GPN3

General Information

Gene Name       : GPN3
Gene ID             : ENSG00000111231.8
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: GPN3)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878GPN3ENSG00000111231.832.0428.8630.45ENCSR000AEF
HepG2GPN3ENSG00000111231.819.7927.7823.79ENCSR985KAT
K562GPN3ENSG00000111231.841.2837.4539.37ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for GPN3 is not avaliable on ENCORE database.



Proteins bound to RNA
  • GPN3 RNA is bound by 5 proteins.  







eCLIP assay for GPN3 is not avaliable on ENCORE database.





5 proteins are bound to GPN3 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr12110890783110890850-3'-UTR,CDS,intron-Distal5.3134012.30838K562YBX3
chr12110890765110890783-3'-UTR,intron-Distal4.401215.79022K562YBX3
chr12110890794110890902-3'-UTR,CDS,intron-Distal3.609796.06436HepG2BCLAF1
chr12110890597110890668-3'-UTR,intron-Distal4.232913.69113K562LIN28B
chr12110905958110906050-5'-UTR,CDS,intron-Distal,intron-Proximal4.3252022.78217K562DDX3X
chr12110902992110903020-5'-UTR,CDS,intron-Distal,intron-Proximal4.4110414.60876K562DDX3X
chr12110905960110906038-5'-UTR,CDS,intron-Distal,intron-Proximal4.083674.00551K562DROSHA
chr12110897584110897671-CDS,intron-Distal,intron-Proximal4.473575.00488K562LIN28B
chr12110902912110902992-CDS,intron-Distal,intron-Proximal3.5309812.24852K562DDX3X
chr12110902909110902990-CDS,intron-Distal,intron-Proximal3.432864.29172K562YBX3
chr12110891554110891599-CDS,intron-Distal,intron-Proximal4.130113.02457HepG2BCLAF1
chr12110891599110891657-CDS,intron-Distal,intron-Proximal4.422593.38968HepG2BCLAF1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for GPN3 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for GPN3 is not available on ENCORE database.

  • 130 RBPs can affect the levels of GPN3.  








The Knockdown/knockout RNA-Seq assay for GPN3 is not available on ENCORE database.





