CYP27A1

General Information

Gene Name       : CYP27A1
Gene ID             : ENSG00000135929.8
Essential Gene : No

Functions

Localization

Domains (AlphaFold: CYP27A1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878CYP27A1ENSG00000135929.80.020.150.08ENCSR000AEF
HepG2CYP27A1ENSG00000135929.8186.16112.35149.25ENCSR985KAT
K562CYP27A1ENSG00000135929.80.060.010.03ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for CYP27A1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • CYP27A1 RNA is bound by 25 proteins.  







eCLIP assay for CYP27A1 is not avaliable on ENCORE database.





25 proteins are bound to CYP27A1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr2219677618219677679+3'-UTR,CDS,intron-Proximal3.508178.96944HepG2PRPF8
chr2219679923219679965+3'-UTR3.899065.48237HepG2G3BP1
chr2219679656219679755+3'-UTR,CDS3.177659.78656HepG2G3BP1
chr2219677679219677732+3'-UTR,CDS3.5012415.00953HepG2RPS3
chr2219677465219677518+3'-UTR,CDS,intron-Proximal4.2998719.55694HepG2PRPF8
chr2219677735219677813+3'-UTR,CDS4.6303515.34471HepG2RPS3
chr2219677300219677333+3'-UTR,CDS3.157399.07906HepG2RPS3
chr2219679802219679822+3'-UTR4.1781316.57230HepG2LARP4
chr2219678743219678860+3'-UTR,CDS,intron-Proximal3.3174514.28770HepG2SND1
chr2219679918219679957+3'-UTR4.131676.53253HepG2DDX55
chr2219677467219677514+3'-UTR,CDS,intron-Proximal3.2579110.31786HepG2AQR
chr2219679769219679802+3'-UTR4.4274919.81730HepG2LARP4
chr2219679699219679889+3'-UTR,CDS3.150295.22257HepG2UPF1
chr2219679648219679757+3'-UTR,CDS3.5755220.53526HepG2DDX55
chr2219679915219679960+3'-UTR4.5696920.26411HepG2LARP4
chr2219677733219677801+3'-UTR,CDS3.5081214.30552HepG2PPIG
chr2219679822219679870+3'-UTR4.5361019.12150HepG2LARP4
chr2219677660219677712+3'-UTR,CDS3.057694.74492HepG2LIN28B
chr2219677386219677431+3'-UTR,CDS3.6964915.03648HepG2RPS3
chr2219677264219677306+3'-UTR,CDS,intron-Proximal3.836775.89850HepG2AQR
chr2219677580219677701+3'-UTR,CDS,intron-Proximal3.2164514.24861HepG2AQR
chr2219679700219679769+3'-UTR,CDS4.6444326.88439HepG2LARP4
chr2219677052219677097+3'-UTR,CDS3.2500910.96198HepG2RPS3
chr2219677807219677858+3'-UTR,CDS,intron-Proximal3.698956.76873HepG2AQR
chr2219646507219646551+5'-UTR4.7898811.01276HepG2DDX3X
chr2219646729219646769+5'-UTR4.681279.60311HepG2DDX3X
chr2219679284219679358+CDS4.0267122.89630HepG2RPS3
chr2219679272219679318+CDS3.316906.40070HepG2G3BP1
chr2219678900219678956+CDS,intron-Proximal4.9445919.80783HepG2PRPF8
chr2219647011219647075+CDS4.0192424.54631HepG2DDX3X
chr2219676999219677011+CDS4.204194.25741HepG2G3BP1
chr2219679611219679668+CDS,intron-Proximal5.8530112.86303HepG2AQR
chr2219646907219647011+CDS5.0316487.35887HepG2DDX3X
chr2219679030219679124+CDS,intron-Proximal3.6982119.69297HepG2EFTUD2
chr2219678803219678858+CDS4.4196216.61784HepG2RPS3
chr2219674438219674467+CDS,intron-Distal3.763476.02304HepG2GRWD1
chr2219676979219677021+CDS3.7403811.98919HepG2SND1
