PITX1

General Information

Gene Name       : PITX1
Gene ID             : ENSG00000069011.15
Essential Gene : No

Functions

Localization

Domains (AlphaFold: PITX1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PITX1ENSG00000069011.150.000.000.00ENCSR000AEF
HepG2PITX1ENSG00000069011.1526.791.9614.38ENCSR985KAT
K562PITX1ENSG00000069011.1525.714.9615.34ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PITX1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • PITX1 RNA is bound by 12 proteins.  







eCLIP assay for PITX1 is not avaliable on ENCORE database.





12 proteins are bound to PITX1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr5134363665134363710-3'-UTR,intron-Distal4.182154.32914K562YBX3
chr5134363798134363904-3'-UTR,intron-Distal5.4857210.54419K562UPF1
chr5134364091134364181-3'-UTR,intron-Distal,intron-Proximal4.198603.90326K562DDX6
chr5134364189134364239-3'-UTR,intron-Distal,intron-Proximal5.181008.74631K562PABPC4
chr5134364460134364528-3'-UTR,CDS,intron-Distal3.558764.14411K562METAP2
chr5134363636134363690-3'-UTR,intron-Distal4.489213.67707K562METAP2
chr5134364117134364182-3'-UTR,intron-Distal,intron-Proximal3.085026.32251K562UPF1
chr5134364880134364928-3'-UTR,CDS,intron-Distal,intron-Proximal3.050096.43544K562YBX3
chr5134364130134364189-3'-UTR,intron-Distal,intron-Proximal4.5824013.16793K562PABPC4
chr5134363748134363882-3'-UTR,intron-Distal3.529363.39697K562DGCR8
chr5134364102134364173-3'-UTR,intron-Distal,intron-Proximal3.619906.27327K562RBM15
chr5134364057134364169-3'-UTR,intron-Distal,intron-Proximal4.124835.11568K562PUM1
chr5134363987134364059-3'-UTR,intron-Distal4.680704.90799K562UPF1
chr5134369743134369882-5'-UTR,intron-Distal4.3404311.21395HepG2DDX3X
chr5134369609134369674-5'-UTR,intron-Distal,intron-Proximal4.690235.35746HepG2DDX3X
chr5134369783134369907-5'-UTR,intron-Distal5.2769010.52122K562DDX3X
chr5134364755134364818-CDS,intron-Distal,intron-Proximal3.0962314.28165K562YBX3
chr5134364590134364631-CDS,intron-Distal3.747315.71420K562RBM15
chr5134364952134364970-CDS,intron-Distal,intron-Proximal3.673629.47757K562YBX3
chr5134364492134364531-CDS,intron-Distal3.922565.71420K562RBM15
chr5134364928134364952-CDS,intron-Distal,intron-Proximal3.9646411.45100K562YBX3
chr5134366962134367028-CDS,intron-Distal,intron-Proximal4.016444.73981K562METAP2
chr5134367116134367186-CDS,intron-Distal4.373084.22893K562RBM15
chr5134368839134368932-intron-Distal,intron-Proximal4.085033.95960K562SAFB2
chr5134367259134367303-intron-Distal,intron-Proximal4.023583.73926K562RBM15
chr5134368840134368931-intron-Distal,intron-Proximal3.668233.30889K562GTF2F1
chr5134369358134369403-intron-Distal,intron-Proximal4.2845913.60040K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PITX1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PITX1 is not available on ENCORE database.

  • 127 RBPs can affect the levels of PITX1.  








The Knockdown/knockout RNA-Seq assay for PITX1 is not available on ENCORE database.





