SLC12A6

General Information

Gene Name       : SLC12A6
Gene ID             : ENSG00000140199.11
Essential Gene : No

Functions

Localization

Domains (AlphaFold: SLC12A6)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878SLC12A6ENSG00000140199.1138.9735.6237.30ENCSR000AEF
HepG2SLC12A6ENSG00000140199.1110.7211.8111.27ENCSR985KAT
K562SLC12A6ENSG00000140199.116.836.866.85ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for SLC12A6 is not avaliable on ENCORE database.



Proteins bound to RNA
  • SLC12A6 RNA is bound by 8 proteins.  







eCLIP assay for SLC12A6 is not avaliable on ENCORE database.





8 proteins are bound to SLC12A6 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr153455314034553218-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal5.404328.41647HepG2BCLAF1
chr153452821434528244-3'-UTR,CDS,intron-Distal,intron-Proximal4.611845.23259HepG2BCLAF1
chr153453623534536258-CDS,intron-Distal3.337623.27569HepG2BCLAF1
chr153453344834533486-CDS,intron-Distal3.676665.97823HepG2BCLAF1
chr153454658634546671-CDS,intron-Distal4.491924.31428K562YBX3
chr153453301934533069-CDS,intron-Distal,intron-Proximal5.181027.88130HepG2U2AF2
chr153453112934531202-CDS,intron-Distal,intron-Proximal5.162807.26081HepG2PRPF8
chr153454289134542937-CDS,intron-Distal,intron-Proximal4.444053.35169HepG2U2AF2
chr153454748734547504-CDS,intron-Distal4.165303.45943HepG2BCLAF1
chr153460256934602611-intron-Distal4.2797515.99521HepG2HNRNPL
chr153460273834602802-intron-Distal5.546388.56354HepG2AGGF1
chr153453322934533291-intron-Distal,intron-Proximal5.7307810.40229HepG2U2AF2
chr153460267734602733-intron-Distal5.3879629.23634HepG2HNRNPL
chr153460235434602430-intron-Distal4.7181314.81478K562HNRNPL
chr153455799234558120-intron-Distal4.699634.07628HepG2PTBP1
chr153459350434593565-intron-Distal3.885023.63454HepG2SUGP2
chr153460243234602451-intron-Distal5.6486239.52680HepG2HNRNPL
chr153460251034602535-intron-Distal5.6888612.50513HepG2HNRNPL
chr153460256134602569-intron-Distal3.6144510.99111HepG2HNRNPL
chr153460235534602375-intron-Distal4.451585.63915HepG2AGGF1
chr153460290134602958-intron-Distal3.638795.12089K562HNRNPL
chr153460237534602430-intron-Distal4.4731113.95542HepG2AGGF1
chr153460242734602474-intron-Distal6.3776616.62195K562AGGF1
chr153460235734602427-intron-Distal5.0639922.03024K562AGGF1
chr153453320034533233-intron-Distal,intron-Proximal3.741304.93978HepG2BCLAF1
chr153460273334602788-intron-Distal4.436035.63065K562HNRNPL
chr153460235934602432-intron-Distal7.0016776.36970HepG2HNRNPL
chr153460249634602510-intron-Distal5.6888612.50513HepG2HNRNPL
chr153460225034602343-intron-Distal4.314497.30217HepG2AGGF1
chr153460273334602750-intron-Distal4.9261213.56318HepG2HNRNPL
chr153460243034602471-intron-Distal3.443129.34488HepG2AGGF1
chr153459359034593642-intron-Distal3.985843.79098HepG2SUGP2
chr153460290034602956-intron-Distal5.0985837.44381HepG2HNRNPL
chr153460290334602950-intron-Distal3.249094.24070HepG2AGGF1
chr153460243034602475-intron-Distal4.102749.03470K562HNRNPL
chr153460290034602956-intron-Distal4.090258.43371K562AGGF1
chr153460275034602796-intron-Distal3.7576114.02093HepG2HNRNPL
chr153460245134602476-intron-Distal5.6338726.09761HepG2HNRNPL
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for SLC12A6 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for SLC12A6 is not available on ENCORE database.

  • 109 RBPs can affect the levels of SLC12A6.  








The Knockdown/knockout RNA-Seq assay for SLC12A6 is not available on ENCORE database.





