CYB5B

General Information

Gene Name       : CYB5B
Gene ID             : ENSG00000103018.16
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: CYB5B)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878CYB5BENSG00000103018.16223.95207.73215.84ENCSR000AEF
HepG2CYB5BENSG00000103018.16216.48249.95233.21ENCSR985KAT
K562CYB5BENSG00000103018.16120.84133.13126.98ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for CYB5B is not avaliable on ENCORE database.



Proteins bound to RNA
  • CYB5B RNA is bound by 26 proteins.  







eCLIP assay for CYB5B is not avaliable on ENCORE database.





26 proteins are bound to CYB5B RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr166949665269496715+3'-UTR3.618497.83818K562IGF2BP1
chr166949715069497200+3'-UTR3.6770115.06487K562UPF1
chr166949707869497150+3'-UTR3.0374012.04023K562UPF1
chr166949647669496559+3'-UTR3.535947.02736K562PABPC4
chr166949715669497189+3'-UTR3.402697.54493HepG2AKAP1
chr166949708769497135+3'-UTR4.7663521.83583HepG2UPF1
chr166949702269497059+3'-UTR4.156616.62084HepG2AKAP1
chr166949656369496621+3'-UTR3.946445.11392HepG2IGF2BP3
chr166949643669496517+3'-UTR3.2817918.45373HepG2LARP4
chr166949648769496568+3'-UTR3.196009.48709HepG2AKAP1
chr166949750369497557+3'-UTR3.608969.29857HepG2UPF1
chr166949709969497156+3'-UTR3.8728411.63263K562FAM120A
chr166949716169497208+3'-UTR4.7631215.10596K562FAM120A
chr166949650369496584+3'-UTR4.6464722.63930HepG2UPF1
chr166949685269496940+3'-UTR3.3881262.97551K562UPF1
chr166949763569497680+3'-UTR5.0548917.90521K562PUM2
chr166949701669497031+3'-UTR4.4773812.41920K562UPF1
chr166949684769496921+3'-UTR3.9875933.22751K562FAM120A
chr166949636969496430+3'-UTR,CDS3.987266.98930HepG2U2AF2
chr166949738369497435+3'-UTR6.1735414.48846K562UPF1
chr166949722569497282+3'-UTR3.602289.28743HepG2FAM120A
chr166949684869496921+3'-UTR3.1944623.70692HepG2AKAP1
chr166949651169496571+3'-UTR3.7143711.08187HepG2GRWD1
chr166949656969496637+3'-UTR3.845115.68440K562IGF2BP1
chr166949749769497579+3'-UTR3.2878710.10933K562FAM120A
chr166949702669497065+3'-UTR5.448549.71889K562FAM120A
chr166949687169496948+3'-UTR5.06394400.00000HepG2UPF1
chr166949657169496633+3'-UTR3.138676.81934HepG2GRWD1
chr166949652369496569+3'-UTR3.044504.67716K562IGF2BP1
chr166949684069496871+3'-UTR5.0262778.13346HepG2UPF1
chr166949723969497322+3'-UTR5.5277421.70604HepG2UPF1
chr166949713569497197+3'-UTR5.3988739.58639HepG2UPF1
chr166949645269496511+3'-UTR3.127826.81934HepG2GRWD1
chr166949703169497057+3'-UTR4.7384315.51277K562UPF1
chr166949715769497218+3'-UTR3.7788419.17764HepG2FAM120A
chr166949662169496674+3'-UTR4.330223.08588HepG2IGF2BP3
chr166949671569496777+3'-UTR5.3212311.48733K562IGF2BP1
chr166948109169481183+CDS,intron-Distal,intron-Proximal3.037013.06300HepG2UCHL5
chr166948110069481185+CDS,intron-Distal,intron-Proximal4.2074114.57544HepG2GRWD1
chr166948201769482027+CDS,intron-Distal,intron-Proximal3.594273.60157HepG2GRWD1
chr166948101969481092+CDS,intron-Distal,intron-Proximal3.786796.23149HepG2AQR
chr166948202769482050+CDS,intron-Distal,intron-Proximal4.446213.31827HepG2GRWD1
