GAB1

General Information

Gene Name       : GAB1
Gene ID             : ENSG00000109458.8
Essential Gene : No

Functions

Localization

Domains (AlphaFold: GAB1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878GAB1ENSG00000109458.82.752.552.65ENCSR000AEF
HepG2GAB1ENSG00000109458.89.2310.149.69ENCSR985KAT
K562GAB1ENSG00000109458.88.969.859.41ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for GAB1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • GAB1 RNA is bound by 17 proteins.  







eCLIP assay for GAB1 is not avaliable on ENCORE database.





17 proteins are bound to GAB1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr4144390492144390588+3'-UTR3.684796.24385K562PUM2
chr4144336805144336888+3'-UTR,5'-UTR,CDS4.367284.82934K562RBM15
chr4144257922144258002+5'-UTR4.006073.38582HepG2SRSF7
chr4144257916144257992+5'-UTR4.296228.49253K562TARDBP
chr4144257926144258039+5'-UTR3.785158.84918K562EIF4G2
chr4144257925144257992+5'-UTR3.102383.61506K562NONO
chr4144359509144359599+CDS,intron-Distal4.055643.73331K562RBM15
chr4144270063144270149+intron-Distal4.093494.61322HepG2MATR3
chr4144308727144308885+intron-Distal3.931943.33944K562MATR3
chr4144361139144361220+intron-Distal,intron-Proximal3.720303.02234K562KHSRP
chr4144269944144270124+intron-Distal5.057717.35792K562MATR3
chr4144362855144362967+intron-Distal5.164826.76922HepG2PTBP1
chr4144269218144269293+intron-Distal5.4211210.55162HepG2SUGP2
chr4144259065144259170+intron-Distal4.187793.80512K562CSTF2T
chr4144294159144294275+intron-Distal5.4667210.83979HepG2HNRNPL
chr4144269135144269207+intron-Distal3.068785.68399HepG2SUGP2
chr4144268885144268972+intron-Distal3.435126.05394HepG2SUGP2
chr4144366602144366650+intron-Distal4.214543.01445K562EXOSC5
chr4144286444144286509+intron-Distal5.1195024.02487HepG2QKI
chr4144270162144270221+intron-Distal4.729375.04879HepG2SUGP2
chr4144269710144269764+intron-Distal4.267294.47026K562MATR3
chr4144278776144278832+intron-Distal4.301124.38558HepG2HNRNPM
chr4144378536144378626+intron-Distal4.369003.80778HepG2QKI
chr4144269340144269384+intron-Distal3.012314.61989HepG2SUGP2
chr4144269594144269649+intron-Distal4.957648.31472HepG2SUGP2
chr4144269681144269801+intron-Distal4.1502811.48892HepG2SUGP2
chr4144259035144259158+intron-Distal3.055543.00209K562FUS
chr4144280219144280393+intron-Distal3.753913.43967HepG2TAF15
chr4144299806144299901+intron-Distal4.685569.83693K562PTBP1
chr4144269526144269571+intron-Distal3.829816.02877HepG2SUGP2
chr4144270057144270145+intron-Distal3.9916811.48892HepG2SUGP2
chr4144269292144269393+intron-Distal3.841363.05187HepG2QKI
chr4144279447144279527+intron-Distal3.803353.49011K562KHSRP
chr4144294212144294279+intron-Distal3.980003.82544K562HNRNPL
chr4144269144144269233+intron-Distal4.386374.75674K562MATR3
chr4144299793144299916+intron-Distal4.986986.08961HepG2PTBP1
chr4144366771144366834+intron-Distal4.214543.89080K562EXOSC5
chr4144366486144366566+intron-Distal4.373093.30687K562EXOSC5
chr4144362877144362963+intron-Distal5.017055.05386K562PTBP1
chr4144286417144286512+intron-Distal5.3429125.22515K562QKI
chr4144286509144286563+intron-Distal4.571079.44715HepG2QKI
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for GAB1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for GAB1 is not available on ENCORE database.

