CAST

General Information

Gene Name       : CAST
Gene ID             : ENSG00000153113.23
Essential Gene : No

Functions

Localization

Domains (AlphaFold: CAST)


Antibody Validation

 View validation images for all CAST antibodies

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878CASTENSG00000153113.2387.3595.3991.37ENCSR000AEF
HepG2CASTENSG00000153113.2340.5057.6649.08ENCSR985KAT
K562CASTENSG00000153113.2383.5491.6287.58ENCSR000AEO

Assays

1 Released experiments are available on ENCORE database.

Assay TypeExp_NameENCODE IDTarget labelBiosampleStatusLinked AntibodyControlsMethodNote
knockdown followed by RNA-seq CAST-BGKcLV26-K562ENCSR159HPDCASTK562ReleasedENCSR900GQL   CRISPRKD% = 78.8,86.4






  eCLIP  

No eCLIP experiment available



  Antibody Validation  
  GeneName    Antibody_DCC_ID    Product_ID    Lot_ID    Phosphate    HepG2 Primary Validation    K562 Primary Validation    HepG2 Secondary Validation    K562 Secondary Validation  
CASTENCAB248JEGA304-794A1Released, ENCODE4BGKcLV26-59, Released, ENCODE4
CASTENCAB206XCHA301-295A1Released, ENCODE4
CASTENCAB930NNFA304-793A1Released, ENCODE4


  KD RNA-Seq  
  GeneName    Cell_Line    Method    Exp_ID    Control_ID    Sample_reps    Control_reps    KD%    Status    Project    Note  
CASTK562CRISPRENCSR159HPDENCSR900GQLCAST-BGKcLV26-59,CAST-BGKcLV26-60NT-BGKcLV26-1,NT-BGKcLV26-278.8,86.4ReleasedENCODE4
CASTHepG2CRISPRBGHcLV27-41,BGHcLV27-42BGHcLV27-1,BGHcLV27-20.0,0.0NotSatisfiedENCODE4


  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela
CASTProduct_ID: A301-295A
Lot_ID: 1
Source: Bethyl Labs
Target Name: CAST-human		 Bethyl_A301-295A_1_CD3EAP.png<br>Caption: IP-WB analysis of K562 whole cell lysate using the CD3EAP specific antibody, A301-295A. Lanes 1 and 2 are 2.5% of five million whole cell lysate input and 50% of IP enrichment, respectively, using a normal IgG antibody. Lane 3 is 50% of IP enrichment from five million whole cell lysate using the CD3EAP-specific antibody, A301-295A. The same antibody was used to detect protein levels via Western blot. This antibody passes preliminary validation and will be further pursued for secondary validation. *NOTE* Protein sizes are taken from Genecards.org and are only estimates based on sequence. Actual protein size may differ based on protein characteristics and electrophoresis method used.
CASTProduct_ID: A304-793A
Lot_ID: 1
Source: Bethyl Labs
Target Name: CAST-human		 Bethyl_A304-793A_1_CAST.png<br>Caption: IP-WB analysis of K562 whole cell lysate using the CAST specific antibody, A304-793A. Lanes 1 and 2 are 2.5% of five million whole cell lysate input and 50% of IP enrichment, respectively, using a normal IgG antibody. Lane 3 is 50% of IP enrichment from five million whole cell lysate using the CAST-specific antibody, A304-793A. The same antibody was used to detect protein levels via Western blot. This antibody passes preliminary validation and will be further pursued for secondary validation. *NOTE* Protein sizes are taken from Genecards.org and are only estimates based on sequence. Actual protein size may differ based on protein characteristics and electrophoresis method used.
CASTProduct_ID: A304-794A
Lot_ID: 1
Source: Bethyl Labs
Target Name: CAST-human		 Bethyl_A304-794A_1_CAST.png<br>Caption: IP-WB analysis of K562 whole cell lysate using the CAST specific antibody, A304-794A. Lanes 1 and 2 are 2.5% of five million whole cell lysate input and 50% of IP enrichment, respectively, using a normal IgG antibody. Lane 3 is 50% of IP enrichment from five million whole cell lysate using the CAST-specific antibody, A304-794A. The same antibody was used to detect protein levels via Western blot. This antibody passes preliminary validation and will be further pursued for secondary validation. *NOTE* Protein sizes are taken from Genecards.org and are only estimates based on sequence. Actual protein size may differ based on protein characteristics and electrophoresis method used.
 CAST-K562-CRISPR-A304-794A.png<br>Caption: Western blot following CRISPR against CAST in K562 whole cell lysate using CAST specific antibody. Lane 1 is a ladder, lane 2 is K562 non-targeting control knockdown, lane 3 and 4 are two different CRISPR against CAST. CAST protein appears as the green arrow, GAPDH serves as a control and appears in red arrow.








RNA Targets

  • eCLIP assay for CAST is not avaliable on ENCORE database.