chr166948110869481173+CDS,intron-Distal3.305207.63733HepG2PPIG
chr166949631069496369+CDS,intron-Proximal3.8743810.58235HepG2U2AF2
chr166949298469493085+CDS,intron-Distal,intron-Proximal3.4405410.62619HepG2U2AF2
chr166948201369482078+CDS,intron-Distal,intron-Proximal3.333828.28669HepG2PPIG
chr166949629969496350+CDS,intron-Proximal5.050935.90023K562SF3B4
chr166948104969481100+CDS,intron-Distal,intron-Proximal4.368769.94686HepG2GRWD1
chr166945871669458881+CDS,intron-Distal,intron-Proximal3.502797.99229HepG2AQR
chr166948105069481093+CDS,intron-Distal,intron-Proximal3.192524.44431HepG2G3BP1
chr166949298869493085+CDS,intron-Distal,intron-Proximal3.250584.20273HepG2PRPF8
chr166949298869493068+CDS,intron-Distal,intron-Proximal4.181188.13631HepG2EFTUD2
chr166945871469458769+CDS,intron-Proximal3.408213.90917HepG2PRPF4
chr166949219869492281+intron-Distal4.135604.93238K562QKI
chr166948297069483042+intron-Distal5.3428814.62925HepG2QKI
chr166948514669485204+intron-Distal5.3434732.34998HepG2QKI
chr166945891469458992+intron-Distal4.117364.57350K562RBFOX2
chr166948931669489330+intron-Distal3.9618510.99774HepG2HNRNPC
chr166946387369463963+intron-Distal4.313893.86368HepG2HNRNPM
chr166946293169463052+intron-Distal3.566386.91468HepG2HNRNPM
chr166945889869458983+intron-Distal5.248777.61488HepG2EFTUD2
chr166948242669482486+intron-Distal3.365935.40388HepG2U2AF2
chr166945876769458879+intron-Distal,intron-Proximal4.2120816.87667HepG2RBFOX2
chr166948501569485031+intron-Distal6.6720227.28969HepG2QKI
chr166948443469484480+intron-Distal3.783256.26907HepG2SUGP2
chr166945995269460051+intron-Distal5.9107112.57135HepG2QKI
chr166948249469482554+intron-Distal4.8632024.18603HepG2U2AF2
chr166948521769485244+intron-Distal4.007648.61413HepG2QKI
chr166947163869471756+intron-Distal3.105106.30194HepG2QKI
chr166948249869482554+intron-Distal3.800135.75179HepG2U2AF1
chr166945883969458878+intron-Distal,intron-Proximal3.397254.98844HepG2FAM120A
chr166948305869483119+intron-Distal3.3027712.29132HepG2QKI
chr166948506369485130+intron-Distal5.7134954.28028HepG2QKI
chr166946413369464192+intron-Distal3.253014.48901HepG2HNRNPC
chr166946185169461893+intron-Distal4.127583.18711HepG2ILF3
chr166945889269458968+intron-Distal3.828865.38982HepG2PRPF4
chr166948503169485063+intron-Distal6.9557733.43709HepG2QKI
chr166945876969458889+intron-Distal,intron-Proximal5.331499.69835HepG2PRPF4
chr166948289669482970+intron-Distal5.4098130.35665HepG2QKI
chr166948933069489365+intron-Distal4.0469612.53715HepG2HNRNPC
chr166945891669458970+intron-Distal3.991656.10298HepG2GTF2F1
chr166948492269484971+intron-Distal3.9362710.98076HepG2QKI
chr166949219369492303+intron-Distal4.5872818.50074HepG2QKI
chr166948430169484336+intron-Distal3.643825.79523HepG2SUGP2
chr166945887969458983+intron-Distal5.4960222.70939HepG2RBFOX2
chr166945880569458879+intron-Distal,intron-Proximal4.886926.11395HepG2GTF2F1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for CYB5B is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for CYB5B is not available on ENCORE database.