127 RBPs can affect the gene expression of PITX1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PITX1ENSG00000069011.11469.08660256.285500.872006.474505.10230HepG2ABCF1
PITX1ENSG00000069011.11334.76040185.647400.850507.927907.00660HepG2ACO1
PITX1ENSG00000069011.11263.30040186.500000.497402.691601.93420HepG2AKAP8L
PITX1ENSG00000069011.11338.01910231.372100.546803.014001.54760HepG2ATP5C1
PITX1ENSG00000069011.11348.80060258.036900.434702.046001.52570HepG2BOP1
PITX1ENSG00000069011.1154.35050117.30110-1.109904.000103.09640HepG2CALR
PITX1ENSG00000069011.1188.4463042.695401.050602.845701.75580HepG2CSTF2
PITX1ENSG00000069011.11123.6468049.441301.322306.020605.14130HepG2CELF1
PITX1ENSG00000069011.11233.85890171.686400.445802.342401.57060HepG2DDX19B
PITX1ENSG00000069011.11261.35130124.004501.075503.861903.13390HepG2DDX3X
PITX1ENSG00000069011.11146.2912068.004401.105003.421102.57190HepG2DDX55
PITX1ENSG00000069011.11355.61250106.602901.738002.753602.13710HepG2DDX6
PITX1ENSG00000069011.1162.6128029.972301.062702.627101.93810HepG2DNAJC21
PITX1ENSG00000069011.11112.9091029.708801.926107.408706.41250HepG2DNAJC2
PITX1ENSG00000069011.11226.6072080.892701.486006.834105.45230HepG2EEF2
PITX1ENSG00000069011.11286.95440194.466200.561203.080501.84290HepG2EIF2S2
PITX1ENSG00000069011.11136.4382050.249101.441005.576204.44230HepG2EIF4G2
PITX1ENSG00000069011.11255.92460181.389700.496502.294101.53440HepG2EWSR1
PITX1ENSG00000069011.11390.23380258.801100.592403.167002.34960HepG2FIP1L1
PITX1ENSG00000069011.1176.53530127.45880-0.735802.122901.42670HepG2FUBP3
PITX1ENSG00000069011.11234.36970114.255801.036405.140904.21890HepG2FXR1
PITX1ENSG00000069011.11107.2642042.517801.334903.070001.62850HepG2HNRNPA0
PITX1ENSG00000069011.11103.2308030.259401.770303.072202.39510HepG2HNRNPA1
PITX1ENSG00000069011.11110.3710041.502301.411003.382501.83000HepG2HNRNPAB
PITX1ENSG00000069011.11238.24460175.270900.442802.208901.56250HepG2HNRNPF
PITX1ENSG00000069011.11164.53570107.404800.615201.994701.39480HepG2HNRNPK
PITX1ENSG00000069011.11125.7828048.461901.375906.659005.65770HepG2HNRNPL
PITX1ENSG00000069011.11127.17840256.23660-1.010606.015805.12470HepG2HNRNPLL
PITX1ENSG00000069011.11255.24830178.601100.515102.515601.60610HepG2HNRNPM
PITX1ENSG00000069011.11123.5484033.435901.8855010.990909.84920HepG2HNRNPU
PITX1ENSG00000069011.11170.23250107.651100.661002.281801.66220HepG2IGF2BP2
PITX1ENSG00000069011.11144.2648047.891201.590805.053303.37780HepG2KHDRBS1
PITX1ENSG00000069011.11113.38570169.69030-0.581702.265501.34120HepG2KIF1C
PITX1ENSG00000069011.11683.37320258.614101.401809.628708.08130HepG2LARP4
PITX1ENSG00000069011.11123.0997040.355601.608905.660104.05310HepG2LARP7
PITX1ENSG00000069011.11234.92520114.296201.039305.801404.86290HepG2MAGOH
PITX1ENSG00000069011.11374.50480114.916901.7043015.7950014.38130HepG2MATR3
PITX1ENSG00000069011.11334.26860117.608401.5069012.8787011.56950HepG2NCBP2
PITX1ENSG00000069011.11159.5830052.742501.597204.553703.57560HepG2NOL12
PITX1ENSG00000069011.11138.2080066.581501.053503.827502.14520HepG2NOLC1
PITX1ENSG00000069011.11382.6899062.487402.6144020.8621017.81400HepG2NONO
PITX1ENSG00000069011.11127.43830227.22100-0.834304.021103.12370HepG2NSUN2
PITX1ENSG00000069011.11103.6768041.012701.337803.926801.55230HepG2NUSAP1
PITX1ENSG00000069011.11102.3697049.032101.061903.058901.38230HepG2PA2G4
PITX1ENSG00000069011.11124.6463045.833201.443302.353501.54700HepG2PABPC1
PITX1ENSG00000069011.11182.40360100.261600.863304.505903.76310HepG2PCBP1
PITX1ENSG00000069011.11124.7650029.822002.0647012.6998011.18490HepG2PPIL4
PITX1ENSG00000069011.1186.44720165.71330-0.938805.023404.01320HepG2PRPF4
PITX1ENSG00000069011.11220.88970102.010201.114507.296706.49150HepG2PTBP1
PITX1ENSG00000069011.11138.2605050.339201.457506.908506.02210HepG2PUF60
