PNPLA6

General Information

Gene Name       : PNPLA6
Gene ID             : ENSG00000032444.16
Essential Gene : No

Functions

Localization

Domains (AlphaFold: PNPLA6)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PNPLA6ENSG00000032444.165.9215.7610.84ENCSR000AEF
HepG2PNPLA6ENSG00000032444.1623.507.6415.57ENCSR985KAT
K562PNPLA6ENSG00000032444.169.226.677.95ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PNPLA6 is not avaliable on ENCORE database.



Proteins bound to RNA
  • PNPLA6 RNA is bound by 10 proteins.  







eCLIP assay for PNPLA6 is not avaliable on ENCORE database.





10 proteins are bound to PNPLA6 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr1976265217626603+3'-UTR4.041906.31568HepG2LARP4
chr1976003977600447+3'-UTR,5'-UTR,CDS4.114137.05872HepG2PPIG
chr1976048127604883+3'-UTR,CDS3.139986.00978HepG2PPIG
chr1976239247624013+CDS3.002153.90015HepG2PABPN1
chr1976221657622187+CDS,intron-Proximal3.159394.86350HepG2PRPF8
chr1976238377623862+CDS4.313734.08604HepG2PPIG
chr1976069487606997+CDS,intron-Distal,intron-Proximal3.009749.71086HepG2PRPF8
chr1976008197600866+5'-UTR,CDS3.488368.12996HepG2PPIG
chr1976064587606527+CDS3.636073.12746HepG2GRWD1
chr1976049327604944+3'-UTR,CDS4.173684.08604HepG2PPIG
chr1976004477600463+5'-UTR,CDS3.771414.80912HepG2PPIG
chr1976152807615305+CDS4.173684.08604HepG2PPIG
chr1976074047607468+CDS,intron-Proximal4.831155.65342K562AQR
chr1976074187607471+CDS,intron-Proximal3.240344.06762HepG2U2AF2
chr1976076577607730+CDS3.096536.47139HepG2PPIG
chr1976215397621576+CDS,intron-Proximal3.633354.84058HepG2LIN28B
chr1976259197625994+CDS3.174133.90015HepG2PABPN1
chr1976204927620624+CDS,intron-Proximal3.626904.47362HepG2G3BP1
chr1976154617615521+CDS3.570784.51003HepG2PPIG
chr1976261337626185+CDS5.245648.25598HepG2PPIG
chr1976214437621455+CDS3.488603.73238HepG2LIN28B
chr1976050357605065+CDS4.882007.06060HepG2PPIG
chr1976163717616434+intron-Distal,intron-Proximal4.119574.24431HepG2RBFOX2
chr1976221887622212+intron-Proximal4.126765.23469HepG2AQR
chr1976221877622241+intron-Proximal3.170615.68969HepG2PRPF8
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PNPLA6 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PNPLA6 is not available on ENCORE database.

  • 113 RBPs can affect the levels of PNPLA6.  








The Knockdown/knockout RNA-Seq assay for PNPLA6 is not available on ENCORE database.