  • 111 RBPs can affect the levels of CYB5B.  








The Knockdown/knockout RNA-Seq assay for CYB5B is not available on ENCORE database.





111 RBPs can affect the gene expression of CYB5B :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
CYB5BENSG00000103018.123335.988804114.42830-0.302602.173601.33550HepG2ABCF1
CYB5BENSG00000103018.1210700.793806929.618300.626807.086606.27860HepG2AKAP1
CYB5BENSG00000103018.127197.216305733.739900.327902.710401.93330HepG2ASCC1
CYB5BENSG00000103018.129999.735306542.653200.6119022.7896021.16550HepG2AUH
CYB5BENSG00000103018.123835.798204894.45250-0.351602.390801.52110HepG2BCCIP
CYB5BENSG00000103018.126054.652004252.964300.509505.416904.20000HepG2BCLAF1
CYB5BENSG00000103018.124544.871503475.462800.386905.428404.39520HepG2CALR
CYB5BENSG00000103018.123280.623204629.84100-0.4970017.4602016.10200HepG2CKAP4
CYB5BENSG00000103018.124451.327002369.272000.909708.431307.11680HepG2CNOT7
CYB5BENSG00000103018.123258.139803923.31530-0.268003.413502.28320HepG2YBX3
CYB5BENSG00000103018.127411.662106122.844500.275504.276803.50920HepG2CELF1
CYB5BENSG00000103018.125253.420806583.50160-0.325609.117207.89490HepG2DAZAP1
CYB5BENSG00000103018.123156.049104282.93070-0.4405012.4759010.97260HepG2DDX19B
CYB5BENSG00000103018.122976.198203680.39630-0.306402.942902.24570HepG2DDX21
CYB5BENSG00000103018.125039.899603078.865200.710904.680903.41940HepG2DDX59
CYB5BENSG00000103018.125268.020704430.556500.249703.999203.21420HepG2DKC1
CYB5BENSG00000103018.123322.464303852.46320-0.213502.415901.75350HepG2DNAJC21
CYB5BENSG00000103018.124273.742605481.80540-0.359203.017702.39940HepG2EIF2S1
CYB5BENSG00000103018.127531.881206058.191000.314002.118701.55630HepG2EIF4A3
CYB5BENSG00000103018.125304.502006495.07970-0.292105.440604.33280HepG2EIF4G1
CYB5BENSG00000103018.124920.950506221.86150-0.338403.273602.39150HepG2EIF4G2
CYB5BENSG00000103018.122908.601503564.27840-0.293302.395701.37790HepG2ESF1
CYB5BENSG00000103018.124559.965407511.51570-0.7201022.2157020.79110HepG2ETF1
CYB5BENSG00000103018.122319.333303504.38580-0.595509.304707.91090HepG2FUBP3
CYB5BENSG00000103018.123268.523304112.58880-0.331402.423501.47520HepG2GNB2L1
CYB5BENSG00000103018.123851.792603073.426000.325602.326901.73700HepG2GPKOW
CYB5BENSG00000103018.123088.777303889.36980-0.332503.451202.73940HepG2HNRNPA1
CYB5BENSG00000103018.123383.625704326.17520-0.354503.810803.00780HepG2HNRNPC
CYB5BENSG00000103018.123869.535604510.88930-0.221303.067102.31460HepG2HNRNPF
CYB5BENSG00000103018.123597.965605740.84460-0.6741010.990609.68070HepG2HNRNPK
CYB5BENSG00000103018.125119.228805997.04800-0.228304.025103.22420HepG2HNRNPL
CYB5BENSG00000103018.124904.062602933.029300.7415011.7868010.60320HepG2HNRNPLL
CYB5BENSG00000103018.124404.521402813.609700.646506.294404.46380HepG2HSPD1
CYB5BENSG00000103018.1210680.199305763.536700.8898016.7145015.22240HepG2IGF2BP2
CYB5BENSG00000103018.124110.294105796.97240-0.496103.854902.65170HepG2KHSRP
CYB5BENSG00000103018.123360.927304233.21300-0.332908.288406.59810HepG2KIF1C
CYB5BENSG00000103018.128130.965506114.133600.411203.887203.11100HepG2MAGOH
CYB5BENSG00000103018.124995.384006293.31900-0.333202.519801.91390HepG2NCBP2
CYB5BENSG00000103018.123147.266906528.18980-1.0526040.8679038.31780HepG2NOL12
CYB5BENSG00000103018.126334.761204418.699200.519602.781001.68430HepG2NONO
CYB5BENSG00000103018.123418.682302165.331800.658804.136503.03490HepG2PABPC1
CYB5BENSG00000103018.124382.638205604.88980-0.354902.850402.11870HepG2PABPC4
CYB5BENSG00000103018.123067.748504253.90090-0.4716011.496909.96270HepG2PARN
