GJB1

General Information

Gene Name       : GJB1
Gene ID             : ENSG00000169562.10
Essential Gene : No

Functions

Localization

Domains (AlphaFold: GJB1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878GJB1ENSG00000169562.100.000.000.00ENCSR000AEF
HepG2GJB1ENSG00000169562.10107.8353.7480.78ENCSR985KAT
K562GJB1ENSG00000169562.100.000.000.00ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for GJB1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • GJB1 RNA is bound by 11 proteins.  







eCLIP assay for GJB1 is not avaliable on ENCORE database.





11 proteins are bound to GJB1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chrX7044461070444701+3'-UTR5.5202843.69383HepG2AKAP1
chrX7044451770444609+3'-UTR5.8588049.46481HepG2AKAP1
chrX7044491770444991+3'-UTR4.325904.86307HepG2PRPF4
chrX7044440270444464+3'-UTR,CDS6.1055263.55821HepG2UPF1
chrX7044478970444846+3'-UTR6.6171922.73714HepG2AKAP1
chrX7044456170444598+3'-UTR7.1618336.18746HepG2UPF1
chrX7044487170444912+3'-UTR3.755165.61462HepG2PRPF4
chrX7044452570444612+3'-UTR3.092738.27114HepG2LARP4
chrX7044440370444492+3'-UTR,CDS5.1538814.02346HepG2PCBP1
chrX7044461270444689+3'-UTR3.2402913.71824HepG2LARP4
chrX7044443970444489+3'-UTR3.027136.41962HepG2RPS3
chrX7044493870445010+3'-UTR5.0759725.69586HepG2AKAP1
chrX7044486470444929+3'-UTR6.7089384.22664HepG2UPF1
chrX7044494770445006+3'-UTR7.7642365.41518HepG2UPF1
chrX7044476370444864+3'-UTR6.5527676.71639HepG2UPF1
chrX7044459870444690+3'-UTR5.9448276.36293HepG2UPF1
chrX7044451570444561+3'-UTR7.4840144.50262HepG2UPF1
chrX7044493170445005+3'-UTR5.2527016.50828HepG2LARP4
chrX7044441070444510+3'-UTR4.1945316.69050HepG2LARP4
chrX7044484870444993+3'-UTR3.013756.21540HepG2G3BP1
chrX7044486070444931+3'-UTR6.0644414.16859HepG2LARP4
chrX7044489870444938+3'-UTR6.4013823.17923HepG2AKAP1
chrX7044474770444789+3'-UTR5.1249315.83215HepG2AKAP1
chrX7044492970444947+3'-UTR6.1932541.55129HepG2UPF1
chrX7044441070444517+3'-UTR4.2099235.25477HepG2AKAP1
chrX7044354170443556+3'-UTR,5'-UTR,intron-Proximal3.416735.22400HepG2DDX3X
chrX7044446470444515+3'-UTR6.1572466.82148HepG2UPF1
chrX7044486970444898+3'-UTR5.5255323.35409HepG2AKAP1
chrX7043507870435140+5'-UTR,intron-Proximal3.105274.75864HepG2DDX3X
chrX7044376270443806+CDS5.856418.16103HepG2PCBP1
chrX7044423470444285+CDS4.2997524.52616HepG2SND1
chrX7044370370443746+CDS4.8260911.93472HepG2RPS3
chrX7044381670443846+CDS3.710855.42514HepG2RPS3
chrX7044407470444141+CDS4.023283.83024HepG2IGF2BP1
chrX7044363970443701+CDS5.6531615.08033HepG2RPS3
chrX7044376370443798+CDS4.307178.09380HepG2RPS3
chrX7044372170443755+CDS3.465425.86870HepG2SND1
chrX7044387070443955+CDS4.5786727.78835HepG2SND1
chrX7044407370444125+CDS3.5804910.16967HepG2SND1
chrX7044418570444241+CDS3.902773.74540HepG2IGF2BP1
chrX7044380670443842+CDS3.954605.97445HepG2PCBP1
chrX7044434170444382+CDS4.771006.60283HepG2RPS3
chrX7044401170444060+CDS4.048955.76695HepG2RBM15
chrX7044415570444234+CDS4.3313422.49749HepG2SND1
chrX7044402470444073+CDS5.3140217.35887HepG2SND1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for GJB1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for GJB1 is not available on ENCORE database.

