SPOPL

General Information

Gene Name       : SPOPL
Gene ID             : ENSG00000144228.8
Essential Gene : No

Functions

Localization

Domains (AlphaFold: SPOPL)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878SPOPLENSG00000144228.813.8011.1212.46ENCSR000AEF
HepG2SPOPLENSG00000144228.811.5123.5117.51ENCSR985KAT
K562SPOPLENSG00000144228.82.181.842.01ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for SPOPL is not avaliable on ENCORE database.



Proteins bound to RNA
  • SPOPL RNA is bound by 21 proteins.  







eCLIP assay for SPOPL is not avaliable on ENCORE database.





21 proteins are bound to SPOPL RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr2139322509139322565+3'-UTR,CDS,intron-Proximal3.658409.83905HepG2BCLAF1
chr2139326556139326667+3'-UTR,CDS3.433504.45064HepG2GRWD1
chr2139318470139318500+3'-UTR,CDS,intron-Proximal3.796396.81385HepG2BCLAF1
chr2139329130139329167+3'-UTR,intron-Distal3.290303.12167HepG2FUBP3
chr2139322275139322315+3'-UTR,CDS,intron-Proximal3.215075.91405HepG2BCLAF1
chr2139326675139326739+3'-UTR3.169114.26492HepG2BCLAF1
chr2139322315139322395+3'-UTR,CDS3.911826.39464HepG2BCLAF1
chr2139326557139326605+3'-UTR,CDS3.930564.51739HepG2BCLAF1
chr2139328662139328745+3'-UTR,intron-Distal3.382624.51074HepG2HNRNPL
chr2139308581139308633+3'-UTR,CDS,intron-Proximal3.033783.11350HepG2BCLAF1
chr2139330807139330892+3'-UTR,intron-Distal3.776043.11181HepG2CSTF2
chr2139329546139329629+3'-UTR,intron-Distal6.0081316.76921K562TARDBP
chr2139318373139318470+3'-UTR,CDS,intron-Proximal4.1595513.12590HepG2BCLAF1
chr2139329629139329703+3'-UTR,intron-Distal5.4738110.75912K562TARDBP
chr2139318408139318487+3'-UTR,CDS4.205794.10264K562ZNF622
chr2139330490139330547+3'-UTR,intron-Distal3.669804.13343HepG2FUBP3
chr2139308535139308581+3'-UTR,CDS,intron-Proximal3.657635.56491HepG2BCLAF1
chr2139259503139259624+5'-UTR4.1712823.77987HepG2NCBP2
chr2139316723139316746+5'-UTR,CDS4.554104.78529HepG2BCLAF1
chr2139259477139259575+5'-UTR4.634114.46189K562GTF2F1
chr2139259423139259481+5'-UTR3.775797.36734HepG2DDX3X
chr2139259480139259623+5'-UTR6.3620077.08256HepG2PRPF4
chr2139259431139259480+5'-UTR5.037379.47372HepG2PRPF4
chr2139259498139259594+5'-UTR3.2303219.26441HepG2DDX3X
chr2139316746139316770+5'-UTR,CDS,intron-Proximal4.190616.65960HepG2BCLAF1