130 RBPs can affect the gene expression of GPN3 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
GPN3ENSG00000111231.4211.83650352.47700-0.734603.960202.84720HepG2ABCF1
GPN3ENSG00000111231.4172.69980407.45050-1.2384016.5692014.90630HepG2AKAP8L
GPN3ENSG00000111231.4254.28510504.41060-0.988208.907807.55200HepG2ASCC1
GPN3ENSG00000111231.4487.92060599.96270-0.298202.136701.51960HepG2AUH
GPN3ENSG00000111231.4160.07370322.69490-1.011406.217504.93360HepG2BCLAF1
GPN3ENSG00000111231.4127.87690227.54240-0.831404.375003.64240HepG2BOP1
GPN3ENSG00000111231.4232.60580479.22980-1.042809.548708.18570HepG2CIRBP
GPN3ENSG00000111231.4190.74630405.46340-1.0879014.2880013.02310HepG2CKAP4
GPN3ENSG00000111231.4122.08490208.89260-0.774903.541402.77370HepG2CPSF6
GPN3ENSG00000111231.4279.60760593.48650-1.0858016.7490015.43430HepG2CELF1
GPN3ENSG00000111231.4246.27900375.05980-0.606805.590504.45720HepG2DDX19B
GPN3ENSG00000111231.478.35380324.51260-2.0502024.4524022.72100HepG2DDX21
GPN3ENSG00000111231.4396.08220583.95600-0.560103.668702.95860HepG2DDX3X
GPN3ENSG00000111231.4129.12080365.08230-1.4995012.1497010.66860HepG2DDX55
GPN3ENSG00000111231.4133.76780237.21410-0.826503.192302.14440HepG2DDX59
GPN3ENSG00000111231.4207.94910387.97710-0.899708.896607.82000HepG2DKC1
GPN3ENSG00000111231.4230.07460348.87180-0.600604.289103.43040HepG2DNAJC21
GPN3ENSG00000111231.4202.51260345.80120-0.771907.302206.31220HepG2DNAJC2
GPN3ENSG00000111231.4169.60220320.47620-0.918105.793404.49990HepG2EEF2
GPN3ENSG00000111231.4183.97740267.16180-0.538202.434401.39670HepG2EFTUD2
GPN3ENSG00000111231.4210.87000482.22700-1.1934011.6498010.48500HepG2EIF2S1
GPN3ENSG00000111231.4159.47550260.15340-0.706003.087302.13720HepG2EIF3D
GPN3ENSG00000111231.4220.89060306.39130-0.472002.469401.44840HepG2EIF3G
GPN3ENSG00000111231.4241.61050532.88010-1.1411010.963009.71870HepG2EIF4A3
GPN3ENSG00000111231.4257.19110518.90490-1.012607.230206.14800HepG2EIF4B
GPN3ENSG00000111231.4480.30200629.57160-0.390403.258902.36430HepG2EIF4G1
GPN3ENSG00000111231.4433.51610603.09380-0.476303.287002.40340HepG2EIF4G2
GPN3ENSG00000111231.4208.87890305.34540-0.547802.611101.54750HepG2ESF1
GPN3ENSG00000111231.4530.36530688.84290-0.377203.134602.50100HepG2ETF1
GPN3ENSG00000111231.4394.38790537.76680-0.447402.517801.85620HepG2FXR1
GPN3ENSG00000111231.4276.31500498.79810-0.852106.778805.75740HepG2G3BP1
GPN3ENSG00000111231.4283.68470529.61590-0.900708.076306.53740HepG2G3BP2
GPN3ENSG00000111231.4121.39950231.63240-0.932105.174903.94610HepG2GEMIN5
GPN3ENSG00000111231.4111.60060236.78600-1.085206.066105.14440HepG2GPKOW
GPN3ENSG00000111231.4162.72540352.21420-1.114008.998607.93080HepG2HNRNPA1
GPN3ENSG00000111231.4223.62240586.48500-1.3910024.8154022.60490HepG2HNRNPA2B1
GPN3ENSG00000111231.4215.52080391.77650-0.862206.460305.43640HepG2HNRNPC
GPN3ENSG00000111231.4202.65240290.81090-0.521103.139202.37870HepG2HNRNPF
GPN3ENSG00000111231.4387.68570581.33530-0.584506.928905.90600HepG2HNRNPL
GPN3ENSG00000111231.492.62310225.97010-1.286707.874006.87310HepG2HNRNPLL
GPN3ENSG00000111231.4202.36920389.18610-0.9435010.244909.14070HepG2HNRNPU
GPN3ENSG00000111231.4183.36310286.36500-0.643203.916003.06680HepG2IGF2BP1
