KDM4A

General Information

Gene Name       : KDM4A
Gene ID             : ENSG00000066135.12
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: KDM4A)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878KDM4AENSG00000066135.1214.0915.8114.95ENCSR000AEF
HepG2KDM4AENSG00000066135.1210.8112.8511.83ENCSR985KAT
K562KDM4AENSG00000066135.1218.0117.7917.90ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for KDM4A is not avaliable on ENCORE database.



Proteins bound to RNA
  • KDM4A RNA is bound by 28 proteins.  







eCLIP assay for KDM4A is not avaliable on ENCORE database.





28 proteins are bound to KDM4A RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr14417046844170540+3'-UTR3.8033320.66113K562FAM120A
chr14417094944171011+3'-UTR4.838646.38441HepG2FAM120A
chr14417095344170997+3'-UTR5.0638421.30813K562FAM120A
chr14417099744171016+3'-UTR4.1919014.32162K562FAM120A
chr14417101244171072+3'-UTR6.1501031.86877K562UPF1
chr14417045144170523+3'-UTR5.200659.46220HepG2UPF1
chr14417096644171012+3'-UTR7.1448235.35557K562UPF1
chr14417096544171019+3'-UTR3.537844.25667K562CSTF2T
chr14417082744170850+3'-UTR3.711573.62890K562FAM120A
chr14417101544171061+3'-UTR3.698934.87041K562GTF2F1
chr14417096644171013+3'-UTR3.882463.90326K562DDX6
chr14417044644170532+3'-UTR5.3490422.12672K562TARDBP
chr14417096144171015+3'-UTR5.357649.13283K562GTF2F1
chr14417056544170639+3'-UTR4.8594712.67045K562UPF1
chr14417045544170525+3'-UTR4.323506.72905K562EIF4G2
chr14417101744171072+3'-UTR4.306463.27332K562DDX6
chr14417096244171038+3'-UTR4.280923.70701HepG2PRPF4
chr14417055944170619+3'-UTR4.037488.13681K562FAM120A
chr14417019644170272+3'-UTR3.901373.28989K562RBM15
chr14417092244171024+3'-UTR4.821916.48468K562FASTKD2
chr14411880544118865+5'-UTR,CDS,intron-Proximal3.995374.26442K562DDX3X
chr14411583244115924+5'-UTR,intron-Proximal3.971193.86664K562DDX3X
chr14416054244160604+CDS,intron-Proximal4.780036.01989HepG2PRPF8
chr14413727444137346+CDS3.097813.17744HepG2GRWD1
chr14412872144128798+CDS,intron-Proximal4.5883613.47152HepG2PRPF8
chr14412125144121315+CDS,intron-Proximal3.192203.01994K562BUD13
chr14412867644128763+CDS,intron-Proximal4.691626.78401HepG2GRWD1
chr14412123544121300+CDS,intron-Proximal3.062475.70281HepG2U2AF2
chr14412857544128621+CDS3.668133.12746HepG2GRWD1
chr14413141244131446+CDS,intron-Proximal4.680265.68502HepG2PRPF8
chr14413131944131421+CDS,intron-Proximal4.229084.77050HepG2SF3B4
chr14412856144128646+CDS,intron-Proximal3.353714.87174HepG2PPIG
chr14412871344128768+CDS,intron-Proximal3.142983.99124HepG2PPIG
chr14413219544132223+CDS3.305323.61259K562ZNF622
chr14412856744128649+CDS4.563239.74753HepG2BCLAF1
chr14415965644159744+CDS,intron-Proximal3.284985.12722K562BUD13
chr14412120144121265+CDS,intron-Proximal5.357987.05392HepG2SF3B4
chr14413477044134823+CDS,intron-Proximal4.624265.29868K562UCHL5
chr14412870244128742+CDS4.715075.37137HepG2BCLAF1
chr14413359044133685+CDS4.081814.76274K562UCHL5
chr14415658444156704+CDS4.291984.11230K562FXR1
chr14412857344128648+CDS3.059623.70975K562UCHL5
chr14413357544133658+CDS3.657767.40563HepG2PPIG
chr14411906744119223+intron-Distal,intron-Proximal3.651536.35344K562PRPF8
chr14414833544148464+intron-Distal4.701113.97018HepG2HNRNPM
chr14413756644137663+intron-Distal,intron-Proximal3.732963.26022HepG2PRPF4
chr14414836644148433+intron-Distal3.685053.04224HepG2SUGP2
chr14414698944147043+intron-Distal3.848023.39864HepG2SUGP2
chr14411628444116382+intron-Distal,intron-Proximal3.425624.35933K562RBFOX2
chr14411767344117758+intron-Distal5.236416.23225K562QKI
chr14413922844139309+intron-Distal3.708466.02668HepG2SUGP2
chr14414630144146373+intron-Distal4.123654.10336HepG2SUGP2
chr14412015144120253+intron-Distal3.201344.06762HepG2U2AF2
chr14414184244141918+intron-Distal3.249763.58557HepG2ILF3
chr14411775444117825+intron-Distal4.310664.80665HepG2QKI
chr14411627744116331+intron-Distal4.458604.24431HepG2RBFOX2
chr14414697444147051+intron-Distal3.770764.28254HepG2MATR3
chr14413497144135046+intron-Proximal4.986074.86944K562AQR
chr14413712444137174+intron-Proximal4.798195.59044HepG2SF3B4
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for KDM4A is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for KDM4A is not available on ENCORE database.

