FKBP3

General Information

Gene Name       : FKBP3
Gene ID             : ENSG00000100442.10
Essential Gene : No

Functions

Localization

Domains (AlphaFold: FKBP3)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878FKBP3ENSG00000100442.1093.8496.1494.99ENCSR000AEF
HepG2FKBP3ENSG00000100442.1065.63140.12102.88ENCSR985KAT
K562FKBP3ENSG00000100442.1063.5557.4860.52ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  
  GeneName    Antibody_DCC_ID    Product_ID    Lot_ID    Phosphate    HepG2 Primary Validation    K562 Primary Validation    HepG2 Secondary Validation    K562 Secondary Validation  
FKBP3A302-600A1BGHcLV41-75, Submitted, ENCORE2BGKcLV40-55, Submitted, ENCORE2


  KD RNA-Seq  
  GeneName    Cell_Line    Method    Exp_ID    Control_ID    Sample_reps    Control_reps    KD%    Status    Project    Note  
FKBP3K562CRISPRFKBP3-BGKcLV40-55,FKBP3-BGKcLV40-56NT-BGKcLV40-1,NT-BGKcLV40-259.2,67.7SubmittingENCORE2
FKBP3HepG2CRISPRFKBP3-BGHcLV41-75,FKBP3-BGHcLV41-76NT-BGHcLV41-1,NT-BGHcLV41-276.3,68.0SubmittingENCORE2


  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela
FKBP3Product_ID: A302-600A
Lot_ID: 1
Source: Bethyl Labs
Target Name: FKBP3-human		 FKBP3-HEPG2-CRISPR-A302-600A.png<br>Caption: Western blot following CRISPR against FKBP3 in HepG2 whole cell lysate using FKBP3 specific antibody. Lane 1 is a ladder, lane 2 is HepG2 non-targeting control knockdown, lane 3 and 4 are two different CRISPR against FKBP3. FKBP3 protein appears as the green arrow, Beta-actin serves as a control and appears in red arrow.
 FKBP3-K562-CRISPR-A302-600A.png<br>Caption: Western blot following CRISPR against FKBP3 in K562 whole cell lysate using FKBP3 specific antibody. Lane 1 is a ladder, lane 2 is K562 non-targeting control knockdown, lane 3 and 4 are two different CRISPR against FKBP3. FKBP3 protein appears as the green arrow, Beta-actin serves as a control and appears in red arrow.








RNA Targets

  • eCLIP assay for FKBP3 is not avaliable on ENCORE database.



Proteins bound to RNA
  • FKBP3 RNA is bound by 13 proteins.  







eCLIP assay for FKBP3 is not avaliable on ENCORE database.





13 proteins are bound to FKBP3 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr144559078845590824-3'-UTR,CDS,intron-Distal,intron-Proximal4.064133.39686HepG2G3BP1
chr144558526945585332-3'-UTR,intron-Distal3.628535.53855K562YBX3
chr144558518945585313-3'-UTR,intron-Distal5.081297.83850HepG2SUB1
chr144559076245590794-3'-UTR,CDS,intron-Distal,intron-Proximal3.469145.76104HepG2BCLAF1
chr144559011345590156-3'-UTR,CDS,intron-Distal5.6390711.50624HepG2BCLAF1
chr144559080745590823-3'-UTR,CDS,intron-Distal5.130116.58593HepG2BCLAF1
chr144558513945585211-3'-UTR,intron-Distal3.590537.82982K562PUM2
chr144558516445585214-3'-UTR,intron-Distal3.985565.19325HepG2LARP4
chr144559899645599058-5'-UTR,CDS,intron-Distal,intron-Proximal3.050545.88048HepG2G3BP1
chr144560359245603669-5'-UTR,CDS,intron-Distal3.382755.57370HepG2DDX3X
chr144559899545599065-5'-UTR,CDS,intron-Distal,intron-Proximal3.885485.58370HepG2PPIG
chr144560357445603678-5'-UTR,CDS,intron-Distal3.957716.72914HepG2SRSF1
chr144560358945603672-5'-UTR,CDS,intron-Distal3.542809.27595K562DDX3X
chr144559992745599980-5'-UTR,CDS,intron-Distal3.034555.99957HepG2BCLAF1
chr144559906345599100-5'-UTR,CDS,intron-Distal3.358256.09950HepG2BCLAF1
chr144559899545599063-5'-UTR,CDS,intron-Distal,intron-Proximal5.3953620.96897HepG2BCLAF1
chr144559899645599063-5'-UTR,CDS,intron-Distal,intron-Proximal3.027035.86433K562UCHL5
chr144560355145603581-CDS,intron-Distal,intron-Proximal3.063403.95805K562DDX3X
chr144558722945587292-CDS,intron-Distal,intron-Proximal3.512366.51082HepG2PPIG
chr144558728345587329-CDS,intron-Distal,intron-Proximal3.013065.51984K562UCHL5
chr144559008945590113-CDS,intron-Distal,intron-Proximal4.694759.74753HepG2BCLAF1
chr144558723345587267-CDS,intron-Distal5.7666212.56307HepG2BCLAF1
chr144558726745587329-CDS,intron-Distal,intron-Proximal4.1955119.86037HepG2BCLAF1
chr144558723245587276-CDS,intron-Distal3.202904.79633HepG2G3BP1
chr144560312445603242-intron-Distal3.879683.48162HepG2TAF15
chr144559681445596865-intron-Distal4.046053.30440HepG2QKI
chr144560316045603214-intron-Distal4.616616.34455HepG2PRPF4
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for FKBP3 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for FKBP3 is not available on ENCORE database.

