SMC6

General Information

Gene Name       : SMC6
Gene ID             : ENSG00000163029.15
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: SMC6)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878SMC6ENSG00000163029.1540.6233.5737.09ENCSR000AEF
HepG2SMC6ENSG00000163029.1518.2538.8428.55ENCSR985KAT
K562SMC6ENSG00000163029.1530.2337.4333.83ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for SMC6 is not avaliable on ENCORE database.



Proteins bound to RNA
  • SMC6 RNA is bound by 30 proteins.  







eCLIP assay for SMC6 is not avaliable on ENCORE database.





30 proteins are bound to SMC6 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr21788991717890014-3'-UTR,CDS,intron-Distal4.364345.37961K562YBX3
chr21788991617890005-3'-UTR,CDS,intron-Distal3.259655.73981HepG2GRWD1
chr21784666817846769-3'-UTR,intron-Distal,intron-Proximal5.202235.25980HepG2SUB1
chr21788848617888548-3'-UTR,CDS,intron-Distal,intron-Proximal4.554109.14010HepG2BCLAF1
chr21788996017890050-3'-UTR,CDS,intron-Distal,intron-Proximal3.268385.75231K562AQR
chr21788990717890020-3'-UTR,CDS,intron-Distal3.6412916.33569HepG2BCLAF1
chr21792719517927269-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.667408.07956K562SF3B4
chr21784641817846482-3'-UTR,intron-Distal4.4360412.07925K562PUM2
chr21784670917846746-3'-UTR,intron-Distal,intron-Proximal3.916555.35703HepG2BCLAF1
chr21792709317927227-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.054936.23779HepG2PPIG
chr21793496517935059-5'-UTR,intron-Distal,intron-Proximal3.165645.26712K562DDX3X
chr21793498517935077-5'-UTR,intron-Distal,intron-Proximal3.113915.54233K562FXR2
chr21793416117934273-5'-UTR,intron-Distal,intron-Proximal3.020844.18910HepG2TAF15
chr21793489217935035-5'-UTR,intron-Distal3.377433.66170HepG2DDX3X
chr21793498017935050-5'-UTR,intron-Distal,intron-Proximal4.033764.28220HepG2GRWD1
chr21793496317935083-5'-UTR,intron-Distal,intron-Proximal5.2916819.96796HepG2NCBP2
chr21793482317934919-5'-UTR,intron-Distal5.0107321.42455HepG2PRPF8
chr21793422517934290-5'-UTR,intron-Distal,intron-Proximal6.0718526.97527K562ZRANB2
chr21793491217934965-5'-UTR,intron-Distal3.243873.02717K562DDX3X
chr21793503517935071-5'-UTR,intron-Distal,intron-Proximal5.066684.57565HepG2DDX3X
chr21793480217934917-5'-UTR,intron-Distal3.3723011.89846K562PRPF8
chr21790652117906578-CDS,intron-Distal,intron-Proximal3.574775.19978HepG2BUD13
chr21789814717898170-CDS,intron-Distal4.950116.71715HepG2BCLAF1
chr21787642317876488-CDS,intron-Distal4.7566010.19430HepG2BCLAF1
chr21789735117897441-CDS,intron-Distal,intron-Proximal3.024999.58112K562UCHL5
chr21790245317902525-CDS,intron-Distal3.9484112.01397HepG2BCLAF1
chr21792709217927159-CDS,intron-Distal,intron-Proximal4.5490816.44038HepG2BCLAF1
chr21789622117896288-CDS,intron-Distal,intron-Proximal4.477557.97334HepG2BCLAF1
chr21785169917851745-CDS,intron-Distal3.725096.97808HepG2BCLAF1
chr21788152417881589-CDS,intron-Distal4.254077.09561HepG2BCLAF1
chr21791955717919594-CDS,intron-Distal,intron-Proximal3.687844.74886HepG2BCLAF1
chr21789835517898419-CDS,intron-Distal3.032054.01873K562UCHL5
chr21791292017913011-CDS,intron-Distal,intron-Proximal5.138506.75320K562AQR
chr21788147717881501-CDS,intron-Distal3.668163.68471HepG2BCLAF1
chr21791237117912407-CDS,intron-Distal,intron-Proximal3.955853.79347HepG2GRWD1
chr21792292717922998-CDS,intron-Distal,intron-Proximal3.143283.28147K562GRWD1
chr21790228217902306-CDS,intron-Distal,intron-Proximal3.203004.00731K562UCHL5