  • 105 RBPs can affect the levels of KDM4A.  








The Knockdown/knockout RNA-Seq assay for KDM4A is not available on ENCORE database.





105 RBPs can affect the gene expression of KDM4A :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
KDM4AENSG00000066135.81503.64870799.256600.9116012.3501010.59590HepG2ABCF1
KDM4AENSG00000066135.81002.45630632.079000.6653012.0515010.97300HepG2ACO1
KDM4AENSG00000066135.8706.55450523.880800.431502.911401.88930HepG2ADAR
KDM4AENSG00000066135.81070.19690753.734200.505603.394402.81350HepG2AKAP1
KDM4AENSG00000066135.81090.17790634.975600.7797015.3522013.75060HepG2AKAP8L
KDM4AENSG00000066135.8905.47900623.652300.537804.196603.23800HepG2ASCC1
KDM4AENSG00000066135.8881.686401219.94990-0.468506.832705.83070HepG2AUH
KDM4AENSG00000066135.8880.49170641.931600.455802.821201.91460HepG2BCLAF1
KDM4AENSG00000066135.81290.35260592.512401.1227017.6966015.95230HepG2CIRBP
KDM4AENSG00000066135.81098.59730631.853700.7979018.4526017.06520HepG2CKAP4
KDM4AENSG00000066135.8813.92950504.233900.690704.053003.12120HepG2CNOT7
KDM4AENSG00000066135.8673.71550835.40690-0.310302.946702.18530HepG2DAZAP1
KDM4AENSG00000066135.8852.12460584.542100.543708.205006.90130HepG2DDX19B
KDM4AENSG00000066135.81264.65930556.592501.1840022.2777020.60430HepG2DDX21
KDM4AENSG00000066135.8839.77900544.376500.625306.621905.21510HepG2DDX24
KDM4AENSG00000066135.81270.64200722.021500.815309.297808.20910HepG2DDX3X
KDM4AENSG00000066135.81271.22840604.705601.0718028.1055026.51480HepG2DKC1
KDM4AENSG00000066135.8415.74290527.50350-0.343502.275901.63320HepG2DNAJC21
KDM4AENSG00000066135.8803.15860465.163100.787807.509206.07220HepG2EEF2
KDM4AENSG00000066135.8570.42680387.756400.556803.835302.52150HepG2EFTUD2
KDM4AENSG00000066135.8462.58950596.24360-0.366201.888201.38760HepG2EIF2S1
KDM4AENSG00000066135.8827.30670606.494800.447804.136302.71730HepG2EIF2S2
KDM4AENSG00000066135.8637.91090377.592700.756406.156604.84650HepG2EIF3D
KDM4AENSG00000066135.8910.76880525.416900.7935010.798008.95270HepG2EIF3G
KDM4AENSG00000066135.81197.53250658.920500.861809.257208.09710HepG2EIF4A3
KDM4AENSG00000066135.81313.48870641.549101.0337010.520709.22350HepG2EIF4B
KDM4AENSG00000066135.8956.28630692.521300.465504.061302.75900HepG2ESF1
KDM4AENSG00000066135.82570.823001400.710200.8760028.6453027.05160HepG2ETF1
KDM4AENSG00000066135.81111.97200617.576100.8483013.0838011.32540HepG2EWSR1
KDM4AENSG00000066135.81099.17900807.109800.445503.097902.28790HepG2FIP1L1
KDM4AENSG00000066135.8956.04190664.819300.524004.099303.26880HepG2FXR1