chr2219647139219647204+CDS,intron-Proximal3.6688821.87115HepG2PRPF8
chr2219676944219676979+CDS,intron-Proximal3.5068213.26570HepG2SND1
chr2219679056219679122+CDS,intron-Proximal4.009097.44609HepG2AQR
chr2219679102219679136+CDS,intron-Proximal3.137555.88048HepG2G3BP1
chr2219646933219647008+CDS4.5033320.67578HepG2RPS3
chr2219679282219679359+CDS3.9119723.73330HepG2LARP4
chr2219679322219679372+CDS3.999668.77191HepG2G3BP1
chr2219679640219679691+CDS3.4035914.26416HepG2LARP4
chr2219678905219678911+CDS,intron-Proximal3.300875.44144HepG2RPS3
chr2219679405219679452+CDS3.7992912.04042HepG2RPS3
chr2219679406219679452+CDS4.5431715.14481HepG2LARP4
chr2219679281219679357+CDS3.8391917.86341HepG2DDX55
chr2219679277219679329+CDS5.260085.16101HepG2PCBP1
chr2219649084219649136+intron-Distal5.537038.16423HepG2U2AF2
chr2219649522219649594+intron-Distal4.6086725.34746HepG2CSTF2
chr2219673758219673819+intron-Distal3.713573.10834HepG2CSTF2
chr2219648554219648616+intron-Distal4.923257.14580HepG2TAF15
chr2219649536219649593+intron-Distal4.6642711.39119HepG2CSTF2T
chr2219648812219648874+intron-Distal3.409864.35278HepG2TAF15
chr2219648712219648812+intron-Distal4.082678.85914HepG2TAF15
chr2219658450219658529+intron-Distal4.091724.51536HepG2HNRNPC
chr2219649337219649397+intron-Distal4.628456.41805HepG2KHSRP
chr2219647424219647494+intron-Distal3.310926.50351HepG2TAF15
chr2219650029219650106+intron-Distal4.088793.20552HepG2KHSRP
chr2219669326219669384+intron-Distal3.204825.59399HepG2SUGP2
chr2219678163219678227+intron-Distal3.767023.21162HepG2HNRNPC
chr2219649205219649270+intron-Distal3.682694.97118HepG2U2AF2
chr2219649109219649164+intron-Distal4.267513.75546HepG2KHSRP
chr2219679514219679577+intron-Proximal5.2150415.18793HepG2AQR
chr2219679008219679072+intron-Proximal3.192913.60305HepG2SF3B4
chr2219677186219677225+intron-Proximal4.310676.87873HepG2EFTUD2
chr2219679212219679261+intron-Proximal4.060563.74254HepG2SF3B4
chr2219679524219679568+intron-Proximal3.893933.25631HepG2PRPF4
chr2219679048219679089+intron-Proximal4.748119.75742HepG2BUD13
chr2219677158219677232+intron-Proximal3.547645.55742HepG2PRPF4
chr2219679027219679091+intron-Proximal3.290706.04937HepG2PRPF4
chr2219678965219679027+intron-Proximal3.086874.60395HepG2PRPF4
chr2219679551219679592+intron-Proximal4.271674.61506HepG2EFTUD2
chr2219678910219678946+intron-Proximal4.663765.90930HepG2AQR
chr2219678973219679013+intron-Proximal3.858098.82330HepG2EFTUD2
chr2219677525219677566+intron-Proximal4.391516.11036HepG2XPO5
chr2219677529219677567+intron-Proximal4.017355.93840HepG2PRPF8
chr2219677225219677271+intron-Proximal5.0641510.21769HepG2EFTUD2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for CYP27A1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for CYP27A1 is not available on ENCORE database.

  • 107 RBPs can affect the levels of CYP27A1.  








The Knockdown/knockout RNA-Seq assay for CYP27A1 is not available on ENCORE database.





