PLEKHG2

General Information

Gene Name       : PLEKHG2
Gene ID             : ENSG00000090924.14
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: PLEKHG2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PLEKHG2ENSG00000090924.1472.1311.6241.88ENCSR000AEF
HepG2PLEKHG2ENSG00000090924.1412.504.168.33ENCSR985KAT
K562PLEKHG2ENSG00000090924.1413.4318.6216.02ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PLEKHG2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • PLEKHG2 RNA is bound by 14 proteins.  







eCLIP assay for PLEKHG2 is not avaliable on ENCORE database.





14 proteins are bound to PLEKHG2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr193991662939916804+3'-UTR3.029883.60923HepG2HNRNPL
chr193990832839908368+CDS,intron-Proximal4.401033.59236HepG2AQR
chr193990742939907513+CDS,intron-Proximal4.281984.24670HepG2SF3B4
chr193990713839907198+CDS,intron-Proximal3.100693.57857HepG2SF3B4
chr193990839539908606+CDS,intron-Distal,intron-Proximal4.1513410.30373HepG2EFTUD2
chr193990722539907275+CDS,intron-Proximal3.683716.65114HepG2PRPF8
chr193990963939909698+CDS,intron-Proximal4.831153.62536K562AQR
chr193990713039907241+CDS,intron-Proximal4.133983.18234K562BUD13
chr193990599439906091+CDS,intron-Proximal4.167215.52342HepG2PPIG
chr193991188539911948+CDS,intron-Proximal3.579273.09957HepG2AQR
chr193990719139907244+CDS,intron-Proximal4.758644.67689HepG2PPIG
chr193990483539904910+CDS,intron-Proximal5.085046.22530K562AQR
chr193991144439911493+CDS,intron-Proximal4.316383.20743HepG2PPIG
chr193990483239904925+CDS,intron-Proximal5.043369.65239HepG2EFTUD2
chr193990937039909455+CDS,intron-Proximal5.174486.16445HepG2PPIG
chr193990963139909691+CDS,intron-Proximal3.733125.13777HepG2PRPF8
chr193990562939905690+CDS,intron-Distal,intron-Proximal4.523903.49905HepG2PPIG
chr193991487239914905+CDS,intron-Distal3.849623.15006K562RBM15
chr193990698439907056+CDS,intron-Proximal4.178494.96634HepG2PPIG
chr193990748639907549+CDS,intron-Proximal3.616743.86355HepG2PPIG
chr193991188439912029+CDS,intron-Proximal4.597569.64986K562PRPF8
chr193991187739911981+CDS,intron-Proximal5.590319.23760K562AQR
chr193990846939908547+CDS,intron-Proximal3.552154.44431K562BUD13
chr193990830239908370+CDS,intron-Proximal3.300773.67792HepG2PRPF8
chr193990746639907515+CDS,intron-Proximal3.812114.49024K562AQR
chr193990839639908500+intron-Distal,intron-Proximal4.390083.71802K562RBFOX2
chr193990839339908529+intron-Distal,intron-Proximal4.222363.84437HepG2PRPF4
chr193990839839908469+intron-Distal,intron-Proximal3.619195.03105K562BUD13
chr193990844139908538+intron-Distal,intron-Proximal5.3673721.77316K562AQR
chr193990634639906405+intron-Distal5.317064.83371K562EFTUD2
chr193990735139907461+intron-Distal,intron-Proximal3.812894.02963HepG2DDX59
chr193990728739907465+intron-Distal,intron-Proximal4.917584.86763HepG2PCBP2
chr193990839239908467+intron-Distal,intron-Proximal6.1514610.20324K562DDX24
chr193990738039907470+intron-Distal,intron-Proximal4.810646.13079HepG2HNRNPK
chr193990837839908541+intron-Distal,intron-Proximal5.7537612.95646HepG2AQR
chr193990838939908475+intron-Distal,intron-Proximal5.183718.72621HepG2PRPF8
chr193990846939908541+intron-Proximal5.370766.53290K562DDX24
chr193990847639908536+intron-Proximal4.170716.81564HepG2PRPF8
chr193990713839907189+intron-Proximal4.641797.21143HepG2EFTUD2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PLEKHG2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PLEKHG2 is not available on ENCORE database.

