CDK18

General Information

Gene Name       : CDK18
Gene ID             : ENSG00000117266.15
Essential Gene : No

Functions

Localization

Domains (AlphaFold: CDK18)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878CDK18ENSG00000117266.150.000.170.09ENCSR000AEF
HepG2CDK18ENSG00000117266.1514.857.1310.99ENCSR985KAT
K562CDK18ENSG00000117266.150.440.340.39ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for CDK18 is not avaliable on ENCORE database.



Proteins bound to RNA
  • CDK18 RNA is bound by 18 proteins.  







eCLIP assay for CDK18 is not avaliable on ENCORE database.





18 proteins are bound to CDK18 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr1205493436205493486+3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.374737.82075HepG2PPIG
chr1205494269205494324+3'-UTR,5'-UTR,CDS,intron-Proximal5.275616.46301HepG2PPIG
chr1205498649205498709+3'-UTR,CDS,intron-Proximal3.233803.11596HepG2GRWD1
chr1205501101205501154+3'-UTR3.844803.19379HepG2AKAP1
chr1205497221205497288+3'-UTR,CDS3.692754.51003HepG2PPIG
chr1205492524205492628+3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.989509.88830HepG2SF3B4
chr1205496927205496975+3'-UTR,CDS3.849944.96634HepG2PPIG
chr1205495949205496006+3'-UTR,5'-UTR,CDS,intron-Proximal4.3268811.59516HepG2EFTUD2
chr1205501149205501229+3'-UTR4.053973.95192HepG2UPF1
chr1205501308205501373+3'-UTR3.700629.25511HepG2ZC3H11A
chr1205492540205492593+3'-UTR,5'-UTR,intron-Distal,intron-Proximal3.597475.76899HepG2EFTUD2
chr1205498649205498705+3'-UTR,CDS,intron-Proximal3.673684.77136HepG2PPIG
chr1205501108205501157+3'-UTR3.441804.34707HepG2HNRNPK
chr1205501482205501607+3'-UTR3.7794211.66766HepG2HNRNPK
chr1205495926205496014+3'-UTR,5'-UTR,CDS,intron-Proximal3.9080621.87183HepG2PRPF8
chr1205500564205500619+3'-UTR3.423924.51003HepG2PPIG
chr1205501315205501428+3'-UTR4.521625.31599HepG2AKAP1
chr1205500726205500846+3'-UTR3.554527.43650HepG2LSM11
chr1205499771205499835+3'-UTR,CDS,intron-Proximal3.639896.00907HepG2PPIG
chr1205495916205495998+3'-UTR,5'-UTR,CDS,intron-Proximal4.360586.36347HepG2PPIG
chr1205495191205495216+3'-UTR,5'-UTR,CDS,intron-Proximal3.835933.59112HepG2PPIG
chr1205498651205498725+3'-UTR,CDS,intron-Proximal3.2719710.15419HepG2PRPF8
chr1205500665205500708+3'-UTR3.546533.85127HepG2GRWD1
chr1205495216205495308+3'-UTR,5'-UTR,CDS,intron-Proximal3.229315.80035HepG2PPIG
chr1205496975205497047+3'-UTR,CDS,intron-Proximal3.912705.86107HepG2PPIG
chr1205499402205499470+3'-UTR,CDS,intron-Distal3.748084.24574HepG2PABPN1
chr1205495249205495307+3'-UTR,5'-UTR,CDS3.402243.90804HepG2GRWD1
chr1205492319205492372+3'-UTR,CDS,intron-Distal,intron-Proximal3.847414.13746HepG2PPIG
chr1205498507205498555+3'-UTR,CDS3.834644.41267HepG2PPIG
chr1205500471205500510+3'-UTR,CDS,intron-Proximal4.554084.04622HepG2GRWD1
chr1205497210205497270+3'-UTR,CDS3.215043.09811HepG2GRWD1
chr1205501574205501653+3'-UTR3.219923.75704HepG2LSM11
chr1205492430205492535+3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.102763.37567HepG2HNRNPK
chr1205501487205501587+3'-UTR5.366105.36996HepG2PCBP2
chr1205473950205474007+5'-UTR,intron-Proximal3.375206.51348HepG2CSTF2T
chr1205473741205473830+5'-UTR3.5725012.47473HepG2CSTF2T
chr1205473742205473835+5'-UTR6.3190621.84366HepG2PCBP2
chr1205473732205473835+5'-UTR5.148897.25683HepG2PCBP1
chr1205474521205474564+intron-Distal3.613735.39685HepG2CSTF2T
chr1205474636205474729+intron-Distal3.773156.02098HepG2PRPF4
chr1205474244205474273+intron-Distal4.163674.10339HepG2CSTF2T
chr1205474644205474697+intron-Distal3.730455.32871HepG2CSTF2T
chr1205487173205487271+intron-Distal5.3095510.55930HepG2RBFOX2
chr1205474654205474708+intron-Distal3.503713.25786HepG2FAM120A
chr1205474657205474739+intron-Distal4.708425.14122HepG2PCBP2
chr1205474063205474112+intron-Distal,intron-Proximal3.390533.00221HepG2CSTF2T
chr1205496747205496813+intron-Distal3.9965511.57547HepG2SF3B4
chr1205495635205495714+intron-Distal,intron-Proximal3.507184.36184HepG2PRPF4
chr1205486859205486978+intron-Distal3.347534.39383HepG2HNRNPK
chr1205498385205498439+intron-Proximal4.218553.31322HepG2SF3B4
chr1205495985205496053+intron-Proximal3.776264.81289HepG2RBM22
chr1205496006205496046+intron-Proximal3.979194.12229HepG2EFTUD2
chr1205497349205497393+intron-Proximal4.604944.04755HepG2RBM22
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for CDK18 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for CDK18 is not available on ENCORE database.

