SEPSECS

General Information

Gene Name       : SEPSECS
Gene ID             : ENSG00000109618.11
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: SEPSECS)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878SEPSECSENSG00000109618.114.143.974.05ENCSR000AEF
HepG2SEPSECSENSG00000109618.112.924.673.79ENCSR985KAT
K562SEPSECSENSG00000109618.115.535.345.44ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for SEPSECS is not avaliable on ENCORE database.



Proteins bound to RNA
  • SEPSECS RNA is bound by 6 proteins.  







eCLIP assay for SEPSECS is not avaliable on ENCORE database.





6 proteins are bound to SEPSECS RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr42512888725128979-3'-UTR,CDS,intron-Distal,intron-Proximal4.2582811.11870HepG2BCLAF1
chr42512396225124021-3'-UTR,intron-Distal4.360403.87930K562UPF1
chr42515847125158520-5'-UTR,CDS,intron-Distal,intron-Proximal5.080346.58593HepG2BCLAF1
chr42516194925162022-5'-UTR,CDS,intron-Distal,intron-Proximal4.181664.10386HepG2NCBP2
chr42515664025156752-5'-UTR,CDS,intron-Distal3.300627.74581HepG2BCLAF1
chr42516057725160663-5'-UTR,CDS,intron-Distal3.134604.79538HepG2BCLAF1
chr42515858925158726-5'-UTR,CDS,intron-Distal,intron-Proximal4.237274.31512K562KHSRP
chr42515855725158619-5'-UTR,CDS,intron-Distal,intron-Proximal4.227573.77802HepG2U2AF2
chr42514638825146443-5'-UTR,CDS,intron-Distal,intron-Proximal4.033785.06180HepG2BCLAF1
chr42513803725138114-intron-Distal3.846053.01445K562EXOSC5
chr42516089325161001-intron-Distal3.730684.79415HepG2KHSRP
chr42516090925160986-intron-Distal3.325024.56724K562KHSRP
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for SEPSECS is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for SEPSECS is not available on ENCORE database.

  • 104 RBPs can affect the levels of SEPSECS.  








The Knockdown/knockout RNA-Seq assay for SEPSECS is not available on ENCORE database.





