TMED5

General Information

Gene Name       : TMED5
Gene ID             : ENSG00000117500.12
Essential Gene : No

Functions

Localization

Domains (AlphaFold: TMED5)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878TMED5ENSG00000117500.1240.0932.2336.16ENCSR000AEF
HepG2TMED5ENSG00000117500.1251.2682.3766.81ENCSR985KAT
K562TMED5ENSG00000117500.1245.8640.9643.41ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for TMED5 is not avaliable on ENCORE database.



Proteins bound to RNA
  • TMED5 RNA is bound by 28 proteins.  







eCLIP assay for TMED5 is not avaliable on ENCORE database.





28 proteins are bound to TMED5 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr19361777193617804-3'-UTR,intron-Distal4.5490911.22333HepG2IGF2BP1
chr19361849193618555-3'-UTR,intron-Distal3.4972413.12458HepG2FAM120A
chr19361780493617820-3'-UTR,intron-Distal5.103368.53241HepG2IGF2BP1
chr19362188993621963-3'-UTR,CDS,intron-Distal4.1556212.80995HepG2BCLAF1
chr19362185593621889-3'-UTR,CDS,intron-Distal,intron-Proximal4.0762010.68403HepG2BCLAF1
chr19361876493618792-3'-UTR,intron-Distal3.591765.15749K562YBX3
chr19361936093619418-3'-UTR,intron-Distal3.359773.70826K562FAM120A
chr19361889093618911-3'-UTR,intron-Distal3.163614.26772K562FAM120A
chr19361741993617463-3'-UTR,intron-Distal4.917136.68732K562PUM2
chr19361908793619151-3'-UTR,intron-Distal3.655103.14501HepG2IGF2BP3
chr19362185493621905-3'-UTR,CDS,intron-Distal,intron-Proximal4.130745.59977HepG2AQR
chr19361833793618397-3'-UTR,intron-Distal3.659623.87559K562YBX3
chr19362185593621919-3'-UTR,CDS,intron-Distal,intron-Proximal3.978644.55748K562ZNF800
chr19361819693618248-3'-UTR,intron-Distal3.928493.73561HepG2IGF2BP3
chr19361841793618462-3'-UTR,intron-Distal4.060013.19668HepG2UPF1
chr19362185593621964-3'-UTR,CDS,intron-Distal,intron-Proximal3.088653.84518HepG2FXR2
chr19362189393621961-3'-UTR,CDS,intron-Distal4.006507.45151HepG2LIN28B
chr19361772793617771-3'-UTR,intron-Distal3.352764.47204HepG2IGF2BP1
chr19361849893618563-3'-UTR,intron-Distal3.066878.88207K562FAM120A
chr19361849493618551-3'-UTR,intron-Distal4.934846.83436HepG2IGF2BP1
chr19361848893618562-3'-UTR,intron-Distal3.015506.81933K562UPF1
chr19361788793617934-3'-UTR,intron-Distal4.124934.50986K562IGF2BP1
chr19362191693622010-3'-UTR,CDS,intron-Distal3.851885.08507K562ZNF622
chr19361936093619417-3'-UTR,intron-Distal3.288496.26731K562KHDRBS1
chr19361988893619949-3'-UTR,intron-Distal3.041645.23730K562FAM120A
chr19361772093617821-3'-UTR,intron-Distal3.150497.58767K562IGF2BP1
chr19362040393620448-3'-UTR,CDS,intron-Distal3.615608.84415HepG2BCLAF1