chr21786016317860221-CDS,intron-Distal3.613905.15500HepG2BCLAF1
chr21792287717922916-CDS,intron-Distal,intron-Proximal4.2250910.24470HepG2BCLAF1
chr21789940917899464-CDS,intron-Distal5.5128710.24913HepG2BCLAF1
chr21792712117927188-CDS,intron-Distal3.364645.74981HepG2GRWD1
chr21791300717913022-CDS,intron-Distal,intron-Proximal3.859825.36555HepG2BCLAF1
chr21785169617851751-CDS,intron-Distal3.786197.35414K562ZNF622
chr21786498617865029-CDS,intron-Distal5.012847.49801K562ZNF622
chr21791300617913036-CDS,intron-Distal,intron-Proximal4.003063.34184HepG2GRWD1
chr21790246417902528-CDS,intron-Distal4.5742620.36431K562UCHL5
chr21792298117922997-CDS,intron-Distal,intron-Proximal3.942759.42122K562ZNF622
chr21790240817902453-CDS,intron-Distal,intron-Proximal4.694759.74753HepG2BCLAF1
chr21790242517902504-CDS,intron-Distal3.406624.90323K562XRCC6
chr21790250017902529-CDS,intron-Distal,intron-Proximal4.7451810.62290K562ZNF622
chr21790647617906526-CDS,intron-Distal,intron-Proximal4.234825.97994K562AQR
chr21786013817860211-CDS,intron-Distal3.355414.02291HepG2GRWD1
chr21791235417912399-CDS,intron-Distal4.342055.00488K562LIN28B
chr21791951117919569-CDS,intron-Distal4.368645.40397K562LIN28B
chr21792294417922997-CDS,intron-Distal,intron-Proximal4.2640010.92483K562UCHL5
chr21787755417877592-CDS,intron-Distal,intron-Proximal4.854605.50697K562UCHL5
chr21789745517897529-CDS,intron-Distal5.8728210.24913HepG2BCLAF1
chr21789934317899384-CDS,intron-Distal,intron-Proximal5.159557.73487HepG2BCLAF1
chr21790652017906618-CDS,intron-Distal,intron-Proximal4.1262117.34376K562ZNF622
chr21789626817896332-CDS,intron-Distal3.339576.35635K562UCHL5
chr21788160517881624-CDS,intron-Distal4.442174.90367K562ZNF622
chr21788161417881644-CDS,intron-Distal3.837625.06180HepG2BCLAF1
chr21792291617922997-CDS,intron-Distal,intron-Proximal5.5324917.91413HepG2BCLAF1
chr21790240817902464-CDS,intron-Distal,intron-Proximal3.694257.05173K562ZNF622
chr21790240717902464-CDS,intron-Distal,intron-Proximal3.170817.93618K562UCHL5
chr21792709317927142-CDS,intron-Distal,intron-Proximal3.3651214.24825K562ZNF622
chr21790652217906592-CDS,intron-Distal,intron-Proximal4.740017.16838HepG2BCLAF1
chr21785168717851752-CDS,intron-Distal,intron-Proximal3.437444.41784HepG2GRWD1
chr21791304817913111-CDS,intron-Distal3.165308.02162HepG2BCLAF1
chr21791309217913145-CDS,intron-Distal,intron-Proximal3.406354.02291HepG2GRWD1
chr21785182117851836-CDS,intron-Distal3.102883.94979HepG2BCLAF1
chr21788309917883154-CDS,intron-Distal5.015066.23323K562UCHL5
chr21784768617847700-CDS,intron-Distal,intron-Proximal4.256603.71570HepG2BCLAF1
chr21787641817876495-CDS,intron-Distal,intron-Proximal4.501554.60638K562GRWD1
chr21791238517912406-CDS,intron-Distal3.321415.15500HepG2BCLAF1
chr21789802417898060-CDS,intron-Distal4.687845.23259HepG2BCLAF1
chr21789835417898423-CDS,intron-Distal,intron-Proximal4.9418611.54096HepG2BCLAF1
chr21787755817877596-CDS,intron-Distal4.848815.23259HepG2BCLAF1
chr21788443017884493-CDS,intron-Distal3.105655.53494HepG2BCLAF1
chr21789616117896189-CDS,intron-Distal,intron-Proximal3.387073.31745K562ZNF622
chr21791948717919515-CDS,intron-Distal,intron-Proximal5.530347.95223HepG2BCLAF1
chr21789738817897455-CDS,intron-Distal4.007559.08790HepG2BCLAF1
chr21790244717902521-CDS,intron-Distal3.058875.99913K562GRWD1
chr21790252117902528-CDS,intron-Distal3.451014.37145K562GRWD1
chr21787642017876501-CDS,intron-Distal3.556584.45064HepG2GRWD1
chr21788309517883119-CDS,intron-Distal,intron-Proximal3.438445.45876HepG2BCLAF1