  • 113 RBPs can affect the levels of GJB1.  








The Knockdown/knockout RNA-Seq assay for GJB1 is not available on ENCORE database.





113 RBPs can affect the gene expression of GJB1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
GJB1ENSG00000169562.9695.504301410.84200-1.0204017.9279015.58330HepG2AATF
GJB1ENSG00000169562.9614.144401988.27340-1.6949047.1942045.44990HepG2ACO1
GJB1ENSG00000169562.9453.189404399.87750-3.27930124.37490121.81840HepG2AKAP1
GJB1ENSG00000169562.92607.174603640.44360-0.481604.863503.83500HepG2ASCC1
GJB1ENSG00000169562.91934.595102243.01250-0.213402.278401.64470HepG2AUH
GJB1ENSG00000169562.91690.317401066.484900.664304.603903.46850HepG2BCLAF1
GJB1ENSG00000169562.91297.013601059.839900.291202.038001.51810HepG2BOP1
GJB1ENSG00000169562.94640.812903458.699700.424004.209903.26800HepG2CIRBP
GJB1ENSG00000169562.9611.64540956.76980-0.645503.801702.89870HepG2CNOT7
GJB1ENSG00000169562.91914.49380972.997500.9764017.4157015.86740HepG2CPSF6
GJB1ENSG00000169562.91364.264701075.819000.342603.760002.56900HepG2YBX3
GJB1ENSG00000169562.9936.421701445.01720-0.625903.481801.89050HepG2CSTF2T
GJB1ENSG00000169562.91324.424701882.06800-0.507008.378607.37520HepG2CELF1
GJB1ENSG00000169562.92627.855902023.367100.377009.067407.84860HepG2DAZAP1
GJB1ENSG00000169562.91216.626001555.46120-0.354502.977402.27620HepG2DDX21
GJB1ENSG00000169562.91775.952501280.905300.471304.928503.22730HepG2DDX47
GJB1ENSG00000169562.9735.332401207.04770-0.715005.227604.20480HepG2DDX55
GJB1ENSG00000169562.93782.059301835.073601.0432022.3307019.92080HepG2DDX5
GJB1ENSG00000169562.92079.423903620.83220-0.800109.970008.87690HepG2DDX6
GJB1ENSG00000169562.91709.287401018.863600.7463011.472509.65490HepG2DHX30
GJB1ENSG00000169562.93051.581301902.159100.6818012.1926010.98360HepG2DKC1
GJB1ENSG00000169562.91578.724301056.360800.5796010.152908.87440HepG2DNAJC21
GJB1ENSG00000169562.91528.591601047.051500.5458012.2953011.02390HepG2DNAJC2
GJB1ENSG00000169562.92163.051001201.208700.8485012.4503010.70100HepG2EEF2
GJB1ENSG00000169562.9964.006101433.13920-0.572104.307402.91350HepG2AGO1
GJB1ENSG00000169562.9500.17150975.00250-0.9630012.1421010.39690HepG2EIF3D
GJB1ENSG00000169562.91243.671403745.02110-1.5904027.9224025.91720HepG2EIF4B
GJB1ENSG00000169562.91614.132902575.34890-0.6740019.3687018.01660HepG2ETF1
GJB1ENSG00000169562.91020.931101482.78910-0.538406.367904.75730HepG2FASTKD2
GJB1ENSG00000169562.9554.306102439.21340-2.137707.282906.09680HepG2FIP1L1
GJB1ENSG00000169562.91509.250501004.575100.587104.478902.89370HepG2FKBP4
GJB1ENSG00000169562.91748.515502697.55170-0.625509.722708.29810HepG2FUBP3
GJB1ENSG00000169562.9960.650901565.38830-0.704403.309602.08550HepG2FUS
GJB1ENSG00000169562.91952.867103881.08540-0.9909017.9337016.34840HepG2FXR1
GJB1ENSG00000169562.91961.774903599.94510-0.8758012.8662011.48620HepG2G3BP1
GJB1ENSG00000169562.92488.546801102.987001.1738020.5832019.00940HepG2GPKOW
GJB1ENSG00000169562.9594.78070885.69130-0.574403.398202.16210HepG2GRSF1