chr19361840493618476-3'-UTR,intron-Distal3.7015410.59083K562FAM120A
chr19361819493618238-3'-UTR,intron-Distal4.191804.47310HepG2IGF2BP1
chr19361879293618840-3'-UTR,intron-Distal4.2302910.21839K562YBX3
chr19361773493617821-3'-UTR,intron-Distal3.853007.86245HepG2IGF2BP3
chr19361819093618255-3'-UTR,intron-Distal3.122115.55412K562IGF2BP1
chr19364584093645898-5'-UTR,intron-Distal,intron-Proximal3.822806.18214HepG2GRWD1
chr19364584693645907-5'-UTR,intron-Distal,intron-Proximal4.6787117.01049K562DDX3X
chr19364569993645817-5'-UTR,CDS,intron-Distal3.011706.63950K562IGF2BP2
chr19364580293645838-5'-UTR,intron-Distal,intron-Proximal3.692363.19539K562YBX3
chr19364585093645896-5'-UTR,intron-Distal,intron-Proximal3.9647917.06640HepG2DDX3X
chr19364589893645950-5'-UTR,intron-Distal,intron-Proximal3.322804.25541HepG2GRWD1
chr19364589693645959-5'-UTR,intron-Distal,intron-Proximal4.6984059.78252HepG2DDX3X
chr19364570193645845-5'-UTR,CDS,intron-Distal,intron-Proximal3.7751118.04008HepG2RPS3
chr19364586093645930-5'-UTR,intron-Distal,intron-Proximal3.506993.34231K562RBM15
chr19364579093645827-5'-UTR,CDS,intron-Distal,intron-Proximal4.323977.41870HepG2DDX3X
chr19364562993645761-CDS,intron-Distal3.101255.81611K562GEMIN5
chr19364571493645785-CDS,intron-Distal3.753716.53690K562PCBP1
chr19364569793645778-CDS,intron-Distal4.0684951.03596HepG2DDX3X
chr19364571593645771-CDS,intron-Distal3.124244.10374K562DDX3X
chr19364564193645685-CDS,intron-Distal3.2773017.22246HepG2DDX3X
chr19364562093645662-CDS,intron-Distal3.4696412.42588K562YBX3
chr19364566293645699-CDS,intron-Distal3.524549.95573K562YBX3
chr19362568593625775-CDS,intron-Distal,intron-Proximal3.342126.19339HepG2BCLAF1
chr19362570693625773-CDS,intron-Distal3.134043.07714K562YBX3
chr19364571293645784-CDS,intron-Distal4.845058.39672HepG2PCBP1
chr19363539593635506-intron-Distal4.978784.67055K562EIF4G2
chr19363372693633777-intron-Distal4.450823.18981K562PTBP1
chr19363503993635138-intron-Distal4.431023.01445K562EXOSC5
chr19363811693638226-intron-Distal3.550755.84619HepG2QKI
chr19363812593638185-intron-Distal4.922065.76685K562EXOSC5
chr19363540793635461-intron-Distal4.507025.12432K562EXOSC5
chr19363811393638176-intron-Distal3.724053.04224HepG2SUGP2
chr19363718393637222-intron-Distal4.249733.59909K562EXOSC5
chr19363540393635462-intron-Distal4.717285.97091K562TARDBP
chr19363712593637265-intron-Distal4.567375.72853HepG2HNRNPM
chr19363094693631217-intron-Distal3.491596.14017HepG2HNRNPL
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for TMED5 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for TMED5 is not available on ENCORE database.