104 RBPs can affect the gene expression of SEPSECS :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
SEPSECSENSG00000109618.7444.07330633.02990-0.511503.146602.14010HepG2ABCF1
SEPSECSENSG00000109618.7484.83220654.36530-0.432604.368803.63810HepG2ACO1
SEPSECSENSG00000109618.7668.941001259.84920-0.913309.863008.92560HepG2AKAP1
SEPSECSENSG00000109618.7525.55840657.39690-0.322902.559401.81840HepG2AKAP8L
SEPSECSENSG00000109618.7290.41680432.02370-0.573003.043802.05760HepG2BCCIP
SEPSECSENSG00000109618.7656.72170366.530100.841308.961407.96060HepG2BOP1
SEPSECSENSG00000109618.7817.31470541.847600.592906.059304.97360HepG2CALR
SEPSECSENSG00000109618.7486.60380712.16340-0.549503.118002.07860HepG2CCAR1
SEPSECSENSG00000109618.7358.71450990.37080-1.4651024.8125022.80650HepG2CIRBP
SEPSECSENSG00000109618.7547.56880758.08420-0.469305.103604.27830HepG2CELF1
SEPSECSENSG00000109618.7310.42070476.69840-0.618904.564503.71800HepG2DDX21
SEPSECSENSG00000109618.7455.94970321.754200.502802.785401.39040HepG2DDX28
SEPSECSENSG00000109618.7633.806601036.69780-0.709906.255905.35660HepG2DDX6
SEPSECSENSG00000109618.7720.02560466.722700.625405.999504.59480HepG2DHX30
SEPSECSENSG00000109618.7749.56960483.893200.631307.824306.69050HepG2DNAJC21
SEPSECSENSG00000109618.7346.81770471.28630-0.442402.212401.38600HepG2EEF2
SEPSECSENSG00000109618.7665.699601072.33450-0.687804.917504.01740HepG2EIF4B
SEPSECSENSG00000109618.71099.75760804.189400.451505.514204.39980HepG2EIF4G1
SEPSECSENSG00000109618.71123.45710770.383000.544204.933603.86450HepG2EIF4G2
SEPSECSENSG00000109618.7808.300001230.93230-0.606809.448708.44690HepG2ETF1
SEPSECSENSG00000109618.7605.77370454.358800.414802.861201.69780HepG2FASTKD2
SEPSECSENSG00000109618.7380.97550639.17600-0.746505.908404.82510HepG2FIP1L1
SEPSECSENSG00000109618.7719.47740337.060101.093805.280303.88370HepG2FTO
SEPSECSENSG00000109618.7741.91190491.617800.593605.603704.49680HepG2FUBP3
SEPSECSENSG00000109618.7521.852901111.22990-1.0904015.3415013.85180HepG2FXR1
SEPSECSENSG00000109618.7807.974401094.35590-0.437703.254202.28480HepG2G3BP2
SEPSECSENSG00000109618.7187.82850340.64840-0.858906.278404.93110HepG2GEMIN5
SEPSECSENSG00000109618.7518.41450795.79680-0.618303.746702.44940HepG2GRSF1
SEPSECSENSG00000109618.7820.29030624.700300.392904.260703.06720HepG2HDGF
SEPSECSENSG00000109618.7295.58180488.52940-0.724905.881004.98730HepG2HNRNPA1
SEPSECSENSG00000109618.7768.69680543.410100.500303.886603.07550HepG2HNRNPC
SEPSECSENSG00000109618.7599.102101043.80270-0.801009.469908.24010HepG2HNRNPK
SEPSECSENSG00000109618.7688.52820364.053900.919309.590808.49950HepG2HNRNPLL
SEPSECSENSG00000109618.7268.84600440.91460-0.713706.023104.68840HepG2HNRNPM
SEPSECSENSG00000109618.7379.53330539.81650-0.508204.946704.15580HepG2HNRNPU
SEPSECSENSG00000109618.7822.580701047.81970-0.349202.252701.63600HepG2IGF2BP2
SEPSECSENSG00000109618.7372.79430551.40280-0.564706.698305.60720HepG2ILF2
SEPSECSENSG00000109618.71587.80270838.074100.921808.740306.33540HepG2ILF3
SEPSECSENSG00000109618.7789.77580598.139900.400904.613803.30510HepG2KIF1C
SEPSECSENSG00000109618.7311.20190751.56810-1.2721010.575408.94790HepG2LARP4
SEPSECSENSG00000109618.7871.65010524.568100.732504.509202.37720HepG2LSM11
