SEC11A

General Information

Gene Name       : SEC11A
Gene ID             : ENSG00000140612.13
Essential Gene : No

Functions

Localization

Domains (AlphaFold: SEC11A)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878SEC11AENSG00000140612.13132.30104.13118.22ENCSR000AEF
HepG2SEC11AENSG00000140612.13110.89206.46158.68ENCSR985KAT
K562SEC11AENSG00000140612.13173.74171.15172.44ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for SEC11A is not avaliable on ENCORE database.



Proteins bound to RNA
  • SEC11A RNA is bound by 16 proteins.  







eCLIP assay for SEC11A is not avaliable on ENCORE database.





16 proteins are bound to SEC11A RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr158521317285213293-3'-UTR,CDS,intron-Distal,intron-Proximal3.156783.60227HepG2TIAL1
chr158521309685213116-3'-UTR,intron-Distal6.5513820.24221K562LIN28B
chr158521322985213269-3'-UTR,CDS,intron-Distal,intron-Proximal3.8169718.57871HepG2SUB1
chr158521305285213096-3'-UTR,intron-Distal,intron-Proximal3.657358.83307K562LIN28B
chr158521398385214013-3'-UTR,CDS,intron-Distal5.141447.03502HepG2SND1
chr158521304785213100-3'-UTR,intron-Distal,intron-Proximal5.0095346.50651HepG2SUB1
chr158521315485213229-3'-UTR,CDS,intron-Distal,intron-Proximal3.6169524.48327K562NOLC1
chr158521396185214012-3'-UTR,CDS,intron-Distal4.043445.16259K562LIN28B
chr158521304485213135-3'-UTR,intron-Distal,intron-Proximal4.259973.45012HepG2UPF1
chr158521305385213100-3'-UTR,intron-Distal,intron-Proximal3.071217.54411K562PABPC4
chr158521316085213214-3'-UTR,CDS,intron-Distal,intron-Proximal6.36911400.00000HepG2SUB1
chr158521283485212852-3'-UTR,intron-Distal3.369037.43930K562YBX3
chr158521311685213160-3'-UTR,intron-Distal,intron-Proximal3.9437415.19485K562LIN28B
chr158521311485213160-3'-UTR,intron-Distal,intron-Proximal5.9267186.72150HepG2SUB1
chr158521280785212841-3'-UTR,intron-Distal5.0553812.17370K562PABPC4
chr158521293785213023-3'-UTR,intron-Distal,intron-Proximal3.390193.91821K562APOBEC3C
chr158521281085212834-3'-UTR,intron-Distal3.605537.42315K562YBX3
chr158521311285213154-3'-UTR,intron-Distal,intron-Proximal4.4876120.32238K562NOLC1
chr158523485285234875-3'-UTR,CDS,intron-Distal3.8830610.06141K562TIA1
chr158521313385213216-3'-UTR,CDS,intron-Distal,intron-Proximal3.571078.88471HepG2LARP4
chr158525934585259352-5'-UTR,intron-Distal,intron-Proximal4.373945.20509K562YBX3
chr158525939885259493-5'-UTR,intron-Distal,intron-Proximal5.3239711.86516HepG2DDX3X
chr158525925485259261-5'-UTR,CDS,intron-Distal3.488869.85446K562TIA1
chr158525926185259292-5'-UTR,CDS,intron-Distal4.1613313.26803K562LIN28B
chr158525925385259261-5'-UTR,CDS,intron-Distal3.270165.10664K562LIN28B
chr158522396985224044-CDS,intron-Distal,intron-Proximal6.3887220.24221K562LIN28B
chr158522394185223967-CDS,intron-Distal,intron-Proximal5.206966.73605HepG2SND1
chr158523086785230922-CDS,intron-Distal3.254694.24433HepG2SND1
chr158523476585234793-CDS,intron-Distal,intron-Proximal3.319258.32372HepG2SUB1
chr158523097985231005-CDS,intron-Distal3.432165.71847HepG2SUB1
chr158523700185237145-intron-Distal4.9894314.28056HepG2QKI
chr158525917685259229-intron-Distal3.431903.87030HepG2RBM22
chr158523491485235011-intron-Distal,intron-Proximal3.393187.19702K562KHSRP
chr158522423285224308-intron-Distal3.803353.45805K562KHSRP
chr158524726485247344-intron-Distal3.663143.68481HepG2HNRNPM
chr158523509485235185-intron-Distal,intron-Proximal4.132514.72162K562KHSRP
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for SEC11A is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for SEC11A is not available on ENCORE database.

  • 104 RBPs can affect the levels of SEC11A.  








