TOB1

General Information

Gene Name       : TOB1
Gene ID             : ENSG00000141232.4
Essential Gene : No

Functions

Localization

Domains (AlphaFold: TOB1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878TOB1ENSG00000141232.46.096.546.31ENCSR000AEF
HepG2TOB1ENSG00000141232.432.1338.6735.40ENCSR985KAT
K562TOB1ENSG00000141232.410.7911.8211.30ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for TOB1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • TOB1 RNA is bound by 18 proteins.  







eCLIP assay for TOB1 is not avaliable on ENCORE database.





18 proteins are bound to TOB1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr174893967348939751-3'-UTR,intron-Distal4.344024.96433HepG2TIAL1
chr174893966748939706-3'-UTR,intron-Distal3.970035.35091K562PUM2
chr174893965148939759-3'-UTR,intron-Distal4.200886.36119HepG2KHSRP
chr174893995348940017-3'-UTR,intron-Distal3.960938.02416HepG2FUBP3
chr174894149348941538-3'-UTR,intron-Distal3.825643.18234K562BUD13
chr174893987648939953-3'-UTR,intron-Distal3.9749210.67208HepG2FUBP3
chr174893966248939755-3'-UTR,intron-Distal5.9531122.98651HepG2FUBP3
chr174893980548939881-3'-UTR,intron-Distal4.885068.44976K562PUM2
chr174893992548940043-3'-UTR,intron-Distal5.1324524.57473K562PUM2
chr174894363248943709-5'-UTR,intron-Distal,intron-Proximal5.5909351.93026HepG2DDX3X
chr174894366048943693-5'-UTR,intron-Distal4.287677.02261HepG2DDX6
chr174894352448943580-5'-UTR,intron-Distal5.3705315.31047HepG2DDX3X
chr174894341748943500-5'-UTR,intron-Distal3.6844822.84131HepG2DDX3X
chr174894335848943524-5'-UTR,intron-Distal3.595834.57030HepG2FTO
chr174894359548943644-5'-UTR,intron-Distal3.493907.91983HepG2DDX6
chr174894351948943710-5'-UTR,intron-Distal,intron-Proximal3.5649010.11483K562DDX3X
chr174894359448943632-5'-UTR,intron-Distal4.2808018.70677HepG2DDX3X
chr174894125148941286-CDS,intron-Distal3.345604.34695HepG2BCLAF1
chr174894086548940911-CDS,intron-Distal4.131267.18138HepG2RBM15
chr174894111348941199-CDS,intron-Distal3.491348.02162HepG2BCLAF1
chr174894079848940854-CDS,intron-Distal4.704865.89791K562RBM15
chr174894066348940713-CDS,intron-Distal,intron-Proximal3.200657.55544HepG2DDX6
chr174894062948940705-CDS,intron-Distal,intron-Proximal3.345133.04831K562RBM15
chr174894065548940713-CDS,intron-Distal,intron-Proximal3.556103.85040HepG2IGF2BP1
chr174894085448940981-CDS,intron-Distal3.490027.87999K562RBM15
chr174894066948940743-CDS,intron-Distal,intron-Proximal4.4822512.98006HepG2RBM15
chr174894113748941172-CDS,intron-Distal4.703014.86150HepG2RBM15
chr174894310548943166-intron-Distal3.7102411.19394HepG2EFTUD2
chr174894312048943173-intron-Distal4.219528.50130HepG2BUD13
chr174894324048943413-intron-Distal3.310165.42760HepG2XRN2
chr174894307848943193-intron-Distal3.086245.70836HepG2FAM120A
chr174894294648943011-intron-Distal4.234166.34163HepG2XRN2
chr174894311248943205-intron-Distal3.176334.67631HepG2PRPF4
chr174894326748943323-intron-Distal4.410446.75344HepG2EFTUD2
chr174894293348943024-intron-Distal3.738119.11312HepG2EFTUD2
chr174894336248943398-intron-Distal4.256274.90219HepG2AQR
chr174894323348943293-intron-Distal3.983663.03048HepG2GTF2F1
chr174894322048943308-intron-Distal3.325906.04937HepG2PRPF4
chr174894333848943402-intron-Distal5.6066012.96345HepG2EFTUD2
chr174894294148943006-intron-Distal4.210465.85562K562GEMIN5
chr174894305148943068-intron-Distal4.849314.52669HepG2EFTUD2
chr174894293848943016-intron-Distal3.285133.57220HepG2PRPF4
chr174894321448943267-intron-Distal3.330756.78376HepG2EFTUD2
chr174894308748943167-intron-Distal5.136408.73676HepG2GTF2F1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for TOB1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for TOB1 is not available on ENCORE database.