chr2139316742139316808+5'-UTR,CDS,intron-Proximal5.025964.35676HepG2PRPF8
chr2139316587139316624+5'-UTR,CDS,intron-Proximal3.198864.61799HepG2BCLAF1
chr2139259656139259731+5'-UTR,intron-Proximal3.8251714.10710HepG2PRPF8
chr2139259429139259483+5'-UTR3.251845.09109HepG2GTF2F1
chr2139259505139259602+5'-UTR5.8659211.19348K562NCBP2
chr2139259500139259632+5'-UTR4.6014721.93610HepG2GTF2F1
chr2139316851139316910+5'-UTR,CDS,intron-Proximal4.125429.69111HepG2BCLAF1
chr2139316569139316628+5'-UTR,CDS,intron-Proximal3.106695.40388HepG2U2AF2
chr2139308449139308518+CDS,intron-Proximal3.6537910.79618HepG2U2AF2
chr2139266258139266312+intron-Distal3.023963.07694HepG2HNRNPC
chr2139285338139285427+intron-Distal3.414774.08528HepG2SUGP2
chr2139294232139294323+intron-Distal3.622294.08528HepG2SUGP2
chr2139259907139260039+intron-Distal4.078063.34627K562HNRNPK
chr2139324975139325054+intron-Distal5.377968.52451K562EIF4G2
chr2139261554139261654+intron-Distal3.805263.66668K562KHSRP
chr2139308280139308349+intron-Distal4.572935.87902HepG2KHSRP
chr2139307414139307508+intron-Distal3.940583.02234K562KHSRP
chr2139312667139312772+intron-Distal3.832865.17677K562EIF4G2
chr2139260462139260608+intron-Distal5.000485.72657HepG2MATR3
chr2139261772139261836+intron-Distal3.992574.48405HepG2CSTF2
chr2139260078139260128+intron-Distal4.061858.17775HepG2RBFOX2
chr2139308240139308370+intron-Distal,intron-Proximal3.197215.43929K562KHSRP
chr2139295924139295979+intron-Distal4.122294.36036HepG2SUGP2
chr2139313722139313804+intron-Distal3.065883.51696K562KHSRP
chr2139268814139268865+intron-Distal4.346094.20763HepG2U2AF2
chr2139294384139294440+intron-Distal3.045983.10883HepG2SUGP2
chr2139278392139278479+intron-Distal3.881263.92684K562KHSRP
chr2139295160139295258+intron-Distal3.392573.69184HepG2SUGP2
chr2139285943139286060+intron-Distal3.940583.02234K562KHSRP
chr2139301016139301134+intron-Distal3.513123.10961HepG2MATR3
chr2139260077139260145+intron-Distal4.169223.53160K562RBFOX2
chr2139292326139292373+intron-Distal3.352543.06005HepG2QKI
chr2139259704139259767+intron-Proximal4.005613.41442HepG2HNRNPK
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for SPOPL is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for SPOPL is not available on ENCORE database.