  • 111 RBPs can affect the levels of TMED5.  








The Knockdown/knockout RNA-Seq assay for TMED5 is not available on ENCORE database.





111 RBPs can affect the gene expression of TMED5 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
TMED5ENSG00000117500.83576.688604933.97560-0.464104.680203.67200HepG2ASCC1
TMED5ENSG00000117500.85280.093304543.803400.216602.900902.20000HepG2AUH
TMED5ENSG00000117500.82287.859903314.09570-0.534603.391902.35530HepG2BCCIP
TMED5ENSG00000117500.83778.478002880.025000.391603.852402.80860HepG2BCLAF1
TMED5ENSG00000117500.85690.191704349.819600.387404.476303.73620HepG2BOP1
TMED5ENSG00000117500.86359.634403700.410600.7812014.8645013.32650HepG2CALR
TMED5ENSG00000117500.85681.618104687.582000.277402.139001.45370HepG2CIRBP
TMED5ENSG00000117500.85683.013803993.474900.508906.680405.64750HepG2CPSF6
TMED5ENSG00000117500.84023.147402457.048300.7113014.8081012.80840HepG2DDX24
TMED5ENSG00000117500.81979.041303258.26990-0.719305.876004.80030HepG2DDX55
TMED5ENSG00000117500.85196.587803896.815500.415204.332803.07790HepG2DDX5
TMED5ENSG00000117500.81676.294402885.58670-0.7836022.2219020.44120HepG2DNAJC21
TMED5ENSG00000117500.81269.703602859.88230-1.1715056.5244053.88140HepG2DNAJC2
TMED5ENSG00000117500.84066.356802804.972400.535706.623505.25830HepG2EEF2
TMED5ENSG00000117500.83218.452002338.583700.460604.887503.41640HepG2EFTUD2
TMED5ENSG00000117500.83101.339802312.264400.423502.381301.35820HepG2AGO1
TMED5ENSG00000117500.83155.657302277.145200.470604.759103.59700HepG2EIF3D
TMED5ENSG00000117500.83172.958602371.542000.419904.120902.83050HepG2EIF3G
TMED5ENSG00000117500.86574.842805213.356400.334602.360101.76800HepG2EIF4A3
TMED5ENSG00000117500.85667.055404134.400600.454802.350501.59760HepG2EIF4G2
TMED5ENSG00000117500.84389.110203474.549600.337003.444502.23130HepG2ESF1
TMED5ENSG00000117500.86632.789205216.923200.346307.743406.82370HepG2ETF1
TMED5ENSG00000117500.82771.286005259.27450-0.9243016.4950014.95380HepG2FXR1
TMED5ENSG00000117500.83304.593804879.16050-0.562205.895404.94010HepG2G3BP1
TMED5ENSG00000117500.86683.481504527.198600.561904.675103.85700HepG2GPKOW
TMED5ENSG00000117500.84812.211503381.598900.508902.716601.36410HepG2HLTF
TMED5ENSG00000117500.83099.165803684.93390-0.249803.316402.53720HepG2HNRNPF
TMED5ENSG00000117500.83250.215603985.69610-0.294304.380803.54680HepG2HNRNPL
TMED5ENSG00000117500.86736.602604320.363300.640808.410207.37690HepG2HNRNPLL
TMED5ENSG00000117500.82241.639003218.93650-0.5220013.4799012.22170HepG2HNRNPU
TMED5ENSG00000117500.86977.663804959.706700.492405.490004.56880HepG2IGF2BP2
TMED5ENSG00000117500.82407.489202986.59920-0.311004.864703.51910HepG2KIF1C
TMED5ENSG00000117500.84124.673405261.10710-0.351102.824602.16320HepG2MAGOH
TMED5ENSG00000117500.84259.619405415.40910-0.346302.631402.01260HepG2NCBP2
TMED5ENSG00000117500.84571.390303830.622400.255002.032101.38650HepG2NSUN2
TMED5ENSG00000117500.84228.095702783.442300.603003.587302.56710HepG2PABPC1
TMED5ENSG00000117500.83529.796204823.25100-0.450404.257703.37370HepG2PABPC4
TMED5ENSG00000117500.82365.214703186.28900-0.429908.922607.54340HepG2PARN
TMED5ENSG00000117500.83862.666004426.90070-0.196702.720102.11740HepG2PCBP1
TMED5ENSG00000117500.81442.909303341.20750-1.2114015.2330013.09930HepG2PCBP2
TMED5ENSG00000117500.8821.856102468.00300-1.5864081.6959078.81990HepG2PRPF4
TMED5ENSG00000117500.83693.055402514.438800.554507.116705.89170HepG2PRPF8
TMED5ENSG00000117500.82994.920404504.42520-0.5888017.7042016.54950HepG2PTBP1
TMED5ENSG00000117500.85382.414204141.214900.378104.248903.52860HepG2PUF60
TMED5ENSG00000117500.81630.765404395.86150-1.4306052.7839050.87500HepG2PUM1