chr21789841917898442-CDS,intron-Distal4.087266.11943K562UCHL5
chr21792295417922981-CDS,intron-Distal5.205798.87880K562ZNF622
chr21790228617902307-CDS,intron-Distal,intron-Proximal4.922596.04243HepG2BCLAF1
chr21789842317898444-CDS,intron-Distal,intron-Proximal5.215078.40988HepG2BCLAF1
chr21788449817884557-CDS,intron-Distal5.404328.41647HepG2BCLAF1
chr21788155417881646-CDS,intron-Distal,intron-Proximal4.5511110.38007K562UCHL5
chr21791311117913144-CDS,intron-Distal5.5931110.24913HepG2BCLAF1
chr21790652117906586-CDS,intron-Distal,intron-Proximal3.5751814.94527K562UCHL5
chr21789735117897383-CDS,intron-Distal,intron-Proximal4.2582811.11870HepG2BCLAF1
chr21791948717919538-CDS,intron-Distal,intron-Proximal3.351553.60157HepG2GRWD1
chr21792293517923000-CDS,intron-Distal,intron-Proximal3.832064.52024HepG2PPIG
chr21787641817876486-CDS,intron-Distal,intron-Proximal5.6927911.31313K562ZNF622
chr21792709217927155-CDS,intron-Distal,intron-Proximal3.2853111.00019K562UCHL5
chr21789946417899490-CDS,intron-Distal3.991344.46864HepG2BCLAF1
chr21789812917898171-CDS,intron-Distal3.259584.59873K562UCHL5
chr21789835317898441-CDS,intron-Distal,intron-Proximal3.351354.58459K562GRWD1
chr21792866917928727-intron-Distal3.061355.10412K562KHDRBS1
chr21793480217934892-intron-Distal3.392175.97015HepG2EFTUD2
chr21792113517921234-intron-Distal4.509484.35455K562EIF4G2
chr21793155217931625-intron-Distal4.8526814.82176K562QKI
chr21788323417883302-intron-Distal,intron-Proximal3.950793.24603K562KHSRP
chr21793142817931553-intron-Distal5.1406114.02358K562PTBP1
chr21793480717934893-intron-Distal4.336149.03062K562AQR
chr21793142917931553-intron-Distal4.1225620.22542HepG2QKI
chr21790633217906417-intron-Distal3.724583.45805K562KHSRP
chr21790830517908452-intron-Distal3.739425.79722K562HNRNPL
chr21786618417866352-intron-Distal3.893086.86368K562PTBP1
chr21787544317875535-intron-Distal4.102044.93238K562QKI
chr21793155317931617-intron-Distal5.0872822.27673HepG2QKI
chr21793472217934777-intron-Distal3.752914.95247K562PRPF8
chr21786471217864825-intron-Distal,intron-Proximal4.281204.22101K562PRPF8
chr21793444617934497-intron-Distal3.308123.68839K562KHSRP
chr21793150917931552-intron-Distal3.5212711.54482K562QKI
chr21785304717853243-intron-Distal3.720303.26999K562KHSRP
chr21793457517934656-intron-Distal3.224605.60501HepG2HNRNPK
chr21793463217934746-intron-Distal3.651324.20652K562DGCR8
chr21791248017912624-intron-Distal,intron-Proximal3.298195.42680K562KHSRP
chr21792983617929971-intron-Distal3.046755.66512K562KHDRBS1
chr21792102717921135-intron-Distal4.844415.59072K562EIF4G2
chr21791223217912327-intron-Distal,intron-Proximal5.152458.34848K562PRPF8
chr21787746217877534-intron-Distal,intron-Proximal4.184883.31283K562PRPF8
chr21787542717875500-intron-Distal4.506824.30850HepG2QKI
chr21793433117934388-intron-Distal,intron-Proximal4.542019.22974HepG2SF3A3
chr21793417617934208-intron-Distal,intron-Proximal5.550797.14812K562ZRANB2
chr21792970817929743-intron-Distal3.119493.29213HepG2KHSRP
chr21793480917934866-intron-Distal3.293863.93112K562RBM15
chr21790778417907910-intron-Distal,intron-Proximal3.362906.39618K562KHSRP
chr21789820617898314-intron-Distal,intron-Proximal3.720303.02234K562KHSRP
chr21785028617850363-intron-Distal4.393086.59655K562PTBP1
chr21793143217931552-intron-Distal4.1977113.15528HepG2PTBP1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for SMC6 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for SMC6 is not available on ENCORE database.

