CASC4

General Information

Gene Name       : CASC4
Gene ID             : ENSG00000166734.19
Essential Gene : No

Functions

Localization

Domains (AlphaFold: CASC4)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878CASC4ENSG00000166734.1931.3526.5128.93ENCSR000AEF
HepG2CASC4ENSG00000166734.1916.0728.1222.09ENCSR985KAT
K562CASC4ENSG00000166734.1920.5722.7121.64ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for CASC4 is not avaliable on ENCORE database.



Proteins bound to RNA
  • CASC4 RNA is bound by 26 proteins.  







eCLIP assay for CASC4 is not avaliable on ENCORE database.





26 proteins are bound to CASC4 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr154467300344673032+3'-UTR,CDS,intron-Proximal4.5320612.00860K562IGF2BP1
chr154462087544620959+3'-UTR,CDS,intron-Proximal4.443306.01390HepG2GRWD1
chr154470698044707030+3'-UTR3.456328.28622K562PUM2
chr154462093444620986+3'-UTR,CDS,intron-Proximal4.177647.48753K562ZNF622
chr154462094444620992+3'-UTR,CDS,intron-Proximal3.047834.00731K562UCHL5
chr154462418544624235+3'-UTR,CDS,intron-Distal,intron-Proximal3.045143.55800HepG2BCLAF1
chr154467311844673165+3'-UTR,CDS4.909277.13565K562IGF2BP1
chr154467300344673171+3'-UTR,CDS,intron-Proximal3.653055.50254K562IGF2BP2
chr154467192344671987+3'-UTR,CDS,intron-Proximal3.863773.57526HepG2IGF2BP1
chr154470580044705950+3'-UTR,intron-Distal3.576466.13150K562IGF2BP1
chr154470649344706589+3'-UTR,intron-Distal5.9579017.74776HepG2LIN28B
chr154463003444630077+3'-UTR,5'-UTR,CDS3.098873.02345K562ZNF622
chr154470553344705662+3'-UTR,CDS,intron-Proximal3.144586.65384K562UCHL5
chr154462095444621004+3'-UTR,CDS,intron-Proximal3.422593.27569HepG2BCLAF1
chr154470553344705582+3'-UTR,CDS,intron-Proximal3.810054.93978HepG2BCLAF1
chr154467301244673161+3'-UTR,CDS3.773983.08588HepG2IGF2BP3
chr154470652944706596+3'-UTR,intron-Distal3.7596411.83667K562LIN28B
chr154462087944620944+3'-UTR,CDS,intron-Proximal3.421056.09767K562UCHL5
chr154467195844671986+3'-UTR,CDS3.543758.05487K562IGF2BP1
chr154470620444706254+3'-UTR,intron-Distal4.861069.89562K562PUM2
chr154467192344671987+3'-UTR,CDS,intron-Proximal3.289335.39086K562UCHL5
chr154463005444630104+3'-UTR,5'-UTR,CDS3.819364.51739HepG2BCLAF1
chr154467300144673159+3'-UTR,CDS,intron-Proximal4.6842413.85243HepG2IGF2BP1
chr154470782144707904+3'-UTR3.814063.07706HepG2TIAL1
chr154462088144620934+3'-UTR,CDS,intron-Proximal3.255565.44868K562ZNF622
chr154470782544707927+3'-UTR3.592095.80402HepG2FUBP3
chr154458107044581118+5'-UTR,intron-Proximal4.056173.11819K562EIF3G
chr154458117144581218+5'-UTR,intron-Distal,intron-Proximal3.048833.59926K562DDX3X
chr154458113444581215+5'-UTR,intron-Distal,intron-Proximal3.364345.64032HepG2EIF3H
chr154458102744581110+5'-UTR,intron-Proximal4.046807.99227HepG2RPS3
chr154458108544581158+5'-UTR,intron-Proximal3.395783.98124K562GEMIN5
chr154458107944581134+5'-UTR,intron-Proximal3.097504.49202K562MTPAP
chr154458132744581403+5'-UTR,CDS,intron-Proximal3.066729.00124K562ZNF622
chr154458105244581100+5'-UTR5.1470848.60145HepG2DDX3X
chr154458117544581224+5'-UTR,intron-Distal,intron-Proximal6.3404352.84806HepG2DDX3X
chr154458094844580993+5'-UTR4.0929219.82171HepG2DDX3X
chr154458110044581175+5'-UTR,intron-Proximal6.18520400.00000HepG2DDX3X
chr154458097244581021+5'-UTR3.819784.29728K562GEMIN5
chr154469519044695253+CDS,intron-Distal,intron-Proximal3.007523.17744HepG2GRWD1
chr154458123644581323+CDS,intron-Distal,intron-Proximal4.6172663.17937HepG2DDX3X
chr154458123544581330+CDS,intron-Distal,intron-Proximal4.100484.46002K562DDX24
chr154469520444695268+CDS,intron-Distal,intron-Proximal3.157825.10726K562UCHL5
chr154464782344647917+intron-Distal3.839013.19638K562SAFB2
chr154462108744621165+intron-Distal4.651574.64001HepG2U2AF2
chr154467754844677643+intron-Distal6.3918220.19514HepG2PCBP2
chr154460268344602810+intron-Distal4.625925.18391K562HNRNPL
chr154458807544588152+intron-Distal3.625284.70733K562HNRNPL
chr154462116844621257+intron-Distal3.414823.46531K562KHSRP
chr154462164044621739+intron-Distal3.873786.80241K562KHSRP
chr154467755144677631+intron-Distal4.540733.92947HepG2DDX59
chr154462398044624046+intron-Distal3.094773.17926K562KHSRP
chr154458815444588224+intron-Distal4.708455.85450K562HNRNPL
chr154469691644696983+intron-Distal4.210683.01017K562CPSF6
chr154458158944581649+intron-Proximal3.933876.66403K562TIA1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for CASC4 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for CASC4 is not available on ENCORE database.