The Knockdown/knockout RNA-Seq assay for SEC11A is not available on ENCORE database.





104 RBPs can affect the gene expression of SEC11A :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
SEC11AENSG00000140612.91937.169601526.409000.343702.950101.84880HepG2AATF
SEC11AENSG00000140612.92729.824203749.65470-0.457903.697503.09450HepG2AKAP1
SEC11AENSG00000140612.92389.244203102.56230-0.376903.091802.26180HepG2ASCC1
SEC11AENSG00000140612.92304.379903085.57180-0.421208.669307.56750HepG2AUH
SEC11AENSG00000140612.92427.936001966.668900.303903.044702.23820HepG2CALR
SEC11AENSG00000140612.91143.257601824.83460-0.6746019.3840017.97540HepG2CKAP4
SEC11AENSG00000140612.91564.523402302.84590-0.557703.370202.51980HepG2CNOT7
SEC11AENSG00000140612.91203.848201635.84900-0.442403.930003.12410HepG2CPSF6
SEC11AENSG00000140612.91418.431501086.382700.384703.632302.41320HepG2CSTF2
SEC11AENSG00000140612.92621.090502967.67100-0.179202.186201.51560HepG2DAZAP1
SEC11AENSG00000140612.92034.663401684.603100.272302.048501.45460HepG2DDX21
SEC11AENSG00000140612.92193.097501648.090100.412104.793703.57900HepG2DDX24
SEC11AENSG00000140612.92686.914603591.96670-0.418803.650602.94190HepG2DDX3X
SEC11AENSG00000140612.92013.734603085.38260-0.615606.201205.30600HepG2DDX6
SEC11AENSG00000140612.91189.438701497.98130-0.332703.785602.97200HepG2DNAJC21
SEC11AENSG00000140612.91726.004402966.24280-0.7812010.892409.76350HepG2EIF2S1
SEC11AENSG00000140612.92165.852803278.13880-0.597905.831804.90550HepG2EIF4A3
SEC11AENSG00000140612.92626.350603542.59680-0.431709.505908.50060HepG2ETF1
SEC11AENSG00000140612.92493.834803307.22700-0.407303.559102.78070HepG2FXR1
SEC11AENSG00000140612.91907.045603068.08400-0.686008.012506.91190HepG2G3BP1
SEC11AENSG00000140612.9255.599301854.45520-2.8590070.9262068.28400HepG2GPKOW
SEC11AENSG00000140612.91413.874901849.44540-0.387406.023905.01970HepG2HNRNPF
SEC11AENSG00000140612.91759.713301419.714300.309602.838601.87580HepG2HNRNPM
SEC11AENSG00000140612.91393.400901821.17140-0.386304.489203.58570HepG2IGF2BP1
SEC11AENSG00000140612.92188.198503118.69230-0.511205.233004.33050HepG2IGF2BP2
SEC11AENSG00000140612.91924.215301706.934000.172802.155001.49910HepG2ILF2
SEC11AENSG00000140612.91385.760201668.50170-0.267903.727202.54470HepG2KIF1C
SEC11AENSG00000140612.91981.056503308.38040-0.739909.960608.73920HepG2MAGOH
SEC11AENSG00000140612.91992.041903326.94210-0.739908.894607.81600HepG2MATR3
SEC11AENSG00000140612.92371.322701665.396600.509706.824805.61030HepG2MSI2
SEC11AENSG00000140612.91832.113603405.34700-0.8943013.4935012.16080HepG2NCBP2
SEC11AENSG00000140612.91779.243103032.85220-0.7694010.333408.95920HepG2PABPC4
SEC11AENSG00000140612.92306.402402891.20280-0.326005.390704.58950HepG2PCBP1
SEC11AENSG00000140612.9771.49860994.01810-0.365603.238101.90580HepG2PKM
SEC11AENSG00000140612.91590.543201305.782500.284503.307302.46860HepG2PRPF4
SEC11AENSG00000140612.91896.386802941.93120-0.6335016.9218015.78950HepG2PTBP1
SEC11AENSG00000140612.91992.102402809.20830-0.495904.990404.21880HepG2PUF60
SEC11AENSG00000140612.92384.306502979.96110-0.321703.538402.78450HepG2PUM2
SEC11AENSG00000140612.91966.687403186.13240-0.6960016.3138014.97810HepG2QKI