GPN3ENSG00000111231.4202.10970506.99620-1.3268014.6553013.23980HepG2IGF2BP2
GPN3ENSG00000111231.4253.65940397.54010-0.648206.359605.29310HepG2ILF2
GPN3ENSG00000111231.4278.24110509.99110-0.874105.905104.38950HepG2KHSRP
GPN3ENSG00000111231.4214.75030467.62520-1.122709.143907.62720HepG2LARP4
GPN3ENSG00000111231.4290.13230537.95510-0.890807.701906.62270HepG2MAGOH
GPN3ENSG00000111231.4180.95110540.94760-1.5799018.0690016.56830HepG2MATR3
GPN3ENSG00000111231.4162.47600272.27270-0.744802.389001.40770HepG2METAP2
GPN3ENSG00000111231.4154.45270288.07420-0.899305.829604.69800HepG2MSI2
GPN3ENSG00000111231.4281.88290553.67490-0.973908.793007.69820HepG2NCBP2
GPN3ENSG00000111231.4478.10680632.80920-0.404403.221302.40050HepG2NOL12
GPN3ENSG00000111231.4198.61600335.15250-0.754802.608401.54910HepG2NONO
GPN3ENSG00000111231.4229.22040493.01490-1.1049010.665909.26870HepG2PABPC4
GPN3ENSG00000111231.4286.33080385.22340-0.428002.747801.90240HepG2PARN
GPN3ENSG00000111231.4249.05320512.15990-1.0401010.110409.06750HepG2PCBP1
GPN3ENSG00000111231.4214.87670349.19150-0.700503.526802.35980HepG2PCBP2
GPN3ENSG00000111231.4144.53730215.14070-0.573802.626301.42980HepG2PKM
GPN3ENSG00000111231.4238.32920347.12230-0.542503.689402.85060HepG2PPIL4
GPN3ENSG00000111231.4163.75350281.72640-0.782803.768102.84310HepG2PRPF8
GPN3ENSG00000111231.4253.55260521.10720-1.0393014.3824013.32590HepG2PTBP1
GPN3ENSG00000111231.4304.23290604.06370-0.9895011.8264010.71240HepG2PUF60
GPN3ENSG00000111231.4405.52860641.23090-0.661009.411708.45500HepG2PUM1
GPN3ENSG00000111231.4444.94660640.76840-0.526204.644103.78620HepG2PUM2
GPN3ENSG00000111231.4247.62890413.04820-0.738107.537906.60380HepG2PUS1
GPN3ENSG00000111231.4354.54900564.44590-0.670906.646905.73950HepG2QKI
GPN3ENSG00000111231.4379.88560575.74400-0.599905.804005.12230HepG2RBM22
GPN3ENSG00000111231.4304.69510512.24300-0.749507.047606.01130HepG2RBM25
GPN3ENSG00000111231.4299.88580429.18100-0.517202.510001.56920HepG2RBM27
GPN3ENSG00000111231.4123.99280271.52150-1.130803.034201.34140HepG2RBM39
GPN3ENSG00000111231.4264.63570579.97110-1.1320016.4666015.35860HepG2NELFE
GPN3ENSG00000111231.4301.64100540.11200-0.8404010.324909.24970HepG2RECQL
GPN3ENSG00000111231.4186.04150313.28640-0.751904.831903.96240HepG2RPLP0
GPN3ENSG00000111231.4192.99070331.02090-0.778403.942602.81660HepG2RPS10
GPN3ENSG00000111231.490.04000253.14350-1.4913012.6819011.48100HepG2RPS19
GPN3ENSG00000111231.4221.77120395.84250-0.835905.706404.58210HepG2RPS2
GPN3ENSG00000111231.4178.80980283.23640-0.663603.025702.19030HepG2RPS3A
GPN3ENSG00000111231.4190.36410278.69500-0.549901.983101.30650HepG2RRP9
GPN3ENSG00000111231.4119.83760254.06450-1.084107.342005.83040HepG2SERBP1
GPN3ENSG00000111231.4127.78470223.66000-0.807603.931203.10220HepG2SF3B1
GPN3ENSG00000111231.4275.58850542.60200-0.977409.809008.79650HepG2SF3B4
GPN3ENSG00000111231.4437.38260579.18350-0.405103.610902.82670HepG2SLBP
GPN3ENSG00000111231.4264.56940404.17390-0.611305.546204.68650HepG2SMN1
GPN3ENSG00000111231.4209.69480343.61990-0.712503.867002.71870HepG2SMNDC1
GPN3ENSG00000111231.4316.74260650.27970-1.0377017.4195016.44700HepG2SRFBP1
GPN3ENSG00000111231.4290.97690566.33370-0.9607013.1843012.31730HepG2SRSF1
