PKMYT1

General Information

Gene Name       : PKMYT1
Gene ID             : ENSG00000127564.16
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: PKMYT1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PKMYT1ENSG00000127564.164.358.926.63ENCSR000AEF
HepG2PKMYT1ENSG00000127564.1624.409.1516.77ENCSR985KAT
K562PKMYT1ENSG00000127564.1672.3430.7051.52ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PKMYT1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • PKMYT1 RNA is bound by 16 proteins.  







eCLIP assay for PKMYT1 is not avaliable on ENCORE database.





16 proteins are bound to PKMYT1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr1630231393023213-3'-UTR,CDS,intron-Distal3.077363.72946HepG2PPIG
chr1630230463023117-3'-UTR,CDS,intron-Distal,intron-Proximal3.256306.22359HepG2BUD13
chr1630228383022915-3'-UTR,intron-Distal,intron-Proximal4.8544773.21032K562PABPC4
chr1630228573022923-3'-UTR,intron-Distal,intron-Proximal3.982075.91539HepG2DDX55
chr1630228503022924-3'-UTR,intron-Distal,intron-Proximal3.1033414.50104K562DDX55
chr1630232163023251-3'-UTR,CDS,intron-Distal,intron-Proximal4.020945.99968K562PRPF8
chr1630269603027043-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.389696.11834K562PCBP1
chr1630231483023225-3'-UTR,CDS,intron-Distal,intron-Proximal3.650914.83899HepG2PRPF8
chr1630231363023255-3'-UTR,CDS,intron-Distal,intron-Proximal4.3262221.33032K562AQR
chr1630302863030464-5'-UTR,intron-Distal,intron-Proximal3.5963110.14217HepG2DDX3X
chr1630303083030467-5'-UTR,intron-Distal,intron-Proximal3.512454.77429HepG2NCBP2
chr1630302873030343-5'-UTR,intron-Distal,intron-Proximal3.624245.21590K562DDX3X
chr1630267623026845-CDS,intron-Distal,intron-Proximal3.479404.24993HepG2PPIG
chr1630244743024571-CDS,intron-Distal,intron-Proximal3.245995.23181HepG2PRPF8
chr1630252373025343-CDS,intron-Distal,intron-Proximal4.6795113.40522HepG2PRPF8
chr1630266313026694-CDS,intron-Distal,intron-Proximal4.030483.67792HepG2PRPF8
chr1630246283024695-CDS,intron-Distal,intron-Proximal3.5657216.93904K562AQR
chr1630255993025733-CDS,intron-Distal,intron-Proximal3.085844.57500K562PCBP1
chr1630251953025348-CDS,intron-Distal,intron-Proximal3.6971124.59513K562PRPF8
chr1630268813026960-CDS,intron-Distal,intron-Proximal3.901085.24350K562PCBP1
chr1630256073025731-CDS,intron-Distal,intron-Proximal3.520369.87651HepG2BUD13
chr1630243713024446-CDS,intron-Distal,intron-Proximal3.7069515.01764K562AQR
chr1630245563024602-CDS,intron-Distal4.543904.76200K562BUD13
chr1630243903024431-CDS,intron-Distal,intron-Proximal4.015194.75655HepG2PRPF8
chr1630244813024525-intron-Distal,intron-Proximal4.485233.79199HepG2PPIG
chr1630239043023961-intron-Distal,intron-Proximal5.3443822.69586K562AQR
chr1630278983027940-intron-Distal3.074093.58549K562NONO
chr1630244753024521-intron-Distal,intron-Proximal4.115234.09878HepG2BUD13
chr1630252423025303-intron-Distal,intron-Proximal6.1240542.87447K562AQR
chr1630280923028153-intron-Distal3.132005.38993K562NONO