  • 114 RBPs can affect the levels of FKBP3.  








The Knockdown/knockout RNA-Seq assay for FKBP3 is not available on ENCORE database.





114 RBPs can affect the gene expression of FKBP3 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
FKBP3ENSG00000100442.61428.115101632.02730-0.192601.957901.42980HepG2ACO1
FKBP3ENSG00000100442.61744.941102218.02730-0.346102.571401.81230HepG2ASCC1
FKBP3ENSG00000100442.62238.319802567.06950-0.197702.160301.54000HepG2AUH
FKBP3ENSG00000100442.6900.085101424.04660-0.661908.225607.25990HepG2BOP1
FKBP3ENSG00000100442.6992.692101249.84020-0.332302.600601.40960HepG2BUD13
FKBP3ENSG00000100442.61533.478402442.99420-0.671804.861503.55550HepG2CCAR1
FKBP3ENSG00000100442.61691.638002107.27950-0.317002.284501.57730HepG2CIRBP
FKBP3ENSG00000100442.61331.474101631.62860-0.293304.220403.43220HepG2CKAP4
FKBP3ENSG00000100442.61066.151401307.35620-0.294201.948601.36070HepG2CPSF6
FKBP3ENSG00000100442.62208.492402705.73590-0.293005.450404.45730HepG2DAZAP1
FKBP3ENSG00000100442.6923.459401443.63810-0.644607.756206.67830HepG2DDX21
FKBP3ENSG00000100442.6997.241801408.10590-0.497709.960608.81550HepG2DNAJC2
FKBP3ENSG00000100442.61561.487902120.54330-0.441503.728203.04700HepG2EIF2S1
FKBP3ENSG00000100442.61495.656902343.44300-0.647906.384105.41430HepG2EIF4A3
FKBP3ENSG00000100442.6932.424502281.68320-1.2910017.7353016.09650HepG2EIF4B
FKBP3ENSG00000100442.61797.157902557.00320-0.508703.636802.71030HepG2EIF4G2
FKBP3ENSG00000100442.61830.846901445.063700.341302.743701.65540HepG2ESF1
FKBP3ENSG00000100442.62323.740102947.35000-0.343005.622904.81590HepG2ETF1
FKBP3ENSG00000100442.61965.867901594.743200.301702.289101.53030HepG2EWSR1
FKBP3ENSG00000100442.61661.458802364.45580-0.509104.966904.06000HepG2FXR1
FKBP3ENSG00000100442.61687.973102193.36890-0.377902.710002.05090HepG2G3BP1
FKBP3ENSG00000100442.61127.250801501.18490-0.413302.924201.87590HepG2GNB2L1
FKBP3ENSG00000100442.61235.970001558.09220-0.334104.416703.20220HepG2HDGF
FKBP3ENSG00000100442.61139.466101434.34910-0.332002.778602.13050HepG2HNRNPA1
FKBP3ENSG00000100442.62118.095402486.58640-0.231402.745501.81360HepG2HNRNPA2B1
FKBP3ENSG00000100442.61265.200701595.41920-0.334602.726402.03760HepG2HNRNPC
FKBP3ENSG00000100442.61303.476501588.13440-0.285003.344902.56170HepG2HNRNPF
FKBP3ENSG00000100442.61599.781102221.00930-0.473304.913604.00390HepG2HNRNPK
FKBP3ENSG00000100442.61037.259001414.29960-0.447303.686902.97080HepG2HNRNPLL
FKBP3ENSG00000100442.61183.308101584.87340-0.421506.790505.87890HepG2HNRNPU
FKBP3ENSG00000100442.61243.409401563.85610-0.330803.357202.56640HepG2IGF2BP1
FKBP3ENSG00000100442.61364.458102229.50780-0.708408.842707.71160HepG2IGF2BP2
FKBP3ENSG00000100442.61231.786201491.85020-0.276403.688002.51170HepG2KIF1C
FKBP3ENSG00000100442.61712.368402578.29570-0.590404.360203.31160HepG2LARP4
FKBP3ENSG00000100442.61516.499802365.28130-0.641307.263706.21540HepG2MAGOH