107 RBPs can affect the gene expression of CYP27A1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
CYP27A1ENSG00000135929.41458.612802082.02810-0.513404.741203.37170HepG2AATF
CYP27A1ENSG00000135929.45595.015203124.346200.8405013.2944011.49110HepG2ABCF1
CYP27A1ENSG00000135929.41422.685502487.60960-0.8061010.863209.82400HepG2ACO1
CYP27A1ENSG00000135929.42490.180001604.458300.634105.673104.31430HepG2ADAR
CYP27A1ENSG00000135929.41389.941906754.90950-2.2809072.2295070.11690HepG2AKAP1
CYP27A1ENSG00000135929.42856.217103476.96860-0.283704.112303.30570HepG2AUH
CYP27A1ENSG00000135929.43045.723401888.783000.689204.914003.74600HepG2BCLAF1
CYP27A1ENSG00000135929.42003.421101350.394200.569006.998206.09560HepG2BOP1
CYP27A1ENSG00000135929.48727.943005309.886000.7169011.360309.89760HepG2CIRBP
CYP27A1ENSG00000135929.43610.995602486.581700.5381012.8893011.66680HepG2CKAP4
CYP27A1ENSG00000135929.41220.185602445.93450-1.003305.431004.35640HepG2CNOT7
CYP27A1ENSG00000135929.41739.336101239.705800.488404.797803.91330HepG2CPSF6
CYP27A1ENSG00000135929.41304.586202132.62170-0.709003.558801.94170HepG2CSTF2T
CYP27A1ENSG00000135929.42396.124703017.41520-0.332604.710003.91140HepG2CELF1
CYP27A1ENSG00000135929.43241.711602300.458500.494706.085004.91680HepG2DDX19B
CYP27A1ENSG00000135929.42063.868801647.595700.324902.602601.48040HepG2DDX1
CYP27A1ENSG00000135929.45141.680406470.13340-0.331602.657502.04320HepG2DDX3X
CYP27A1ENSG00000135929.44380.531303238.807300.435505.168803.43410HepG2DDX47
CYP27A1ENSG00000135929.41539.370202137.81660-0.473802.381201.65780HepG2DDX55
CYP27A1ENSG00000135929.47398.300505559.294400.412203.337902.66650HepG2DDX6
CYP27A1ENSG00000135929.42993.942001558.214500.9421020.3384018.12350HepG2DHX30
CYP27A1ENSG00000135929.45011.676002379.842301.0743055.5981053.57730HepG2DKC1
CYP27A1ENSG00000135929.42199.262001615.514200.444905.089204.16120HepG2DNAJC21
CYP27A1ENSG00000135929.41874.234901601.471900.226802.157601.56820HepG2DNAJC2
CYP27A1ENSG00000135929.43491.293602065.711800.7570011.614009.90260HepG2EEF2
CYP27A1ENSG00000135929.42199.183705342.97850-1.2807029.5215027.72530HepG2EIF2S1
CYP27A1ENSG00000135929.41287.305001676.81370-0.381402.736101.83800HepG2EIF3D
CYP27A1ENSG00000135929.42678.012902168.450800.304403.196402.04290HepG2EIF3G
CYP27A1ENSG00000135929.48200.360305903.987500.473904.190003.40770HepG2EIF4A3
CYP27A1ENSG00000135929.42503.936705749.56630-1.1993017.5797015.94710HepG2EIF4B
CYP27A1ENSG00000135929.43893.254303200.812700.282404.992203.92230HepG2EIF4G1
CYP27A1ENSG00000135929.42739.600703992.05320-0.5432015.1272013.90310HepG2ETF1
CYP27A1ENSG00000135929.41192.800101498.82120-0.329503.267401.98460HepG2FAM120A
CYP27A1ENSG00000135929.41262.602403154.67360-1.3211023.1712021.34420HepG2FIP1L1
CYP27A1ENSG00000135929.42659.155701779.179800.579704.121702.59480HepG2FKBP4
CYP27A1ENSG00000135929.41644.169102362.58070-0.523002.593001.51090HepG2FUS
CYP27A1ENSG00000135929.44338.531405958.78780-0.457804.711103.82430HepG2FXR1