  • 101 RBPs can affect the levels of CASC4.  








The Knockdown/knockout RNA-Seq assay for CASC4 is not available on ENCORE database.





101 RBPs can affect the gene expression of CASC4 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
CASC4ENSG00000166734.141509.396901943.37640-0.364605.584304.78050HepG2ACO1
CASC4ENSG00000166734.141576.293801952.49300-0.308804.136403.21210HepG2AKAP8L
CASC4ENSG00000166734.141654.001302488.80580-0.589508.307706.02680HepG2ATP5C1
CASC4ENSG00000166734.142534.693002066.174400.294702.896001.63640HepG2BUD13
CASC4ENSG00000166734.144255.372102265.819400.9092026.1392024.25530HepG2CALR
CASC4ENSG00000166734.141471.105802035.07330-0.468202.487601.76650HepG2CNOT7
CASC4ENSG00000166734.144117.667902554.021700.6890011.081509.80560HepG2CPSF6
CASC4ENSG00000166734.142755.395602170.457400.344204.852804.04540HepG2CELF1
CASC4ENSG00000166734.14921.447201797.33700-0.9639035.8068033.68020HepG2DDX19B
CASC4ENSG00000166734.141985.908701528.799500.377303.961602.85720HepG2DDX24
CASC4ENSG00000166734.143218.666302555.739500.332602.841501.81700HepG2DDX5
CASC4ENSG00000166734.14796.206801668.74970-1.0676042.1198039.83890HepG2DNAJC2
CASC4ENSG00000166734.141985.983901438.657300.465003.212302.01070HepG2AGO1
CASC4ENSG00000166734.14984.962101476.11040-0.583705.078403.88050HepG2EIF3D
CASC4ENSG00000166734.143488.833502205.652200.661404.942403.87290HepG2EIF4G2
CASC4ENSG00000166734.143561.919103029.589100.233403.134002.50050HepG2ETF1
CASC4ENSG00000166734.141590.498801899.01110-0.255802.022401.31080HepG2EWSR1
CASC4ENSG00000166734.142085.743502784.31960-0.416803.190302.37050HepG2FIP1L1
CASC4ENSG00000166734.141706.198703254.52810-0.9317012.7158011.33750HepG2FXR1
CASC4ENSG00000166734.142242.111603019.44520-0.429403.497002.75260HepG2G3BP1
CASC4ENSG00000166734.141342.986201699.79720-0.339903.026402.35330HepG2HNRNPA1
CASC4ENSG00000166734.142752.353302144.947300.359605.635004.38230HepG2HNRNPA2B1
CASC4ENSG00000166734.142224.286303056.54390-0.458604.952204.03890HepG2HNRNPK
CASC4ENSG00000166734.141885.401202126.28390-0.173502.094301.49710HepG2HNRNPL
CASC4ENSG00000166734.141641.140402879.87970-0.811302.788801.80310HepG2IGF2BP3
CASC4ENSG00000166734.142287.631903086.96990-0.432302.713201.72210HepG2KHSRP
CASC4ENSG00000166734.142528.148103255.66100-0.364902.829502.16730HepG2MAGOH
CASC4ENSG00000166734.142183.199803274.00410-0.584605.791704.90390HepG2MATR3
CASC4ENSG00000166734.142792.169202253.815000.308903.157402.29590HepG2MSI2
CASC4ENSG00000166734.141374.698603351.22410-1.2856019.5273017.94470HepG2NCBP2
CASC4ENSG00000166734.14907.949701359.30930-0.582202.698101.61860HepG2NONO
CASC4ENSG00000166734.141320.581101859.62410-0.493802.448901.62350HepG2PABPC1
CASC4ENSG00000166734.142184.162702876.47780-0.397207.792606.85640HepG2PCBP1
CASC4ENSG00000166734.141645.179602926.87540-0.8311028.3424026.94940HepG2PTBP1
CASC4ENSG00000166734.142814.580102209.274500.349203.345702.69920HepG2PUF60
CASC4ENSG00000166734.142857.116802343.489500.285802.803002.12780HepG2PUM2
CASC4ENSG00000166734.14858.607201979.45250-1.2050052.1891050.22610HepG2PUS1
CASC4ENSG00000166734.142609.596103169.98130-0.280603.353002.67450HepG2QKI
CASC4ENSG00000166734.142594.722701889.282900.457602.221101.58410HepG2RAVER1