CYB5BENSG00000103018.122830.022803833.09900-0.437708.121506.90700HepG2PPIL4
CYB5BENSG00000103018.129242.870705807.043600.6704026.1008024.75070HepG2PTBP1
CYB5BENSG00000103018.128401.224806231.744800.430906.050605.21370HepG2PUF60
CYB5BENSG00000103018.125581.635306615.29120-0.245105.818905.02310HepG2PUM1
CYB5BENSG00000103018.124372.076206610.44730-0.5964013.3366011.93120HepG2PUM2
CYB5BENSG00000103018.129211.864804716.931500.9655063.4803061.35350HepG2PUS1
CYB5BENSG00000103018.125289.561306289.69990-0.249803.290902.61770HepG2QKI
CYB5BENSG00000103018.125532.149906278.30510-0.182501.797101.35610HepG2RBM22
CYB5BENSG00000103018.127340.244305708.107300.362704.517503.67280HepG2RBM25
CYB5BENSG00000103018.125031.008203945.158800.350702.732101.67950HepG2RCC2
CYB5BENSG00000103018.124394.428306462.88800-0.5565012.8842011.87580HepG2NELFE
CYB5BENSG00000103018.124071.836006018.92820-0.5638012.6289011.45740HepG2RECQL
CYB5BENSG00000103018.123852.794904859.34510-0.334903.349002.60770HepG2RPLP0
CYB5BENSG00000103018.121830.205202581.15380-0.496006.706305.79570HepG2RPS19
CYB5BENSG00000103018.123277.972702378.546400.462603.146202.29470HepG2RPS3A
CYB5BENSG00000103018.122556.632503827.19830-0.5820020.0875018.57390HepG2SAFB2
CYB5BENSG00000103018.122031.933802903.10480-0.514706.286305.25850HepG2SF3B1
CYB5BENSG00000103018.122325.732303844.97300-0.725303.217001.48360HepG2SLTM
CYB5BENSG00000103018.124927.469604463.189500.142702.177301.59590HepG2SMN1
CYB5BENSG00000103018.122689.892104018.75490-0.579204.622703.35550HepG2SMNDC1
CYB5BENSG00000103018.125438.687607091.23460-0.382808.018007.28750HepG2SRFBP1
CYB5BENSG00000103018.128562.733406310.874300.440107.508206.81810HepG2SRSF1
CYB5BENSG00000103018.123630.714006152.96290-0.7610031.8052030.01160HepG2SRSF5
CYB5BENSG00000103018.123407.428205134.07620-0.5914014.0237012.95290HepG2SRSF9
CYB5BENSG00000103018.129757.818106157.080200.6642016.9685015.92370HepG2SSB
CYB5BENSG00000103018.124337.464705671.95650-0.387007.338606.50050HepG2TAF15
CYB5BENSG00000103018.121455.597702858.86350-0.9738019.4212017.82300HepG2TARDBP
CYB5BENSG00000103018.125118.695102754.015800.894105.237703.80680HepG2TBRG4
CYB5BENSG00000103018.123280.147005212.28950-0.6682014.5795012.70060HepG2TIA1
CYB5BENSG00000103018.124977.324104176.008600.253102.705702.20970HepG2TIAL1
CYB5BENSG00000103018.125350.607203554.128100.590108.328507.23710HepG2U2AF1
CYB5BENSG00000103018.125174.938904288.467000.271005.139804.36630HepG2UTP3
CYB5BENSG00000103018.123706.887703151.440700.234104.031903.24530HepG2ZC3H8
CYB5BENSG00000103018.126009.019304885.224000.298608.107507.29930HepG2ZNF622
CYB5BENSG00000103018.122036.543201568.797100.376403.606102.23880K562AARS
CYB5BENSG00000103018.122076.643802593.23510-0.320502.714901.50690K562ABCF1
CYB5BENSG00000103018.122333.468901655.537300.4951010.424909.41490K562AGGF1
CYB5BENSG00000103018.122683.664501722.664000.639509.794108.46970K562AKAP8L
CYB5BENSG00000103018.121751.257302944.28450-0.7495012.5525011.43280K562AQR
CYB5BENSG00000103018.122218.662901807.493600.295603.480802.44460K562ATP5C1
CYB5BENSG00000103018.121509.364502063.27460-0.451003.207901.63900K562CKAP4
CYB5BENSG00000103018.122230.032802629.03220-0.237502.602801.52990K562CPEB4
CYB5BENSG00000103018.123341.563204131.11170-0.306002.526901.59500K562CELF1
CYB5BENSG00000103018.121703.666602720.46580-0.6752018.5916017.04510K562DDX47
CYB5BENSG00000103018.122515.157701853.695200.440107.611606.02890K562DKC1
CYB5BENSG00000103018.121301.016701597.88010-0.296503.422702.06440K562EIF2S1