  • 121 RBPs can affect the levels of PLEKHG2.  








The Knockdown/knockout RNA-Seq assay for PLEKHG2 is not available on ENCORE database.





121 RBPs can affect the gene expression of PLEKHG2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PLEKHG2ENSG00000090924.10935.450601231.56060-0.396802.727601.79100HepG2ABCF1
PLEKHG2ENSG00000090924.10909.74460756.703300.265602.408301.83420HepG2ACO1
PLEKHG2ENSG00000090924.101400.953701033.778700.438403.120202.01630HepG2AKAP8
PLEKHG2ENSG00000090924.101409.74450726.087500.9571015.3546013.96730HepG2AUH
PLEKHG2ENSG00000090924.101669.596201298.818300.362203.146602.51270HepG2BOP1
PLEKHG2ENSG00000090924.101289.53340922.609400.483004.850203.24110HepG2BUD13
PLEKHG2ENSG00000090924.101508.529301192.405100.339202.663901.98720HepG2CPSF6
PLEKHG2ENSG00000090924.101351.904701014.086900.414703.822602.52750HepG2CPSF7
PLEKHG2ENSG00000090924.10931.87140646.035500.528406.303605.40880HepG2CELF1
PLEKHG2ENSG00000090924.10963.50030694.768900.471706.302005.25000HepG2DAZAP1
PLEKHG2ENSG00000090924.10545.32850699.81930-0.359903.626402.68940HepG2DDX19B
PLEKHG2ENSG00000090924.10347.01200517.15630-0.575604.483803.31030HepG2DDX24
PLEKHG2ENSG00000090924.10602.37090449.105900.423502.289801.71590HepG2DDX3X
PLEKHG2ENSG00000090924.101076.22750430.002701.3235010.405909.02130HepG2DDX55
PLEKHG2ENSG00000090924.102173.187801354.057300.682404.064702.89240HepG2DDX59
PLEKHG2ENSG00000090924.10677.60160385.922600.812006.523705.60620HepG2DDX6
PLEKHG2ENSG00000090924.10485.00640723.94710-0.577906.787905.81670HepG2DKC1
PLEKHG2ENSG00000090924.101000.32070576.516800.7949012.1697010.77910HepG2DNAJC21
PLEKHG2ENSG00000090924.10709.85650571.512300.312602.915602.24910HepG2DNAJC2
PLEKHG2ENSG00000090924.10726.38320370.866400.9697010.063008.97300HepG2EIF2S1
PLEKHG2ENSG00000090924.10775.69950567.105200.451802.991402.05630HepG2EIF3D
PLEKHG2ENSG00000090924.10550.10470409.788000.424702.105901.54580HepG2EIF4A3
PLEKHG2ENSG00000090924.10977.77810399.106401.2926014.0258012.54350HepG2EIF4B
PLEKHG2ENSG00000090924.101234.25550833.623700.566108.880707.90600HepG2ETF1
PLEKHG2ENSG00000090924.101802.580601243.553200.535504.371003.42000HepG2FIP1L1
PLEKHG2ENSG00000090924.10753.26850413.649700.864707.508006.40950HepG2FXR1
PLEKHG2ENSG00000090924.10896.30680383.620401.2242016.3102014.75970HepG2G3BP1
PLEKHG2ENSG00000090924.10578.82900407.393300.506603.128002.18130HepG2G3BP2
PLEKHG2ENSG00000090924.10793.20280495.735300.678005.843304.34770HepG2GNB2L1
PLEKHG2ENSG00000090924.10943.834001351.73650-0.518204.100503.33380HepG2GPKOW
PLEKHG2ENSG00000090924.10832.32970638.453600.382503.334902.32070HepG2HNRNPA2B1
PLEKHG2ENSG00000090924.10952.91170647.441600.557503.622202.83670HepG2HNRNPC
PLEKHG2ENSG00000090924.10619.51580388.684700.672405.400904.44910HepG2HNRNPK
PLEKHG2ENSG00000090924.101114.41310857.922400.377303.161402.14970HepG2HNRNPM
PLEKHG2ENSG00000090924.10981.10000643.159000.609106.693905.78860HepG2HNRNPU
