HYAL1

General Information

Gene Name       : HYAL1
Gene ID             : ENSG00000114378.16
Essential Gene : No

Functions

Localization

Domains (AlphaFold: HYAL1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878HYAL1ENSG00000114378.160.000.050.03ENCSR000AEF
HepG2HYAL1ENSG00000114378.1697.1850.9774.08ENCSR985KAT
K562HYAL1ENSG00000114378.165.425.215.31ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for HYAL1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • HYAL1 RNA is bound by 14 proteins.  







eCLIP assay for HYAL1 is not avaliable on ENCORE database.





14 proteins are bound to HYAL1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr35033791550337967-3'-UTR,CDS,intron-Distal4.8454817.99633HepG2SND1
chr35033760550337684-3'-UTR,intron-Distal,intron-Proximal3.7276011.27814HepG2IGF2BP1
chr35033781950337876-3'-UTR,intron-Distal,intron-Proximal3.195257.37825HepG2IGF2BP1
chr35033776250337874-3'-UTR,intron-Distal,intron-Proximal4.629817.35927HepG2IGF2BP3
chr35033774950337819-3'-UTR,intron-Distal,intron-Proximal3.510186.35138HepG2IGF2BP1
chr35033774650337866-3'-UTR,intron-Distal,intron-Proximal3.1619910.67677HepG2HNRNPL
chr35033790150337975-3'-UTR,CDS,intron-Distal,intron-Proximal3.022966.75501HepG2RPS3
chr35033760350337703-3'-UTR,intron-Distal,intron-Proximal3.689024.54434HepG2UPF1
chr35033760150337740-3'-UTR,intron-Distal,intron-Proximal4.3802312.02391HepG2IGF2BP3
chr35033783250337903-3'-UTR,intron-Distal,intron-Proximal3.935484.09643HepG2YBX3
chr35033739050337442-3'-UTR,intron-Distal3.870963.33095HepG2IGF2BP3
chr35034036050340448-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal4.0845321.24160HepG2DDX3X
chr35033985550339953-5'-UTR,CDS,intron-Distal4.8894228.89340HepG2SND1
chr35034081550340887-5'-UTR,intron-Distal3.090223.59357HepG2NKRF
chr35034072250340777-5'-UTR,intron-Distal4.7020111.01919HepG2DDX3X
chr35033977650339855-5'-UTR,CDS,intron-Distal4.2264020.43665HepG2SND1
chr35033996350340021-5'-UTR,CDS,intron-Distal,intron-Proximal4.0047617.08371HepG2SND1
chr35034088450340922-5'-UTR,intron-Distal4.341949.09300HepG2DDX3X
chr35033961050339650-5'-UTR,CDS,intron-Distal,intron-Proximal3.592008.92528HepG2SND1
chr35034003850340086-5'-UTR,CDS,intron-Distal,intron-Proximal4.0503814.34717HepG2SND1
chr35034092250341000-5'-UTR,intron-Distal4.5074626.93048HepG2DDX3X
chr35033952650339596-CDS,intron-Distal5.8112926.16051HepG2SND1
chr35033821250338286-CDS,intron-Distal3.197279.54321HepG2BUD13
chr35034027850340314-CDS,intron-Distal3.614825.36532HepG2DDX3X
chr35034008650340165-CDS,intron-Distal,intron-Proximal4.3404019.12916HepG2SND1
chr35034023450340266-CDS,intron-Distal4.912628.88833HepG2DDX3X
chr35033802350338068-CDS,intron-Distal3.845745.47244HepG2LARP4
chr35033844450338508-CDS,intron-Distal4.9432221.22688HepG2SND1
chr35033821650338287-CDS,intron-Distal3.686766.43894HepG2SF3A3
chr35033963850339692-CDS,intron-Distal,intron-Proximal3.907845.96402HepG2RPS3
chr35033948950339497-CDS,intron-Distal4.012696.35450HepG2SND1
chr35033970050339747-CDS,intron-Distal,intron-Proximal4.3508317.43706HepG2SND1
chr35034020550340238-CDS,intron-Distal5.436075.67454HepG2RPS3
chr35033823250338329-intron-Distal,intron-Proximal4.275883.74254HepG2SF3B4
chr35033831050338382-intron-Distal,intron-Proximal5.1574316.57785HepG2EFTUD2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for HYAL1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for HYAL1 is not available on ENCORE database.