  • 107 RBPs can affect the levels of CDK18.  








The Knockdown/knockout RNA-Seq assay for CDK18 is not available on ENCORE database.





107 RBPs can affect the gene expression of CDK18 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
CDK18ENSG00000117266.111058.838202291.03720-1.113504.020402.89810HepG2ABCF1
CDK18ENSG00000117266.112053.764101671.301400.297201.953101.42570HepG2ACO1
CDK18ENSG00000117266.11428.78680871.78640-1.0237010.498608.73240HepG2ADAR
CDK18ENSG00000117266.11953.358001897.34620-0.992903.005402.45350HepG2AKAP1
CDK18ENSG00000117266.112070.404601714.230300.272303.558802.79730HepG2AUH
CDK18ENSG00000117266.11993.38570496.807300.9996010.309608.71930HepG2BCLAF1
CDK18ENSG00000117266.111686.05010962.158500.8092012.3634011.22050HepG2BOP1
CDK18ENSG00000117266.111498.430702307.30830-0.622803.936701.61300HepG2CDC40
CDK18ENSG00000117266.111730.78290883.279700.9704016.1517014.65560HepG2CPSF6
CDK18ENSG00000117266.11164.07050353.09290-1.105706.783405.20950HepG2CSTF2
CDK18ENSG00000117266.111756.597301310.957700.422107.409906.28140HepG2DAZAP1
CDK18ENSG00000117266.111145.046601545.65270-0.432805.226004.12820HepG2DDX19B
CDK18ENSG00000117266.11573.68040938.74150-0.710502.172201.56330HepG2DDX21
CDK18ENSG00000117266.11501.59380920.18160-0.875402.559101.68300HepG2DDX24
CDK18ENSG00000117266.111516.41470562.320301.4311020.9533019.12320HepG2DDX55
CDK18ENSG00000117266.112018.401801003.040201.008707.896006.28650HepG2DDX59
CDK18ENSG00000117266.112623.120701561.902600.747903.188702.53040HepG2DDX6
CDK18ENSG00000117266.11984.687901598.94780-0.6994015.4552014.12950HepG2DKC1
CDK18ENSG00000117266.111965.51020877.820801.1628028.4752026.49450HepG2DNAJC21
CDK18ENSG00000117266.111838.23760870.128501.0789046.2206043.83560HepG2DNAJC2
CDK18ENSG00000117266.11616.870401253.44810-1.0229015.0534013.17530HepG2EEF2
CDK18ENSG00000117266.113445.035201500.525601.1990014.5514013.25890HepG2EIF2S1
CDK18ENSG00000117266.111611.054201968.16090-0.288803.781503.09700HepG2ETF1
CDK18ENSG00000117266.111175.458101633.04100-0.474302.656201.83850HepG2EWSR1
CDK18ENSG00000117266.111250.96120909.514800.459805.141203.51110HepG2FAM120A
CDK18ENSG00000117266.111422.55360884.864800.684902.698401.69410HepG2FTO
CDK18ENSG00000117266.112356.556801542.324800.611502.269201.55100HepG2FUBP3
CDK18ENSG00000117266.11483.11200905.85670-0.9069010.868609.17070HepG2GEMIN5
CDK18ENSG00000117266.11619.79470863.02890-0.477602.520001.55420HepG2GNB2L1
CDK18ENSG00000117266.112039.913001001.172501.0267015.2566013.87240HepG2GPKOW
CDK18ENSG00000117266.112149.806501595.533000.430107.818106.27750HepG2HDGF
CDK18ENSG00000117266.11494.32950886.23120-0.8422010.175409.05260HepG2HNRNPA1
CDK18ENSG00000117266.111513.115501204.928400.328503.832502.75870HepG2HNRNPA2B1
CDK18ENSG00000117266.11632.76970985.78800-0.639604.255703.40900HepG2HNRNPC
CDK18ENSG00000117266.112041.69620980.216701.0585036.8814034.77690HepG2HNRNPF
CDK18ENSG00000117266.111525.925501194.106200.353706.233405.25950HepG2HNRNPL
