CBLB

General Information

Gene Name       : CBLB
Gene ID             : ENSG00000114423.20
Essential Gene : No

Functions

Localization

Domains (AlphaFold: CBLB)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878CBLBENSG00000114423.2032.6431.5232.08ENCSR000AEF
HepG2CBLBENSG00000114423.204.867.386.12ENCSR985KAT
K562CBLBENSG00000114423.204.273.964.12ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for CBLB is not avaliable on ENCORE database.



Proteins bound to RNA
  • CBLB RNA is bound by 14 proteins.  







eCLIP assay for CBLB is not avaliable on ENCORE database.





14 proteins are bound to CBLB RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr3105452839105452985-3'-UTR,CDS,intron-Distal,intron-Proximal4.551124.67689HepG2PPIG
chr3105464759105464885-3'-UTR,CDS,intron-Distal,intron-Proximal3.328048.84415HepG2BCLAF1
chr3105456019105456098-3'-UTR,CDS,intron-Distal3.796396.81385HepG2BCLAF1
chr3105587716105587856-5'-UTR,intron-Distal5.027326.92972HepG2NCBP2
chr3105586362105586428-5'-UTR,CDS,intron-Distal3.274864.74886HepG2BCLAF1
chr3105495245105495391-CDS,intron-Distal,intron-Proximal3.673529.67260HepG2BCLAF1
chr3105495329105495403-CDS,intron-Distal,intron-Proximal3.232164.28417K562U2AF2
chr3105572257105572340-CDS,intron-Distal,intron-Proximal3.593117.74581HepG2BCLAF1
chr3105470369105470464-CDS,intron-Distal,intron-Proximal4.319365.79432HepG2BCLAF1
chr3105495330105495409-CDS,intron-Distal,intron-Proximal3.740343.62357HepG2U2AF2
chr3105389127105389205-CDS,intron-Distal,intron-Proximal4.367623.77802HepG2U2AF2
chr3105412392105412486-CDS,intron-Distal,intron-Proximal4.861685.40008K562SF3B4
chr3105586249105586273-CDS,intron-Distal,intron-Proximal3.316194.69916HepG2SRSF1
chr3105572435105572510-CDS,intron-Distal,intron-Proximal4.8353711.54096HepG2BCLAF1
chr3105586253105586354-CDS,intron-Distal,intron-Proximal5.031786.16445HepG2PPIG
chr3105551582105551740-intron-Distal3.342754.30460HepG2HNRNPL
chr3105491291105491347-intron-Distal4.164734.03915HepG2SUGP2
chr3105547704105547758-intron-Distal3.346093.55754HepG2U2AF2
chr3105496895105497013-intron-Distal4.182858.46806K562HNRNPL
chr3105491293105491338-intron-Distal3.575774.31711K562EXOSC5
chr3105487171105487298-intron-Distal3.304794.61989HepG2SUGP2
chr3105491660105491702-intron-Distal4.394493.59917K562EXOSC5
chr3105489328105489379-intron-Distal3.873543.29248HepG2SUGP2
chr3105558187105558275-intron-Distal4.218803.55640HepG2QKI
chr3105483731105483827-intron-Distal3.804798.60624HepG2SUGP2
chr3105572013105572098-intron-Distal4.394393.73609HepG2KHSRP
chr3105496872105496959-intron-Distal5.4667210.83979HepG2HNRNPL
chr3105473293105473377-intron-Distal3.980074.89779HepG2PTBP1
chr3105408782105408936-intron-Distal4.051783.66668K562KHSRP
chr3105488419105488466-intron-Distal3.946833.16028HepG2SUGP2
chr3105530046105530139-intron-Distal5.602048.73280K562QKI
chr3105546427105546508-intron-Distal3.050695.24728HepG2U2AF2
chr3105546422105546512-intron-Distal3.337373.19404HepG2PTBP1
chr3105490300105490390-intron-Distal5.7540111.99536K562EXOSC5
chr3105572098105572220-intron-Distal,intron-Proximal3.195495.27624HepG2KHSRP
chr3105496850105496981-intron-Distal3.424997.75673K562AGGF1
chr3105458531105458617-intron-Distal3.076403.19404HepG2PTBP1
chr3105514068105514135-intron-Distal3.776053.68839K562KHSRP
chr3105536352105536416-intron-Distal3.212093.84025HepG2SUGP2
chr3105404006105404081-intron-Distal,intron-Proximal4.359094.12401HepG2U2AF2
chr3105546545105546618-intron-Distal3.793723.02234K562KHSRP
chr3105572094105572202-intron-Distal,intron-Proximal3.839834.56635K562KHSRP
chr3105490765105490822-intron-Distal4.926556.73731K562EXOSC5
chr3105483343105483432-intron-Distal3.214507.46148HepG2SUGP2
chr3105491425105491497-intron-Distal3.749735.20902K562EXOSC5
chr3105478706105478731-intron-Distal4.325733.59917K562EXOSC5
chr3105551888105551977-intron-Distal4.227453.97888HepG2HNRNPL
chr3105536269105536352-intron-Distal3.662155.78794HepG2SUGP2
chr3105470189105470273-intron-Distal,intron-Proximal4.555733.09122HepG2PTBP1
chr3105536250105536421-intron-Distal4.217854.49973K562MATR3
chr3105389689105389790-intron-Distal5.023068.32953HepG2QKI
chr3105490152105490194-intron-Distal3.618214.91094K562EXOSC5
chr3105558291105558348-intron-Distal3.916834.36528HepG2U2AF2
chr3105530056105530137-intron-Distal4.571075.05488HepG2QKI
chr3105547831105547895-intron-Distal4.616374.64001HepG2U2AF2
chr3105490567105490638-intron-Distal4.8435511.58120K562EXOSC5
chr3105398937105399044-intron-Distal4.029483.97888HepG2HNRNPL
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for CBLB is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for CBLB is not available on ENCORE database.