PLEKHG2ENSG00000090924.10782.699701009.16180-0.366603.379102.58580HepG2IGF2BP1
PLEKHG2ENSG00000090924.10711.23940389.906000.867108.447107.33550HepG2IGF2BP2
PLEKHG2ENSG00000090924.10620.78430366.053700.761902.700401.72870HepG2IGF2BP3
PLEKHG2ENSG00000090924.10835.91960656.960700.347503.971003.10830HepG2ILF2
PLEKHG2ENSG00000090924.10622.45770392.245600.666104.100202.85920HepG2KHSRP
PLEKHG2ENSG00000090924.10910.64790593.506200.617502.762801.71210HepG2METAP2
PLEKHG2ENSG00000090924.101496.374701006.330000.572306.987805.76010HepG2MSI2
PLEKHG2ENSG00000090924.10668.96280425.855600.651504.823704.00060HepG2NCBP2
PLEKHG2ENSG00000090924.10849.551901143.77800-0.429003.487802.64630HepG2NSUN2
PLEKHG2ENSG00000090924.10563.67950379.136300.572103.751402.91940HepG2PABPC4
PLEKHG2ENSG00000090924.10865.50220636.581500.443104.417903.37730HepG2PARN
PLEKHG2ENSG00000090924.10619.42180417.620600.568606.045005.20300HepG2PCBP1
PLEKHG2ENSG00000090924.10194.70090352.57860-0.856704.399802.49550HepG2PNPT1
PLEKHG2ENSG00000090924.10707.10060424.935400.7346010.174409.25320HepG2PTBP1
PLEKHG2ENSG00000090924.10844.56480698.037200.274802.325101.77210HepG2PUM1
PLEKHG2ENSG00000090924.10861.17210697.552000.303901.970801.39850HepG2PUM2
PLEKHG2ENSG00000090924.10509.50510770.74410-0.597208.412607.43780HepG2PUS1
PLEKHG2ENSG00000090924.10691.83150460.235100.587905.743504.89160HepG2QKI
PLEKHG2ENSG00000090924.101385.40700696.759700.9915014.9826013.97330HepG2RBM22
PLEKHG2ENSG00000090924.10892.92140417.685501.0960017.9092016.29090HepG2RBM25
PLEKHG2ENSG00000090924.10840.82230472.919900.8301012.9077011.89840HepG2NELFE
PLEKHG2ENSG00000090924.10711.65940440.446800.692108.780207.77430HepG2RECQL
PLEKHG2ENSG00000090924.10776.963501104.03080-0.506904.988404.10720HepG2RPLP0
PLEKHG2ENSG00000090924.10837.34770551.848700.601506.197005.31850HepG2RPS19
PLEKHG2ENSG00000090924.10584.70330394.777400.566603.147602.29560HepG2RPS3A
PLEKHG2ENSG00000090924.10724.023601327.12090-0.874209.063307.78830HepG2SF3A3
PLEKHG2ENSG00000090924.10900.847301276.85790-0.503204.734203.83250HepG2SF3B1
PLEKHG2ENSG00000090924.10753.84440442.429100.7687010.801109.75110HepG2SF3B4
PLEKHG2ENSG00000090924.101253.43730520.836101.266904.246002.38090HepG2SFPQ
PLEKHG2ENSG00000090924.101063.06090667.888600.6704013.8073012.54050HepG2SMN1
PLEKHG2ENSG00000090924.101221.46180479.640401.348505.675503.62000HepG2SNRNP200
PLEKHG2ENSG00000090924.10975.36310786.972500.309503.020602.50430HepG2SRFBP1
PLEKHG2ENSG00000090924.10337.97430461.79340-0.450303.264702.76190HepG2SRSF1
PLEKHG2ENSG00000090924.10965.693301373.81750-0.508603.395302.27500HepG2SRSF3
PLEKHG2ENSG00000090924.101076.87280649.241700.7299012.9417011.72180HepG2SRSF5
PLEKHG2ENSG00000090924.10818.842501006.86990-0.298202.952502.23690HepG2SRSF7
PLEKHG2ENSG00000090924.10752.13290375.687801.0014019.4561018.23630HepG2SRSF9
PLEKHG2ENSG00000090924.10345.95180683.29260-0.9819016.6456015.60830HepG2SSB
PLEKHG2ENSG00000090924.101211.49620738.407400.7142012.6671011.50110HepG2SUCLG1