CASC4ENSG00000166734.141942.805102532.17190-0.382205.849705.16650HepG2RBM22
CASC4ENSG00000166734.14695.733801594.66050-1.1966017.5921015.04360HepG2RCC2
CASC4ENSG00000166734.142053.146603257.37150-0.6659019.7270018.53810HepG2NELFE
CASC4ENSG00000166734.142218.475903033.72610-0.451509.926708.87010HepG2RECQL
CASC4ENSG00000166734.141636.684101130.021100.534304.778703.77800HepG2RRP9
CASC4ENSG00000166734.141461.363601672.62510-0.194802.052601.48460HepG2SAFB2
CASC4ENSG00000166734.14857.043101441.58960-0.750209.153107.46800HepG2SERBP1
CASC4ENSG00000166734.141658.537103090.21350-0.897809.658008.34020HepG2SF3A3
CASC4ENSG00000166734.142104.991603047.34170-0.5337013.4153012.26740HepG2SF3B4
CASC4ENSG00000166734.14642.256101950.58020-1.6027094.1258091.52870HepG2SMN1
CASC4ENSG00000166734.142458.223302859.98790-0.218402.925302.41450HepG2SRFBP1
CASC4ENSG00000166734.142489.560803180.72960-0.353507.055306.38310HepG2SRSF1
CASC4ENSG00000166734.141909.011102483.13430-0.379307.047506.30160HepG2SSB
CASC4ENSG00000166734.141323.638201776.02880-0.424102.687601.60460HepG2STIP1
CASC4ENSG00000166734.142560.867201765.557800.536403.489702.12550HepG2SUB1
CASC4ENSG00000166734.142573.413201880.422300.452506.075504.71220HepG2SUPT6H
CASC4ENSG00000166734.141811.863801473.908500.297702.009201.41910HepG2SUPV3L1
CASC4ENSG00000166734.143337.989902692.599500.309902.683701.96870HepG2TARDBP
CASC4ENSG00000166734.141590.622002710.83700-0.769102.895901.80380HepG2TBRG4
CASC4ENSG00000166734.14615.93780870.72660-0.499403.592902.73030HepG2UCHL5
CASC4ENSG00000166734.14974.536001349.81650-0.470002.275601.37190HepG2UPF2
CASC4ENSG00000166734.142284.843502645.89200-0.211702.817502.21610HepG2UTP3
CASC4ENSG00000166734.14851.522401450.89930-0.768808.506707.25050HepG2XRN2
CASC4ENSG00000166734.141158.989801813.51240-0.6459017.4634016.03020HepG2ZC3H8
CASC4ENSG00000166734.141985.620403014.07790-0.6021022.0100020.82820HepG2ZNF622
CASC4ENSG00000166734.141546.015202405.73580-0.6379016.7496015.47760K562AGGF1
CASC4ENSG00000166734.141011.319701304.37760-0.367104.390702.45330K562AKAP1
CASC4ENSG00000166734.141612.783102503.22700-0.634209.615808.30650K562AKAP8L
CASC4ENSG00000166734.142054.127502451.07080-0.254901.914201.40900K562AQR
CASC4ENSG00000166734.141662.635302626.39300-0.659608.997907.22700K562ATP5C1
CASC4ENSG00000166734.142422.352003098.68600-0.355205.601003.98170K562CPEB4
CASC4ENSG00000166734.145012.547603898.991200.362305.176903.83360K562CELF1
CASC4ENSG00000166734.141556.868802822.58280-0.8584015.5920012.46970K562DDX19B
CASC4ENSG00000166734.142680.429703205.94170-0.258303.578302.84940K562DDX47
CASC4ENSG00000166734.141103.533801339.94900-0.280002.653601.38510K562DDX6
CASC4ENSG00000166734.142028.716102693.96620-0.409204.409703.26670K562DKC1
CASC4ENSG00000166734.141133.79070827.334700.454503.899102.28550K562DNAJC21
CASC4ENSG00000166734.14833.170501221.28570-0.551705.112103.85100K562EFTUD2
CASC4ENSG00000166734.14870.068401307.68080-0.587804.807303.39650K562EIF3D
CASC4ENSG00000166734.141036.558801469.03870-0.503103.438202.55680K562EIF3G
CASC4ENSG00000166734.14859.090201205.25170-0.488506.139904.05770K562EWSR1
CASC4ENSG00000166734.141514.006402115.39330-0.482603.612202.63320K562FIP1L1