113 RBPs can affect the gene expression of PNPLA6 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PNPLA6ENSG00000032444.111569.59940861.167600.8659025.3521023.93280HepG2ACO1
PNPLA6ENSG00000032444.112330.90240874.297201.414609.751908.81940HepG2AKAP1
PNPLA6ENSG00000032444.111215.19010723.284400.748402.694501.91950HepG2ASCC1
PNPLA6ENSG00000032444.112224.407501145.748000.9570012.4106011.14120HepG2AUH
PNPLA6ENSG00000032444.11815.34160629.573800.372902.561001.37790HepG2BUD13
PNPLA6ENSG00000032444.11321.32060449.31050-0.483702.365001.64780HepG2CALR
PNPLA6ENSG00000032444.112063.10960852.471001.2750018.5326016.20530HepG2CCAR1
PNPLA6ENSG00000032444.111045.34120860.989800.279802.991602.30570HepG2CKAP4
PNPLA6ENSG00000032444.11827.55400452.790600.869904.344203.38170HepG2CNOT7
PNPLA6ENSG00000032444.11993.50770691.999000.521704.279502.91860HepG2CPSF7
PNPLA6ENSG00000032444.11406.15450286.746200.502203.539002.38640HepG2YBX3
PNPLA6ENSG00000032444.11795.57690472.280700.7523011.7442010.59610HepG2CELF1
PNPLA6ENSG00000032444.112334.18370837.246201.4791014.2989012.98840HepG2DDX3X
PNPLA6ENSG00000032444.11538.73840945.06650-0.8108010.117207.86050HepG2DDX47
PNPLA6ENSG00000032444.11527.08910362.527000.539902.986801.57740HepG2DDX52
PNPLA6ENSG00000032444.112246.62330719.834301.641905.847204.97920HepG2DDX6
PNPLA6ENSG00000032444.11507.72800281.547800.850605.348204.39800HepG2DNAJC21
PNPLA6ENSG00000032444.11444.89950279.084100.672707.274006.28610HepG2DNAJC2
PNPLA6ENSG00000032444.11638.28640432.415400.561703.121502.14680HepG2EEF2
PNPLA6ENSG00000032444.111451.12600691.376401.069505.558604.73550HepG2EIF2S1
PNPLA6ENSG00000032444.11541.67790350.953800.626102.306101.47390HepG2EIF3D
PNPLA6ENSG00000032444.11369.62600538.24430-0.542203.219501.33700HepG2EIF3H
PNPLA6ENSG00000032444.11304.53090500.98200-0.718202.400601.61270HepG2EIF4G1
PNPLA6ENSG00000032444.11733.91750479.894600.612805.669304.52670HepG2EIF4G2
PNPLA6ENSG00000032444.11476.66820841.52290-0.8200010.903709.27660HepG2EWSR1
PNPLA6ENSG00000032444.11581.58890313.806300.8900010.339208.07960HepG2FAM120A
PNPLA6ENSG00000032444.111384.97620848.563900.706706.737905.59120HepG2FIP1L1
PNPLA6ENSG00000032444.11283.90790631.92900-1.1543015.9065014.09380HepG2FUBP3
PNPLA6ENSG00000032444.111504.38370771.499300.963304.742203.85290HepG2FXR1
PNPLA6ENSG00000032444.111121.44380715.203100.648801.978101.41180HepG2G3BP1
PNPLA6ENSG00000032444.11521.04840312.457900.737705.619704.33770HepG2GEMIN5
PNPLA6ENSG00000032444.11726.85840359.139201.017006.934005.30610HepG2GNB2L1
PNPLA6ENSG00000032444.11728.87270419.276200.797703.881802.56330HepG2GRSF1
PNPLA6ENSG00000032444.11745.71130383.540200.959103.199801.73170HepG2HNRNPA0
PNPLA6ENSG00000032444.11422.52480284.245300.571802.433101.82480HepG2HNRNPA1
PNPLA6ENSG00000032444.11760.92640374.463301.022804.681302.84440HepG2HNRNPAB
PNPLA6ENSG00000032444.11543.26440316.177900.780804.839803.94120HepG2HNRNPC
PNPLA6ENSG00000032444.11847.33280577.129700.553907.429706.32740HepG2HNRNPF
PNPLA6ENSG00000032444.111559.68650725.318501.104506.853305.79300HepG2HNRNPK
PNPLA6ENSG00000032444.111018.15690462.472401.1384032.1010030.11040HepG2HNRNPL
PNPLA6ENSG00000032444.11791.97160314.086901.334209.874608.78570HepG2HNRNPU
PNPLA6ENSG00000032444.11724.20920568.310300.349602.734302.01490HepG2IGF2BP1
PNPLA6ENSG00000032444.111368.90630726.819100.913304.396303.56210HepG2IGF2BP2
PNPLA6ENSG00000032444.111312.40150901.056000.542402.178201.44890HepG2LARP4
PNPLA6ENSG00000032444.111778.09690794.103401.162808.116307.05790HepG2NCBP2
PNPLA6ENSG00000032444.11469.79110789.04180-0.748103.026501.52770HepG2NKRF