TMED5ENSG00000117500.86042.225804392.787900.459807.612306.52400HepG2PUM2
TMED5ENSG00000117500.82437.427303327.62010-0.449108.994507.98900HepG2PUS1
TMED5ENSG00000117500.82708.536204360.37640-0.6869019.6529018.53170HepG2RBM22
TMED5ENSG00000117500.88128.140004427.591200.8763016.9419015.36290HepG2RBM25
TMED5ENSG00000117500.81610.565304072.37780-1.338303.478601.62950HepG2RBM39
TMED5ENSG00000117500.84335.848505013.08570-0.209403.013702.45390HepG2NELFE
TMED5ENSG00000117500.81810.374902215.64170-0.291402.511801.92340HepG2RPS19
TMED5ENSG00000117500.83466.426702487.393400.478704.893503.88110HepG2RRP9
TMED5ENSG00000117500.83793.720502866.649100.404105.628404.76250HepG2SAFB2
TMED5ENSG00000117500.88007.320104548.412600.815909.008007.73730HepG2SF3A3
TMED5ENSG00000117500.82670.878803343.07100-0.323903.519002.80800HepG2SMN1
TMED5ENSG00000117500.86408.478504758.264000.429402.580901.82680HepG2SNRNP70
TMED5ENSG00000117500.84044.662904924.87410-0.284105.564804.92240HepG2SRFBP1
TMED5ENSG00000117500.87594.131104895.146400.6334020.2628019.23050HepG2SRSF1
TMED5ENSG00000117500.84725.656303013.407500.649005.278003.61900HepG2SUB1
TMED5ENSG00000117500.83880.345202735.204900.504408.300006.73340HepG2SUPT6H
TMED5ENSG00000117500.85582.671904399.721400.343405.555604.80890HepG2TAF15
TMED5ENSG00000117500.82499.552204210.26450-0.752209.898708.65220HepG2TARDBP
TMED5ENSG00000117500.82699.129702174.394300.311802.481801.53170HepG2TFIP11
TMED5ENSG00000117500.82736.817703128.07680-0.192801.721301.30690HepG2TIAL1
TMED5ENSG00000117500.82592.146603155.74060-0.283804.604103.91420HepG2TRIM56
TMED5ENSG00000117500.83506.236304281.78740-0.288302.161401.42690HepG2UBE2L3
TMED5ENSG00000117500.84744.823004033.740500.234103.944303.13340HepG2UPF1
TMED5ENSG00000117500.84899.010504146.166800.240603.342202.20460HepG2UTP18
TMED5ENSG00000117500.82069.835903193.18860-0.625504.691203.75560HepG2XRN2
TMED5ENSG00000117500.83334.409602435.595500.4531012.5747011.31330HepG2ZC3H8
TMED5ENSG00000117500.85637.493404436.351000.3456010.343009.45500HepG2ZNF622
TMED5ENSG00000117500.85116.045203221.178100.667306.119604.09790HepG2ZRANB2
TMED5ENSG00000117500.83579.297204516.23150-0.335403.070501.77190K562ABCF1
TMED5ENSG00000117500.82798.222003259.36930-0.220103.012002.42320K562AGGF1
TMED5ENSG00000117500.81898.690102220.78040-0.226102.809201.84190K562BCLAF1
TMED5ENSG00000117500.8819.047501084.87860-0.405503.136401.99730K562CCAR1
TMED5ENSG00000117500.83220.302504115.72690-0.354004.057202.69980K562CPEB4
TMED5ENSG00000117500.81917.702702750.61570-0.520407.906806.56640K562CPSF6
TMED5ENSG00000117500.81191.077601684.79300-0.500307.459205.60090K562CSTF2
TMED5ENSG00000117500.81901.115102421.02390-0.348805.053203.37780K562DDX21
TMED5ENSG00000117500.84389.191003649.768700.266103.388802.40610K562DKC1
TMED5ENSG00000117500.81836.449002297.96800-0.323404.719603.11810K562EIF2S1
TMED5ENSG00000117500.83910.903004968.22350-0.345204.207603.05710K562EIF4G2
TMED5ENSG00000117500.81535.622601899.80120-0.307002.793901.52260K562EXOSC5
TMED5ENSG00000117500.82257.683203246.61840-0.524106.656405.29690K562FIP1L1
TMED5ENSG00000117500.82287.796202798.66560-0.290802.184801.42210K562FMR1
TMED5ENSG00000117500.81758.441702372.11250-0.431903.930902.82500K562FTO
TMED5ENSG00000117500.83541.643202306.391300.618705.515704.43970K562G3BP2
TMED5ENSG00000117500.81736.867002626.16960-0.596508.732207.31420K562GPKOW
TMED5ENSG00000117500.82752.093404103.25140-0.576204.055003.14250K562GRSF1
TMED5ENSG00000117500.82069.540602577.51680-0.316703.237202.07390K562HNRNPA1
TMED5ENSG00000117500.81488.600902154.22510-0.533205.219004.42260K562HNRNPC