CASC4ENSG00000166734.141934.930701366.228900.502004.666903.13620K562FKBP4
CASC4ENSG00000166734.141017.636701435.93020-0.496807.481506.55100K562FXR1
CASC4ENSG00000166734.141311.857001804.98770-0.460405.243003.19370K562G3BP1
CASC4ENSG00000166734.141905.550401468.738700.375502.223601.60010K562G3BP2
CASC4ENSG00000166734.142154.021802897.41830-0.427705.252003.74440K562HNRNPL
CASC4ENSG00000166734.141316.588801739.80980-0.402102.724201.80140K562HNRNPM
CASC4ENSG00000166734.141436.938801920.14630-0.418204.249602.70190K562IGF2BP3
CASC4ENSG00000166734.142150.455102656.72530-0.305003.219102.32320K562KIF1C
CASC4ENSG00000166734.141958.403602542.99730-0.376903.687802.38470K562MAK16
CASC4ENSG00000166734.142487.999602976.17890-0.258502.349501.52220K562MBNL1
CASC4ENSG00000166734.144139.463803379.945100.292302.650101.54680K562MSI2
CASC4ENSG00000166734.141621.759802086.07040-0.363202.200901.43470K562NAA15
CASC4ENSG00000166734.141179.199501549.55430-0.394002.983901.48600K562NUSAP1
CASC4ENSG00000166734.141372.613801981.11070-0.529402.293301.40900K562PABPN1
CASC4ENSG00000166734.141315.094901765.47370-0.424904.258703.04000K562PCBP2
CASC4ENSG00000166734.141519.832602355.01660-0.631802.778501.33900K562PPP1R8
CASC4ENSG00000166734.14673.837501188.45020-0.8186010.045508.61230K562PRPF8
CASC4ENSG00000166734.14892.318501411.13340-0.661208.071906.35870K562PSIP1
CASC4ENSG00000166734.14935.256801927.72450-1.0435025.0905023.17110K562PTBP1
CASC4ENSG00000166734.14993.292502482.87330-1.3217031.6735029.81470K562PUS1
CASC4ENSG00000166734.141538.262402418.88850-0.6530013.9283012.59130K562RBM15
CASC4ENSG00000166734.141353.941201848.61640-0.449304.607103.49030K562RBM22
CASC4ENSG00000166734.141056.059501393.97770-0.400503.763202.17620K562RBM25
CASC4ENSG00000166734.14722.427701287.40590-0.8335013.7399011.54090K562RCC2
CASC4ENSG00000166734.14653.365001017.00900-0.638404.141702.20380K562SERBP1
CASC4ENSG00000166734.141136.618301811.59820-0.672502.912101.66610K562SF1
CASC4ENSG00000166734.141098.665801528.05540-0.475905.079303.90290K562SF3B4
CASC4ENSG00000166734.141435.070102888.88700-1.0094010.810907.56870K562SMN1
CASC4ENSG00000166734.141234.535902080.78680-0.753203.567502.10630K562SNRNP200
CASC4ENSG00000166734.14812.560701220.43370-0.586803.499502.31230K562SRFBP1
CASC4ENSG00000166734.141309.114401784.67410-0.447104.449003.06410K562SRSF5
CASC4ENSG00000166734.141166.769701443.12820-0.306702.731401.91800K562SYNCRIP
CASC4ENSG00000166734.141553.716401912.65100-0.299902.175001.54260K562TARDBP
CASC4ENSG00000166734.141351.579701844.94940-0.448905.376704.17920K562TIA1
CASC4ENSG00000166734.141300.089201810.27760-0.477605.069103.50500K562TRA2A
CASC4ENSG00000166734.142655.776802261.965400.231502.852901.56300K562TROVE2
CASC4ENSG00000166734.14851.533201424.61350-0.742407.800105.80770K562U2AF1
CASC4ENSG00000166734.14773.752101471.01190-0.9269018.9904016.82840K562U2AF2
CASC4ENSG00000166734.142864.052002515.475000.187102.208401.56220K562UPF1
CASC4ENSG00000166734.141710.768502152.41580-0.331303.263302.31680K562WDR3
CASC4ENSG00000166734.142169.852702904.61570-0.420804.957303.22590K562WRN
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for CASC4 is not available on ENCORE database.