  • 113 RBPs can affect the levels of HYAL1.  








The Knockdown/knockout RNA-Seq assay for HYAL1 is not available on ENCORE database.





113 RBPs can affect the gene expression of HYAL1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
HYAL1ENSG00000114378.121086.053401478.64060-0.445204.226802.92850HepG2AATF
HYAL1ENSG00000114378.121789.540902332.19340-0.382107.373506.47880HepG2ACO1
HYAL1ENSG00000114378.121597.205004248.53230-1.4114028.6225027.12780HepG2AKAP1
HYAL1ENSG00000114378.122721.241603359.72660-0.304104.819603.95490HepG2AUH
HYAL1ENSG00000114378.122325.219901481.497100.650205.147403.95720HepG2BCLAF1
HYAL1ENSG00000114378.121510.097602024.23490-0.422704.283103.55690HepG2BOP1
HYAL1ENSG00000114378.122776.125102331.507200.251704.206603.41900HepG2CKAP4
HYAL1ENSG00000114378.122571.168101858.313500.468304.972704.07390HepG2CPSF6
HYAL1ENSG00000114378.123279.876802492.733700.3958010.137208.85820HepG2DAZAP1
HYAL1ENSG00000114378.122518.286402156.862300.223402.648601.83060HepG2DDX19B
HYAL1ENSG00000114378.122605.064501630.576300.6758010.647309.41300HepG2DDX21
HYAL1ENSG00000114378.123242.884004069.55440-0.327602.470801.87670HepG2DDX3X
HYAL1ENSG00000114378.124156.399702565.380300.6961010.798808.95820HepG2DDX5
HYAL1ENSG00000114378.123176.893502231.230700.5097012.0561010.85050HepG2DKC1
HYAL1ENSG00000114378.121996.186101524.542200.388803.727602.91890HepG2DNAJC21
HYAL1ENSG00000114378.122257.620801511.160500.5790016.9966015.51360HepG2DNAJC2
HYAL1ENSG00000114378.122427.981301861.185200.383403.228602.23810HepG2EEF2
HYAL1ENSG00000114378.121153.970001510.78560-0.388703.304302.32270HepG2EIF3D
HYAL1ENSG00000114378.122377.132303616.20500-0.605304.908904.00960HepG2EIF4B
HYAL1ENSG00000114378.121886.881502459.33380-0.382305.563404.44660HepG2EIF4G1
HYAL1ENSG00000114378.121748.794002278.81040-0.381904.194103.16590HepG2EWSR1
HYAL1ENSG00000114378.123937.041702904.101500.438903.528102.66610HepG2FIP1L1
HYAL1ENSG00000114378.123141.954102332.188200.429903.390601.55590HepG2FMR1
HYAL1ENSG00000114378.122211.190302812.30660-0.346903.578902.69090HepG2FUBP3
HYAL1ENSG00000114378.122923.102403747.63740-0.358502.987502.26750HepG2FXR1
HYAL1ENSG00000114378.122405.895003476.09060-0.530905.227204.32600HepG2G3BP1
HYAL1ENSG00000114378.122148.600501626.287700.401702.549601.57720HepG2GNB2L1
HYAL1ENSG00000114378.123543.418602106.421500.750209.680508.53210HepG2GPKOW
HYAL1ENSG00000114378.122238.818001539.148600.540504.409803.61910HepG2HNRNPA1
HYAL1ENSG00000114378.122875.226701712.045000.747909.847708.60630HepG2HNRNPC
HYAL1ENSG00000114378.123119.565002682.717300.217502.634901.93450HepG2HNRNPF
HYAL1ENSG00000114378.122189.222003520.77330-0.6855010.545609.26040HepG2HNRNPK
HYAL1ENSG00000114378.123964.069902010.207900.9795018.8567017.43200HepG2HNRNPLL
HYAL1ENSG00000114378.122465.816602003.418800.299502.656001.72160HepG2HNRNPM
HYAL1ENSG00000114378.122339.795901700.724000.460109.678608.60030HepG2HNRNPU
HYAL1ENSG00000114378.121943.780103316.34680-0.770702.719201.74400HepG2IGF2BP3
HYAL1ENSG00000114378.122173.288201737.228700.323006.257505.19840HepG2ILF2
HYAL1ENSG00000114378.12810.417101236.22950-0.609204.070702.43800HepG2ILF3
HYAL1ENSG00000114378.122685.618602131.805600.333106.907405.34590HepG2KIF1C
HYAL1ENSG00000114378.123993.573802999.229900.413002.871302.02580HepG2LARP4