Proteins bound to RNA
  • CAST RNA is bound by 23 proteins.  







eCLIP assay for CAST is not avaliable on ENCORE database.





23 proteins are bound to CAST RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr59610834296108427+3'-UTR,intron-Proximal3.7759111.53232HepG2BCLAF1
chr59610880096108882+3'-UTR,intron-Distal,intron-Proximal3.060383.68882K562FAM120A
chr59610738196107407+3'-UTR,intron-Proximal3.121523.24717K562ZNF800
chr59610855996108595+3'-UTR,intron-Proximal4.406384.34038HepG2BCLAF1
chr59610737096107390+3'-UTR,CDS3.204154.62864K562ZNF622
chr59606648396066558+3'-UTR,CDS,intron-Distal,intron-Proximal4.318344.72754K562YBX3
chr59610843496108534+3'-UTR,polyA_site3.789245.10069HepG2GRWD1
chr59605834296058401+3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.141267.26251HepG2GRWD1
chr59605834496058402+3'-UTR,5'-UTR,CDS,intron-Distal3.046647.17439HepG2BCLAF1
chr59610834596108438+3'-UTR3.499544.40421K562MTPAP
chr59605834296058400+3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.6984610.47889K562UCHL5
chr59610834396108410+3'-UTR,intron-Proximal3.227699.38233K562ZNF622
chr59605834296058379+3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal4.3717610.01513K562YBX3
chr59610842696108505+3'-UTR3.186615.76422K562UCHL5
chr59605834296058403+3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.015819.38144K562ZNF622
chr59606650096066564+3'-UTR,CDS,intron-Distal3.574594.56058HepG2BCLAF1
chr59606651696066553+3'-UTR,CDS,intron-Distal4.267143.87995K562UCHL5
chr59610875896108828+3'-UTR,intron-Distal3.851567.00860K562TIA1
chr59610842796108527+3'-UTR,polyA_site3.276508.02162HepG2BCLAF1
chr59610734796107405+3'-UTR,CDS,intron-Proximal4.287225.04143K562GRWD1
chr59603156896031608+5'-UTR,CDS3.636073.12746HepG2GRWD1
chr59607791896078001+5'-UTR,intron-Distal,intron-Proximal3.749776.36410K562DDX3X
chr59601125696011304+5'-UTR,CDS3.810033.12746HepG2GRWD1
chr59603858296038619+5'-UTR,intron-Distal3.881555.57819K562UCHL5
chr59608635596086387+CDS,intron-Proximal4.126107.27704K562ZNF622
chr59609315796093198+CDS3.478707.93794HepG2BCLAF1
chr59608634096086387+CDS,intron-Proximal4.704286.03821HepG2GRWD1
chr59609328496093359+CDS,intron-Proximal3.391534.15543HepG2HLTF
chr59608629096086345+CDS,intron-Proximal3.376329.33743HepG2BCLAF1
chr59607704896077062+CDS4.321403.71613K562UCHL5
chr59609314696093199+CDS,intron-Proximal3.4145912.57224K562UCHL5
chr59609330696093348+CDS5.130116.58593HepG2BCLAF1
chr59607354996073574+CDS,intron-Proximal3.349957.30210K562ZNF622
chr59607578696075823+CDS,intron-Proximal4.054104.46864HepG2BCLAF1
chr59606319196063235+CDS,intron-Distal,intron-Proximal3.737866.39464HepG2BCLAF1
chr59607699296077048+CDS3.496856.43326K562UCHL5
chr59607357596073647+CDS3.495998.19608K562ZNF800
chr59608424496084319+CDS,intron-Proximal4.3139817.96214HepG2BCLAF1
chr59607364296073652+CDS,intron-Proximal4.248657.27704K562ZNF622
chr59607356996073652+CDS,intron-Proximal4.7552313.79295HepG2GRWD1
chr59608422196084244+CDS,intron-Proximal5.202328.06523K562UCHL5
chr59609328996093352+CDS3.870376.62597HepG2GRWD1
chr59610360996103698+CDS,intron-Proximal3.9265211.44223K562ZNF800
chr59608629096086325+CDS,intron-Proximal3.384566.50573K562ZNF800
chr59608204496082113+CDS,intron-Distal,intron-Proximal4.223045.35703HepG2BCLAF1
chr59607574096075749+CDS,intron-Proximal3.8760310.35753HepG2BCLAF1
chr59608628796086348+CDS,intron-Proximal5.1163012.06844K562PUM1
chr59610314196103180+CDS,intron-Proximal4.909626.29310K562ZNF622
chr59609798196098058+CDS4.6593513.88979HepG2GRWD1
chr59609041396090446+CDS,intron-Proximal3.083939.39465K562ZNF800
chr59609314796093199+CDS,intron-Proximal3.634314.14811HepG2FXR2
chr59608976496089837+CDS4.431034.69071HepG2GRWD1
chr59609329496093352+CDS4.127123.79199HepG2PPIG
chr59607697396077007+CDS4.554085.85983HepG2GRWD1
chr59608206596082124+CDS,intron-Distal4.091503.79347HepG2GRWD1
chr59608305496083097+CDS,intron-Proximal4.152284.45558HepG2GRWD1
chr59607700396077062+CDS3.621467.59700K562ZNF622
chr59606319496063235+CDS,intron-Distal,intron-Proximal3.778324.22563K562UCHL5
chr59610364496103704+CDS,intron-Proximal3.418195.31971K562IGF2BP1
chr59608634696086387+CDS,intron-Proximal3.992003.88696K562GRWD1
chr59609328796093306+CDS3.512874.09885HepG2BCLAF1
chr59608304896083097+CDS,intron-Proximal3.181166.91872HepG2BCLAF1
chr59609041896090448+CDS,intron-Proximal4.452036.84316HepG2BCLAF1