  • 102 RBPs can affect the levels of TOB1.  








The Knockdown/knockout RNA-Seq assay for TOB1 is not available on ENCORE database.





102 RBPs can affect the gene expression of TOB1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
TOB1ENSG00000141232.41469.618703511.42660-1.2566022.3940021.03990HepG2AKAP1
TOB1ENSG00000141232.41989.917802905.41390-0.546005.850504.73170HepG2ASCC1
TOB1ENSG00000141232.4853.912001207.13220-0.499403.543502.48520HepG2BCCIP
TOB1ENSG00000141232.42824.078002299.411300.296403.325402.49000HepG2CALR
TOB1ENSG00000141232.41317.514403086.71380-1.2283018.6283016.28970HepG2CCAR1
TOB1ENSG00000141232.42173.040002760.34220-0.345102.739301.97030HepG2CIRBP
TOB1ENSG00000141232.41376.920201737.21080-0.335305.485704.60920HepG2CKAP4
TOB1ENSG00000141232.41338.920702269.93000-0.761605.844404.73270HepG2CNOT7
TOB1ENSG00000141232.4924.376701184.30240-0.357502.836402.15170HepG2DDX21
TOB1ENSG00000141232.41583.843401159.038300.450405.078103.83310HepG2DDX24
TOB1ENSG00000141232.4687.666401110.49390-0.691404.975303.31120HepG2DDX27
TOB1ENSG00000141232.41639.519703363.68790-1.0368018.3259016.86490HepG2DDX3X
TOB1ENSG00000141232.4524.219101186.87040-1.1789015.8328014.18980HepG2DDX55
TOB1ENSG00000141232.46403.406703410.427700.908804.551703.30850HepG2DDX59
TOB1ENSG00000141232.42035.609801662.435300.292102.282201.65670HepG2DKC1
TOB1ENSG00000141232.41129.409601463.80940-0.374202.755801.64930HepG2EFTUD2
TOB1ENSG00000141232.41610.345701090.659500.562104.325402.92750HepG2AGO1
TOB1ENSG00000141232.41556.451303069.72060-0.9798014.2919012.86360HepG2EIF4A3
TOB1ENSG00000141232.41316.051402988.78920-1.1833015.8753014.31080HepG2EIF4B
TOB1ENSG00000141232.42821.349102207.980600.353605.579004.46120HepG2EIF4G1
TOB1ENSG00000141232.42333.756103410.86350-0.547505.023604.01470HepG2FIP1L1
TOB1ENSG00000141232.4997.826301740.03210-0.802307.141305.40880HepG2FUS
TOB1ENSG00000141232.41499.311003097.19630-1.0467019.0604017.42200HepG2FXR1
TOB1ENSG00000141232.41660.127902873.11590-0.7913010.297409.05650HepG2G3BP1
TOB1ENSG00000141232.42250.334903050.16490-0.438704.155503.05420HepG2G3BP2
TOB1ENSG00000141232.41626.668402056.87040-0.338504.740503.56870HepG2HNRNPA2B1
TOB1ENSG00000141232.41042.766801417.28130-0.442704.144503.30830HepG2HNRNPC
TOB1ENSG00000141232.42316.355501702.095600.444408.395607.23490HepG2HNRNPF
TOB1ENSG00000141232.41807.367202909.26160-0.6868010.111908.84870HepG2HNRNPK
TOB1ENSG00000141232.41677.022202038.80810-0.281804.777703.90960HepG2HNRNPL
TOB1ENSG00000141232.41862.454202353.50600-0.337603.306402.27450HepG2HNRNPM
TOB1ENSG00000141232.41148.808601407.91450-0.293403.487102.81490HepG2HNRNPU
TOB1ENSG00000141232.42332.066701676.079400.476406.155905.11730HepG2IGF2BP1
TOB1ENSG00000141232.41856.821702920.46390-0.653408.022506.93540HepG2IGF2BP2
TOB1ENSG00000141232.42231.238003098.27740-0.473604.388903.56510HepG2MAGOH
TOB1ENSG00000141232.41825.484203115.62190-0.771209.506208.39520HepG2MATR3
TOB1ENSG00000141232.41319.744802760.77860-1.0648026.4953024.38820HepG2MSI2
TOB1ENSG00000141232.41862.792903189.01530-0.7756010.322509.13890HepG2NCBP2
TOB1ENSG00000141232.41948.450302973.68520-0.609904.894102.98900HepG2NKRF