  • 108 RBPs can affect the levels of SPOPL.  








The Knockdown/knockout RNA-Seq assay for SPOPL is not available on ENCORE database.





108 RBPs can affect the gene expression of SPOPL :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
SPOPLENSG00000144228.4554.304901358.80260-1.2936024.4797022.09900HepG2ADAR
SPOPLENSG00000144228.41611.513002310.55740-0.519804.288503.64690HepG2AKAP1
SPOPLENSG00000144228.4952.588901399.55280-0.555009.804208.46740HepG2AKAP8L
SPOPLENSG00000144228.42687.857101940.555900.469905.219704.32620HepG2AUH
SPOPLENSG00000144228.4631.407401385.93320-1.1342011.495809.53080HepG2BCCIP
SPOPLENSG00000144228.41391.899501031.934200.431604.347102.82080HepG2BUD13
SPOPLENSG00000144228.41469.816802151.15930-0.549502.487401.57010HepG2CCAR1
SPOPLENSG00000144228.42785.714701816.339800.616907.509606.28400HepG2CIRBP
SPOPLENSG00000144228.4828.682201392.72350-0.7490016.1960014.87120HepG2CKAP4
SPOPLENSG00000144228.41994.168401348.108600.564806.664405.63280HepG2CPSF6
SPOPLENSG00000144228.41082.73240856.282400.338402.743801.67120HepG2CSTF2
SPOPLENSG00000144228.41105.761901288.30070-0.220402.312701.54550HepG2DDX19B
SPOPLENSG00000144228.4927.560101254.21570-0.435304.001803.20000HepG2DDX21
SPOPLENSG00000144228.41617.811401227.516400.398204.175003.04230HepG2DDX24
SPOPLENSG00000144228.41372.168402213.35810-0.689808.101307.08030HepG2DDX3X
SPOPLENSG00000144228.42049.475501641.174200.320402.605001.34440HepG2DDX47
SPOPLENSG00000144228.4554.685401010.64750-0.8655013.0432010.53030HepG2DDX52
SPOPLENSG00000144228.4801.402201362.58700-0.765706.760705.61550HepG2DDX55
SPOPLENSG00000144228.42117.419101332.675100.667904.161103.36420HepG2DKC1
SPOPLENSG00000144228.4813.094401368.28750-0.7509013.5233012.06090HepG2DNAJC21
SPOPLENSG00000144228.4559.328101356.11560-1.2777049.4237046.92400HepG2DNAJC2
SPOPLENSG00000144228.4816.693101205.89190-0.562204.974603.77180HepG2EEF2
SPOPLENSG00000144228.4658.79570978.95270-0.571404.359403.24420HepG2EIF3D
SPOPLENSG00000144228.41192.462101966.65490-0.721806.144005.14870HepG2EIF4B
SPOPLENSG00000144228.42656.151402227.858500.253602.966702.34750HepG2ETF1
SPOPLENSG00000144228.4809.032801122.19910-0.472103.767501.76590HepG2EXOSC9
SPOPLENSG00000144228.4638.33150874.86690-0.454804.308602.82310HepG2FAM120A
SPOPLENSG00000144228.4755.861301390.68870-0.879609.851808.51870HepG2FIP1L1
SPOPLENSG00000144228.41480.270601134.239400.384003.239801.87020HepG2FKBP4
SPOPLENSG00000144228.41253.568002037.97070-0.701108.456207.30180HepG2FXR1
SPOPLENSG00000144228.41434.388501890.55080-0.398402.885102.20570HepG2G3BP1
SPOPLENSG00000144228.41443.469202007.01740-0.475504.405503.27080HepG2G3BP2
SPOPLENSG00000144228.4807.881601528.27310-0.9197011.5758010.34180HepG2GPKOW
SPOPLENSG00000144228.41129.586001956.02030-0.792106.857705.11340HepG2GRSF1
SPOPLENSG00000144228.41690.416501329.904600.346003.944902.79300HepG2HDGF
SPOPLENSG00000144228.41236.229101830.36340-0.5662011.630309.95710HepG2HNRNPA2B1
SPOPLENSG00000144228.41575.520401914.27420-0.281001.980301.38230HepG2HNRNPK
SPOPLENSG00000144228.41166.006801814.39590-0.6379018.3064016.71610HepG2HNRNPL
SPOPLENSG00000144228.4529.04350959.57650-0.8590012.1699010.42150HepG2HNRNPM
SPOPLENSG00000144228.4859.759101526.36060-0.8281021.8495020.25860HepG2HNRNPU
SPOPLENSG00000144228.4943.680401400.78990-0.569903.703202.27860HepG2HSPD1
SPOPLENSG00000144228.4761.894001062.77360-0.480204.959504.01580HepG2IGF2BP1
SPOPLENSG00000144228.41187.889001559.13190-0.392307.003205.89200HepG2ILF2
