KLHDC3

General Information

Gene Name       : KLHDC3
Gene ID             : ENSG00000124702.17
Essential Gene : No

Functions

Localization

Domains (AlphaFold: KLHDC3)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878KLHDC3ENSG00000124702.1730.9838.6234.80ENCSR000AEF
HepG2KLHDC3ENSG00000124702.1776.4559.2367.84ENCSR985KAT
K562KLHDC3ENSG00000124702.17115.06112.71113.88ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for KLHDC3 is not avaliable on ENCORE database.



Proteins bound to RNA
  • KLHDC3 RNA is bound by 25 proteins.  







eCLIP assay for KLHDC3 is not avaliable on ENCORE database.





25 proteins are bound to KLHDC3 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr64298894042988995+3'-UTR5.3231224.04927K562PABPC4
chr64298881442988920+3'-UTR4.010246.47490HepG2UPF1
chr64298874442988776+3'-UTR4.119998.50867K562PABPC4
chr64298848742988541+3'-UTR4.329537.73571HepG2LARP4
chr64298881042988855+3'-UTR3.771965.76765HepG2LARP4
chr64298880142988909+3'-UTR4.1465821.56615K562UPF1
chr64298854442988561+3'-UTR3.6054611.95636K562YBX3
chr64298866242988754+3'-UTR3.3513210.53529K562PCBP1
chr64298867842988778+3'-UTR3.2678513.19517K562UPF1
chr64298857742988687+3'-UTR3.1584213.50285HepG2SUB1
chr64298872542988766+3'-UTR3.814347.16338HepG2LARP4
chr64298894542988980+3'-UTR3.860614.63830HepG2LARP4
chr64298885542988915+3'-UTR3.629444.53936K562METAP2
chr64298884142988899+3'-UTR3.7597414.11909K562PABPC4
chr64298865742988751+3'-UTR4.853586.80118HepG2PCBP1
chr64298850842988544+3'-UTR3.5806312.87893K562YBX3
chr64298885542988916+3'-UTR3.383796.42991HepG2LARP4
chr64298888242988969+3'-UTR4.259037.11103K562PCBP1
chr64298864442988761+3'-UTR3.394695.63905HepG2AKAP1
chr64298859942988780+3'-UTR4.8417219.21704HepG2UPF1
chr64298199742982081+5'-UTR3.4266412.09617K562DDX3X
chr64298499342985048+5'-UTR,CDS4.040454.38588HepG2DDX3X
chr64298487142985044+5'-UTR,CDS,intron-Proximal3.035839.67215K562FTO
chr64298492142984983+5'-UTR,CDS3.9562323.07160HepG2DDX3X
chr64298201142982082+5'-UTR3.745216.89131K562DHX30
chr64298487342984921+5'-UTR4.384819.09300HepG2DDX3X
chr64298519042985265+5'-UTR,CDS,intron-Distal,intron-Proximal4.165928.86977HepG2EFTUD2
chr64298200342982085+5'-UTR4.1517427.29298HepG2DDX3X
chr64298199442982081+5'-UTR5.8746913.06351K562GEMIN5
chr64298491242984989+5'-UTR,CDS3.018403.46130HepG2PRPF4
chr64298487442984919+5'-UTR4.181093.66349K562LIN28B
chr64298487542984996+5'-UTR,CDS4.1865229.82431K562DDX3X
chr64298567342985699+CDS,intron-Distal5.9472757.90974K562PUM2
chr64298688242986903+CDS3.451984.19285K562IGF2BP1
chr64298563942985673+CDS,intron-Distal4.9275121.84350K562PUM2
chr64298709642987104+CDS3.269837.33020K562YBX3
chr64298585742985914+CDS,intron-Proximal3.655109.17929K562BUD13
chr64298709942987164+CDS,intron-Proximal5.417248.88638HepG2AQR
chr64298710042987149+CDS,intron-Proximal3.850155.90868HepG2PRPF8
chr64298669142986709+CDS3.281183.05460HepG2PPIG
chr64298707242987096+CDS4.0773012.08941K562YBX3
chr64298836042988435+CDS,intron-Proximal3.662635.75231K562AQR
chr64298603842986107+CDS,intron-Proximal4.0737111.42156HepG2EFTUD2
chr64298552842985606+CDS,intron-Distal,intron-Proximal3.739725.85504K562SF3B4
chr64298569942985706+CDS,intron-Distal5.7888942.59069K562PUM2
chr64298706942987072+CDS5.008128.97367K562YBX3
chr64298583942985896+CDS,intron-Proximal3.984245.93727K562SF3B4
chr64298585742985911+CDS,intron-Proximal3.114456.18258HepG2U2AF2
chr64298623442986281+CDS3.0854210.02415K562YBX3
chr64298710242987171+CDS,intron-Proximal4.0157610.38502K562AQR
chr64298583942985893+CDS,intron-Proximal3.284595.11990K562AQR
chr64298838142988429+CDS,intron-Proximal3.686183.39008HepG2AQR
chr64298592342985955+CDS,intron-Proximal4.2783718.97391K562PUM2
chr64298588142985904+CDS,intron-Proximal5.0042535.93126K562PUM2
chr64298702442987057+CDS,intron-Proximal3.319176.13150K562IGF2BP1
chr64298681642986864+CDS,intron-Proximal3.056884.81700HepG2U2AF2
chr64298608042986109+CDS,intron-Proximal4.5939214.14980K562PUM2
chr64298236742982413+intron-Distal3.768163.15816HepG2PRPF4
chr64298218842982303+intron-Distal3.068353.38609HepG2FAM120A
chr64298220342982250+intron-Distal3.656963.15816HepG2PRPF4
chr64298256742982722+intron-Distal4.967544.59504K562RBFOX2
chr64298235342982437+intron-Distal3.734736.39220HepG2RBFOX2
chr64298243742982542+intron-Distal4.0435611.19842HepG2RBFOX2
chr64298719542987269+intron-Distal,intron-Proximal3.715486.32052K562AQR
chr64298219742982297+intron-Distal4.161966.35159HepG2RBFOX2
chr64298246242982567+intron-Distal4.281515.41630K562RBFOX2
chr64298633542986371+intron-Proximal4.059346.95984K562EFTUD2
chr64298653342986595+intron-Proximal6.147139.06724K562EFTUD2
chr64298831942988381+intron-Proximal5.046526.03362HepG2AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for KLHDC3 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for KLHDC3 is not available on ENCORE database.