chr59606491196064993+CDS,intron-Distal,intron-Proximal5.374888.34710K562AQR
chr59610175796101814+CDS3.250265.91405HepG2BCLAF1
chr59609314696093157+CDS,intron-Proximal3.130115.79926HepG2BCLAF1
chr59607574996075786+CDS4.3925811.55000HepG2BCLAF1
chr59609041296090446+CDS,intron-Proximal3.773803.47312HepG2FXR2
chr59608421996084244+CDS,intron-Proximal5.026886.58593HepG2BCLAF1
chr59610092596101014+CDS,intron-Proximal3.034406.87969HepG2GRWD1
chr59607358696073698+CDS,intron-Proximal4.906526.69228HepG2PRPF8
chr59609798696098077+CDS,intron-Proximal3.222393.72388HepG2FXR2
chr59607355296073565+CDS,intron-Proximal3.428104.22563K562UCHL5
chr59607574196075770+CDS,intron-Proximal4.319617.60776K562ZNF622
chr59606527696065346+CDS,intron-Distal,intron-Proximal3.810835.83621K562AQR
chr59607357996073638+CDS3.753128.59266K562GRWD1
chr59606317096063234+CDS,intron-Distal,intron-Proximal3.727574.18806HepG2U2AF2
chr59608629096086355+CDS,intron-Proximal4.4684121.13832K562ZNF622
chr59607355396073652+CDS,intron-Proximal3.718863.40366HepG2UCHL5
chr59609315596093199+CDS,intron-Proximal3.238853.80498K562PUM1
chr59608628996086353+CDS,intron-Proximal4.146896.90188HepG2ZNF800
chr59608422096084319+CDS,intron-Proximal3.0597815.55524K562ZNF800
chr59609328696093350+CDS,intron-Proximal3.289646.46814K562ZNF622
chr59608634596086386+CDS4.122554.76554HepG2BCLAF1
chr59609036096090408+CDS,intron-Proximal3.6135810.14758K562ZNF622
chr59609040596090453+CDS,intron-Proximal4.147443.49332HepG2PPIG
chr59607189796071944+CDS,intron-Distal4.063203.56019HepG2GRWD1
chr59607697196077042+CDS3.232823.62547K562MTPAP
chr59607363696073653+CDS,intron-Proximal4.6179813.76815HepG2BCLAF1
chr59608628896086346+CDS,intron-Proximal3.069333.26789K562YBX3
chr59609317996093199+CDS,intron-Proximal3.784735.83654K562ZNF622
chr59607719896077284+CDS5.0279412.34367K562UCHL5
chr59607574196075775+CDS,intron-Proximal4.193017.79539K562UCHL5
chr59606485896064903+CDS,intron-Distal3.741304.93978HepG2BCLAF1
chr59610092396101012+CDS,intron-Proximal3.483626.50677K562UCHL5
chr59607700496077051+CDS3.609796.06436HepG2BCLAF1
chr59607355096073648+CDS,intron-Proximal3.010536.53620K562PUM1
chr59609798096098076+CDS3.366979.03739K562UCHL5
chr59608429796084318+CDS,intron-Proximal3.2529810.93472K562ZNF622
chr59608425496084318+CDS,intron-Proximal4.222578.95271K562PUM1
chr59607357496073636+CDS3.4534915.80944HepG2BCLAF1
chr59610361396103702+CDS3.436677.52043HepG2GRWD1
chr59608976396089785+CDS,intron-Proximal4.909626.29310K562ZNF622
chr59608983496089866+CDS,intron-Proximal4.837624.70478HepG2BCLAF1
chr59609036096090446+CDS,intron-Proximal3.6810818.97774K562UCHL5
chr59610363296103701+CDS3.068984.24005HepG2BCLAF1
chr59607696896077004+CDS,intron-Proximal3.238725.40132HepG2BCLAF1
chr59607190996071942+CDS,intron-Distal4.572655.50697K562UCHL5
chr59609040896090446+CDS,intron-Proximal3.0224010.89712K562ZNF622
chr59608422096084244+CDS,intron-Proximal3.930533.79347HepG2GRWD1
chr59607189496071945+CDS,intron-Distal,intron-Proximal3.580345.97823HepG2BCLAF1
chr59608628896086378+CDS,intron-Proximal4.7732725.43760K562UCHL5
chr59608976196089834+CDS,intron-Proximal4.228305.65086HepG2BCLAF1
chr59608984296089867+CDS,intron-Proximal4.222087.87612K562UCHL5
chr59608426396084319+CDS,intron-Proximal4.6295816.75438K562UCHL5
chr59608628996086346+CDS,intron-Proximal3.367867.26180K562GRWD1
chr59609036196090446+CDS,intron-Proximal3.655334.06415K562TRA2A
chr59609314696093198+CDS,intron-Proximal3.8143313.14110K562ZNF800
chr59608429196084318+CDS,intron-Proximal3.042576.85184K562GRWD1
chr59607696896076973+CDS,intron-Proximal4.139044.04622HepG2GRWD1
chr59610362196103701+CDS3.951758.82687K562UCHL5
chr59610363596103703+CDS4.848125.34770HepG2IGF2BP1
chr59609314796093198+CDS,intron-Proximal3.545373.05161HepG2PPIG
chr59610322096103287+intron-Distal,intron-Proximal4.916115.69951K562AQR
chr59595249495952557+intron-Distal3.933163.50031HepG2HNRNPL
chr59600137696001517+intron-Distal5.8030010.00393HepG2HNRNPL
chr59610822096108300+intron-Distal,intron-Proximal3.954684.07352K562KHSRP
chr59606259396062667+intron-Distal,intron-Proximal4.100523.16986HepG2QKI
chr59600124096001293+intron-Distal3.737003.04956HepG2HNRNPL
chr59610055696100632+intron-Distal4.619353.37054HepG2XPO5
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for CAST is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for CAST is not available on ENCORE database.