  • 92 RBPs can affect the levels of SMC6.  








The Knockdown/knockout RNA-Seq assay for SMC6 is not available on ENCORE database.





92 RBPs can affect the gene expression of SMC6 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
SMC6ENSG00000163029.111616.852401251.532000.369403.078401.95430HepG2AATF
SMC6ENSG00000163029.112015.162101606.258500.327105.236004.45240HepG2ACO1
SMC6ENSG00000163029.112134.228201464.733100.543004.620603.95620HepG2AKAP1
SMC6ENSG00000163029.111277.303201613.94050-0.337504.424903.47070HepG2AKAP8L
SMC6ENSG00000163029.111038.559801397.56860-0.428302.526001.66640HepG2BCLAF1
SMC6ENSG00000163029.111865.303303822.33560-1.0350023.1329021.66960HepG2BOP1
SMC6ENSG00000163029.111250.126701606.07220-0.361505.972805.06370HepG2CKAP4
SMC6ENSG00000163029.111692.322003509.18210-1.0521016.8770015.34580HepG2CPSF6
SMC6ENSG00000163029.111004.975501337.26070-0.412104.957803.59700HepG2YBX3
SMC6ENSG00000163029.111772.285202178.02720-0.297405.131604.16820HepG2DAZAP1
SMC6ENSG00000163029.111148.602501485.63380-0.371205.899604.74400HepG2DDX19B
SMC6ENSG00000163029.11953.073201266.43390-0.410103.652602.53350HepG2DHX30
SMC6ENSG00000163029.11916.272301313.02520-0.519007.620906.50040HepG2DNAJC21
SMC6ENSG00000163029.111004.334701301.52470-0.374005.811904.91860HepG2DNAJC2
SMC6ENSG00000163029.111382.530702058.28010-0.574106.963505.69630HepG2EIF4G2
SMC6ENSG00000163029.112058.775702686.12960-0.383706.316805.47060HepG2ETF1
SMC6ENSG00000163029.111101.32070717.575200.617907.152605.92620HepG2FUBP3
SMC6ENSG00000163029.111714.898501291.800800.408603.215402.47100HepG2FXR1
SMC6ENSG00000163029.111768.201201272.135300.474904.328903.20360HepG2G3BP2
SMC6ENSG00000163029.112400.807103978.12280-0.728609.307508.17750HepG2GPKOW
SMC6ENSG00000163029.111075.967801474.52210-0.454604.412903.55190HepG2HNRNPC
SMC6ENSG00000163029.111452.567802236.40980-0.622607.663306.54910HepG2HNRNPF
SMC6ENSG00000163029.111571.673401213.149500.373403.043302.31220HepG2HNRNPK
SMC6ENSG00000163029.111247.857201984.05780-0.6690020.5286018.85590HepG2HNRNPL
SMC6ENSG00000163029.112382.134103796.37850-0.672406.306705.40010HepG2HNRNPLL
SMC6ENSG00000163029.111318.961002202.25450-0.739606.091605.05820HepG2IGF2BP1
SMC6ENSG00000163029.111186.520901468.42290-0.307503.690602.51300HepG2KIF1C
SMC6ENSG00000163029.111987.518201292.250100.621004.804803.94800HepG2MAGOH
SMC6ENSG00000163029.112239.005401299.546500.784709.279908.18090HepG2MATR3
SMC6ENSG00000163029.111596.470601184.877100.430003.380202.58740HepG2PABPC4
SMC6ENSG00000163029.111269.995601086.906900.224502.056801.52090HepG2PCBP1
SMC6ENSG00000163029.111091.904701306.45340-0.258802.321501.63970HepG2PPIL4
SMC6ENSG00000163029.111680.712101105.976700.6037012.4575011.46210HepG2PTBP1
SMC6ENSG00000163029.111186.762702061.60350-0.7967014.3970013.18070HepG2PUF60