  • 104 RBPs can affect the levels of KLHDC3.  








The Knockdown/knockout RNA-Seq assay for KLHDC3 is not available on ENCORE database.





104 RBPs can affect the gene expression of KLHDC3 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
KLHDC3ENSG00000124702.131669.368002017.50700-0.273303.877703.18070HepG2ACO1
KLHDC3ENSG00000124702.13887.913901599.91140-0.8495012.2578010.37510HepG2ADAR
KLHDC3ENSG00000124702.131751.347703451.26660-0.9787014.2149013.10720HepG2AKAP1
KLHDC3ENSG00000124702.132323.077702026.880500.196702.060601.38540HepG2AKAP8L
KLHDC3ENSG00000124702.133685.925502712.729200.442205.868604.93130HepG2AUH
KLHDC3ENSG00000124702.131800.00220954.019700.9158015.7874014.52540HepG2BOP1
KLHDC3ENSG00000124702.132981.772002488.115200.261004.882203.93900HepG2DAZAP1
KLHDC3ENSG00000124702.131136.374701594.11970-0.488305.238504.33400HepG2DDX21
KLHDC3ENSG00000124702.13257.978601065.56680-2.0463023.7160020.70250HepG2DDX28
KLHDC3ENSG00000124702.134813.778903305.895600.542005.970905.08490HepG2DDX3X
KLHDC3ENSG00000124702.13898.740001407.09670-0.646704.907703.91300HepG2DDX55
KLHDC3ENSG00000124702.131900.887401553.840000.290702.324901.42770HepG2DHX30
KLHDC3ENSG00000124702.13839.214801930.17470-1.2016044.6480042.78340HepG2DKC1
KLHDC3ENSG00000124702.131166.358801518.48740-0.380602.851901.91800HepG2EEF2
KLHDC3ENSG00000124702.131026.141501505.60490-0.553107.280305.67040HepG2EIF3G
KLHDC3ENSG00000124702.131956.044503016.78120-0.625106.470205.49230HepG2EIF4A3
KLHDC3ENSG00000124702.131402.558302937.59790-1.0666013.1537011.72060HepG2EIF4B
KLHDC3ENSG00000124702.131257.504802454.88790-0.9651033.4829031.28880HepG2EIF4G1
KLHDC3ENSG00000124702.133831.937803114.737100.298903.523302.85740HepG2ETF1
KLHDC3ENSG00000124702.131402.756502351.31590-0.745208.398507.13860HepG2FIP1L1
KLHDC3ENSG00000124702.132263.616502998.18500-0.405503.666402.63330HepG2G3BP2
KLHDC3ENSG00000124702.131238.892301613.28320-0.380902.980701.92270HepG2GNB2L1
KLHDC3ENSG00000124702.131454.58110992.706500.551104.630803.81490HepG2GPKOW
KLHDC3ENSG00000124702.132231.074301926.064800.212002.372901.46180HepG2HDGF
KLHDC3ENSG00000124702.131088.973401626.46650-0.578807.203406.23330HepG2HNRNPA1
KLHDC3ENSG00000124702.131505.253301809.14400-0.265301.928301.33760HepG2HNRNPC
KLHDC3ENSG00000124702.132254.302901510.184400.5779012.5613011.18230HepG2HNRNPF
KLHDC3ENSG00000124702.133131.386702266.408700.4663014.1273012.71660HepG2HNRNPL
KLHDC3ENSG00000124702.131495.01870947.366300.658107.201306.24060HepG2HNRNPLL
KLHDC3ENSG00000124702.131277.845801621.92170-0.344003.527302.46270HepG2HNRNPM
KLHDC3ENSG00000124702.131408.471201797.18300-0.351605.270104.45410HepG2HNRNPU
KLHDC3ENSG00000124702.132392.848001487.089600.6861012.4373011.01610HepG2IGF2BP1
KLHDC3ENSG00000124702.131940.811302870.22200-0.564506.068505.10600HepG2IGF2BP2
KLHDC3ENSG00000124702.13862.129601723.21730-0.999106.520204.59910HepG2KHDRBS1
KLHDC3ENSG00000124702.131507.863202887.14040-0.9371011.321709.21780HepG2KHSRP
KLHDC3ENSG00000124702.131274.096001580.68960-0.311102.573601.47830HepG2LARP7
KLHDC3ENSG00000124702.131767.238303045.40700-0.7851010.834109.56110HepG2MAGOH
