal	3.30452	6.97987	K562	ZNF622
chr6	108214814	108214856	-	CDS,intron-Distal	4.65955	9.74753	HepG2	BCLAF1
chr6	108204191	108204206	-	CDS,intron-Distal,intron-Proximal	3.33762	4.74886	HepG2	BCLAF1
chr6	108230188	108230239	-	CDS,intron-Distal,intron-Proximal	3.27813	7.61291	HepG2	BCLAF1
chr6	108230130	108230149	-	CDS,intron-Distal,intron-Proximal	3.61390	5.76104	HepG2	BCLAF1
chr6	108233926	108233978	-	CDS,intron-Distal	4.26322	15.80902	HepG2	BCLAF1
chr6	108202443	108202454	-	CDS,intron-Distal	3.72039	5.97823	HepG2	BCLAF1
chr6	108234592	108234633	-	CDS,intron-Distal,intron-Proximal	3.33611	3.20659	K562	SND1
chr6	108214801	108214885	-	CDS,intron-Distal,intron-Proximal	4.09661	9.89239	HepG2	AQR
chr6	108232549	108232577	-	CDS,intron-Distal,intron-Proximal	3.85836	6.39464	HepG2	BCLAF1
chr6	108222638	108222710	-	CDS,intron-Distal	4.56529	16.88216	HepG2	BCLAF1
chr6	108204248	108204310	-	CDS,intron-Distal	3.45963	4.33023	K562	ZNF622
chr6	108234569	108234592	-	CDS,intron-Distal,intron-Proximal	3.93671	3.24875	K562	SND1
chr6	108214688	108214765	-	CDS,intron-Distal,intron-Proximal	6.45778	18.62730	HepG2	BCLAF1
chr6	108222633	108222697	-	CDS,intron-Distal	4.17593	4.69071	HepG2	GRWD1
chr6	108278992	108279085	-	intron-Distal	3.49540	7.91517	HepG2	EFTUD2
chr6	108246146	108246303	-	intron-Distal,intron-Proximal	4.08251	11.77432	K562	KHSRP
chr6	108214209	108214289	-	intron-Distal	3.25947	3.68839	K562	KHSRP
chr6	108264812	108264867	-	intron-Distal	3.41346	3.10961	HepG2	MATR3
chr6	108232447	108232519	-	intron-Distal,intron-Proximal	5.00459	7.21051	K562	PRPF8
chr6	108206626	108206711	-	intron-Distal	4.73270	9.01206	HepG2	U2AF2
chr6	108271422	108271528	-	intron-Distal	3.48211	7.79040	K562	KHSRP
chr6	108261726	108261760	-	intron-Distal	3.60214	3.68481	HepG2	HNRNPM
chr6	108222810	108222894	-	intron-Distal,intron-Proximal	4.58620	4.96658	K562	KHSRP
chr6	108233991	108234029	-	intron-Distal,intron-Proximal	3.84547	3.60967	K562	SF3B4
chr6	108277698	108277757	-	intron-Distal	3.94118	3.34098	HepG2	HNRNPM
chr6	108218195	108218278	-	intron-Distal	4.81066	4.57427	HepG2	PCBP2
chr6	108214048	108214131	-	intron-Distal	3.59881	4.13525	K562	RBFOX2