SEC11AENSG00000140612.92052.510402891.63950-0.494506.983705.95220HepG2RBM25
SEC11AENSG00000140612.92259.673303274.06680-0.5350013.0725012.05550HepG2NELFE
SEC11AENSG00000140612.92527.100303049.38490-0.271003.985403.26290HepG2RECQL
SEC11AENSG00000140612.91509.801901992.37120-0.400103.967803.17400HepG2RPLP0
SEC11AENSG00000140612.9581.481501169.61750-1.0082017.9430016.58240HepG2RPS19
SEC11AENSG00000140612.91358.226201897.46440-0.482304.615903.59750HepG2RPS2
SEC11AENSG00000140612.91483.785902311.57710-0.639605.314004.20120HepG2RPS3A
SEC11AENSG00000140612.9958.454802415.46160-1.333505.044903.10090HepG2SF1
SEC11AENSG00000140612.92982.859101919.820700.635602.815002.13510HepG2SF3A3
SEC11AENSG00000140612.92691.748003062.88660-0.186302.129101.60020HepG2SF3B4
SEC11AENSG00000140612.9672.897901736.89890-1.3681019.5246017.00210HepG2SMNDC1
SEC11AENSG00000140612.92570.162203197.00830-0.314905.669105.05210HepG2SRSF1
SEC11AENSG00000140612.92400.050702773.81300-0.208802.254001.68210HepG2SRSF5
SEC11AENSG00000140612.91467.541901817.03410-0.308204.025703.21090HepG2SRSF7
SEC11AENSG00000140612.92287.312802600.95180-0.185402.163401.66310HepG2SRSF9
SEC11AENSG00000140612.92297.895402903.69700-0.337606.034505.33260HepG2SSB
SEC11AENSG00000140612.91329.874001721.13560-0.372101.950801.36860HepG2SUPV3L1
SEC11AENSG00000140612.92393.592002873.64500-0.263703.268102.66560HepG2TAF15
SEC11AENSG00000140612.9971.485701812.53660-0.899704.997903.59740HepG2TBRG4
SEC11AENSG00000140612.92235.291302640.43590-0.240302.081101.35330HepG2TIA1
SEC11AENSG00000140612.91001.946901623.78020-0.6966012.4674011.53810HepG2TIAL1
SEC11AENSG00000140612.92163.181102744.65330-0.343503.496502.50230HepG2TUFM
SEC11AENSG00000140612.91462.967501702.58340-0.218802.428001.76680HepG2UPF1
SEC11AENSG00000140612.92251.175701643.783500.453608.916307.94050HepG2UTP3
SEC11AENSG00000140612.91573.933002070.43920-0.395602.327301.32890HepG2XPO5
SEC11AENSG00000140612.94247.509403621.670000.229903.321802.71090K562AGGF1
SEC11AENSG00000140612.94566.422603768.480200.277002.430501.81780K562AKAP8L
SEC11AENSG00000140612.93371.829904962.02100-0.557407.945307.03680K562AQR
SEC11AENSG00000140612.95008.277503953.983200.340905.203503.90800K562ATP5C1
SEC11AENSG00000140612.92426.029602902.65690-0.258803.573302.47650K562BCLAF1
SEC11AENSG00000140612.9701.627501044.04530-0.573405.643703.99680K562CCAR1
SEC11AENSG00000140612.93296.015704103.87390-0.316304.075902.71610K562CPEB4
SEC11AENSG00000140612.92716.865304246.19530-0.6442019.7345018.14480K562DDX47
SEC11AENSG00000140612.95192.204504055.352500.356406.045404.67520K562DKC1
SEC11AENSG00000140612.91797.494102264.86190-0.333402.443101.58720K562EFTUD2
SEC11AENSG00000140612.9622.873001062.00990-0.769805.150903.73970K562EIF3A
SEC11AENSG00000140612.91894.890102425.29000-0.356002.220401.30350K562EIF3D
SEC11AENSG00000140612.92067.292402881.36270-0.479008.594507.19760K562EIF3G
SEC11AENSG00000140612.91805.328102671.33010-0.565307.656906.29240K562EIF4A3
SEC11AENSG00000140612.92184.657102778.07540-0.346705.096704.31030K562FXR1
SEC11AENSG00000140612.92463.422102976.07500-0.272703.203201.97440K562GLRX3
SEC11AENSG00000140612.9718.554602557.72050-1.8317057.0078053.31420K562GPKOW
SEC11AENSG00000140612.91618.062602294.86210-0.504106.697805.80940K562HNRNPC