CYP27A1ENSG00000135929.42364.141605526.64370-1.2251025.0486023.11890HepG2G3BP1
CYP27A1ENSG00000135929.43526.946801405.221701.3275027.3607025.58380HepG2GPKOW
CYP27A1ENSG00000135929.41541.624502264.56510-0.554802.868201.73510HepG2GRSF1
CYP27A1ENSG00000135929.43281.894801630.993701.0087015.2855013.96640HepG2HNRNPA1
CYP27A1ENSG00000135929.43430.107101814.253100.9188019.8195018.12950HepG2HNRNPC
CYP27A1ENSG00000135929.42813.120001887.155200.5759013.9003012.45430HepG2HNRNPF
CYP27A1ENSG00000135929.43737.825705598.57540-0.582908.498307.32660HepG2HNRNPK
CYP27A1ENSG00000135929.42956.732601341.036301.1406023.4855021.94060HepG2HNRNPLL
CYP27A1ENSG00000135929.42536.690203421.08660-0.431502.686901.47920HepG2HSPD1
CYP27A1ENSG00000135929.44117.274401858.301601.1476037.7179035.52140HepG2IGF2BP1
CYP27A1ENSG00000135929.41847.480605273.08600-1.513109.656407.91020HepG2IGF2BP3
CYP27A1ENSG00000135929.43139.385902273.684100.465408.368406.67080HepG2KIF1C
CYP27A1ENSG00000135929.43842.021705993.92800-0.641607.410706.41650HepG2MATR3
CYP27A1ENSG00000135929.41315.015901754.87730-0.416302.451301.45860HepG2METAP2
CYP27A1ENSG00000135929.42672.528802143.480500.318202.772001.55520HepG2NAA15
CYP27A1ENSG00000135929.43917.788506134.86570-0.647008.169007.10780HepG2NCBP2
CYP27A1ENSG00000135929.42306.719603216.83910-0.479807.114005.90060HepG2NOL12
CYP27A1ENSG00000135929.42340.151401189.144200.9766014.1665012.61520HepG2NSUN2
CYP27A1ENSG00000135929.44607.548802236.157501.042906.667805.24570HepG2PABPC1
CYP27A1ENSG00000135929.44420.393005462.33650-0.305302.248001.59210HepG2PABPC4
CYP27A1ENSG00000135929.41032.638601783.82900-0.788609.856208.42370HepG2PARN
CYP27A1ENSG00000135929.43850.775005778.17290-0.5855017.4503016.13680HepG2PCBP1
CYP27A1ENSG00000135929.43217.339002193.864700.552303.313701.65260HepG2PNPT1
CYP27A1ENSG00000135929.42421.698401607.452600.591107.528806.35700HepG2PPIL4
CYP27A1ENSG00000135929.42544.788602158.857900.237202.976302.17810HepG2PRPF4
CYP27A1ENSG00000135929.43089.768905879.37980-0.9282044.2768042.64420HepG2PTBP1
CYP27A1ENSG00000135929.47008.821103070.861701.1904039.0742037.15620HepG2PUF60
CYP27A1ENSG00000135929.42062.208203259.98070-0.6607016.0016014.81620HepG2PUM1
CYP27A1ENSG00000135929.44245.771602533.720500.7447019.0276017.67290HepG2PUS1
CYP27A1ENSG00000135929.43146.857406367.78450-1.0169039.6410037.76960HepG2QKI
CYP27A1ENSG00000135929.41007.558203336.61190-1.7275091.9991089.83320HepG2RBM22
CYP27A1ENSG00000135929.44022.952005779.07130-0.522608.920207.76190HepG2RBM25
CYP27A1ENSG00000135929.41751.868202420.41210-0.466402.385101.47230HepG2RBM27
CYP27A1ENSG00000135929.42862.234901965.492900.542203.908702.64450HepG2RCC2
CYP27A1ENSG00000135929.43968.893406543.29090-0.7213012.4841011.48940HepG2NELFE
CYP27A1ENSG00000135929.43270.298106093.99450-0.8980044.5326042.66160HepG2RECQL
CYP27A1ENSG00000135929.43226.796802033.041900.6664010.426909.24730HepG2RPLP0
CYP27A1ENSG00000135929.42923.651202120.515000.463302.716301.78040HepG2RPS10