  • 98 RBPs can affect the levels of CAST.  








The Knockdown/knockout RNA-Seq assay for CAST is not available on ENCORE database.





98 RBPs can affect the gene expression of CAST :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
CASTENSG00000153113.192299.155501666.149100.464505.164603.73950HepG2AATF
CASTENSG00000153113.194895.611402113.935301.2115080.0975078.00520HepG2ACO1
CASTENSG00000153113.191297.936701984.49580-0.612607.263905.74570HepG2ADAR
CASTENSG00000153113.195102.093002718.978400.9079013.0297011.96320HepG2AKAP1
CASTENSG00000153113.192903.847102249.707900.368102.955802.14490HepG2ASCC1
CASTENSG00000153113.191735.598703058.67920-0.8175027.1788025.42310HepG2AUH
CASTENSG00000153113.191537.559702612.16810-0.7646012.6914011.53340HepG2BOP1
CASTENSG00000153113.192792.775902183.096800.355203.509002.13260HepG2BUD13
CASTENSG00000153113.193439.628302663.164800.369004.781703.80170HepG2CALR
CASTENSG00000153113.191202.323202125.81170-0.822206.583505.40330HepG2CNOT7
CASTENSG00000153113.192955.038202399.549100.300302.774001.66860HepG2CPSF7
CASTENSG00000153113.194271.207902609.632400.7107021.6778020.22540HepG2CELF1
CASTENSG00000153113.192433.514502806.17590-0.205603.143702.36130HepG2DAZAP1
CASTENSG00000153113.192249.660201954.989400.202402.582301.77440HepG2DDX19B
CASTENSG00000153113.191783.947302604.53610-0.546005.539904.68270HepG2DDX3X
CASTENSG00000153113.193449.211702770.939000.315802.854701.54320HepG2DDX47
CASTENSG00000153113.193014.645101748.011300.786209.511708.17730HepG2DDX55
CASTENSG00000153113.194014.736902723.273400.559903.113302.07720HepG2DDX59
CASTENSG00000153113.194160.147202237.443400.8947012.5519011.34880HepG2DDX6
CASTENSG00000153113.191728.263202022.40810-0.226802.451401.80740HepG2DKC1
CASTENSG00000153113.191732.684301998.31180-0.205801.925301.32740HepG2DNAJC21
CASTENSG00000153113.191533.692601980.61880-0.368907.196506.21430HepG2DNAJC2
CASTENSG00000153113.192403.469901693.008100.505403.760502.45880HepG2AGO1
CASTENSG00000153113.192962.696802150.816300.461904.237303.51250HepG2EIF2S1
CASTENSG00000153113.192121.425801639.109100.372003.142702.18520HepG2EIF3D
CASTENSG00000153113.193649.913402768.309400.398807.737906.46950HepG2EIF4G1
CASTENSG00000153113.192153.397901752.348300.297202.525301.42870HepG2FASTKD2
CASTENSG00000153113.195288.020502942.543200.8456012.2627010.81020HepG2FIP1L1
CASTENSG00000153113.191706.818602224.69220-0.382302.784002.11670HepG2G3BP1
CASTENSG00000153113.192067.107102718.64160-0.395303.014502.34990HepG2GPKOW
CASTENSG00000153113.192392.169702018.073900.245203.101702.07150HepG2HDGF
CASTENSG00000153113.191350.897502017.45570-0.578607.971706.95870HepG2HNRNPA1
CASTENSG00000153113.193339.143202578.869000.372605.328704.10560HepG2HNRNPA2B1
CASTENSG00000153113.192381.237802880.48990-0.274604.106803.25070HepG2HNRNPF
CASTENSG00000153113.192188.126102556.26620-0.224303.548502.79230HepG2HNRNPL
CASTENSG00000153113.193317.398202594.437400.354503.091602.43050HepG2HNRNPLL
CASTENSG00000153113.191937.216302229.19570-0.202502.303601.74570HepG2HNRNPU
CASTENSG00000153113.192250.134702836.44870-0.334104.035103.17510HepG2IGF2BP1
CASTENSG00000153113.192901.999102261.325700.359802.912602.22350HepG2IGF2BP2
CASTENSG00000153113.192004.080502277.05230-0.184202.338901.65740HepG2ILF2
CASTENSG00000153113.191811.979802399.12540-0.404903.269602.55690HepG2MAGOH
CASTENSG00000153113.192513.452801715.521900.550903.427802.25870HepG2METAP2
CASTENSG00000153113.192559.821301999.570100.356303.423902.06990HepG2NAA15
CASTENSG00000153113.191066.522502469.34170-1.2112022.0465020.36800HepG2NCBP2
CASTENSG00000153113.191817.476202300.36520-0.339902.780202.02940HepG2NSUN2
CASTENSG00000153113.193160.544201942.980900.701804.598703.43480HepG2PABPC1
CASTENSG00000153113.191555.597402206.54170-0.5043010.221008.76720HepG2PARN
CASTENSG00000153113.191643.420602311.33230-0.492002.935601.68350HepG2PRPF6
CASTENSG00000153113.191841.820901348.431500.449803.836902.90480HepG2PRPF8
CASTENSG00000153113.193084.456402381.932100.372806.975206.18590HepG2PTBP1
CASTENSG00000153113.192021.656602819.58750-0.4799014.3127013.18530HepG2PUM1
CASTENSG00000153113.193431.595002817.564400.284303.048502.34390HepG2PUM2