  • 111 RBPs can affect the levels of GAB1.  








The Knockdown/knockout RNA-Seq assay for GAB1 is not available on ENCORE database.





111 RBPs can affect the gene expression of GAB1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
GAB1ENSG00000109458.41075.73750840.215300.356402.443901.55870HepG2ABCF1
GAB1ENSG00000109458.4411.24440606.44400-0.560406.404005.55780HepG2ACO1
GAB1ENSG00000109458.4365.16080864.50650-1.2433014.5246013.40410HepG2AKAP1
GAB1ENSG00000109458.4503.57930715.33130-0.506403.403402.53340HepG2ASCC1
GAB1ENSG00000109458.4519.13600833.36060-0.6828010.125008.94850HepG2AUH
GAB1ENSG00000109458.4238.70460515.85360-1.111709.384307.60810HepG2BCCIP
GAB1ENSG00000109458.4439.96160813.69670-0.8871010.741109.66290HepG2BOP1
GAB1ENSG00000109458.4425.20130606.28060-0.511805.647504.75840HepG2CKAP4
GAB1ENSG00000109458.4229.26080459.37270-1.002706.405005.24090HepG2CNOT7
GAB1ENSG00000109458.4586.47060747.01690-0.349102.005501.40960HepG2CPSF6
GAB1ENSG00000109458.4465.13870694.75280-0.578806.614405.70210HepG2CELF1
GAB1ENSG00000109458.4508.31720747.08080-0.555507.764506.61330HepG2DAZAP1
GAB1ENSG00000109458.4673.80270512.914000.393502.566301.90930HepG2DDX21
GAB1ENSG00000109458.4635.87430501.870000.341302.103201.31770HepG2DDX24
GAB1ENSG00000109458.4261.17220384.23810-0.557003.052801.58440HepG2DDX28
GAB1ENSG00000109458.4438.16810828.18500-0.918509.712008.60140HepG2DDX3X
GAB1ENSG00000109458.4218.98460507.18610-1.2117010.896709.48280HepG2DDX55
GAB1ENSG00000109458.4388.27720711.30300-0.873407.561506.58480HepG2DDX6
GAB1ENSG00000109458.4846.98050580.194400.545706.803005.83060HepG2DKC1
GAB1ENSG00000109458.4402.02340523.97370-0.382202.676401.98140HepG2DNAJC21
GAB1ENSG00000109458.4320.62740519.35710-0.695808.812607.72700HepG2DNAJC2
GAB1ENSG00000109458.4340.98570505.65580-0.568403.231702.03460HepG2EFTUD2
GAB1ENSG00000109458.4333.49050683.91690-1.0362011.020209.88440HepG2EIF2S1
GAB1ENSG00000109458.4305.63770492.36080-0.687903.372302.37930HepG2EIF3D
GAB1ENSG00000109458.4988.71870728.028900.441503.814102.54440HepG2ESF1
GAB1ENSG00000109458.4260.46980439.95740-0.756205.910104.16270HepG2FAM120A
GAB1ENSG00000109458.4338.90770488.75950-0.528203.815302.50230HepG2FASTKD2
GAB1ENSG00000109458.4599.94290848.47700-0.500102.494401.75950HepG2FIP1L1
GAB1ENSG00000109458.4290.14380721.57710-1.314404.775103.33320HepG2FUS
GAB1ENSG00000109458.4435.42490707.38720-0.700105.662904.72480HepG2G3BP1
GAB1ENSG00000109458.41216.95240846.799300.523104.091403.32550HepG2GPKOW
GAB1ENSG00000109458.4557.40320686.56400-0.300702.191601.34990HepG2HNRNPA2B1
GAB1ENSG00000109458.4414.84950716.07060-0.787507.629406.51380HepG2HNRNPK
GAB1ENSG00000109458.4437.12600680.54890-0.638609.055507.90300HepG2HNRNPL
GAB1ENSG00000109458.41027.73000808.116400.346702.212701.64320HepG2HNRNPLL
GAB1ENSG00000109458.4372.81010584.52050-0.648807.699806.72570HepG2HNRNPU
GAB1ENSG00000109458.4479.26260597.06770-0.317102.513601.81120HepG2ILF2
GAB1ENSG00000109458.4716.21750982.16210-0.455602.665001.84990HepG2LARP4
GAB1ENSG00000109458.4288.58790558.62850-0.952909.854507.84910HepG2LARP7
GAB1ENSG00000109458.4435.32660586.67840-0.430502.463601.32410HepG2LIN28B
GAB1ENSG00000109458.4463.14110767.02190-0.727805.768404.88370HepG2MATR3
GAB1ENSG00000109458.4309.18180515.33250-0.737002.727801.68370HepG2METAP2