chr6	108254635	108254696	-	intron-Distal	4.60266	5.04680	K562	HNRNPM
chr6	108278098	108278166	-	intron-Distal	3.43131	3.64762	HepG2	QKI
chr6	108265198	108265287	-	intron-Distal	4.07199	3.23532	K562	MATR3
chr6	108269007	108269080	-	intron-Distal	3.44486	3.04054	K562	GTF2F1
chr6	108277558	108277664	-	intron-Distal	3.62580	4.61500	HepG2	HNRNPM
chr6	108204476	108204563	-	intron-Distal	3.97475	6.08171	HepG2	QKI
chr6	108253072	108253161	-	intron-Distal	3.24065	3.10641	K562	HNRNPM
chr6	108218200	108218264	-	intron-Distal	4.09811	3.35169	HepG2	U2AF2
chr6	108273297	108273350	-	intron-Distal	4.40600	3.50357	HepG2	QKI
chr6	108253633	108253746	-	intron-Distal	3.30629	3.98203	K562	MATR3
chr6	108253098	108253154	-	intron-Distal	4.02141	4.28420	HepG2	HNRNPM
chr6	108265044	108265198	-	intron-Distal	3.09290	4.92339	K562	MATR3
chr6	108264741	108264815	-	intron-Distal	4.79480	4.85866	HepG2	QKI
chr6	108224448	108224541	-	intron-Distal	3.68369	4.10408	K562	KHSRP
chr6	108214474	108214546	-	intron-Distal	3.45839	5.84135	HepG2	PCBP2
chr6	108254307	108254416	-	intron-Distal	4.21785	4.49973	K562	MATR3
chr6	108272378	108272439	-	intron-Distal	3.93956	3.16986	HepG2	QKI
chr6	108214198	108214279	-	intron-Distal	4.22864	3.91772	K562	TARDBP
chr6	108271615	108271676	-	intron-Distal	3.65661	3.90822	HepG2	HNRNPM
chr6	108264974	108265085	-	intron-Distal	3.50773	4.23155	HepG2	MATR3
chr6	108211203	108211288	-	intron-Distal	4.25578	4.42734	K562	UCHL5
chr6	108277842	108277954	-	intron-Distal	3.09649	8.64089	HepG2	QKI
chr6	108206802	108206880	-	intron-Distal	3.45874	4.18806	HepG2	U2AF2
chr6	108265278	108265371	-	intron-Distal	4.72953	5.37222	HepG2	MATR3
chr6	108269007	108269077	-	intron-Distal	3.06648	3.18011	HepG2	FAM120A
chr6	108254638	108254693	-	intron-Distal	5.08714	8.33028	HepG2	HNRNPM
chr6	108268992	108269094	-	intron-Distal	4.50718	5.23978	HepG2	PRPF4
chr6	108253640	108253734	-	intron-Distal	3.51669	3.68462	HepG2	MATR3
chr6	108263948	108264035	-	intron-Distal	3.27413	3.42396	HepG2	U2AF2
chr6	108265130	108265194	-	intron-Distal	3.55146	4.61322	HepG2	MATR3
chr6	108271559	108271657	-	intron-Distal	4.08948	3.51329	HepG2	MATR3
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