CASTENSG00000153113.192421.365902153.149000.169301.883101.35450HepG2PUS1
CASTENSG00000153113.191654.904702579.78320-0.6405013.2512012.03160HepG2QKI
CASTENSG00000153113.194295.560402121.933601.017409.075807.84690HepG2RAVER1
CASTENSG00000153113.194800.940702953.869800.7006011.6235010.05040HepG2RBM15
CASTENSG00000153113.191354.220302341.28430-0.7898015.4474013.92350HepG2RBM25
CASTENSG00000153113.192338.792301333.876100.810009.958308.60210HepG2RRP9
CASTENSG00000153113.191563.469902568.05970-0.7159010.834409.52350HepG2SF3B1
CASTENSG00000153113.192276.971802546.73640-0.161502.026201.40830HepG2SLBP
CASTENSG00000153113.192999.424602315.102000.373509.478108.40260HepG2SMN1
CASTENSG00000153113.195309.048003315.160800.6793029.0115027.83500HepG2SRFBP1
CASTENSG00000153113.192908.276502588.526500.167901.808501.40270HepG2SRSF1
CASTENSG00000153113.191692.426202622.51470-0.6319017.1295015.76040HepG2SRSF5
CASTENSG00000153113.193032.257902105.877000.5259010.406309.45470HepG2SRSF9
CASTENSG00000153113.192045.139702878.40320-0.4931011.6858010.77470HepG2SSB
CASTENSG00000153113.193044.242401982.928600.618404.459602.92120HepG2SUB1
CASTENSG00000153113.192537.650701986.680500.353003.543502.48930HepG2SUPT6H
CASTENSG00000153113.192751.520001740.113100.660907.200706.19090HepG2SUPV3L1
CASTENSG00000153113.192747.632702326.581000.239902.528301.98950HepG2TAF15
CASTENSG00000153113.191330.248102528.40920-0.9265017.1414015.59840HepG2TARDBP
CASTENSG00000153113.191535.600201166.333700.396702.753201.76030HepG2TFIP11
CASTENSG00000153113.192676.628902137.903900.324103.484402.54980HepG2TIA1
CASTENSG00000153113.192473.227502185.439600.178401.903001.41790HepG2TRIM56
CASTENSG00000153113.194057.280802516.978100.688709.947508.74150HepG2U2AF1
CASTENSG00000153113.191364.490502024.18370-0.5690012.7135011.57080HepG2UTP3
CASTENSG00000153113.192843.541002086.165100.446702.568001.35930HepG2XRCC5
CASTENSG00000153113.191327.385201712.95070-0.367902.672701.96010HepG2XRN2
CASTENSG00000153113.191852.317302266.86870-0.291404.746503.90550HepG2ZC3H8
CASTENSG00000153113.193263.533202305.858400.5010016.3945015.34120HepG2ZNF622
CASTENSG00000153113.192297.386903825.47980-0.7356012.7123011.58640K562AQR
CASTENSG00000153113.194338.101403027.390800.518906.889504.93230K562CIRBP
CASTENSG00000153113.192906.955503406.74390-0.228902.052201.36770K562CPSF6
CASTENSG00000153113.192939.459601947.553900.593805.436703.60800K562EEF2
CASTENSG00000153113.192348.536903256.58230-0.471609.202508.00780K562EIF2S2
CASTENSG00000153113.193162.111702378.780200.410602.693401.99770K562G3BP2
CASTENSG00000153113.192746.568903252.53250-0.243901.982701.30700K562GPKOW
CASTENSG00000153113.192717.639904339.96590-0.675309.088807.69860K562GRSF1
CASTENSG00000153113.192994.278303941.71020-0.396604.877103.43130K562HNRNPL
CASTENSG00000153113.192249.348802968.59840-0.400304.585903.49580K562MAGOH
CASTENSG00000153113.191621.844503083.71060-0.9270038.1525035.76400K562MTPAP
CASTENSG00000153113.192027.605002583.21900-0.349404.182803.19590K562POLR2G
CASTENSG00000153113.191609.016502385.93770-0.568407.649506.00330K562PSIP1
CASTENSG00000153113.195475.818304146.823500.401003.941203.30940K562PUS1
CASTENSG00000153113.191976.836602766.08400-0.484705.180903.98970K562RBM22
CASTENSG00000153113.191301.669802256.64650-0.7938015.2814012.05370K562RBM25
CASTENSG00000153113.192778.912402177.072600.352004.042602.84270K562RCC2
CASTENSG00000153113.192310.302002910.72620-0.333302.720601.63680K562NELFE
CASTENSG00000153113.192719.676101872.460500.538404.210402.56550K562RRP9
CASTENSG00000153113.192963.874503380.84530-0.189902.007801.30560K562SF3A3
CASTENSG00000153113.191905.590502473.85600-0.376504.726703.59740K562SF3B4
CASTENSG00000153113.192203.850502827.26170-0.359402.652101.95900K562SRSF1
CASTENSG00000153113.192315.724002861.62830-0.305402.379001.72090K562TARDBP
CASTENSG00000153113.192307.078802760.29670-0.258802.357301.60890K562TIA1
CASTENSG00000153113.194398.717403587.678600.293904.911803.20970K562TROVE2
CASTENSG00000153113.192998.562202381.673100.332203.965303.00620K562U2AF2
CASTENSG00000153113.194048.147103232.594100.324503.089702.19720K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for CAST is not available on ENCORE database.