KLHDC3ENSG00000124702.132290.851103062.36460-0.418803.250702.57090HepG2MATR3
KLHDC3ENSG00000124702.132461.005802908.96950-0.241303.433502.77330HepG2PCBP1
KLHDC3ENSG00000124702.13962.159101721.59200-0.839407.261505.65610HepG2PCBP2
KLHDC3ENSG00000124702.13679.661101084.92110-0.674706.484005.30500HepG2PRPF8
KLHDC3ENSG00000124702.131933.808802959.85960-0.6141013.8230012.78430HepG2PTBP1
KLHDC3ENSG00000124702.131640.479502355.24760-0.521806.714905.83990HepG2PUF60
KLHDC3ENSG00000124702.132021.076803205.86880-0.6656014.7472013.46770HepG2QKI
KLHDC3ENSG00000124702.133084.178802356.331400.388205.086103.96700HepG2RBM15
KLHDC3ENSG00000124702.132213.108802603.31030-0.234302.636002.12750HepG2RBM22
KLHDC3ENSG00000124702.132190.571202909.43080-0.409405.198804.30140HepG2RBM25
KLHDC3ENSG00000124702.131438.507001906.08110-0.406003.634502.49030HepG2RBM27
KLHDC3ENSG00000124702.13948.689401657.53180-0.805006.470903.36180HepG2RBM34
KLHDC3ENSG00000124702.131171.211201547.82450-0.402202.740501.68500HepG2RCC2
KLHDC3ENSG00000124702.132056.783503294.14390-0.6795014.7758013.71160HepG2NELFE
KLHDC3ENSG00000124702.132065.747903067.85800-0.5706012.0699010.91980HepG2RECQL
KLHDC3ENSG00000124702.132228.048001627.002300.453504.661703.80630HepG2RPLP0
KLHDC3ENSG00000124702.13760.398601199.45020-0.657508.471107.46550HepG2RPS19
KLHDC3ENSG00000124702.131187.970901757.86690-0.565306.441805.25140HepG2RPS2
KLHDC3ENSG00000124702.13401.201901073.15850-1.4195017.4979015.83470HepG2RRP9
KLHDC3ENSG00000124702.131952.198803081.82120-0.6587015.8473014.61010HepG2SF3B4
KLHDC3ENSG00000124702.131019.595801866.41830-0.8723032.3083030.51330HepG2SMN1
KLHDC3ENSG00000124702.13546.790701043.32210-0.932103.668502.76430HepG2SNRNP70
KLHDC3ENSG00000124702.131662.910903216.66210-0.9519025.4967024.37780HepG2SRSF1
KLHDC3ENSG00000124702.131438.630201009.067300.511603.619502.45920HepG2SRSF3
KLHDC3ENSG00000124702.131685.940302325.55840-0.464008.759307.72790HepG2SRSF5
KLHDC3ENSG00000124702.132041.874001483.744100.460607.943606.86450HepG2SRSF7
KLHDC3ENSG00000124702.131895.341502616.84680-0.4654010.346609.39830HepG2SRSF9
KLHDC3ENSG00000124702.131735.075902552.75890-0.5571014.3989013.41300HepG2SSB
KLHDC3ENSG00000124702.132064.502502644.71970-0.357305.351004.53740HepG2SUCLG1
KLHDC3ENSG00000124702.13615.535001587.19630-1.3666031.4314028.76050HepG2SUPT6H
KLHDC3ENSG00000124702.131404.928902891.00620-1.0411036.2725034.54060HepG2TAF15
KLHDC3ENSG00000124702.131425.47210923.630300.626007.187106.09510HepG2TARDBP
KLHDC3ENSG00000124702.132140.071202656.71160-0.312003.439302.51100HepG2TIA1
KLHDC3ENSG00000124702.131292.184202011.04940-0.638108.443907.34380HepG2U2AF1
KLHDC3ENSG00000124702.131714.994902435.76910-0.506203.770702.78620HepG2UBE2L3
KLHDC3ENSG00000124702.13647.17290827.26240-0.354202.409301.69970HepG2UCHL5
KLHDC3ENSG00000124702.131433.658001705.02120-0.250102.657502.07050HepG2UTP3
KLHDC3ENSG00000124702.131125.255601634.02020-0.538203.498402.05790HepG2XRCC5
KLHDC3ENSG00000124702.131366.408601827.02350-0.419102.346001.37090HepG2XRCC6
KLHDC3ENSG00000124702.132107.646501700.324100.309704.464003.64260HepG2ZC3H8