CDK18ENSG00000117266.112692.46330955.445901.4946037.3301035.43380HepG2HNRNPLL
CDK18ENSG00000117266.111283.96240979.269100.390705.260904.44590HepG2HNRNPU
CDK18ENSG00000117266.111572.94920965.230600.704406.376305.32110HepG2IGF2BP1
CDK18ENSG00000117266.111912.074601000.287600.9346038.3378036.05990HepG2ILF2
CDK18ENSG00000117266.112811.250001887.890800.574302.586301.31940HepG2ILF3
CDK18ENSG00000117266.112348.528301587.191200.565202.220601.33460HepG2KHSRP
CDK18ENSG00000117266.111764.190101527.695600.207502.523201.54710HepG2KIF1C
CDK18ENSG00000117266.111159.215301838.53280-0.665403.027502.15560HepG2LARP4
CDK18ENSG00000117266.11911.305101674.64840-0.877902.423601.80890HepG2MAGOH
CDK18ENSG00000117266.11683.946201683.79050-1.299804.290203.52090HepG2MATR3
CDK18ENSG00000117266.111994.95810974.635601.0333010.539208.63470HepG2MTPAP
CDK18ENSG00000117266.112350.778401571.234600.581103.281701.95310HepG2NAA15
CDK18ENSG00000117266.11976.691801723.26560-0.819202.230101.65870HepG2NCBP2
CDK18ENSG00000117266.111856.016701299.956400.513605.431204.36900HepG2NOL12
CDK18ENSG00000117266.111530.85650907.269500.754603.207801.64790HepG2NOLC1
CDK18ENSG00000117266.111599.29110847.253600.9165014.2587012.70270HepG2NSUN2
CDK18ENSG00000117266.112631.527301533.818400.778705.103304.13430HepG2PABPC4
CDK18ENSG00000117266.11789.86890969.28420-0.295302.706201.86660HepG2PARN
CDK18ENSG00000117266.111375.881301675.54800-0.284301.973801.44750HepG2PCBP1
CDK18ENSG00000117266.111280.20500873.426400.551502.860502.11340HepG2PPIL4
CDK18ENSG00000117266.111808.088001312.887000.461607.950506.72520HepG2PRPF4
CDK18ENSG00000117266.11435.22550970.10320-1.156405.477903.80610HepG2PRPF6
CDK18ENSG00000117266.111369.352701705.07470-0.316302.212001.71210HepG2PTBP1
CDK18ENSG00000117266.111615.563001240.991500.380403.934803.23790HepG2PUF60
CDK18ENSG00000117266.111276.797001702.30920-0.415007.284006.36330HepG2PUS1
CDK18ENSG00000117266.113724.627701846.335501.0123016.8445015.49300HepG2QKI
CDK18ENSG00000117266.114018.158802503.670400.6824015.4718013.71330HepG2RBM15
CDK18ENSG00000117266.11945.024801645.01930-0.7997017.0593015.99600HepG2RBM22
CDK18ENSG00000117266.11756.024601019.79580-0.431803.615102.47370HepG2RBM27
CDK18ENSG00000117266.11920.863401897.46650-1.0430013.2242012.20130HepG2NELFE
CDK18ENSG00000117266.111154.467801767.44610-0.614406.091305.22520HepG2RECQL
CDK18ENSG00000117266.11690.12350990.09660-0.520705.429804.60120HepG2RPS19
CDK18ENSG00000117266.11562.64440940.46820-0.741208.501307.15180HepG2RPS2
CDK18ENSG00000117266.11707.67130428.790000.722704.244903.29280HepG2RRP9
CDK18ENSG00000117266.111624.08430872.070900.8970028.2700026.52020HepG2SAFB2
CDK18ENSG00000117266.111276.08680993.561600.360902.502501.60640HepG2SERBP1
CDK18ENSG00000117266.11473.858601987.63900-2.0685040.6638038.03890HepG2SF3A3
CDK18ENSG00000117266.111613.35860945.648500.7706010.919009.60350HepG2SF3B1
CDK18ENSG00000117266.112171.365801190.084100.8674015.4438014.03130HepG2SLBP