SMC6ENSG00000163029.111693.548602186.86770-0.368804.513403.66790HepG2PUM2
SMC6ENSG00000163029.111378.118801636.10230-0.247602.965202.33330HepG2PUS1
SMC6ENSG00000163029.111976.547301197.782500.7225014.5000013.22690HepG2QKI
SMC6ENSG00000163029.112452.761501568.543300.644903.868303.03860HepG2RAVER1
SMC6ENSG00000163029.111934.614501087.071300.831508.594507.45610HepG2RBM25
SMC6ENSG00000163029.112112.781201230.839000.7794021.0150019.79620HepG2NELFE
SMC6ENSG00000163029.111770.147901146.371800.6267013.5055012.30060HepG2RECQL
SMC6ENSG00000163029.111746.812602408.72260-0.463504.540403.69420HepG2RPLP0
SMC6ENSG00000163029.112730.151101705.916900.678304.135502.24490HepG2RTF1
SMC6ENSG00000163029.111082.354401304.42510-0.269202.619801.99050HepG2SAFB2
SMC6ENSG00000163029.112882.599703757.77520-0.382502.358101.70390HepG2SF3B1
SMC6ENSG00000163029.111788.420701151.449700.6351013.7398012.57820HepG2SF3B4
SMC6ENSG00000163029.111653.902001976.66460-0.257203.779302.97940HepG2SLBP
SMC6ENSG00000163029.111814.345701521.149200.254203.611902.89350HepG2SMN1
SMC6ENSG00000163029.112439.169904181.14430-0.777506.731305.50590HepG2SNRNP70
SMC6ENSG00000163029.112290.518201201.870300.9303032.2369031.01070HepG2SRSF1
SMC6ENSG00000163029.111277.793002197.09740-0.781909.185008.04640HepG2SRSF7
SMC6ENSG00000163029.111213.23980977.790700.311203.583902.97370HepG2SRSF9
SMC6ENSG00000163029.112260.634901080.304701.0652033.8246032.14460HepG2TAF15
SMC6ENSG00000163029.112124.434503699.78620-0.8004014.2312012.79150HepG2TARDBP
SMC6ENSG00000163029.111420.82330992.635000.517306.602705.31720HepG2TIA1
SMC6ENSG00000163029.111011.391501423.18190-0.492806.212605.51660HepG2TIAL1
SMC6ENSG00000163029.111068.396101436.02970-0.426606.713605.90260HepG2TRIM56
SMC6ENSG00000163029.111532.775502014.02630-0.393904.424403.28770HepG2TUFM
SMC6ENSG00000163029.113441.245101795.735200.938307.942006.88110HepG2U2AF1
SMC6ENSG00000163029.111486.024002067.97970-0.4768010.001208.81770HepG2UPF1
SMC6ENSG00000163029.112406.002401996.554200.269003.642002.97090HepG2UTP3
SMC6ENSG00000163029.112582.509301542.020800.743906.530104.60790HepG2XRCC5
SMC6ENSG00000163029.112343.659501724.754300.442302.626301.59740HepG2XRCC6
SMC6ENSG00000163029.113352.494103779.01830-0.172801.999801.50220K562AGGF1
SMC6ENSG00000163029.112779.907203932.22680-0.500306.630805.58680K562AKAP8L
SMC6ENSG00000163029.112409.600204388.15140-0.8648017.3898016.08170K562AQR
SMC6ENSG00000163029.113020.451504484.70390-0.570203.727102.71280K562BOP1
SMC6ENSG00000163029.114192.071105374.01880-0.358306.352004.63830K562CPEB4
SMC6ENSG00000163029.113204.937604768.72160-0.573305.329104.24840K562CPSF6
SMC6ENSG00000163029.111672.057902219.61840-0.408704.687203.27730K562DDX3X
SMC6ENSG00000163029.111729.302402250.42090-0.380005.219703.23570K562DDX6