FKBP3ENSG00000100442.61856.331402378.51630-0.357602.401701.81150HepG2MATR3
FKBP3ENSG00000100442.61113.187801363.29580-0.292402.263801.52930HepG2MSI2
FKBP3ENSG00000100442.61841.887302434.54100-0.402503.116802.44710HepG2NCBP2
FKBP3ENSG00000100442.62288.133902682.99520-0.229702.304001.60810HepG2NOL12
FKBP3ENSG00000100442.6926.158701453.71860-0.650402.575301.52460HepG2NONO
FKBP3ENSG00000100442.61305.901102168.10540-0.731408.967207.68640HepG2PABPC4
FKBP3ENSG00000100442.61011.583401568.78960-0.6330011.447309.91750HepG2PARN
FKBP3ENSG00000100442.61537.174002241.94900-0.5445011.3724010.27820HepG2PCBP1
FKBP3ENSG00000100442.61028.450401413.58550-0.458906.332505.24980HepG2PPIL4
FKBP3ENSG00000100442.6924.834001279.18230-0.468006.810305.65880HepG2PRPF4
FKBP3ENSG00000100442.61679.159102281.23200-0.442107.772406.94860HepG2PTBP1
FKBP3ENSG00000100442.61828.423202561.11780-0.486206.377205.52180HepG2PUF60
FKBP3ENSG00000100442.62068.690002718.69740-0.3942010.039009.05700HepG2PUM1
FKBP3ENSG00000100442.61609.198102716.73780-0.7555016.9631015.39190HepG2PUM2
FKBP3ENSG00000100442.61928.799702470.70510-0.357204.680403.89960HepG2QKI
FKBP3ENSG00000100442.61527.482902463.43700-0.6895011.8490010.93140HepG2RBM22
FKBP3ENSG00000100442.61772.933302242.29550-0.338803.471202.72260HepG2RBM25
FKBP3ENSG00000100442.61285.164001773.35900-0.464504.106702.88060HepG2RBM27
FKBP3ENSG00000100442.61898.734302364.51430-0.316504.802504.01970HepG2RECQL
FKBP3ENSG00000100442.6664.958701194.31770-0.8449013.1696011.95600HepG2RPS19
FKBP3ENSG00000100442.61096.646201411.41690-0.364005.336804.49500HepG2SAFB2
FKBP3ENSG00000100442.6828.650401198.76290-0.532704.641603.43940HepG2SERBP1
FKBP3ENSG00000100442.6727.091301725.56440-1.246904.584202.73750HepG2SF1
FKBP3ENSG00000100442.61034.331001772.28760-0.776906.517305.45720HepG2SF3A3
FKBP3ENSG00000100442.61110.532501399.88330-0.334102.488001.81650HepG2SF3B1
FKBP3ENSG00000100442.61228.687902375.11970-0.9509033.2703031.62630HepG2SF3B4
FKBP3ENSG00000100442.62105.278702455.62610-0.222102.102301.47660HepG2SLBP
FKBP3ENSG00000100442.61376.853701645.97950-0.257602.672702.03740HepG2SMN1
FKBP3ENSG00000100442.61274.558801684.02220-0.401902.305501.44010HepG2SMNDC1
FKBP3ENSG00000100442.62431.290402782.35740-0.194602.313301.84180HepG2SRFBP1
FKBP3ENSG00000100442.62175.590602479.08510-0.188402.210201.77470HepG2SRSF1
FKBP3ENSG00000100442.61788.023302528.68020-0.5000010.982109.84750HepG2SRSF5
FKBP3ENSG00000100442.61477.650502016.84580-0.448808.978108.08490HepG2SRSF9
FKBP3ENSG00000100442.62442.782202875.84930-0.235503.778403.07160HepG2SUCLG1
FKBP3ENSG00000100442.61092.332501558.55290-0.512803.434901.94540HepG2SUGP2
FKBP3ENSG00000100442.6924.657501137.43170-0.298802.183501.34290HepG2SUPT6H
FKBP3ENSG00000100442.61935.362002228.22740-0.203301.952801.46770HepG2TAF15
FKBP3ENSG00000100442.6683.234401378.47630-1.0126016.3859014.87600HepG2TARDBP