SEPSECSENSG00000109618.7714.146201111.61780-0.638405.850404.90710HepG2MAGOH
SEPSECSENSG00000109618.7469.893301117.84050-1.2503017.2065015.73950HepG2MATR3
SEPSECSENSG00000109618.7325.30280517.16520-0.668805.632304.51470HepG2MSI2
SEPSECSENSG00000109618.7623.45610371.225200.747904.365103.13280HepG2MTPAP
SEPSECSENSG00000109618.7670.97820472.653700.505404.346902.56100HepG2NIP7
SEPSECSENSG00000109618.7619.52640808.40530-0.383903.581002.71360HepG2NOL12
SEPSECSENSG00000109618.7434.90080322.782700.430002.245501.56940HepG2NSUN2
SEPSECSENSG00000109618.71222.86630785.736200.638003.544402.53040HepG2PABPC1
SEPSECSENSG00000109618.71528.151401018.964700.584605.550704.53960HepG2PABPC4
SEPSECSENSG00000109618.7361.29080534.31160-0.564505.427304.29580HepG2PARN
SEPSECSENSG00000109618.7501.84750957.29020-0.9317018.9666017.60990HepG2PCBP1
SEPSECSENSG00000109618.7735.83720501.817300.552103.966301.96010HepG2PHF6
SEPSECSENSG00000109618.7610.24500471.271800.372703.040202.23430HepG2PRPF4
SEPSECSENSG00000109618.7783.04660974.10820-0.315002.972902.40960HepG2PTBP1
SEPSECSENSG00000109618.7421.82490771.65590-0.8713011.2925010.19860HepG2PUF60
SEPSECSENSG00000109618.7665.90720819.10270-0.298703.260302.62750HepG2PUM1
SEPSECSENSG00000109618.71610.661401054.920000.610409.974008.89210HepG2QKI
SEPSECSENSG00000109618.7836.57170519.686100.686702.930602.20650HepG2RAVER1
SEPSECSENSG00000109618.71078.06270721.212700.579807.383206.07560HepG2RBM15
SEPSECSENSG00000109618.7633.119201028.84170-0.7005010.721009.84770HepG2RBM22
SEPSECSENSG00000109618.7605.782801084.06430-0.8396015.7945014.70170HepG2NELFE
SEPSECSENSG00000109618.7625.723601009.70330-0.6903011.2062010.09290HepG2RECQL
SEPSECSENSG00000109618.7545.18540383.315700.508103.088702.37360HepG2RPLP0
SEPSECSENSG00000109618.7169.18040372.26810-1.1378011.035709.90610HepG2RPS19
SEPSECSENSG00000109618.7284.56030581.30670-1.030606.494105.29890HepG2RPS2
SEPSECSENSG00000109618.7445.16480324.089200.457802.034401.35010HepG2RRP9
SEPSECSENSG00000109618.7600.88050480.723700.321802.543001.92110HepG2SAFB2
SEPSECSENSG00000109618.7320.46640614.85880-0.940107.671106.51150HepG2SF3A3
SEPSECSENSG00000109618.7558.89940360.357900.633104.932504.01290HepG2SF3B1
SEPSECSENSG00000109618.7845.108001014.11920-0.263002.126101.59750HepG2SF3B4
SEPSECSENSG00000109618.7345.88090560.59370-0.696709.011507.95640HepG2SMN1
SEPSECSENSG00000109618.7785.67950400.955500.970407.387206.10410HepG2SNRNP70
SEPSECSENSG00000109618.7835.230801058.54260-0.341803.526803.00910HepG2SRSF1
SEPSECSENSG00000109618.7727.300001008.97150-0.472306.199505.48830HepG2SSB
SEPSECSENSG00000109618.7542.86640866.47280-0.6746011.4901010.36910HepG2SUCLG1
SEPSECSENSG00000109618.71544.40900951.519600.6986013.5232012.42170HepG2TAF15
SEPSECSENSG00000109618.71180.09380874.253000.432703.173202.28300HepG2TIA1
SEPSECSENSG00000109618.7233.78750524.48970-1.1657015.8436014.82480HepG2TIAL1
SEPSECSENSG00000109618.7569.78150753.80300-0.403803.230102.27870HepG2TUFM
SEPSECSENSG00000109618.7258.57140387.15730-0.582402.538301.57970HepG2UPF2
SEPSECSENSG00000109618.7283.00290526.45240-0.8955010.987009.92150HepG2UTP3
SEPSECSENSG00000109618.7811.56350510.719000.668103.464902.03330HepG2XRCC5
SEPSECSENSG00000109618.7262.89310416.24570-0.663004.092403.21890HepG2XRN2
