SGK2

General Information

Gene Name       : SGK2
Gene ID             : ENSG00000101049.15
Essential Gene : No

Functions

Localization

Domains (AlphaFold: SGK2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878SGK2ENSG00000101049.150.030.150.09ENCSR000AEF
HepG2SGK2ENSG00000101049.156.956.426.69ENCSR985KAT
K562SGK2ENSG00000101049.150.020.100.06ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for SGK2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • SGK2 RNA is bound by 13 proteins.  







eCLIP assay for SGK2 is not avaliable on ENCORE database.





13 proteins are bound to SGK2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr204218778542187838+5'-UTR,intron-Proximal6.4003237.34237HepG2PRPF8
chr204218773142187785+5'-UTR5.1908825.10329HepG2PRPF8
chr204218763242187829+5'-UTR,intron-Proximal3.264195.38934HepG2NCBP2
chr204219498742195114+5'-UTR,CDS,intron-Distal,intron-Proximal4.254754.24670HepG2SF3B4
chr204219391842193972+5'-UTR,intron-Distal,intron-Proximal3.930233.98203HepG2PRPF8
chr204219807242198150+CDS3.309003.47879HepG2PPIG
chr204220066642200755+CDS,intron-Proximal4.548068.11807HepG2PRPF8
chr204220066142200757+CDS,intron-Proximal3.985995.59977HepG2AQR
chr204219934242199412+CDS,intron-Proximal4.5044816.59281HepG2PRPF8
chr204219317642193205+intron-Distal3.451584.60552HepG2AGGF1
chr204219308742193138+intron-Distal4.6068921.06820HepG2HNRNPL
chr204219333042193423+intron-Distal5.5241912.10389K562HNRNPL
chr204219300542193053+intron-Distal3.641224.73828HepG2AGGF1
chr204219335342193456+intron-Distal3.3807714.43823HepG2AGGF1
chr204219339642193423+intron-Distal4.4634316.35898HepG2HNRNPL
chr204219317842193209+intron-Distal4.9597810.88845HepG2HNRNPL
chr204219335642193396+intron-Distal5.0485533.87739HepG2HNRNPL
chr204219330942193407+intron-Distal3.664659.01532HepG2XPO5
chr204219322942193327+intron-Distal3.4203712.71260HepG2AGGF1
chr204219347342193662+intron-Distal,intron-Proximal5.2557818.94927K562HNRNPL
chr204219313942193329+intron-Distal5.4047736.16658K562AGGF1
chr204218814742188250+intron-Distal3.515565.31346HepG2QKI
chr204218831342188384+intron-Distal3.030804.63569HepG2RBFOX2
chr204218806442188137+intron-Distal4.479428.76637HepG2QKI
chr204219272242192790+intron-Distal3.267774.66496HepG2AGGF1
chr204218806342188122+intron-Distal3.566614.18806HepG2U2AF2
chr204219355742193577+intron-Distal4.4820522.51499HepG2HNRNPL
chr204219323742193330+intron-Distal5.406589.55090K562HNRNPL
chr204218790342188098+intron-Distal5.3395149.03602HepG2PTBP1
chr204218798042188056+intron-Distal6.1984812.93612HepG2QKI
chr204219343642193551+intron-Distal5.9558521.87879K562AGGF1
chr204219324642193358+intron-Distal4.854929.13550HepG2GTF2F1
chr204218791142188003+intron-Distal4.573034.67693K562PTBP1
chr204219354842193555+intron-Distal4.0469017.24513HepG2HNRNPL
chr204219335842193426+intron-Distal4.444668.57449HepG2GTF2F1
chr204219353242193615+intron-Distal,intron-Proximal4.6381712.00938HepG2GTF2F1
chr204219332342193356+intron-Distal4.6232417.38528HepG2HNRNPL
chr204218793842187989+intron-Distal4.805634.64001HepG2U2AF2
chr204219305342193120+intron-Distal3.047854.68227HepG2AGGF1
chr204219352442193548+intron-Distal4.4086721.92852HepG2HNRNPL
chr204219344742193514+intron-Distal5.2328830.50853HepG2HNRNPL
chr204219322242193323+intron-Distal4.4820138.70908HepG2HNRNPL
chr204219345642193612+intron-Distal,intron-Proximal3.3508020.24635HepG2AGGF1
chr204219351942193524+intron-Distal4.8479920.52306HepG2HNRNPL
chr204219357742193658+intron-Distal,intron-Proximal5.0350934.05773HepG2HNRNPL
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for SGK2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for SGK2 is not available on ENCORE database.