GJB1ENSG00000169562.91523.109101898.04480-0.317503.056102.03500HepG2HDGF
GJB1ENSG00000169562.91842.761701066.481200.7889012.9638011.73490HepG2HNRNPA1
GJB1ENSG00000169562.91539.030701859.68580-0.273002.892901.94020HepG2HNRNPA2B1
GJB1ENSG00000169562.91193.50850828.750800.526103.404101.71080HepG2HNRNPD
GJB1ENSG00000169562.92160.948201122.036000.9454029.2381027.29190HepG2HNRNPF
GJB1ENSG00000169562.91530.374903646.04280-1.2524031.7343029.63850HepG2HNRNPK
GJB1ENSG00000169562.91331.587301843.03600-0.468905.467304.54760HepG2HNRNPL
GJB1ENSG00000169562.93554.042501052.599201.7554026.5164024.89760HepG2HNRNPLL
GJB1ENSG00000169562.91674.695901178.426000.506909.725408.64450HepG2HNRNPU
GJB1ENSG00000169562.93335.980501104.872201.5941027.7140025.71200HepG2IGF2BP1
GJB1ENSG00000169562.9833.022503434.42620-2.0436016.6025014.46760HepG2IGF2BP3
GJB1ENSG00000169562.91400.197801203.722100.218002.674301.95380HepG2ILF2
GJB1ENSG00000169562.91298.90990932.745200.477602.727201.42050HepG2ILF3
GJB1ENSG00000169562.92130.638801817.339300.229402.765101.74720HepG2KIF1C
GJB1ENSG00000169562.9866.480301303.46680-0.589106.848905.10900HepG2LARP7
GJB1ENSG00000169562.95147.996503882.443200.406903.702602.94390HepG2MAGOH
GJB1ENSG00000169562.91866.729203904.07050-1.0645017.6095016.12670HepG2MATR3
GJB1ENSG00000169562.9510.165801020.34930-1.000008.405706.67400HepG2METAP2
GJB1ENSG00000169562.91779.553501073.473900.729105.547804.14800HepG2MTPAP
GJB1ENSG00000169562.92058.828203995.95010-0.9567015.7202014.29380HepG2NCBP2
GJB1ENSG00000169562.91595.21420933.317000.7732010.451509.07410HepG2NSUN2
GJB1ENSG00000169562.9589.27770874.48930-0.569502.777101.88750HepG2PABPC1
GJB1ENSG00000169562.92246.595103558.27220-0.663408.148106.92460HepG2PABPC4
GJB1ENSG00000169562.9524.990701166.43220-1.1517030.9947028.76910HepG2PARN
GJB1ENSG00000169562.92517.994603894.88990-0.6293020.0189018.62750HepG2PCBP1
GJB1ENSG00000169562.91474.262901051.060800.488004.332203.43100HepG2PPIL4
GJB1ENSG00000169562.9693.04130930.64530-0.425303.117702.26490HepG2PRPF8
GJB1ENSG00000169562.91885.698203963.09060-1.0715046.1881044.53650HepG2PTBP1
GJB1ENSG00000169562.92981.909301915.356900.6385011.022209.93920HepG2PUF60
GJB1ENSG00000169562.91046.571402033.33920-0.9582025.2047023.78110HepG2PUM1
GJB1ENSG00000169562.93700.815602025.140300.8697031.7777030.11230HepG2PUS1
GJB1ENSG00000169562.92425.103804292.34980-0.8237024.5688022.96700HepG2QKI
GJB1ENSG00000169562.9259.833701429.34200-2.4597020.9763019.21240HepG2RAVER1
GJB1ENSG00000169562.91508.999702169.46420-0.523708.181806.81150HepG2RBM15
GJB1ENSG00000169562.9846.800502152.50040-1.3459049.6335047.97030HepG2RBM22
GJB1ENSG00000169562.91843.795603895.49840-1.0791031.2035029.12920HepG2RBM25
GJB1ENSG00000169562.91181.243101571.78260-0.412103.392902.28860HepG2RBM27
GJB1ENSG00000169562.92113.955804410.62700-1.0610052.4282050.77120HepG2NELFE
GJB1ENSG00000169562.92117.925204107.74060-0.9557043.6196041.76480HepG2RECQL
GJB1ENSG00000169562.92632.758901208.901801.1228024.8899023.27160HepG2RPLP0
GJB1ENSG00000169562.92130.560001405.008700.600603.614802.53550HepG2RPS10