31 RBPs can affect the splicing of CAST :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SECASTENSG00000153113.19chr5+9606249796062563960583429605840296063192960632340.212000.000000.00001includedHepG2G3BP1
SECASTENSG00000153113.19chr5+960764489607648796075741960758229607696996077062-0.063000.003110.05128excludedK562SF3B4
SECASTENSG00000153113.19chr5+961062349610630696103610961037039610734796107406-0.236000.000000.00000excludedK562SF3B4
SECASTENSG00000153113.19chr5+960664839606656496065315960654299607187596071944-0.094000.000040.00132excludedK562SF3B4
SECASTENSG00000153113.19chr5+961062349610630696103610961037039610734796107406-0.121000.000010.00070excludedK562PRPF8
SECASTENSG00000153113.19chr5+961062349610630696103610961037039610734796107406-0.094000.000190.00507excludedHepG2U2AF1
SECASTENSG00000153113.19chr5+960820459608212996078358960784609608304896083096-0.070000.000020.00057excludedHepG2U2AF1
SECASTENSG00000153113.19chr5+960769699607706296075741960758229607719796077284-0.281000.000110.00318excludedHepG2U2AF1
SECASTENSG00000153113.19chr5+960648569606491396063192960632349606531596065429-0.245000.000000.00000excludedHepG2U2AF1
SECASTENSG00000153113.19chr5+960664839606656496065315960654299607187596071944-0.124000.000000.00000excludedHepG2U2AF1
SECASTENSG00000153113.19chr5+960764489607648796075741960758229607696996077062-0.055000.003930.08750excludedK562AKAP8L
SECASTENSG00000153113.19chr5+960648569606491396063192960632349606531596065429-0.118000.001070.03330excludedK562AKAP8L
SECASTENSG00000153113.19chr5+960781019607818296077197960772849607835896078460-0.105000.000250.03446excludedK562FMR1
SECASTENSG00000153113.19chr5+960631929606323496058342960584029606485696064913-0.073000.000070.01149excludedHepG2DDX59
SECASTENSG00000153113.19chr5+9606319296063234960583429605840296064856960649130.052000.000180.02028includedHepG2TBRG4
SECASTENSG00000153113.19chr5+960624979606256396058342960584029606319296063234-0.081000.000390.03816excludedHepG2QKI
SECASTENSG00000153113.19chr5+960820459608212996078358960784609608304896083096-0.125000.000000.00000excludedHepG2U2AF2
SECASTENSG00000153113.19chr5+960769699607706296075741960758229607719796077284-0.541000.000000.00000excludedHepG2U2AF2
SECASTENSG00000153113.19chr5+960648569606491396063192960632349606531596065429-0.328000.000000.00000excludedHepG2U2AF2
SECASTENSG00000153113.19chr5+960664839606656496065315960654299607187596071944-0.094000.000010.00016excludedHepG2U2AF2
SECASTENSG00000153113.19chr5+9606249796062563960583429605840296063192960632340.135000.000000.00041includedHepG2AKAP1
SECASTENSG00000153113.19chr5+9606485696064913960631929606323496065315960653950.150000.000270.01377includedK562FXR1
SECASTENSG00000153113.19chr5+961062349610630696103610961037039610734796107383-0.058000.002430.07718excludedK562FXR1
SECASTENSG00000153113.19chr5+960664839606656496065315960654299607187596071944-0.108000.000120.00727excludedK562FXR1
SECASTENSG00000153113.19chr5+9610623496106306961036109610370396107347961074060.054000.000570.09360includedK562HNRNPA1
SECASTENSG00000153113.19chr5+9606249796062563960583429605840296063192960632340.185000.000020.00830includedHepG2BCLAF1
SECASTENSG00000153113.19chr5+960764489607648796075741960758229607696996077062-0.053000.004140.05384excludedK562PUS1
SECASTENSG00000153113.19chr5+960648569606491396063192960632349606531596065429-0.170000.000000.00000excludedK562PUS1
SECASTENSG00000153113.19chr5+961062349610630696103610961037039610734796107406-0.074000.000030.00108excludedK562U2AF1