  • 106 RBPs can affect the levels of SGK2.  








The Knockdown/knockout RNA-Seq assay for SGK2 is not available on ENCORE database.





106 RBPs can affect the gene expression of SGK2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
SGK2ENSG00000101049.10190.51560268.96820-0.497502.843302.22830HepG2ACO1
SGK2ENSG00000101049.10326.45040486.23900-0.574803.053302.49770HepG2AKAP1
SGK2ENSG00000101049.10556.38500270.180601.0421015.7726014.15180HepG2AKAP8L
SGK2ENSG00000101049.10712.48240402.323200.824407.819306.53130HepG2ASCC1
SGK2ENSG00000101049.10504.83360234.869801.1038011.316908.76220HepG2ATP5C1
SGK2ENSG00000101049.10675.05990317.439001.0884019.7114018.18530HepG2AUH
SGK2ENSG00000101049.10450.92540205.543201.133309.138407.63250HepG2BCLAF1
SGK2ENSG00000101049.101281.75390205.407202.6415082.7992080.58220HepG2BOP1
SGK2ENSG00000101049.10632.53520144.167902.1333045.1731042.84910HepG2CALR
SGK2ENSG00000101049.10416.72980188.484801.144607.420006.17540HepG2CNOT7
SGK2ENSG00000101049.10637.65550188.570901.7576013.6456012.25480HepG2CPSF6
SGK2ENSG00000101049.10237.43240146.104300.700403.279702.11560HepG2CSTF2
SGK2ENSG00000101049.10373.65440255.941600.545804.182203.42290HepG2CELF1
SGK2ENSG00000101049.10669.89480275.149601.2836029.0150027.10510HepG2DAZAP1
SGK2ENSG00000101049.10247.26450143.717100.782704.761703.26420HepG2DDX1
SGK2ENSG00000101049.10381.92500162.222101.2352012.0078010.71260HepG2DDX21
SGK2ENSG00000101049.10363.33030158.697001.1949011.462809.64790HepG2DDX24
SGK2ENSG00000101049.10429.76170217.618400.981605.833904.04260HepG2DDX27
SGK2ENSG00000101049.10888.50380465.782900.9316010.291709.15230HepG2DDX3X
SGK2ENSG00000101049.10395.22420232.602200.764704.077303.15780HepG2DDX55
SGK2ENSG00000101049.10510.78360193.940401.3970017.6584015.44440HepG2DDX5
SGK2ENSG00000101049.10285.63340400.11070-0.486202.214801.65620HepG2DDX6
SGK2ENSG00000101049.10564.73460135.920002.0547037.5688034.83960HepG2DHX30
SGK2ENSG00000101049.10462.52180257.313700.845905.387004.49900HepG2DKC1
SGK2ENSG00000101049.10257.21420134.272600.937704.905803.70900HepG2EEF2
SGK2ENSG00000101049.10366.25120149.340801.2941010.416908.39970HepG2AGO1
SGK2ENSG00000101049.10844.37070384.642501.1343014.3424013.06330HepG2EIF2S1
SGK2ENSG00000101049.101025.58490425.078301.2705017.4202015.82730HepG2EIF4A3
SGK2ENSG00000101049.10518.58520271.495400.9336012.5778011.04950HepG2EIF4G1
SGK2ENSG00000101049.10889.98450260.067501.774805.020803.94360HepG2EIF4G2
SGK2ENSG00000101049.10460.22460262.775200.808404.414203.36310HepG2EWSR1
SGK2ENSG00000101049.10277.43870154.565700.843805.415703.89820HepG2FASTKD2
SGK2ENSG00000101049.10319.55550193.597200.722903.636302.19020HepG2FKBP4
SGK2ENSG00000101049.10519.66600257.457801.013109.597406.68220HepG2FMR1
SGK2ENSG00000101049.10577.38700188.902701.611809.494607.64340HepG2FTO
SGK2ENSG00000101049.10158.71850274.42690-0.790004.791903.77240HepG2FUBP3
SGK2ENSG00000101049.10303.40250190.910300.668203.077201.90000HepG2FUS