HYAL1ENSG00000114378.122819.515103769.81010-0.419003.351802.66350HepG2MATR3
HYAL1ENSG00000114378.122207.152401782.522000.308202.500801.78880HepG2NSUN2
HYAL1ENSG00000114378.122467.084101683.392200.5513012.6273011.03190HepG2PARN
HYAL1ENSG00000114378.122225.952801516.905300.5532010.590509.19650HepG2PPIL4
HYAL1ENSG00000114378.123017.102003768.65520-0.320905.864505.12770HepG2PTBP1
HYAL1ENSG00000114378.124776.839702359.577201.0174027.2575025.64960HepG2PUF60
HYAL1ENSG00000114378.123599.273702375.464000.5994019.7093018.33310HepG2PUS1
HYAL1ENSG00000114378.123159.237704081.69160-0.369605.722004.87150HepG2QKI
HYAL1ENSG00000114378.12873.033301539.61300-0.818503.251202.48960HepG2RAVER1
HYAL1ENSG00000114378.122497.452303213.18110-0.363503.620102.65390HepG2RBM15
HYAL1ENSG00000114378.121710.551803224.16160-0.9145029.8808028.54220HepG2RBM22
HYAL1ENSG00000114378.122617.011203704.34270-0.501307.671206.59660HepG2RBM25
HYAL1ENSG00000114378.122556.627001921.860000.411602.811101.81160HepG2RBM27
HYAL1ENSG00000114378.121736.964304194.20800-1.2718070.5569068.73630HepG2NELFE
HYAL1ENSG00000114378.123023.753303906.23220-0.369407.651306.70210HepG2RECQL
HYAL1ENSG00000114378.122048.011402889.96570-0.496806.028205.07700HepG2RPLP0
HYAL1ENSG00000114378.122004.043101273.509100.654005.394704.27120HepG2RPS3A
HYAL1ENSG00000114378.121610.262501199.224700.425102.676301.38670HepG2SART3
HYAL1ENSG00000114378.121877.710201475.385500.347802.580301.67200HepG2SERBP1
HYAL1ENSG00000114378.122258.423402890.13420-0.355801.862701.30690HepG2SF3A3
HYAL1ENSG00000114378.121520.064601989.63850-0.388403.229802.47140HepG2SF3B1
HYAL1ENSG00000114378.122306.273203923.77850-0.7667028.3190026.76860HepG2SF3B4
HYAL1ENSG00000114378.123208.970902262.543000.5041015.6444014.22530HepG2SLBP
HYAL1ENSG00000114378.122359.504301766.199600.4177010.101108.99630HepG2SMN1
HYAL1ENSG00000114378.122153.788201573.175400.453102.590901.66580HepG2SMNDC1
HYAL1ENSG00000114378.122182.801401501.417300.539803.451001.65510HepG2SND1
HYAL1ENSG00000114378.122259.941401184.267100.932203.113701.70260HepG2SNRNP200
HYAL1ENSG00000114378.121514.317903641.52730-1.2659076.0069074.30620HepG2SRFBP1
HYAL1ENSG00000114378.121614.161004095.52550-1.3433085.1378083.35760HepG2SRSF1
HYAL1ENSG00000114378.123064.678102635.686200.217502.709302.02020HepG2SRSF7
HYAL1ENSG00000114378.122420.496903331.88520-0.4610011.4694010.48110HepG2SRSF9
HYAL1ENSG00000114378.123882.501103161.630000.296205.233604.57170HepG2SSB
HYAL1ENSG00000114378.121938.610703681.07980-0.9251031.4073029.78310HepG2TAF15
HYAL1ENSG00000114378.122905.270701959.652700.568007.307806.20540HepG2TARDBP
HYAL1ENSG00000114378.125165.453503056.184800.757103.859902.61230HepG2TBRG4
HYAL1ENSG00000114378.12539.549701118.54610-1.051806.209904.81330HepG2TFIP11
HYAL1ENSG00000114378.122478.856003382.55750-0.448405.862004.65780HepG2TIA1
HYAL1ENSG00000114378.121995.196001652.470900.271802.625402.13610HepG2TIAL1
HYAL1ENSG00000114378.123027.835501667.350400.8606032.7342031.06230HepG2TRIM56
HYAL1ENSG00000114378.123356.084802305.267700.541708.821507.10220HepG2TUFM
HYAL1ENSG00000114378.121645.468102484.01090-0.594207.508706.48010HepG2U2AF1
HYAL1ENSG00000114378.12712.00410985.78300-0.469402.165701.49380HepG2UCHL5
HYAL1ENSG00000114378.123619.025002563.109100.4976013.8045012.47180HepG2UPF1
HYAL1ENSG00000114378.121532.199201140.697100.425602.459701.43420HepG2XPO5