GAB1ENSG00000109458.4553.96510785.11360-0.503103.334702.64110HepG2NCBP2
GAB1ENSG00000109458.4526.72440740.80100-0.492004.893403.88330HepG2NOL12
GAB1ENSG00000109458.41112.48620716.551600.634506.411205.30060HepG2NSUN2
GAB1ENSG00000109458.4413.47430578.57090-0.484704.478203.43060HepG2PARN
GAB1ENSG00000109458.4451.05170680.37500-0.593007.222606.31730HepG2PCBP1
GAB1ENSG00000109458.4777.02310600.531500.371603.503302.64340HepG2PRPF4
GAB1ENSG00000109458.4539.54380692.28120-0.359602.894602.33790HepG2PTBP1
GAB1ENSG00000109458.4485.53590750.64930-0.628609.570708.60660HepG2PUM1
GAB1ENSG00000109458.4617.57730750.11130-0.280501.873501.31570HepG2PUM2
GAB1ENSG00000109458.4778.18780617.697900.333103.153602.50520HepG2PUS1
GAB1ENSG00000109458.4707.06490925.26200-0.388003.368402.43050HepG2RBM15
GAB1ENSG00000109458.4649.69640799.71450-0.299702.220001.74230HepG2RBM22
GAB1ENSG00000109458.4482.31210673.60000-0.481902.774201.78040HepG2RBM27
GAB1ENSG00000109458.4283.29140479.04580-0.757905.468704.63650HepG2RPS19
GAB1ENSG00000109458.4438.59960621.26460-0.502303.119902.27010HepG2RPS2
GAB1ENSG00000109458.4444.41110634.14730-0.512903.171902.01620HepG2RPS5
GAB1ENSG00000109458.4204.97630387.06140-0.917106.054404.93890HepG2RRP9
GAB1ENSG00000109458.4387.06220520.53930-0.427403.595302.87820HepG2SAFB2
GAB1ENSG00000109458.4541.83490720.80030-0.411703.909803.22700HepG2SF3B4
GAB1ENSG00000109458.4302.37840607.03340-1.0054017.6430016.23120HepG2SMN1
GAB1ENSG00000109458.4340.73940671.26670-0.978203.850602.70620HepG2SMNDC1
GAB1ENSG00000109458.4592.90000903.24880-0.607309.117508.35250HepG2SRFBP1
GAB1ENSG00000109458.4629.02070860.67160-0.452402.505801.55670HepG2SRSF3
GAB1ENSG00000109458.4546.23630698.18300-0.354103.062102.40730HepG2SRSF5
GAB1ENSG00000109458.4510.01520612.05290-0.263101.940101.46220HepG2SRSF9
GAB1ENSG00000109458.41490.56280784.235100.9264026.4921025.26890HepG2SSB
GAB1ENSG00000109458.4466.29430794.04350-0.7680012.8922011.71450HepG2SUCLG1
GAB1ENSG00000109458.4195.39210338.42470-0.792504.763203.50610HepG2TFIP11
GAB1ENSG00000109458.4285.57010573.04900-1.0048015.7773014.58400HepG2TRIM56
GAB1ENSG00000109458.4124.54390298.26810-1.2600010.243108.78510HepG2UCHL5
GAB1ENSG00000109458.4592.39890846.02080-0.514106.829705.81200HepG2UPF1
GAB1ENSG00000109458.4533.17400816.80000-0.615408.338207.38890HepG2UTP3
GAB1ENSG00000109458.4709.27000930.46110-0.391605.039104.35560HepG2ZNF622
GAB1ENSG00000109458.4522.69230671.69580-0.361802.954001.96450K562BCLAF1
GAB1ENSG00000109458.4961.235001409.01440-0.551709.174607.16950K562CPEB4
GAB1ENSG00000109458.4876.932601330.45360-0.601407.894306.55580K562CPSF6
GAB1ENSG00000109458.42587.531001899.806100.445606.197304.74680K562CELF1
GAB1ENSG00000109458.4356.83870525.77200-0.559204.589003.19810K562DDX3X
GAB1ENSG00000109458.42206.859201458.281900.5976013.5695012.23590K562DDX47
GAB1ENSG00000109458.4412.99550533.04940-0.368102.667401.39350K562DDX6
GAB1ENSG00000109458.4912.702401116.11640-0.290302.486501.66240K562DKC1
GAB1ENSG00000109458.41140.08560652.698200.804607.837005.72930K562EEF2
GAB1ENSG00000109458.4448.72820630.72670-0.491202.673701.77730K562EFTUD2
GAB1ENSG00000109458.4394.000701038.84740-1.3987027.5598025.69760K562EIF2S2
GAB1ENSG00000109458.4921.55150431.626301.094208.673906.85630K562EIF3A