CDK18ENSG00000117266.111628.60830909.572200.840308.104706.42370HepG2SMNDC1
CDK18ENSG00000117266.111447.97120868.086200.738005.940503.57440HepG2SND1
CDK18ENSG00000117266.111654.38430900.265300.877802.878401.53770HepG2SNRNP200
CDK18ENSG00000117266.112472.610901857.990600.412208.233107.49580HepG2SRFBP1
CDK18ENSG00000117266.11390.974101852.76560-2.2445038.7976037.47690HepG2SRSF1
CDK18ENSG00000117266.111889.14810963.040900.9720030.7076028.89010HepG2SRSF7
CDK18ENSG00000117266.111095.983801507.41300-0.459803.681303.06470HepG2SRSF9
CDK18ENSG00000117266.11667.694101613.17880-1.2726047.2503045.76670HepG2SSB
CDK18ENSG00000117266.112691.245301560.840200.785903.593702.53150HepG2SUPT6H
CDK18ENSG00000117266.111314.14730559.697701.2313015.6127014.23850HepG2SUPV3L1
CDK18ENSG00000117266.111976.56710931.512601.0852013.3148011.91230HepG2TARDBP
CDK18ENSG00000117266.111769.024803580.73410-1.017306.748205.16430HepG2TBRG4
CDK18ENSG00000117266.112013.826601530.177700.396104.380903.33670HepG2TIA1
CDK18ENSG00000117266.112035.68940960.053801.0842011.8071010.75960HepG2TRIM56
CDK18ENSG00000117266.111198.961201977.99680-0.722302.700902.07880HepG2U2AF1
CDK18ENSG00000117266.112173.049801283.529800.759506.893305.54340HepG2UBE2L3
CDK18ENSG00000117266.11613.09950330.573700.891007.970806.68510HepG2UCHL5
CDK18ENSG00000117266.112440.500501762.734200.469306.441605.44870HepG2UPF1
CDK18ENSG00000117266.11848.048001701.84710-1.0049030.9883029.31330HepG2UTP3
CDK18ENSG00000117266.11677.82150979.41670-0.531002.599501.57660HepG2XRCC6
CDK18ENSG00000117266.11829.307601295.64450-0.6437013.8332012.52260HepG2ZC3H8
CDK18ENSG00000117266.1173.3656012.592402.542407.511805.71200K562CNOT7
CDK18ENSG00000117266.11111.041504.351204.6734022.3337019.37490K562EFTUD2
CDK18ENSG00000117266.1137.7672012.192001.631102.588401.76260K562FMR1
CDK18ENSG00000117266.1134.0161010.336701.718302.774101.85860K562FTO
CDK18ENSG00000117266.11137.0297011.431603.583304.044203.08790K562GPKOW
CDK18ENSG00000117266.1156.6149010.984002.365705.411304.35060K562GRSF1
CDK18ENSG00000117266.1133.910509.138301.891602.848802.24420K562HNRNPC
CDK18ENSG00000117266.1142.4713011.245101.917103.790901.60240K562IGF2BP1
CDK18ENSG00000117266.1136.277209.768201.892802.853801.90220K562KRR1
CDK18ENSG00000117266.1139.8082011.159601.834702.798801.91690K562METAP2
CDK18ENSG00000117266.1190.971504.234404.4251016.3870014.54120K562PRPF8
CDK18ENSG00000117266.1140.018008.194802.287803.620102.56690K562PSIP1
CDK18ENSG00000117266.1149.4062016.540901.578602.683701.73720K562PUM2
CDK18ENSG00000117266.1116.460002.896902.506302.552201.74870K562RBM22
CDK18ENSG00000117266.1136.4268010.031801.860303.458402.14010K562SRSF7
CDK18ENSG00000117266.1143.8875011.231401.966203.449901.61230K562STIP1
CDK18ENSG00000117266.1121.931404.420102.310702.529401.38890K562XRN2
CDK18ENSG00000117266.1131.0434010.780301.525802.455101.65060K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for CDK18 is not available on ENCORE database.