KLHDC3ENSG00000124702.132187.815501942.282900.171602.123101.62570HepG2ZNF622
KLHDC3ENSG00000124702.131784.587102274.89180-0.350203.358102.04240K562AARS
KLHDC3ENSG00000124702.135626.932503634.054700.6307022.8692021.35050K562AGGF1
KLHDC3ENSG00000124702.135147.211903993.366300.366104.147602.89090K562AKAP8
KLHDC3ENSG00000124702.135491.417503781.420700.538204.760903.89680K562AKAP8L
KLHDC3ENSG00000124702.133221.036104686.10510-0.540907.492506.60390K562AQR
KLHDC3ENSG00000124702.134859.542803967.662200.292402.940002.00050K562ATP5C1
KLHDC3ENSG00000124702.132984.975204342.82330-0.540909.573507.37870K562CCDC124
KLHDC3ENSG00000124702.131152.347102617.35350-1.1835025.2770021.38690K562DDX28
KLHDC3ENSG00000124702.133364.992703791.01450-0.172001.966801.39980K562DDX47
KLHDC3ENSG00000124702.132975.315602433.019000.290203.648902.09030K562DDX6
KLHDC3ENSG00000124702.131412.908501972.06370-0.481002.710801.71960K562EIF3A
KLHDC3ENSG00000124702.132906.955502188.484200.409506.177304.08730K562EWSR1
KLHDC3ENSG00000124702.131553.209902180.90640-0.489704.070001.97820K562FAM120A
KLHDC3ENSG00000124702.133978.293302715.254800.551007.770206.27780K562FIP1L1
KLHDC3ENSG00000124702.13880.962801672.61850-0.9250010.099308.58750K562G3BP2
KLHDC3ENSG00000124702.132771.063502233.514500.311002.137401.32540K562HNRNPM
KLHDC3ENSG00000124702.134491.118803681.058500.286902.553001.78600K562HSPD1
KLHDC3ENSG00000124702.131334.625201957.56720-0.552605.850103.70310K562KHDRBS1
KLHDC3ENSG00000124702.134930.195004012.955300.296902.860602.01920K562KIF1C
KLHDC3ENSG00000124702.134835.466203841.448300.331903.297302.09260K562MAK16
KLHDC3ENSG00000124702.135351.010704495.534400.251202.488001.63370K562MBNL1
KLHDC3ENSG00000124702.134003.334203628.496100.141702.235301.55760K562NSUN2
KLHDC3ENSG00000124702.134257.805402475.910900.782104.237902.94680K562PABPN1
KLHDC3ENSG00000124702.131644.737702259.62510-0.458203.429302.34040K562PCBP2
KLHDC3ENSG00000124702.134447.897203082.608900.528905.983004.69910K562PPIG
KLHDC3ENSG00000124702.131845.278702383.57080-0.369303.311002.48900K562PRPF8
KLHDC3ENSG00000124702.134569.376505692.94060-0.317202.863602.03380K562PUF60
KLHDC3ENSG00000124702.134848.672106055.65750-0.320704.379403.01120K562PUM1
KLHDC3ENSG00000124702.135083.869905933.01680-0.222802.921401.93640K562PUM2
KLHDC3ENSG00000124702.136232.217803749.974700.7328011.0889010.05130K562PUS1
KLHDC3ENSG00000124702.135589.303103653.915500.6131015.6817014.25220K562RBM15
KLHDC3ENSG00000124702.131761.508702427.57760-0.462703.947502.96860K562RPS19
KLHDC3ENSG00000124702.131434.198802026.14710-0.498504.240603.01630K562SF3B1
KLHDC3ENSG00000124702.132609.287601930.201800.434804.729903.28320K562SRFBP1
KLHDC3ENSG00000124702.133072.360802419.454700.344602.812002.10040K562SRSF1
KLHDC3ENSG00000124702.133023.034902361.733300.356102.755801.94050K562TIA1
KLHDC3ENSG00000124702.133031.107302280.396400.410504.475303.20760K562TRIM56
KLHDC3ENSG00000124702.131142.876401673.96550-0.550608.069706.68590K562U2AF2
KLHDC3ENSG00000124702.133038.553303423.43230-0.172102.208401.44480K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for KLHDC3 is not available on ENCORE database.