eCLIP assay for SEC63 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for SEC63 is not available on ENCORE database.
100 RBPs can affect the levels of SEC63.

The Knockdown/knockout RNA-Seq assay for SEC63 is not available on ENCORE database.

100 RBPs can affect the gene expression of SEC63 :

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
SEC63	ENSG00000025796.9	2132.39360	2687.35580	-0.33370	4.82820	4.06680	HepG2	ACO1
SEC63	ENSG00000025796.9	3089.49660	2307.32050	0.42110	2.82980	1.82280	HepG2	ADAR
SEC63	ENSG00000025796.9	2627.48950	4669.79670	-0.82970	10.89250	9.90430	HepG2	AKAP1
SEC63	ENSG00000025796.9	2182.19920	2700.11670	-0.30720	4.65000	3.67590	HepG2	AKAP8L
SEC63	ENSG00000025796.9	3327.88900	4111.17390	-0.30490	5.46250	4.55420	HepG2	AUH
SEC63	ENSG00000025796.9	3509.28330	4382.31110	-0.32050	3.07610	2.44880	HepG2	BOP1
SEC63	ENSG00000025796.9	2956.18910	5162.98630	-0.80450	4.00540	2.81990	HepG2	CCAR1
SEC63	ENSG00000025796.9	2345.27220	2686.93410	-0.19620	2.74100	2.07790	HepG2	CKAP4
SEC63	ENSG00000025796.9	1460.15380	2384.23240	-0.70740	5.11450	4.07030	HepG2	CNOT7
SEC63	ENSG00000025796.9	3081.73740	3527.41370	-0.19490	2.86460	2.11150	HepG2	DAZAP1
SEC63	ENSG00000025796.9	2793.18280	2485.49370	0.16830	2.04170	1.31590	HepG2	DDX19B
SEC63	ENSG00000025796.9	2974.58480	2150.57970	0.46790	3.71200	2.25110	HepG2	DDX27
SEC63	ENSG00000025796.9	3225.24570	4473.44880	-0.47200	4.61800	3.82520	HepG2	DDX3X
SEC63	ENSG00000025796.9	1760.26580	2282.27520	-0.37470	3.58150	2.04600	HepG2	DDX52
SEC63	ENSG00000025796.9	1338.07000	2298.32560	-0.78040	8.66340	7.37760	HepG2	DDX55
SEC63	ENSG00000025796.9	4443.87990	3631.00350	0.29140	2.33230	1.40410	HepG2	DDX5
SEC63	ENSG00000025796.9	2595.33470	3842.46270	-0.56610	5.55200	4.70340	HepG2	DDX6
SEC63	ENSG00000025796.9	1569.92730	2302.82780	-0.55270	15.82470	14.39040	HepG2	DNAJC2
SEC63	ENSG00000025796.9	1643.78080	3694.17260	-1.16820	23.68780	22.06870	HepG2	EIF2S1
SEC63	ENSG00000025796.9	1557.58340	2210.81810	-0.50530	3.46940	2.46430	HepG2	EIF3D
SEC63	ENSG00000025796.9	2972.86080	4082.64970	-0.45770	3.73570	2.99710	HepG2	EIF4A3
SEC63	ENSG00000025796.9	4484.77920	3479.55340	0.36600	6.82260	5.61340	HepG2	EIF4G1
SEC63	ENSG00000025796.9	2154.95320	2626.17080	-0.28530	2.57890	1.77370	HepG2	EWSR1
SEC63	ENSG00000025796.9	1560.22200	1975.65990	-0.34060	3.00510	1.78040	HepG2	FAM120A
SEC63	ENSG00000025796.9	1859.44440	2322.36880	-0.32070	2.55640	1.45240	HepG2	FASTKD2
SEC63	ENSG00000025796.9	2837.60950	4311.98790	-0.60370	4.04770	3.13080	HepG2	FIP1L1
SEC63	ENSG00000025796.9	2975.58470	2456.40990	0.27650	2.55940	1.80210	HepG2	FUBP3
SEC63	ENSG00000025796.9	2353.81200	3202.40890	-0.44420	2.43880	1.38680	HepG2	FUS