HYAL1ENSG00000114378.121658.493202189.40650-0.400708.352307.29010HepG2ZC3H8
HYAL1ENSG00000114378.123737.279502818.926600.4067011.9290010.99120HepG2ZNF622
HYAL1ENSG00000114378.122257.873501539.318000.552604.181102.55350HepG2ZRANB2
HYAL1ENSG00000114378.12175.44040270.07080-0.622402.859301.59790K562APOBEC3C
HYAL1ENSG00000114378.12249.03830164.188700.600903.220302.18510K562BCLAF1
HYAL1ENSG00000114378.12308.27910177.632700.795202.842101.76170K562CNOT7
HYAL1ENSG00000114378.12355.68030257.459500.466102.550201.48850K562CPEB4
HYAL1ENSG00000114378.1284.12390143.96550-0.775103.464101.96870K562DDX27
HYAL1ENSG00000114378.1258.98930266.45390-2.1754026.0410024.23380K562DDX47
HYAL1ENSG00000114378.12210.62250125.526200.746603.748002.16640K562DNAJC21
HYAL1ENSG00000114378.1285.53230163.84390-0.937802.603801.36440K562EEF2
HYAL1ENSG00000114378.12171.84980101.822900.755003.615002.21210K562EIF2S1
HYAL1ENSG00000114378.1256.97930187.36690-1.7174013.6870012.27210K562EIF2S2
HYAL1ENSG00000114378.1236.84400118.73610-1.688304.677703.33720K562EIF3A
HYAL1ENSG00000114378.1284.50960169.34910-1.002802.727001.69950K562EIF3D
HYAL1ENSG00000114378.12241.2116096.857501.3163010.151908.56290K562EIF4A3
HYAL1ENSG00000114378.12203.84490306.06880-0.586403.196502.18940K562EIF4G2
HYAL1ENSG00000114378.1263.19260100.72680-0.672601.963001.43650K562FXR1
HYAL1ENSG00000114378.12282.03500148.715800.923203.887802.95310K562GPKOW
HYAL1ENSG00000114378.1269.25470121.27910-0.808302.441701.57040K562HNRNPM
HYAL1ENSG00000114378.1279.88880199.88160-1.323108.206406.84970K562HSPD1
HYAL1ENSG00000114378.12216.42630145.171600.576002.444601.62550K562METAP2
HYAL1ENSG00000114378.12583.22130326.240400.838007.874006.02260K562MSI2
HYAL1ENSG00000114378.12341.83140258.321000.404002.341501.64980K562NSUN2
HYAL1ENSG00000114378.12306.90310170.655200.846602.998101.70590K562PABPC1
HYAL1ENSG00000114378.12111.15120232.12380-1.062406.021204.78870K562PCBP3
HYAL1ENSG00000114378.1286.45230178.05430-1.042305.788504.63380K562POLR2G
HYAL1ENSG00000114378.1234.04760153.99940-2.177307.046805.85150K562PRPF8
HYAL1ENSG00000114378.12134.3316072.978600.880203.852503.08060K562PTBP1
HYAL1ENSG00000114378.12147.4797069.959301.075805.353504.13970K562RBM22
HYAL1ENSG00000114378.1239.2818073.62530-0.906302.405001.39900K562NELFE
HYAL1ENSG00000114378.1236.47160156.80000-2.104107.382006.03390K562RPS19
HYAL1ENSG00000114378.1275.66950158.62750-1.067904.921603.47840K562SAFB
HYAL1ENSG00000114378.12167.4015086.981600.944402.692301.41460K562SFPQ
HYAL1ENSG00000114378.12208.61350128.546000.698403.460702.02930K562SLBP
HYAL1ENSG00000114378.12191.43560261.10980-0.447802.297601.43630K562SRPK2
HYAL1ENSG00000114378.12237.18320148.987300.670702.712601.70590K562SUPV3L1
HYAL1ENSG00000114378.1257.00120178.58290-1.6475011.440209.78150K562SYNCRIP
HYAL1ENSG00000114378.12156.4612072.402201.111605.232504.24260K562TARDBP
HYAL1ENSG00000114378.12205.05490135.292500.599802.181301.35660K562TRIM56
HYAL1ENSG00000114378.12547.17330376.508600.539203.962802.27700K562UBE2L3
HYAL1ENSG00000114378.12376.80060273.901400.460003.045002.29230K562UPF1
HYAL1ENSG00000114378.12153.47600234.37170-0.610803.132002.20360K562WDR3
HYAL1ENSG00000114378.1262.39650243.69930-1.9656022.3247020.27470K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for HYAL1 is not available on ENCORE database.