PLEKHG2ENSG00000090924.10318.56080415.05920-0.381702.200701.69070HepG2TAF15
PLEKHG2ENSG00000090924.10507.84920381.402800.413002.669601.84660HepG2TIA1
PLEKHG2ENSG00000090924.10798.53170624.841700.353802.219101.76120HepG2TIAL1
PLEKHG2ENSG00000090924.10882.00630630.542700.484106.105605.32530HepG2TRIM56
PLEKHG2ENSG00000090924.101822.06520558.074601.706907.959106.20150HepG2U2AF2
PLEKHG2ENSG00000090924.101203.36460679.914500.823508.268606.78990HepG2UBE2L3
PLEKHG2ENSG00000090924.101501.241901176.953500.351004.937004.04560HepG2UPF1
PLEKHG2ENSG00000090924.10675.696001136.30210-0.7499014.3104013.10970HepG2UTP3
PLEKHG2ENSG00000090924.10949.697301294.42330-0.446807.882407.08090HepG2ZNF622
PLEKHG2ENSG00000090924.101203.966301530.94460-0.346602.637901.45240K562ABCF1
PLEKHG2ENSG00000090924.10348.31800929.23530-1.4156016.7984015.52420K562AGGF1
PLEKHG2ENSG00000090924.10607.170001020.96250-0.749808.275506.33520K562AKAP8
PLEKHG2ENSG00000090924.10430.67430966.88030-1.1667013.4933011.88830K562AKAP8L
PLEKHG2ENSG00000090924.10565.53830975.72430-0.786804.496203.78160K562AQR
PLEKHG2ENSG00000090924.10550.611801014.43140-0.881606.900005.36430K562ATP5C1
PLEKHG2ENSG00000090924.10782.419801223.19670-0.644606.713605.33600K562BOP1
PLEKHG2ENSG00000090924.10981.87720725.490000.436503.442802.23970K562CCAR1
PLEKHG2ENSG00000090924.10981.391201300.60480-0.406304.231003.25920K562CPSF6
PLEKHG2ENSG00000090924.10981.839501609.47430-0.713009.028307.30870K562CELF1
PLEKHG2ENSG00000090924.10692.78670950.00920-0.455505.013803.34830K562DDX21
PLEKHG2ENSG00000090924.101236.825101526.00690-0.303101.866401.31150K562DDX47
PLEKHG2ENSG00000090924.10538.493101040.62780-0.9505010.180808.28700K562DKC1
PLEKHG2ENSG00000090924.10589.25560454.214100.375402.117001.31730K562EFTUD2
PLEKHG2ENSG00000090924.101367.11960854.602200.6777011.8890010.55170K562EIF2S2
PLEKHG2ENSG00000090924.10398.93050268.644700.570303.936402.99470K562EIF3G
PLEKHG2ENSG00000090924.10594.29070290.708601.031504.528403.78140K562FXR1
PLEKHG2ENSG00000090924.1079.24580162.87740-1.039404.561803.60380K562G3BP2
PLEKHG2ENSG00000090924.10910.222901158.49990-0.348003.528702.24230K562GLRX3
PLEKHG2ENSG00000090924.10838.462801241.75400-0.566606.180004.99540K562GPKOW
PLEKHG2ENSG00000090924.10730.191601138.68510-0.641004.803703.80910K562GRSF1
PLEKHG2ENSG00000090924.10433.88320750.09230-0.789803.651702.18490K562HNRNPA2B1
PLEKHG2ENSG00000090924.101070.91850633.744500.756809.801608.73270K562HNRNPC
PLEKHG2ENSG00000090924.10888.79470565.783700.651507.364805.43570K562HNRNPF
PLEKHG2ENSG00000090924.10983.662101378.97890-0.487403.982202.68750K562HNRNPL
PLEKHG2ENSG00000090924.10343.867201026.21090-1.577408.254106.63210K562KIF1C
PLEKHG2ENSG00000090924.10663.061301060.31210-0.677305.094603.77770K562KRR1
PLEKHG2ENSG00000090924.10545.01130982.24780-0.849804.942903.37410K562MAK16
PLEKHG2ENSG00000090924.10507.05570287.010300.820903.495502.44200K562MATR3
PLEKHG2ENSG00000090924.10845.654001217.99970-0.526408.448907.10940K562MTPAP