SEC63	ENSG00000025796.9	2864.15180	4118.75420	-0.52410	5.72440	4.75230	HepG2	FXR1
SEC63	ENSG00000025796.9	2478.14860	3820.99480	-0.62470	6.95890	5.92350	HepG2	G3BP1
SEC63	ENSG00000025796.9	1876.23350	2394.15990	-0.35170	2.29520	1.37110	HepG2	GNB2L1
SEC63	ENSG00000025796.9	1377.33650	2345.63070	-0.76810	13.58510	12.32480	HepG2	HNRNPA1
SEC63	ENSG00000025796.9	2096.87420	3241.53850	-0.62840	15.12290	13.29480	HepG2	HNRNPA2B1
SEC63	ENSG00000025796.9	1899.87550	2609.07110	-0.45760	5.32200	4.38370	HepG2	HNRNPC
SEC63	ENSG00000025796.9	2937.06170	3868.52830	-0.39740	4.04340	3.21260	HepG2	HNRNPK
SEC63	ENSG00000025796.9	2783.42760	3213.36480	-0.20720	2.45510	1.81610	HepG2	HNRNPL
SEC63	ENSG00000025796.9	5228.08960	4352.14010	0.26450	2.00540	1.46070	HepG2	HNRNPLL
SEC63	ENSG00000025796.9	1736.77230	2591.82210	-0.57760	14.95750	13.64040	HepG2	HNRNPU
SEC63	ENSG00000025796.9	2899.30610	3884.04530	-0.42190	3.90320	3.11500	HepG2	IGF2BP2
SEC63	ENSG00000025796.9	1793.96800	2647.46210	-0.56150	18.83160	17.11280	HepG2	ILF2
SEC63	ENSG00000025796.9	3066.87130	4240.98690	-0.46760	4.32410	3.53890	HepG2	NCBP2
SEC63	ENSG00000025796.9	1677.70950	3497.74780	-1.05990	26.87880	24.69940	HepG2	NOL12
SEC63	ENSG00000025796.9	1199.76630	2110.24320	-0.81470	5.26610	3.73200	HepG2	NONO
SEC63	ENSG00000025796.9	6311.31060	3859.08240	0.70960	12.31590	10.84590	HepG2	NSUN2
SEC63	ENSG00000025796.9	3049.43810	3871.98770	-0.34450	6.63550	5.75720	HepG2	PCBP1
SEC63	ENSG00000025796.9	2633.92180	3939.87540	-0.58090	16.39450	15.27710	HepG2	PTBP1
SEC63	ENSG00000025796.9	2668.42150	3338.75920	-0.32330	3.52090	2.85930	HepG2	PUF60
SEC63	ENSG00000025796.9	2196.79150	2737.27000	-0.31730	5.62040	4.79780	HepG2	PUS1
SEC63	ENSG00000025796.9	3091.92950	4267.01830	-0.46470	8.58660	7.57910	HepG2	QKI
SEC63	ENSG00000025796.9	2947.13780	4230.15010	-0.52140	7.75880	6.42550	HepG2	RBM15
SEC63	ENSG00000025796.9	2563.46140	3945.21260	-0.62200	16.14420	15.10330	HepG2	RBM22
SEC63	ENSG00000025796.9	1625.55240	2296.30700	-0.49840	4.31180	2.98610	HepG2	RCC2
SEC63	ENSG00000025796.9	2990.90010	4384.71700	-0.55190	15.59740	14.50950	HepG2	NELFE
SEC63	ENSG00000025796.9	1576.03150	2151.10240	-0.44880	4.72680	3.94680	HepG2	RPS19
SEC63	ENSG00000025796.9	2074.45220	2608.12240	-0.33030	2.37700	1.63050	HepG2	RPS2
SEC63	ENSG00000025796.9	4169.10120	2308.13780	0.85290	42.00230	39.94930	HepG2	SAFB2
SEC63	ENSG00000025796.9	3798.85860	4743.01460	-0.32020	1.87360	1.31610	HepG2	SF3A3
SEC63	ENSG00000025796.9	5148.68950	4307.69710	0.25720	2.02190	1.41360	HepG2	SF3B1
SEC63	ENSG00000025796.9	3163.53310	4101.94900	-0.37480	7.81870	6.90520	HepG2	SF3B4
SEC63	ENSG00000025796.9	2276.69230	2691.68810	-0.24160	4.21490	3.45070	HepG2	SMN1