TOB1ENSG00000141232.4888.700702219.33370-1.3204045.6819043.01720HepG2NOL12
TOB1ENSG00000141232.44278.487202880.815700.570508.025706.79950HepG2NSUN2
TOB1ENSG00000141232.41548.049602840.04020-0.8755012.9605011.42600HepG2PABPC4
TOB1ENSG00000141232.4846.127701393.65090-0.7199015.3768013.65670HepG2PARN
TOB1ENSG00000141232.4853.048101178.71390-0.466504.965303.33780HepG2PKM
TOB1ENSG00000141232.41232.610001731.65100-0.490402.818701.59090HepG2PRPF6
TOB1ENSG00000141232.41240.983102854.35590-1.2017054.3896052.64550HepG2PTBP1
TOB1ENSG00000141232.41683.670002248.87050-0.417609.190908.24310HepG2PUM1
TOB1ENSG00000141232.41132.776001769.88910-0.6438016.2785015.00470HepG2PUS1
TOB1ENSG00000141232.41822.116003091.36250-0.7626019.1887017.75100HepG2QKI
TOB1ENSG00000141232.41746.989902179.34610-0.319002.538902.03700HepG2RBM22
TOB1ENSG00000141232.41566.768803176.63360-1.0197041.9901040.44670HepG2NELFE
TOB1ENSG00000141232.42009.040902958.58510-0.5584014.2547013.02530HepG2RECQL
TOB1ENSG00000141232.41048.568001386.85020-0.403403.387502.71580HepG2RPS19
TOB1ENSG00000141232.41322.11230905.643900.545704.322603.36300HepG2RRP9
TOB1ENSG00000141232.41772.641601253.836800.4995010.506409.37420HepG2SAFB2
TOB1ENSG00000141232.41718.727502971.77360-0.7900026.4259024.91880HepG2SF3B4
TOB1ENSG00000141232.41264.149601462.23060-0.210002.252901.66280HepG2SMN1
TOB1ENSG00000141232.42096.547403578.46040-0.771306.568305.35520HepG2SNRNP70
TOB1ENSG00000141232.42882.714502461.564500.227802.273101.80470HepG2SRFBP1
TOB1ENSG00000141232.4784.732101130.41790-0.526604.136502.20450HepG2SRP68
TOB1ENSG00000141232.41601.937703101.87980-0.9533040.8048039.45680HepG2SRSF1
TOB1ENSG00000141232.42332.466601672.249100.480009.821208.64850HepG2SRSF7
TOB1ENSG00000141232.41689.439302523.53720-0.5789015.4682014.35180HepG2SRSF9
TOB1ENSG00000141232.42020.223601485.559800.443402.424901.30240HepG2SUB1
TOB1ENSG00000141232.41542.641802378.86280-0.6249018.5659017.18550HepG2SUCLG1
TOB1ENSG00000141232.41941.209902788.06700-0.5223010.390309.41420HepG2TAF15
TOB1ENSG00000141232.42011.682502561.87870-0.348803.915902.92980HepG2TIA1
TOB1ENSG00000141232.41066.690201368.22180-0.359203.637703.08100HepG2TIAL1
TOB1ENSG00000141232.46273.147402917.913701.1042026.9234024.90220HepG2U2AF1
TOB1ENSG00000141232.41323.521902190.65880-0.727008.263806.78680HepG2UBE2L3
TOB1ENSG00000141232.42596.081903275.67350-0.335506.485205.49000HepG2UPF1
TOB1ENSG00000141232.41649.719003162.53030-0.9389038.9263037.04820HepG2UTP3
TOB1ENSG00000141232.42343.540301844.874600.345105.587504.68440HepG2ZC3H8
TOB1ENSG00000141232.42063.229003602.61040-0.8041040.6208039.16290HepG2ZNF622
TOB1ENSG00000141232.42382.065201588.100100.584804.554002.85920HepG2ZRANB2
TOB1ENSG00000141232.4695.02830404.873200.7795011.1630010.11810K562AGGF1
TOB1ENSG00000141232.4759.86170421.295100.8508010.503209.12380K562AKAP8L
TOB1ENSG00000141232.42574.81530493.871602.3822091.0276088.14840K562AQR
TOB1ENSG00000141232.4615.59200442.051500.477704.462203.27290K562ATP5C1
TOB1ENSG00000141232.4345.51140234.306000.560203.253202.09220K562CCAR1
TOB1ENSG00000141232.4652.49510483.825900.431403.559102.19740K562CCDC124