  • 96 RBPs can affect the levels of CBLB.  








The Knockdown/knockout RNA-Seq assay for CBLB is not available on ENCORE database.





96 RBPs can affect the gene expression of CBLB :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
CBLBENSG00000114423.14637.24800482.866900.400102.529401.50190HepG2AATF
CBLBENSG00000114423.14604.74580791.02780-0.387402.367201.49430HepG2ABCF1
CBLBENSG00000114423.14586.46960781.98380-0.415102.210201.72850HepG2AKAP1
CBLBENSG00000114423.14812.16290570.428600.509606.148705.04790HepG2AKAP8L
CBLBENSG00000114423.141180.99890769.923800.6171010.678809.47590HepG2AUH
CBLBENSG00000114423.14635.93510382.794400.732206.431805.12330HepG2BCLAF1
CBLBENSG00000114423.141015.57950564.664500.8467011.2291010.13090HepG2BOP1
CBLBENSG00000114423.14873.95830592.547900.560505.298403.62150HepG2BUD13
CBLBENSG00000114423.141381.17960687.554401.0063021.0231019.26080HepG2CALR
CBLBENSG00000114423.14676.08330969.91470-0.520703.252502.19040HepG2CCAR1
CBLBENSG00000114423.14903.15540567.652500.6699011.8784010.69590HepG2CKAP4
CBLBENSG00000114423.14777.42310518.403000.584505.091804.18430HepG2CPSF6
CBLBENSG00000114423.14990.12480651.292800.604206.253504.64440HepG2CPSF7
CBLBENSG00000114423.14427.11130525.07140-0.297902.183501.43630HepG2DDX19B
CBLBENSG00000114423.14393.57670532.81110-0.437002.790102.10990HepG2DDX21
CBLBENSG00000114423.14568.09380749.07770-0.399002.329801.75060HepG2DDX3X
CBLBENSG00000114423.141371.64160588.681301.2202010.514508.69450HepG2DDX59
CBLBENSG00000114423.141038.05930643.481800.689805.865304.99550HepG2DDX6
CBLBENSG00000114423.14409.66560548.01890-0.419802.272601.43540HepG2EEF2
CBLBENSG00000114423.14604.01870456.817600.402902.324601.31050HepG2EFTUD2
CBLBENSG00000114423.141461.75810618.586101.2406020.7090019.18780HepG2EIF2S1
CBLBENSG00000114423.14593.76690444.846200.416502.265501.44020HepG2EIF3D
CBLBENSG00000114423.14381.91550503.11950-0.397602.517501.48650HepG2EIF3G
CBLBENSG00000114423.141154.00700732.410500.6558011.308109.84330HepG2EIF4G1
CBLBENSG00000114423.14730.15200554.810800.396102.975902.11260HepG2EWSR1
CBLBENSG00000114423.14746.15720507.722800.555305.047303.57290HepG2FASTKD2
CBLBENSG00000114423.141145.68470798.719900.520303.492302.63420HepG2FIP1L1
CBLBENSG00000114423.14520.88340689.74260-0.405102.335601.69780HepG2FXR1
CBLBENSG00000114423.14334.45990529.89280-0.663902.675201.67510HepG2GNB2L1
CBLBENSG00000114423.14729.38370542.033500.428204.571403.34320HepG2HDGF
CBLBENSG00000114423.14911.50890682.281400.417804.481703.34220HepG2HNRNPA2B1
CBLBENSG00000114423.14695.09170530.220600.390503.415102.62450HepG2HNRNPF
CBLBENSG00000114423.14869.23020647.902000.423902.993002.26750HepG2HNRNPK
CBLBENSG00000114423.141067.40970560.829500.9284011.9271010.73690HepG2HNRNPLL
CBLBENSG00000114423.14914.43430650.371700.491503.559902.80340HepG2IGF2BP2
CBLBENSG00000114423.141186.32110610.355200.958702.455801.53580HepG2IGF2BP3
CBLBENSG00000114423.14775.02740601.956400.364504.113303.23650HepG2ILF2
CBLBENSG00000114423.14911.60230571.912200.672504.171002.96650HepG2MTPAP
CBLBENSG00000114423.14904.60510542.735900.736908.777706.67250HepG2NAA15
CBLBENSG00000114423.141411.58740846.492800.737603.937102.86500HepG2PABPC1
CBLBENSG00000114423.141159.40350632.458800.8742010.376209.00100HepG2PABPC4
CBLBENSG00000114423.14884.72070591.879700.579808.115807.16630HepG2PCBP1
CBLBENSG00000114423.141243.26510830.521100.581903.211201.57390HepG2PNPT1
CBLBENSG00000114423.14453.63630334.238300.440602.685501.88910HepG2PRPF8
CBLBENSG00000114423.14820.11760602.269600.445304.641903.97370HepG2PTBP1
CBLBENSG00000114423.14444.46100702.72900-0.660906.505505.64340HepG2PUF60
CBLBENSG00000114423.14814.76500578.241800.494606.302005.44040HepG2PUS1
CBLBENSG00000114423.14913.32150652.251800.485603.992103.26110HepG2QKI
CBLBENSG00000114423.141598.17240933.072200.7763014.5162012.79340HepG2RBM15
CBLBENSG00000114423.14963.20210738.851700.382503.425602.86640HepG2RBM22