chr1630244423024490-intron-Distal,intron-Proximal5.803738.93136HepG2EFTUD2
chr1630238953023953-intron-Distal,intron-Proximal5.308095.02942K562EFTUD2
chr1630265853026610-intron-Distal,intron-Proximal4.234654.21433K562PRPF8
chr1630266173026646-intron-Distal,intron-Proximal5.501078.88118K562AQR
chr1630239613024000-intron-Distal,intron-Proximal5.0635915.18812K562AQR
chr1630244763024521-intron-Distal,intron-Proximal3.147466.09777K562PRPF8
chr1630265803026605-intron-Distal,intron-Proximal4.527314.13847K562AQR
chr1630246663024711-intron-Distal,intron-Proximal3.993204.69223K562SF3B4
chr1630276663027735-intron-Distal3.529357.09496K562ILF3
chr1630300453030155-intron-Distal4.359004.76505K562HNRNPK
chr1630253033025320-intron-Distal,intron-Proximal5.0929323.63609K562AQR
chr1630266463026663-intron-Distal,intron-Proximal4.973856.22530K562AQR
chr1630238983023974-intron-Distal,intron-Proximal3.808438.79725K562PRPF8
chr1630271393027197-intron-Distal3.320054.01547K562TIA1
chr1630245073024549-intron-Distal,intron-Proximal5.9211011.25363K562AQR
chr1630276763027760-intron-Distal4.9036311.77263K562GTF2F1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PKMYT1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PKMYT1 is not available on ENCORE database.

  • 112 RBPs can affect the levels of PKMYT1.  








The Knockdown/knockout RNA-Seq assay for PKMYT1 is not available on ENCORE database.





112 RBPs can affect the gene expression of PKMYT1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PKMYT1ENSG00000127564.1251.01010110.00470-1.108702.712701.65190HepG2AATF
PKMYT1ENSG00000127564.12226.86270327.17980-0.528303.629502.94990HepG2ACO1
PKMYT1ENSG00000127564.1225.29590109.42350-2.112903.523202.63850HepG2ASCC1
PKMYT1ENSG00000127564.12230.41360378.63370-0.716602.222601.59520HepG2AUH
PKMYT1ENSG00000127564.1223.12680230.96640-3.3200019.0982017.73450HepG2BOP1
PKMYT1ENSG00000127564.1243.30060161.43200-1.8985011.6685010.26070HepG2CALR
PKMYT1ENSG00000127564.12113.03330327.08610-1.5329020.3086018.87150HepG2CKAP4
PKMYT1ENSG00000127564.1292.43220212.02760-1.197805.904904.93380HepG2CPSF6
PKMYT1ENSG00000127564.12217.57490302.58410-0.475803.173002.28470HepG2DDX19B
PKMYT1ENSG00000127564.1253.94150121.09740-1.166703.171602.44880HepG2DDX21
PKMYT1ENSG00000127564.1232.45660118.72790-1.871105.183203.92450HepG2DDX24
PKMYT1ENSG00000127564.1248.79630107.03360-1.133204.172902.60080HepG2DDX47
PKMYT1ENSG00000127564.12122.03550240.77690-0.980402.828801.83960HepG2DDX59
PKMYT1ENSG00000127564.12132.9636082.407600.690102.585101.90050HepG2DNAJC21
PKMYT1ENSG00000127564.12141.8601081.680900.796303.708402.97320HepG2DNAJC2
PKMYT1ENSG00000127564.1232.35620111.70270-1.787604.761803.30370HepG2AGO1
PKMYT1ENSG00000127564.1228.14710104.59510-1.893803.006402.38890HepG2EIF2S1
PKMYT1ENSG00000127564.12113.39060172.91590-0.608802.477101.67670HepG2EIF4G1
PKMYT1ENSG00000127564.12210.44150434.77010-1.046809.859108.83660HepG2ETF1
PKMYT1ENSG00000127564.1272.32180212.41620-1.554405.797604.33060HepG2FTO