SEC11AENSG00000140612.91677.021902049.30310-0.289202.432401.37480K562HNRNPF
SEC11AENSG00000140612.93287.063202435.640300.432403.732602.63910K562HNRNPM
SEC11AENSG00000140612.95867.936604014.445700.547607.713406.40440K562HSPD1
SEC11AENSG00000140612.94935.215303999.410000.303202.860802.01930K562KIF1C
SEC11AENSG00000140612.91599.038402183.85580-0.449703.015102.03550K562KRR1
SEC11AENSG00000140612.91622.308802222.24370-0.454005.128303.14510K562LARP7
SEC11AENSG00000140612.93111.278803920.22840-0.333403.486102.53740K562MAGOH
SEC11AENSG00000140612.93291.134703912.45320-0.249502.315301.47750K562MATR3
SEC11AENSG00000140612.95412.860504480.333900.272702.080701.30840K562MBNL1
SEC11AENSG00000140612.91696.075802496.60150-0.557807.884106.36640K562METAP2
SEC11AENSG00000140612.94229.355306192.24170-0.550008.004306.13140K562MSI2
SEC11AENSG00000140612.92523.779703128.96270-0.310105.396204.29060K562MTPAP
SEC11AENSG00000140612.94592.521303140.379900.548204.611503.38160K562NAA15
SEC11AENSG00000140612.92837.386503476.51430-0.293107.077305.96410K562NSUN2
SEC11AENSG00000140612.91447.721201777.23800-0.295902.660101.87670K562POLR2G
SEC11AENSG00000140612.91488.918402057.58100-0.466704.967203.70740K562PSIP1
SEC11AENSG00000140612.92762.894103808.66010-0.463106.805805.79960K562PTBP1
SEC11AENSG00000140612.95246.217606338.51560-0.272902.771101.95460K562PUF60
SEC11AENSG00000140612.95763.109306605.80660-0.196902.542901.62090K562PUM2
SEC11AENSG00000140612.95694.340003737.524400.607308.997608.06710K562PUS1
SEC11AENSG00000140612.94767.529603641.467100.388606.403105.52700K562RBM15
SEC11AENSG00000140612.92637.432203652.68880-0.469805.627404.37760K562RBM22
SEC11AENSG00000140612.92757.756203560.18590-0.368503.189701.66420K562RBM34
SEC11AENSG00000140612.91377.724801877.26040-0.446305.365803.97800K562RCC2
SEC11AENSG00000140612.92686.491203843.72130-0.516805.973004.28380K562NELFE
SEC11AENSG00000140612.91174.046102245.20910-0.9354012.3848010.63560K562RPS19
SEC11AENSG00000140612.91144.194801854.94180-0.697008.421006.56740K562RPS3
SEC11AENSG00000140612.92685.176003258.64670-0.279302.953102.06830K562SF3B4
SEC11AENSG00000140612.91271.304401779.59430-0.485205.110803.59190K562SRFBP1
SEC11AENSG00000140612.91672.063202200.51300-0.396203.453801.59280K562SRP68
SEC11AENSG00000140612.92823.780103514.62540-0.315706.610705.23360K562SRPK2
SEC11AENSG00000140612.91435.955001790.72680-0.318502.851201.77830K562SRSF4
SEC11AENSG00000140612.91308.224802134.31380-0.706207.897106.12510K562SUPV3L1
SEC11AENSG00000140612.92959.444003645.15480-0.300703.243902.34750K562TIA1
SEC11AENSG00000140612.91329.188901979.05070-0.574305.894104.47520K562TIAL1
SEC11AENSG00000140612.91481.442102102.46790-0.505105.933804.43090K562TRIM56
SEC11AENSG00000140612.91687.144302258.70780-0.420903.626602.44840K562UCHL5
SEC11AENSG00000140612.93087.967503686.22540-0.255504.015103.16410K562UPF1
SEC11AENSG00000140612.92332.394103280.02140-0.4919013.5322011.83530K562WDR43
SEC11AENSG00000140612.91723.830002299.67960-0.415803.524102.09970K562XRN2
SEC11AENSG00000140612.93632.512505589.50260-0.6218010.333608.54670K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for SEC11A is not available on ENCORE database.