19 RBPs can affect the splicing of CDK18 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SECDK18ENSG00000117266.11chr1+205498126205498224205497175205497296205498451205498557-0.159000.000010.00023excludedHepG2U2AF1
SECDK18ENSG00000117266.11chr1+205498126205498224205497175205497296205498451205498557-0.262000.000000.00000excludedHepG2U2AF2
A5SSCDK18ENSG00000117266.11chr1+205492610205492843205492610205492753205493359205493485-0.113000.000500.06983shorterHepG2NCBP2
A5SSCDK18ENSG00000117266.11chr1+205492610205492843205492610205492753205493359205493485-0.090000.000210.04608shorterHepG2TBRG4
RICDK18ENSG00000117266.11chr1+2054986482054994772054986482054986912054993862054994770.086000.000010.00148includedHepG2DDX6
RICDK18ENSG00000117266.11chr1+2054986482054994772054986482054986912054993862054994770.181000.004310.03037includedHepG2U2AF2
RICDK18ENSG00000117266.11chr1+2054984512054994772054984512054985572054986482054994770.069000.000010.00040includedHepG2PCBP1
RICDK18ENSG00000117266.11chr1+2054986482054994772054986482054986912054993862054994770.065000.002690.03468includedHepG2PCBP1
RICDK18ENSG00000117266.11chr1+2054922742054927532054922742054924252054926102054927530.216000.004050.04681includedHepG2PCBP1
RICDK18ENSG00000117266.11chr1+2054986482054994772054986482054986912054993862054994770.115000.000000.00001includedHepG2QKI
RICDK18ENSG00000117266.11chr1+2054922742054927532054922742054924252054926102054927530.188000.000670.00861includedHepG2TAF15
RICDK18ENSG00000117266.11chr1+2054986482054994772054986482054986912054993862054994770.230000.000020.00037includedHepG2U2AF1
RICDK18ENSG00000117266.11chr1+2054922742054927532054922742054924252054926102054927530.227000.000010.00031includedHepG2G3BP1
RICDK18ENSG00000117266.11chr1+2054986482054994772054986482054986912054993862054994770.081000.000030.00117includedHepG2G3BP1
RICDK18ENSG00000117266.11chr1+2054922742054927532054922742054924252054926102054927530.134000.003070.05470includedHepG2KHSRP
RICDK18ENSG00000117266.11chr1+2054986482054994772054986482054986912054993862054994770.116000.000000.00006includedHepG2NCBP2
RICDK18ENSG00000117266.11chr1+2054986482054994772054986482054986912054993862054994770.161000.000480.03189includedHepG2HNRNPU
RICDK18ENSG00000117266.11chr1+2054986482054994772054986482054986912054993862054994770.128000.000000.00001includedHepG2SF3B4
RICDK18ENSG00000117266.11chr1+2054922742054927532054922742054924252054926102054927530.254000.000030.00048includedHepG2SF3B4
RICDK18ENSG00000117266.11chr1+2054922742054927532054922742054924252054926102054927530.342000.000000.00000includedHepG2FUBP3
RICDK18ENSG00000117266.11chr1+2054984512054994772054984512054985572054986482054994770.085000.000180.00301includedHepG2RBM22
RICDK18ENSG00000117266.11chr1+2054922742054927532054922742054924252054926102054927530.188000.002960.04371includedHepG2SRSF9
RICDK18ENSG00000117266.11chr1+2054986482054994772054986482054986912054993862054994770.108000.000290.00737includedHepG2SRSF9
RICDK18ENSG00000117266.11chr1+2054986482054994772054986482054986912054993862054994770.164000.000000.00000includedHepG2HNRNPK
RICDK18ENSG00000117266.11chr1+2054986482054994772054986482054986912054993862054994770.091000.000100.00453includedHepG2PTBP1
RICDK18ENSG00000117266.11chr1+205498648205499477205498648205498691205499386205499477-0.095000.000070.02614excludedHepG2SUGP2
RICDK18ENSG00000117266.11chr1+2054922742054927532054922742054924252054926102054927530.401000.000000.00001includedHepG2LARP4

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for CDK18 is not avaliable on ENCORE database.