CYB5BENSG00000103018.12642.28530904.96160-0.494602.410401.47820K562EIF3A
CYB5BENSG00000103018.121097.782701368.67350-0.318203.199501.93780K562EIF4B
CYB5BENSG00000103018.122244.013603359.26800-0.5821014.2523012.22420K562EIF4G2
CYB5BENSG00000103018.121116.860401426.77530-0.353303.224601.84320K562EXOSC5
CYB5BENSG00000103018.122375.200301863.998700.349503.091302.19210K562FIP1L1
CYB5BENSG00000103018.12988.541101289.77610-0.383702.748301.83650K562FTO
CYB5BENSG00000103018.12931.349401568.64980-0.752104.874402.04840K562FXR2
CYB5BENSG00000103018.121520.685001906.84520-0.326503.788202.46210K562GLRX3
CYB5BENSG00000103018.121152.256901427.98070-0.309502.334001.60410K562GPKOW
CYB5BENSG00000103018.121418.539301874.36880-0.402004.534703.16620K562HNRNPA1
CYB5BENSG00000103018.121042.968501716.51910-0.7188011.3968010.25550K562HNRNPC
CYB5BENSG00000103018.121832.324802458.54380-0.424105.024603.55540K562HNRNPL
CYB5BENSG00000103018.121954.820601533.106800.350502.374101.51430K562HNRNPM
CYB5BENSG00000103018.122344.769101828.168800.358902.407501.64620K562KIF1C
CYB5BENSG00000103018.12638.376301219.26540-0.933509.366907.54200K562KRR1
CYB5BENSG00000103018.121518.798002029.27710-0.418004.891703.62690K562MATR3
CYB5BENSG00000103018.122770.794602048.012000.436005.678604.28710K562MBNL1
CYB5BENSG00000103018.121030.772801393.86010-0.435404.327703.21580K562METAP2
CYB5BENSG00000103018.121634.966702004.80680-0.294204.151303.17900K562MTPAP
CYB5BENSG00000103018.122237.395801435.508800.640202.842901.94620K562NAA15
CYB5BENSG00000103018.121617.900602227.47700-0.4613012.2016010.78790K562NSUN2
CYB5BENSG00000103018.121748.964101362.233700.360402.764602.01620K562PRPF8
CYB5BENSG00000103018.121134.065801539.04660-0.440504.011202.89470K562PSIP1
CYB5BENSG00000103018.122398.636901975.717700.279702.619801.97090K562PTBP1
CYB5BENSG00000103018.123367.439103819.67670-0.181802.153701.30530K562PUM2
CYB5BENSG00000103018.123827.556901708.393401.1637027.5860025.85760K562PUS1
CYB5BENSG00000103018.122711.221001664.585700.7037016.4361014.97640K562RBM15
CYB5BENSG00000103018.121473.085301894.13380-0.362703.223502.31050K562RBM22
CYB5BENSG00000103018.12942.970401209.92440-0.359602.444701.50970K562RPS3
CYB5BENSG00000103018.121785.620602198.01590-0.299803.698302.76360K562SF3A3
CYB5BENSG00000103018.121053.678401331.15560-0.337202.497601.53490K562SRFBP1
CYB5BENSG00000103018.121808.393502251.92060-0.316405.316704.06890K562SRPK2
CYB5BENSG00000103018.12820.924501168.16400-0.508905.257603.72320K562SRSF4
CYB5BENSG00000103018.121602.180902237.02930-0.481504.526402.85220K562STAU1
CYB5BENSG00000103018.12974.087701318.66580-0.437003.259402.15170K562SUPV3L1
CYB5BENSG00000103018.121591.402701890.82610-0.248702.023101.33010K562TIA1
CYB5BENSG00000103018.121051.900001480.30110-0.492904.247503.06730K562TIAL1
CYB5BENSG00000103018.121163.498601572.66800-0.434704.135602.93190K562TRIM56
CYB5BENSG00000103018.121940.523202361.84460-0.283504.164003.30010K562UPF1
CYB5BENSG00000103018.121579.738202101.59220-0.411808.059006.68570K562WDR43
CYB5BENSG00000103018.122438.572103316.80490-0.443805.295904.03680K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for CYB5B is not available on ENCORE database.





1 RBPs can affect the splicing of CYB5B :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SECYB5BENSG00000103018.12chr16+694929956949302469482017694820476949633269496805-0.085000.001730.01937excludedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for CYB5B is not avaliable on ENCORE database.