SECASTENSG00000153113.19chr5+960648569606491396063192960632349606531596065429-0.292000.000000.00000excludedK562U2AF1
SECASTENSG00000153113.19chr5+960664839606656496065315960654299607355296073651-0.124000.000000.00010excludedK562U2AF1
SECASTENSG00000153113.19chr5+9606249796062563960583429605840296063192960632340.207000.000000.00000includedHepG2HNRNPL
SECASTENSG00000153113.19chr5+9606648396066564960653159606542996071875960719440.069000.000180.01814includedK562HNRNPL
SECASTENSG00000153113.19chr5+960631929606323496058342960584029606485696064913-0.072000.000180.01790excludedK562HNRNPL
SECASTENSG00000153113.19chr5+9606245796062563960583429605840296063192960632340.080000.000700.02321includedHepG2SF3A3
SECASTENSG00000153113.19chr5+961062349610630696103610961037039610734796107406-0.100000.000000.00000excludedHepG2SF3A3
SECASTENSG00000153113.19chr5+960718759607194496065315960654299607355296073651-0.070000.004150.09176excludedHepG2SF3A3
SECASTENSG00000153113.19chr5+9606249796062563960583429605840296063192960632340.192000.000000.00000includedHepG2IGF2BP3
SECASTENSG00000153113.19chr5+9606249796062563960583429605840296063192960632340.177000.000150.01051includedHepG2PCBP1
SECASTENSG00000153113.19chr5+960648569606491396063192960632349606531596065429-0.114000.000060.00380excludedK562UTP18
SECASTENSG00000153113.19chr5+960820459608212996078339960784609608304896083096-0.116000.000000.00004excludedK562U2AF2
SECASTENSG00000153113.19chr5+960648569606491396063192960632349606531596065429-0.385000.000000.00000excludedK562U2AF2
SECASTENSG00000153113.19chr5+960664839606656496065315960654299607187596071944-0.100000.000000.00019excludedK562U2AF2
SECASTENSG00000153113.19chr5+9610623496106306961036109610370396107347961074060.064000.000000.00008includedK562HNRNPU
SECASTENSG00000153113.19chr5+960820459608212996078339960784609608304896083096-0.117000.000000.00000excludedK562HNRNPU
SECASTENSG00000153113.19chr5+960648569606491396063192960632349606531596065429-0.169000.000000.00001excludedK562RBM15
SECASTENSG00000153113.19chr5+960648569606491396063192960632349606531596065429-0.170000.000000.00001excludedK562AGGF1
SECASTENSG00000153113.19chr5+9610623496106306961036109610370396107347961074060.116000.000010.00274includedK562CPSF6
SECASTENSG00000153113.19chr5+960781019607818296077197960772849607835896078460-0.105000.000170.02553excludedK562CPSF6
SECASTENSG00000153113.19chr5+961062349610630696103610961037039610734796107406-0.192000.000240.01362excludedK562SF3B1
SECASTENSG00000153113.19chr5+960664839606656496065315960654299607355296073651-0.117000.000450.02166excludedK562SF3B1
SECASTENSG00000153113.19chr5+961062349610630696103610961037039610734796107399-0.063000.000610.03112excludedK562HNRNPK
SECASTENSG00000153113.19chr5+9606249796062563960583429605840296063192960632340.142000.000040.00346includedHepG2HNRNPU
SECASTENSG00000153113.19chr5+961062349610630696103610961037039610734796107406-0.097000.000000.00017excludedK562HNRNPC
SECASTENSG00000153113.19chr5+960664839606656496065315960654299607355296073651-0.075000.003370.05105excludedK562HNRNPC
A3SSCASTENSG00000153113.19chr5+9610090796101029961009279610102996097977960980760.089000.001730.01133longerK562AQR
MXECASTENSG00000153113.19chr5+96058342960584029606319296063234960315399603161196064856960649130.186000.000000.000081includedHepG2U2AF1
MXECASTENSG00000153113.19chr5+96063192960632349606485696064913960583429605840296065315960654290.206000.000010.000241includedHepG2U2AF1