TMED5ENSG00000117500.81320.517901923.40380-0.542605.704603.98280K562HNRNPF
TMED5ENSG00000117500.83072.519103848.83830-0.325003.473902.27160K562HNRNPL
TMED5ENSG00000117500.82252.192802854.22670-0.341804.692003.52100K562HNRNPU
TMED5ENSG00000117500.8824.466301133.42790-0.459203.582301.87560K562ILF3
TMED5ENSG00000117500.81604.847202242.39900-0.482603.374302.33180K562KRR1
TMED5ENSG00000117500.81605.779902184.19020-0.443803.935902.12540K562LIN28B
TMED5ENSG00000117500.81797.829002563.43100-0.511806.870305.45680K562METAP2
TMED5ENSG00000117500.81854.207602991.89930-0.6903022.2397020.26390K562MTPAP
TMED5ENSG00000117500.82447.758503324.29910-0.4416014.5847013.05920K562NSUN2
TMED5ENSG00000117500.81647.140302120.54580-0.364502.881301.41750K562NUSAP1
TMED5ENSG00000117500.81806.639702767.84730-0.615502.902701.88170K562PABPN1
TMED5ENSG00000117500.82373.188402870.66410-0.274602.670101.34720K562PCBP1
TMED5ENSG00000117500.81489.608402613.34940-0.8110014.8826012.48600K562PCBP2
TMED5ENSG00000117500.81773.626102416.53940-0.446203.975802.97830K562PCBP3
TMED5ENSG00000117500.81604.336402102.94500-0.390402.807801.37230K562PHF6
TMED5ENSG00000117500.81484.486501853.56710-0.320303.115302.26280K562POLR2G
TMED5ENSG00000117500.82738.249503685.70870-0.428704.501503.41960K562PPIG
TMED5ENSG00000117500.82304.795801739.563000.405803.122802.32500K562PRPF8
TMED5ENSG00000117500.81342.902101931.39900-0.524304.611403.40010K562PSIP1
TMED5ENSG00000117500.84158.915005764.96300-0.471105.094603.61370K562PUM1
TMED5ENSG00000117500.82058.925702736.47070-0.410404.256903.18660K562RBM22
TMED5ENSG00000117500.82297.689202879.62060-0.325702.600601.54440K562NELFE
TMED5ENSG00000117500.81797.172102343.59020-0.383003.721501.72680K562RECQL
TMED5ENSG00000117500.82785.748703280.18970-0.235702.941502.10350K562SF3A3
TMED5ENSG00000117500.81974.490102399.55610-0.281302.774801.91820K562SF3B4
TMED5ENSG00000117500.82388.312803437.88860-0.525503.453601.48350K562SMN1
TMED5ENSG00000117500.81334.732601670.10790-0.323402.557301.58250K562SRFBP1
TMED5ENSG00000117500.82622.024403360.62110-0.358008.115106.61060K562SRPK2
TMED5ENSG00000117500.81763.438602160.57470-0.293003.722002.35650K562SRSF7
TMED5ENSG00000117500.81080.608201684.93260-0.640802.966501.91210K562SUPV3L1
TMED5ENSG00000117500.82389.026001859.177500.361704.304603.27360K562SYNCRIP
TMED5ENSG00000117500.82151.765002831.18420-0.395903.669702.85060K562TARDBP
TMED5ENSG00000117500.82109.767402730.95850-0.372304.485903.40680K562TIA1
TMED5ENSG00000117500.81125.866901857.73510-0.722507.776506.13860K562TIAL1
TMED5ENSG00000117500.82070.427902679.53680-0.372103.809902.49400K562TRA2A
TMED5ENSG00000117500.81431.397401973.12170-0.463104.439103.17760K562TRIM56
TMED5ENSG00000117500.82786.385603797.29380-0.446604.573402.66340K562TRIP6
TMED5ENSG00000117500.82831.846803524.82240-0.315805.977904.96770K562UPF1
TMED5ENSG00000117500.81985.833303016.08310-0.6029010.194508.47700K562WDR3
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for TMED5 is not available on ENCORE database.





4 RBPs can affect the splicing of TMED5 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SETMED5ENSG00000117500.8chr1-9362159293621641936197889362044593621856936219310.056000.000000.00000includedHepG2U2AF1
SETMED5ENSG00000117500.8chr1-9362159293621641936197889362044593621856936220400.063000.000000.00000includedHepG2SRSF1
SETMED5ENSG00000117500.8chr1-9362437193624442936218569362204093625685936257830.055000.002610.05748includedK562AGGF1
A3SSTMED5ENSG00000117500.8chr1-9362568593625877936256859362578393645610936460730.096000.000000.00000longerK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for TMED5 is not avaliable on ENCORE database.