SEC63	ENSG00000025796.9	3052.40540	4455.96220	-0.54580	17.48220	16.50810	HepG2	SRFBP1
SEC63	ENSG00000025796.9	3687.07500	4281.53440	-0.21570	3.44220	2.92970	HepG2	SRSF1
SEC63	ENSG00000025796.9	2813.27950	3296.33180	-0.22860	3.37860	2.69910	HepG2	SRSF5
SEC63	ENSG00000025796.9	3099.80490	3483.24560	-0.16830	2.05780	1.56710	HepG2	SRSF9
SEC63	ENSG00000025796.9	2992.94120	3749.01430	-0.32490	4.67500	3.90390	HepG2	SUCLG1
SEC63	ENSG00000025796.9	1877.81570	2518.47500	-0.42350	5.81250	5.13840	HepG2	TIAL1
SEC63	ENSG00000025796.9	2226.81650	2540.95020	-0.19040	2.17850	1.66620	HepG2	TRIM56
SEC63	ENSG00000025796.9	3421.63490	4206.33640	-0.29790	5.71360	4.76740	HepG2	UPF1
SEC63	ENSG00000025796.9	3695.92780	4323.46870	-0.22630	2.91970	1.84670	HepG2	UTP18
SEC63	ENSG00000025796.9	1595.88220	4061.04090	-1.34750	76.41310	73.97660	HepG2	UTP3
SEC63	ENSG00000025796.9	3293.17240	2919.99210	0.17340	2.34670	1.72130	HepG2	ZC3H8
SEC63	ENSG00000025796.9	2549.95940	4626.15410	-0.85930	50.05610	48.47720	HepG2	ZNF622
SEC63	ENSG00000025796.9	3836.80440	6059.20460	-0.65920	23.67050	22.12380	K562	AGGF1
SEC63	ENSG00000025796.9	5355.59780	6304.91770	-0.23540	1.83930	1.30230	K562	AKAP8L
SEC63	ENSG00000025796.9	2523.50170	4043.07080	-0.68000	10.49240	9.45930	K562	AQR
SEC63	ENSG00000025796.9	1559.35670	2022.15000	-0.37490	3.81910	2.68000	K562	BCLAF1
SEC63	ENSG00000025796.9	3664.63320	6090.20170	-0.73280	5.48810	3.93060	K562	CNOT7
SEC63	ENSG00000025796.9	3703.90160	4972.93460	-0.42510	8.78650	6.80510	K562	CPEB4
SEC63	ENSG00000025796.9	2945.46460	4065.54250	-0.46500	6.08200	4.92220	K562	CPSF6
SEC63	ENSG00000025796.9	1997.63410	2464.35710	-0.30290	2.88250	1.81970	K562	DDX3X
SEC63	ENSG00000025796.9	8147.39400	6784.28800	0.26400	4.13310	3.03240	K562	DKC1
SEC63	ENSG00000025796.9	1412.55570	1766.40240	-0.32250	2.22830	1.40930	K562	EFTUD2
SEC63	ENSG00000025796.9	2059.26300	2706.94010	-0.39450	6.89690	4.94740	K562	EIF2S1
SEC63	ENSG00000025796.9	3374.99980	2799.98770	0.26940	3.58810	2.78610	K562	EIF2S2
SEC63	ENSG00000025796.9	1784.20820	1258.15390	0.50390	2.78510	1.77740	K562	EIF3A
SEC63	ENSG00000025796.9	1445.00190	1891.46440	-0.38840	2.51080	1.53150	K562	EIF3D
SEC63	ENSG00000025796.9	4056.10040	5250.61420	-0.37240	6.61910	5.18880	K562	EIF4G2
SEC63	ENSG00000025796.9	2602.65980	3789.17630	-0.54190	2.59630	1.77560	K562	FIP1L1
SEC63	ENSG00000025796.9	3128.02610	4136.37240	-0.40310	4.23410	3.17610	K562	FMR1
SEC63	ENSG00000025796.9	2795.18390	3505.85290	-0.32680	2.57530	1.69640	K562	FTO
SEC63	ENSG00000025796.9	2273.72350	2677.54790	-0.23590	2.61430	2.02270	K562	FXR1
SEC63	ENSG00000025796.9	4414.36050	2984.86640	0.56440	4.73880	3.75670	K562	G3BP2
SEC63	ENSG00000025796.9	3111.67140	3881.68370	-0.31900	2.50410	1.74570	K562	GPKOW