SEPSECSENSG00000109618.7326.88550465.08460-0.508704.418603.60080HepG2ZC3H8
SEPSECSENSG00000109618.7649.42760818.76740-0.334302.151201.57200K562AKAP8L
SEPSECSENSG00000109618.7745.87970956.47060-0.358802.912501.63800K562APOBEC3C
SEPSECSENSG00000109618.7434.15230946.87930-1.1250016.0022014.74920K562AQR
SEPSECSENSG00000109618.7681.83920938.56350-0.461002.882501.57370K562CIRBP
SEPSECSENSG00000109618.7575.31630737.67840-0.358602.396701.37430K562CPEB4
SEPSECSENSG00000109618.7217.81760438.48870-1.009405.019403.96830K562CPSF6
SEPSECSENSG00000109618.7940.39610763.128100.301202.420301.80570K562DDX47
SEPSECSENSG00000109618.7317.45530423.90680-0.417202.127301.32680K562EFTUD2
SEPSECSENSG00000109618.7403.98810578.41540-0.517804.105503.14510K562EIF3G
SEPSECSENSG00000109618.7383.64280636.21740-0.729807.235605.91390K562EIF4A3
SEPSECSENSG00000109618.7309.44990446.09310-0.527602.559101.73740K562FMR1
SEPSECSENSG00000109618.7314.16870661.64040-1.0745017.3531015.95000K562FXR1
SEPSECSENSG00000109618.71000.87060702.595400.510403.253502.47650K562G3BP2
SEPSECSENSG00000109618.7499.02820655.74570-0.394002.494001.77360K562GRSF1
SEPSECSENSG00000109618.7237.68440367.61680-0.629203.397002.35760K562HNRNPM
SEPSECSENSG00000109618.7473.85300724.05180-0.611706.998305.57490K562HNRNPU
SEPSECSENSG00000109618.7662.08340875.30390-0.402802.358901.43260K562IGF2BP2
SEPSECSENSG00000109618.7217.42710357.43100-0.717103.570602.49470K562KRR1
SEPSECSENSG00000109618.7598.02000920.33350-0.622006.449105.13810K562MAGOH
SEPSECSENSG00000109618.7641.53600918.53080-0.517804.477403.27720K562MATR3
SEPSECSENSG00000109618.7280.86470408.66140-0.541002.307901.51030K562METAP2
SEPSECSENSG00000109618.7427.30720552.74320-0.371302.895502.06740K562MTPAP
SEPSECSENSG00000109618.7629.57870818.94620-0.379402.659001.69940K562PCBP2
SEPSECSENSG00000109618.7650.61970421.596500.625904.522603.46090K562PCBP3
SEPSECSENSG00000109618.7492.48650323.385500.606704.873403.80790K562POLR2G
SEPSECSENSG00000109618.7299.79980412.50850-0.460402.217701.54250K562PRPF8
SEPSECSENSG00000109618.7552.84620894.13000-0.693607.070706.04560K562PTBP1
SEPSECSENSG00000109618.7617.442201182.69980-0.9377013.9285012.08600K562PUF60
SEPSECSENSG00000109618.71042.147401232.56940-0.242102.231801.36750K562PUM2
SEPSECSENSG00000109618.7509.96810857.59520-0.749907.640006.15450K562RBM22
SEPSECSENSG00000109618.7451.49900606.01140-0.424603.366402.47130K562SF3A3
SEPSECSENSG00000109618.7527.72520730.98440-0.470104.232203.16940K562SF3B4
SEPSECSENSG00000109618.7390.85730887.17550-1.1826016.0686014.08850K562TARDBP
SEPSECSENSG00000109618.7261.10950383.97370-0.556402.960701.99050K562TIAL1
SEPSECSENSG00000109618.7441.83620703.69380-0.671404.990103.91320K562U2AF2
SEPSECSENSG00000109618.7518.70210651.18420-0.328202.653801.95000K562UPF1
SEPSECSENSG00000109618.7295.82110430.42220-0.541003.105401.80140K562XRN2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for SEPSECS is not available on ENCORE database.





1 RBPs can affect the splicing of SEPSECS :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SESEPSECSENSG00000109618.7chr4-251612492516138625160574251607292516187725162016-0.400000.002890.04909excludedK562SRSF1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for SEPSECS is not avaliable on ENCORE database.