KDM4AENSG00000066135.8983.02440616.719400.672506.045805.07950HepG2G3BP1
KDM4AENSG00000066135.8959.36570654.724000.551104.593203.43410HepG2G3BP2
KDM4AENSG00000066135.8723.85230336.192801.1063013.3816011.52790HepG2GEMIN5
KDM4AENSG00000066135.8836.77830636.880600.393702.387301.44540HepG2GNB2L1
KDM4AENSG00000066135.81178.16450888.970700.406202.732002.09460HepG2GPKOW
KDM4AENSG00000066135.8960.84600532.557600.8513011.074909.91500HepG2HNRNPA1
KDM4AENSG00000066135.81062.748101252.03410-0.236502.309801.65030HepG2HNRNPF
KDM4AENSG00000066135.8788.63110624.479500.336601.985001.38640HepG2HNRNPK
KDM4AENSG00000066135.8536.00650760.97530-0.505606.318905.33940HepG2HNRNPL
KDM4AENSG00000066135.8728.63870557.016500.387403.052602.05550HepG2HNRNPM
KDM4AENSG00000066135.8801.77130588.468800.446105.058704.25920HepG2HNRNPU
KDM4AENSG00000066135.81275.51940626.882601.0247014.7167013.29690HepG2IGF2BP2
KDM4AENSG00000066135.81444.73260870.234100.731206.562305.27160HepG2LARP4
KDM4AENSG00000066135.81067.91160665.051300.683206.543305.54500HepG2MAGOH
KDM4AENSG00000066135.81518.71110668.774201.1832017.2820015.81230HepG2MATR3
KDM4AENSG00000066135.81301.50650684.528100.9269011.5048010.25570HepG2NCBP2
KDM4AENSG00000066135.8673.37420828.39060-0.298902.150501.47670HepG2NOL12
KDM4AENSG00000066135.8508.46150752.20010-0.565004.309703.38170HepG2NSUN2
KDM4AENSG00000066135.8711.60080532.444200.418303.062201.37000HepG2NUP35
KDM4AENSG00000066135.8748.27040582.465200.361303.255002.34340HepG2PARN
KDM4AENSG00000066135.81111.27080616.614300.8497017.9602016.62980HepG2PCBP1
KDM4AENSG00000066135.81020.96920622.502400.713705.044803.67540HepG2PCBP2
KDM4AENSG00000066135.8955.93550654.363900.546703.053401.78170HepG2PRPF6
KDM4AENSG00000066135.81098.22770560.274300.9709011.7452010.24550HepG2PRPF8
KDM4AENSG00000066135.81243.79430627.415800.9872024.5481023.22720HepG2PTBP1
KDM4AENSG00000066135.81181.18550790.786400.578806.718105.84280HepG2PUF60
KDM4AENSG00000066135.81446.06020839.472200.7845012.6081011.53770HepG2PUM1
KDM4AENSG00000066135.81094.48060838.848100.383703.702702.93210HepG2PUM2
KDM4AENSG00000066135.81309.20360643.800601.0239030.0823028.44920HepG2PUS1
KDM4AENSG00000066135.8832.78120679.533000.293302.018701.47250HepG2QKI
KDM4AENSG00000066135.82117.609601170.725200.8549011.9809011.05880HepG2RBM22
KDM4AENSG00000066135.8822.43850616.710000.415203.258602.53320HepG2RBM25
KDM4AENSG00000066135.81394.79670698.263800.9981024.8086023.51100HepG2NELFE
KDM4AENSG00000066135.8954.48490650.319300.553507.356606.42350HepG2RECQL
KDM4AENSG00000066135.81810.664401348.814300.424703.945403.15330HepG2RPLP0