PKMYT1ENSG00000127564.1259.98460109.85090-0.872902.998502.18270HepG2FUBP3
PKMYT1ENSG00000127564.12330.11390116.722301.4998010.394009.13860HepG2FXR1
PKMYT1ENSG00000127564.12113.00220240.31670-1.088604.106403.33870HepG2GPKOW
PKMYT1ENSG00000127564.1293.37390161.08020-0.786703.561902.51980HepG2HNRNPA2B1
PKMYT1ENSG00000127564.12263.05430159.661800.720204.856803.98190HepG2HNRNPL
PKMYT1ENSG00000127564.1279.93420229.34170-1.520608.154507.13660HepG2HNRNPLL
PKMYT1ENSG00000127564.12162.8103091.929800.824503.565502.88500HepG2HNRNPU
PKMYT1ENSG00000127564.1237.47790109.95630-1.552802.480001.83690HepG2IGF2BP2
PKMYT1ENSG00000127564.1289.4017028.908801.628705.877004.04150HepG2KHDRBS1
PKMYT1ENSG00000127564.12396.78590116.763701.7647018.9901017.35510HepG2MAGOH
PKMYT1ENSG00000127564.12280.20220117.393601.255003.220902.54420HepG2MATR3
PKMYT1ENSG00000127564.12100.86380233.97110-1.213902.390501.49610HepG2MTPAP
PKMYT1ENSG00000127564.12200.19540120.139600.736602.280801.70360HepG2NCBP2
PKMYT1ENSG00000127564.12376.22690173.800901.114105.553304.47830HepG2NOL12
PKMYT1ENSG00000127564.12118.0567048.809101.274204.553102.73400HepG2NOLC1
PKMYT1ENSG00000127564.1283.24140203.37930-1.288804.655103.69340HepG2NSUN2
PKMYT1ENSG00000127564.12178.07210128.276600.473101.892001.37370HepG2PCBP1
PKMYT1ENSG00000127564.1235.56630104.89570-1.560402.494001.50880HepG2PCBP2
PKMYT1ENSG00000127564.12170.0775081.994001.052506.174405.10600HepG2PPIL4
PKMYT1ENSG00000127564.1273.70630172.32770-1.225308.029006.79990HepG2PRPF4
PKMYT1ENSG00000127564.1229.37280105.53740-1.845202.763001.95450HepG2PRPF8
PKMYT1ENSG00000127564.12221.80150130.535400.764704.203603.56010HepG2PTBP1
PKMYT1ENSG00000127564.12284.35970176.117100.691105.049704.29690HepG2PUM1
PKMYT1ENSG00000127564.12222.67170350.83460-0.655905.027003.91340HepG2RBM15
PKMYT1ENSG00000127564.1274.84850363.37730-2.2794027.0310025.74320HepG2RBM22
PKMYT1ENSG00000127564.1279.19290128.29480-0.696002.229301.61830HepG2RBM25
PKMYT1ENSG00000127564.1274.7708029.258301.353503.752101.97520HepG2RBM47
PKMYT1ENSG00000127564.12287.52820145.265800.984907.566706.75060HepG2NELFE
PKMYT1ENSG00000127564.12233.21770135.309200.785304.667203.89580HepG2RECQL
PKMYT1ENSG00000127564.1233.57400173.35190-2.3683016.7549015.35280HepG2RPLP0
PKMYT1ENSG00000127564.1255.88690119.56050-1.097202.346601.77530HepG2RPS19
PKMYT1ENSG00000127564.1222.58030104.38230-2.208703.296702.44810HepG2RRP9
PKMYT1ENSG00000127564.12146.6793081.867400.841203.886303.14460HepG2SAFB2
PKMYT1ENSG00000127564.12180.92650304.97460-0.753303.678902.89820HepG2SF3A3
PKMYT1ENSG00000127564.12108.31210226.98380-1.067405.490404.52310HepG2SF3B1
PKMYT1ENSG00000127564.12144.5297095.470900.598102.298201.70340HepG2SMN1
PKMYT1ENSG00000127564.1274.22530252.56620-1.766709.100207.69020HepG2SNRNP70
PKMYT1ENSG00000127564.1288.81840410.40370-2.2081027.0963025.94780HepG2SRFBP1
PKMYT1ENSG00000127564.12103.59330158.09030-0.609802.483801.82050HepG2SRSF7