GAB1ENSG00000109458.41020.48350675.472700.595204.871403.45210K562EIF3D
GAB1ENSG00000109458.4725.29250533.613600.442703.908702.97180K562EIF3G
GAB1ENSG00000109458.42213.017801545.450500.517904.300803.13740K562EIF4G2
GAB1ENSG00000109458.4865.850301353.76570-0.644807.627506.16500K562FMR1
GAB1ENSG00000109458.4748.739201147.46490-0.615905.827504.44890K562FTO
GAB1ENSG00000109458.4756.08170571.223900.404403.586002.91130K562FXR1
GAB1ENSG00000109458.4761.42680569.830100.418102.169401.55420K562G3BP2
GAB1ENSG00000109458.4845.718301384.49250-0.711106.043804.92070K562GRSF1
GAB1ENSG00000109458.41285.46760731.698400.8129013.4240011.34220K562HNRNPA1
GAB1ENSG00000109458.4603.816001181.14490-0.968002.350801.49610K562HNRNPM
GAB1ENSG00000109458.4853.885601947.60640-1.189603.151702.30520K562HSPD1
GAB1ENSG00000109458.4736.748901239.89750-0.7510010.540808.75110K562METAP2
GAB1ENSG00000109458.41298.295101647.36810-0.343502.395401.34760K562MSI2
GAB1ENSG00000109458.4417.67670548.51920-0.393202.673201.46590K562NCBP2
GAB1ENSG00000109458.41257.257501020.987100.300203.814502.95390K562NSUN2
GAB1ENSG00000109458.4558.38230733.08670-0.392703.101101.66890K562PCBP1
GAB1ENSG00000109458.4518.44630667.33880-0.364202.208801.33940K562PCBP2
GAB1ENSG00000109458.41883.278901165.402900.692306.867605.55510K562PCBP3
GAB1ENSG00000109458.4584.56840801.75930-0.455803.119301.45820K562PKM
GAB1ENSG00000109458.41310.99770893.867600.552405.803504.64710K562POLR2G
GAB1ENSG00000109458.4814.097501630.15030-1.001702.655001.85560K562PPIG
GAB1ENSG00000109458.4330.12630574.29270-0.798807.441705.81830K562PSIP1
GAB1ENSG00000109458.4394.90070728.67310-0.8838012.3193010.97090K562PTBP1
GAB1ENSG00000109458.41111.164801757.39270-0.661406.486204.99990K562PUM2
GAB1ENSG00000109458.4588.493401028.62010-0.805609.527308.56870K562PUS1
GAB1ENSG00000109458.4511.12490698.76170-0.451103.379202.44500K562RBM22
GAB1ENSG00000109458.4720.99120525.555400.456004.786102.70770K562RPS10
GAB1ENSG00000109458.4814.01890625.302300.380402.253501.51970K562RPS19
GAB1ENSG00000109458.42002.003401225.990000.707405.062202.84150K562RPS3A
GAB1ENSG00000109458.4894.61520628.964100.508203.724702.54120K562RPS3
GAB1ENSG00000109458.4875.72690627.672600.480402.878001.52130K562RRP9
GAB1ENSG00000109458.41238.98240796.571100.637207.921906.12880K562SAFB
GAB1ENSG00000109458.41440.41980823.511600.8065011.304008.59140K562SDAD1
GAB1ENSG00000109458.4908.931801208.12590-0.410502.763301.79000K562SF3B1
GAB1ENSG00000109458.41443.701301032.057300.484108.696307.13730K562SRPK2
GAB1ENSG00000109458.4391.76470714.33200-0.8666010.696109.31540K562SRSF1
GAB1ENSG00000109458.4525.31070674.60670-0.360902.268701.33500K562SRSF5
GAB1ENSG00000109458.41375.726901017.394800.435203.516401.78680K562SRSF9
GAB1ENSG00000109458.4529.39300697.38340-0.397602.979702.12560K562TIA1
GAB1ENSG00000109458.4722.74650552.372200.387702.291601.44580K562TIAL1
GAB1ENSG00000109458.4530.73430684.28680-0.366602.401101.39780K562TRA2A
GAB1ENSG00000109458.4800.30350570.471700.488304.787403.73400K562U2AF2
GAB1ENSG00000109458.4814.684001082.56950-0.410104.644203.73830K562UPF1
GAB1ENSG00000109458.4981.097301301.75720-0.408002.779401.57480K562UTP3
GAB1ENSG00000109458.41737.68530963.220100.8511011.9949010.37410K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for GAB1 is not available on ENCORE database.