CBLBENSG00000114423.141189.74230591.968401.0070018.1140016.48630HepG2RBM25
CBLBENSG00000114423.14730.72330571.206500.355202.077201.47550HepG2RPLP0
CBLBENSG00000114423.14651.63670930.14320-0.513403.078102.23580HepG2RPS3A
CBLBENSG00000114423.14788.95750330.649501.2545016.0016014.39160HepG2RRP9
CBLBENSG00000114423.14767.65520555.126500.467503.553802.76310HepG2SF3B1
CBLBENSG00000114423.14910.31570627.022700.537706.872306.00650HepG2SF3B4
CBLBENSG00000114423.14405.89120611.99880-0.592407.287706.32040HepG2SMN1
CBLBENSG00000114423.14838.68960617.669800.441202.039701.37360HepG2SNRNP70
CBLBENSG00000114423.141988.22740834.498901.2524053.1225051.65030HepG2SRFBP1
CBLBENSG00000114423.14917.11140597.272300.618604.283203.00890HepG2SRSF3
CBLBENSG00000114423.14864.08340520.930900.730008.865107.73830HepG2SRSF7
CBLBENSG00000114423.14961.98740532.463100.8532017.8640016.68460HepG2SRSF9
CBLBENSG00000114423.14733.94830533.377300.460402.761301.52550HepG2STAU1
CBLBENSG00000114423.14819.66830561.732200.545102.757201.55630HepG2SUB1
CBLBENSG00000114423.14912.26920539.226600.758509.182107.55020HepG2SUPT6H
CBLBENSG00000114423.14783.67980546.561200.519802.949702.20410HepG2TARDBP
CBLBENSG00000114423.14889.76560540.541700.718908.246506.81130HepG2TIA1
CBLBENSG00000114423.14366.59300572.59680-0.643306.100405.41050HepG2TIAL1
CBLBENSG00000114423.141266.20010683.181700.8901011.4200010.11880HepG2U2AF1
CBLBENSG00000114423.141330.89050726.670000.872909.507607.91370HepG2UBE2L3
CBLBENSG00000114423.14583.97510753.89480-0.368503.054502.32890HepG2UPF1
CBLBENSG00000114423.14536.20900727.85590-0.440904.473903.74160HepG2UTP3
CBLBENSG00000114423.14285.73760424.39870-0.570701.995101.37160HepG2XRN2
CBLBENSG00000114423.141752.43720829.140001.0796044.9073043.39430HepG2ZNF622
CBLBENSG00000114423.14805.62520632.925000.348003.044102.08680K562ATP5C1
CBLBENSG00000114423.14660.42990477.242300.468602.735601.31460K562CKAP4
CBLBENSG00000114423.14319.54120236.569800.433602.338301.66820K562EIF2S2
CBLBENSG00000114423.14311.26440202.333900.621302.650901.63890K562EIF3D
CBLBENSG00000114423.14367.04930245.940700.577603.175601.95160K562FKBP4
CBLBENSG00000114423.14337.26490238.135500.502003.235301.77580K562FUS
CBLBENSG00000114423.14188.41550353.15750-0.906408.127007.15870K562FXR1
CBLBENSG00000114423.14589.74620371.897700.665104.724603.69200K562GPKOW
CBLBENSG00000114423.14221.07480315.22240-0.511802.672001.92810K562GRSF1
CBLBENSG00000114423.14394.38480283.323500.477102.687002.09750K562HNRNPC
CBLBENSG00000114423.14179.33440278.91060-0.637202.933001.97150K562HNRNPM
CBLBENSG00000114423.14671.45730317.643701.079809.680507.82070K562KRR1
CBLBENSG00000114423.14429.00650274.332200.645004.678902.79990K562LARP7
CBLBENSG00000114423.14333.57330430.80100-0.369002.124601.38390K562MAGOH
CBLBENSG00000114423.14328.95270429.94670-0.386302.216901.39890K562MATR3
CBLBENSG00000114423.14450.98860339.088200.411302.543601.36750K562NCBP2
CBLBENSG00000114423.14519.33200393.615600.399802.012001.30380K562PCBP3
CBLBENSG00000114423.14253.40080418.54050-0.723906.317505.34870K562PTBP1
CBLBENSG00000114423.14280.52410187.316800.582502.488001.71480K562RPS19
CBLBENSG00000114423.14660.25690393.537600.746402.469501.36140K562SF1
CBLBENSG00000114423.14663.66770353.812200.907407.043005.44680K562SF3B1
CBLBENSG00000114423.14737.67380452.028300.706502.635301.44850K562SNRNP200
CBLBENSG00000114423.14606.19970394.830400.618507.204205.76970K562SRPK2
CBLBENSG00000114423.14263.64280410.29470-0.638104.490103.59360K562SRSF1
CBLBENSG00000114423.14357.95700259.556600.463602.397001.52560K562TRIM56
CBLBENSG00000114423.14323.71810188.443100.780504.823603.43800K562UCHL5
CBLBENSG00000114423.14663.86020414.102200.680808.973507.77130K562UPF1
CBLBENSG00000114423.14556.79100354.333100.651905.952804.64330K562WDR3
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for CBLB is not available on ENCORE database.