PITX1ENSG00000069011.11243.9600053.427702.1909024.9972023.58250HepG2PUM1
PITX1ENSG00000069011.11156.7736053.394601.553802.223601.61960HepG2PUM2
PITX1ENSG00000069011.11272.26170189.090500.525803.065202.42470HepG2PUS1
PITX1ENSG00000069011.11182.6613069.470801.394603.473601.42050HepG2RBM17
PITX1ENSG00000069011.11189.9727048.669601.964607.566005.91340HepG2RBM27
PITX1ENSG00000069011.11129.1863039.522601.708606.173304.58920HepG2RCC2
PITX1ENSG00000069011.11247.73000113.535601.125507.829407.00130HepG2NELFE
PITX1ENSG00000069011.11243.4200063.897101.929508.403307.40080HepG2RPS19
PITX1ENSG00000069011.11185.8501044.873402.0501012.1744010.59080HepG2RPS2
PITX1ENSG00000069011.11119.9299050.454001.249102.075501.38240HepG2RPS3A
PITX1ENSG00000069011.11127.7755045.819801.479504.951503.49810HepG2RPS5
PITX1ENSG00000069011.1197.2415029.775901.707307.679606.68620HepG2SAFB2
PITX1ENSG00000069011.11599.79720231.261101.3749014.6578013.03570HepG2SF3A3
PITX1ENSG00000069011.11134.13330253.60900-0.918905.293004.33930HepG2SF3B1
PITX1ENSG00000069011.11175.9608065.164901.433003.475701.80310HepG2SFPQ
PITX1ENSG00000069011.11135.0122048.247701.484507.201906.15380HepG2SLBP
PITX1ENSG00000069011.11126.4459034.723301.8644010.848609.70800HepG2SMN1
PITX1ENSG00000069011.11147.9625053.787101.459802.518301.60730HepG2SMNDC1
PITX1ENSG00000069011.11114.99270282.18980-1.295107.359406.07970HepG2SNRNP70
PITX1ENSG00000069011.11180.3389049.691101.859608.408607.39300HepG2SRSF5
PITX1ENSG00000069011.11139.4466043.942801.665907.007005.19810HepG2STIP1
PITX1ENSG00000069011.11285.1170056.522302.3346023.1649021.64880HepG2SUCLG1
PITX1ENSG00000069011.1120.9921099.63180-2.2468010.610009.62550HepG2TAF15
PITX1ENSG00000069011.11114.4052045.358701.334604.705403.45360HepG2TFIP11
PITX1ENSG00000069011.11158.0785032.487802.282605.988605.30600HepG2TIAL1
PITX1ENSG00000069011.11124.4113032.779701.9241011.6727010.63060HepG2TRIM56
PITX1ENSG00000069011.11193.8725049.163601.979304.313103.19320HepG2TUFM
PITX1ENSG00000069011.11447.22340221.423201.014108.927907.79200HepG2U2AF1
PITX1ENSG00000069011.11239.1119069.702601.778303.025201.99080HepG2U2AF2
PITX1ENSG00000069011.11238.1750052.028602.194503.057102.17930HepG2UBE2L3
PITX1ENSG00000069011.11138.9531039.974501.797303.241502.42080HepG2UCHL5
PITX1ENSG00000069011.11381.99830198.009900.947905.836605.02040HepG2UTP3
PITX1ENSG00000069011.11125.7328045.200401.475904.708103.26310HepG2XPO5
PITX1ENSG00000069011.11186.9255066.628301.488206.881905.75330HepG2XRN2
PITX1ENSG00000069011.11467.91180225.563601.0526011.1622010.24510HepG2ZNF622
PITX1ENSG00000069011.111211.34280700.217700.7906016.6508015.38280K562AGGF1
PITX1ENSG00000069011.111053.60760769.459900.453304.256302.98270K562AKAP8
PITX1ENSG00000069011.111227.17450728.614800.752004.217303.40840K562AKAP8L
PITX1ENSG00000069011.111344.36970848.869300.663203.123502.50730K562AQR
PITX1ENSG00000069011.111044.41240764.504600.450005.350504.03150K562ATP5C1
PITX1ENSG00000069011.11526.02170200.986001.3879022.3858019.78650K562BCLAF1
PITX1ENSG00000069011.11609.14840370.050300.719003.326402.14840K562CCAR1
PITX1ENSG00000069011.111064.71080723.086500.558104.050102.25390K562CKAP4
PITX1ENSG00000069011.11498.54610152.477901.709003.911002.62470K562CSTF2
PITX1ENSG00000069011.111099.81410821.547500.420703.562001.89010K562DDX19B
PITX1ENSG00000069011.111171.22170721.549700.6987010.389408.04880K562DDX21
PITX1ENSG00000069011.11319.85480176.193800.860207.624705.43290K562DDX27
PITX1ENSG00000069011.111515.27240984.931000.6214012.3193011.05050K562DDX47
PITX1ENSG00000069011.11384.46470175.548501.130904.051002.00990K562DDX51
PITX1ENSG00000069011.11637.87250168.076201.924102.689501.43090K562EEF2
PITX1ENSG00000069011.11433.79830162.300901.418308.614906.92190K562EFTUD2