PKMYT1ENSG00000127564.1257.00400115.40350-1.017604.118003.46960HepG2SRSF9
PKMYT1ENSG00000127564.12167.73330356.29680-1.0869011.0690010.17640HepG2SSB
PKMYT1ENSG00000127564.12319.12360186.296100.776406.415605.53760HepG2SUCLG1
PKMYT1ENSG00000127564.1245.66070136.35510-1.578302.293501.67020HepG2SUPV3L1
PKMYT1ENSG00000127564.1263.20950127.51370-1.012402.745502.18700HepG2TAF15
PKMYT1ENSG00000127564.1287.50060223.62490-1.353706.281705.24940HepG2TARDBP
PKMYT1ENSG00000127564.1251.3243089.32580-0.799402.284501.82140HepG2TIAL1
PKMYT1ENSG00000127564.12141.9865090.125600.655602.581402.03240HepG2TRIM56
PKMYT1ENSG00000127564.1298.80580251.21640-1.346303.985303.23740HepG2U2AF1
PKMYT1ENSG00000127564.12305.76660171.561400.833604.152603.11670HepG2UBE2L3
PKMYT1ENSG00000127564.12109.37410270.46640-1.306209.806108.62970HepG2UPF1
PKMYT1ENSG00000127564.12166.21300277.99770-0.742005.056603.68240HepG2UTP18
PKMYT1ENSG00000127564.12109.62720170.06900-0.633502.816402.13960HepG2ZC3H8
PKMYT1ENSG00000127564.1242.20030297.46050-2.8174043.4627041.97080HepG2ZNF622
PKMYT1ENSG00000127564.121914.334501317.283800.5392010.723809.70010K562AGGF1
PKMYT1ENSG00000127564.121840.211601370.681800.424904.217703.40870K562AKAP8L
PKMYT1ENSG00000127564.12974.616601865.82780-0.936908.868007.91510K562AQR
PKMYT1ENSG00000127564.121693.129001438.153100.235402.133701.33880K562ATP5C1
PKMYT1ENSG00000127564.121121.92540614.153500.869203.789402.65600K562BCLAF1
PKMYT1ENSG00000127564.121152.32410849.831300.439203.132301.99430K562CCAR1
PKMYT1ENSG00000127564.121964.516001508.888800.380605.262603.70430K562CPEB4
PKMYT1ENSG00000127564.121125.38970863.903200.381403.977902.32310K562DDX6
PKMYT1ENSG00000127564.121520.590301165.749100.383304.761403.85070K562EIF2S2
PKMYT1ENSG00000127564.121107.23640801.649700.465805.557103.83430K562EIF4B
PKMYT1ENSG00000127564.121077.43380848.428400.344602.557201.74310K562FIP1L1
PKMYT1ENSG00000127564.12357.06560658.24540-0.882402.517001.44890K562FKBP4
PKMYT1ENSG00000127564.12430.46020583.95090-0.440002.733501.88520K562FMR1
PKMYT1ENSG00000127564.121222.58080925.773800.401104.645103.88810K562FXR1
PKMYT1ENSG00000127564.1232.63860148.44590-2.185305.881004.76370K562G3BP2
PKMYT1ENSG00000127564.121106.84200756.644700.548702.419101.85610K562HNRNPC
PKMYT1ENSG00000127564.12891.688201150.24520-0.367302.457401.70340K562HSPD1
PKMYT1ENSG00000127564.12924.03590360.464201.358004.179702.80900K562IGF2BP2
PKMYT1ENSG00000127564.12595.69550366.495500.700706.081804.21170K562IGF2BP3
PKMYT1ENSG00000127564.12564.947901053.76410-0.899404.518202.66830K562ILF2
PKMYT1ENSG00000127564.12203.34500467.88660-1.202208.964707.17210K562KRR1
PKMYT1ENSG00000127564.12774.89430378.474101.0337015.5190013.39670K562MAGOH
PKMYT1ENSG00000127564.12791.61280377.651601.067604.665103.43550K562MATR3
PKMYT1ENSG00000127564.12733.321001142.22800-0.639304.550303.33050K562NAA15
PKMYT1ENSG00000127564.12832.15260487.384400.771702.532901.31140K562NONO
PKMYT1ENSG00000127564.121612.689301864.48940-0.209302.839502.08430K562NSUN2