FKBP3ENSG00000100442.61542.744002047.51270-0.408404.937703.83080HepG2TIA1
FKBP3ENSG00000100442.61013.560601540.10950-0.603609.476908.64860HepG2TIAL1
FKBP3ENSG00000100442.6926.409701553.76010-0.7460018.6550017.35980HepG2TRIM56
FKBP3ENSG00000100442.62004.771402502.03470-0.319702.267701.48240HepG2TUFM
FKBP3ENSG00000100442.61030.009501794.12510-0.800602.189401.32380HepG2U2AF2
FKBP3ENSG00000100442.62034.525102648.31910-0.380402.682101.85840HepG2UBE2L3
FKBP3ENSG00000100442.6673.98710931.45590-0.466802.775602.01480HepG2UCHL5
FKBP3ENSG00000100442.61111.809101571.74930-0.499509.280208.13190HepG2UPF1
FKBP3ENSG00000100442.61024.889301517.46040-0.5662010.797509.73920HepG2UTP3
FKBP3ENSG00000100442.61917.053501552.004200.304702.615101.91030HepG2XRN2
FKBP3ENSG00000100442.6856.128001728.62170-1.0137040.0651038.61740HepG2ZNF622
FKBP3ENSG00000100442.61270.832401856.41240-0.546706.136404.32140K562ABCF1
FKBP3ENSG00000100442.61655.712301320.495200.326304.093503.42740K562AGGF1
FKBP3ENSG00000100442.63150.645702487.541000.340803.235001.89270K562APOBEC3C
FKBP3ENSG00000100442.6926.809002338.68040-1.3354033.1462031.31650K562AQR
FKBP3ENSG00000100442.6793.626101042.77470-0.393903.912302.75630K562BCLAF1
FKBP3ENSG00000100442.6624.708101052.51690-0.752607.049505.63800K562BOP1
FKBP3ENSG00000100442.6858.127101293.06860-0.591505.436903.36990K562BUD13
FKBP3ENSG00000100442.6266.23650433.53340-0.703404.478103.07420K562CCAR1
FKBP3ENSG00000100442.6951.933101394.40010-0.550703.413201.78670K562CKAP4
FKBP3ENSG00000100442.6689.967001119.17660-0.697806.593505.37780K562CPSF6
FKBP3ENSG00000100442.61472.612601893.52320-0.362705.202804.34830K562DDX47
FKBP3ENSG00000100442.6354.32280485.29330-0.453802.668301.36600K562DHX30
FKBP3ENSG00000100442.61851.916201478.645900.324603.784402.73700K562DKC1
FKBP3ENSG00000100442.61390.154701635.36980-0.234402.251201.59270K562EIF2S2
FKBP3ENSG00000100442.6649.70540909.02630-0.484504.367703.33790K562EIF4A3
FKBP3ENSG00000100442.6570.62010818.60870-0.520605.927604.12730K562EIF4B
FKBP3ENSG00000100442.62245.664602819.10250-0.328104.091202.95330K562EIF4G2
FKBP3ENSG00000100442.6579.04130783.85640-0.436902.782001.51250K562EXOSC5
FKBP3ENSG00000100442.6839.071401138.64040-0.440402.765201.91130K562FMR1
FKBP3ENSG00000100442.6677.81940965.05910-0.509703.947502.83980K562FTO
FKBP3ENSG00000100442.61402.482301046.934400.421702.535601.86350K562G3BP2
FKBP3ENSG00000100442.6985.401101210.76410-0.297102.731501.59920K562GLRX3
FKBP3ENSG00000100442.6662.354901068.57760-0.690006.477105.26610K562GPKOW
FKBP3ENSG00000100442.6515.889301010.32590-0.9697015.0219013.71670K562HNRNPC
FKBP3ENSG00000100442.6560.26810902.18960-0.687307.771405.78280K562HNRNPF
FKBP3ENSG00000100442.61373.168401711.18620-0.317502.819301.75130K562HNRNPL
FKBP3ENSG00000100442.61413.812401097.592000.365102.389801.52750K562HNRNPM