SGK2ENSG00000101049.10243.80730428.87680-0.814805.921304.93520HepG2FXR1
SGK2ENSG00000101049.10582.48030397.851000.549903.525002.77860HepG2G3BP1
SGK2ENSG00000101049.10451.67150155.198801.5411017.9466015.39080HepG2GNB2L1
SGK2ENSG00000101049.10949.95950213.748402.1519041.4120039.30030HepG2GPKOW
SGK2ENSG00000101049.10277.25800144.051100.944505.810603.18050HepG2GRWD1
SGK2ENSG00000101049.10372.66160252.894700.559204.213103.09990HepG2HNRNPA2B1
SGK2ENSG00000101049.10369.30090158.252301.2225010.713109.42650HepG2HNRNPC
SGK2ENSG00000101049.10153.52200250.62490-0.707104.253603.43110HepG2HNRNPL
SGK2ENSG00000101049.10727.65230203.985101.8347030.7523029.02060HepG2HNRNPLL
SGK2ENSG00000101049.10574.82030271.836701.080309.599407.38940HepG2HSPD1
SGK2ENSG00000101049.10488.63700309.618600.658205.401504.42300HepG2IGF2BP1
SGK2ENSG00000101049.101160.65190404.408601.5209027.9587026.08590HepG2IGF2BP2
SGK2ENSG00000101049.10223.37750137.381500.701203.908701.97590HepG2CCAR2
SGK2ENSG00000101049.10507.30890271.639600.901103.908602.41610HepG2KRR1
SGK2ENSG00000101049.10658.60950232.126601.5044017.2813015.22660HepG2LARP4
SGK2ENSG00000101049.101050.30930429.026501.2916019.4896017.83290HepG2MAGOH
SGK2ENSG00000101049.10901.66350431.429201.0634011.8574010.61620HepG2MATR3
SGK2ENSG00000101049.10311.02090212.707600.548002.767601.95950HepG2MSI2
SGK2ENSG00000101049.10476.98050257.609400.888605.950603.84770HepG2NKRF
SGK2ENSG00000101049.10434.15440213.628601.023005.131503.61850HepG2NONO
SGK2ENSG00000101049.10454.75640208.538601.1247012.174309.26380HepG2NUP35
SGK2ENSG00000101049.10917.94930393.273101.2228017.2147015.46110HepG2PABPC4
SGK2ENSG00000101049.10106.61210155.60710-0.545502.039701.30350HepG2PARN
SGK2ENSG00000101049.10616.44260394.712700.643107.630106.70190HepG2PCBP1
SGK2ENSG00000101049.10313.92340180.722000.796504.147702.89330HepG2PCBP2
SGK2ENSG00000101049.1084.24390140.21520-0.735003.010802.24560HepG2PPIL4
SGK2ENSG00000101049.10776.39120179.392202.1136036.1874033.82890HepG2PRPF8
SGK2ENSG00000101049.10704.16790260.464101.4347017.4705016.14660HepG2PUF60
SGK2ENSG00000101049.10395.59790276.510500.516604.560103.83920HepG2PUM1
SGK2ENSG00000101049.10493.26200273.952500.8483010.801509.72070HepG2PUS1
SGK2ENSG00000101049.10338.25790434.96360-0.362801.953501.41430HepG2QKI
SGK2ENSG00000101049.10455.20600304.615500.579404.512203.89260HepG2RBM22
SGK2ENSG00000101049.10269.74580446.98560-0.728606.500805.73010HepG2NELFE
SGK2ENSG00000101049.10141.96100416.33060-1.5522021.5440020.10260HepG2RECQL
SGK2ENSG00000101049.10630.85330338.791000.896808.961307.84060HepG2RPLP0
SGK2ENSG00000101049.10260.21560171.321400.602902.351201.47940HepG2RPS10
SGK2ENSG00000101049.10182.05260106.061700.779403.354602.68590HepG2RPS19
SGK2ENSG00000101049.10281.20480169.048400.734104.235903.25430HepG2RPS2
SGK2ENSG00000101049.10484.67600189.354001.3558012.4744010.82840HepG2RPS3A
SGK2ENSG00000101049.10269.43610172.546100.642902.626501.58060HepG2RPS5