10 RBPs can affect the splicing of CBLB :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SECBLBENSG00000114423.14chr3-105400322105400454105397274105397415105400567105400662-0.351000.000110.01154excludedHepG2RBM22
SECBLBENSG00000114423.14chr3-1054003221054004541053972741053974151054005671054006620.133000.002720.04660includedHepG2U2AF1
SECBLBENSG00000114423.14chr3-105400322105400454105397274105397415105400567105400662-0.171000.000330.03213excludedHepG2TBRG4
SECBLBENSG00000114423.14chr3-1054003221054004541053972741053974151054005671054006620.248000.000000.00000includedHepG2U2AF2
SECBLBENSG00000114423.14chr3-105400322105400454105397274105397415105400567105400662-0.309000.000480.04677excludedHepG2SRSF7
SECBLBENSG00000114423.14chr3-1054003221054004541053972741053974151054005671054006620.129000.000810.09094includedK562LARP4
SECBLBENSG00000114423.14chr3-1054003221054004541053972741053974151054005671054006620.163000.000070.00972includedK562HNRNPUL1
SECBLBENSG00000114423.14chr3-1054003221054004541053972741053974151054005671054006620.199000.000000.00095includedHepG2RBFOX2
SECBLBENSG00000114423.14chr3-1054003221054004541053972741053974151054005671054006620.144000.000280.05425includedK562NPM1
MXECBLBENSG00000114423.14chr3-105400322105400454105400567105400662105397274105397415105404163105404310-0.331000.000180.002072includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for CBLB is not avaliable on ENCORE database.