25 RBPs can affect the splicing of SEC11A :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SESEC11AENSG00000140612.9chr15-8525796185258097852347658523487585259255852593940.069000.000000.00000includedK562SRSF1
SESEC11AENSG00000140612.9chr15-852139558521403085213252852133008522394385224063-0.055000.000000.00001excludedK562SF3B4
SESEC11AENSG00000140612.9chr15-8525796185258097852347658523487585259255852593940.054000.000000.00000includedK562PRPF8
SESEC11AENSG00000140612.9chr15-8525796185258097852347658523487585259255852593940.052000.001310.08859includedHepG2TBRG4
SESEC11AENSG00000140612.9chr15-852579618525809785234765852348758525925585259394-0.117000.000180.00328excludedHepG2U2AF2
SESEC11AENSG00000140612.9chr15-8525796185258097852347658523487585259255852593940.051000.000020.04313includedK562SDAD1
SESEC11AENSG00000140612.9chr15-852579618525809785234765852348758525925585259394-0.054000.000000.00020excludedHepG2SRSF7
SESEC11AENSG00000140612.9chr15-852308558523100585213955852140138525925585259294-0.251000.001520.02408excludedK562PUS1
SESEC11AENSG00000140612.9chr15-8525796185258097852347658523487585259255852593940.070000.000020.00464includedHepG2LARP4
SESEC11AENSG00000140612.9chr15-8525796185258097852347658523487585259255852593940.134000.000000.00000includedHepG2SRSF1
SESEC11AENSG00000140612.9chr15-8525796185258097852347658523487585259255852593940.062000.000000.00012includedHepG2IGF2BP3
SESEC11AENSG00000140612.9chr15-852139558521403085213252852133008522394385224063-0.057000.000000.00001excludedK562U2AF2
A3SSSEC11AENSG00000140612.9chr15-8521395585214154852139558521401385223943852240990.124000.000000.00000longerK562AQR
A3SSSEC11AENSG00000140612.9chr15-8523476585234932852347658523487585257961852580970.352000.000000.00000longerK562AQR
A3SSSEC11AENSG00000140612.9chr15-852139558521415485213955852140308522394385224099-0.578000.020360.09680shorterK562AQR
MXESEC11AENSG00000140612.9chr15-85213955852140138522394385224063852127748521330085230855852310050.122000.000090.029911includedK562KHDRBS1
MXESEC11AENSG00000140612.9chr15-85223943852240638523085585231005852139558521401385234765852348750.104000.000710.017431includedHepG2FTO
MXESEC11AENSG00000140612.9chr15-8522394385224063852347658523487585213955852140138525925585259358-0.121000.000030.002292includedK562RBM15
MXESEC11AENSG00000140612.9chr15-85223943852240638523085585231005852139558521401385234765852348750.079000.011600.097131includedK562DROSHA
MXESEC11AENSG00000140612.9chr15-85223943852240638523476585234875852139558521401385259255852593580.115000.000720.014631includedK562DROSHA
MXESEC11AENSG00000140612.9chr15-85213955852140138522394385224063852127748521330085230855852310050.123000.000040.037061includedK562ILF3
MXESEC11AENSG00000140612.9chr15-8522394385224063852347658523487585213955852140138525925585259358-0.099000.000240.056292includedK562UTP3
MXESEC11AENSG00000140612.9chr15-85213955852140138522394385224063852127748521330085230855852310050.078000.004130.048171includedK562U2AF2
MXESEC11AENSG00000140612.9chr15-85213955852140138522394385224063852127748521330085230855852310050.086000.003600.073971includedHepG2XRN2
MXESEC11AENSG00000140612.9chr15-85213955852140138522394385224063852127748521330085230855852310050.119000.000060.002621includedHepG2DDX55
MXESEC11AENSG00000140612.9chr15-85223943852240638523476585234875852139558521401385259255852593580.098000.001380.033111includedHepG2DDX55
MXESEC11AENSG00000140612.9chr15-85230855852310058523476585234875852139558521401385259255852592940.074000.001020.008301includedHepG2U2AF2
MXESEC11AENSG00000140612.9chr15-85223943852240638523476585234875852139558521401385259255852593580.107000.000140.040911includedK562PUM2
MXESEC11AENSG00000140612.9chr15-85223943852240638523476585234875852139558521401385259255852593580.100000.000350.036081includedK562PUM1
MXESEC11AENSG00000140612.9chr15-85213955852140138522394385224063852127748521330085230855852310050.148000.000010.002401includedK562RBFOX2
MXESEC11AENSG00000140612.9chr15-85213955852140138522394385224063852127748521330085230855852310050.176000.000000.000071includedK562DHX30
MXESEC11AENSG00000140612.9chr15-8523085585231005852347658523487585213955852140138525925585259294-0.053000.000680.017452includedK562PRPF8
MXESEC11AENSG00000140612.9chr15-85223943852240638523476585234875852139558521401385259255852593580.131000.000770.020081includedK562HNRNPUL1
MXESEC11AENSG00000140612.9chr15-85213955852140308522394385224063852127748521330085230855852310050.091000.001590.079621includedK562SERBP1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for SEC11A is not avaliable on ENCORE database.