GPN3ENSG00000111231.4331.43320596.41360-0.8476011.6916010.52910HepG2SRSF5
GPN3ENSG00000111231.4208.68790285.71480-0.453202.434401.77860HepG2SRSF7
GPN3ENSG00000111231.4344.14950460.72070-0.420903.355302.75950HepG2SRSF9
GPN3ENSG00000111231.4238.42800564.59320-1.2437021.5974020.46080HepG2SSB
GPN3ENSG00000111231.4385.42960678.29630-0.8154012.9428011.76320HepG2SUCLG1
GPN3ENSG00000111231.4171.10850363.46130-1.086906.792905.80690HepG2SUPV3L1
GPN3ENSG00000111231.4131.50620220.27760-0.744203.477102.67520HepG2TARDBP
GPN3ENSG00000111231.4320.03890467.75100-0.547504.213403.19060HepG2TIA1
GPN3ENSG00000111231.4128.03710378.15450-1.5624018.2988017.22110HepG2TIAL1
GPN3ENSG00000111231.4248.54420381.54830-0.618405.224304.49860HepG2TRIM56
GPN3ENSG00000111231.4386.54870590.12920-0.610405.301304.04950HepG2TUFM
GPN3ENSG00000111231.4174.38030304.47570-0.804104.947304.12130HepG2U2AF1
GPN3ENSG00000111231.499.73100310.68160-1.639305.533304.09380HepG2U2AF2
GPN3ENSG00000111231.4432.10250624.63240-0.531603.202002.30200HepG2UBE2L3
GPN3ENSG00000111231.4132.14060241.98620-0.872906.247105.26640HepG2UPF1
GPN3ENSG00000111231.4211.40900357.78700-0.759104.017903.15290HepG2XRN2
GPN3ENSG00000111231.493.56200266.13850-1.5082016.6185015.55940HepG2ZNF622
GPN3ENSG00000111231.4986.43380749.016800.397104.313803.63240K562AGGF1
GPN3ENSG00000111231.4955.14100779.378600.293301.870301.32870K562AKAP8L
GPN3ENSG00000111231.4884.125001563.97660-0.8229011.2788010.21180K562AQR
GPN3ENSG00000111231.41035.07820817.742000.339903.131002.15600K562ATP5C1
GPN3ENSG00000111231.4692.18250875.43090-0.338803.177802.15280K562BCLAF1
GPN3ENSG00000111231.4335.36540462.48500-0.463702.503901.67610K562BOP1
GPN3ENSG00000111231.4163.14670293.35430-0.846506.066004.33880K562CCAR1
GPN3ENSG00000111231.4340.84560491.76620-0.528903.824002.90230K562CPSF6
GPN3ENSG00000111231.41716.134602312.96330-0.430606.130004.68630K562CELF1
GPN3ENSG00000111231.4227.30320328.38890-0.530802.822101.47960K562DHX30
GPN3ENSG00000111231.41099.32390838.712900.390304.131203.03140K562DKC1
GPN3ENSG00000111231.4522.26170701.06310-0.424802.811901.89080K562EFTUD2
GPN3ENSG00000111231.4811.760401098.05410-0.435805.154504.21630K562EIF2S2
GPN3ENSG00000111231.4175.93150298.40060-0.762203.086802.01740K562EIF3A
GPN3ENSG00000111231.4463.77720755.56600-0.704107.525006.17450K562EIF4A3
GPN3ENSG00000111231.41429.885701880.84940-0.395505.771004.43600K562EIF4G2
GPN3ENSG00000111231.4308.05260500.33730-0.699705.327804.13610K562FMR1
GPN3ENSG00000111231.4285.35810424.07100-0.571503.495302.45940K562FTO
GPN3ENSG00000111231.4314.09500469.52520-0.580003.949903.00620K562GPKOW
GPN3ENSG00000111231.4278.83090673.08710-1.2714018.7337017.25760K562HNRNPC
GPN3ENSG00000111231.4381.03390601.09030-0.657705.671303.95510K562HNRNPF
GPN3ENSG00000111231.4726.49210526.554000.464302.594401.69620K562HNRNPM
GPN3ENSG00000111231.4894.603701185.52900-0.406204.508903.36160K562HNRNPU
GPN3ENSG00000111231.41056.31430827.141000.352702.336001.58700K562KIF1C
GPN3ENSG00000111231.4259.72100400.89100-0.626203.044402.06060K562KRR1
GPN3ENSG00000111231.4479.25690682.71160-0.510503.446701.76890K562LIN28B
GPN3ENSG00000111231.4817.723501015.94870-0.313102.271701.50570K562MAGOH