CYP27A1ENSG00000135929.41065.450601631.70200-0.614908.749107.72900HepG2RPS19
CYP27A1ENSG00000135929.41624.666502278.66610-0.488002.288901.31700HepG2RPS5
CYP27A1ENSG00000135929.42085.746901604.942200.377905.688404.81690HepG2SAFB2
CYP27A1ENSG00000135929.42119.078601637.527200.371803.055302.06540HepG2SERBP1
CYP27A1ENSG00000135929.42174.812801327.314100.7123010.171208.89590HepG2SF3B1
CYP27A1ENSG00000135929.43459.966606121.42130-0.8231037.6844035.97350HepG2SF3B4
CYP27A1ENSG00000135929.44217.308002944.735200.5181019.0231017.49330HepG2SLBP
CYP27A1ENSG00000135929.41538.520101871.56010-0.282702.183801.60120HepG2SMN1
CYP27A1ENSG00000135929.42181.932703768.57010-0.7884034.2804033.03260HepG2SRFBP1
CYP27A1ENSG00000135929.44427.874306389.34550-0.5291018.6423017.64310HepG2SRSF1
CYP27A1ENSG00000135929.42907.821101854.093800.6491017.7660016.27390HepG2SRSF7
CYP27A1ENSG00000135929.411076.108503271.993001.75910184.62080182.29260HepG2SSB
CYP27A1ENSG00000135929.42888.862903448.29410-0.255404.015903.29110HepG2SUCLG1
CYP27A1ENSG00000135929.42689.327502129.558900.336603.104602.11340HepG2SUPT6H
CYP27A1ENSG00000135929.43085.332102127.864300.535902.551801.89920HepG2SUPV3L1
CYP27A1ENSG00000135929.42743.825705742.73450-1.0655025.1078023.64840HepG2TAF15
CYP27A1ENSG00000135929.41685.002501307.311000.366003.010402.25830HepG2TARDBP
CYP27A1ENSG00000135929.43395.911705277.06480-0.6359013.2202011.42260HepG2TIA1
CYP27A1ENSG00000135929.44837.609301750.947201.4661066.6585064.81850HepG2TIAL1
CYP27A1ENSG00000135929.42236.806401766.898000.340104.695604.00010HepG2TRIM56
CYP27A1ENSG00000135929.45185.739003067.426400.7574033.4740031.60580HepG2UPF1
CYP27A1ENSG00000135929.43481.277301947.683700.837807.293305.60840HepG2UPF2
CYP27A1ENSG00000135929.42208.696302961.47800-0.423108.800907.83050HepG2UTP3
CYP27A1ENSG00000135929.41146.267602122.70460-0.889005.685003.87610HepG2XRCC5
CYP27A1ENSG00000135929.41367.812002373.18760-0.795005.181403.75640HepG2XRCC6
CYP27A1ENSG00000135929.45066.614702094.658101.2742027.1948025.06520HepG2XRN2
CYP27A1ENSG00000135929.42594.806102130.487200.284304.978504.12180HepG2ZC3H8
CYP27A1ENSG00000135929.40.4794012.92440-4.752703.054702.20750K562MTPAP
CYP27A1ENSG00000135929.42.2183014.17110-2.675402.133001.40990K562SF3A3
CYP27A1ENSG00000135929.40.4866014.51890-4.899103.723402.65680K562SRPK2
CYP27A1ENSG00000135929.40.3903015.22380-5.285604.141003.27960K562UPF1
CYP27A1ENSG00000135929.40.5334013.02620-4.610003.257502.31210K562WDR3
CYP27A1ENSG00000135929.40.5156013.54800-4.715703.579502.62470K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for CYP27A1 is not available on ENCORE database.





1 RBPs can affect the splicing of CYP27A1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SECYP27A1ENSG00000135929.4chr2+219674299219674490219646471219647160219676944219677144-0.115000.000000.00000excludedHepG2SRSF1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for CYP27A1 is not avaliable on ENCORE database.