PKMYT1ENSG00000127564.121282.02750963.178800.412502.008401.31320K562PPIG
PKMYT1ENSG00000127564.121024.07440678.517500.593802.312101.49150K562PSIP1
PKMYT1ENSG00000127564.121217.42990367.738101.7270027.2679025.27750K562PTBP1
PKMYT1ENSG00000127564.121665.417201359.424100.292802.067801.58560K562PUS1
PKMYT1ENSG00000127564.121365.22050906.729500.590303.558701.36220K562RBFOX2
PKMYT1ENSG00000127564.12600.10190352.420500.767803.224502.31110K562RBM22
PKMYT1ENSG00000127564.12671.51190343.693100.966203.628301.96800K562RBM34
PKMYT1ENSG00000127564.12915.16790619.571000.562702.520501.57770K562RCC2
PKMYT1ENSG00000127564.121149.295101839.84820-0.6788014.7193012.94480K562SF3A3
PKMYT1ENSG00000127564.12302.08980154.112800.970904.671103.54860K562SF3B4
PKMYT1ENSG00000127564.12166.38650291.71870-0.810003.569301.71490K562SND1
PKMYT1ENSG00000127564.12976.33550360.546401.4371025.6886023.53540K562SRSF1
PKMYT1ENSG00000127564.12755.51830339.223201.1551016.3048013.61080K562SRSF4
PKMYT1ENSG00000127564.12661.94500340.608800.958508.754706.79350K562SRSF5
PKMYT1ENSG00000127564.12231.96940327.69100-0.498402.982401.64640K562SSB
PKMYT1ENSG00000127564.12796.630901113.14600-0.482704.151802.45120K562SSRP1
PKMYT1ENSG00000127564.121093.86780364.809401.5841016.2698014.27750K562TARDBP
PKMYT1ENSG00000127564.12952.10200351.922801.4358019.8587017.51710K562TIA1
PKMYT1ENSG00000127564.12809.47750345.546801.2280012.623209.68630K562TRA2A
PKMYT1ENSG00000127564.121509.217201976.96150-0.389506.615605.55860K562UPF1
PKMYT1ENSG00000127564.121210.888801691.61720-0.482305.885204.58590K562WDR3
PKMYT1ENSG00000127564.121031.515101759.12910-0.7701012.7309011.07410K562WDR43
PKMYT1ENSG00000127564.12851.80340501.682100.763603.354701.98170K562XRN2
PKMYT1ENSG00000127564.12610.530901115.30710-0.869304.188802.02240K562YTHDC2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PKMYT1 is not available on ENCORE database.





6 RBPs can affect the splicing of PKMYT1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPKMYT1ENSG00000127564.12chr16-3025982302615630256533025813302666430270320.062000.001970.03601includedK562SRSF1
SEPKMYT1ENSG00000127564.12chr16-3025982302615630256533025813302666430270320.067000.001810.07030includedK562HNRNPK
A3SSPKMYT1ENSG00000127564.12chr16-3023138302344630231383023216302400030241580.051000.000280.03043longerK562AGGF1
A3SSPKMYT1ENSG00000127564.12chr16-3023138302344630231383023216302400030241580.245000.000190.01991longerHepG2SF3A3
A3SSPKMYT1ENSG00000127564.12chr16-3023138302344630231383023216302400030241580.240000.000000.00062longerK562EFTUD2
A3SSPKMYT1ENSG00000127564.12chr16-3026890302705130268903027032302964830299370.070000.003230.01966longerK562AQR
A3SSPKMYT1ENSG00000127564.12chr16-3024550302469930245503024657302531930258130.140000.000110.00093longerK562AQR
A3SSPKMYT1ENSG00000127564.12chr16-3023138302344630231383023254302400030241580.190000.012420.06364longerK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PKMYT1 is not avaliable on ENCORE database.