SGK2ENSG00000101049.10406.77390177.452001.196709.207607.89080HepG2RRP9
SGK2ENSG00000101049.10338.04340189.748900.833004.304302.38080HepG2RTF1
SGK2ENSG00000101049.10593.06400106.439702.4781043.6467040.52300HepG2SERBP1
SGK2ENSG00000101049.1090.41800201.89840-1.158906.346505.31540HepG2SF3B1
SGK2ENSG00000101049.10283.29010177.856600.671503.220202.17750HepG2SMNDC1
SGK2ENSG00000101049.10409.77040224.649700.867004.633503.61150HepG2SNRNP70
SGK2ENSG00000101049.10254.14520344.05650-0.437002.576202.08620HepG2SRFBP1
SGK2ENSG00000101049.10655.18710257.190001.3490027.8985026.19310HepG2SRSF5
SGK2ENSG00000101049.10511.82100308.933700.728206.483005.48980HepG2SRSF7
SGK2ENSG00000101049.10587.03150355.094500.725109.566708.64770HepG2SRSF9
SGK2ENSG00000101049.10729.18170298.730401.2873028.3598027.10610HepG2SSB
SGK2ENSG00000101049.10336.73610177.466700.924007.959406.42050HepG2SUPT6H
SGK2ENSG00000101049.101119.38970231.539902.2733043.4310041.39060HepG2SUPV3L1
SGK2ENSG00000101049.10497.19400198.852401.3220015.4092013.92820HepG2TARDBP
SGK2ENSG00000101049.10769.34050266.064701.5317010.919508.98320HepG2TBRG4
SGK2ENSG00000101049.10282.25230155.185700.862902.866501.85360HepG2TFIP11
SGK2ENSG00000101049.10239.38070360.47320-0.590603.815902.84150HepG2TIA1
SGK2ENSG00000101049.101203.29290152.755002.97760115.21020112.90420HepG2TIAL1
SGK2ENSG00000101049.10422.43280154.120601.4546022.6669021.25670HepG2TRIM56
SGK2ENSG00000101049.10336.17050254.489100.401502.071101.32510HepG2TUFM
SGK2ENSG00000101049.10390.38300224.835200.795905.257304.40690HepG2U2AF1
SGK2ENSG00000101049.10555.66160269.390301.044408.968007.42580HepG2UBE2L3
SGK2ENSG00000101049.101321.89660416.688501.6655067.2770064.86010HepG2UPF1
SGK2ENSG00000101049.10345.91990211.987800.706403.167102.09150HepG2UPF2
SGK2ENSG00000101049.10615.95730428.310200.524102.508801.50440HepG2UTP18
SGK2ENSG00000101049.10268.01770169.609700.660003.001401.85450HepG2XPO5
SGK2ENSG00000101049.10253.02720167.237400.597303.550702.80470HepG2ZC3H8
SGK2ENSG00000101049.10863.45450458.279900.9138020.1568019.01490HepG2ZNF622
SGK2ENSG00000101049.1023.683104.709502.330102.734001.68310K562CSTF2
SGK2ENSG00000101049.1053.6482016.953501.661903.165502.12470K562CELF1
SGK2ENSG00000101049.1030.881006.454402.258303.215002.57800K562HNRNPC
SGK2ENSG00000101049.1026.278908.150801.688802.275401.59280K562NSUN2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for SGK2 is not available on ENCORE database.





3 RBPs can affect the splicing of SGK2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SESGK2ENSG00000101049.10chr20+421936814219392642187607421877994219511242195171-0.172000.001040.07627excludedHepG2TBRG4
SESGK2ENSG00000101049.10chr20+422118184221201442208611422087014221349142214317-0.061000.001010.07040excludedHepG2DDX3X
SESGK2ENSG00000101049.10chr20+4221181842212014422086114220870142213491422143170.245000.000310.02691includedHepG2HNRNPL

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for SGK2 is not avaliable on ENCORE database.