7 RBPs can affect the splicing of KLHDC3 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEKLHDC3ENSG00000124702.13chr6+429852564298543342984871429850844298559042985706-0.119000.000000.00000excludedK562SF3B4
SEKLHDC3ENSG00000124702.13chr6+429852564298543342984871429850844298559042985706-0.059000.000030.00217excludedK562PRPF8
SEKLHDC3ENSG00000124702.13chr6+429852564298543342984871429850844298559042985706-0.133000.000000.00006excludedHepG2U2AF1
SEKLHDC3ENSG00000124702.13chr6+429852564298543342984871429850844298559042985706-0.067000.000000.00000excludedK562AQR
SEKLHDC3ENSG00000124702.13chr6+429852564298543342984871429850844298559042985706-0.082000.000030.00111excludedK562U2AF1
SEKLHDC3ENSG00000124702.13chr6+429852564298543342984871429850844298559042985706-0.069000.000120.02413excludedK562HNRNPM
SEKLHDC3ENSG00000124702.13chr6+429852564298549442984871429850844298559042985706-0.105000.002070.03604excludedK562U2AF2
SEKLHDC3ENSG00000124702.13chr6+429852564298543342984871429850844298559042985706-0.090000.001810.06381excludedK562SF3B1
A5SSKLHDC3ENSG00000124702.13chr6+4298525642985494429852564298543342985590429857060.060000.000000.00000longerK562AQR
MXEKLHDC3ENSG00000124702.13chr6+42985590429857064298588242985954429847224298508442986080429862940.084000.000000.000001includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for KLHDC3 is not avaliable on ENCORE database.