MXECASTENSG00000153113.19chr5+9605834296058402960631929606323496031539960316119606531596065429-0.209000.000050.001752includedHepG2U2AF1
MXECASTENSG00000153113.19chr5+9608204596082129960830489608309696078358960784609608422196084317-0.104000.005200.074552includedHepG2U2AF1
MXECASTENSG00000153113.19chr5+96058342960584029606319296063234960315399603161196065315960654290.199000.000130.013881includedHepG2IGF2BP3
MXECASTENSG00000153113.19chr5+96065315960654299607187596071944960631929606323496073552960736510.121000.000010.000661includedK562RBM15
MXECASTENSG00000153113.19chr5+96063192960632349606485696064913960583429605840296065315960654290.173000.000050.001911includedK562U2AF1
MXECASTENSG00000153113.19chr5+96066483960665649607187596071944960653159606542996073552960736510.127000.001060.020671includedK562U2AF1
MXECASTENSG00000153113.19chr5+96065315960654299607187596071944960631929606323496073552960736510.095000.000110.003371includedK562PUS1
MXECASTENSG00000153113.19chr5+96063192960632349606485696064913960583429605840296065315960654290.096000.005510.074751includedK562PUS1
MXECASTENSG00000153113.19chr5+96065315960654299607187596071944960631929606323496073552960736510.104000.000060.004271includedK562AGGF1
MXECASTENSG00000153113.19chr5+96065315960654299607187596071944960631929606323496073552960736510.096000.000210.018861includedK562UTP18
MXECASTENSG00000153113.19chr5+96065315960654299607187596071944960583429605840296073552960736510.142000.000000.000001includedK562U2AF2
MXECASTENSG00000153113.19chr5+96063192960632349606485696064913960583429605840296065315960654290.218000.000000.000001includedK562U2AF2
MXECASTENSG00000153113.19chr5+96063192960632349606485696064913960583429605840296065315960654290.147000.002050.025801includedHepG2SFPQ
MXECASTENSG00000153113.19chr5+96065315960654299607187596071944960583429605840296073552960736510.074000.000000.000001includedHepG2U2AF2
MXECASTENSG00000153113.19chr5+96058342960584029606485696064913960315399603161196065315960654290.288000.000000.000001includedHepG2U2AF2
MXECASTENSG00000153113.19chr5+96058342960584029606319296063234960315399603161196064856960649130.123000.018350.086921includedHepG2U2AF2
MXECASTENSG00000153113.19chr5+96063192960632349606485696064913960314889603161196065315960654290.571000.000000.000001includedHepG2U2AF2
MXECASTENSG00000153113.19chr5+96063192960632349606485696064913960583429605840296065315960654290.280000.000000.000001includedHepG2U2AF2
MXECASTENSG00000153113.19chr5+9605834296058402960631929606323496031539960316119606531596065429-0.150000.006850.039582includedHepG2U2AF2
MXECASTENSG00000153113.19chr5+9606319296063234960648569606491396058342960584029606531596065429-0.176000.000910.032642includedHepG2PCBP1
MXECASTENSG00000153113.19chr5+96065315960654299607187596071944960583429605840296073552960736510.071000.000180.005211includedK562HNRNPC
MXECASTENSG00000153113.19chr5+96011242960113059603153996031611959979409599820196058342960584020.116000.000410.039611includedHepG2DDX59
MXECASTENSG00000153113.19chr5+96063192960632349606531596065429960583429605840296071875960719440.071000.000190.015651includedHepG2DDX6
MXECASTENSG00000153113.19chr5+96063192960632349606485696064913960583429605840296065315960654290.110000.001510.055041includedK562AKAP8L
MXECASTENSG00000153113.19chr5+96066483960665649607187596071944960653159606542996073552960736510.157000.000010.000551includedK562HNRNPUL1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for CAST is not avaliable on ENCORE database.