PNPLA6ENSG00000032444.111057.93020503.465501.071205.590604.51300HepG2NOL12
PNPLA6ENSG00000032444.11409.84540266.570100.620502.857501.38220HepG2NOLC1
PNPLA6ENSG00000032444.111124.31100383.159801.5529010.508108.31380HepG2NONO
PNPLA6ENSG00000032444.11707.39310414.058500.772603.678102.64330HepG2PABPC1
PNPLA6ENSG00000032444.11444.63170310.882900.516102.670301.83510HepG2PARN
PNPLA6ENSG00000032444.11960.93700752.224000.353202.856902.24360HepG2PCBP1
PNPLA6ENSG00000032444.11553.44420280.139100.9822013.7746012.20760HepG2PPIL4
PNPLA6ENSG00000032444.111159.45790480.627201.2704026.5827024.99200HepG2PUF60
PNPLA6ENSG00000032444.11916.66770510.236500.8451019.2256017.94750HepG2PUM1
PNPLA6ENSG00000032444.11505.53020828.95870-0.713509.077408.04490HepG2QKI
PNPLA6ENSG00000032444.11920.874001099.56000-0.255902.191101.71550HepG2RBM22
PNPLA6ENSG00000032444.11718.50350424.552100.759003.283402.19670HepG2RBM27
PNPLA6ENSG00000032444.11562.04290344.758400.705002.697701.65330HepG2RCC2
PNPLA6ENSG00000032444.111268.22490851.836200.574109.102508.22420HepG2NELFE
PNPLA6ENSG00000032444.11541.51020341.564300.664704.546103.77930HepG2RPS19
PNPLA6ENSG00000032444.11593.31600279.703901.0848018.7638017.30690HepG2SAFB2
PNPLA6ENSG00000032444.111636.31320996.695700.715105.936204.92460HepG2SF3A3
PNPLA6ENSG00000032444.11309.63190561.14250-0.857808.057606.91270HepG2SF3B1
PNPLA6ENSG00000032444.11750.49190345.664401.118403.309201.69740HepG2SFPQ
PNPLA6ENSG00000032444.11642.26990460.907200.478605.505604.57300HepG2SLBP
PNPLA6ENSG00000032444.11606.15440326.174600.8939014.2434012.96110HepG2SMN1
PNPLA6ENSG00000032444.11906.56690403.892201.166304.541203.29020HepG2SMNDC1
PNPLA6ENSG00000032444.111493.809601241.872100.266402.568002.07850HepG2SRFBP1
PNPLA6ENSG00000032444.11430.60010831.78760-0.9499017.0102016.04860HepG2SRSF1
PNPLA6ENSG00000032444.11771.02390474.584800.7000010.681409.55910HepG2SRSF5
PNPLA6ENSG00000032444.111404.922401078.168500.381804.271003.66310HepG2SSB
PNPLA6ENSG00000032444.11986.67680396.285601.3159014.3593011.71420HepG2STIP1
PNPLA6ENSG00000032444.11912.13010539.703300.7570014.7076013.45620HepG2SUCLG1
PNPLA6ENSG00000032444.11339.51850747.65430-1.1389019.7365018.43350HepG2TAF15
PNPLA6ENSG00000032444.11544.45410277.937800.969902.660101.68030HepG2TFIP11
PNPLA6ENSG00000032444.11617.82130305.166101.017506.007005.32330HepG2TIAL1
PNPLA6ENSG00000032444.111052.14240307.924201.7726062.0462059.85550HepG2TRIM56
PNPLA6ENSG00000032444.11814.20840469.600700.793903.176502.23510HepG2TUFM
PNPLA6ENSG00000032444.11991.50060369.819301.422705.446304.02220HepG2U2AF2
PNPLA6ENSG00000032444.11854.19180497.096700.780902.874002.02300HepG2UBE2L3
PNPLA6ENSG00000032444.11448.16400244.938200.871502.229301.54780HepG2UCHL5
PNPLA6ENSG00000032444.111394.93760883.917800.6581014.2521012.90050HepG2UPF1
PNPLA6ENSG00000032444.11489.89310342.048200.518203.295901.94490K562ABCF1
PNPLA6ENSG00000032444.11739.65540562.464600.395003.699603.06110K562AGGF1
PNPLA6ENSG00000032444.11567.72470432.177500.393503.243801.58980K562AKAP1
PNPLA6ENSG00000032444.11482.55560630.08400-0.384801.940501.43300K562AQR
PNPLA6ENSG00000032444.11781.06280614.094400.346902.921901.98480K562ATP5C1
PNPLA6ENSG00000032444.11506.41730231.089701.1318015.0483012.77470K562BCLAF1
PNPLA6ENSG00000032444.11236.16230138.129800.773703.742502.72580K562BOP1
PNPLA6ENSG00000032444.11348.07220233.252300.577403.450802.24480K562CCAR1
PNPLA6ENSG00000032444.11565.62960354.549100.673803.487701.84060K562CKAP4
PNPLA6ENSG00000032444.11265.96740146.861200.856705.417804.32830K562CPSF6