SPOPLENSG00000144228.41233.417302013.34420-0.706906.815804.84540HepG2KHDRBS1
SPOPLENSG00000144228.42523.939402050.102700.299901.839901.32000HepG2MATR3
SPOPLENSG00000144228.4586.699601024.58880-0.804405.171303.76150HepG2METAP2
SPOPLENSG00000144228.4692.315301125.62940-0.701208.972207.59590HepG2MSI2
SPOPLENSG00000144228.41289.248801974.99900-0.615307.843906.57790HepG2NOL12
SPOPLENSG00000144228.4793.398201293.13290-0.704806.486705.36540HepG2NSUN2
SPOPLENSG00000144228.4446.19110731.89050-0.714004.151202.20120HepG2PA2G4
SPOPLENSG00000144228.41277.954601868.80380-0.548305.245804.26200HepG2PABPC4
SPOPLENSG00000144228.4979.585701510.87280-0.6251012.5147010.92370HepG2PARN
SPOPLENSG00000144228.41116.592301868.97270-0.7431019.2490017.88090HepG2PCBP1
SPOPLENSG00000144228.4631.46670809.56280-0.358402.811301.57220HepG2PKM
SPOPLENSG00000144228.4993.814901361.39690-0.454006.115905.05230HepG2PPIL4
SPOPLENSG00000144228.4453.14180812.83070-0.8430014.2056012.66370HepG2PRPF4
SPOPLENSG00000144228.42541.980901885.247300.431104.812204.05220HepG2PUF60
SPOPLENSG00000144228.41507.426202001.20040-0.408808.629807.70530HepG2PUM1
SPOPLENSG00000144228.41521.232401999.78390-0.394605.027604.13770HepG2PUM2
SPOPLENSG00000144228.42022.576901501.153000.430001.974601.36950HepG2RAVER1
SPOPLENSG00000144228.41200.294501862.11070-0.633608.199607.41740HepG2RBM22
SPOPLENSG00000144228.42943.969202116.474800.4760010.313209.39040HepG2NELFE
SPOPLENSG00000144228.4577.78940952.53150-0.721208.967307.93580HepG2RPS19
SPOPLENSG00000144228.41508.241502121.72800-0.492403.344202.46590HepG2RPS3A
SPOPLENSG00000144228.4983.748901359.30910-0.466507.990506.98130HepG2SAFB2
SPOPLENSG00000144228.4522.47280956.06540-0.8718010.457408.68070HepG2SERBP1
SPOPLENSG00000144228.44117.886601466.118301.4898025.4301023.32740HepG2SF3A3
SPOPLENSG00000144228.42022.451601443.628900.486304.032303.19590HepG2SF3B1
SPOPLENSG00000144228.41533.704101807.50870-0.237003.275602.52290HepG2SLBP
SPOPLENSG00000144228.4812.936601585.21370-0.9635028.8504027.13570HepG2SMN1
SPOPLENSG00000144228.43297.702702103.244200.6487018.0363017.05360HepG2SRFBP1
SPOPLENSG00000144228.43566.965202066.654800.7873022.5995021.52880HepG2SRSF1
SPOPLENSG00000144228.42082.770001553.206900.423202.843001.82670HepG2SRSF3
SPOPLENSG00000144228.41603.610501861.31980-0.215002.468701.87280HepG2SRSF5
SPOPLENSG00000144228.42046.126201681.356300.283204.081203.43570HepG2SRSF9
SPOPLENSG00000144228.43744.702201826.216501.0359052.3027050.75940HepG2SSB
SPOPLENSG00000144228.4530.93280928.97640-0.807106.741204.92410HepG2STAU1
SPOPLENSG00000144228.41982.286601402.808900.498703.040801.77650HepG2SUB1
SPOPLENSG00000144228.41714.887002116.90810-0.303805.235104.42670HepG2SUCLG1
SPOPLENSG00000144228.4851.264601412.88520-0.731004.327602.65480HepG2SUGP2
SPOPLENSG00000144228.41799.077701356.549500.407203.410902.66950HepG2SUPV3L1
SPOPLENSG00000144228.42229.241301857.662700.263002.822902.25710HepG2TAF15
SPOPLENSG00000144228.41085.860801421.30780-0.388403.166302.39550HepG2TARDBP
SPOPLENSG00000144228.4705.699601483.25590-1.0716025.5061024.27560HepG2TIAL1
SPOPLENSG00000144228.41007.182301496.39560-0.5712011.1143010.09570HepG2TRIM56
SPOPLENSG00000144228.4596.04220801.43430-0.427202.509001.78670HepG2UCHL5
SPOPLENSG00000144228.4719.919401336.46620-0.8925020.8501018.43790HepG2UTP18
SPOPLENSG00000144228.41566.71630802.135700.9657032.0568030.24910HepG2ZC3H8
SPOPLENSG00000144228.42022.129301499.423100.431402.669901.40020HepG2ZRANB2