GPN3ENSG00000111231.4455.502901013.91330-1.1544022.3231019.69290K562MATR3
GPN3ENSG00000111231.4316.05770458.30500-0.536103.688102.66760K562METAP2
GPN3ENSG00000111231.4606.95340778.99160-0.360003.371902.48320K562MTPAP
GPN3ENSG00000111231.4663.94460865.56590-0.382604.618303.68470K562NSUN2
GPN3ENSG00000111231.4467.73230662.75340-0.502803.384201.74550K562NUSAP1
GPN3ENSG00000111231.4460.72090657.15940-0.512404.058602.27670K562PHF6
GPN3ENSG00000111231.4401.79310603.49940-0.586904.288503.12690K562PSIP1
GPN3ENSG00000111231.41765.300002138.63860-0.276803.348702.29120K562PUM2
GPN3ENSG00000111231.41155.86650772.981900.580405.532004.79570K562PUS1
GPN3ENSG00000111231.4998.71330753.111200.407103.977903.28270K562RBM15
GPN3ENSG00000111231.4747.38930946.55050-0.340802.390701.61420K562RBM22
GPN3ENSG00000111231.4375.77160550.64530-0.551304.149202.93370K562RCC2
GPN3ENSG00000111231.4659.94790854.03870-0.371903.536502.62230K562SF3A3
GPN3ENSG00000111231.4311.43100446.50040-0.519702.718101.75260K562SF3B1
GPN3ENSG00000111231.4503.01580817.88310-0.701302.622001.43810K562SNRNP200
GPN3ENSG00000111231.4331.65280521.99390-0.654404.932603.44370K562SRFBP1
GPN3ENSG00000111231.4696.46910874.97620-0.329203.373402.35200K562SRPK2
GPN3ENSG00000111231.4629.00450967.61450-0.621407.290106.15060K562SRSF1
GPN3ENSG00000111231.4464.79350660.49360-0.507003.215602.11710K562SUPV3L1
GPN3ENSG00000111231.4670.78080979.32970-0.546004.928203.96970K562TARDBP
GPN3ENSG00000111231.4347.91210580.46180-0.738505.876304.45940K562TIAL1
GPN3ENSG00000111231.4390.13770616.69940-0.660605.791204.30820K562TRIM56
GPN3ENSG00000111231.4543.61840774.28350-0.510304.995303.91730K562U2AF2
GPN3ENSG00000111231.41802.986402313.95200-0.360003.846002.17950K562UBE2L3
GPN3ENSG00000111231.4458.37620699.07060-0.608904.912303.51540K562UCHL5
GPN3ENSG00000111231.4666.26460917.77500-0.462005.870804.86830K562UPF1
GPN3ENSG00000111231.4620.11390785.31570-0.340702.517201.67960K562WDR3
GPN3ENSG00000111231.4676.46630816.60510-0.271602.439201.64160K562WDR43
GPN3ENSG00000111231.4518.70440711.87990-0.456703.097101.79550K562XRN2
GPN3ENSG00000111231.41332.501901761.90960-0.403003.972702.90610K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for GPN3 is not available on ENCORE database.





5 RBPs can affect the splicing of GPN3 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEGPN3ENSG00000111231.4chr12-1109059601109061801109029901109030191109062761109065240.176000.002020.04764includedHepG2HNRNPK
SEGPN3ENSG00000111231.4chr12-1109059601109061801109029901109030191109062761109065240.204000.000030.00525includedHepG2DDX3X
A3SSGPN3ENSG00000111231.4chr12-1108915471108917381108915471108916761108933901108935050.093000.000000.00000longerK562AQR
A3SSGPN3ENSG00000111231.4chr12-1108933901108935221108933901108934871108936191108937350.061000.000000.00001longerK562AQR
MXEGPN3ENSG00000111231.4chr12-110891547110891676110897499110897667110890293110890901110902910110903019-0.113000.001590.029042includedK562PUS1
MXEGPN3ENSG00000111231.4chr12-1108953141108954391108974991108976671108936191108937351109029101109030190.127000.000440.060691includedK562EIF3G

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for GPN3 is not avaliable on ENCORE database.