11 RBPs can affect the splicing of GAB1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEGAB1ENSG00000109458.4chr4+144378832144378922144361231144361535144380537144380582-0.313000.000760.01669excludedK562SF3B4
SEGAB1ENSG00000109458.4chr4+144378832144378922144361231144361535144380537144380582-0.246000.001100.03403excludedK562AKAP8L
SEGAB1ENSG00000109458.4chr4+144378832144378922144361231144361535144380537144380582-0.196000.000410.05501excludedHepG2HNRNPM
SEGAB1ENSG00000109458.4chr4+144378832144378922144361231144361535144380537144380582-0.275000.000000.00000excludedHepG2U2AF2
SEGAB1ENSG00000109458.4chr4+144378832144378922144361231144361535144380537144380582-0.278000.006910.07933excludedK562PUS1
SEGAB1ENSG00000109458.4chr4+144378832144378922144361325144361535144380537144380631-0.304000.001920.03839excludedK562U2AF1
SEGAB1ENSG00000109458.4chr4+144378832144378922144361231144361535144380537144380582-0.176000.000330.01279excludedHepG2SF3A3
SEGAB1ENSG00000109458.4chr4+144378832144378922144361231144361535144380537144380582-0.264000.000000.00015excludedHepG2RBFOX2
SEGAB1ENSG00000109458.4chr4+144378832144378922144361325144361535144380537144380631-0.245000.001190.03898excludedK562UTP18
SEGAB1ENSG00000109458.4chr4+144378832144378922144361325144361535144380537144380631-0.399000.000000.00009excludedK562HNRNPU
SEGAB1ENSG00000109458.4chr4+144378832144378922144361231144361535144380537144380582-0.284000.000060.00298excludedK562AGGF1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for GAB1 is not avaliable on ENCORE database.