GJB1ENSG00000169562.9694.03810948.83280-0.451104.181203.44040HepG2RPS19
GJB1ENSG00000169562.92162.50650960.746601.1704015.3342013.51010HepG2RPS3A
GJB1ENSG00000169562.91120.714601479.72840-0.400903.450402.24720HepG2RPS5
GJB1ENSG00000169562.9404.27960920.55230-1.1871012.1703010.70930HepG2RRP9
GJB1ENSG00000169562.91407.641101049.436800.423604.027503.27530HepG2SAFB2
GJB1ENSG00000169562.91553.24500827.554900.908302.692901.36650HepG2SF1
GJB1ENSG00000169562.91289.611502662.84890-1.0460012.4726010.98020HepG2SF3A3
GJB1ENSG00000169562.91746.807801041.875900.7454010.664509.36340HepG2SF3B1
GJB1ENSG00000169562.91628.054504126.27800-1.3417079.5652077.26130HepG2SF3B4
GJB1ENSG00000169562.92997.025801836.740600.7063028.6522026.86530HepG2SLBP
GJB1ENSG00000169562.9791.635101223.81450-0.6285013.6302012.36980HepG2SMN1
GJB1ENSG00000169562.91351.35880739.561800.869602.773101.45980HepG2SNRNP200
GJB1ENSG00000169562.9742.063302431.14410-1.71200102.90850100.97280HepG2SRFBP1
GJB1ENSG00000169562.92046.270004306.86370-1.0736059.2719057.72420HepG2SRSF1
GJB1ENSG00000169562.9718.281601121.03170-0.642204.692003.35600HepG2SRSF3
GJB1ENSG00000169562.91331.875901891.25970-0.505902.683502.06420HepG2SRSF5
GJB1ENSG00000169562.92825.287201102.408101.3576014.9271013.53650HepG2SRSF7
GJB1ENSG00000169562.91124.796203503.79650-1.63930107.31230104.95120HepG2SRSF9
GJB1ENSG00000169562.94168.243502110.763400.9816048.1937046.69830HepG2SSB
GJB1ENSG00000169562.91593.553702150.77740-0.432607.074106.15970HepG2SUCLG1
GJB1ENSG00000169562.92751.478001645.729400.741404.371303.20280HepG2SUPT6H
GJB1ENSG00000169562.91595.524203870.96280-1.2787058.0279055.88450HepG2TAF15
GJB1ENSG00000169562.91750.240601025.909200.770608.728707.54260HepG2TARDBP
GJB1ENSG00000169562.91827.399403557.11480-0.9609026.4223023.88380HepG2TIA1
GJB1ENSG00000169562.91906.121601145.037700.7351014.3229013.34140HepG2TIAL1
GJB1ENSG00000169562.91403.112401155.298600.280303.329102.72300HepG2TRIM56
GJB1ENSG00000169562.92707.570901871.391200.532805.589504.29570HepG2TUFM
GJB1ENSG00000169562.9481.52880709.63790-0.559503.622202.75590HepG2UCHL5
GJB1ENSG00000169562.91389.206502279.97620-0.7148020.4354019.03300HepG2UTP3
GJB1ENSG00000169562.91279.86060860.543300.572603.846302.54740HepG2XPO5
GJB1ENSG00000169562.9663.263201406.45830-1.084406.840504.88380HepG2XRCC5
GJB1ENSG00000169562.9819.846201572.40950-0.939606.207604.66310HepG2XRCC6
GJB1ENSG00000169562.91831.500301182.704000.630805.700404.67310HepG2XRN2
GJB1ENSG00000169562.91797.221801349.586600.413207.864406.82760HepG2ZC3H8
GJB1ENSG00000169562.91938.773402597.24300-0.4218010.741809.83970HepG2ZNF622
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for GJB1 is not available on ENCORE database.





1 RBPs can affect the splicing of GJB1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEGJB1ENSG00000169562.9chrX+7044243370442616704351087043514070443541704438100.070000.000220.05383includedHepG2EIF3D

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for GJB1 is not avaliable on ENCORE database.