PITX1ENSG00000069011.11562.53380376.379400.579702.528001.57070K562EIF3A
PITX1ENSG00000069011.11434.74750173.617101.324206.903105.17030K562EIF3D
PITX1ENSG00000069011.11177.9339096.724600.879303.891602.95710K562EIF3G
PITX1ENSG00000069011.11367.06760164.110701.161303.597001.39480K562EIF3H
PITX1ENSG00000069011.11625.92670393.075400.671107.895005.80660K562EIF4B
PITX1ENSG00000069011.111758.99370916.487200.940508.586106.95950K562EIF4G2
PITX1ENSG00000069011.11865.20820671.415900.365702.198701.44200K562FIP1L1
PITX1ENSG00000069011.11825.62710453.898100.8630014.3077013.03880K562FXR1
PITX1ENSG00000069011.119.9806043.59130-2.126804.501903.55440K562G3BP2
PITX1ENSG00000069011.11593.76820426.307400.477903.348302.47640K562GPKOW
PITX1ENSG00000069011.111420.56710800.590700.827202.871902.10380K562GRSF1
PITX1ENSG00000069011.11739.67220449.241300.719303.199601.85830K562HNRNPA2B1
PITX1ENSG00000069011.11778.81440552.201600.496002.628701.72380K562HNRNPM
PITX1ENSG00000069011.11641.21620910.36410-0.505602.269701.54480K562HSPD1
PITX1ENSG00000069011.11435.83860124.265401.810303.748002.48500K562IGF2BP2
PITX1ENSG00000069011.11369.32760130.530401.5004018.4914016.15760K562MAGOH
PITX1ENSG00000069011.11984.57190740.179900.411503.461602.21470K562MAK16
PITX1ENSG00000069011.11333.53930130.255301.356402.291001.45820K562MATR3
PITX1ENSG00000069011.111211.92150866.204300.484405.608604.22340K562MBNL1
PITX1ENSG00000069011.11518.39410160.305801.693104.439202.68470K562NONO
PITX1ENSG00000069011.111276.769101035.225900.302503.922303.05220K562NSUN2
PITX1ENSG00000069011.11700.70790393.044800.834003.917202.68410K562PABPN1
PITX1ENSG00000069011.11184.48590116.127300.667702.291501.40630K562PCBP2
PITX1ENSG00000069011.11461.53180157.941501.546908.838007.49380K562PRPF8
PITX1ENSG00000069011.11439.24720126.823501.7921024.6838022.78390K562PTBP1
PITX1ENSG00000069011.11688.36960394.878700.801704.950302.31190K562RBFOX2
PITX1ENSG00000069011.111132.46450704.044300.685603.784603.10710K562RBM15
PITX1ENSG00000069011.11338.11420121.571601.4756016.1144013.89500K562RBM22
PITX1ENSG00000069011.111030.03990505.591001.026609.548907.60640K562SAFB
PITX1ENSG00000069011.11951.61880485.392600.971103.186401.53420K562SBDS
PITX1ENSG00000069011.11269.18150405.54660-0.591302.241801.37640K562SF3B1
PITX1ENSG00000069011.11106.8110045.285301.237805.275804.07250K562SF3B4
PITX1ENSG00000069011.11690.02440438.341500.654502.528201.30260K562SFPQ
PITX1ENSG00000069011.11405.57200157.866701.361206.505903.87470K562SRP68
PITX1ENSG00000069011.11383.33930124.336901.6243018.5685016.75590K562SRSF1
PITX1ENSG00000069011.11487.00590202.339101.2671012.7548010.35310K562SRSF4
PITX1ENSG00000069011.11264.61950117.445601.171809.253907.22470K562SRSF5
PITX1ENSG00000069011.11478.27240881.01030-0.881305.495103.53900K562SSRP1
PITX1ENSG00000069011.11583.62670805.84280-0.465502.797901.53960K562STAU1
PITX1ENSG00000069011.11371.89640152.716601.283904.717203.36040K562SUPV3L1
PITX1ENSG00000069011.11457.90960125.820701.8636010.559409.02850K562TARDBP
PITX1ENSG00000069011.11411.37940121.372501.7609013.6864011.74350K562TIA1
PITX1ENSG00000069011.11303.61230119.141301.349504.463603.01570K562TRA2A
PITX1ENSG00000069011.11406.97230161.734201.331205.002503.58740K562UCHL5
PITX1ENSG00000069011.11768.45740976.67230-0.345903.817302.83380K562WDR43
PITX1ENSG00000069011.11491.37220164.852401.5755011.409008.61760K562XRN2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PITX1 is not available on ENCORE database.





1 RBPs can affect the splicing of PITX1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
A3SSPITX1ENSG00000069011.11chr5-1343649111343651031343649111343650111343669651343671980.071000.000000.00000longerK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PITX1 is not avaliable on ENCORE database.