SEC63	ENSG00000025796.9	2389.79220	3731.34870	-0.64280	11.61580	10.04140	K562	GRSF1
SEC63	ENSG00000025796.9	1476.05370	2496.78600	-0.75830	9.47770	8.42570	K562	HNRNPC
SEC63	ENSG00000025796.9	3830.43570	4649.97280	-0.27970	2.73710	1.69010	K562	HNRNPL
SEC63	ENSG00000025796.9	3020.34870	3673.62690	-0.28250	2.72220	1.89020	K562	MAGOH
SEC63	ENSG00000025796.9	2469.03870	3788.91800	-0.61780	9.41300	7.73040	K562	METAP2
SEC63	ENSG00000025796.9	4597.78780	5596.65190	-0.28360	2.34730	1.31140	K562	MSI2
SEC63	ENSG00000025796.9	2518.10220	3420.87250	-0.44200	10.67860	9.19950	K562	MTPAP
SEC63	ENSG00000025796.9	4257.28520	5743.24240	-0.43190	5.23860	3.14000	K562	NOL12
SEC63	ENSG00000025796.9	1072.91830	1740.03490	-0.69760	7.97650	5.57880	K562	NONO
SEC63	ENSG00000025796.9	3004.51430	3800.99190	-0.33920	9.84560	8.55420	K562	NSUN2
SEC63	ENSG00000025796.9	3403.87880	5850.89770	-0.78150	6.13840	4.28830	K562	PABPC1
SEC63	ENSG00000025796.9	2472.84840	3268.66260	-0.40250	4.52720	3.26960	K562	PCBP2
SEC63	ENSG00000025796.9	2816.36850	4300.98650	-0.61080	3.29000	2.38170	K562	PPIG
SEC63	ENSG00000025796.9	2084.58770	3569.14040	-0.77580	17.20400	15.61520	K562	PTBP1
SEC63	ENSG00000025796.9	4436.04090	5970.43970	-0.42860	8.79020	7.05350	K562	PUM2
SEC63	ENSG00000025796.9	4819.87180	6252.45800	-0.37540	3.75620	3.13730	K562	PUS1
SEC63	ENSG00000025796.9	2441.50600	3422.51230	-0.48730	5.96320	4.67040	K562	RBM22
SEC63	ENSG00000025796.9	1472.54690	2041.95690	-0.47160	5.30970	3.92850	K562	RCC2
SEC63	ENSG00000025796.9	2799.83060	3601.61560	-0.36330	3.24390	2.05070	K562	NELFE
SEC63	ENSG00000025796.9	2287.83250	1751.03400	0.38570	2.94320	2.10000	K562	RPS19
SEC63	ENSG00000025796.9	2669.88530	3750.46720	-0.49030	10.33590	8.83580	K562	SF3A3
SEC63	ENSG00000025796.9	4014.08210	6537.27870	-0.70360	3.25610	1.80020	K562	SFPQ
SEC63	ENSG00000025796.9	1554.98500	1935.76430	-0.31600	2.56480	1.58840	K562	SRFBP1
SEC63	ENSG00000025796.9	3085.38850	3842.42180	-0.31660	6.95290	5.54430	K562	SRPK2
SEC63	ENSG00000025796.9	2580.57490	3498.92030	-0.43920	6.08070	5.04010	K562	SRSF1
SEC63	ENSG00000025796.9	2681.70190	2178.13090	0.30000	3.27790	2.38470	K562	SYNCRIP
SEC63	ENSG00000025796.9	1464.71100	3541.19440	-1.27360	31.18150	28.24720	K562	TARDBP
SEC63	ENSG00000025796.9	1466.44840	2153.15470	-0.55410	5.55700	4.18730	K562	TIAL1
SEC63	ENSG00000025796.9	1824.97730	2286.97630	-0.32560	2.75420	1.81210	K562	TRIM56
SEC63	ENSG00000025796.9	2726.72630	3448.58260	-0.33880	3.82960	2.79480	K562	WDR3
SEC63	ENSG00000025796.9	3801.09960	4554.25630	-0.26080	2.18710	1.43060	K562	ZC3H8
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for SEC63 is not available on ENCORE database.