SPOPLENSG00000144228.4700.04350294.953601.2469024.8955023.30420K562AGGF1
SPOPLENSG00000144228.4646.69270306.921801.0751014.6125012.91860K562AKAP8L
SPOPLENSG00000144228.4695.15550364.042800.9331010.479909.44770K562AQR
SPOPLENSG00000144228.4276.69680182.278600.602102.883601.43280K562BUD13
SPOPLENSG00000144228.4739.25720512.796900.527605.154003.81500K562CELF1
SPOPLENSG00000144228.4196.75940310.34490-0.657402.463801.88580K562FXR1
SPOPLENSG00000144228.4583.00840240.332101.278407.149804.86410K562HNRNPA2B1
SPOPLENSG00000144228.4695.57530325.688401.094609.672907.87340K562KIF1C
SPOPLENSG00000144228.4258.96910367.30640-0.504203.175302.18220K562MATR3
SPOPLENSG00000144228.4588.94410255.741701.203302.807901.91710K562NAA15
SPOPLENSG00000144228.4382.25820210.108700.863303.183702.10180K562PABPN1
SPOPLENSG00000144228.4468.76920327.479800.517402.910901.90880K562PCBP2
SPOPLENSG00000144228.4595.75520455.120600.388402.467601.69900K562PUF60
SPOPLENSG00000144228.41089.16010304.316401.8395040.5192038.38360K562PUS1
SPOPLENSG00000144228.4667.04050296.565001.1693019.9037018.27470K562RBM15
SPOPLENSG00000144228.4426.23120310.891400.455102.647801.34970K562RBM25
SPOPLENSG00000144228.4633.03240258.476001.292103.307001.59410K562RBM39
SPOPLENSG00000144228.494.84370149.88180-0.660202.194001.31430K562RCC2
SPOPLENSG00000144228.4254.54780360.84700-0.503502.788901.69140K562NELFE
SPOPLENSG00000144228.4353.79080216.597100.707803.231402.35300K562SF3A3
SPOPLENSG00000144228.4342.88890203.068300.755704.197402.97960K562SF3B1
SPOPLENSG00000144228.4364.58590221.911800.716206.203904.86900K562SRPK2
SPOPLENSG00000144228.4259.76570350.52790-0.432302.206701.56650K562SRSF1
SPOPLENSG00000144228.4566.97540270.583901.067103.719901.47570K562SUGP2
SPOPLENSG00000144228.4659.38130263.920401.320906.214803.84970K562SUPT6H
SPOPLENSG00000144228.4229.46830153.794800.577202.348101.41570K562SUPV3L1
SPOPLENSG00000144228.4510.24180321.884000.664502.888901.38210K562TAF15
SPOPLENSG00000144228.4259.01840354.77630-0.453902.336901.68410K562TARDBP
SPOPLENSG00000144228.4239.97510342.21670-0.512003.007002.14710K562TIA1
SPOPLENSG00000144228.4481.51250317.709500.599803.091801.92600K562U2AF1
SPOPLENSG00000144228.4486.11770328.175500.566704.600403.57200K562U2AF2
SPOPLENSG00000144228.4278.74090199.118700.485202.465001.63710K562WDR3
SPOPLENSG00000144228.4574.17800259.653201.144805.163402.66540K562YTHDC2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for SPOPL is not available on ENCORE database.





6 RBPs can affect the splicing of SPOPL :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SESPOPLENSG00000144228.4chr2+139322509139322563139322277139322420139326505139331117-0.139000.000000.00000excludedHepG2SF3A3
SESPOPLENSG00000144228.4chr2+1393120081393121051393101231393102511393165911393167690.115000.001700.09854includedHepG2TIAL1
SESPOPLENSG00000144228.4chr2+1393120081393121051393101231393102511393165911393167690.157000.000000.01498includedHepG2NIP7
A3SSSPOPLENSG00000144228.4chr2+139308472139308624139308543139308624139308052139308174-0.230000.000260.07043shorterHepG2HNRNPU
A3SSSPOPLENSG00000144228.4chr2+1393084721393086241393085431393086241393080521393081740.139000.000570.08306longerHepG2SFPQ
MXESPOPLENSG00000144228.4chr2+1393077261393078641393080521393081741392595011392596891393085431393086240.263000.002920.019691includedHepG2U2AF2

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for SPOPL is not avaliable on ENCORE database.