SMC6ENSG00000163029.111930.591802438.15130-0.336705.075503.41270K562EIF2S1
SMC6ENSG00000163029.112539.084503239.76540-0.351603.981603.14360K562EIF2S2
SMC6ENSG00000163029.111708.684002088.40700-0.289502.828801.65700K562EIF4B
SMC6ENSG00000163029.111621.471502024.26170-0.320103.529102.04170K562EWSR1
SMC6ENSG00000163029.112459.847404235.08710-0.783803.654302.66960K562FIP1L1
SMC6ENSG00000163029.114100.093502637.993200.636105.829804.71730K562G3BP2
SMC6ENSG00000163029.113125.942004553.11120-0.542604.854003.80510K562GPKOW
SMC6ENSG00000163029.112911.732004317.66760-0.568406.382305.22720K562GRSF1
SMC6ENSG00000163029.111296.472302490.88800-0.942109.389308.34180K562HNRNPC
SMC6ENSG00000163029.113707.881405025.26240-0.438606.044704.42330K562HNRNPL
SMC6ENSG00000163029.112168.802903482.99590-0.683402.363501.50630K562HNRNPM
SMC6ENSG00000163029.113460.818302970.656000.220202.285101.47170K562HNRNPU
SMC6ENSG00000163029.112335.667802980.45720-0.351702.337701.41700K562IGF2BP2
SMC6ENSG00000163029.113032.108904444.27890-0.551604.755403.58880K562METAP2
SMC6ENSG00000163029.113196.737703857.81410-0.271204.533603.52010K562MTPAP
SMC6ENSG00000163029.113521.800404286.39900-0.283507.541806.39380K562NSUN2
SMC6ENSG00000163029.112673.127704682.34530-0.808702.899501.87900K562PABPN1
SMC6ENSG00000163029.113039.190104807.05050-0.661502.963002.10990K562PPIG
SMC6ENSG00000163029.112910.241205569.45950-0.936402.948001.43420K562PPP1R8
SMC6ENSG00000163029.115657.533206485.70580-0.197102.238201.37310K562PUM2
SMC6ENSG00000163029.113044.285603899.78350-0.357303.586002.97950K562PUS1
SMC6ENSG00000163029.113170.224903799.67410-0.261303.076602.45700K562RBM15
SMC6ENSG00000163029.112275.505002919.33590-0.359503.427902.48710K562RBM22
SMC6ENSG00000163029.112401.215904283.68990-0.835102.389301.30530K562SF1
SMC6ENSG00000163029.113614.289504229.55060-0.226802.703901.89840K562SF3A3
SMC6ENSG00000163029.113034.595805224.58010-0.783802.594001.34930K562SFPQ
SMC6ENSG00000163029.111414.947401931.01360-0.448602.888401.83360K562SRFBP1
SMC6ENSG00000163029.112288.793202817.99540-0.300102.502301.51100K562SRSF5
SMC6ENSG00000163029.112915.729002356.888100.306903.435502.52180K562SYNCRIP
SMC6ENSG00000163029.112002.123203020.28540-0.593205.837304.78380K562TARDBP
SMC6ENSG00000163029.112237.494402913.35190-0.380804.549903.46240K562TIA1
SMC6ENSG00000163029.111546.948102148.05490-0.473603.432402.38520K562TIAL1
SMC6ENSG00000163029.111511.873802281.36550-0.593605.205903.80780K562TRIM56
SMC6ENSG00000163029.113512.443602558.236600.457204.018602.65140K562U2AF1
SMC6ENSG00000163029.113378.178302641.720800.354704.570003.54360K562U2AF2
SMC6ENSG00000163029.113822.516604544.95810-0.249704.248003.37650K562UPF1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for SMC6 is not available on ENCORE database.