109 RBPs can affect the gene expression of SLC12A6 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
SLC12A6ENSG00000140199.7596.11490853.08320-0.517107.068806.18810HepG2ACO1
SLC12A6ENSG00000140199.7571.857801505.64870-1.396709.646508.71880HepG2AKAP1
SLC12A6ENSG00000140199.7548.310701245.86890-1.184108.015906.71650HepG2ASCC1
SLC12A6ENSG00000140199.7211.82630573.27670-1.4363014.8385012.54990HepG2BCCIP
SLC12A6ENSG00000140199.7656.02430498.177000.397002.410801.57350HepG2BCLAF1
SLC12A6ENSG00000140199.71034.43700852.816100.278402.946602.26500HepG2CKAP4
SLC12A6ENSG00000140199.7668.48860992.41750-0.570003.053502.24670HepG2CNOT7
SLC12A6ENSG00000140199.7534.57960739.70270-0.468503.166402.43570HepG2CPSF6
SLC12A6ENSG00000140199.7563.75380738.68900-0.389903.582902.87050HepG2CELF1
SLC12A6ENSG00000140199.7437.72250711.83110-0.701508.492806.64120HepG2DDX1
SLC12A6ENSG00000140199.7924.842301442.44990-0.641203.334802.65630HepG2DDX3X
SLC12A6ENSG00000140199.71343.23910924.602500.538705.330803.97190HepG2DDX5
SLC12A6ENSG00000140199.7851.96140673.211500.339602.340901.44110HepG2DHX30
SLC12A6ENSG00000140199.7549.37710697.99280-0.345402.740202.03930HepG2DNAJC21
SLC12A6ENSG00000140199.7505.71260691.82040-0.452105.332404.47050HepG2DNAJC2
SLC12A6ENSG00000140199.7881.240901191.18260-0.434801.923201.41880HepG2EIF2S1
SLC12A6ENSG00000140199.7651.81260836.56280-0.360002.897101.69930HepG2EIF2S2
SLC12A6ENSG00000140199.7857.521301281.53600-0.579603.003502.28920HepG2EIF4B
SLC12A6ENSG00000140199.7889.196901173.30650-0.400004.497803.76540HepG2ETF1
SLC12A6ENSG00000140199.7670.59220833.54220-0.313802.168601.42970HepG2EWSR1
SLC12A6ENSG00000140199.7509.15820701.52600-0.462403.575102.29920HepG2FASTKD2
SLC12A6ENSG00000140199.71066.40560842.745500.339502.557901.80090HepG2FUBP3
SLC12A6ENSG00000140199.7825.668301232.04210-0.577402.864802.18810HepG2G3BP1
SLC12A6ENSG00000140199.7386.83420596.28540-0.624305.094503.87380HepG2GEMIN5
SLC12A6ENSG00000140199.7560.53840747.05900-0.414402.291201.36770HepG2GNB2L1
SLC12A6ENSG00000140199.71625.50400838.567700.9548012.8934011.60700HepG2GPKOW
SLC12A6ENSG00000140199.7533.14330854.64730-0.680804.089902.20880HepG2GTF2F1
SLC12A6ENSG00000140199.71145.41480744.894300.6207010.138408.87470HepG2HNRNPF
SLC12A6ENSG00000140199.7697.279501246.91450-0.838605.548804.58610HepG2HNRNPK
SLC12A6ENSG00000140199.71299.31970800.255500.699107.907106.90440HepG2HNRNPLL
SLC12A6ENSG00000140199.7384.71300768.29430-0.9979013.7522011.90090HepG2HNRNPM
SLC12A6ENSG00000140199.7646.72290778.64090-0.267802.171301.62730HepG2HNRNPU
SLC12A6ENSG00000140199.71234.93310733.502000.7515011.3902010.01860HepG2IGF2BP1
SLC12A6ENSG00000140199.7473.95930661.27950-0.480503.184401.41460HepG2CCAR2
SLC12A6ENSG00000140199.7917.646101245.41030-0.440602.716101.89440HepG2LARP4
SLC12A6ENSG00000140199.7454.79500731.72950-0.686106.274004.58640HepG2LARP7
SLC12A6ENSG00000140199.7486.52720768.54540-0.659604.609403.03260HepG2LIN28B
SLC12A6ENSG00000140199.7932.894601328.30320-0.509802.336401.73200HepG2MAGOH
SLC12A6ENSG00000140199.7642.84260901.13730-0.487304.844603.79490HepG2MSI2
SLC12A6ENSG00000140199.71240.31360816.031700.603902.907701.91080HepG2MTPAP
SLC12A6ENSG00000140199.71129.29310756.769400.577404.662903.08920HepG2NAA15