5 RBPs can affect the splicing of SEC63 :

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	SEC63	ENSG00000025796.9	chr6	-	108197767	108197866			108194011	108194116	108202352	108202454	-0.05400	0.00263	0.04545	excluded	HepG2	U2AF1
SE	SEC63	ENSG00000025796.9	chr6	-	108250618	108250718			108246021	108246136	108279089	108279135	-0.07000	0.00002	0.00074	excluded	HepG2	U2AF1
SE	SEC63	ENSG00000025796.9	chr6	-	108197767	108197866			108194011	108194116	108202352	108202454	-0.12000	0.00000	0.00000	excluded	HepG2	U2AF2
SE	SEC63	ENSG00000025796.9	chr6	-	108197794	108197866			108194011	108194116	108202352	108202454	-0.07400	0.00014	0.00227	excluded	K562	AQR
A3SS	SEC63	ENSG00000025796.9	chr6	-	108224047	108224238			108224047	108224202	108225832	108225925	0.07300	0.00000	0.00006	longer	HepG2	RBM22
A3SS	SEC63	ENSG00000025796.9	chr6	-	108222573	108222768			108222573	108222721	108224047	108224202	0.07100	0.00000	0.00002	longer	K562	AQR
A3SS	SEC63	ENSG00000025796.9	chr6	-	108225832	108225988			108225832	108225925	108227651	108227784	0.16600	0.00000	0.00000	longer	K562	AQR
A3SS	SEC63	ENSG00000025796.9	chr6	-	108246021	108246187			108246021	108246136	108250618	108250718	0.06600	0.00000	0.00000	longer	K562	AQR
A3SS	SEC63	ENSG00000025796.9	chr6	-	108204191	108204414			108204191	108204350	108214685	108214859	0.09800	0.00000	0.00000	longer	K562	AQR
A3SS	SEC63	ENSG00000025796.9	chr6	-	108232549	108232692			108232549	108232600	108233919	108234013	0.05700	0.01452	0.07275	longer	K562	AQR
A3SS	SEC63	ENSG00000025796.9	chr6	-	108194011	108194249			108194011	108194116	108197767	108197866	0.08300	0.00000	0.00000	longer	K562	AQR
A3SS	SEC63	ENSG00000025796.9	chr6	-	108215041	108215140			108215041	108215101	108218852	108218935	0.06200	0.00002	0.00019	longer	K562	AQR
A3SS	SEC63	ENSG00000025796.9	chr6	-	108224047	108224238			108224047	108224202	108225832	108225944	0.11200	0.00000	0.00000	longer	K562	AQR
A3SS	SEC63	ENSG00000025796.9	chr6	-	108233919	108234013			108233919	108233978	108234569	108234631	0.07400	0.00278	0.01723	longer	K562	AQR
MXE	SEC63	ENSG00000025796.9	chr6	-	108194011	108194116	108197767	108197866	108188959	108193051	108202352	108202454	-0.06900	0.00070	0.01731	2included	HepG2	FTO

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

SEC63

General Information

Functions

Localization

Domains (AlphaFold: SEC63)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for SEC63 is not avaliable on ENCORE database.

34 proteins are bound to SEC63 RNA:

eCLIP assay for SEC63 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for SEC63 is not available on ENCORE database.

100 RBPs can affect the gene expression of SEC63 :

The Knockdown/knockout RNA-Seq assay for SEC63 is not available on ENCORE database.

5 RBPs can affect the splicing of SEC63 :

The Knockdown/knockout RNA-Seq assay for SEC63 is not avaliable on ENCORE database.