TOB1ENSG00000141232.4850.53790475.027600.8403010.433107.70420K562DDX19B
TOB1ENSG00000141232.4375.11490262.309600.516002.830701.48610K562DHX30
TOB1ENSG00000141232.4644.63030453.305300.507904.249103.13140K562DKC1
TOB1ENSG00000141232.4385.45090251.956500.613303.877502.27020K562DNAJC21
TOB1ENSG00000141232.4422.94040311.866400.439402.440601.58520K562EFTUD2
TOB1ENSG00000141232.4519.91330312.948600.732206.650205.38790K562EIF4A3
TOB1ENSG00000141232.4377.14840281.839200.420202.788801.62920K562EIF4B
TOB1ENSG00000141232.4995.06750680.259800.548607.569706.02990K562EIF4G2
TOB1ENSG00000141232.41232.06300805.402800.613206.434905.11030K562FMR1
TOB1ENSG00000141232.4470.92850325.455500.532904.367203.63110K562FXR1
TOB1ENSG00000141232.4569.17060334.042100.768704.382403.44840K562G3BP2
TOB1ENSG00000141232.4806.86510533.136500.597704.327802.90560K562GLRX3
TOB1ENSG00000141232.4986.01840755.788400.383502.898902.08620K562GPKOW
TOB1ENSG00000141232.4843.00840522.871200.689002.979401.70190K562HNRNPA2B1
TOB1ENSG00000141232.4561.63540355.049500.661504.436903.01160K562IGF2BP2
TOB1ENSG00000141232.4582.97670361.147000.690806.585604.62610K562IGF2BP3
TOB1ENSG00000141232.4690.74550447.077900.627504.667203.54700K562KIF1C
TOB1ENSG00000141232.4611.12050373.176600.711507.240805.85370K562MAGOH
TOB1ENSG00000141232.4877.82190500.843200.8095010.810308.81420K562MBNL1
TOB1ENSG00000141232.41140.76290725.120500.653607.891206.03630K562MSI2
TOB1ENSG00000141232.4683.44040560.512300.286002.092901.38450K562MTPAP
TOB1ENSG00000141232.4666.05290351.056700.923807.607705.85880K562NAA15
TOB1ENSG00000141232.4474.91610312.480800.603804.906903.26470K562NCBP2
TOB1ENSG00000141232.4511.59110303.480700.753305.918504.81980K562PRPF8
TOB1ENSG00000141232.41036.97050742.240000.482304.838003.76210K562PUF60
TOB1ENSG00000141232.41090.05360789.310100.465605.384303.85420K562PUM1
TOB1ENSG00000141232.41086.62650773.549900.490206.580505.08370K562PUM2
TOB1ENSG00000141232.4703.37120417.765400.751507.661506.80430K562PUS1
TOB1ENSG00000141232.4895.70100407.085701.1376012.6848011.41600K562RBM15
TOB1ENSG00000141232.4615.84790347.671900.824708.842807.20870K562RBM22
TOB1ENSG00000141232.4688.43610418.401900.718302.488701.37280K562SF1
TOB1ENSG00000141232.4877.96610614.493100.514705.805804.65800K562SF3A3
TOB1ENSG00000141232.41051.70060718.742900.549104.166202.95360K562SF3B1
TOB1ENSG00000141232.4479.83800347.021600.467403.302802.36790K562SF3B4
TOB1ENSG00000141232.4777.17310480.430500.693802.805201.56820K562SNRNP200
TOB1ENSG00000141232.4766.21260629.553000.283302.283401.42410K562SRPK2
TOB1ENSG00000141232.4486.30120355.427800.452202.963402.23440K562SRSF1
TOB1ENSG00000141232.4589.18630443.571500.409503.263401.98400K562SRSF7
TOB1ENSG00000141232.4614.32240462.189900.410403.066401.46450K562SRSF9
TOB1ENSG00000141232.4458.77280334.153500.457202.707801.91280K562U2AF2
TOB1ENSG00000141232.4737.06850556.356900.405702.942502.04870K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for TOB1 is not available on ENCORE database.






No RBPs affect the alternative splcing events of TOB1 on ENCORE database.





The Knockdown/knockout RNA-Seq assay for TOB1 is not avaliable on ENCORE database.