SLC12A6ENSG00000140199.7964.557301367.35720-0.503502.471901.87130HepG2NCBP2
SLC12A6ENSG00000140199.7945.815701487.55010-0.653304.878502.97880HepG2NKRF
SLC12A6ENSG00000140199.7579.36840787.65780-0.443104.280703.33240HepG2NOL12
SLC12A6ENSG00000140199.71541.86000709.538001.1196020.2088018.42980HepG2NSUN2
SLC12A6ENSG00000140199.7484.11710743.41480-0.618804.454301.89910HepG2NUSAP1
SLC12A6ENSG00000140199.71725.08920907.192600.927102.219101.43970HepG2PABPC1
SLC12A6ENSG00000140199.7569.92730770.72490-0.435404.538203.48340HepG2PARN
SLC12A6ENSG00000140199.7783.381801188.93650-0.601906.199505.34680HepG2PCBP1
SLC12A6ENSG00000140199.71332.11640798.435800.738407.188506.01060HepG2PRPF4
SLC12A6ENSG00000140199.7981.386501209.73370-0.301803.488002.88910HepG2PTBP1
SLC12A6ENSG00000140199.7517.91660798.12340-0.623909.956308.97760HepG2PUM1
SLC12A6ENSG00000140199.71249.45300868.908600.523909.106808.09670HepG2PUS1
SLC12A6ENSG00000140199.71876.468701310.285700.518005.914905.04960HepG2QKI
SLC12A6ENSG00000140199.71493.021701227.597700.282302.707301.85740HepG2RBM15
SLC12A6ENSG00000140199.71392.52300980.673000.505807.517106.76150HepG2RBM22
SLC12A6ENSG00000140199.7497.05050882.31770-0.827908.346806.62060HepG2RBM27
SLC12A6ENSG00000140199.7762.649301346.36200-0.8200018.2223017.07190HepG2NELFE
SLC12A6ENSG00000140199.7810.426701253.87250-0.629608.750007.74590HepG2RECQL
SLC12A6ENSG00000140199.71672.20350802.526801.059007.652106.60270HepG2RPLP0
SLC12A6ENSG00000140199.7417.86970651.63340-0.641006.067305.19770HepG2RPS19
SLC12A6ENSG00000140199.7533.49660813.78220-0.609204.684703.65870HepG2RPS2
SLC12A6ENSG00000140199.7699.94580996.91440-0.510203.095102.25080HepG2RPS3A
SLC12A6ENSG00000140199.7572.45650830.63960-0.537103.935302.63780HepG2RPS5
SLC12A6ENSG00000140199.7596.06940430.236600.470202.831102.03650HepG2RRP9
SLC12A6ENSG00000140199.7446.82340654.03670-0.549703.921002.80260HepG2SERBP1
SLC12A6ENSG00000140199.7884.805401365.76170-0.626301.965401.39510HepG2SF3A3
SLC12A6ENSG00000140199.71394.71730792.127800.8161011.5791010.22860HepG2SF3B1
SLC12A6ENSG00000140199.71274.17600720.884600.8216020.9261019.34500HepG2SLBP
SLC12A6ENSG00000140199.7497.18240808.64300-0.7017012.0772010.87960HepG2SMN1
SLC12A6ENSG00000140199.7531.94910844.36460-0.666604.487303.24440HepG2SMNDC1
SLC12A6ENSG00000140199.71335.022801107.644300.269302.966802.45380HepG2SRFBP1
SLC12A6ENSG00000140199.7977.032101314.69490-0.428306.227705.58830HepG2SRSF1
SLC12A6ENSG00000140199.71050.19360731.855500.520907.041206.01260HepG2SRSF7
SLC12A6ENSG00000140199.7826.235701069.54050-0.372404.676403.99430HepG2SRSF9
SLC12A6ENSG00000140199.71590.85490961.715500.7260017.2087016.15850HepG2SSB
SLC12A6ENSG00000140199.71161.224401563.90480-0.429502.937901.61790HepG2SSRP1
SLC12A6ENSG00000140199.71026.57350844.264200.282002.684102.06910HepG2SUCLG1
SLC12A6ENSG00000140199.7413.08770561.11840-0.441901.902201.32740HepG2SUPV3L1
SLC12A6ENSG00000140199.71644.790701181.590100.477106.812306.00120HepG2TAF15
SLC12A6ENSG00000140199.71028.767201536.11560-0.578402.328501.34900HepG2TBRG4
SLC12A6ENSG00000140199.7594.75500756.60620-0.347202.574302.08930HepG2TIAL1
SLC12A6ENSG00000140199.7562.67940763.35790-0.440004.832104.12890HepG2TRIM56
SLC12A6ENSG00000140199.7204.95790331.49480-0.693703.946503.03930HepG2UCHL5