13 RBPs can affect the splicing of HYAL1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEHYAL1ENSG00000114378.12chr3-503384185033850850337912503382315033948750340054-0.205000.000000.00000excludedHepG2U2AF1
SEHYAL1ENSG00000114378.12chr3-5033948750340411503377415033823150340896503410510.099000.000870.01255includedHepG2U2AF2
SEHYAL1ENSG00000114378.12chr3-503384185033850850337912503382315033948750340054-0.376000.000000.00000excludedHepG2U2AF2
SEHYAL1ENSG00000114378.12chr3-5033841850338561503373205033823150339487503400540.433000.010050.08162includedK562AQR
SEHYAL1ENSG00000114378.12chr3-503384185033850850337912503382315033948750340054-0.089000.000090.01205excludedHepG2DDX3X
SEHYAL1ENSG00000114378.12chr3-5033841850338508503379125033823150339487503400540.072000.000090.02219includedHepG2TIA1
SEHYAL1ENSG00000114378.12chr3-503384185033850850337912503382315033948750340054-0.080000.000430.03094excludedHepG2NCBP2
SEHYAL1ENSG00000114378.12chr3-503384185033850850337912503382315033948750340054-0.075000.000310.01902excludedHepG2SFPQ
SEHYAL1ENSG00000114378.12chr3-503384185033850850337912503382315033948750340054-0.102000.000000.00239excludedHepG2HNRNPUL1
SEHYAL1ENSG00000114378.12chr3-503384185033850850337912503382315033948750340054-0.113000.000050.00258excludedHepG2SF3A3
SEHYAL1ENSG00000114378.12chr3-503384185033850850337912503382315033948750340054-0.140000.000000.00008excludedHepG2SF3B4
SEHYAL1ENSG00000114378.12chr3-503384185033850850337912503382315033948750340054-0.147000.000000.00043excludedHepG2HNRNPU
A3SSHYAL1ENSG00000114378.12chr3-5033948750340411503394875034005450340896503410040.062000.000000.00026longerHepG2HNRNPK
A3SSHYAL1ENSG00000114378.12chr3-5033948750340411503394875034005450340896503410040.079000.000010.02068longerHepG2LARP4

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for HYAL1 is not avaliable on ENCORE database.