PLEKHG2ENSG00000090924.10289.33550805.77680-1.4776017.2844014.52750K562NAA15
PLEKHG2ENSG00000090924.10789.102001353.37400-0.7783021.0873019.30980K562NSUN2
PLEKHG2ENSG00000090924.10277.54690656.17400-1.241307.521205.61630K562PABPN1
PLEKHG2ENSG00000090924.101008.28110618.615300.704708.785706.18620K562PHF6
PLEKHG2ENSG00000090924.10993.595301249.07220-0.330102.099901.38910K562PPIG
PLEKHG2ENSG00000090924.10883.58010568.176400.636903.224902.23560K562PSIP1
PLEKHG2ENSG00000090924.10647.78660279.520201.212503.609402.86260K562PTBP1
PLEKHG2ENSG00000090924.101072.148701519.15600-0.502804.318602.96180K562PUM1
PLEKHG2ENSG00000090924.101719.359401488.837400.207602.193301.33700K562PUM2
PLEKHG2ENSG00000090924.10295.68400959.10290-1.6976016.6026015.31150K562PUS1
PLEKHG2ENSG00000090924.10299.87800934.31650-1.6395021.7534020.02620K562RBM15
PLEKHG2ENSG00000090924.10503.72730267.769200.911604.542603.43440K562RBM22
PLEKHG2ENSG00000090924.10475.53180261.220800.864203.256801.71190K562RBM34
PLEKHG2ENSG00000090924.10813.90560518.185000.651307.303305.68450K562RCC2
PLEKHG2ENSG00000090924.10564.09890281.844401.000902.690301.61410K562NELFE
PLEKHG2ENSG00000090924.10536.95410273.224200.974605.039503.63240K562RPS3
PLEKHG2ENSG00000090924.10324.98700600.12000-0.884903.805002.32830K562SF1
PLEKHG2ENSG00000090924.101017.700201335.33510-0.391903.340802.44840K562SF3A3
PLEKHG2ENSG00000090924.10262.12160169.301000.630503.707602.71420K562SF3B4
PLEKHG2ENSG00000090924.10547.09070799.04660-0.546504.679902.99910K562SLBP
PLEKHG2ENSG00000090924.10311.84440689.15120-1.144006.150404.08350K562SNRNP200
PLEKHG2ENSG00000090924.10784.44950491.246500.675106.113104.42250K562SRFBP1
PLEKHG2ENSG00000090924.10376.16260263.710400.512302.748501.70310K562SRSF4
PLEKHG2ENSG00000090924.10612.92370847.75480-0.467905.051303.45380K562SRSF7
PLEKHG2ENSG00000090924.101087.810201443.86490-0.408503.144001.68160K562SSRP1
PLEKHG2ENSG00000090924.10818.364501320.65690-0.690406.037504.11430K562STAU1
PLEKHG2ENSG00000090924.10439.67870824.36660-0.906804.366202.40880K562SUPT6H
PLEKHG2ENSG00000090924.10587.93330277.268801.084307.005605.83010K562TARDBP
PLEKHG2ENSG00000090924.101974.096701610.386700.293703.033301.55850K562UBE2L3
PLEKHG2ENSG00000090924.10637.34220972.20490-0.609202.955901.60530K562UTP18
PLEKHG2ENSG00000090924.10755.897901227.89780-0.699906.611205.22460K562WDR3
PLEKHG2ENSG00000090924.10710.022601099.36860-0.630703.297802.34630K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PLEKHG2 is not available on ENCORE database.





2 RBPs can affect the splicing of PLEKHG2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
RIPLEKHG2ENSG00000090924.10chr19+3991124339911492399112433991129939911390399114920.361000.001710.02074includedHepG2SF3A3
MXEPLEKHG2ENSG00000090924.10chr19+39911588399116363991171439911753399113903991149239911922399119390.478000.001210.017611includedHepG2SFPQ

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PLEKHG2 is not avaliable on ENCORE database.