PNPLA6ENSG00000032444.11427.52840175.316101.2860014.9561012.27260K562CSTF2
PNPLA6ENSG00000032444.11792.93450437.922500.8564011.839109.50940K562DDX3X
PNPLA6ENSG00000032444.11635.64440481.042900.402003.665002.25310K562EIF2S1
PNPLA6ENSG00000032444.11583.36000382.209600.609906.147805.13900K562EIF2S2
PNPLA6ENSG00000032444.11509.77700305.027400.740807.076105.01050K562EXOSC5
PNPLA6ENSG00000032444.11343.31800245.937100.481202.627001.80150K562FIP1L1
PNPLA6ENSG00000032444.11250.38960149.447900.744403.867902.85100K562FMR1
PNPLA6ENSG00000032444.11244.51950126.679400.948705.561504.21310K562FTO
PNPLA6ENSG00000032444.1122.0776082.16820-1.896006.577305.38350K562G3BP2
PNPLA6ENSG00000032444.11285.12050140.207901.023907.175605.89670K562GPKOW
PNPLA6ENSG00000032444.11697.15310509.274800.452903.112602.31280K562GRSF1
PNPLA6ENSG00000032444.11381.91310244.717800.642002.904002.29500K562HNRNPC
PNPLA6ENSG00000032444.11554.78280212.530201.384204.340302.93540K562IGF2BP2
PNPLA6ENSG00000032444.11332.95570218.356500.608503.658701.83510K562LSM11
PNPLA6ENSG00000032444.11364.31270223.122200.707203.716502.73210K562MAGOH
PNPLA6ENSG00000032444.11272.57550136.862100.993806.788905.38320K562METAP2
PNPLA6ENSG00000032444.11398.28640192.601601.048104.205002.52450K562NONO
PNPLA6ENSG00000032444.11743.31270554.212200.423404.819103.87260K562NSUN2
PNPLA6ENSG00000032444.11402.93480279.235300.529003.304902.39410K562PPIG
PNPLA6ENSG00000032444.11408.62840216.795000.914409.171908.00990K562PTBP1
PNPLA6ENSG00000032444.11551.92700737.38100-0.417902.830401.74960K562PUM1
PNPLA6ENSG00000032444.11816.03820580.416100.491404.008403.37270K562PUS1
PNPLA6ENSG00000032444.11134.3348085.339500.654402.420901.62350K562SF3B4
PNPLA6ENSG00000032444.11269.20170189.859500.503702.204601.31000K562SRFBP1
PNPLA6ENSG00000032444.11393.19770189.717201.051305.124202.82820K562SRP68
PNPLA6ENSG00000032444.11312.02160192.639100.695603.241902.08470K562SRSF4
PNPLA6ENSG00000032444.11368.46300200.811500.875607.127405.32800K562SRSF5
PNPLA6ENSG00000032444.11385.97770183.599801.071902.891201.85130K562SUPV3L1
PNPLA6ENSG00000032444.11482.53290215.065001.165804.049503.18740K562TARDBP
PNPLA6ENSG00000032444.11511.62250207.469701.3021017.8374015.60950K562TIA1
PNPLA6ENSG00000032444.11374.83410203.726200.879504.694503.19960K562TRA2A
PNPLA6ENSG00000032444.11420.80320224.305000.907604.006502.82500K562TRIM56
PNPLA6ENSG00000032444.11348.40890194.420100.841502.565801.59080K562UCHL5
PNPLA6ENSG00000032444.11359.08190522.90230-0.542205.454304.30640K562WDR43
PNPLA6ENSG00000032444.11475.23470198.135301.262106.559104.44850K562XRN2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PNPLA6 is not available on ENCORE database.





6 RBPs can affect the splicing of PNPLA6 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPNPLA6ENSG00000032444.11chr19+760686976069537606407760657076074467607556-0.243000.000040.00249excludedK562AKAP8L
SEPNPLA6ENSG00000032444.11chr19+760686976069537606407760657076074467607556-0.196000.001610.02521excludedK562PUS1
SEPNPLA6ENSG00000032444.11chr19+759926475993327599038759912575996357599788-0.295000.000090.01046excludedHepG2FTO
SEPNPLA6ENSG00000032444.11chr19+759926475993327599038759912575996357599788-0.251000.000210.02980excludedHepG2LARP4
SEPNPLA6ENSG00000032444.11chr19+759926475993327599038759912575996357599788-0.597000.000010.00134excludedHepG2PCBP1
SEPNPLA6ENSG00000032444.11chr19+760686976069537606407760657076074467607556-0.198000.000710.02115excludedK562AGGF1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PNPLA6 is not avaliable on ENCORE database.