FKBP3ENSG00000100442.6918.157701235.28220-0.428002.722401.70690K562IGF2BP2
FKBP3ENSG00000100442.6568.02880912.32880-0.683605.003103.70340K562KRR1
FKBP3ENSG00000100442.6952.075001298.59080-0.447804.526403.44450K562MAGOH
FKBP3ENSG00000100442.6762.025801043.03440-0.452903.016402.10030K562METAP2
FKBP3ENSG00000100442.6994.881501414.37640-0.5076010.589509.26000K562NSUN2
FKBP3ENSG00000100442.6726.69590994.71210-0.452903.141201.59240K562NUSAP1
FKBP3ENSG00000100442.61030.42220806.991500.352502.376101.67920K562PRPF8
FKBP3ENSG00000100442.6651.10700905.85390-0.476403.506702.47110K562PSIP1
FKBP3ENSG00000100442.62649.359303205.59190-0.274903.326202.27260K562PUM2
FKBP3ENSG00000100442.62102.010001362.767600.625107.304906.46920K562PUS1
FKBP3ENSG00000100442.61573.747901327.713800.245202.070001.54340K562RBM15
FKBP3ENSG00000100442.6768.468101209.95330-0.654907.848906.33970K562RBM22
FKBP3ENSG00000100442.6630.19460826.43040-0.391103.124102.06300K562RCC2
FKBP3ENSG00000100442.6586.46010822.05020-0.487203.022302.16830K562RPS19
FKBP3ENSG00000100442.6683.278001192.90050-0.803903.227601.90190K562SF1
FKBP3ENSG00000100442.6743.224101395.62320-0.9090021.2905019.20570K562SF3A3
FKBP3ENSG00000100442.6682.449301016.11180-0.574304.548803.28550K562SF3B1
FKBP3ENSG00000100442.6655.836501088.95540-0.7315011.255809.46470K562SF3B4
FKBP3ENSG00000100442.6519.77950783.43850-0.591905.191003.65660K562SRFBP1
FKBP3ENSG00000100442.61107.169001429.84560-0.369005.460904.20080K562SRPK2
FKBP3ENSG00000100442.6932.894701236.78330-0.406803.885803.05380K562SRSF1
FKBP3ENSG00000100442.6564.07340781.41110-0.470202.952901.90130K562SUPV3L1
FKBP3ENSG00000100442.6971.57130767.081400.340802.849102.01600K562SYNCRIP
FKBP3ENSG00000100442.6995.378401251.79190-0.330702.298001.65010K562TARDBP
FKBP3ENSG00000100442.6936.477501207.47200-0.366703.264702.36520K562TIA1
FKBP3ENSG00000100442.6601.42580871.28530-0.534804.097102.94080K562TIAL1
FKBP3ENSG00000100442.6520.28880925.57900-0.8310010.090908.02190K562TRIM56
FKBP3ENSG00000100442.62816.075303467.88370-0.300402.766301.36590K562UBE2L3
FKBP3ENSG00000100442.61128.771901499.69300-0.409906.313805.28100K562UPF1
FKBP3ENSG00000100442.6977.933901283.24040-0.392003.738702.72110K562WDR3
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for FKBP3 is not available on ENCORE database.





2 RBPs can affect the splicing of FKBP3 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
A3SSFKBP3ENSG00000100442.6chr14-455872304558742945587230455873524559008945590157-0.593000.009210.04928shorterK562AQR
MXEFKBP3ENSG00000100442.6chr14-4559899645599104455999014560000345590687455908234560355145603732-0.102000.004640.033682includedK562AQR
MXEFKBP3ENSG00000100442.6chr14-4559899645599104455999014560000345590687455908234560355145603732-0.129000.000010.002652includedK562PUM1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for FKBP3 is not avaliable on ENCORE database.