SLC12A6ENSG00000140199.7230.28080513.90870-1.158108.120406.35650HepG2UPF2
SLC12A6ENSG00000140199.7871.510101169.38600-0.424205.628004.82290HepG2UTP3
SLC12A6ENSG00000140199.7584.47730892.95960-0.611404.032902.70550HepG2XPO5
SLC12A6ENSG00000140199.7345.09010552.35840-0.678604.301703.40350HepG2XRN2
SLC12A6ENSG00000140199.7883.799001332.11160-0.5919013.1215012.15350HepG2ZNF622
SLC12A6ENSG00000140199.7517.78750892.57370-0.7856012.9721011.84170K562AGGF1
SLC12A6ENSG00000140199.7729.97470980.75510-0.426003.616902.45530K562AKAP8
SLC12A6ENSG00000140199.7637.50740928.75150-0.542905.198704.29100K562AKAP8L
SLC12A6ENSG00000140199.7773.02450974.46140-0.334103.098402.12870K562ATP5C1
SLC12A6ENSG00000140199.7510.04920356.484600.516703.150602.21820K562BOP1
SLC12A6ENSG00000140199.7512.09410379.063500.433902.766901.98490K562CPSF6
SLC12A6ENSG00000140199.7560.56690999.47800-0.8343015.2624012.85610K562DKC1
SLC12A6ENSG00000140199.7574.99460361.623500.669007.363806.27250K562EIF2S2
SLC12A6ENSG00000140199.7440.34340258.373500.769104.037602.76000K562EIF3D
SLC12A6ENSG00000140199.7510.86180385.653200.405502.239501.46740K562FMR1
SLC12A6ENSG00000140199.7295.97230481.94040-0.703405.228404.18440K562GRSF1
SLC12A6ENSG00000140199.7581.80110807.99490-0.473804.650102.13570K562CCAR2
SLC12A6ENSG00000140199.7725.14960985.67930-0.442803.667002.69920K562KIF1C
SLC12A6ENSG00000140199.7443.08250309.002500.519902.453201.57980K562KRR1
SLC12A6ENSG00000140199.7350.01700482.33700-0.462603.154102.25530K562MAGOH
SLC12A6ENSG00000140199.7366.45660481.33520-0.393402.487601.61630K562MATR3
SLC12A6ENSG00000140199.7754.336001104.20390-0.549706.620305.09910K562MBNL1
SLC12A6ENSG00000140199.7567.22490773.96330-0.448302.382201.57710K562NAA15
SLC12A6ENSG00000140199.7541.61370442.926200.290102.092701.43370K562NSUN2
SLC12A6ENSG00000140199.7680.40360434.278600.647704.859103.76010K562PCBP3
SLC12A6ENSG00000140199.7582.38930333.107800.805904.439803.42210K562POLR2G
SLC12A6ENSG00000140199.7204.63270305.73250-0.579202.775601.87020K562PSIP1
SLC12A6ENSG00000140199.7652.84090921.15210-0.496703.795203.17330K562PUS1
SLC12A6ENSG00000140199.7513.04160897.45310-0.8068012.1823010.94150K562RBM15
SLC12A6ENSG00000140199.7896.36120527.132800.765802.917801.32980K562RBM39
SLC12A6ENSG00000140199.7313.00240210.955800.569102.964801.65400K562SLBP
SLC12A6ENSG00000140199.7345.82960459.43270-0.409802.337901.68080K562SRSF1
SLC12A6ENSG00000140199.7431.40790317.397800.442703.043201.69020K562SSB
SLC12A6ENSG00000140199.7351.09560464.93900-0.405202.232501.59240K562TARDBP
SLC12A6ENSG00000140199.7600.11150469.645000.353602.821802.09610K562UPF1
SLC12A6ENSG00000140199.7553.34060401.858800.461403.370002.40770K562WDR3
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for SLC12A6 is not available on ENCORE database.





2 RBPs can affect the splicing of SLC12A6 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
A3SSSLC12A6ENSG00000140199.7chr15-3452738134527620345273813452751534528215345284000.103000.015880.07843longerK562AQR
A5SSSLC12A6ENSG00000140199.7chr15-3452959034529751345296193452975134528908345290160.080000.000740.07950longerHepG2FTO

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for SLC12A6 is not avaliable on ENCORE database.