28 RBPs can affect the splicing of SMC6 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SESMC6ENSG00000163029.11chr2-1786330917863366178601251786023117864904178650300.068000.000000.00005includedK562SRSF1
SESMC6ENSG00000163029.11chr2-1793424417934331179270931792721817934892179350400.297000.000080.00474includedK562PRPF8
SESMC6ENSG00000163029.11chr2-179342441793433117927093179272181793489217935040-0.337000.000000.00004excludedHepG2RBM22
SESMC6ENSG00000163029.11chr2-1789465117894847178899051789002017896127178961440.153000.000040.05471includedHepG2IGF2BP1
SESMC6ENSG00000163029.11chr2-1789465117894847178899051789002017896127178961440.070000.000170.00793includedK562AKAP8L
SESMC6ENSG00000163029.11chr2-179076551790773617906523179066251791234417912406-0.071000.001200.03647excludedK562AKAP8L
SESMC6ENSG00000163029.11chr2-1793424417934331179271041792721817934892179350400.264000.000190.02836includedK562FMR1
SESMC6ENSG00000163029.11chr2-1793424417934331179270931792721817934892179350400.219000.000680.01011includedHepG2U2AF2
SESMC6ENSG00000163029.11chr2-1793424417934331179270931792721817934892179350400.377000.000000.00001includedK562AQR
SESMC6ENSG00000163029.11chr2-1793424417934331179270931792721817934892179350400.234000.000340.01686includedK562FXR1
SESMC6ENSG00000163029.11chr2-1793424417934331179270931792721817934892179350400.260000.000550.04622includedK562SUPV3L1
SESMC6ENSG00000163029.11chr2-1789465117894847178899051789002017896127178961440.065000.000670.01225includedK562PUS1
SESMC6ENSG00000163029.11chr2-179076551790773617906523179066251791234417912406-0.091000.000060.00160excludedK562PUS1
SESMC6ENSG00000163029.11chr2-1793426817934331179270931792721817934892179350400.110000.000000.00006includedHepG2SFPQ
SESMC6ENSG00000163029.11chr2-1789465117894847178899051789002017896127178961440.077000.001300.05476includedHepG2SFPQ
SESMC6ENSG00000163029.11chr2-179342441793433117927104179272181793489217935040-0.264000.000110.06192excludedHepG2UPF1
SESMC6ENSG00000163029.11chr2-1793424417934331179270931792721817934892179350400.161000.000000.00002includedK562LARP4
SESMC6ENSG00000163029.11chr2-1793424417934331179270931792721817934892179350400.237000.001500.06884includedK562EFTUD2
SESMC6ENSG00000163029.11chr2-1793426817934331179270931792721817934892179350400.177000.000080.06911includedK562DDX21
SESMC6ENSG00000163029.11chr2-1793426817934331179270931792721817934892179350400.087000.000010.00445includedHepG2HNRNPUL1
SESMC6ENSG00000163029.11chr2-1793424417934331179270931792721817934892179350400.138000.000010.01107includedK562PPIL4
SESMC6ENSG00000163029.11chr2-1793424417934331179270931792721817934892179350400.150000.000010.00548includedK562SBDS
SESMC6ENSG00000163029.11chr2-1793426817934331179270931792721817934892179350400.193000.000730.09705includedK562SRSF7
SESMC6ENSG00000163029.11chr2-179076551790773617906523179066251791234417912406-0.077000.000120.00674excludedK562UTP18
SESMC6ENSG00000163029.11chr2-1793424417934331179270931792721817934892179350400.161000.000990.03737includedK562HNRNPU
SESMC6ENSG00000163029.11chr2-1789465117894847178899051789002017896127178961440.066000.000320.01103includedK562RBM15
SESMC6ENSG00000163029.11chr2-178601251786023117851689178518421786490417865030-0.052000.000070.00322excludedK562RBM15
SESMC6ENSG00000163029.11chr2-179076551790773617906523179066251791234417912406-0.086000.000050.00252excludedK562AGGF1
SESMC6ENSG00000163029.11chr2-1793427817934331179270931792721817934892179350700.164000.002830.08776includedK562PTBP1
SESMC6ENSG00000163029.11chr2-1789465117894847178899051789002017896127178961440.083000.000390.00875includedK562HNRNPC
SESMC6ENSG00000163029.11chr2-1793424417934331179270931792721817934892179350400.249000.001800.03111includedK562HNRNPC
MXESMC6ENSG00000163029.11chr2-17898354178984431789934317899490178980071789817217902206179023050.091000.010490.095341includedK562U2AF2
MXESMC6ENSG00000163029.11chr2-1790765517907723179123441791240617906523179066251791300717913144-0.190000.003840.098952includedHepG2BCCIP
MXESMC6ENSG00000163029.11chr2-1790765517907736179123441791240617906523179066251791300717913144-0.103000.003730.088872includedK562TAF15

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for SMC6 is not avaliable on ENCORE database.