KDM4AENSG00000066135.8827.62280590.207400.487702.472501.57890HepG2RPS10
KDM4AENSG00000066135.8914.49990367.431501.3154024.0713022.54730HepG2RPS19
KDM4AENSG00000066135.81069.72490693.953200.624205.890004.74640HepG2RPS2
KDM4AENSG00000066135.8750.57100554.217100.437402.337101.60810HepG2RRP9
KDM4AENSG00000066135.8422.28480524.04890-0.311502.170101.58730HepG2SAFB2
KDM4AENSG00000066135.8551.07890368.747600.579504.092502.95330HepG2SERBP1
KDM4AENSG00000066135.81719.79370814.565101.0780012.1706010.69820HepG2SF3A3
KDM4AENSG00000066135.81112.52010839.730700.405703.252702.49310HepG2SF3B1
KDM4AENSG00000066135.81134.85440653.242900.7967015.3252014.10260HepG2SF3B4
KDM4AENSG00000066135.8482.79250758.27690-0.651309.381908.21100HepG2SLBP
KDM4AENSG00000066135.8798.83860611.115200.386404.408003.62980HepG2SMN1
KDM4AENSG00000066135.81621.516101322.274700.294202.949902.43790HepG2SRFBP1
KDM4AENSG00000066135.81602.26250681.835201.2325041.6187040.26230HepG2SRSF1
KDM4AENSG00000066135.81476.00450780.807400.9186025.0506023.44010HepG2SRSF5
KDM4AENSG00000066135.82297.278001148.018901.0007038.3529036.95960HepG2SSB
KDM4AENSG00000066135.81483.90630887.975100.740707.813406.85510HepG2SUCLG1
KDM4AENSG00000066135.81060.26360723.113800.552003.718702.95090HepG2SUPV3L1
KDM4AENSG00000066135.81306.15560673.604800.955305.368503.92160HepG2TBRG4
KDM4AENSG00000066135.8780.07340571.753000.448104.145103.55980HepG2TIAL1
KDM4AENSG00000066135.8385.87230576.92240-0.580305.802605.03990HepG2TRIM56
KDM4AENSG00000066135.8451.45330300.031300.589403.382601.64110HepG2TROVE2
KDM4AENSG00000066135.81119.40490772.593400.534906.067104.70590HepG2TUFM
KDM4AENSG00000066135.81069.29970690.561500.630706.608705.65100HepG2U2AF1
KDM4AENSG00000066135.8302.37430427.14520-0.498402.943002.16300HepG2UCHL5
KDM4AENSG00000066135.8897.08530722.392800.312403.066002.33880HepG2UPF1
KDM4AENSG00000066135.81009.32000742.533500.442805.326403.91510HepG2UTP18
KDM4AENSG00000066135.8940.56210697.444800.431304.867704.11010HepG2UTP3
KDM4AENSG00000066135.81024.39710660.627100.632804.313403.00230HepG2XRCC6
KDM4AENSG00000066135.81952.400302431.69790-0.316704.687203.98270K562AGGF1
KDM4AENSG00000066135.81904.729002530.28160-0.409704.312603.49180K562AKAP8L
KDM4AENSG00000066135.8662.46750901.61280-0.444702.753601.44570K562BCCIP
KDM4AENSG00000066135.8333.25650596.60720-0.840108.493406.26660K562DNAJC21
KDM4AENSG00000066135.81779.845901010.915000.8160019.8716018.20580K562EIF2S2
KDM4AENSG00000066135.8646.328001084.97190-0.7473012.2594010.55970K562EIF3G
KDM4AENSG00000066135.81083.85300868.410500.319602.915601.72240K562EIF4B