10 RBPs can affect the splicing of CASC4 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SECASC4ENSG00000166734.14chr15+4469508444695252446730034467317444705533447079560.166000.000110.01631includedHepG2G3BP1
SECASC4ENSG00000166734.14chr15+446950844469525244673003446731744470553344707956-0.309000.000000.00000excludedK562SRSF1
SECASC4ENSG00000166734.14chr15+4469508444695252446730034467317444705533447079560.402000.000000.00000includedHepG2U2AF2
SECASC4ENSG00000166734.14chr15+446304344463051544629960446301054467188744671986-0.063000.000000.00007excludedHepG2U2AF2
SECASC4ENSG00000166734.14chr15+4469508444695252446730034467317444705533447079560.149000.000200.01767includedHepG2AKAP1
SECASC4ENSG00000166734.14chr15+4469508444695252446730034467317444705533447079560.411000.000000.00000includedHepG2SFPQ
SECASC4ENSG00000166734.14chr15+4469508444695252446730034467317444705533447079560.187000.000070.01001includedHepG2DDX6
SECASC4ENSG00000166734.14chr15+4469508444695252446730034467317444705533447079560.325000.000000.00183includedHepG2HNRNPUL1
SECASC4ENSG00000166734.14chr15+446950844469525244673003446731744470553344707956-0.243000.000000.00000excludedHepG2SRSF1
SECASC4ENSG00000166734.14chr15+4469508444695252446730474467317444705533447079560.215000.000010.00290includedHepG2TAF15
SECASC4ENSG00000166734.14chr15+446950844469525244673003446731744470553344707956-0.188000.000060.00387excludedK562HNRNPU
SECASC4ENSG00000166734.14chr15+4469508444695252446730034467317444705533447079560.189000.000010.00212includedHepG2SRSF9

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for CASC4 is not avaliable on ENCORE database.