KDM4AENSG00000066135.8333.58990773.91660-1.2141019.1059017.61470K562HNRNPC
KDM4AENSG00000066135.82144.105101285.388600.7381010.702609.16380K562HSPD1
KDM4AENSG00000066135.82131.785802685.29700-0.333002.872002.02930K562KIF1C
KDM4AENSG00000066135.81006.185901391.19320-0.467403.848602.84950K562MAGOH
KDM4AENSG00000066135.8734.192301021.87260-0.477006.303905.12580K562MTPAP
KDM4AENSG00000066135.81247.61490962.942300.373603.587102.16740K562NCBP2
KDM4AENSG00000066135.81031.447001322.49760-0.358602.343101.57790K562PCBP3
KDM4AENSG00000066135.81007.73610801.676300.329902.045201.39580K562PRPF8
KDM4AENSG00000066135.8801.440001351.69220-0.754107.602506.53800K562PTBP1
KDM4AENSG00000066135.81848.279602509.41830-0.441204.718604.03400K562PUS1
KDM4AENSG00000066135.81810.891702444.98940-0.433106.522405.63750K562RBM15
KDM4AENSG00000066135.81689.498201277.493400.403204.152202.18670K562RBM17
KDM4AENSG00000066135.8994.827201295.66700-0.381202.838501.98660K562RBM22
KDM4AENSG00000066135.8880.754201363.58620-0.630605.423103.82160K562NELFE
KDM4AENSG00000066135.8828.867501068.57360-0.366504.411602.42090K562RPS10
KDM4AENSG00000066135.8939.413501120.37250-0.254102.059201.34830K562SF3A3
KDM4AENSG00000066135.8384.38610611.09160-0.668805.903404.05280K562SLBP
KDM4AENSG00000066135.8460.13300600.33720-0.383702.318101.39780K562SRFBP1
KDM4AENSG00000066135.8801.876701325.20030-0.724806.778905.68190K562SRSF1
KDM4AENSG00000066135.81454.195001119.158400.377703.323801.89910K562SSB
KDM4AENSG00000066135.8919.516701340.99240-0.544404.865603.91370K562TARDBP
KDM4AENSG00000066135.81611.590001293.590300.317002.157301.44190K562TIA1
KDM4AENSG00000066135.8930.063901354.37030-0.542204.500302.95990K562UTP3
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for KDM4A is not available on ENCORE database.





4 RBPs can affect the splicing of KDM4A :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEKDM4AENSG00000066135.8chr1+4411933344119470441189764411898444121261441214370.148000.001280.04519includedK562PRPF8
SEKDM4AENSG00000066135.8chr1+4411933344119470441189764411898444121261441214370.076000.003590.03541includedK562AQR
SEKDM4AENSG00000066135.8chr1+4411933344119470441189764411898444121261441214370.101000.006050.08068includedK562HNRNPC
A3SSKDM4AENSG00000066135.8chr1+4413475044134970441347704413497044133442441336900.078000.000120.00103longerK562AQR
A5SSKDM4AENSG00000066135.8chr1+4415458444154830441545844415476644156515441567200.075000.000070.00418longerK562PUS1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for KDM4A is not avaliable on ENCORE database.